VIT (vacuolar iron transporter) family protein similar to Schizosaccharomyces pombe Fe(2+)/Mn(2+) transporter Pcl1, which is involved in the transfer of iron and Mn2+ from the cytosol to the vacuole for storage of these metals
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins ...
18-235
4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter.
:
Pssm-ID: 153123 [Multi-domain] Cd Length: 218 Bit Score: 294.88 E-value: 4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins ...
18-235
4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter.
Pssm-ID: 153123 [Multi-domain] Cd Length: 218 Bit Score: 294.88 E-value: 4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins ...
18-235
4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter.
Pssm-ID: 153123 [Multi-domain] Cd Length: 218 Bit Score: 294.88 E-value: 4.60e-102
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_2: This is a family of proteins ...
23-235
1.43e-28
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_2: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter.
Pssm-ID: 153124 [Multi-domain] Cd Length: 234 Bit Score: 107.88 E-value: 1.43e-28
CCC1-related family of proteins; CCC1_like: This protein family includes the proteins related ...
25-235
9.25e-26
CCC1-related family of proteins; CCC1_like: This protein family includes the proteins related to CCC1, a yeast vacuole transmembrane protein responsible for the iron and manganese transport from the cytosol into vacuole. It also includes the proteins similar to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation.
Pssm-ID: 153121 Cd Length: 143 Bit Score: 97.68 E-value: 9.25e-26
Nodulin-21; Nodulin-21: This is a family of proteins that may be unique to certain plants. The ...
25-208
2.26e-13
Nodulin-21; Nodulin-21: This is a family of proteins that may be unique to certain plants. The family member in soybean is found to be nodule-specific and is abundant during nodule development. The proteins of this family thus may play a role in symbiotic nitrogen fixation.
Pssm-ID: 153127 Cd Length: 152 Bit Score: 65.35 E-value: 2.26e-13
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_3: This is a family of proteins ...
25-235
3.36e-13
Nodulin-21 and CCC1-related protein family; Nodulin-21_like_3: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter.
Pssm-ID: 153125 Cd Length: 225 Bit Score: 66.22 E-value: 3.36e-13
CCC1-related domain of ferritin; Ferritin_CCC1_like_C: The proteins of this family contain two ...
25-88
2.27e-06
CCC1-related domain of ferritin; Ferritin_CCC1_like_C: The proteins of this family contain two domains. This is the C-terminal domain that is closely related to the CCC1, a vacuole transmembrane protein functioning as an iron and manganese transporter. The N-terminal domain is similar to ferritin-like diiron-carboxylate proteins, which are involved in a variety of iron ion related functions, such as iron storage and regulation, mono-oxygenation, and reactive radical production. This family may be unique to certain bacteria and archaea.
Pssm-ID: 153122 Cd Length: 149 Bit Score: 45.77 E-value: 2.27e-06
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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of your query sequence and the protein sequences used to curate the domain model,
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The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits
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Domains are color coded according to superfamilies
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Others (non-specific hits) and
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.
To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
or click on the triangles, if present, that represent functional sites (conserved features)
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
(labeled illustration) Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance.
(labeled illustration) Four types of hits can be shown, as available,
for each region on the query sequence:
specific hits meet or exceed a domain-specific e-value threshold
(illustrated example)
and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits
meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the
advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains
Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
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