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Conserved domains on  [gi|1690610313|ref|WP_139412414|]
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TrbC/VirB2 family protein [Bartonella mastomydis]

Protein Classification

TrbC/VirB2 family protein( domain architecture ID 10522976)

TrbC/VirB2 family protein may function a major pilus subunit; similar to type IV secretion system protein PtlA, which is a component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 27-113 1.29e-19

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


:

Pssm-ID: 398559  Cd Length: 98  Bit Score: 76.49  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  27 LTTVLMLFIAFLALSDPAFAEGFG-KVETALQKIVDTLNGPIAISIATIAVAGIGLAWIAGYVEMRKAFFVCVGIGIIFG 105
Cdd:pfam04956  11 LALALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGPIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFG 90


                  ....*...
gi 1690610313 106 ASQIVSML 113
Cdd:pfam04956  91 ASTIVSTL 98
 
Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 27-113 1.29e-19

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 76.49  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  27 LTTVLMLFIAFLALSDPAFAEGFG-KVETALQKIVDTLNGPIAISIATIAVAGIGLAWIAGYVEMRKAFFVCVGIGIIFG 105
Cdd:pfam04956  11 LALALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGPIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFG 90


                  ....*...
gi 1690610313 106 ASQIVSML 113
Cdd:pfam04956  91 ASTIVSTL 98
VirB2 COG3838
Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and ...
 18-113 3.57e-17

Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443049  Cd Length: 109  Bit Score: 70.75  E-value: 3.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  18 TLSNTQKKWLTTVLMLFIAFLALSDPAFAEGFG-KVETALQKIVDTLNGPIAISIATIAVAGIGLAWIAGYVE--MRKAF 94
Cdd:COG3838     2 KFLSMPLRRRLLLLALAALLLLLASPAFAAGSGmPWEGPLQQIVNSLTGPVAKAIAVIAIIVAGLMLAFGELNggFRRAI 81

                          90
                  ....*....|....*....
gi 1690610313  95 FVCVGIGIIFGASQIVSML 113
Cdd:COG3838    82 QVVLGISIAFGASSIVLSF 100
PRK13871 PRK13871
conjugal transfer protein TrbC; Provisional
 35-115 2.75e-05

conjugal transfer protein TrbC; Provisional


Pssm-ID: 172391  Cd Length: 135  Bit Score: 40.64  E-value: 2.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  35 IAFLALSDPAFAEGFGKV---ETALQKIVDTLNGPIA--ISIATIAVAGiGLAWIAGYVE--MRKAFFVCVGIGIIFGAS 107
Cdd:PRK13871   17 VSFIGLADPAFASSGGGSlpwESPLQQIQQSITGPVAgfIALAAVAIAG-AMLIFGGELNdfARRLCYVALVGGVLLGAT 95


                  ....*...
gi 1690610313 108 QIVSMLKA 115
Cdd:PRK13871   96 QIVALFGA 103
 
Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 27-113 1.29e-19

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 76.49  E-value: 1.29e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  27 LTTVLMLFIAFLALSDPAFAEGFG-KVETALQKIVDTLNGPIAISIATIAVAGIGLAWIAGYVEMRKAFFVCVGIGIIFG 105
Cdd:pfam04956  11 LALALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGPIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFG 90


                  ....*...
gi 1690610313 106 ASQIVSML 113
Cdd:pfam04956  91 ASTIVSTL 98
VirB2 COG3838
Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and ...
 18-113 3.57e-17

Type IV secretory pathway, VirB2 component (pilin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443049  Cd Length: 109  Bit Score: 70.75  E-value: 3.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  18 TLSNTQKKWLTTVLMLFIAFLALSDPAFAEGFG-KVETALQKIVDTLNGPIAISIATIAVAGIGLAWIAGYVE--MRKAF 94
Cdd:COG3838     2 KFLSMPLRRRLLLLALAALLLLLASPAFAAGSGmPWEGPLQQIVNSLTGPVAKAIAVIAIIVAGLMLAFGELNggFRRAI 81

                          90
                  ....*....|....*....
gi 1690610313  95 FVCVGIGIIFGASQIVSML 113
Cdd:COG3838    82 QVVLGISIAFGASSIVLSF 100
PRK13871 PRK13871
conjugal transfer protein TrbC; Provisional
 35-115 2.75e-05

conjugal transfer protein TrbC; Provisional


Pssm-ID: 172391  Cd Length: 135  Bit Score: 40.64  E-value: 2.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1690610313  35 IAFLALSDPAFAEGFGKV---ETALQKIVDTLNGPIA--ISIATIAVAGiGLAWIAGYVE--MRKAFFVCVGIGIIFGAS 107
Cdd:PRK13871   17 VSFIGLADPAFASSGGGSlpwESPLQQIQQSITGPVAgfIALAAVAIAG-AMLIFGGELNdfARRLCYVALVGGVLLGAT 95


                  ....*...
gi 1690610313 108 QIVSMLKA 115
Cdd:PRK13871   96 QIVALFGA 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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