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Conserved domains on  [gi|1516240505|ref|WP_123213748|]
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ABC-ATPase domain-containing protein [Staphylococcus epidermidis]

Protein Classification

ABC-ATPase domain-containing protein( domain architecture ID 11459641)

ABC-ATPase domain-containing protein similar to Trypanosoma brucei kinetoplastid RNA (kRNA) editing factor MRB1590 that binds RNA

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG3044 COG3044
Predicted ATPase of the ABC class [General function prediction only];
1-564 0e+00

Predicted ATPase of the ABC class [General function prediction only];


:

Pssm-ID: 442278 [Multi-domain]  Cd Length: 569  Bit Score: 926.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505   1 MKSAQALEQILTSLDGQKYGAYKQIKDLYEFNLFKLRIDHIQADPFAPPSKMSVVIDRQQAKFPDSLLNSELKQRAVSDY 80
Cdd:COG3044     1 MKNKEELRKLLKRIDGKGYKAYKDIKGTYDFGDFTLFIDHVQGDPFASPSKIRVRIPQSIAGFPAELYDSPVRRIALEDY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505  81 LTRVFHKQIQSIVAQDK---KVSKIQIDSCGQEILERTAVVIKNHQIEARIEVGLPARGRTILGRIARHTFINVLPQIVE 157
Cdd:COG3044    81 LTRSFAQAIRKLASGRRgtgKSGLIAIDRPGQEVLERTAVLINEDYVEARFSVGLPARGRRILGREAAKLLFEELPRIVE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 158 NALCYRNINGSQLQQQVELMMDQEEIRQQLVKRDLVAFVANGAILPRKSGVSDLPMN-NAIEFKSPKQYEIVMKLSSGKV 236
Cdd:COG3044   161 ASLLYENLDAEALERHVELVEDQEYLRQQLKERGLVAFVADGSILPRESGVSDRPLKeNAVPFQSPESLEVEFELPNGGT 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 237 IKGMGIPKGITLIVGGGYHGKSTLLEALERGVYNHIAGDGREYVITNQDAMKIRAEDGRSIQNVNIQPFIDHLPGEKDTT 316
Cdd:COG3044   241 ITGMGIPEGITLIVGGGYHGKSTLLKALERGVYNHIPGDGREYVVTDPDAVKIRAEDGRSVEGVDISPFINNLPQGKDTR 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 317 HFSTENASGSTSQAANVMEALESQASLLLIDEDTSATNFMIRDGRMQRLIAPEKEPITPFSNKVKALYDDHNVSTILIVG 396
Cdd:COG3044   321 RFSTENASGSTSQAANIMEALEAGARLLLIDEDTSATNFMIRDARMQALVAKEKEPITPFIDRVRQLYEDLGVSTILVMG 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 397 GSGDYFDVADQVLMMDEYVLKDVTQHAKDIAQSDGYQRKVSSHNQFGHIPSRIPLRASFN-QKGKRDRFKAKGLNVVTYG 475
Cdd:COG3044   401 GSGDYFDVADTVIMMDEYRPRDVTEEAKAIAEEYPTGRKAEGGAPFGPITPRVPLPESLDpRRGKKVKIKARGLDEIQFG 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 476 KETIHISGLEQLVDDSQTQGLAMMLSYVKNELLDDKSTIVELTNCLYQRIEKHGLDVISNHHGHPGHLALPRKQEFIATL 555
Cdd:COG3044   481 RETIDLSAVEQLVDPSQTRAIAAALRYARKRYLDGRRSLREILDLIEEDIEEKGLDVLSPFRGHPGDLARPRRFELAAAL 560

                  ....*....
gi 1516240505 556 NRYRRLKIK 564
Cdd:COG3044   561 NRLRTLKVK 569
 
Name Accession Description Interval E-value
COG3044 COG3044
Predicted ATPase of the ABC class [General function prediction only];
1-564 0e+00

Predicted ATPase of the ABC class [General function prediction only];


Pssm-ID: 442278 [Multi-domain]  Cd Length: 569  Bit Score: 926.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505   1 MKSAQALEQILTSLDGQKYGAYKQIKDLYEFNLFKLRIDHIQADPFAPPSKMSVVIDRQQAKFPDSLLNSELKQRAVSDY 80
Cdd:COG3044     1 MKNKEELRKLLKRIDGKGYKAYKDIKGTYDFGDFTLFIDHVQGDPFASPSKIRVRIPQSIAGFPAELYDSPVRRIALEDY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505  81 LTRVFHKQIQSIVAQDK---KVSKIQIDSCGQEILERTAVVIKNHQIEARIEVGLPARGRTILGRIARHTFINVLPQIVE 157
Cdd:COG3044    81 LTRSFAQAIRKLASGRRgtgKSGLIAIDRPGQEVLERTAVLINEDYVEARFSVGLPARGRRILGREAAKLLFEELPRIVE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 158 NALCYRNINGSQLQQQVELMMDQEEIRQQLVKRDLVAFVANGAILPRKSGVSDLPMN-NAIEFKSPKQYEIVMKLSSGKV 236
Cdd:COG3044   161 ASLLYENLDAEALERHVELVEDQEYLRQQLKERGLVAFVADGSILPRESGVSDRPLKeNAVPFQSPESLEVEFELPNGGT 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 237 IKGMGIPKGITLIVGGGYHGKSTLLEALERGVYNHIAGDGREYVITNQDAMKIRAEDGRSIQNVNIQPFIDHLPGEKDTT 316
Cdd:COG3044   241 ITGMGIPEGITLIVGGGYHGKSTLLKALERGVYNHIPGDGREYVVTDPDAVKIRAEDGRSVEGVDISPFINNLPQGKDTR 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 317 HFSTENASGSTSQAANVMEALESQASLLLIDEDTSATNFMIRDGRMQRLIAPEKEPITPFSNKVKALYDDHNVSTILIVG 396
Cdd:COG3044   321 RFSTENASGSTSQAANIMEALEAGARLLLIDEDTSATNFMIRDARMQALVAKEKEPITPFIDRVRQLYEDLGVSTILVMG 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 397 GSGDYFDVADQVLMMDEYVLKDVTQHAKDIAQSDGYQRKVSSHNQFGHIPSRIPLRASFN-QKGKRDRFKAKGLNVVTYG 475
Cdd:COG3044   401 GSGDYFDVADTVIMMDEYRPRDVTEEAKAIAEEYPTGRKAEGGAPFGPITPRVPLPESLDpRRGKKVKIKARGLDEIQFG 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 476 KETIHISGLEQLVDDSQTQGLAMMLSYVKNELLDDKSTIVELTNCLYQRIEKHGLDVISNHHGHPGHLALPRKQEFIATL 555
Cdd:COG3044   481 RETIDLSAVEQLVDPSQTRAIAAALRYARKRYLDGRRSLREILDLIEEDIEEKGLDVLSPFRGHPGDLARPRRFELAAAL 560

                  ....*....
gi 1516240505 556 NRYRRLKIK 564
Cdd:COG3044   561 NRLRTLKVK 569
ABC_ATPase pfam09818
ATPase of the ABC class; This is the C-terminal ATPase domain from bacterial ABC class ATPases. ...
166-448 0e+00

ATPase of the ABC class; This is the C-terminal ATPase domain from bacterial ABC class ATPases. This entry also includes MRB1590 from Trypanosoma brucei brucei has a central ATPase domain homologous to this domain.


Pssm-ID: 462914  Cd Length: 282  Bit Score: 512.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 166 NGSQLQQQVELMMDQEEIRQQLVKRDLVAFVANGAILPRKSGVSDLPMNNAIEFKSPKQYEIVMKLSSGKVIKGMGIPKG 245
Cdd:pfam09818   1 DEEALERHVELVEDQEHLRSQLAELGLVAFVANGSILPRESGVSDRPLKGAVPFESPESLEVEIELPNGGTVSGMGIPKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 246 ITLIVGGGYHGKSTLLEALERGVYNHIAGDGREYVITNQDAMKIRAEDGRSIQNVNIQPFIDHLPGEKDTTHFSTENASG 325
Cdd:pfam09818  81 ITLIVGGGFHGKSTLLEALERGVYNHIPGDGREFVVTDPDAVKIRAEDGRSVHGVDISPFINNLPPGKDTTDFSTEDASG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 326 STSQAANVMEALESQASLLLIDEDTSATNFMIRDGRMQRLIAPEKEPITPFSNKVKALYDDHNVSTILIVGGSGDYFDVA 405
Cdd:pfam09818 161 STSQAANIMEALEAGASLLLIDEDTSATNFMIRDERMQALVSKDKEPITPFVDRVRSLYDDLGVSTILVVGGSGDYLDVA 240
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1516240505 406 DQVLMMDEYVLKDVTQHAKDIAQSDGYQRKVSSHnQFGHIPSR 448
Cdd:pfam09818 241 DTVILMDEYRPSDVTEEAKEIAEELPTGRYEEAS-KFGPPRPR 282
 
Name Accession Description Interval E-value
COG3044 COG3044
Predicted ATPase of the ABC class [General function prediction only];
1-564 0e+00

Predicted ATPase of the ABC class [General function prediction only];


Pssm-ID: 442278 [Multi-domain]  Cd Length: 569  Bit Score: 926.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505   1 MKSAQALEQILTSLDGQKYGAYKQIKDLYEFNLFKLRIDHIQADPFAPPSKMSVVIDRQQAKFPDSLLNSELKQRAVSDY 80
Cdd:COG3044     1 MKNKEELRKLLKRIDGKGYKAYKDIKGTYDFGDFTLFIDHVQGDPFASPSKIRVRIPQSIAGFPAELYDSPVRRIALEDY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505  81 LTRVFHKQIQSIVAQDK---KVSKIQIDSCGQEILERTAVVIKNHQIEARIEVGLPARGRTILGRIARHTFINVLPQIVE 157
Cdd:COG3044    81 LTRSFAQAIRKLASGRRgtgKSGLIAIDRPGQEVLERTAVLINEDYVEARFSVGLPARGRRILGREAAKLLFEELPRIVE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 158 NALCYRNINGSQLQQQVELMMDQEEIRQQLVKRDLVAFVANGAILPRKSGVSDLPMN-NAIEFKSPKQYEIVMKLSSGKV 236
Cdd:COG3044   161 ASLLYENLDAEALERHVELVEDQEYLRQQLKERGLVAFVADGSILPRESGVSDRPLKeNAVPFQSPESLEVEFELPNGGT 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 237 IKGMGIPKGITLIVGGGYHGKSTLLEALERGVYNHIAGDGREYVITNQDAMKIRAEDGRSIQNVNIQPFIDHLPGEKDTT 316
Cdd:COG3044   241 ITGMGIPEGITLIVGGGYHGKSTLLKALERGVYNHIPGDGREYVVTDPDAVKIRAEDGRSVEGVDISPFINNLPQGKDTR 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 317 HFSTENASGSTSQAANVMEALESQASLLLIDEDTSATNFMIRDGRMQRLIAPEKEPITPFSNKVKALYDDHNVSTILIVG 396
Cdd:COG3044   321 RFSTENASGSTSQAANIMEALEAGARLLLIDEDTSATNFMIRDARMQALVAKEKEPITPFIDRVRQLYEDLGVSTILVMG 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 397 GSGDYFDVADQVLMMDEYVLKDVTQHAKDIAQSDGYQRKVSSHNQFGHIPSRIPLRASFN-QKGKRDRFKAKGLNVVTYG 475
Cdd:COG3044   401 GSGDYFDVADTVIMMDEYRPRDVTEEAKAIAEEYPTGRKAEGGAPFGPITPRVPLPESLDpRRGKKVKIKARGLDEIQFG 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 476 KETIHISGLEQLVDDSQTQGLAMMLSYVKNELLDDKSTIVELTNCLYQRIEKHGLDVISNHHGHPGHLALPRKQEFIATL 555
Cdd:COG3044   481 RETIDLSAVEQLVDPSQTRAIAAALRYARKRYLDGRRSLREILDLIEEDIEEKGLDVLSPFRGHPGDLARPRRFELAAAL 560

                  ....*....
gi 1516240505 556 NRYRRLKIK 564
Cdd:COG3044   561 NRLRTLKVK 569
ABC_ATPase pfam09818
ATPase of the ABC class; This is the C-terminal ATPase domain from bacterial ABC class ATPases. ...
166-448 0e+00

ATPase of the ABC class; This is the C-terminal ATPase domain from bacterial ABC class ATPases. This entry also includes MRB1590 from Trypanosoma brucei brucei has a central ATPase domain homologous to this domain.


Pssm-ID: 462914  Cd Length: 282  Bit Score: 512.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 166 NGSQLQQQVELMMDQEEIRQQLVKRDLVAFVANGAILPRKSGVSDLPMNNAIEFKSPKQYEIVMKLSSGKVIKGMGIPKG 245
Cdd:pfam09818   1 DEEALERHVELVEDQEHLRSQLAELGLVAFVANGSILPRESGVSDRPLKGAVPFESPESLEVEIELPNGGTVSGMGIPKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 246 ITLIVGGGYHGKSTLLEALERGVYNHIAGDGREYVITNQDAMKIRAEDGRSIQNVNIQPFIDHLPGEKDTTHFSTENASG 325
Cdd:pfam09818  81 ITLIVGGGFHGKSTLLEALERGVYNHIPGDGREFVVTDPDAVKIRAEDGRSVHGVDISPFINNLPPGKDTTDFSTEDASG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505 326 STSQAANVMEALESQASLLLIDEDTSATNFMIRDGRMQRLIAPEKEPITPFSNKVKALYDDHNVSTILIVGGSGDYFDVA 405
Cdd:pfam09818 161 STSQAANIMEALEAGASLLLIDEDTSATNFMIRDERMQALVSKDKEPITPFVDRVRSLYDDLGVSTILVVGGSGDYLDVA 240
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1516240505 406 DQVLMMDEYVLKDVTQHAKDIAQSDGYQRKVSSHnQFGHIPSR 448
Cdd:pfam09818 241 DTVILMDEYRPSDVTEEAKEIAEELPTGRYEEAS-KFGPPRPR 282
ABC_N pfam20446
ATPase of the ABC class N-terminal; This is the N-terminal domain of various bacterial ...
4-163 5.09e-65

ATPase of the ABC class N-terminal; This is the N-terminal domain of various bacterial predicted ABC class ATPases which shows sequence and structural similarities to the N-terminal domain of MRB1590 (swiss:Q57ZF2) from kinetoplastids, a core protein of the multiprotein mitochondrial RNA binding complex 1 (MRB1) involved in kinetoplastid RNA (kRNA) editing. MRB1590 is a dimer and contains a central ABC ATPase fold (pfam09818) between novel N- and C-terminal regions. The N-terminal domains combine and form a RNA-binding basic pore which involves an arginine patch that has been suggested to act as a chaperone to bind and stabilize ssRNA during kRNA editing processes. N-terminal MRB1590 shows structural similarity to chaperones.


Pssm-ID: 466595  Cd Length: 162  Bit Score: 209.45  E-value: 5.09e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505   4 AQALEQILTSLDGQKYGAYKQIKDLYEFNLFKLRIDHIQADPFAPPSKMSVVIDRQQAKFPDSLLNSELKQRAVSDYLTR 83
Cdd:pfam20446   1 MESLEKFLKSIDGKGYGAYKSLKGEYDLGDFTLFFDRVQGDPFAPPSRVRVRVPGAVQGLPEELKDSKDRRVAAEDFLAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1516240505  84 VFHKQIQSIV--AQDKKVSKIQIDSCGQEILERTAVVIKNHQIEARIEVGLPARGRTILGRIARHTFINVLPQIVENALC 161
Cdd:pfam20446  81 RFAAELRVLVrsSGSGKSGALWIDDPGQEVLERSAVVLTGDGIELRLRVGLPARGRRILGRAAINILLEELPKIVRKALL 160

                  ..
gi 1516240505 162 YR 163
Cdd:pfam20446 161 YL 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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