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Conserved domains on  [gi|1590405239|ref|WP_131691040|]
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gamma-glutamyltransferase [Pseudoalteromonas sp. DL-6]

Protein Classification

gamma-glutamyltransferase family protein( domain architecture ID 10001375)

gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond

CATH:  3.60.20.40
Gene Ontology:  GO:0016787
SCOP:  4000420

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
51-575 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


:

Pssm-ID: 440174  Cd Length: 507  Bit Score: 653.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLN 130
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KhGNAVkwieAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLnPGVMSMPVINE 210
Cdd:COG0405    81 A-GDEI----PVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAA-ERLARDPGAAA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:COG0405   155 IFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQA---AGGLLTLEDLAAYRAEWREPLSGTYRG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSgGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:COG0405   232 YTVYSMPPPSQ-GIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAYAAERA 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLITEK--DQKAQPGNPVDYlsyanddsfELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMV--NGYILNNQLTDFSLS 446
Cdd:COG0405   311 ALIDPDraTPSPRPGDPTGP---------ESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNNRGDDFSLD 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 447 PRkngklVANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPR--TTNRND 524
Cdd:COG0405   382 PG-----HPNALAPGKRPRSTMSPTIVL-KDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRwhHQGLPD 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1590405239 525 YTSLEKGTElEALVPELEERGHDVRVIDLNSG-LHAVEV-KNNRLYGAADPRR 575
Cdd:COG0405   456 TLELEPRFP-PAVIAALRARGHKVEVVPDWSGgAQAILRdPDGVLEGAADPRR 507
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
51-575 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 653.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLN 130
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KhGNAVkwieAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLnPGVMSMPVINE 210
Cdd:COG0405    81 A-GDEI----PVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAA-ERLARDPGAAA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:COG0405   155 IFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQA---AGGLLTLEDLAAYRAEWREPLSGTYRG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSgGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:COG0405   232 YTVYSMPPPSQ-GIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAYAAERA 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLITEK--DQKAQPGNPVDYlsyanddsfELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMV--NGYILNNQLTDFSLS 446
Cdd:COG0405   311 ALIDPDraTPSPRPGDPTGP---------ESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNNRGDDFSLD 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 447 PRkngklVANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPR--TTNRND 524
Cdd:COG0405   382 PG-----HPNALAPGKRPRSTMSPTIVL-KDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRwhHQGLPD 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1590405239 525 YTSLEKGTElEALVPELEERGHDVRVIDLNSG-LHAVEV-KNNRLYGAADPRR 575
Cdd:COG0405   456 TLELEPRFP-PAVIAALRARGHKVEVVPDWSGgAQAILRdPDGVLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
64-577 0e+00

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 547.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  64 RAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLNKHGNAVkwieAVV 143
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDGKGDSKL----SLT 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 144 GGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLnPGVMSMPVINEYFFPNGKVIEVGS 223
Cdd:pfam01019  77 GGLAVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAE-ERLRADPGLRKIFLPTGRVLKAGE 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 224 IKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRVYNVCsMAPPSSGG 303
Cdd:pfam01019 156 LLKQPALAKTLELIAEEGPDAFYRGELAQQLVADLQA---NGGIITAEDLANYRVKIREPLSADYGGYTVY-SPPPSSGG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 304 VAVLQILGLLEHKDMaSIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRAKLIteKDQKAQPg 383
Cdd:pfam01019 232 IALLQILNILEGFDL-SSLLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLI--NPNAAFP- 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 384 npvdyLSYANDDsfelPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMVNGY--ILNNQLTDFSLSPRKNGKLV---ANRV 458
Cdd:pfam01019 308 -----SSYAPED----GGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTgiLLNNEMDDFSTPPGNAFGLDpspANAI 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 459 EAHKRPRSSMSPVMVFNqDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTNRN-DYTSLEKGTElEAL 537
Cdd:pfam01019 379 APGKRPLSSMAPTIVLD-DGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQLpDVLEVEPGFP-EEV 456
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1590405239 538 VPELEERGHDVRVIDLNSGLHAVEV---KNNRLYGAADPRREG 577
Cdd:pfam01019 457 LAELEARGHKVKVVEDSSSVGAIQIvrrTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
51-574 1.08e-144

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 428.42  E-value: 1.08e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLN 130
Cdd:TIGR00066   2 MVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAKATRDMFLD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KHGNAVKWIEAVvGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLNPGVMSMPVINE 210
Cdd:TIGR00066  82 KSGNPLPGKSLT-GGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTLELYEEVLLTTKEDSKD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:TIGR00066 161 IFNPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQK---NGGIMTKKDLAAYDVEIRKPLSGDYRG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSGGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:TIGR00066 238 YQVYTTPPPSSGGIHLLQALNILENFDLSQYGDGSAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEELLDKRYAKELA 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLITEKDQkaqpgNPVDYLSYANDDSFELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMVNGY--ILNNQLTDFSLSPR 448
Cdd:TIGR00066 318 QSIKINKV-----DPKSTIYPGAYQPNEGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTgiLLNNEMDDFSLKPG 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 449 KngklvANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTnrndYTSL 528
Cdd:TIGR00066 393 G-----ANAVEPNKRPLSSMAPTIVL-KDGKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIH----HQWL 462
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1590405239 529 EKGTELEALVPE-----LEERGHDVRV--IDLNSGLHAVEV-KNNRLYGAADPR 574
Cdd:TIGR00066 463 PDELRLEKGFPDdvlqlLKDMGHKVTLkeVFPMGVVQAIRVdPEGWLYGVSDPR 516
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
51-574 4.25e-111

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 344.20  E-value: 4.25e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKaNNKLTSFDGRETAPSNADANLFLN 130
Cdd:PRK09615   51 MVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLRTK-NGNTTAIDFREMAPAKATRDMFLD 129
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KHGNAVKwIEAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLNPGVMSMPVINE 210
Cdd:PRK09615  130 DQGNPDS-KKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKA 208
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKSKiapGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:PRK09615  209 IFWKEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKNG---GLITKEDLAAYKAVERTPISGDYRG 285
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSGGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:PRK09615  286 YQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIA 365
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLIteKDQKAQPGNPVDYLSYAnddSFELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMV--NGYILNNQLTDFSLSPR 448
Cdd:PRK09615  366 DQI--DINKAKPSSEIRPGKLA---PYESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVAgnSGILLNNQMDDFSAKPG 440
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 449 KNG--KLV---ANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTNR- 522
Cdd:PRK09615  441 VPNvyGLVggdANAVGPNKRPLSSMSPTIVV-KDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEATNAPRFHHQw 519
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1590405239 523 -NDYTSLEKGTELEALvPELEERGHDVRVIDLNSGLHAVEV-KNNRLYGAADPR 574
Cdd:PRK09615  520 lPDELRVEKGFSPDTL-KLLEAKGQKVALKEAMGSTQSIMVgPDGELYGASDPR 572
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
51-575 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 653.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLN 130
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KhGNAVkwieAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLnPGVMSMPVINE 210
Cdd:COG0405    81 A-GDEI----PVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAA-ERLARDPGAAA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:COG0405   155 IFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQA---AGGLLTLEDLAAYRAEWREPLSGTYRG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSgGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:COG0405   232 YTVYSMPPPSQ-GIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAYAAERA 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLITEK--DQKAQPGNPVDYlsyanddsfELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMV--NGYILNNQLTDFSLS 446
Cdd:COG0405   311 ALIDPDraTPSPRPGDPTGP---------ESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNNRGDDFSLD 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 447 PRkngklVANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPR--TTNRND 524
Cdd:COG0405   382 PG-----HPNALAPGKRPRSTMSPTIVL-KDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRwhHQGLPD 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1590405239 525 YTSLEKGTElEALVPELEERGHDVRVIDLNSG-LHAVEV-KNNRLYGAADPRR 575
Cdd:COG0405   456 TLELEPRFP-PAVIAALRARGHKVEVVPDWSGgAQAILRdPDGVLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
64-577 0e+00

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 547.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  64 RAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLNKHGNAVkwieAVV 143
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDGKGDSKL----SLT 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 144 GGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLnPGVMSMPVINEYFFPNGKVIEVGS 223
Cdd:pfam01019  77 GGLAVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAE-ERLRADPGLRKIFLPTGRVLKAGE 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 224 IKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRVYNVCsMAPPSSGG 303
Cdd:pfam01019 156 LLKQPALAKTLELIAEEGPDAFYRGELAQQLVADLQA---NGGIITAEDLANYRVKIREPLSADYGGYTVY-SPPPSSGG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 304 VAVLQILGLLEHKDMaSIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRAKLIteKDQKAQPg 383
Cdd:pfam01019 232 IALLQILNILEGFDL-SSLLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLI--NPNAAFP- 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 384 npvdyLSYANDDsfelPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMVNGY--ILNNQLTDFSLSPRKNGKLV---ANRV 458
Cdd:pfam01019 308 -----SSYAPED----GGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTgiLLNNEMDDFSTPPGNAFGLDpspANAI 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 459 EAHKRPRSSMSPVMVFNqDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTNRN-DYTSLEKGTElEAL 537
Cdd:pfam01019 379 APGKRPLSSMAPTIVLD-DGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQLpDVLEVEPGFP-EEV 456
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 1590405239 538 VPELEERGHDVRVIDLNSGLHAVEV---KNNRLYGAADPRREG 577
Cdd:pfam01019 457 LAELEARGHKVKVVEDSSSVGAIQIvrrTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
51-574 1.08e-144

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 428.42  E-value: 1.08e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNADANLFLN 130
Cdd:TIGR00066   2 MVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAKATRDMFLD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KHGNAVKWIEAVvGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLNPGVMSMPVINE 210
Cdd:TIGR00066  82 KSGNPLPGKSLT-GGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTLELYEEVLLTTKEDSKD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:TIGR00066 161 IFNPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQK---NGGIMTKKDLAAYDVEIRKPLSGDYRG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSGGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:TIGR00066 238 YQVYTTPPPSSGGIHLLQALNILENFDLSQYGDGSAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEELLDKRYAKELA 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLITEKDQkaqpgNPVDYLSYANDDSFELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMVNGY--ILNNQLTDFSLSPR 448
Cdd:TIGR00066 318 QSIKINKV-----DPKSTIYPGAYQPNEGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTgiLLNNEMDDFSLKPG 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 449 KngklvANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTnrndYTSL 528
Cdd:TIGR00066 393 G-----ANAVEPNKRPLSSMAPTIVL-KDGKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIH----HQWL 462
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1590405239 529 EKGTELEALVPE-----LEERGHDVRV--IDLNSGLHAVEV-KNNRLYGAADPR 574
Cdd:TIGR00066 463 PDELRLEKGFPDdvlqlLKDMGHKVTLkeVFPMGVVQAIRVdPEGWLYGVSDPR 516
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
51-574 4.25e-111

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 344.20  E-value: 4.25e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  51 MVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKaNNKLTSFDGRETAPSNADANLFLN 130
Cdd:PRK09615   51 MVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLRTK-NGNTTAIDFREMAPAKATRDMFLD 129
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 131 KHGNAVKwIEAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGLLVRQLNPGVMSMPVINE 210
Cdd:PRK09615  130 DQGNPDS-KKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKA 208
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 211 YFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKSKiapGKLSVQDLANYSSKERAPVCIKYRV 290
Cdd:PRK09615  209 IFWKEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKNG---GLITKEDLAAYKAVERTPISGDYRG 285
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 291 YNVCSMAPPSSGGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKYIGDPDFTQVPTQELLDKDYIATRA 370
Cdd:PRK09615  286 YQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIA 365
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 371 KLIteKDQKAQPGNPVDYLSYAnddSFELPSTSHVSIVDSNGNAVSMTSSIEMAFGSTVMV--NGYILNNQLTDFSLSPR 448
Cdd:PRK09615  366 DQI--DINKAKPSSEIRPGKLA---PYESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVAgnSGILLNNQMDDFSAKPG 440
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 449 KNG--KLV---ANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAINLPRTTNR- 522
Cdd:PRK09615  441 VPNvyGLVggdANAVGPNKRPLSSMSPTIVV-KDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEATNAPRFHHQw 519
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1590405239 523 -NDYTSLEKGTELEALvPELEERGHDVRVIDLNSGLHAVEV-KNNRLYGAADPR 574
Cdd:PRK09615  520 lPDELRVEKGFSPDTL-KLLEAKGQKVALKEAMGSTQSIMVgPDGELYGASDPR 572
PLN02198 PLN02198
glutathione gamma-glutamylcysteinyltransferase
34-578 4.16e-73

glutathione gamma-glutamylcysteinyltransferase


Pssm-ID: 177849  Cd Length: 573  Bit Score: 244.60  E-value: 4.16e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  34 EAATGVVQKQLVAGDKYMVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYyNKANNKLTSF 113
Cdd:PLN02198   18 QNAAAQKRQQSIVASHGAVATDDGRCSVIGMNVLREGGNAIDASVAAALCLGVVSPASSGIGGGAFTLI-KLANGEEIAY 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 114 DGRETAPSNADANLFlnkHGNAVKWIEavvGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLHGL 193
Cdd:PLN02198   97 DSRETAPLSATENMY---GGNVELKKK---GALSVGVPGEVAGLFTAWKQHGKLPWKRLVRPAEKLAAEGFKISKYLYMQ 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 194 LVRQlNPGVMSMPVINEYFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKSKiapGKLSVQDL 273
Cdd:PLN02198  171 MNAT-RSDILADKGLSDLFVSNGELKKPGTICHNPKLALTLRLIGEYGPKAFYNGTVGVNLVRDIQKSG---GIITLKDL 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 274 ANYSSKERAPVCIKYRVYNVCSMAPPSSGGVAVLQILGLLEHKDMASiKANSSDAIHYFSQASRIAFADRNKyIGDPDFT 353
Cdd:PLN02198  247 QSYRVKVKEPLSADILGYRVLGMPPPSSGGAAMMLILNILAQYGIPS-GVSGPLGVHRLIEALKHAFAVRMN-LGDPDFV 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 354 QVP--TQELLDKDYIATRAKLITekDQKA-QPGNPVDYLSYANDDSfelpsTSHVSIVDSNGNAVSMTSSIEMAFGSTVM 430
Cdd:PLN02198  325 DVTkvVSDMLSPKFAQDLKSKIN--DNKTfDPKHYGGRWNQIDDHG-----TSHLSIIDSERNAVSMTSTINGYFGALML 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 431 --VNGYILNNQLTDFSLsPRKNGKLV-------ANRVEAHKRPRSSMSPVMVFnQDGSLRLVVGSPGGSRIIDYVAQVVI 501
Cdd:PLN02198  398 spSTGIVLNNEMDDFSI-PMKSGGNLdvpppapANFIRPGKRPLSSMTPTIVL-KDGKVKAAVGASGGANIIAGTTEVYL 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 502 GVLDWDLNAQQAINLPR---------------TTNRNDYTSLEKGTELealvpELEERGHDVRVIDLNSGLHAVEVKNNR 566
Cdd:PLN02198  476 NHFFLKMDPLSSVLAPRiyhqlipnrasyenwTTVYNDHFEIPKATRV-----VLEKKGHVLSPIAGGTIAQFIVQESGE 550
                         570
                  ....*....|....*....
gi 1590405239 567 -------LYGAADPRREGM 578
Cdd:PLN02198  551 nsggrseLVAVSDPRKGGF 569
PLN02180 PLN02180
gamma-glutamyl transpeptidase 4
44-551 5.36e-62

gamma-glutamyl transpeptidase 4


Pssm-ID: 177836  Cd Length: 639  Bit Score: 216.47  E-value: 5.36e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239  44 LVAGDKYMVAAANPYASQAGRAILAQGGSAVDAAIATQLVLTLVEPQSSGIGGGTFMMYYNKANNKLTSFDGRETAPSNA 123
Cdd:PLN02180   77 MVESENGVVAADDARCSEIGASVLRRGGHAVDAAVAITLCIGVVNPMSSGIGGGSFLIVSSQKDSKAEAFDMRETAPLAA 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 124 DANLFLNKHGnavkwiEAVVGGRSVGVPGILHAFASAHKQYGTLPWASLFKPAITLAEQGFEVSPRLhGLLVRQLNPGVM 203
Cdd:PLN02180  157 SKDMYKNDAS------AKSLGALSMGVPGEIAGLYEAWKRYGRLPWKPLFEPAIELARDGFVVHPYL-GKAISSHAAMIL 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 204 SMPVINEYFFPNGKVIEVGSIKKNQPLANLYKDIASKGIDAFYKGDNAKAMVKAVQKskiAPGKLSVQDLANYSSKERAP 283
Cdd:PLN02180  230 KDPGLRSVFSRNGQVLKPGETCYNPELAQSLETISEQGPGAFYNGTIGEKLVKDVKK---AGGIITMDDLRSYEVLVTDA 306
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 284 VCIKYRVYNVCSMAPPSSGGVAVLQILGLLEHKDMASIKANSSDAIHYFSQASRIAFADRNKyIGDPDFTQVPT--QELL 361
Cdd:PLN02180  307 MSVDVMGYTIHGMPPPSGGTLGFSMVIDILDSYSNLYTASGRELGLHRLIEAMKHMFAARMD-LGDPEFVNITNamNQML 385
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 362 DKDYIATRAKLITEkDQKAQPGNPVDYLSYANDDsfelpSTSHVSIVDSNGNAVSMTSSIEMAFGSTVM--VNGYILNNQ 439
Cdd:PLN02180  386 SKAHAEEIQKRIFD-NTTFPPEYYLNRWSQLRDQ-----GTSHFCIVDADRNSVSMTSTVNYGFGAGVLspSTGIVLNNE 459
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590405239 440 LTDFS----LSPRKNGKLVANRVEAHKRPRSSMSPvMVFNQDGSLRLVVGSPGGSRIIDYVAQVVIGVLDWDLNAQQAIN 515
Cdd:PLN02180  460 MDDFStpaeITPDMLPPAPTNFIEPNKRPLSSMTP-LVITKDGEFVAALGGAGGMHIIPAVLQVFLNCFVLNMKPKEAVE 538
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1590405239 516 LPRTTNR--NDYTSLEKGTEL--------EALVPELEERGHDVRVI 551
Cdd:PLN02180  539 SARIYHRliPNVVSYENFTAIngdhigvsEDTKMFLAERGHELKAL 584
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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