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Conserved domains on  [gi|1682442989|ref|WP_139157645|]
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MULTISPECIES: recombinase family protein, partial [Enterobacteriaceae]

Protein Classification

recombinase family protein( domain architecture ID 10132964)

recombinase family protein is a serine recombinase that catalyzes the site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme

CATH:  3.40.50.1390
Gene Ontology:  GO:0015074|GO:0000150|GO:0003677|GO:0006310
PubMed:  11972771|16077726|9348666|21645851|26104451
SCOP:  3000065

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
 3-79 1.38e-27

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


:

Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 96.39  E-value: 1.38e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1682442989   3 LFGYARVSTSQQSLDLQVRALKDAGvKANRIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQL 79
Cdd:cd03768     1 VIGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEI 76
 
Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
 3-79 1.38e-27

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 96.39  E-value: 1.38e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1682442989   3 LFGYARVSTSQQSLDLQVRALKDAGvKANRIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQL 79
Cdd:cd03768     1 VIGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEI 76
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
 1-79 8.12e-22

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 86.62  E-value: 8.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   1 MRLFGYARVSTSQQ---SLDLQVRALKD----AGVKANRIFTDKA-SGSSTDREGLDLLRMKVEEG--DVILVKKLDRLG 70
Cdd:COG1961     2 MRAAGYARVSTDDQeglSLERQREALRAyaekAGWEIVRIYVDEGvSGTSKDRPGLQRLLADLRAGkfDTLVVWKLDRLG 81


                  ....*....
gi 1682442989  71 RDTADMIQL 79
Cdd:COG1961    82 RNLADLLEL 90
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
 4-79 3.88e-18

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 72.69  E-value: 3.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   4 FGYARVSTSQQ--SLDLQVRALKDAGVKANRI--FTDK-ASGSSTDREGLDLLRMKVEE--GDVILVKKLDRLGRDTADM 76
Cdd:pfam00239   2 IGYARVSTEDQddSLERQLEALRAYAACNGKIveFEDKgVSGRKLDRPGLQRLLALLRAgkGDVLVVYKLDRLGRSLRDL 81


                  ...
gi 1682442989  77 IQL 79
Cdd:pfam00239  82 LTL 84
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
 4-79 6.93e-18

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 72.27  E-value: 6.93e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989    4 FGYARVSTSQQ---SLDLQVRALKDA----GVKANRIFTDKA-SGSSTDREGLDLLRMKVEEGD--VILVKKLDRLGRDT 73
Cdd:smart00857   2 AGYARVSTDDQadgSLERQLEALRAYaernGWEVVRIYEDEGvSGKKADRPGLQRLLADLRAGDidVLVVYKLDRLGRSL 81


                   ....*.
gi 1682442989   74 ADMIQL 79
Cdd:smart00857  82 RDLLAL 87
recomb_XisF NF041201
fdxN element excision recombinase XisF;
5-79 4.63e-14

fdxN element excision recombinase XisF;


Pssm-ID: 469105 [Multi-domain]  Cd Length: 463  Bit Score: 64.98  E-value: 4.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   5 GYARVSTSQQ-----SLDLQVRALKDAGvkANRIFTDKASGSSTDREGLD-LLRMkVEEGDV--ILVKKLDRLGRDTADM 76
Cdd:NF041201    3 GYARVSTREQaddghALEQQIARLKKAG--ASEIFFDIESGRSDKRKGFNqLLKL-VKSGKVteIIITRIDRLTRSVVTI 79


                  ...
gi 1682442989  77 IQL 79
Cdd:NF041201   80 YKA 82
transpos_IS607 NF033518
IS607 family transposase;
5-71 2.34e-07

IS607 family transposase;


Pssm-ID: 468054 [Multi-domain]  Cd Length: 187  Bit Score: 45.32  E-value: 2.34e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1682442989   5 GYARVSTSQQSLDL--QVRALKD----AGVKANRIFTDKASGSSTDREGLDLLRMKVEEGDV--ILVKKLDRLGR 71
Cdd:NF033518   58 IYARVSSADQKDDLerQVARLTQyataKGWQVDEVVTDIGSGLNEKRKGLLKLLDDILNGEVsrVVVEHKDRLTR 132
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
3-71 6.66e-05

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 38.93  E-value: 6.66e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1682442989   3 LFGYARVSTSQQSLDLQ----VRALKDAGVKANRIFTDKASG--SSTDREGLDLLRmKVEEGDVILVKKLDRLGR 71
Cdd:PRK13413    2 IYAYIRVSTDKQTVENQrfeiTNFAEKNNLTIDKWIEETISGtkSYKDRKLGKLLK-KMRKGDILIVSELSRLGR 75
 
Name Accession Description Interval E-value
SR_ResInv cd03768
Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members ...
 3-79 1.38e-27

Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.


Pssm-ID: 239737 [Multi-domain]  Cd Length: 126  Bit Score: 96.39  E-value: 1.38e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1682442989   3 LFGYARVSTSQQSLDLQVRALKDAGvKANRIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQL 79
Cdd:cd03768     1 VIGYARVSTDDQSLERQLEALKAAG-ECDKIFEEKGSGGKKERPELQKLLEDLREGDTLVVTKLDRLGRSTKDLLEI 76
SpoIVCA COG1961
Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and ...
 1-79 8.12e-22

Site-specific DNA recombinase SpoIVCA/DNA invertase PinE [Replication, recombination and repair];


Pssm-ID: 441564 [Multi-domain]  Cd Length: 388  Bit Score: 86.62  E-value: 8.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   1 MRLFGYARVSTSQQ---SLDLQVRALKD----AGVKANRIFTDKA-SGSSTDREGLDLLRMKVEEG--DVILVKKLDRLG 70
Cdd:COG1961     2 MRAAGYARVSTDDQeglSLERQREALRAyaekAGWEIVRIYVDEGvSGTSKDRPGLQRLLADLRAGkfDTLVVWKLDRLG 81


                  ....*....
gi 1682442989  71 RDTADMIQL 79
Cdd:COG1961    82 RNLADLLEL 90
Resolvase pfam00239
Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) ...
 4-79 3.88e-18

Resolvase, N terminal domain; The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.


Pssm-ID: 425548 [Multi-domain]  Cd Length: 144  Bit Score: 72.69  E-value: 3.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   4 FGYARVSTSQQ--SLDLQVRALKDAGVKANRI--FTDK-ASGSSTDREGLDLLRMKVEE--GDVILVKKLDRLGRDTADM 76
Cdd:pfam00239   2 IGYARVSTEDQddSLERQLEALRAYAACNGKIveFEDKgVSGRKLDRPGLQRLLALLRAgkGDVLVVYKLDRLGRSLRDL 81


                  ...
gi 1682442989  77 IQL 79
Cdd:pfam00239  82 LTL 84
Resolvase smart00857
Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the ...
 4-79 6.93e-18

Resolvase, N terminal domain; The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.


Pssm-ID: 214861 [Multi-domain]  Cd Length: 148  Bit Score: 72.27  E-value: 6.93e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989    4 FGYARVSTSQQ---SLDLQVRALKDA----GVKANRIFTDKA-SGSSTDREGLDLLRMKVEEGD--VILVKKLDRLGRDT 73
Cdd:smart00857   2 AGYARVSTDDQadgSLERQLEALRAYaernGWEVVRIYEDEGvSGKKADRPGLQRLLADLRAGDidVLVVYKLDRLGRSL 81


                   ....*.
gi 1682442989   74 ADMIQL 79
Cdd:smart00857  82 RDLLAL 87
recomb_XisF NF041201
fdxN element excision recombinase XisF;
5-79 4.63e-14

fdxN element excision recombinase XisF;


Pssm-ID: 469105 [Multi-domain]  Cd Length: 463  Bit Score: 64.98  E-value: 4.63e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   5 GYARVSTSQQ-----SLDLQVRALKDAGvkANRIFTDKASGSSTDREGLD-LLRMkVEEGDV--ILVKKLDRLGRDTADM 76
Cdd:NF041201    3 GYARVSTREQaddghALEQQIARLKKAG--ASEIFFDIESGRSDKRKGFNqLLKL-VKSGKVteIIITRIDRLTRSVVTI 79


                  ...
gi 1682442989  77 IQL 79
Cdd:NF041201   80 YKA 82
Ser_Recombinase cd00338
Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or ...
 6-79 9.93e-13

Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.


Pssm-ID: 238206 [Multi-domain]  Cd Length: 137  Bit Score: 58.81  E-value: 9.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   6 YARVSTSQQ----SLDLQVRALKDA----GVKANRIFTDKASGSST--DREGLDLLRMKVEEG--DVILVKKLDRLGRDT 73
Cdd:cd00338     2 YARVSTDKQeqgdSLERQREALREYaarnGLEVVGEYEDAGSSATSlvDRPGLQRLLADVKAGkiDVVLVEKLDRLSRNL 81


                  ....*.
gi 1682442989  74 ADMIQL 79
Cdd:cd00338    82 VDLLEL 87
SR_Res_par cd03767
Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; ...
 5-75 1.14e-07

Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subgroup is composed of proteins similar to the E. coli resolvase found in the par region of the RP4 plasmid, which encodes a highly efficient partitioning system. This protein is part of a complex stabilization system involved in the resolution of plasmid dimers during cell division. Similar to Tn3 and other resolvases, members of this family may contain a C-terminal DNA binding domain.


Pssm-ID: 239736 [Multi-domain]  Cd Length: 146  Bit Score: 45.78  E-value: 1.14e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1682442989   5 GYARVSTSQQSLDLQVRAL----KDAGVKANRIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKLDRLGRDTAD 75
Cdd:cd03767     3 AYLRASTDEQDATRAKESLeafaTERGFYIAGFYVENASGAKLDRPELFRLLDDAQSGDVLLVEQIDRLSRLPLD 77
transpos_IS607 NF033518
IS607 family transposase;
5-71 2.34e-07

IS607 family transposase;


Pssm-ID: 468054 [Multi-domain]  Cd Length: 187  Bit Score: 45.32  E-value: 2.34e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1682442989   5 GYARVSTSQQSLDL--QVRALKD----AGVKANRIFTDKASGSSTDREGLDLLRMKVEEGDV--ILVKKLDRLGR 71
Cdd:NF033518   58 IYARVSSADQKDDLerQVARLTQyataKGWQVDEVVTDIGSGLNEKRKGLLKLLDDILNGEVsrVVVEHKDRLTR 132
SR_IS607_transposase_like cd03769
Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members ...
 5-71 1.77e-06

Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.


Pssm-ID: 239738  Cd Length: 134  Bit Score: 42.25  E-value: 1.77e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1682442989   5 GYARVSTSQQSLDL--QVRALKD---AGVKANRIFTDKASGSSTDREGLDLLRMKVEEGDV--ILVKKLDRLGR 71
Cdd:cd03769     3 LYARVSSHDQKDDLerQIERLEAyatAQGWIVEVIKDIGSGLNEKRKGLLKLLEDVLAGKVerVVITYKDRLAR 76
COG2452 COG2452
Predicted site-specific integrase-resolvase [Mobilome: prophages, transposons];
2-78 4.77e-06

Predicted site-specific integrase-resolvase [Mobilome: prophages, transposons];


Pssm-ID: 441988 [Multi-domain]  Cd Length: 178  Bit Score: 41.90  E-value: 4.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1682442989   2 RLFGYARVSTSQQSLDL--QVRALKDAGVKAN---RIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKlDRLGRDTADM 76
Cdd:COG2452    49 RTVIYARVSSADQKDDLerQVERLEEYATAKGyqdEVIKDVGSGLNYKRKGLLKLLERIEVERVVVEHK-DRLARFGFEL 127


                  ..
gi 1682442989  77 IQ 78
Cdd:COG2452   128 LE 129
SR_TndX_transposase cd03770
Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of ...
 24-72 2.74e-05

Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. TndX mediates the excision and circularization of the conjugative transposon Tn5397 from Clostridium difficile. TnpX is responsible for the movement of the nonconjugative chloramphenicol resistance elements of the Tn4451/3 family. Mobile genetic elements such as transposons are important vehicles for the transmission of virulence and antibiotic resistance in many microorganisms.


Pssm-ID: 239739 [Multi-domain]  Cd Length: 140  Bit Score: 39.27  E-value: 2.74e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1682442989  24 KDAGVKANRIFTDKA-SGSSTDREGLDLLRMKVEEG--DVILVKKLDRLGRD 72
Cdd:cd03770    32 KENGLENIRHYIDDGfSGTTFDRPGFNRMIEDIEAGkiDIVIVKDMSRLGRN 83
mpi PRK13413
master DNA invertase Mpi family serine-type recombinase;
3-71 6.66e-05

master DNA invertase Mpi family serine-type recombinase;


Pssm-ID: 184041 [Multi-domain]  Cd Length: 200  Bit Score: 38.93  E-value: 6.66e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1682442989   3 LFGYARVSTSQQSLDLQ----VRALKDAGVKANRIFTDKASG--SSTDREGLDLLRmKVEEGDVILVKKLDRLGR 71
Cdd:PRK13413    2 IYAYIRVSTDKQTVENQrfeiTNFAEKNNLTIDKWIEETISGtkSYKDRKLGKLLK-KMRKGDILIVSELSRLGR 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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