|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
2-376 |
1.11e-129 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 379.32 E-value: 1.11e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIA 81
Cdd:cd03817 1 KIAIFTDTYLPQVNGVATSVRNLARALEKRGHEVYVITPSDPGAEDEEEVVRYRSFSIPIRKYHRQHIPFPFKKAVIDRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 82 KHYNLDIIHTQTEFSLGLLGKMIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVLN 161
Cdd:cd03817 81 KELGPDIIHTHTPFSLGKLGLRIARKLKIPIVHTYHTMYEDYLHYIPKGKLLVKAVVRKLVRRFYNHTDAVIAPSEKIKD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 162 LLEGYEVTIPKRVIPTGIPLEKYIRDDITAEevtnlKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENaKIKL 241
Cdd:cd03817 161 TLREYGVKGPIEVIPNGIDLDKFEKPLNTEE-----RRKLGLPPDEPILLYVGRLAKEKNIDFLLRAFAELKKEP-NIKL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 242 IIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDV 321
Cdd:cd03817 235 VIVGDGPEREELKELARELGLADKVIFTGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAASEL 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 322 VTDKMFGTLYYAETDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFY 376
Cdd:cd03817 315 VEDGENGFLFEPNDETLAEKLLHLRENLELLRKLSKNAEISAREFAFAKSVEKLY 369
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
2-347 |
1.27e-51 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 178.12 E-value: 1.27e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVsftDRRVVYRGLISSYKIA 81
Cdd:cd03801 1 KILLLSPELPPPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSL---AALLRARRLLRELRPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 82 KHY-NLDIIHTQTEFSLgLLGKMIGKALRIPVVHTYHTQYEDYVSYIANGKiirpsmvKPLLRGYLKDL---DGVICPSR 157
Cdd:cd03801 78 LRLrKFDVVHAHGLLAA-LLAALLALLLGAPLVVTLHGAEPGRLLLLLAAE-------RRLLARAEALLrraDAVIAVSE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 158 IVLNLLEGYEVTIPKR--VIPTGIPLEKYIRDditaeevtnLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAE 235
Cdd:cd03801 150 ALRDELRALGGIPPEKivVIPNGVDLERFSPP---------LRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRR 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 236 NAKIKLIIVG-DGPYLQDLKhlAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHG 314
Cdd:cd03801 221 GPDVRLVIVGgDGPLRAELE--ELELGLGDRVRFLGFVPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATD 298
|
330 340 350
....*....|....*....|....*....|...
gi 1622294796 315 NPYLDDVVTDKmfGTLYYAETDLTDAIIDAILK 347
Cdd:cd03801 299 VGGLPEVVEDG--EGGLVVPPDDVEALADALLR 329
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
2-312 |
5.68e-50 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 173.63 E-value: 5.68e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIA 81
Cdd:cd03814 1 RIALVTDTYHPQVNGVVRTLERLVDHLRRRGHEVRVVAPGPFDEAESAEGRVVSVPSFPLPFYPEYRLALPLPRRVRRLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 82 KHYNLDIIHTQTEFSLGLLGKMIGKALRIPVVHTYHTQYEDYVSYIAngkiirPSMVKPLLRGYLKDL----DGVICPSR 157
Cdd:cd03814 81 KEFQPDIIHIATPGPLGLAALRAARRLGLPVVTSYHTDFPEYLSYYT------LGPLSWLAWAYLRWFhnpfDTTLVPSP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 158 IVLNLLEGYEVTiPKRVIPTGIPLEKY---IRDDItaeevtnLKAELGiAGDETMLLSLSRISYEKNIQAIINQMPAiLA 234
Cdd:cd03814 155 SIARELEGHGFE-RVRLWPRGVDTELFhpsRRDAA-------LRRRLG-PPGRPLLLYVGRLAPEKNLEALLDADLP-LA 224
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622294796 235 ENAKIKLIIVGDGPYLQDLKHlamqleVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd03814 225 ASPPVRLVVVGDGPARAELEA------RGPDVIFTGFLTGEELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVA 296
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
9-378 |
1.38e-35 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 134.40 E-value: 1.38e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 9 TYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEdPTIIRLPSVpFVSFTdrrVVYRGLISSYKIAKHYNLDI 88
Cdd:cd03819 5 TPALEIGGAETYILDLARALAERGHRVLVVTAGGPLLPRLR-QIGIGLPGL-KVPLL---RALLGNVRLARLIRRERIDL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 89 IHTQTeFSLGLLGKMIGKALRIPVVHTYHtqyedyVSYIANgKIIRPSMVKPLLRGylkdlDGVICPSRIVLNLLEGYEV 168
Cdd:cd03819 80 IHAHS-RAPAWLGWLASRLTGVPLVTTVH------GSYLAT-YHPKDFALAVRARG-----DRVIAVSELVRDHLIEALG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 169 TIPKR--VIPTGIPLEKYirddiTAEEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIInQMPAILAENAKIKLIIVGD 246
Cdd:cd03819 147 VDPERirVIPNGVDTDRF-----PPEAEAEERAQLGLPEGKPVVGYVGRLSPEKGWLLLV-DAAAELKDEPDFRLLVAGD 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 247 GPYLQDLKHLAMQLEVDKHVTFTGMvsHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKM 326
Cdd:cd03819 221 GPERDEIRRLVERLGLRDRVTFTGF--REDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGR 298
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1622294796 327 FGTLYYAETD--LTDAIIDAILKTPvmdkrlLAKKRYEISAQhfGKSIYTFYLD 378
Cdd:cd03819 299 TGLLVPPGDAeaLADAIRAAKLLPE------AREKLQAAAAL--TEAVRELLLR 344
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
16-182 |
1.18e-32 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 121.49 E-value: 1.18e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 16 GVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEF 95
Cdd:pfam13439 2 GVERYVLELARALARRGHEVTVVTPGGPGPLAEEVVRVVRVPRVPLPLPPRLLRSLAFLRRLRRLLRRERPDVVHAHSPF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 96 SLGLLGKMIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPsMVKPLLRGYLKDLDGVICPSRIVLNLLEGYEVTIPKR-- 173
Cdd:pfam13439 82 PLGLAALAARLRLGIPLVVTYHGLFPDYKRLGARLSPLRR-LLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKir 160
|
....*....
gi 1622294796 174 VIPTGIPLE 182
Cdd:pfam13439 161 VIPNGVDLE 169
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
16-365 |
2.43e-31 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 122.85 E-value: 2.43e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 16 GVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYK-IAKHYNLDIIHTQTE 94
Cdd:cd03811 13 GAERVLLNLANALDKRGYDVTLVLLRDEGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILKLKrILKRAKPDVVISFLG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 95 FSLGLLGKMigKALRIPVVHTYHTQYEDYVSYiangkiirPSMVKPLLRGYLKdLDGVICPSRIVLNLLEGYEVTIPKR- 173
Cdd:cd03811 93 FATYIVAKL--AAARSKVIAWIHSSLSKLYYL--------KKKLLLKLKLYKK-ADKIVCVSKGIKEDLIRLGPSPPEKi 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 174 -VIPTGIplekyirdDITAEEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQD 252
Cdd:cd03811 162 eVIYNPI--------DIDRIRALAKEPILNEPEDGPVILAVGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 253 LKHLAMQLEVDKHVTFTGMVShdKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYY 332
Cdd:cd03811 234 LEKLAKELGLAERVIFLGFQS--NPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGENGLLVP 311
|
330 340 350
....*....|....*....|....*....|...
gi 1622294796 333 AETDLTDAIIDAILKTPVMDKRLLAKKRYEISA 365
Cdd:cd03811 312 DGDAAALAGILAALLQKKLDAALRERLAKAQEA 344
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
9-379 |
9.47e-30 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 119.02 E-value: 9.47e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 9 TYFPQVS--GVATSIRTLKEELEKEGHEVYIFTTTD-------RDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISS-- 77
Cdd:cd03798 6 NIYPNANspGRGIFVRRQVRALSRRGVDVEVLAPAPwgpaaarLLRKLLGEAVPPRDGRRLLPLKPRLRLLAPLRAPSla 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 78 --YKIAKHYNLDIIHTQTEFSLGLLGKMIGKALRIPVVHTYHTqyedyvSYIanGKIIRPSMVKPLLRGYLKDLDGVICP 155
Cdd:cd03798 86 klLKRRRRGPPDLIHAHFAYPAGFAAALLARLYGVPYVVTEHG------SDI--NVFPPRSLLRKLLRWALRRAARVIAV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 156 SRIVLNLLEGYEVtIPKR--VIPTGIPLEKYirdditaeevTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAIL 233
Cdd:cd03798 158 SKALAEELVALGV-PRDRvdVIPNGVDPARF----------QPEDRGLGLPLDAFVILFVGRLIPRKGIDLLLEAFARLA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 234 AENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAH 313
Cdd:cd03798 227 KARPDVVLLIVGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVAT 306
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622294796 314 GNPYLDDVVTDKMFGTLyYAETD---LTDAIIDAILKTPVMDKRLLAKKRY--EISAQHFGKSIYTFYLDT 379
Cdd:cd03798 307 DVGGIPEVVGDPETGLL-VPPGDadaLAAALRRALAEPYLRELGEAARARVaeRFSWVKAADRIAAAYRDV 376
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
206-367 |
8.65e-26 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 102.35 E-value: 8.65e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 206 DETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACD 285
Cdd:pfam00534 1 KKKIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 286 FFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETDltDAIIDAILKtpVMDKRLLAKKRYEISA 365
Cdd:pfam00534 81 VFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNA--EALAEAIDK--LLEDEELRERLGENAR 156
|
..
gi 1622294796 366 QH 367
Cdd:pfam00534 157 KR 158
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
21-316 |
3.54e-25 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 106.56 E-value: 3.54e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 21 IRTLKEELEKEGHEVYIFT--TTDRDVKRFEDPT---IIRLPSVPFVsFTDRRVVYR-------GLISSYKiAKHYNLDI 88
Cdd:cd03800 27 VLELARALAELGYQVDIFTrrISPADPEVVEIAPgarVIRVPAGPPE-YLPKEELWPyleefadGLLRFIA-REGGRYDL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 89 IHTQteFSL-GLLGKMIGKALRIPVVHTYHT-------------QYEDYVSYIANGKIIRPSmvkpllrgylkdlDGVI- 153
Cdd:cd03800 105 IHSH--YWDsGLVGALLARRLGVPLVHTFHSlgrvkyrhlgaqdTYHPSLRITAEEQILEAA-------------DRVIa 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 154 -CPSRIV--LNLLEGYEVTIpkRVIPTGIPLEKYIRDDitaeEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMP 230
Cdd:cd03800 170 sTPQEADelISLYGADPSRI--NVVPPGVDLERFFPVD----RAEARRARLLLPPDKPVVLALGRLDPRKGIDTLVRAFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 231 AILAENAKIKLIIVG---DGPYLQD---LKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESL 304
Cdd:cd03800 244 QLPELRELANLVLVGgpsDDPLSMDreeLAELAEELGLIDRVRFPGRVSRDDLPELYRAADVFVVPSLYEPFGLTAIEAM 323
|
330
....*....|....
gi 1622294796 305 ASGTPIIA--HGNP 316
Cdd:cd03800 324 ACGTPVVAtaVGGL 337
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
2-347 |
3.24e-24 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 103.58 E-value: 3.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFT---------TTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYR 72
Cdd:cd03794 1 KILLISQYYPPPKGAAAARVYELAKELVRRGHEVTVLTpspnyplgrIFAGATETKDGIRVIRVKLGPIKKNGLIRRLLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 73 GLISSYKIAKHYNL-----DIIHTQTE-FSLGLLGKMIGKALRIPVVHTYHTQYEDyvSYIANGKIIRPSMVKPLLRGY- 145
Cdd:cd03794 81 YLSFALAALLKLLVreerpDVIIAYSPpITLGLAALLLKKLRGAPFILDVRDLWPE--SLIALGVLKKGSLLKLLKKLEr 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 146 --LKDLDGVICPSRIVLNLLEGYEVTIPK-RVIPTGIPLEKYIRDDItaeevtNLKAELGIAGDETMLLSLSRISYEKNI 222
Cdd:cd03794 159 klYRLADAIIVLSPGLKEYLLRKGVPKEKiIVIPNWADLEEFKPPPK------DELRKKLGLDDKFVVVYAGNIGKAQGL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 223 QAIINQMpAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKhVTFTGMVSHDKVALYYKACDF-FISASTSETQGLTY- 300
Cdd:cd03794 233 ETLLEAA-ERLKRRPDIRFLFVGDGDEKERLKELAKARGLDN-VTFLGRVPKEEVPELLSAADVgLVPLKDNPANRGSSp 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1622294796 301 ---IESLASGTPIIAHGNPYLDDVVTDKMFGtlYYAETDLTDAIIDAILK 347
Cdd:cd03794 311 sklFEYMAAGKPILASDDGGSDLAVEINGCG--LVVEPGDPEALADAILE 358
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
2-374 |
5.08e-23 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 99.66 E-value: 5.08e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVP-FVSFTDRRVVYRGLISSYKI 80
Cdd:cd03795 1 KVLHVFKFYYPDIGGIEQVIYDLAEGLKKKGIEVDVLCFSKEKETPEKEENGIRIHRVKsFLNVASTPFSPSYIKRFKKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 81 AKHYnlDIIHTQTEFSLGLLGKMIGKALRiPVVHTYHtqyedyvSYIANGKIIRPsMVKPLLRGYLKDLDGVICPSRIVL 160
Cdd:cd03795 81 AKEY--DIIHYHFPNPLADLLLFFSGAKK-PVVVHWH-------SDIVKQKKLLK-LYKPLMTRFLRRADRIIATSPNYV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 161 N---LLEGYEVtiPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIagdetmLLSLSRISYEKNIQAIINQMPAIlaena 237
Cdd:cd03795 150 EtspTLREFKN--KVRVIPLGIDKNVYNIPRVDFENIKREKKGKKI------FLFIGRLVYYKGLDYLIEAAQYL----- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 238 KIKLIIVGDGPYLQDLKHLAMQLEVDKhVTFTGMVSHDKVALYYKACDFFI--SASTSETQGLTYIESLASGTPIIA--- 312
Cdd:cd03795 217 NYPIVIGGEGPLKPDLEAQIELNLLDN-VKFLGRVDDEEKVIYLHLCDVFVfpSVLRSEAFGIVLLEAMMCGKPVIStni 295
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622294796 313 -HGNPYlddVVTDKMFGTLYYAET--DLTDAiIDAILKTPVMDKRL--LAKKRYEisaQHFGKSIYT 374
Cdd:cd03795 296 gTGVPY---VNNNGETGLVVPPKDpdALAEA-IDKLLSDEELRESYgeNAKKRFE---ELFTAEKMK 355
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
2-363 |
9.18e-22 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 97.09 E-value: 9.18e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTD-TYFPQVSGVATSIRTLKEELEKEGHEVYIFTTtDRDV-KRFEDPTIIRLPSVPF-----VSFT---DRRVvy 71
Cdd:PLN02871 60 RIALFVEpSPFSYVSGYKNRFQNFIRYLREMGDEVLVVTT-DEGVpQEFHGAKVIGSWSFPCpfyqkVPLSlalSPRI-- 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 72 rglissYKIAKHYNLDIIHTQtefSLGLL---GKMIGKALRIPVVHTYHTQYEDYV-SYIANGkiirpsMVKP---LLRG 144
Cdd:PLN02871 137 ------ISEVARFKPDLIHAS---SPGIMvfgALFYAKLLCVPLVMSYHTHVPVYIpRYTFSW------LVKPmwdIIRF 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 145 YLKDLDGVICPSRIVLNLLEGYEVTIPKR--VIPTGIPLEKY---IRDDITAEEVTNlkaelGIAGDETMLlSLSRISYE 219
Cdd:PLN02871 202 LHRAADLTLVTSPALGKELEAAGVTAANRirVWNKGVDSESFhprFRSEEMRARLSG-----GEPEKPLIV-YVGRLGAE 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 220 KNIQAIINqmpaILAENAKIKLIIVGDGPYLQDL-KHLAmqlevDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGL 298
Cdd:PLN02871 276 KNLDFLKR----VMERLPGARLAFVGDGPYREELeKMFA-----GTPTVFTGMLQGDELSQAYASGDVFVMPSESETLGF 346
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622294796 299 TYIESLASGTPIIAHGNPYLDDVVTDKMFG--TLYYAETDLTDAI--IDAILKTPVMDKRLLAKKRYEI 363
Cdd:PLN02871 347 VVLEAMASGVPVVAARAGGIPDIIPPDQEGktGFLYTPGDVDDCVekLETLLADPELRERMGAAAREEV 415
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
13-364 |
3.28e-21 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 94.28 E-value: 3.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 13 QVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEDptIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQ 92
Cdd:cd03812 10 NVGGIETFLMNLYRKLDKSKIEFDFLATSDDKGEYDEE--LEELGGKIFYIPPKKKNIIKYFIKLLKLIKKEKYDIVHVH 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 93 TEFSLGLLGKMIGKA-LRIPVVHTYHTQYEDyvsyIANGKIIRPSMVKPLLRGYlkdlDGVICPSRIVLNLLEGYEVTIP 171
Cdd:cd03812 88 GSSSNGIILLLAAKAgVPVRIAHSHNTKDSS----IKLRKIRKNVLKKLIERLS----TKYLACSEDAGEWLFGEVENGK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 172 KRVIPTGIPLEKYIRDDitaeEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQ 251
Cdd:cd03812 160 FKVIPNGIDIEKYKFNK----EKRRKRRKLLILEDKLVLGHVGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 252 DLKHLAMQLEVDKHVTFTGMVShdKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMF---- 327
Cdd:cd03812 236 KIKEKVKELGLEDKVIFLGFRN--DVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTITKECDITNNVEflpl 313
|
330 340 350
....*....|....*....|....*....|....*....
gi 1622294796 328 --GTLYYAETDLTDAIIDAILKTPVMDKRLLAKKRYEIS 364
Cdd:cd03812 314 neTPSTWAEKILKLIKRKRRINKEINKEKKELGYDDESL 352
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
2-312 |
4.50e-21 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 93.93 E-value: 4.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIR-TLKEELEKEGHEVYIFTTTDRD--VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSY 78
Cdd:cd03823 1 KILLVNSLYPPQRVGGAEISVhDLAEALVAEGHEVAVLTAGVGPpgQATVARSVVRYRRAPDETLPLALKRRGYELFETY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 79 --KIAKHYNL-------DIIHTQ--TEFSLGLLgKMIgKALRIPVVHTYHtqyeDYvsyiaNGKIIRPSMVKpllrgylK 147
Cdd:cd03823 81 npGLRRLLARlledfrpDVVHTHnlSGLGASLL-DAA-RDLGIPVVHTLH----DY-----WLLCPRQFLFK-------K 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 148 DLDGVICPSRIVLNLLE--GYEvTIPKRVIPTGIPLEKYiRDDITAEEVTNLKaeLGIAGdetmllslsRISYEKNIQAI 225
Cdd:cd03823 143 GGDAVLAPSRFTANLHEanGLF-SARISVIPNAVEPDLA-PPPRRRPGTERLR--FGYIG---------RLTEEKGIDLL 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 226 INQMPAILAENakIKLIIVGDGPyLQDLKhlamQLEVDKHVTFTGMVSHDKVALYYKACDFFISAST-SETQGLTYIESL 304
Cdd:cd03823 210 VEAFKRLPRED--IELVIAGHGP-LSDER----QIEGGRRIAFLGRVPTDDIKDFYEKIDVLVVPSIwPEPFGLVVREAI 282
|
....*...
gi 1622294796 305 ASGTPIIA 312
Cdd:cd03823 283 AAGLPVIA 290
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
210-347 |
1.25e-20 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 87.57 E-value: 1.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 210 LLSLSRIS-YEKNIQAIINQMPAILAENAKIKLIIVGDGPyLQDLKHLAmqLEVDKHVTFTGMVshDKVALYYKACDFFI 288
Cdd:pfam13692 4 ILFVGRLHpNVKGVDYLLEAVPLLRKRDNDVRLVIVGDGP-EEELEELA--AGLEDRVIFTGFV--EDLAELLAAADVFV 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1622294796 289 SASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKmfgTLYYAETDLTDAIIDAILK 347
Cdd:pfam13692 79 LPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELVDGE---NGLLVPPGDPEALAEAILR 134
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
14-376 |
1.46e-20 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 92.77 E-value: 1.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 14 VSGVATSIRTLKEELEKEGHEVYIFTTTDRDVkRFEDptiIRLPSVPFV-----SFTDRRVVYRgLIssyKIAKHYNLDI 88
Cdd:cd03807 11 VGGAETMLLRLLEHMDKSRFEHVVISLTGDGV-LGEE---LLAAGVPVVclglsSGKDPGVLLR-LA---KLIRKRNPDV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 89 IHTQ---TEFSLGLLGKMIGKalrIPVVHTYHTQYEDYVSyiaNGKIIRpsmVKPLLRGYLKDldgVICPSRIVLNLLEg 165
Cdd:cd03807 83 VHTWmyhADLIGGLAAKLAGG---VKVIWSVRSSNIPQRL---TRLVRK---LCLLLSKFSPA---TVANSSAVAEFHQ- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 166 yEVTIPK---RVIPTGIPLEKYirdDITAEEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLI 242
Cdd:cd03807 150 -EQGYAKnkiVVIYNGIDLFKL---SPDDASRARARRRLGLAEDRRVIGIVGRLHPVKDHSDLLRAAALLVETHPDLRLL 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 243 IVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHdkVALYYKACDFFISASTSETQGLTYIESLASGTPIIAH---GNPYLd 319
Cdd:cd03807 226 LVGRGPERPNLERLLLELGLEDRVHLLGERSD--VPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATdvgGAAEL- 302
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622294796 320 dvvTDKMFGTLYYAET--DLTDAIIDAIL---KTPVMDKRLLAKKRYEISAQHFGKSIYTFY 376
Cdd:cd03807 303 ---VDDGTGFLVPAGDpqALADAIRALLEdpeKRARLGRAARERIANEFSIDAMVRRYETLY 361
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
1-312 |
2.74e-19 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 88.95 E-value: 2.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 1 MRIGLftdTYFPQVSG---VATSirtLKEELEKEGHEVYiFTTTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISS 77
Cdd:cd04962 1 MKIGI---VCYPSYGGsgvVATE---LGLELAERGHEVH-FISSAIPFRLNLYSGNIFFHEVEVPNYPLFEYPPYTLALA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 78 YKIA---KHYNLDIIHTQTEF---SLGLL-GKMIGKalRIPVVHTYHTQYEDYVSYiangkiiRPSMvKPLLRGYLKDLD 150
Cdd:cd04962 74 SKIVevaKEHKLDVLHAHYAIphaSCAYLaREILGE--KIPIVTTLHGTDITLVGY-------DPSL-QPAVRFSINKSD 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 151 GVICPSRIVLN-LLEGYEVTIPKRVIPTGIPLEKYIRDDITAeevtnLKAELGIAGDETMLLSLSRISYEKNIQAIInQM 229
Cdd:cd04962 144 RVTAVSSSLRQeTYELFDVDKDIEVIHNFIDEDVFKRKPAGA-----LKRRLLAPPDEKVVIHVSNFRPVKRIDDVV-RV 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 230 PAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGmvSHDKVALYYKACDFFISASTSETQGLTYIESLASGTP 309
Cdd:cd04962 218 FARVRRKIPAKLLLVGDGPERVPAEELARELGVEDRVLFLG--KQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVP 295
|
...
gi 1622294796 310 IIA 312
Cdd:cd04962 296 VVS 298
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
2-355 |
8.55e-19 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 87.42 E-value: 8.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTD----RDVKRFEDPTIIRL--PSVPFVSFTDRRVVYRGLI 75
Cdd:cd03821 1 KILHVTPSISPKAGGPVKVVLRLAAALAALGHEVTIVSTGDgyesLVVEENGRYIPPQDgfASIPLLRQGAGRTDFSPGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 76 SSYKIAKHYNLDIIHTQTEFSLGLL-GKMIGKALRIPVVHTYHTqyeDYVSYIANGKIIRPSMVKPL-LRGYLKDLDGVI 153
Cdd:cd03821 81 PNWLRRNLREYDVVHIHGVWTYTSLaACKLARRRGIPYVVSPHG---MLDPWALQQKHWKKRIALHLiERRNLNNAALVH 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 154 CPSRIVLNLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVtnlkaelGIAGDETMLLSLSRISYEKNIQAIINQMPAIL 233
Cdd:cd03821 158 FTSEQEADELRRFGLEPPIAVIPNGVDIPEFDPGLRDRRKH-------NGLEDRRIILFLGRIHPKKGLDLLIRAARKLA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 234 AENAKIKLIIVG-DGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd03821 231 EQGRDWHLVIAGpDDGAYPAFLQLQSSLGLGDRVTFTGPLYGEAKWALYASADLFVLPSYSENFGNVVAEALACGLPVVI 310
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1622294796 313 HGNPYLDDVVTDKMFGTLYYAETDLTDAIIdAILKTPVMDKRL 355
Cdd:cd03821 311 TDKCGLSELVEAGCGVVVDPNVSSLAEALA-EALRDPADRKRL 352
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
3-324 |
2.77e-18 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 83.61 E-value: 2.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 3 IGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFEdptiirlpsvpfvsftdrrvvyrglissyKIAK 82
Cdd:cd01635 1 ILLVTGEYPPLRGGLELHVRALARALAALGHEVTVLALLLLALRRIL-----------------------------KKLL 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 83 HYNLDIIHTQTEFSLGLLGKMIGKALRIPVVHTYHTqyeDYVSYIANGKIIRPSMVKPLLRGYLKdldgvicpsrivlnl 162
Cdd:cd01635 52 ELKPDVVHAHSPHAAALAALLAARLLGIPIVVTVHG---PDSLESTRSELLALARLLVSLPLADK--------------- 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 163 legyevtipkrviptgiplekyirdditaeevtnlkaelgiagdetmlLSLSRISYEKNIQAIINQMPAILAENAKIKLI 242
Cdd:cd01635 114 ------------------------------------------------VSVGRLVPEKGIDLLLEALALLKARLPDLVLV 145
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 243 IVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHD-KVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDV 321
Cdd:cd01635 146 LVGGGGEREEEEALAAALGLLERVVIIGGLVDDeVLELLLAAADVFVLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEF 225
|
...
gi 1622294796 322 VTD 324
Cdd:cd01635 226 VVD 228
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
15-312 |
7.42e-17 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 81.64 E-value: 7.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 15 SGVATSIRTLKEELEK-EGHEVYIFTttdrdvkrFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQT 93
Cdd:cd03809 14 TGIGRYTRELLKALAKnDPDESVLAV--------PPLPGELLRLLREYPELSLGVIKIKLWRELALLRWLQILLPKKDKP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 94 EFSLGLLGKMIGKALRIPVVHTYHT-QYEDYVSYIANGKIIRPSMVKPLLrgyLKDLDGVICPSRIVLN-LLEGYEVTIP 171
Cdd:cd03809 86 DLLHSPHNTAPLLLKGCPQVVTIHDlIPLRYPEFFPKRFRLYYRLLLPIS---LRRADAIITVSEATRDdIIKFYGVPPE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 172 K-RVIPTGIPLEKYIRDdiTAEEVTNLKAElgiagDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVG-DGPY 249
Cdd:cd03809 163 KiVVIPLGVDPSFFPPE--SAAVLIAKYLL-----PEPYFLYVGTLEPRKNHERLLKAFALLKKQGGDLKLVIVGgKGWE 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622294796 250 LQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd03809 236 DEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIA 298
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
13-372 |
7.40e-16 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 78.41 E-value: 7.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 13 QVSGVATSIRTLKEELEKEGHEVYIFTTTDRDVKRFED-----PTIIRLPSVPFVSFTDrrvvYRGLISSYKIAKHYNLD 87
Cdd:cd03808 8 VDGGFQSFRLPLIKALVKKGYEVHVIAPDGDKLSDELKelgvkVIDIPILRRGINPLKD----LKALFKLYKLLKKEKPD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 88 IIHTQTEFSlGLLG----KMIGKALRIPVVHTYHTQYedyvsyiANGKIIRpSMVKPLLRGYLKDLDGVICPSR------ 157
Cdd:cd03808 84 IVHCHTPKP-GILGrlaaRLAGVPKVIYTVHGLGFVF-------TEGKLLR-LLYLLLEKLALLFTDKVIFVNEddrdla 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 158 IVLNLLEGYEVTIpkrVIPTGIPLEKYIRDDITAEEvtnlkaelgiagDETMLLSLSRISYEKNIQAIINQMpAILAENA 237
Cdd:cd03808 155 IKKGIIKKKKTVL---IPGSGVDLDRFQYSPESLPS------------EKVVFLFVARLLKDKGIDELIEAA-KILKKKG 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 238 -KIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHdkVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNP 316
Cdd:cd03808 219 pNVRFLLVGDGELENPSEILIEKLGLEGRIEFLGFRSD--VPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVP 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1622294796 317 YLDDVVTDKMFGTLY--YAETDLTDAIIdAILKTPvmDKRL-LAKKRYEISAQHFGKSI 372
Cdd:cd03808 297 GCRELVIDGVNGFLVppGDVEALADAIE-KLIEDP--ELRKeMGEAARKRVEEKFDEEK 352
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
175-312 |
3.80e-15 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 76.33 E-value: 3.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 175 IPTGIPLEKYIRDDitaEEVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLK 254
Cdd:cd04951 159 VYNGIDLNKFKKDI---NVRLKIRNKLNLKNDEFVILNVGRLTEAKDYPNLLLAISELILSKNDFKLLIAGDGPLRNELE 235
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1622294796 255 HLAMQLEVDKHVTFTGmvSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd04951 236 RLICNLNLVDRVILLG--QISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVA 291
|
|
| GT4_PIG-A-like |
cd03796 |
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ... |
2-307 |
3.88e-14 |
|
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.
Pssm-ID: 340827 [Multi-domain] Cd Length: 398 Bit Score: 73.81 E-value: 3.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTttdrdvKRFEDPTIIR----------LPSVPFVsftdRRVVY 71
Cdd:cd03796 1 RICMVSDFFYPNLGGVETHIYQLSQCLIKRGHKVIVIT------HAYGNRVGVRyltnglkvyyLPFKVFY----NQSTL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 72 RGLISSYKIAKHY----NLDIIHTQTEFS-LGLLGKMIGKALRIPVVHTYHTQYE--DYVSYIANgkiirpsmvkPLLRG 144
Cdd:cd03796 71 PTLFSTFPLLRNIlireRIQIVHGHQAFSsLAHEALFHARTLGLKTVFTDHSLFGfaDASSILTN----------KLLRF 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 145 YLKDLDGVICPSRIvlnlleGYEVTI------PKR--VIPTGIPLEKYIRDDITAEEvtnlkaelgiagDETMLLSLSRI 216
Cdd:cd03796 141 SLADIDHVICVSHT------SKENTVlrasldPRIvsVIPNAVDSSDFTPDPSKPDP------------NKITIVVISRL 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 217 SYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQ 296
Cdd:cd03796 203 VYRKGIDLLVGIIPRICKKHPNVRFIIGGDGPKRIELEEMREKYQLQDRVELLGAVPHEEVRDVLVQGHIFLNTSLTEAF 282
|
330
....*....|.
gi 1622294796 297 GLTYIESLASG 307
Cdd:cd03796 283 CIAIVEAASCG 293
|
|
| Glyco_trans_4_4 |
pfam13579 |
Glycosyl transferase 4-like domain; |
15-178 |
1.59e-13 |
|
Glycosyl transferase 4-like domain;
Pssm-ID: 433325 [Multi-domain] Cd Length: 158 Bit Score: 68.20 E-value: 1.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 15 SGVATSIRTLKEELEKEGHEVYIFT---TTDRDVKRFEDPTIIRLPSVPFVSFTDRRVVYRGLissYKIAKHYNLDIIHT 91
Cdd:pfam13579 1 GGIGVYVLELARALAALGHEVRVVTpggPPGRPELVGDGVRVHRLPVPPRPSPLADLAALRRL---RRLLRAERPDVVHA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 92 QTeFSLGLLGKMIGKALRIPVVHTYHTQYEDYvsyianGKIIRPSMVKPLLRGYLKDLDGVICPSRIVLNLLEGYEVTIP 171
Cdd:pfam13579 78 HS-PTAGLAARLARRRRGVPLVVTVHGLALDY------GSGWKRRLARALERRLLRRADAVVVVSEAEAELLRALGVPAA 150
|
....*...
gi 1622294796 172 K-RVIPTG 178
Cdd:pfam13579 151 RvVVVPNG 158
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
277-368 |
1.14e-12 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 64.63 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 277 VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAET--DLTDAIIDaILKTPVMDKR 354
Cdd:COG0438 14 LEALLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDpeALAEAILR-LLEDPELRRR 92
|
90
....*....|....
gi 1622294796 355 lLAKKRYEISAQHF 368
Cdd:COG0438 93 -LGEAARERAEERF 105
|
|
| PRK15484 |
PRK15484 |
lipopolysaccharide N-acetylglucosaminyltransferase; |
152-366 |
2.22e-12 |
|
lipopolysaccharide N-acetylglucosaminyltransferase;
Pssm-ID: 185381 [Multi-domain] Cd Length: 380 Bit Score: 68.28 E-value: 2.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 152 VICPSRIVLNLLEGYEVTIPKRVIPTGIPLEKYIRDDitaeeVTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPA 231
Cdd:PRK15484 143 IIVPSQFLKKFYEERLPNADISIVPNGFCLETYQSNP-----QPNLRQQLNISPDETVLLYAGRISPDKGILLLMQAFEK 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 232 ILAENAKIKLIIVGD---------GPYLQDLKHLAMQLEVDKHVtfTGMVSHDKVALYYKACDFFISAST-SETQGLTYI 301
Cdd:PRK15484 218 LATAHSNLKLVVVGDptasskgekAAYQKKVLEAAKRIGDRCIM--LGGQPPEKMHNYYPLADLVVVPSQvEEAFCMVAV 295
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 302 ESLASGTPIIAHGNPYLDDVVTDKMFGtLYYAETDLTDAIIDAILKTpvmdkrLLAKKRYEISAQ 366
Cdd:PRK15484 296 EAMAAGKPVLASTKGGITEFVLEGITG-YHLAEPMTSDSIISDINRT------LADPELTQIAEQ 353
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
23-312 |
4.08e-12 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 67.26 E-value: 4.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 23 TLKEELEKEGHEVYIFTTTDRDVKRF----EDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTqteFSLG 98
Cdd:cd03820 21 NLANHLAKKGYDVTIISLDSAEKPPFyeldDNIKIKNLGDRKYSHFKLLLKYFKKVRRLRKYLKNNKPDVVIS---FRTS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 99 LLGKMIGKALRIPVVHTYHTqyedyvSYIANGKIIRPSMVKpllRGYLKDLDGVICPSRIVLnlLEGYEVTIPK-RVIPT 177
Cdd:cd03820 98 LLTFLALIGLKSKLIVWEHN------NYEAYNKGLRRLLLR---RLLYKRADKIVVLTEADK--LKKYKQPNSNvVVIPN 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 178 GIPLEKYirdditaEEVTNLKAELgiagdetmLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLA 257
Cdd:cd03820 167 PLSFPSE-------EPSTNLKSKR--------ILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLI 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 258 MQLEVDKHVTFTGMVSHdkVALYYKACDFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd03820 232 DKLGLEDRVKLLGPTKN--IAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIIS 284
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
195-373 |
1.41e-11 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 65.40 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 195 TNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMvsH 274
Cdd:cd04949 148 QLDTAESNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGYGEEREKLKKLIEELHLEDNVFLKGY--H 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 275 DKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPY-LDDVVTDKMFGTL--YYAETDLTDAIIDAILKTPVM 351
Cdd:cd04949 226 SNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKYgPSELIEDGENGYLieKNNIDALADKIIELLNDPEKL 305
|
170 180
....*....|....*....|..
gi 1622294796 352 DKrlLAKKRYEISAQHFGKSIY 373
Cdd:cd04949 306 QQ--FSEESYKIAEKYSTENVM 325
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
86-312 |
4.61e-10 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 61.20 E-value: 4.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 86 LDIIHTQTEFSLGLLGKMIGKALRIPVVHTYHTQY--EDYVsyiangKIIRPSMVKPLLRGYLKDLDGVICP-----SRI 158
Cdd:cd03813 174 ADLYHSVSTGYAGLLGALARHRRGIPFLLTEHGIYtrERKI------EILQSTWIMGYIKKLWIRFFERLGKlayqqADK 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 159 VLNLLEG---YEVTI---PKR--VIPTGIPLEKYirDDITAEEVTNLKAELGIAGdetmllslsRISYEKNIQAIINQMP 230
Cdd:cd03813 248 IISLYEGnrrRQIRLgadPDKtrVIPNGIDIQRF--APAREERPEKEPPVVGLVG---------RVVPIKDVKTFIRAFK 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 231 AILAENAKIKLIIVG----DGPYLQDLKHLAMQLEVDKHVTFTGMVShdkVALYYKACDFFISASTSETQGLTYIESLAS 306
Cdd:cd03813 317 LVRRAMPDAEGWLIGpedeDPEYAQECKRLVASLGLENKVKFLGFQN---IKEYYPKLGLLVLTSISEGQPLVILEAMAS 393
|
....*.
gi 1622294796 307 GTPIIA 312
Cdd:cd03813 394 GVPVVA 399
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
23-370 |
7.94e-10 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 59.99 E-value: 7.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 23 TLKEELEKEGHEVYIFTTTDRDVKRFEDPTIIRLPSVPFVSFTDrrVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK 102
Cdd:cd03802 26 ALTEGLVRRGHEVTLFAPGDSHTSAPLVAVIPRALRLDPIPQES--KLAELLEALEVQLRASDFDVIHNHSYDWLPPFAP 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 103 MIGKalriPVVHTYHTQYEDYVSYIAngkiirpSMVKPLLRGYLKDLDGVICPsrivlnllegyevTIPKR-VIPTGIPL 181
Cdd:cd03802 104 LIGT----PFVTTLHGPSIPPSLAIY-------AAEPPVNYVSISDAQRAATP-------------PIDYLtVVHNGLDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 182 EKYIRDDitaeevtnlkaelgiaGDETMLLSLSRISYEKNIQAiinqmpAI-LAENAKIKLIIVGDGPYlQDLKHLAMQL 260
Cdd:cd03802 160 ADYRFQP----------------DPEDYLAFLGRIAPEKGLED------AIrVARRAGLPLKIAGKVRD-EDYFYYLQEP 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 261 EVDKHVTFTGMVSHD-KVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLyyaeTDLTD 339
Cdd:cd03802 217 LPGPRIEFIGEVGHDeKQELLGGARALLFPINWDEPFGLVMIEAMACGTPVIAYRRGGLPEVIQHGETGFL----VDSVE 292
|
330 340 350
....*....|....*....|....*....|....
gi 1622294796 340 AIIDAILKTPVMDK---RLLAKKRYeiSAQHFGK 370
Cdd:cd03802 293 EMAEAIANIDRIDRaacRRYAEDRF--SAARMAD 324
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
170-378 |
9.87e-10 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 60.04 E-value: 9.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 170 IPKRVIPTGIPLEKYIRDDITAeevtnLKAELGIAGDETMLLSLSRiSYE---KNIQAIINQMpAILAENAKIKLIIVG- 245
Cdd:cd03825 161 LPVVVIPNGIDTEIFAPVDKAK-----ARKRLGIPQDKKVILFGAE-SVTkprKGFDELIEAL-KLLATKDDLLLVVFGk 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 246 DGPYLQDLKHLAMQLEVDKHVTftgmvshdKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDK 325
Cdd:cd03825 234 NDPQIVILPFDIISLGYIDDDE--------QLVDIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTGGSPEIVQHG 305
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 326 MFGTLY--YAETDLTDAiIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLD 378
Cdd:cd03825 306 VTGYLVppGDVQALAEA-IEWLLANPKERESLGERARALAENHFDQRVQAQRYLE 359
|
|
| GT4_mannosyltransferase-like |
cd03822 |
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ... |
2-347 |
1.68e-09 |
|
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.
Pssm-ID: 340849 [Multi-domain] Cd Length: 370 Bit Score: 59.32 E-value: 1.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 2 RIGLFTdTYFPQVSGVATSIRTLKEELEKEGHEVY--IFTTTDRDVKRFEDPTIIRLPSVPFVSFtdrrvvYRGLISSYK 79
Cdd:cd03822 1 KIAVLG-TLPPRKCGIATYTDDLVEGLRKGGPVVIvvIVSPQDEILKDDDFEVPNEIKSWNSNEY------FRLLDHLNF 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 80 IAkhynLDIIHTQTEFSLGLlGKMIGKAL------RIPVVHTYHTqyedYVSYIANGKIIRPSMVKPLLRgylkdLDGVI 153
Cdd:cd03822 74 KK----PDVVHIQHEFGIFG-GKYGLYALglllhlRIPVITTLHT----VLDLSDPGKQALKVLFRIATL-----SERVV 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 154 CPSRIVLNLLEGYEVtIPKR---VIPTGIPlekyirdDITAEEVTNLKAELGIAGdETMLLSLSRISYEKNIQAIINQMP 230
Cdd:cd03822 140 VMAPISRFLLVRIKL-IPAVnieVIPHGVP-------EVPQDPTTALKRLLLPEG-KKVILTFGFIGPGKGLEILLEALP 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 231 AILAENAKIKLIIVG-DGPYLQD------LKHLAMQLEVDKHVTF-TGMVSHDKVALYYKACDFFISA--STSETQGLTY 300
Cdd:cd03822 211 ELKAEFPDVRLVIAGeLHPSLARyegeryRKAAIEELGLQDHVDFhNNFLPEEEVPRYISAADVVVLPylNTEQSSSGTL 290
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1622294796 301 IESLASGTPIIAHGNPYLDDVVTDkmfGTLYYAETDLTDAIIDAILK 347
Cdd:cd03822 291 SYAIACGKPVISTPLRHAEELLAD---GRGVLVPFDDPSAIAEAILR 334
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
211-372 |
2.25e-09 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 58.84 E-value: 2.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 211 LSLSRISYEKNIQAII---NQMPAilaenakiKLIIVGDGPYLQDLKHLAmqlevDKHVTFTGMVSHDKVALYYKACDFF 287
Cdd:cd03804 203 LTASRLVPYKRIDLAVeafNELPK--------RLVVIGDGPDLDRLRAMA-----SPNVEFLGYQPDEVLKELLSKARAF 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 288 ISASTsETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETdlTDAIIDAIL----KTPVMDKRLLAKKRYEI 363
Cdd:cd03804 270 VFAAE-EDFGIVPVEAQACGTPVIAFGKGGALETVRPGPTGILFGEQT--VESLKAAVEefeqNFDRFKPQAIRANAERF 346
|
....*....
gi 1622294796 364 SAQHFGKSI 372
Cdd:cd03804 347 SRARFRQEI 355
|
|
| GT4_AmsK-like |
cd04946 |
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ... |
134-312 |
1.51e-08 |
|
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.
Pssm-ID: 340854 [Multi-domain] Cd Length: 401 Bit Score: 56.31 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 134 RPSMVKPLLRGYLKDLDGVICPSRIVLNLLEGyevTIP-----KRVIPTGIPlekyirddiTAEEVTNLKAELGIAgdet 208
Cdd:cd04946 163 YGSYYLPLREYLVSYLDAVFLISKEGKDYLQK---CYPaykekIFVSRLGVS---------DKEQYSKVKKEGDLR---- 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 209 mLLSLSRISYEKNIQAIIN--QMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYK--AC 284
Cdd:cd04946 227 -LVSCSSIVPVKRIDLIIEtlNSLCVAHPSICISWTHIGGGPLKERLEKLAENKLENVKVNFTGEVSNKEVKQLYKenDV 305
|
170 180
....*....|....*....|....*...
gi 1622294796 285 DFFISASTSETQGLTYIESLASGTPIIA 312
Cdd:cd04946 306 DVFVNVSESEGIPVSIMEAISFGIPVIA 333
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
86-368 |
5.69e-08 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 54.38 E-value: 5.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 86 LDIIHTQTEFSlGLLGKMIGKALRIPVVHTYHTqYEDYVS--YIANGKIIRpsMVKPLLRGYL-KDLDGVICPSRivlnl 162
Cdd:cd05844 82 PALVHAHFGRD-GVYALPLARALGVPLVVTFHG-FDITTSraWLAASPGWP--SQFQRHRRALqRPAALFVAVSG----- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 163 legyevTIPKRVIPTGIPLEKYIRDDITAEevTNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLI 242
Cdd:cd05844 153 ------FIRDRLLARGLPAERIHVHYIGID--PAKFAPRDPAERAPTILFVGRLVEKKGCDVLIEAFRRLAARHPTARLV 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 243 IVGDGPYLQDLKHLAMQLEvdkHVTFTGMVSHDKVALYYKACDFFISAST------SETQGLTYIESLASGTPIIAHGNP 316
Cdd:cd05844 225 IAGDGPLRPALQALAAALG---RVRFLGALPHAEVQDWMRRAEIFCLPSVtaasgdSEGLGIVLLEAAACGVPVVSSRHG 301
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 317 YLDDVVTDKMFGtLYYAETD---LTDAiIDAILKTPVMDKRLLAKKRyEISAQHF 368
Cdd:cd05844 302 GIPEAILDGETG-FLVPEGDvdaLADA-LQALLADRALADRMGGAAR-AFVCEQF 353
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
32-330 |
9.26e-07 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 50.53 E-value: 9.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 32 GHEVYIFTTTD-RDVKRFEDPTIIRLPSVPFVSftdrrvVYRGLISsykiAKHYnlDIIHTQtefsLGLLGKMIGKALRI 110
Cdd:cd03799 28 GHEVDIYAVNPgDLVKRHPDVEKYNVPSLNLLY------AIVGLNK----KGAY--DIIHCQ----FGPLGALGALLRRL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 111 PV-------------VHTYHTQY--EDYVSYIANGKIIRPSMvkpllRGYLKDLDGVICPsrivlnllegyevtiPKRVI 175
Cdd:cd03799 92 KVlkgklvtsfrgydISMYVILEgnKVYPQLFAQGDLFLPNC-----ELFKHRLIALGCD---------------EKKII 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 176 PT--GIPLEKYirdditaeevtNLKAELGIAGDETMLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDL 253
Cdd:cd03799 152 VHrsGIDCNKF-----------RFKPRYLPLDGKIRILTVGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 254 KHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQG------LTYIESLASGTPIIAHGNPYLDDVVTDKMF 327
Cdd:cd03799 221 QQLIQELNIGDCVKLLGWKPQEEIIEILDEADIFIAPSVTAADGdqdgppNTLKEAMAMGLPVISTEHGGIPELVEDGVS 300
|
...
gi 1622294796 328 GTL 330
Cdd:cd03799 301 GFL 303
|
|
| GT4_ALG11-like |
cd03806 |
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related ... |
192-371 |
1.33e-06 |
|
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
Pssm-ID: 340835 [Multi-domain] Cd Length: 419 Bit Score: 50.30 E-value: 1.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 192 EEVTNLKAELGiaGDETMLLSLSRISYEKN----IQAI---INQMPAILAENakIKLIIVG------DGPYLQDLKHLAM 258
Cdd:cd03806 224 EELTKLPIDEK--TRENQILSIAQFRPEKNhplqLRAFaelLKRLPESIRSN--PKLVLIGscrneeDKERVEALKLLAK 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 259 QLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAH--GNPYLDDVVTDKMFGTLYYAET- 335
Cdd:cd03806 300 ELILEDSVEFVVDAPYEELKELLSTASIGLHTMWNEHFGIGVVEYMAAGLIPLAHasAGPLLDIVVPWDGGPTGFLASTp 379
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1622294796 336 ---DLTDAIIDAILKTPVMDKRLLAKKRYEI-SAQHFGKS 371
Cdd:cd03806 380 eeyAEAIEKILTLSEEERLQRREAARSSAERfSDEEFERD 419
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
170-365 |
1.09e-05 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 47.72 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 170 IPKRVIP---TGIPLEKYIRDDITAEEVTNLKAElgiAGDETMLL-SLSRISYEKNIQAIINQMPAILAENAKIKLIIVG 245
Cdd:PRK15179 479 VDERRIPvvyNGLAPLKSVQDDACTAMMAQFDAR---TSDARFTVgTVMRVDDNKRPFLWVEAAQRFAASHPKVRFIMVG 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 246 DGPYLQDLKHLAMQLEVDKHVTFTGMVSHdkVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDK 325
Cdd:PRK15179 556 GGPLLESVREFAQRLGMGERILFTGLSRR--VGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEG 633
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1622294796 326 MFGTLYYAET----DLTDA---IIDAILKTPVMDK--RLLAKKRYEISA 365
Cdd:PRK15179 634 VTGLTLPADTvtapDVAEAlarIHDMCAADPGIARkaADWASARFSLNQ 682
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
197-345 |
1.09e-05 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 47.56 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 197 LKAELGIAGDET--MLLSLSRISYEKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQlevdkhvtftgmvSH 274
Cdd:cd03791 282 LQKELGLPVDPDapLFGFVGRLTEQKGVDLILDALPELLEEGGQLVVLGSGDPEYEQAFRELAER-------------YP 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 275 DKVALY-----------YKACDFFISASTSETQGLTYIESLASGTPIIAH---GnpyLDDVVTD----KMFGTLY----Y 332
Cdd:cd03791 349 GKVAVVigfdealahriYAGADFFLMPSRFEPCGLVQMYAMRYGTLPIVRrtgG---LADTVFDydpeTGEGTGFvfedY 425
|
170
....*....|...
gi 1622294796 333 AETDLTDAIIDAI 345
Cdd:cd03791 426 DAEALLAALRRAL 438
|
|
| PLN02949 |
PLN02949 |
transferase, transferring glycosyl groups |
234-365 |
4.08e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215511 [Multi-domain] Cd Length: 463 Bit Score: 45.88 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 234 AENAKIKLIIVG------DGPYLQDLKHLAMQLEVDKHVTFTGMVSHDKVALYYKACDFFISASTSETQGLTYIESLASG 307
Cdd:PLN02949 299 ADVPRPKLQFVGscrnkeDEERLQKLKDRAKELGLDGDVEFHKNVSYRDLVRLLGGAVAGLHSMIDEHFGISVVEYMAAG 378
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622294796 308 TPIIAH--GNPYLDDVVTDKMFGTLYYAET--DLTDAIIDAIlktpvmdkRLLAKKRYEISA 365
Cdd:PLN02949 379 AVPIAHnsAGPKMDIVLDEDGQQTGFLATTveEYADAILEVL--------RMRETERLEIAA 432
|
|
| PHA01633 |
PHA01633 |
putative glycosyl transferase group 1 |
259-378 |
1.05e-04 |
|
putative glycosyl transferase group 1
Pssm-ID: 107050 [Multi-domain] Cd Length: 335 Bit Score: 44.20 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 259 QLEVDKHVTFT---GMVSHDKVALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVT------------ 323
Cdd:PHA01633 196 QLEVPANVHFVaefGHNSREYIFAFYGAMDFTIVPSGTEGFGMPVLESMAMGTPVIHQLMPPLDEFTSwqwnlliksskv 275
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 324 ----DKMFGTLY-YAETDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLD 378
Cdd:PHA01633 276 eeyyDKEHGQKWkIHKFQIEDMANAIILAFELQDREERSMKLKELAKKYDIRNLYTRFLE 335
|
|
| GT4_ExpC-like |
cd03818 |
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ... |
230-346 |
7.72e-04 |
|
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).
Pssm-ID: 340845 [Multi-domain] Cd Length: 396 Bit Score: 41.58 E-value: 7.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 230 PAILAENAKIKLIIVGDG--------PYLQDLK-HLAMQLEVD-KHVTFTGMVSHDKVALYYKACDFFISastsetqgLT 299
Cdd:cd03818 237 PRIQARRPDARVVVVGGDgvsygsppPDGGSWKqKMLAELGVDlERVHFVGKVPYDQYVRLLQLSDAHVY--------LT 308
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1622294796 300 Y--------IESLASGTPIIAHGNPYLDDVVTDKMFGTLyyAETDLTDAIIDAIL 346
Cdd:cd03818 309 YpfvlswslLEAMACGCPVIGSDTAPVREVIRDGRNGLL--VDFFDPDALAAAVL 361
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
181-315 |
3.70e-03 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 39.49 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622294796 181 LEKYIRD------DITAEEVTNLKAELG---IAGDETMLLSLSRISYEKNIQAIINQMpAIL----AENAKIKLIIVG-- 245
Cdd:cd03805 176 LAKNPPEvlypcvDTDSFDSTSEDPDPGdliAKSNKKFFLSINRFERKKNIALAIEAF-AKLkqklPEFENVRLVIAGgy 254
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622294796 246 DG------PYLQDLKHLAMQLE-VDKHVTFTGMVS-HDKVALYyKACDFFISASTSETQGLTYIESLASGTPIIAHGN 315
Cdd:cd03805 255 DPrvaenvEYLEELQRLAEELLnVEDQVLFLRSISdSQKEQLL-SSALALLYTPSNEHFGIVPLEAMYAGKPVIACNS 331
|
|
| |
