|
Name |
Accession |
Description |
Interval |
E-value |
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
15-550 |
2.09e-156 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 458.47 E-value: 2.09e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:COG0028 2 KMTGADALVEALEAEGVETVFGVPGGAILPLYDALRRqSGIRHILVRHEQGAAFMADGYARATGKPGVCLVTSGPGATNL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGarrKGMLHQLdDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVW 173
Cdd:COG0028 82 VTGLADAYMDSVPVLAITGQVPTSLIG---RGAFQEV-DQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 174 LEIPQNVLLDPIMVPPVEDALAEAADNP-PRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTP 252
Cdd:COG0028 158 LDIPKDVQAAEAEEEPAPPELRGYRPRPaPDPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 253 GGNGAFPWNHELSLQAW--IEDRYMTDVLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESNRP-GLGIR 328
Cdd:COG0028 238 MGKGAFPEDHPLYLGMLgmHGTPAANEALAEADLVLAVGARFDDrVTGNWDEFAPDAKIIHIDIDPAEIGKNYPvDLPIV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 329 ADAGQALAALDEALQPGRAAAPDWHgatpESLVQESLAKVRARLESQDLGKELKFMADIREAVPADMQTFWDMTIAAYWG 408
Cdd:COG0028 318 GDAKAVLAALLEALEPRADDRAAWL----ARIAAWRAEYLAAYAADDGPIKPQRVIAALREALPDDAIVVTDVGQHQMWA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 409 WSCWDARQ-GQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGG 486
Cdd:COG0028 394 ARYLRFRRpRRFLTSGGLGTMGYGLPAAIGAKL-----ARPDRpVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNNGG 468
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1718153936 487 YGILREYMVGAFGKAT-ATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:COG0028 469 LGMVRQWQELFYGGRYsGTDLPNPDFAKLAEAFGAKGERVEtPEELEAALEEALASDGPALIDVRV 534
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
18-549 |
7.25e-107 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 330.82 E-value: 7.25e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAMG--RGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK08266 6 GGEAIVAGLVAHGVDTVFGLPGAQLYWLFDALYkaGDRIRVIHTRHEQAAGYMAFGYARSTGRPGVCSVVPGPGVLNAGA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGaRRKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK08266 86 ALLTAYGCNSPVLCLTGQIPSALIG-KGRGHLHEMPDQLATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPRPVALE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLLdpiMVPPVEDALAEAADNPPRI--ELVREAVKWLEAARRPAIIAGGGTRRGKAEksLLSIAEKLRAPVICTPG 253
Cdd:PRK08266 165 MPWDVFG---QRAPVAAAPPLRPAPPPAPdpDAIAAAAALIAAAKNPMIFVGGGAAGAGEE--IRELAEMLQAPVVAFRS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 254 GNGAFPWNHELSLQ---AWiedrymtDVLEDADVLVVIGSSLgEVTSNYFTFEPRG-RIIQIDAEPRVLESNRPGLGIRA 329
Cdd:PRK08266 240 GRGIVSDRHPLGLNfaaAY-------ELWPQTDVVIGIGSRL-ELPTFRWPWRPDGlKVIRIDIDPTEMRRLKPDVAIVA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 330 DAGQALAALDEALQPGRAAAPDWHGATPEslvqeslAKVRARLESQDLGKELKFMADIREAVPADMQTFWDMTIAAYWGW 409
Cdd:PRK08266 312 DAKAGTAALLDALSKAGSKRPSRRAELRE-------LKAAARQRIQAVQPQASYLRAIREALPDDGIFVDELSQVGFASW 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 410 SCWDARQG-QFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGY 487
Cdd:PRK08266 385 FAFPVYAPrTFVTCGYQGTLGYGFPTALGAKV-----ANPDRpVVSITGDGGFMFGVQELATAVQHNIGVVTVVFNNNAY 459
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1718153936 488 GILREYMVGAF-GKATATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVVE 549
Cdd:PRK08266 460 GNVRRDQKRRFgGRVVASDLVNPDFVKLAESFGVAAFRVdSPEELRAALEAALAHGGPVLIEVP 523
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
19-549 |
2.87e-89 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 284.94 E-value: 2.87e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 19 GDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQ 98
Cdd:PRK07524 5 GEALVRLLEAYGVETVFGIPGVHTVELYRGLAGSGIRHVTPRHEQGAGFMADGYARVSGKPGVCFIITGPGMTNIATAMG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 99 EAYATGVPMVVVASQIPLEGLGARRkGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEIPQ 178
Cdd:PRK07524 85 QAYADSIPMLVISSVNRRASLGKGR-GKLHELPDQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEIPL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 179 NVLLDPIMVPPvEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRgkAEKSLLSIAEKLRAPVICTPGGNGAF 258
Cdd:PRK07524 164 DVLAAPADHLL-PAPPTRPARPGPAPAALAQAAERLAAARRPLILAGGGALA--AAAALRALAERLDAPVALTINAKGLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 259 PWNHELSL---QAWIEDRymtDVLEDADVLVVIGSSLGEVTSNYF---TFEPRGRIIQIDAEPRVLESN-RPGLGIRADA 331
Cdd:PRK07524 241 PAGHPLLLgasQSLPAVR---ALIAEADVVLAVGTELGETDYDVYfdgGFPLPGELIRIDIDPDQLARNyPPALALVGDA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 332 GQALAALDEALQPGrAAAPDWhGAtpeslvqESLAKVRARLESQDLGKEL---KFMADIREAVPaDMQTFWDMTIAAYWG 408
Cdd:PRK07524 318 RAALEALLARLPGQ-AAAADW-GA-------ARVAALRQALRAEWDPLTAaqvALLDTILAALP-DAIFVGDSTQPVYAG 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 409 WSCWDARQ--GQFHSAQGAGGLGFAFPGAIGAAVGleTQGRPgrVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGG 486
Cdd:PRK07524 388 NLYFDADAprRWFNASTGYGTLGYGLPAAIGAALG--APERP--VVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDG 463
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1718153936 487 YGILREYMVGAFGKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVE 549
Cdd:PRK07524 464 YGEIRRYMVARDIEPVGVDPYTPDFIALARAFGCAAERVAdLEQLQAALRAAFARPGPTLIEVD 527
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
17-551 |
3.08e-77 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 253.76 E-value: 3.08e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMG-RGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK07064 4 TVGELIAAFLEQCGVKTAFGVISIHNMPILDAIGrRGKIRFVPARGEAGAVNMADAHARVSGGLGVALTSTGTGAGNAAG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGARRkGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK07064 84 ALVEALTAGTPLLHITGQIETPYLDQDL-GYIHEAPDQLTMLRAVSKAAFRVRSAETALATIREAVRVALTAPTGPVSVE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLLDPImVPPVEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRR-GKAEKSLLsiaeKLRAPVICTPGG 254
Cdd:PRK07064 163 IPIDIQAAEI-ELPDDLAPVHVAVPEPDAAAVAELAERLAAARRPLLWLGGGARHaGAEVKRLV----DLGFGVVTSTQG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 255 NGAFPWNHELSLQAWIEDRYMTDVLEDADVLVVIGSSL-GEVTSNYFTFEPRgRIIQIDAEPRVLESNRPG-LGIRADAG 332
Cdd:PRK07064 238 RGVVPEDHPASLGAFNNSAAVEALYKTCDLLLVVGSRLrGNETLKYSLALPR-PLIRVDADAAADGRGYPNdLFVHGDAA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 333 QALAALDEALQPGRAAAPDWhgatpESLVQESLAKVRARLESQdLGKELKFMADIREAVPADMQTFWDMTIAAywgwSCW 412
Cdd:PRK07064 317 RVLARLADRLEGRLSVDPAF-----AADLRAAREAAVADLRKG-LGPYAKLVDALRAALPRDGNWVRDVTISN----STW 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 413 DARQGQFHSAQG-----AGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGG 486
Cdd:PRK07064 387 GNRLLPIFEPRAnvhalGGGIGQGLAMAIGAAL-----AGPGRkTVGLVGDGGLMLNLGELATAVQENANMVIVLMNDGG 461
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1718153936 487 YGILREYMVGAFGKATA-TELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVVETL 551
Cdd:PRK07064 462 YGVIRNIQDAQYGGRRYyVELHTPDFALLAASLGLPHWRVtSADDFEAVLREALAKEGPVLVEVDML 528
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
17-548 |
3.18e-72 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 240.50 E-value: 3.18e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLfLST-GPGALTSLA 95
Cdd:PRK08322 2 KAADLFVKCLENEGVEYIFGIPGEENLDLLEALRDSSIKLILTRHEQGAAFMAATYGRLTGKAGVC-LSTlGPGATNLVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEglgaRRKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK08322 81 GVAYAQLGGMPMVAITGQKPIK----RSKQGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNV-----LLDPIMVPPVEDALAEAAdnpprieLVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVIC 250
Cdd:PRK08322 157 LPEDIaaeetDGKPLPRSYSRRPYASPK-------AIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFT 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 251 TPGGNGAFPWNHELSL-QAWIEDR-YMTDVLEDADVLVVIGSSLGEvTSNYFTFEPRGR-IIQIDAEPRVLESNR-PGLG 326
Cdd:PRK08322 230 TQMGKGVIPETHPLSLgTAGLSQGdYVHCAIEHADLIINVGHDVIE-KPPFFMNPNGDKkVIHINFLPAEVDPVYfPQVE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 327 IRADAGQALAALDEALQPGRAAAPDWHGATPESLvqeslakvRARLE--SQDLG---KELKFMADIREAVPADmqtfwDM 401
Cdd:PRK08322 309 VVGDIANSLWQLKERLADQPHWDFPRFLKIREAI--------EAHLEegADDDRfpmKPQRIVADLRKVMPDD-----DI 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 402 TIA---AYwgwSCWDARqgQFHSAQ--------GAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELAT 469
Cdd:PRK08322 376 VILdngAY---KIWFAR--NYRAYEpntclldnALATMGAGLPSAIAAKL-----VHPDRkVLAVCGDGGFMMNSQELET 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 470 AKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVV 548
Cdd:PRK08322 446 AVRLGLPLVVLILNDNAYGMIRWKQENMGFEDFGLDFGNPDFVKYAESYGAKGYRVeSADDLLPTLEEALAQPGVHVIDC 525
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
17-546 |
3.10e-71 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 238.52 E-value: 3.10e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:PRK06048 9 TGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELYDSDLRHILVRHEQAAAHAADGYARATGKVGVCVATSGPGATNLVTG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEI 176
Cdd:PRK06048 89 IATAYMDSVPIVALTGQVPRSMIGNDA----FQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLIDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 177 PQNVLLDPIMVppvedalaeaaDNPPRIEL-------------VREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEK 243
Cdd:PRK06048 165 PKDVTTAEIDF-----------DYPDKVELrgykptykgnpqqIKRAAELIMKAERPIIYAGGGVISSNASEELVELAET 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 244 LRAPVICTPGGNGAFPWNHELSLQ--AWIEDRYMTDVLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLES 320
Cdd:PRK06048 234 IPAPVTTTLMGIGAIPTEHPLSLGmlGMHGTKYANYAIQESDLIIAVGARFDDrVTGKLASFAPNAKIIHIDIDPAEISK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 321 N-RPGLGIRADAGQALAALDEALQPGRAAapDWHGATPESLVQESLAKVrarlESQDLGKELKFMADIREAVPADMQTFW 399
Cdd:PRK06048 314 NvKVDVPIVGDAKQVLKSLIKYVQYCDRK--EWLDKINQWKKEYPLKYK----EREDVIKPQYVIEQIYELCPDAIIVTE 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 400 ----DMTIAAYWGWScwDARqgQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHN 474
Cdd:PRK06048 388 vgqhQMWAAQYFKYK--YPR--TFITSGGLGTMGYGFPAAIGAKV-----GKPDKtVIDIAGDGSFQMNSQELATAVQND 458
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1718153936 475 VPVTWLIVDDGGYGILREYMVGAFGKA-TATELA-RPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVV 546
Cdd:PRK06048 459 IPVIVAILNNGYLGMVRQWQELFYDKRySHTCIKgSVDFVKLAEAYGALGLRVEkPSEVRPAIEEAVASDRPVVI 533
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
17-557 |
4.25e-67 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 228.10 E-value: 4.25e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:PRK06276 2 KGAEAIIKALEAEGVKIIFGYPGGALLPFYDALYDSDLIHILTRHEQAAAHAADGYARASGKVGVCVATSGPGATNLVTG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGarrkgmlhqlDD--QKASAANV----TKSQRLIQHASGIPSAIQDAWTEAISSPQG 170
Cdd:PRK06276 82 IATAYADSSPVIALTGQVPTKLIG----------NDafQEIDALGIfmpiTKHNFQIKKPEEIPEIFRAAFEIAKTGRPG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 171 PVWLEIPQNVLLDPIMVP--PVEDALAEAADNPPRI---ELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLR 245
Cdd:PRK06276 152 PVHIDLPKDVQEGELDLEkyPIPAKIDLPGYKPTTFghpLQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 246 APVICTPGGNGAFPWNHELSL-QAWIEDRYMT-DVLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESN- 321
Cdd:PRK06276 232 IPVCTTLMGKGAFPEDHPLALgMVGMHGTKAAnYSVTESDVLIAIGCRFSDrTTGDISSFAPNAKIIHIDIDPAEIGKNv 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 322 RPGLGIRADAGQALAALDEALQPGRAAAPDWHGATPESLVQESLAKV---RARLESQDLGKELkfMADIREAVP-ADMQT 397
Cdd:PRK06276 312 RVDVPIVGDAKNVLRDLLAELMKKEIKNKSEWLERVKKLKKESIPRMdfdDKPIKPQRVIKEL--MEVLREIDPsKNTII 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 398 FWDMTIAAYWGWSCWDARQGQ-FHSAQGAGGLGFAFPGAIGAAVgletqGRPG-RVLAVSGDGSSMYSIAELATAKQHNV 475
Cdd:PRK06276 390 TTDVGQNQMWMAHFFKTSAPRsFISSGGLGTMGFGFPAAIGAKV-----AKPDaNVIAITGDGGFLMNSQELATIAEYDI 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 476 PVTWLIVDDGGYGILREYMVGAFGK-ATATELAR-PDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVV---- 548
Cdd:PRK06276 465 PVVICIFDNRTLGMVYQWQNLYYGKrQSEVHLGEtPDFVKLAESYGVKADRVeKPDEIKEALKEAIKSGEPYLLDIiidp 544
|
....*....
gi 1718153936 549 ETLLKMFGP 557
Cdd:PRK06276 545 AEALPMVPP 553
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
15-546 |
4.34e-62 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 213.97 E-value: 4.34e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAM-GRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK08199 7 ARTGGQILVDALRANGVERVFCVPGESYLAVLDALhDETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTRGPGATNA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGarRKGMlhQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVW 173
Cdd:PRK08199 87 SIGVHTAFQDSTPMILFVGQVARDFRE--REAF--QEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPGPVV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 174 LEIPQNVLLDPIMVPPVED-ALAEAADNPPRIELVREAvkwLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTP 252
Cdd:PRK08199 163 LALPEDVLSETAEVPDAPPyRRVAAAPGAADLARLAEL---LARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 253 GGNGAFPWNHelslqawieDRYMTDV-----------LEDADVLVVIGSSLGEVTSNYFTF----EPRGRIIQIDAEP-- 315
Cdd:PRK08199 240 RRQDLFDNRH---------PNYAGDLglginpalaarIREADLVLAVGTRLGEVTTQGYTLldipVPRQTLVHVHPDAee 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 316 --RVLesnRPGLGIRADAGQALAALDeALQPgrAAAPDWHGATpESLVQESLAKVRARLESQDLGKElKFMADIREAVPA 393
Cdd:PRK08199 311 lgRVY---RPDLAIVADPAAFAAALA-ALEP--PASPAWAEWT-AAAHADYLAWSAPLPGPGAVQLG-EVMAWLRERLPA 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 394 DmqtfwdmTI-----AAYWGWSCWDARQGQFHS--AQGAGGLGFAFPGAIGAAvgLETQGRPgrVLAVSGDGSSMYSIAE 466
Cdd:PRK08199 383 D-------AIitngaGNYATWLHRFFRFRRYRTqlAPTSGSMGYGLPAAIAAK--LLFPERT--VVAFAGDGCFLMNGQE 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 467 LATAKQHNVPVTWLIVDDGGYGILREYMVGAF-GKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPN 544
Cdd:PRK08199 452 LATAVQYGLPIIVIVVNNGMYGTIRMHQEREYpGRVSGTDLTNPDFAALARAYGGHGETVErTEDFAPAFERALASGKPA 531
|
..
gi 1718153936 545 VV 546
Cdd:PRK08199 532 LI 533
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
16-543 |
1.99e-60 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 209.35 E-value: 1.99e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 16 RNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK08978 1 MNGAQWVVHALRAQGVDTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGAAMAAIGYARATGKVGVCIATSGPGATNLIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGArrkGMLHQLDDQKASAAnVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK08978 81 GLADALLDSVPVVAITGQVSSPLIGT---DAFQEIDVLGLSLA-CTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLVD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLLDPIMVPPveDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTPGGN 255
Cdd:PRK08978 157 IPKDIQLAEGELEP--HLTTVENEPAFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 256 GAFPWNHELSL--------QAwiedryMTDVLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESNR-PGL 325
Cdd:PRK08978 235 GAVEADHPYYLgmlgmhgtKA------ANLAVQECDLLIAVGARFDDrVTGKLNTFAPHAKVIHLDIDPAEINKLRqAHV 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 326 GIRADAGQALAALDEALQPGraaapDWHgatpeSLVQESLAKVRARLESQ-DLGKELKFMADIREAVPADMQTFWD---- 400
Cdd:PRK08978 309 ALQGDLNALLPALQQPLNID-----AWR-----QHCAQLRAEHAWRYDHPgEAIYAPALLKQLSDRKPADTVVTTDvgqh 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 401 -MTIAAYwgwsCWDARQGQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVT 478
Cdd:PRK08978 379 qMWVAQH----MRFTRPENFITSSGLGTMGFGLPAAIGAQV-----ARPDDtVICVSGDGSFMMNVQELGTIKRKQLPVK 449
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1718153936 479 WLIVDDGGYGILREYMVGAF-GKATATELA-RPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGP 543
Cdd:PRK08978 450 IVLLDNQRLGMVRQWQQLFFdERYSETDLSdNPDFVMLASAFGIPGQTItRKDQVEAALDTLLNSEGP 517
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
16-548 |
4.25e-60 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 208.56 E-value: 4.25e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 16 RNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGAlTSLA 95
Cdd:PRK08617 5 KYGADLVVDSLINQGVKYVFGIPGAKIDRVFDALEDSGPELIVTRHEQNAAFMAAAIGRLTGKPGVVLVTSGPGV-SNLA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 -GLQEAYATGVPMVVVASQIPLeglgARRKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWL 174
Cdd:PRK08617 84 tGLVTATAEGDPVVAIGGQVKR----ADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 175 EIPQNVLLDPIMVPPVEdALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTPGG 254
Cdd:PRK08617 160 SLPQDVVDAPVTSKAIA-PLSKPKLGPASPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 255 NGAfpWNHELslqawiEDRYMTDV-----------LEDADVLVVIGSSLGEVTSNYFTFEPRGRIIQIDAEPRVLESN-R 322
Cdd:PRK08617 239 AGV--ISREL------EDHFFGRVglfrnqpgdelLKKADLVITIGYDPIEYEPRNWNSEGDATIIHIDVLPAEIDNYyQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 323 PGLGIRADAGQALAALDEALqPGRAAAPDwhgatpeslVQESLAKVRARLESQDLGKE---------LKFMADIREAVPA 393
Cdd:PRK08617 311 PERELIGDIAATLDLLAEKL-DGLSLSPQ---------SLEILEELRAQLEELAERPArleegavhpLRIIRALQDIVTD 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 394 DMQTFWDMT-----IAAYwgWSCWDARQGQFhsAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAEL 467
Cdd:PRK08617 381 DTTVTVDVGshyiwMARY--FRSYEPRHLLF--SNGMQTLGVALPWAIAAAL-----VRPGKkVVSVSGDGGFLFSAMEL 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 468 ATAKQHNVPVTWLIVDDGGYGilreyMVG-----AFGKATATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGD 541
Cdd:PRK08617 452 ETAVRLKLNIVHIIWNDGHYN-----MVEfqeemKYGRSSGVDFGPVDFVKYAESFGAKGLRVtSPDELEPVLREALATD 526
|
....*..
gi 1718153936 542 GPNVVVV 548
Cdd:PRK08617 527 GPVVIDI 533
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
17-543 |
3.97e-58 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 203.40 E-value: 3.97e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK08155 14 TGAELIVRLLERQGIRIVTGIPGGAILPLYDALSQsTQIRHILARHEQGAGFIAQGMARTTGKPAVCMACSGPGATNLVT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK08155 94 AIADARLDSIPLVCITGQVPASMIGTDA----FQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWID 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLLDPIMVPPVEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTPGGN 255
Cdd:PRK08155 170 IPKDVQTAVIELEALPAPAEKDAAPAFDEESIRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTLMAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 256 GAFPWNHELSL------QAwiedRYMTDVLEDADVLVVIGS-----SLGEVTSnyftFEPRGRIIQIDAEPRVLESNR-P 323
Cdd:PRK08155 250 GMLPKAHPLSLgmlgmhGA----RSTNYILQEADLLIVLGArfddrAIGKTEQ----FCPNAKIIHVDIDRAELGKIKqP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 324 GLGIRADAGQALAALDEALQPgrAAAPDWHgatpeSLVQEslAKVRARLESQDLGKELKFMADIReAVPADMQtfwDMTI 403
Cdd:PRK08155 322 HVAIQADVDDVLAQLLPLVEA--QPRAEWH-----QLVAD--LQREFPCPIPKADDPLSHYGLIN-AVAACVD---DNAI 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 404 AAYwgwscwDARQGQFHSAQ--------------GAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELA 468
Cdd:PRK08155 389 ITT------DVGQHQMWTAQayplnrprqwltsgGLGTMGFGLPAAIGAAL-----ANPERkVLCFSGDGSLMMNIQEMA 457
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1718153936 469 TAKQHNVPVTWLIVDDGGYGILREYMVGAFGKAT--ATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGP 543
Cdd:PRK08155 458 TAAENQLDVKIILMNNEALGLVHQQQSLFYGQRVfaATYPGKINFMQIAAGFGLETCDLnNEADPQAALQEAINRPGP 535
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
2-547 |
5.53e-57 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 201.43 E-value: 5.53e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 2 TELAAPAPAEGRGARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAM----GRGNLHFVSSRIENNSAFAADGYSRATG 77
Cdd:PRK07418 5 PPKIGDSTTVTPQRATGAYALMDSLKRHGVKHIFGYPGGAILPIYDELykaeAEGWLKHILVRHEQGAAHAADGYARATG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 78 EVGVLFLSTGPGALTSLAGLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAI 157
Cdd:PRK07418 85 KVGVCFGTSGPGATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDA----FQETDIFGITLPIVKHSYVVRDPSDMARIV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 158 QDAWTEAISSPQGPVWLEIPQNV---LLDPIMVPPVEDALA----EAADNPPRIElvrEAVKWLEAARRPAIIAGGGTRR 230
Cdd:PRK07418 161 AEAFHIASSGRPGPVLIDIPKDVgqeEFDYVPVEPGSVKPPgyrpTVKGNPRQIN---AALKLIEEAERPLLYVGGGAIS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 231 GKAEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSL-------QAwiedrYMTDVLEDADVLVVIGSSLGE-VTSNYFTF 302
Cdd:PRK07418 238 AGAHAELKELAERFQIPVTTTLMGKGAFDEHHPLSVgmlgmhgTA-----YANFAVTECDLLIAVGARFDDrVTGKLDEF 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 303 EPRGRIIQIDAEPRVLESNR-PGLGIRADAGQALAAL-DEALQPgraaapdwhgaTPESLVQESLAKVR----------- 369
Cdd:PRK07418 313 ASRAKVIHIDIDPAEVGKNRrPDVPIVGDVRKVLVKLlERSLEP-----------TTPPRTQAWLERINrwkqdyplvvp 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 370 ---ARLESQDLgkelkfMADIREAVPadmQTFWDMTIAAYWGWSCWDARQG--QFHSAQGAGGLGFAFPGAIGAAVGLET 444
Cdd:PRK07418 382 pyeGEIYPQEV------LLAVRDLAP---DAYYTTDVGQHQMWAAQFLRNGprRWISSAGLGTMGFGMPAAMGVKVALPD 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 445 QgrpgRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGK---ATATELARPDFVRLAESFGIP 521
Cdd:PRK07418 453 E----EVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQGMVRQWQESFYGErysASNMEPGMPDFVKLAEAFGVK 528
|
570 580 590
....*....|....*....|....*....|
gi 1718153936 522 ATRVA-PEDVGDALKAGFAGDGP---NVVV 547
Cdd:PRK07418 529 GMVISeRDQLKDAIAEALAHDGPvliDVHV 558
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
6-546 |
2.29e-54 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 193.26 E-value: 2.29e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 6 APAPAEGRGARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLS 85
Cdd:PRK06725 5 TTYEKLQCEEVTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYESGLKHILTRHEQAAIHAAEGYARASGKVGVVFAT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 86 TGPGALTSLAGLQEAYATGVPMVVVASQIPLEGLGarRKGMlhQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAI 165
Cdd:PRK06725 85 SGPGATNLVTGLADAYMDSIPLVVITGQVATPLIG--KDGF--QEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 166 SSPQGPVWLEIPQNVLLDPIMV--PPVEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEK 243
Cdd:PRK06725 161 SGRPGPVLIDIPKDVQNEKVTSfyNEVVEIPGYKPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFARE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 244 LRAPVICTPGGNGAFPWNHELSL-QAWIEDRYMTDV-LEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLES 320
Cdd:PRK06725 241 NRIPVVSTLMGLGAYPPGDPLFLgMLGMHGTYAANMaVTECDLLLALGVRFDDrVTGKLELFSPHSKKVHIDIDPSEFHK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 321 NRP-GLGIRADAGQALAALDEalQPGRAAAPDWhgatpeslvqesLAKVRARLESQDLGkelkFMADIREAVPAD-MQTF 398
Cdd:PRK06725 321 NVAvEYPVVGDVKKALHMLLH--MSIHTQTDEW------------LQKVKTWKEEYPLS----YKQKESELKPQHvINLV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 399 WDMT---------IAAYWGWSC--WDARQG-QFHSAQGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVSGDGSSMYSIAE 466
Cdd:PRK06725 383 SELTngeaivtteVGQHQMWAAhfYKAKNPrTFLTSGGLGTMGFGFPAAIGAQLAKEEE----LVICIAGDASFQMNIQE 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 467 LATAKQHNVPVTWLIVDDGGYGILREYMVGAF-GKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPN 544
Cdd:PRK06725 459 LQTIAENNIPVKVFIINNKFLGMVRQWQEMFYeNRLSESKIGSPDFVKVAEAYGVKGLRATnSTEAKQVMLEAFAHEGPV 538
|
..
gi 1718153936 545 VV 546
Cdd:PRK06725 539 VV 540
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
20-551 |
2.50e-54 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 192.48 E-value: 2.50e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 20 DLVVETLEALGAKTVFGIPGQHALGLFDAMgRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQE 99
Cdd:PRK07092 16 DATIDLLRRFGITTVFGNPGSTELPFLRDF-PDDFRYVLGLQEAVVVGMADGYAQATGNAAFVNLHSAAGVGNAMGNLFT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 100 AYATGVPMVVVASQ-----IPLEG-LGARRKGMLH----QLDDQKASAANVtksqrliqhasgiPSAIQDAWTEAISSPQ 169
Cdd:PRK07092 95 AFKNHTPLVITAGQqarsiLPFEPfLAAVQAAELPkpyvKWSIEPARAEDV-------------PAAIARAYHIAMQPPR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 170 GPVWLEIPQNVLLDPimVPPVEDALAEAADNPPRiELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVI 249
Cdd:PRK07092 162 GPVFVSIPYDDWDQP--AEPLPARTVSSAVRPDP-AALARLGDALDAARRPALVVGPAVDRAGAWDDAVRLAERHRAPVW 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 250 CTP-GGNGAFPWNHEL---SLQAWIEDryMTDVLEDADVLVVIGSSLgevtsnyFTFEPRG---------RIIQIDAEPr 316
Cdd:PRK07092 239 VAPmSGRCSFPEDHPLfagFLPASREK--ISALLDGHDLVLVIGAPV-------FTYHVEGpgphlpegaELVQLTDDP- 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 317 vLESNRPGLG--IRADAGQALAALDEALQPGRAAAPDWHgATPESLVQESLAKVRARLesqdlgkelkfMADIREAVPAD 394
Cdd:PRK07092 309 -GEAAWAPMGdaIVGDIRLALRDLLALLPPSARPAPPAR-PMPPPAPAPGEPLSVAFV-----------LQTLAALRPAD 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 395 -------------MQTFWDMTiaaywgwscwdaRQGQFHSAqGAGGLGFAFPGAIGAAVGletqgRPGR-VLAVSGDGSS 460
Cdd:PRK07092 376 aivveeapstrpaMQEHLPMR------------RQGSFYTM-ASGGLGYGLPAAVGVALA-----QPGRrVIGLIGDGSA 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 461 MYSIAELATAKQHNVPVTWLIVDDGGYGILREYM-VGAFGKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGF 538
Cdd:PRK07092 438 MYSIQALWSAAQLKLPVTFVILNNGRYGALRWFApVFGVRDVPGLDLPGLDFVALARGYGCEAVRVSdAAELADALARAL 517
|
570
....*....|...
gi 1718153936 539 AGDGPNVVVVETL 551
Cdd:PRK07092 518 AADGPVLVEVEVA 530
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
15-535 |
9.87e-53 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 188.88 E-value: 9.87e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK07282 9 PKSGSDLVLETLRDLGVDTIFGYPGGAVLPLYDAIYNfEGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTSGPGATNA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVW 173
Cdd:PRK07282 89 ITGIADAMSDSVPLLVFTGQVARAGIGKDA----FQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 174 LEIPQNV-------LLDPIMVPPVEDALAEAADnppriELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRA 246
Cdd:PRK07282 165 IDLPKDVsaletdfIYDPEVNLPSYQPTLEPND-----MQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 247 PVICTPGGNGAFPWNHELSL-QAWIEDRYMTDV-LEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEP----RVLE 319
Cdd:PRK07282 240 PVVTTLLGQGTIATSHPLFLgMGGMHGSYAANIaMTEADFMINIGSRFDDrLTGNPKTFAKNAKVAHIDIDPaeigKIIK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 320 SNRPGLGIRADAGQALAALDEAlqpgRAAAPDWhgatpESLVQESLAKVRARLESQDLGKELKFMADIREAVPADMQTFW 399
Cdd:PRK07282 320 TDIPVVGDAKKALQMLLAEPTV----HNNTEKW-----IEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVT 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 400 D-----MTIAAYWGWScwDARqgQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQH 473
Cdd:PRK07282 391 DvgqhqMWAAQYYPYQ--NER--QLVTSGGLGTMGFGIPAAIGAKI-----ANPDKeVILFVGDGGFQMTNQELAILNIY 461
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1718153936 474 NVPVTWLIVDDGGYGILREYMVGAFGKATATEL--ARPDFVRLAESFGIPATRVA-PEDVGDALK 535
Cdd:PRK07282 462 KVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVfdTLPDFQLMAQAYGIKHYKFDnPETLAQDLE 526
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
16-554 |
1.38e-51 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 186.10 E-value: 1.38e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 16 RNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGN-LHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSL 94
Cdd:PLN02470 13 RKGADILVEALEREGVDTVFAYPGGASMEIHQALTRSNcIRNVLCRHEQGEVFAAEGYAKASGKVGVCIATSGPGATNLV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 95 AGLQEAYATGVPMVVVASQIPleglgaRRkgMLHQLDDQKASAANVTKS----QRLIQHASGIPSAIQDAWTEAISSPQG 170
Cdd:PLN02470 93 TGLADALLDSVPLVAITGQVP------RR--MIGTDAFQETPIVEVTRSitkhNYLVMDVEDIPRVIREAFFLASSGRPG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 171 PVWLEIPQNV---LLDPIMVPPVE-DALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRrgKAEKSLLSIAEKLRA 246
Cdd:PLN02470 165 PVLVDIPKDIqqqLAVPNWNQPMKlPGYLSRLPKPPEKSQLEQIVRLISESKRPVVYVGGGCL--NSSEELREFVELTGI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 247 PVICTPGGNGAFPWNHELSLQ-----AWIEDRYMTDvleDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLES 320
Cdd:PLN02470 243 PVASTLMGLGAFPASDELSLQmlgmhGTVYANYAVD---SADLLLAFGVRFDDrVTGKLEAFASRASIVHIDIDPAEIGK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 321 NR-PGLGIRADAGQALAALDEALQPGRAAAPDwhgatpeslvqesLAKVRARLESQDLGKELKFmADIREAVPAD--MQT 397
Cdd:PLN02470 320 NKqPHVSVCADVKLALQGLNKLLEERKAKRPD-------------FSAWRAELDEQKEKFPLSY-PTFGDAIPPQyaIQV 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 398 FWDMT---------------IAAYWgwsCWDARQGQFHSAQGAGGLGFAFPGAIGAAVGletqgRPGR-VLAVSGDGSSM 461
Cdd:PLN02470 386 LDELTdgnaiistgvgqhqmWAAQW---YKYKEPRRWLTSGGLGAMGFGLPAAIGAAAA-----NPDAiVVDIDGDGSFI 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 462 YSIAELATAKQHNVPVTWLIVDDGGYGILREYMvGAFGKATA--TELAR--------PDFVRLAESFGIPATRVA-PEDV 530
Cdd:PLN02470 458 MNIQELATIHVENLPVKIMVLNNQHLGMVVQWE-DRFYKANRahTYLGDpdaeaeifPDFLKFAEGCKIPAARVTrKSDL 536
|
570 580
....*....|....*....|....*....
gi 1718153936 531 GDALKAGFAGDGP---NVVV--VETLLKM 554
Cdd:PLN02470 537 REAIQKMLDTPGPyllDVIVphQEHVLPM 565
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
18-539 |
1.60e-51 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 185.72 E-value: 1.60e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGN-LHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:PRK06466 6 GAEMLVRALRDEGVEYIYGYPGGAVLHIYDALFKQDkVEHILVRHEQAATHMADGYARATGKTGVVLVTSGPGATNAITG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEI 176
Cdd:PRK06466 86 IATAYMDSIPMVVLSGQVPSTLIGEDA----FQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVVDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 177 PQNvlldpiMVPPVEDAlaeAADNPPRIEL-------------VREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEK 243
Cdd:PRK06466 162 PKD------MTNPAEKF---EYEYPKKVKLrsyspavrghsgqIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 244 LRAPVICTPGGNGAFPWNHE-----LSLQAWIEDRyMTdvLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRV 317
Cdd:PRK06466 233 LNLPVTNTLMGLGGFPGTDRqflgmLGMHGTYEAN-MA--MHHADVILAVGARFDDrVTNGPAKFCPNAKIIHIDIDPAS 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 318 LESNrpglgIRAD---AGQALAALDEAL--------QPGRAAAPDW----------HGATPESLVQESLAKVRARLESqd 376
Cdd:PRK06466 310 ISKT-----IKADipiVGPVESVLTEMLailkeigeKPDKEALAAWwkqidewrgrHGLFPYDKGDGGIIKPQQVVET-- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 377 LGKELKFMADIREAVpADMQTFwdmtIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVSG 456
Cdd:PRK06466 383 LYEVTNGDAYVTSDV-GQHQMF----AAQYYKFN----KPNRWINSGGLGTMGFGLPAAMGVKLAFPDQ----DVACVTG 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 457 DGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREY--MVGAFGKATATELARPDFVRLAESFGIPATRVA-PEDVGDA 533
Cdd:PRK06466 450 EGSIQMNIQELSTCLQYGLPVKIINLNNGALGMVRQWqdMQYEGRHSHSYMESLPDFVKLAEAYGHVGIRITdLKDLKPK 529
|
....*.
gi 1718153936 534 LKAGFA 539
Cdd:PRK06466 530 LEEAFA 535
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
5-547 |
9.11e-51 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 184.03 E-value: 9.11e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 5 AAPAPAEGRGAR------NGGDLVVETLEALGAKTVFGIPGQHALGLFDA-MGRGNLHFVSSRIENNSAFAADGYSRATG 77
Cdd:PRK07789 14 PPPAAPAARPRIvapermTGAQAVVRSLEELGVDVVFGIPGGAILPVYDPlFDSTKVRHVLVRHEQGAGHAAEGYAQATG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 78 EVGVLFLSTGPGALTSLAGLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAI 157
Cdd:PRK07789 94 RVGVCMATSGPGATNLVTPIADANMDSVPVVAITGQVGRGLIGTDA----FQEADIVGITMPITKHNFLVTDADDIPRVI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 158 QDAWTEAISSPQGPVWLEIPQnvlldpimvppveDALAEAADN--PPRIEL-------------VREAVKWLEAARRPAI 222
Cdd:PRK07789 170 AEAFHIASTGRPGPVLVDIPK-------------DALQAQTTFswPPRMDLpgyrpvtkphgkqIREAAKLIAAARRPVL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 223 IAGGGTRRGKAEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSLQawiedryM---------TDVLEDADVLVVIGSSLG 293
Cdd:PRK07789 237 YVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLG-------MpgmhgtvaaVAALQRSDLLIALGARFD 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 294 E-VTSNYFTFEPRGRIIQIDAEPRVLESNR-PGLGIRADAGQALAALDEALQPGRAAAPdwhgatpeslvqeslakvrar 371
Cdd:PRK07789 310 DrVTGKLDSFAPDAKVIHADIDPAEIGKNRhADVPIVGDVKEVIAELIAALRAEHAAGG--------------------- 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 372 leSQDLGKELKFMADIREAVPADMQTFWDMTIAAYW------------GWSCWDARQGQFHSAQ--------------GA 425
Cdd:PRK07789 369 --KPDLTAWWAYLDGWRETYPLGYDEPSDGSLAPQYvierlgeiagpdAIYVAGVGQHQMWAAQfidyekprtwlnsgGL 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 426 GGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMvGAF--GKAT 502
Cdd:PRK07789 447 GTMGYAVPAAMGAKV-----GRPDKeVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGMVRQWQ-TLFyeERYS 520
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1718153936 503 ATELAR-----PDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVV 547
Cdd:PRK07789 521 NTDLHThshriPDFVKLAEAYGCVGLRCeREEDVDAVIEKARAINDRPVVI 571
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
18-548 |
1.08e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 183.12 E-value: 1.08e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDA----MGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK06456 4 GARILVDSLKREGVKVIFGIPGLSNMQIYDAfvedLANGELRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGTTNL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGArrkgMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVW 173
Cdd:PRK06456 84 VTGLITAYWDSSPVIAITGQVPRSVMGK----MAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 174 LEIPQNVLLDPI--MVPPVEDALAEAADNPPRI--ELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVI 249
Cdd:PRK06456 160 IDIPRDIFYEKMeeIKWPEKPLVKGYRDFPTRIdrLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 250 CTPGGNGAFPWNHELSLQA---WIEDRYMTDVLEdADVLVVIGSSLGE--VTSNYFTFEPRGRIIQIDAEPRVLESN-RP 323
Cdd:PRK06456 240 STFPGKTAIPHDHPLYFGPmgyYGRAEASMAALE-SDAMLVVGARFSDrtFTSYDEMVETRKKFIMVNIDPTDGEKAiKV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 324 GLGIRADAGQAL-----AALDEALQPGRAAapdWHGATPEslVQESLAKVRARLESQDLgKELKFMADIREAVPADMQTF 398
Cdd:PRK06456 319 DVGIYGNAKIILrelikAITELGQKRDRSA---WLKRVKE--YKEYYSQFYYTEENGKL-KPWKIMKTIRQALPRDAIVT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 399 WDMTIAAYWGWSCWDARQGQ-FHSAQGAGGLGFAFPGAIGAAVgletqGRPGRVLA-VSGDGSSMYSIAELATAKQHNVP 476
Cdd:PRK06456 393 TGVGQHQMWAEVFWEVLEPRtFLTSSGMGTMGFGLPAAMGAKL-----ARPDKVVVdLDGDGSFLMTGTNLATAVDEHIP 467
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1718153936 477 VTWLIVDDGGYGILREYMVGAFGK--ATATELARPDFVRLAESFGIPATRVAP-EDVGDALKAGFAGDGPNVVVV 548
Cdd:PRK06456 468 VISVIFDNRTLGLVRQVQDLFFGKriVGVDYGPSPDFVKLAEAFGALGFNVTTyEDIEKSLKSAIKEDIPAVIRV 542
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
18-188 |
1.83e-50 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 171.26 E-value: 1.83e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAM-GRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDALaKSPGIRYVLTRHEQGAAFAADGYARATGKPGVVLVTSGPGATNALTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGarrKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEI 176
Cdd:pfam02776 81 LANAYVDSVPLLVISGQRPRSLVG---RGALQQELDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEI 157
|
170
....*....|..
gi 1718153936 177 PQNVLLDPIMVP 188
Cdd:pfam02776 158 PLDVLLEEVDED 169
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
17-519 |
3.76e-50 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 181.97 E-value: 3.76e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK07979 5 SGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTvGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK07979 85 GIATAYMDSIPLVVLSGQVATSLIGYDA----FQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLLDPIMVPPV-EDALAEAADNPP---RIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICT 251
Cdd:PRK07979 161 LPKDILNPANKLPYVwPESVSMRSYNPTtqgHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVVSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 252 PGGNGAFPWNHELSLQAW-IEDRYMTDV-LEDADVLVVIGSSLGEVTSNYFT-FEPRGRIIQIDAEPRVLESNRPG-LGI 327
Cdd:PRK07979 241 LMGLGAFPATHRQSLGMLgMHGTYEANMtMHNADVIFAVGVRFDDRTTNNLAkYCPNATVLHIDIDPTSISKTVTAdIPI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 328 RADAGQALAALDEALQPGRAAAP-----DWhgatpeslvQESLAKVRARlesqdlgKELKFMADIREAVP-ADMQTFWDM 401
Cdd:PRK07979 321 VGDARQVLEQMLELLSQESAHQPldeirDW---------WQQIEQWRAR-------QCLKYDTHSEKIKPqAVIETLWRL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 402 TIAAYWGWScwDARQGQFHSA--------------QGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVSGDGSSMYSIAEL 467
Cdd:PRK07979 385 TKGDAYVTS--DVGQHQMFAAlyypfdkprrwinsGGLGTMGFGLPAALGVKMALPEE----TVVCVTGDGSIQMNIQEL 458
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 1718153936 468 ATAKQHNVPVTWLIVDDGGYGILREY--MVGAFGKATATELARPDFVRLAESFG 519
Cdd:PRK07979 459 STALQYELPVLVLNLNNRYLGMVKQWqdMIYSGRHSQSYMQSLPDFVRLAEAYG 512
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
17-539 |
8.53e-50 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 180.88 E-value: 8.53e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK06882 5 SGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTlGGIEHVLVRHEQAAVHMADGYARSTGKVGCVLVTSGPGATNAIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK06882 85 GIATAYTDSVPLVILSGQVPSNLIGTDA----FQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVID 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVlldpimvppVEDALAEAADNPPRIEL-------------VREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAE 242
Cdd:PRK06882 161 IPKDM---------VNPANKFTYEYPEEVSLrsynptvqghkgqIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQ 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 243 KLRAPVICTPGGNGAFP-----WNHELSLQAWIEdryMTDVLEDADVLVVIGSSLGEVTSNYFT-FEPRGRIIQIDAEPR 316
Cdd:PRK06882 232 KLNLPVTSSLMGLGAYPstdkqFLGMLGMHGTYE---ANNAMHESDLILGIGVRFDDRTTNNLAkYCPNAKVIHIDIDPT 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 317 VLESNRPG-LGIRADAGQALAAL-----DEALQPGRAAAPDWHGATPESLVQESLAKVRarleSQDLGKELKFMADIREA 390
Cdd:PRK06882 309 SISKNVPAyIPIVGSAKNVLEEFlslleEENLAKSQTDLTAWWQQINEWKAKKCLEFDR----TSDVIKPQQVVEAIYRL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 391 VPADMQTFWD-----MTIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPgaigAAVGLETQGRPGRVLAVSGDGSSMYSIA 465
Cdd:PRK06882 385 TNGDAYVASDvgqhqMFAALHYPFD----KPRRWINSGGAGTMGFGLP----AAIGVKFAHPEATVVCVTGDGSIQMNIQ 456
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1718153936 466 ELATAKQHNVPVTWLIVDDGGYGILREYMVGAF-GKATATEL-ARPDFVRLAESFGIPATRVA-PEDVGDALKAGFA 539
Cdd:PRK06882 457 ELSTAKQYDIPVVIVSLNNRFLGMVKQWQDLIYsGRHSQVYMnSLPDFAKLAEAYGHVGIQIDtPDELEEKLTQAFS 533
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
17-539 |
1.17e-49 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 180.40 E-value: 1.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAM-GRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK08979 5 SGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALhEKSGIEHILVRHEQAAVHMADGYARATGKVGVVLVTSGPGATNTIT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLE 175
Cdd:PRK08979 85 GIATAYMDSIPMVVLSGQVPSNLIGNDA----FQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVID 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 176 IPQNVLlDPIMVPPVE--DALAEAADNPPRIE---LVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVIC 250
Cdd:PRK08979 161 LPKDCL-NPAILHPYEypESIKMRSYNPTTSGhkgQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVVS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 251 TPGGNGAFPWNHELSLQAW-IEDRYMTDV-LEDADVLVVIGSSLGEVTSNYF-TFEPRGRIIQIDAEPRVLESNrpglgI 327
Cdd:PRK08979 240 TLMGLGAFPGTHKNSLGMLgMHGRYEANMaMHNADLIFGIGVRFDDRTTNNLeKYCPNATILHIDIDPSSISKT-----V 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 328 RAD---AGQALAALDEAL-----QPGR---AAAPDWHGATPESLVQESLA--KVRARLESQDLGKELKFMADIREAVPAD 394
Cdd:PRK08979 315 RVDipiVGSADKVLDSMLalldeSGETndeAAIASWWNEIEVWRSRNCLAydKSSERIKPQQVIETLYKLTNGDAYVASD 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 395 MQTFwDMTIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVSGDGSSMYSIAELATAKQHN 474
Cdd:PRK08979 395 VGQH-QMFAALYYPFD----KPRRWINSGGLGTMGFGLPAAMGVKFAMPDE----TVVCVTGDGSIQMNIQELSTALQYD 465
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1718153936 475 VPVTWLIVDDGGYGILREY--MVGAFGKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFA 539
Cdd:PRK08979 466 IPVKIINLNNRFLGMVKQWqdMIYQGRHSHSYMDSVPDFAKIAEAYGHVGIRISdPDELESGLEKALA 533
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
17-554 |
5.48e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 178.37 E-value: 5.48e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNlHF--VSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSL 94
Cdd:PRK08527 4 SGSQMVCEALKEEGVKVVFGYPGGAILNIYDEIYKQN-YFkhILTRHEQAAVHAADGYARASGKVGVAIVTSGPGFTNAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 95 AGLQEAYATGVPMVVVASQIPLEGLGArrkgmlhqldD--QKASAANV----TKSQRLIQHASGIPSAIQDAWTEAISSP 168
Cdd:PRK08527 83 TGLATAYMDSIPLVLISGQVPNSLIGT----------DafQEIDAVGIsrpcVKHNYLVKSIEELPRILKEAFYIARSGR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 169 QGPVWLEIPQNVlldpimvppvEDALAEAaDNPPRIEL-------------VREAVKWLEAARRPAIIAGGGTRRGKAEK 235
Cdd:PRK08527 153 PGPVHIDIPKDV----------TATLGEF-EYPKEISLktykptykgnsrqIKKAAEAIKEAKKPLFYLGGGAILSNASE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 236 SLLSIAEKLRAPVICTPGGNGAFPWNHELSL-QAWIEDRYMTDV-LEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQID 312
Cdd:PRK08527 222 EIRELVKKTGIPAVETLMARGVLRSDDPLLLgMLGMHGSYAANMaMSECDLLISLGARFDDrVTGKLSEFAKHAKIIHVD 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 313 AEP----RVLESNRPglgIRADAGQALAALDEALQ---PGRAAApdWHgatpeslvqESLAKVRAR--LESQDLGKELK- 382
Cdd:PRK08527 302 IDPssisKIVNADYP---IVGDLKNVLKEMLEELKeenPTTYKE--WR---------EILKRYNELhpLSYEDSDEVLKp 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 383 --FMADIREAVPADMQTFWD-----MTIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVS 455
Cdd:PRK08527 368 qwVIERVGELLGDDAIISTDvgqhqMWVAQFYPFN----YPRQLATSGGLGTMGYGLPAALGAKLAVPDK----VVINFT 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 456 GDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKA-TATEL-ARPDFVRLAESFGIPATRVAPEDVGD- 532
Cdd:PRK08527 440 GDGSILMNIQELMTAVEYKIPVINIILNNNFLGMVRQWQTFFYEERySETDLsTQPDFVKLAESFGGIGFRVTTKEEFDk 519
|
570 580
....*....|....*....|....*..
gi 1718153936 533 ALKAGFAGDGPNVVVV-----ETLLKM 554
Cdd:PRK08527 520 ALKEALESDKVALIDVkidrfENVLPM 546
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
17-557 |
6.60e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 178.42 E-value: 6.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:PRK07710 17 TGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALYDCGIPHILTRHEQGAIHAAEGYARISGKPGVVIATSGPGATNVVTG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEI 176
Cdd:PRK07710 97 LADAMIDSLPLVVFTGQVATSVIGSDA----FQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLIDI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 177 PQNVLLD------------PIMVPPVEdalaeaadnpPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKL 244
Cdd:PRK07710 173 PKDMVVEegefcydvqmdlPGYQPNYE----------PNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQ 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 245 RAPVICTPGGNGAFPWNHELSL-QAWIEDRYMTDV-LEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESN 321
Cdd:PRK07710 243 EIPVVHTLLGLGGFPADHPLFLgMAGMHGTYTANMaLYECDLLINIGARFDDrVTGNLAYFAKEATVAHIDIDPAEIGKN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 322 RP-GLGIRADAGQALAALDEalQPGRaaapdwHGATPESLVQESLAKVRARLESQDLGKELKFMADIR--------EAVP 392
Cdd:PRK07710 323 VPtEIPIVADAKQALQVLLQ--QEGK------KENHHEWLSLLKNWKEKYPLSYKRNSESIKPQKAIEmlyeitkgEAIV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 393 ADMQTFWDMTIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPGAIGAAVGletqGRPGRVLAVSGDGSSMYSIAELATAKQ 472
Cdd:PRK07710 395 TTDVGQHQMWAAQYYPFK----TPDKWVTSGGLGTMGFGLPAAIGAQLA----KPDETVVAIVGDGGFQMTLQELSVIKE 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 473 HNVPVTWLIVDDGGYGILREYMVGAFGKATATEL--ARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGP-----N 544
Cdd:PRK07710 467 LSLPVKVVILNNEALGMVRQWQEEFYNQRYSHSLlsCQPDFVKLAEAYGIKGVRIdDELEAKEQLQHAIELQEPvvidcR 546
|
570
....*....|...
gi 1718153936 545 VVVVETLLKMFGP 557
Cdd:PRK07710 547 VLQSEKVMPMVAP 559
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
4-557 |
1.04e-48 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 178.03 E-value: 1.04e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 4 LAAPAPAEG-RGARNGGDLVVETLEALGAKTVFG--IPGqhalGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVG 80
Cdd:PRK06112 1 LSKPLSAPGfTLNGTVAHAIARALKRHGVEQIFGqsLPS----ALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 81 VLFLSTGPGALTSLAGLQEAYATGVPMVVVASQIPLeglgarrkgmlHQLD-------DQKASAANVTKSQRLIQHASGI 153
Cdd:PRK06112 77 VVTAQNGPAATLLVAPLAEALKASVPIVALVQDVNR-----------DQTDrnafqelDHIALFQSCTKWVRRVTVAERI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 154 PSAIQDAWTEAISSPQGPVWLEIPQNVLLDPIMVPPVEDA-------LAEAADNPPRIElvrEAVKWLEAARRPAIIAGG 226
Cdd:PRK06112 146 DDYVDQAFTAATSGRPGPVVLLLPADLLTAAAAAPAAPRSnslghfpLDRTVPAPQRLA---EAASLLAQAQRPVVVAGG 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 227 GTRRGKAEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSLQAWIE-------DRYMTDVLEDADVLVVIGSSLGEV-TSN 298
Cdd:PRK06112 223 GVHISGASAALAALQSLAGLPVATTNMGKGAVDETHPLSLGVVGSlmgprspGRHLRDLVREADVVLLVGTRTNQNgTDS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 299 YFTFEPRGRIIQIDAEPRVLESNRPGLGIRADAGQALAALDEALQP-GRAAAPDWHGATPESLVQ--ESLAKVRARLESQ 375
Cdd:PRK06112 303 WSLYPEQAQYIHIDVDGEEVGRNYEALRLVGDARLTLAALTDALRGrDLAARAGRRAALEPAIAAgrEAHREDSAPVALS 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 376 DLG--KELKFMADIREAVPADMQTFWDMTIAAYWGWSCWDARQ-GQ-FHSAQGAGGLGFAFPGAIGAAVgletqGRPG-R 450
Cdd:PRK06112 383 DASpiRPERIMAELQAVLTGDTIVVADASYSSIWVANFLTARRaGMrFLTPRGLAGLGWGVPMAIGAKV-----ARPGaP 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 451 VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKAT-ATELARPDFVRLAESFGIPATRVA-PE 528
Cdd:PRK06112 458 VICLVGDGGFAHVWAELETARRMGVPVTIVVLNNGILGFQKHAETVKFGTHTdACHFAAVDHAAIARACGCDGVRVEdPA 537
|
570 580
....*....|....*....|....*....
gi 1718153936 529 DVGDALKAGFAGDGPNVVVVETLLKMFGP 557
Cdd:PRK06112 538 ELAQALAAAMAAPGPTLIEVITDPSAFPP 566
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
9-537 |
8.94e-47 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 172.30 E-value: 8.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 9 PAEGRgARNGGDLVVETLEALGAKTVFGIPGQHalgLFDAMGRGNLHFVSSRIENNSAFAADGYSRATG--EVGVLFLST 86
Cdd:PRK06154 14 PAEAK-TMKVAEAVAEILKEEGVELLFGFPVNE---LFDAAAAAGIRPVIARTERVAVHMADGYARATSgeRVGVFAVQY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 87 GPGALTSLAGLQEAYATGVPMVVVASQIPleglgaRRKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAIS 166
Cdd:PRK06154 90 GPGAENAFGGVAQAYGDSVPVLFLPTGYP------RGSTDVAPNFESLRNYRHITKWCEQVTLPDEVPELMRRAFTRLRN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 167 SPQGPVWLEIPQNVLLDPIMVPPVEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRA 246
Cdd:PRK06154 164 GRPGPVVLELPVDVLAEELDELPLDHRPSRRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELKELAELLEI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 247 PVICTPGGNGAFPWNHELSLQA--WIEDRYMTDVLEDADVLVVIGSSLGEvtSNYFTFEPRGR-IIQIDAEPRVLESNRP 323
Cdd:PRK06154 244 PVMTTLNGKSAFPEDHPLALGSggRARPATVAHFLREADVLFGIGCSLTR--SYYGLPMPEGKtIIHSTLDDADLNKDYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 324 -GLGIRADAGQALAALDEAL------QPGRAAAPdwhGATPESLVQESLAKVRARLESQD-------LGKELKFMADIRE 389
Cdd:PRK06154 322 iDHGLVGDAALVLKQMIEELrrrvgpDRGRAQQV---AAEIEAVRAAWLAKWMPKLTSDStpinpyrVVWELQHAVDIKT 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 390 AV-------PAD-MQTFWDMTI-AAYWGWScwdarqgqfHSAQGAGGLGFafpgAIGAAVgletqGRPGR-VLAVSGDGS 459
Cdd:PRK06154 399 VIithdagsPRDqLSPFYVASRpGSYLGWG---------KTTQLGYGLGL----AMGAKL-----ARPDAlVINLWGDAA 460
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 460 SMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATELArPDFVRLAESFGIPATRVA-PEDVGDALKAG 537
Cdd:PRK06154 461 FGMTGMDFETAVRERIPILTILLNNFSMGGYDKVMPVSTTKYRATDIS-GDYAAIARALGGYGERVEdPEMLVPALLRA 538
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
19-519 |
4.62e-46 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 169.95 E-value: 4.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 19 GDLVVETLEALGAKTVFGIPGQHALGLFDAM-GRGNLHFVSSRIENNSAFAADGYSRATGeVGVLFLSTGPGALTSLAGL 97
Cdd:COG3961 8 GDYLLDRLAELGIRHIFGVPGDYNLPFLDAIeAHPGIRWVGCCNELNAGYAADGYARVNG-LGALVTTYGVGELSAINGI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 98 QEAYATGVPmVVVASQIPleGLGARRKGML--HQL-----DDQKASAANVTKSQRLI--QHA-SGIPSAIQDAWTEaiss 167
Cdd:COG3961 87 AGAYAERVP-VVHIVGAP--GTRAQRRGPLlhHTLgdgdfDHFLRMFEEVTVAQAVLtpENAaAEIDRVLAAALRE---- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 168 pQGPVWLEIPQNVLLDPIMVPPVEDALAEAADNPPRI-ELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRA 246
Cdd:COG3961 160 -KRPVYIELPRDVADAPIEPPEAPLPLPPPASDPAALaAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKTGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 247 PVICTPGGNGAFPWNH---------ELSlqawieDRYMTDVLEDADVLVVIGSSLGEVTSNYFTFE-PRGRIIQIDAEP- 315
Cdd:COG3961 239 PVATTLLGKSVLDESHpqfigtyagAAS------SPEVREYVENADCVLCLGVVFTDTNTGGFTAQlDPERTIDIQPDSv 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 316 RVLESNRPGLGIrADAGQALAALDEALQPGRAA----APDWHGATPESLVQESL-AKVRARLESQDL-----GKELKFMA 385
Cdd:COG3961 313 RVGGHIYPGVSL-ADFLEALAELLKKRSAPLPApappPPPPPAAPDAPLTQDRLwQRLQAFLDPGDIvvadtGTSLFGAA 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 386 DIReaVPADM----QTFWdmtiaaywgwscwdarqgqfhsaqgaGGLGFAFPGAIGAAVgletqGRPG-RVLAVSGDGSS 460
Cdd:COG3961 392 DLR--LPEGAtfiaQPLW--------------------------GSIGYTLPAALGAAL-----AAPDrRVILLVGDGAF 438
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 461 MYSIAELATAKQHNVPVTWLIVDDGGYGILReYMVGAfgKATATELARPDFVRLAESFG 519
Cdd:COG3961 439 QLTAQELSTMLRYGLKPIIFVLNNDGYTIER-AIHGP--DGPYNDIANWDYAKLPEAFG 494
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
2-538 |
4.69e-45 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 168.06 E-value: 4.69e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 2 TELAAPAPAEGRGAR-NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGN-LHFVSSRIENNSAFAADGYSRATGEV 79
Cdd:PRK06965 6 AEFSTAESLSPPAADsIGAEILMKALAAEGVEFIWGYPGGAVLYIYDELYKQDkIQHVLVRHEQAAVHAADGYARATGKV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 80 GVLFLSTGPGALTSLAGLQEAYATGVPMVVVASQIPLEGLGarrkgmlhqLDD-QKASAANVT----KSQRLIQHASGIP 154
Cdd:PRK06965 86 GVALVTSGPGVTNAVTGIATAYMDSIPMVVISGQVPTAAIG---------QDAfQECDTVGITrpivKHNFLVKDVRDLA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 155 SAIQDAWTEAISSPQGPVWLEIPQNVLLDPIMVPPVEdALAEAADNPPR---IELVREAVKWLEAARRPAIIAGGGTRRG 231
Cdd:PRK06965 157 ETVKKAFYIARTGRPGPVVVDIPKDVSKTPCEYEYPK-SVEMRSYNPVTkghSGQIRKAVSLLLSAKRPYIYTGGGVILA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 232 KAEKSLLSIAEKLRAPVICTPGGNGAFPWNHE-----LSLQAWIEdryMTDVLEDADVLVVIGSSLGE-VTSN--YFTFE 303
Cdd:PRK06965 236 NASRELRQLADLLGYPVTNTLMGLGAYPASDKkflgmLGMHGTYE---ANMAMQHCDVLIAIGARFDDrVIGNpaHFASR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 304 PRgRIIQIDAEPRVLeSNR-----PGLGIRADAGQALAAL--DEALQPGRAAAPDWHGATPESLVQESLAKVRarleSQD 376
Cdd:PRK06965 313 PR-KIIHIDIDPSSI-SKRvkvdiPIVGDVKEVLKELIEQlqTAEHGPDADALAQWWKQIEGWRSRDCLKYDR----ESE 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 377 LGKElKFMadireavpadMQTFWDMTIA-AYwgwSCWDARQGQFHSAQ-----------GAGGLGFAFPGaIGAAVGLET 444
Cdd:PRK06965 387 IIKP-QYV----------VEKLWELTDGdAF---VCSDVGQHQMWAAQfyrfneprrwiNSGGLGTMGVG-LPYAMGIKM 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 445 QGRPGRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATEL--ARPDFVRLAESFGIPA 522
Cdd:PRK06965 452 AHPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNRYLGMVRQWQEIEYSKRYSHSYmdALPDFVKLAEAYGHVG 531
|
570
....*....|....*..
gi 1718153936 523 TRVA-PEDVGDALKAGF 538
Cdd:PRK06965 532 MRIEkTSDVEPALREAL 548
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
18-543 |
1.49e-44 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 166.42 E-value: 1.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGN-LHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAG 96
Cdd:PRK09107 13 GAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIFQQDdIQHILVRHEQGAGHAAEGYARSTGKPGVVLVTSGPGATNAVTP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 97 LQEAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEI 176
Cdd:PRK09107 93 LQDALMDSIPLVCITGQVPTHLIGSDA----FQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVVVDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 177 PQNV-LLDPIMVPPVEDALAEAADNPPR--IELVREAVKWLEAARRPAIIAGGG--TRRGKAEKSLLSIAEKLRAPVICT 251
Cdd:PRK09107 169 PKDVqFATGTYTPPQKAPVHVSYQPKVKgdAEAITEAVELLANAKRPVIYSGGGviNSGPEASRLLRELVELTGFPITST 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 252 PGGNGAFPwnheLSLQAWIEDRYMTDVLE------DADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESN-RP 323
Cdd:PRK09107 249 LMGLGAYP----ASGKNWLGMLGMHGTYEanmamhDCDVMLCVGARFDDrITGRLDAFSPNSKKIHIDIDPSSINKNvRV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 324 GLGIRADAGQALAAL-----DEALQPGRAAAPDWHGATPESLVQESLAKVRA-----------RLESQDLGKELKFMADI 387
Cdd:PRK09107 325 DVPIIGDVGHVLEDMlrlwkARGKKPDKEALADWWGQIARWRARNSLAYTPSddvimpqyaiqRLYELTKGRDTYITTEV 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 388 REAvpadmqtfwDMTIAAYWGWScwdaRQGQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAE 466
Cdd:PRK09107 405 GQH---------QMWAAQFFGFE----EPNRWMTSGGLGTMGYGLPAALGVQI-----AHPDAlVIDIAGDASIQMCIQE 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 467 LATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATA---TElARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDG 542
Cdd:PRK09107 467 MSTAVQYNLPVKIFILNNQYMGMVRQWQQLLHGNRLShsyTE-AMPDFVKLAEAYGAVGIRCEkPGDLDDAIQEMIDVDK 545
|
.
gi 1718153936 543 P 543
Cdd:PRK09107 546 P 546
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
18-550 |
4.16e-44 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 164.51 E-value: 4.16e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGL 97
Cdd:PRK05858 7 AGRLAARRLKAHGVDTMFTLSGGHLFPLYDGAREEGIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTAGPGVTNGMSAM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 98 QEAYATGVPMVVVASQIPLEGLGArrkGMLHQLdDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEIP 177
Cdd:PRK05858 87 AAAQFNQSPLVVLGGRAPALRWGM---GSLQEI-DHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVDFP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 178 QNVLLDPIMVPPVEDALAEA-ADNPPRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTPGGNG 256
Cdd:PRK05858 163 MDHAFSMADDDGRPGALTELpAGPTPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 257 AFPWNHELSLQawiedRYMTDVLEDADVLVVIGSSLgEVTSNYFTFEPRGRIIQIDAEPRVLESNR-PGLGIRADAGQAL 335
Cdd:PRK05858 243 VVPADHPLAFS-----RARGKALGEADVVLVVGVPM-DFRLGFGVFGGTAQLVHVDDAPPQRAHHRpVAAGLYGDLSAIL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 336 AALDEALQPGRAAApDWHGATPESlvqESLAKVRARLESQDLGKELKFM---ADIREAVPADMQTFWDM-TIAAYWGWSC 411
Cdd:PRK05858 317 SALAGAGGDRTDHQ-GWIEELRTA---ETAARARDAAELADDRDPIHPMrvyGELAPLLDRDAIVIGDGgDFVSYAGRYI 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 412 WDARQGQFHSAQGAGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGIL 490
Cdd:PRK05858 393 DPYRPGCWLDPGPFGCLGTGPGYALAARL-----ARPSRqVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVIGNNGIWGLE 467
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1718153936 491 REYMVGAFGKATATELA---RPDFVRLAESfGIPATRVAPEDVGDALKAGFAGDGPNVVVVET 550
Cdd:PRK05858 468 KHPMEALYGYDVAADLRpgtRYDEVVRALG-GHGELVTVPAELGPALERAFASGVPYLVNVLT 529
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
383-550 |
8.24e-44 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 153.18 E-value: 8.24e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 383 FMADIREAVPADMQTFWDMTIAAYWGWSCWDARQGQ-FHSAQGAGGLGFAFPGAIGAAVGletqgRPGR-VLAVSGDGSS 460
Cdd:cd00568 2 VLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRrFLTSTGFGAMGYGLPAAIGAALA-----APDRpVVCIAGDGGF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 461 MYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAF-GKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGF 538
Cdd:cd00568 77 MMTGQELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFYgGRVSGTDLSNPDFAALAEAYGAKGVRVEdPEDLEAALAEAL 156
|
170
....*....|..
gi 1718153936 539 AGDGPNVVVVET 550
Cdd:cd00568 157 AAGGPALIEVKT 168
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
20-178 |
8.64e-44 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 152.69 E-value: 8.64e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 20 DLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQE 99
Cdd:cd07035 1 DALVEALKAEGVDHVFGVPGGAILPLLDALARSGIRYILVRHEQGAVGMADGYARATGKPGVVLVTSGPGLTNAVTGLAN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 100 AYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEIPQ 178
Cdd:cd07035 81 AYLDSIPLLVITGQRPTAGEGRGA----FQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLPK 155
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
20-534 |
2.24e-43 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 163.23 E-value: 2.24e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 20 DLVVETLEALGAKTVFGIPGQHALGLFDAM-GRGNLHFVSSRIENNSAFAADGYSRAT-GEVGVLFLSTGPGALTSLAGL 97
Cdd:PRK11269 8 DAAVLVLEKEGVTTAFGVPGAAINPFYSAMrKHGGIRHILARHVEGASHMAEGYTRATaGNIGVCIGTSGPAGTDMITGL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 98 QEAYATGVPMVVVASQIPLeglgARrkgmLHQLD----DQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVW 173
Cdd:PRK11269 88 YSASADSIPILCITGQAPR----AR----LHKEDfqavDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 174 LEIPQNVLLDPIMVPPVEDA---LAEAADNPPRIElvrEAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVIC 250
Cdd:PRK11269 160 IDLPFDVQVAEIEFDPDTYEplpVYKPAATRAQIE---KALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 251 TPGGNGAFPWNHEL-----SLQAwiEDRYMTDVLEDADVLVVIGSSLGEV-TSNYFTFEPRGRIIQIDAEP----RVLEs 320
Cdd:PRK11269 237 TLMGWGAIPDDHPLmagmvGLQT--SHRYGNATLLASDFVLGIGNRWANRhTGSVEVYTKGRKFVHVDIEPtqigRVFG- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 321 nrPGLGIRADAGQALAALDEALQPGRAAA--PDWHGATPEslVQESLAKVRARLESQDLG-KELKFMADIREAVPADmqT 397
Cdd:PRK11269 314 --PDLGIVSDAKAALELLVEVAREWKAAGrlPDRSAWVAD--CQERKRTLLRKTHFDNVPiKPQRVYEEMNKAFGRD--T 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 398 FWDMTIAAYWGWScwdarqGQFHSAQG---------AGGLGFAFPGAIGAAVgletqGRPGR-VLAVSGDGSSMYSIAEL 467
Cdd:PRK11269 388 CYVSTIGLSQIAA------AQFLHVYKprhwincgqAGPLGWTIPAALGVRA-----ADPDRnVVALSGDYDFQFLIEEL 456
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 468 ATAKQHNVPVTWLIVDDGGYGILR--------EYMVG-AFGKATATELAR--PDFVRLAESFGIPATRV-APEDVGDAL 534
Cdd:PRK11269 457 AVGAQFNLPYIHVLVNNAYLGLIRqaqrafdmDYCVQlAFENINSPELNGygVDHVKVAEGLGCKAIRVfKPEDIAPAL 535
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
16-552 |
3.77e-43 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 162.09 E-value: 3.77e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 16 RNGGDLVVETLEALGAKTVFGIPG------QHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPG 89
Cdd:PRK08327 7 YTAAELFLELLKELGVDYIFINSGtdyppiIEAKARARAAGRPLPEFVICPHEIVAISMAHGYALVTGKPQAVMVHVDVG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 90 ALTSLAGLQEAYATGVPMVVVASQIPL--EG-LGAR--RKGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEA 164
Cdd:PRK08327 87 TANALGGVHNAARSRIPVLVFAGRSPYteEGeLGSRntRIHWTQEMRDQGGLVREYVKWDYEIRRGDQIGEVVARAIQIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 165 ISSPQGPVWLEIPQNVLLDPimvppVEDALAEAADNP------PRIELVREAVKWLEAARRPAIIAGGGTRRGKAEKSLL 238
Cdd:PRK08327 167 MSEPKGPVYLTLPREVLAEE-----VPEVKADAGRQMapappaPDPEDIARAAEMLAAAERPVIITWRAGRTAEGFASLR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 239 SIAEKLRAPVICTPGGNGAFPWNHELSLQAWIEdrymtDVLEDADVLVVIGSslgEVTsnYFTFE----PRGRIIQIDAE 314
Cdd:PRK08327 242 RLAEELAIPVVEYAGEVVNYPSDHPLHLGPDPR-----ADLAEADLVLVVDS---DVP--WIPKKirpdADARVIQIDVD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 315 P---RV-LESNRPGLGIRADAGQALAALDEALQPgRAAAPDWHGATPESLVQESLAKVR-ARLESQDLGKELKFM----- 384
Cdd:PRK08327 312 PlksRIpLWGFPCDLCIQADTSTALDQLEERLKS-LASAERRRARRRRAAVRELRIRQEaAKRAEIERLKDRGPItpayl 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 385 -ADIREAVPADMQTFWDMTIAAywgWSCWDARQGQFHSAQGAGGLGFAFPGAIGAAvgLETQGRPgrVLAVSGDGSSMYS 463
Cdd:PRK08327 391 sYCLGEVADEYDAIVTEYPFVP---RQARLNKPGSYFGDGSAGGLGWALGAALGAK--LATPDRL--VIATVGDGSFIFG 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 464 I--AELATAKQHNVPVTWLIVDDGGYGILREYMVGAF--GKATATE-------LARPDFVRLAESFGIPATRVA-PEDVG 531
Cdd:PRK08327 464 VpeAAHWVAERYGLPVLVVVFNNGGWLAVKEAVLEVYpeGYAARKGtfpgtdfDPRPDFAKIAEAFGGYGERVEdPEELK 543
|
570 580
....*....|....*....|...
gi 1718153936 532 DALKAGFA--GDGPNVVVVETLL 552
Cdd:PRK08327 544 GALRRALAavRKGRRSAVLDVIV 566
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
23-535 |
1.76e-42 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 160.55 E-value: 1.76e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 23 VETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQEAYA 102
Cdd:PRK07525 13 VETLQAHGITHAFGIIGSAFMDASDLFPPAGIRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQNGPGITNFVTAVATAYW 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 103 TGVPMVVVASQIPLEGLGarRKGMlhQLDDQKASAANVTKSQRLIQHASGIPS----AIQDAWTEaisspQGPVWLEIPQ 178
Cdd:PRK07525 93 AHTPVVLVTPQAGTKTIG--QGGF--QEAEQMPMFEDMTKYQEEVRDPSRMAEvlnrVFDKAKRE-----SGPAQINIPR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 179 NVLLDPImvppvEDALAEaadnPPRIE-------LVREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICT 251
Cdd:PRK07525 164 DYFYGVI-----DVEIPQ----PVRLErgaggeqSLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 252 PGGNGAFPWNHELSL--------QAWIEdrymtdVLEDADVLVVIGSSLGEVTS------NYFtfePR-GRIIQIDAEPR 316
Cdd:PRK07525 235 YLHNDAFPGSHPLWVgplgyngsKAAME------LIAKADVVLALGTRLNPFGTlpqygiDYW---PKdAKIIQVDINPD 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 317 VLESNRP-GLGIRADAGQALAALDEALQP------GRAAAPDWHGATPESLVQE------------SLAKVRARLESQDL 377
Cdd:PRK07525 306 RIGLTKKvSVGICGDAKAVARELLARLAErlagdaGREERKALIAAEKSAWEQElsswdhedddpgTDWNEEARARKPDY 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 378 GKELKFMADIREAVPADMQTFWDMTIAAYWGWSCWDARQGQFHSAQGA-GGLGFAFPGAIGAAVGletqgRPGR-VLAVS 455
Cdd:PRK07525 386 MHPRQALREIQKALPEDAIVSTDIGNNCSIANSYLRFEKGRKYLAPGSfGNCGYAFPAIIGAKIA-----CPDRpVVGFA 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 456 GDGSSMYSIAELATAKQHNVPVTWLivddggygILREYMVGAFGKAT---------ATEL-ARPDFVRLAESFGIPATRV 525
Cdd:PRK07525 461 GDGAWGISMNEVMTAVRHNWPVTAV--------VFRNYQWGAEKKNQvdfynnrfvGTELdNNVSYAGIAEAMGAEGVVV 532
|
570
....*....|.
gi 1718153936 526 -APEDVGDALK 535
Cdd:PRK07525 533 dTQEELGPALK 543
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
23-543 |
9.34e-41 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 155.63 E-value: 9.34e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 23 VETLEALGAKTVFGIPGQHALGLFDAM----GRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQ 98
Cdd:CHL00099 17 IDSLVRHGVKHIFGYPGGAILPIYDELyaweKKGLIKHILVRHEQGAAHAADGYARSTGKVGVCFATSGPGATNLVTGIA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 99 EAYATGVPMVVVASQIPLEGLGARRkgmlHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSPQGPVWLEIPQ 178
Cdd:CHL00099 97 TAQMDSVPLLVITGQVGRAFIGTDA----FQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGPVLIDIPK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 179 NVLLDPIMVPPVE--DALAEAADNPPRIEL----VREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTP 252
Cdd:CHL00099 173 DVGLEKFDYYPPEpgNTIIKILGCRPIYKPtikrIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVTTTL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 253 GGNGAFPWNHELSL-------QAwiedrYMTDVLEDADVLVVIGSSLGE-VTSNYFTFEPRGRIIQIDAEPRVLESNR-P 323
Cdd:CHL00099 253 MGKGIFDEDHPLCLgmlgmhgTA-----YANFAVSECDLLIALGARFDDrVTGKLDEFACNAQVIHIDIDPAEIGKNRiP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 324 GLGIRADAGQALAAL------------DEALQPGRAAAPDWHGATPESLVQESLAkvrarLESQDLGKELKFMADireav 391
Cdd:CHL00099 328 QVAIVGDVKKVLQELlellknspnlleSEQTQAWRERINRWRKEYPLLIPKPSTS-----LSPQEVINEISQLAP----- 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 392 padmQTFWDMTIAAYWGWSCWDARQGQFH--SAQGAGGLGFAFPGAIGAAVGLETQgrpgRVLAVSGDGSSMYSIAELAT 469
Cdd:CHL00099 398 ----DAYFTTDVGQHQMWAAQFLKCKPRKwlSSAGLGTMGYGLPAAIGAQIAHPNE----LVICISGDASFQMNLQELGT 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 470 AKQHNVPVTWLIVDDGGYGILREYMVGAFGK----ATATELArPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGP 543
Cdd:CHL00099 470 IAQYNLPIKIIIINNKWQGMVRQWQQAFYGEryshSNMEEGA-PDFVKLAEAYGIKGLRIkSRKDLKSSLKEALDYDGP 547
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
18-548 |
3.92e-38 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 148.23 E-value: 3.92e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 18 GGDLVVETLEALGAKTVFGIPGQHALGLFDAM--GRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:PRK08611 6 AGEALVKLLQDWGIDHVYGIPGDSIDAVVDALrkEQDKIKFIQVRHEEVAALAAAAYAKLTGKIGVCLSIGGPGAIHLLN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGA---RRKGMLHQLDDqkasaanVTKSQRLIQHASGIP----SAIQDAWTEaissp 168
Cdd:PRK08611 86 GLYDAKMDHVPVLALAGQVTSDLLGTdffQEVNLEKMFED-------VAVYNHQIMSAENLPeivnQAIRTAYEK----- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 169 QGPVWLEIPQNVLLDPIMVPPVEDALAEAADNP-PRIELVREAVKWLEAARRPAIIAGGGTRRGKAEksLLSIAEKLRAP 247
Cdd:PRK08611 154 KGVAVLTIPDDLPAQKIKDTTNKTVDTFRPTVPsPKPKDIKKAAKLINKAKKPVILAGLGAKHAKEE--LLAFAEKAKIP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 248 VICTPGGNGAFPWNHELSL----QAWIEDRYMTdvLEDADVLVVIGSSLgevtsNYFTFEPRG-RIIQIDAEPRVLESNR 322
Cdd:PRK08611 232 IIHTLPAKGIIPDDHPYSLgnlgKIGTKPAYEA--MQEADLLIMVGTNY-----PYVDYLPKKaKAIQIDTDPANIGKRY 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 323 P-GLGIRADAGQALAALDE--ALQPGRA--AAPDWHGATPESLVQESLAKVRARLESQDLgkelkfMADIREAVPADMQT 397
Cdd:PRK08611 305 PvNVGLVGDAKKALHQLTEniKHVEDRRflEACQENMAKWWKWMEEDENNASTPIKPERV------MAAIQKIADDDAVL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 398 FWDMTIAAYWGwscwdAR------QGQFHSAQGAGGLGFAFPGAIGAAVGLetqgrPGR-VLAVSGDGSSMYSIAELATA 470
Cdd:PRK08611 379 SVDVGTVTVWS-----ARylnlgtNQKFIISSWLGTMGCGLPGAIAAKIAF-----PDRqAIAICGDGGFSMVMQDFVTA 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 471 KQHNVPVTWLIVDDGGYGILrEYMVGAFGKAT-ATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVV 548
Cdd:PRK08611 449 VKYKLPIVVVVLNNQQLAFI-KYEQQAAGELEyAIDLSDMDYAKFAEACGGKGYRVeKAEELDPAFEEALAQDKPVIIDV 527
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
20-550 |
5.66e-37 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 144.20 E-value: 5.66e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 20 DLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLAGLQE 99
Cdd:PRK06457 6 EVIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKSKVKYVQVRHEEGAALAASVEAKITGKPSACMGTSGPGSIHLLNGLYD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 100 AYATGVPMVVVASQIPLEGLGA---RRKGMLHQLDDqkASAANvtksQRLI--QHASGIpsaIQDAWTEAISSpQGPVWL 174
Cdd:PRK06457 86 AKMDHAPVIALTGQVESDMIGHdyfQEVNLTKLFDD--VAVFN----QILInpENAEYI---IRRAIREAISK-RGVAHI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 175 EIPQNVLLDPIMVPPVEDALAEAADNPPRIELVREAVkwlEAARRPAIIAGGGTrRGKAEKsLLSIAEKLRAPVICTPGG 254
Cdd:PRK06457 156 NLPVDILRKSSEYKGSKNTEVGKVKYSIDFSRAKELI---KESEKPVLLIGGGT-RGLGKE-INRFAEKIGAPIIYTLNG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 255 NGAFPWNHELSLQ--AWIEDRYMTDVLEDADVLVVIGSSLgevtsNYFTFEPR-GRIIQIDAEPrvleSNrpgLGIRADA 331
Cdd:PRK06457 231 KGILPDLDPKVMGgiGLLGTKPSIEAMDKADLLIMLGTSF-----PYVNFLNKsAKVIQVDIDN----SN---IGKRLDV 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 332 GQALAA-LDEALQPGRAAAPDWHGATPESLVQESLAKVRARLESQDLGKELKFMA-DIREAVPADMQTFWDMTIAAYWGW 409
Cdd:PRK06457 299 DLSYPIpVAEFLNIDIEEKSDKFYEELKGKKEDWLDSISKQENSLDKPMKPQRVAyIVSQKCKKDAVIVTDTGNVTMWTA 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 410 SCWDARQGQ-FHSAQGAGGLGFAFPGAIGAAVgleTQGRPGRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYG 488
Cdd:PRK06457 379 RHFRASGEQtFIFSAWLGSMGIGVPGSVGASF---AVENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLG 455
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1718153936 489 ILR-EYMVGAFGKaTATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNV--VVVET 550
Cdd:PRK06457 456 MIKfEQEVMGYPE-WGVDLYNPDFTKIAESIGFKGFRLEePKEAEEIIEEFLNTKGPAVldAIVDP 520
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
15-550 |
7.72e-37 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 144.36 E-value: 7.72e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK06546 2 AKTVAEQLVEQLVAAGVKRIYGIVGDSLNPIVDAVRRtGGIEWVHVRHEEAAAFAAAAEAQLTGKLAVCAGSCGPGNLHL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGArrkGMLHQlddqkasaanvTKSQRLIQHASGipsaiqdaWTEAISSP-QGPV 172
Cdd:PRK06546 82 INGLYDAHRSGAPVLAIASHIPSAQIGS---GFFQE-----------THPDRLFVECSG--------YCEMVSSAeQAPR 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 173 WLEIP-QNVLLDP----IMVP------PVEDALAEAADNPPRIEL------VREAVKWLEAARRPAIIAGGGTRRGKAEk 235
Cdd:PRK06546 140 VLHSAiQHAVAGGgvsvVTLPgdiadePAPEGFAPSVISPRRPTVvpdpaeVRALADAINEAKKVTLFAGAGVRGAHAE- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 236 sLLSIAEKLRAPVictpggngafpwNHELSLQAWIE-----DRYMTDVL---------EDADVLVVIGSSLgevtsNYFT 301
Cdd:PRK06546 219 -VLALAEKIKAPV------------GHSLRGKEWIQydnpfDVGMSGLLgygaaheamHEADLLILLGTDF-----PYDQ 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 302 FEPRGRIIQIDAEPRVL-ESNRPGLGIRADAGQALAALDEALQPgraaapdwhgATPESLVQESLAKVRARLE------S 374
Cdd:PRK06546 281 FLPDVRTAQVDIDPEHLgRRTRVDLAVHGDVAETIRALLPLVKE----------KTDRRFLDRMLKKHARKLEkvvgayT 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 375 QDLGKEL----KFMADIREAVPADmqtfwDMTIAAYWGW-SCWDARQ----------GQF-HsaqgaGGLGFAFPGAIGA 438
Cdd:PRK06546 351 RKVEKHTpihpEYVASILDELAAD-----DAVFTVDTGMcNVWAARYitpngrrrviGSFrH-----GSMANALPHAIGA 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 439 AVgletqGRPGR-VLAVSGDGS-SMYsIAELATAKQHNVPVTWLIVDDGGYGILR-EYMVG---AFGkataTELARPDFV 512
Cdd:PRK06546 421 QL-----ADPGRqVISMSGDGGlSML-LGELLTVKLYDLPVKVVVFNNSTLGMVKlEMLVDglpDFG----TDHPPVDYA 490
|
570 580 590
....*....|....*....|....*....|....*....
gi 1718153936 513 RLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:PRK06546 491 AIAAALGIHAVRVEdPKDVRGALREAFAHPGPALVDVVT 529
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
15-550 |
5.45e-35 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 138.97 E-value: 5.45e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK09124 2 KQTVADYIAKTLEQAGVKRIWGVTGDSLNGLSDSLRRmGTIEWMHTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLGArrkGMLHQlddqkasaanvTKSQRL----------IQHASGIPSAIQDAWTE 163
Cdd:PRK09124 82 INGLFDCHRNHVPVLAIAAHIPSSEIGS---GYFQE-----------THPQELfrecshycelVSNPEQLPRVLAIAMRK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 164 AISSpQGPVWLEIPQNVLLDPIMVPPVEDALAEAAD--NPPRIELVREAvKWLEAARRPAIIAGGGTRRGKAEksLLSIA 241
Cdd:PRK09124 148 AILN-RGVAVVVLPGDVALKPAPERATPHWYHAPQPvvTPAEEELRKLA-ALLNGSSNITLLCGSGCAGAHDE--LVALA 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 242 EKLRAPVIctpggngafpwnHELSLQAWIE-----DRYMT---------DVLEDADVLVVIGSSLgevtsNYFTFEP-RG 306
Cdd:PRK09124 224 ETLKAPIV------------HALRGKEHVEydnpyDVGMTgligfssgyHAMMNCDTLLMLGTDF-----PYRQFYPtDA 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 307 RIIQIDAEPRVLESNRP-GLGIRADAGQALAALDEALQPGR-----AAAPDWHGATPESLvqESLAK---VRARLESQDL 377
Cdd:PRK09124 287 KIIQIDINPGSLGRRSPvDLGLVGDVKATLAALLPLLEEKTdrkflDKALEHYRKARKGL--DDLAVpsdGGKPIHPQYL 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 378 GKELKFMADIREAVPADMQTfwdMTIaaywgwscWDAR------QGQFHSAQGAGGLGFAFPGAIGAAVGletqgRPGR- 450
Cdd:PRK09124 365 ARQISEFAADDAIFTCDVGT---PTV--------WAARylkmngKRRLLGSFNHGSMANAMPQALGAQAA-----HPGRq 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 451 VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATELARPDFVRLAESFGIPATRVA-PED 529
Cdd:PRK09124 429 VVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTDLHNPDFAAIAEACGITGIRVEkASE 508
|
570 580
....*....|....*....|.
gi 1718153936 530 VGDALKAGFAGDGPNVVVVET 550
Cdd:PRK09124 509 LDGALQRAFAHDGPALVDVVT 529
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
207-338 |
2.64e-32 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 120.75 E-value: 2.64e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 207 VREAVKWLEAARRPAIIAGGGTRRGKAEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSLQAW--IEDRYMTDVLEDADV 284
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLgmHGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1718153936 285 LVVIGSSLGE--VTSNYFTFEPRGRIIQIDAEPRVLESNRPG-LGIRADAGQALAAL 338
Cdd:pfam00205 81 VLAVGARFDDirTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVdVPIVGDAKETLEAL 137
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
407-548 |
3.76e-32 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 121.15 E-value: 3.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 407 WGWSCWDARQ-GQFHSAQGAGGLGFAFPGAIGAAVGletqgRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDD 484
Cdd:pfam02775 8 WAAQYYRFRPpRRYLTSGGLGTMGYGLPAAIGAKLA-----RPDRpVVAIAGDGGFQMNLQELATAVRYNLPITVVVLNN 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 485 GGYGILREYMVGAFGKATATE----LARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPNVVVV 548
Cdd:pfam02775 83 GGYGMTRGQQTPFGGGRYSGPsgkiLPPVDFAKLAEAYGAKGARVeSPEELEEALKEALEHDGPALIDV 151
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
413-550 |
8.35e-31 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 118.08 E-value: 8.35e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 413 DARQGQFHSAqGAGGLGFAFPGAIGAAVGLetqgRPGRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILRE 492
Cdd:cd02002 37 LTRPGSYFTL-RGGGLGWGLPAAVGAALAN----PDRKVVAIIGDGSFMYTIQALWTAARYGLPVTVVILNNRGYGALRS 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1718153936 493 YM--VGAFGKATATELA------RPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:cd02002 112 FLkrVGPEGPGENAPDGldlldpGIDFAAIAKAFGVEAERVEtPEELDEALREALAEGGPALIEVVV 178
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
7-546 |
1.13e-30 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 126.25 E-value: 1.13e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 7 PAPAEGRGARNGGDLVVETLEALGAKTVFGIPGqhaLGLFD----AMGRGnLHFVSSRIENNS--AFAADGYsrATGEVG 80
Cdd:PRK09259 1 TAMSDQLQLTDGFHLVIDALKLNGIDTIYGVVG---IPITDlarlAQAEG-IRYIGFRHEQSAgnAAAAAGF--LTQKPG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 81 VLFLSTGPGALTSLAGLQEAYATGVPMVVVAsqipleGLGARRKGMLHQLD----DQKASAANVTKSQRLIQHASGIPSA 156
Cdd:PRK09259 75 VCLTVSAPGFLNGLTALANATTNCFPMIMIS------GSSEREIVDLQQGDyeelDQLNAAKPFCKAAFRVNRAEDIGIG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 157 IQDAWTEAISSPQGPVWLEIPQNVLLDPIMVPPVEDALAEAADNPPR----IELVREAVKWLEAARRPAIIAGGGTRRGK 232
Cdd:PRK09259 149 VARAIRTAVSGRPGGVYLDLPAKVLAQTMDADEALTSLVKVVDPAPAqlpaPEAVDRALDLLKKAKRPLIILGKGAAYAQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 233 AEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSLQAwieDRYMtdVLEDADVLVVIGSSLGEVTSN--YFTFEPRGRIIQ 310
Cdd:PRK09259 229 ADEQIREFVEKTGIPFLPMSMAKGLLPDTHPQSAAA---ARSL--ALANADVVLLVGARLNWLLSHgkGKTWGADKKFIQ 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 311 IDAEPRVLESNRPglgIRA----DAGQALAALDEALQPGRAAAP-DWHGATPESlVQESLAKVRARLESQDlgKELKFMA 385
Cdd:PRK09259 304 IDIEPQEIDSNRP---IAApvvgDIGSVMQALLAGLKQNTFKAPaEWLDALAER-KEKNAAKMAEKLSTDT--QPMNFYN 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 386 DIReAVPADMQTFWDMTIAAYwGWSCWDARQGQFHSAQ----------GAGGLGFAFpgAIGAAVglETqGRPgrVLAVS 455
Cdd:PRK09259 378 ALG-AIRDVLKENPDIYLVNE-GANTLDLARNIIDMYKprhrldcgtwGVMGIGMGY--AIAAAV--ET-GKP--VVAIE 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 456 GDGSSMYSIAELATAKQHNVPVTWLIVDDGgyGILREYMVGAFGK---ATATELARPDFVRLAESFGIPATRVA-PEDVG 531
Cdd:PRK09259 449 GDSAFGFSGMEVETICRYNLPVTVVIFNNG--GIYRGDDVNLSGAgdpSPTVLVHHARYDKMMEAFGGVGYNVTtPDELR 526
|
570
....*....|....*
gi 1718153936 532 DALKAGFAGDGPNVV 546
Cdd:PRK09259 527 HALTEAIASGKPTLI 541
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
17-180 |
5.22e-27 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 106.87 E-value: 5.22e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR-GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTSLA 95
Cdd:cd07039 1 TVADVIVETLENWGVKRVYGIPGDSINGLMDALRReGKIEFIQVRHEEAAAFAASAEAKLTGKLGVCLGSSGPGAIHLLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 96 GLQEAYATGVPMVVVASQIPLEGLGarrkGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSpQGPVWLE 175
Cdd:cd07039 81 GLYDAKRDRAPVLAIAGQVPTDELG----TDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTAIAK-RGVAVLI 155
|
....*
gi 1718153936 176 IPQNV 180
Cdd:cd07039 156 LPGDV 160
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
381-548 |
4.81e-26 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 104.68 E-value: 4.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 381 LKFMADIREAVPADMQTFWDMTIAAYW---GWSCWDARQGQFHSAQGAggLGFAFPGAIGAAVGletqgRPGR-VLAVSG 456
Cdd:cd02010 2 QRIVHDLRAVMGDDDIVLLDVGAHKIWmarYYRTYAPNTCLISNGLAT--MGVALPGAIGAKLV-----YPDRkVVAVSG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 457 DGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATELARPDFVRLAESFGIPATRV-APEDVGDALK 535
Cdd:cd02010 75 DGGFMMNSQELETAVRLKIPLVVLIWNDNGYGLIKWKQEKEYGRDSGVDFGNPDFVKYAESFGAKGYRIeSADDLLPVLE 154
|
170
....*....|...
gi 1718153936 536 AGFAGDGPNVVVV 548
Cdd:cd02010 155 RALAADGVHVIDC 167
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
415-549 |
1.15e-25 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 104.12 E-value: 1.15e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 415 RQGQFHSAQGAGGLGFAFPGAIGAAVGletqgRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREY 493
Cdd:cd02015 39 KPRSWLTSGGLGTMGFGLPAAIGAKVA-----RPDKtVICIDGDGSFQMNIQELATAAQYNLPVKIVILNNGSLGMVRQW 113
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1718153936 494 MVGAFGK--ATATELARPDFVRLAESFGIPATRV-APEDVGDALKAGFAGDGPnvVVVE 549
Cdd:cd02015 114 QELFYEGrySHTTLDSNPDFVKLAEAYGIKGLRVeKPEELEAALKEALASDGP--VLLD 170
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
17-548 |
9.70e-24 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 104.93 E-value: 9.70e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPG---QH-------------ALGLFD--AMGrgnlhfvssriennsafAADGYSRATGE 78
Cdd:PRK07586 2 NGAESLVRTLVDGGVDVCFANPGtseMHfvaaldrvpgmrcVLGLFEgvATG-----------------AADGYARMAGK 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 79 VGVLFLSTGPGALTSLAGLQEAYATGVPMVVVASQ---------IPLEGlgarrkgmlhqldDQKASAANVTKSQRLIQH 149
Cdd:PRK07586 65 PAATLLHLGPGLANGLANLHNARRARTPIVNIVGDhatyhrkydAPLTS-------------DIEALARPVSGWVRRSES 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 150 ASGIPSAIQDAWTEAISSPQGPVWLEIPQNVLLDPImvPPVEDALAEAADNPPRIELVREAVKWLEAARRPAIIAGGGTR 229
Cdd:PRK07586 132 AADVAADAAAAVAAARGAPGQVATLILPADVAWSEG--GPPAPPPPAPAPAAVDPAAVEAAAAALRSGEPTVLLLGGRAL 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 230 RGKAEKSLLSIAEKLRAPVIC------TPGGNGAF-----PWNHELSLQAwiedrymtdvLEDADVLVVIGSslgEVTSN 298
Cdd:PRK07586 210 RERGLAAAARIAAATGARLLAetfparMERGAGRPaverlPYFAEQALAQ----------LAGVRHLVLVGA---KAPVA 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 299 YFTFEPR-GRIIQIDAEPRVLEsnrpglGIRADAGQALAALDEALQPGRAAAPDWHGATPE----SLVQESLAKVRARLe 373
Cdd:PRK07586 277 FFAYPGKpSRLVPEGCEVHTLA------GPGEDAAAALEALADALGAKPAAPPLAAPARPPlptgALTPEAIAQVIAAL- 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 374 sqdlgkelkfMAD----IREAVPADMQtFWDMTIAAywgwscwdARQGQFHSAQGAggLGFAFPGAIGAAVGLetqgrPG 449
Cdd:PRK07586 350 ----------LPEnaivVDESITSGRG-FFPATAGA--------APHDWLTLTGGA--IGQGLPLATGAAVAC-----PD 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 450 R-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYM--VGAFGKATA----TELARP--DFVRLAESFGI 520
Cdd:PRK07586 404 RkVLALQGDGSAMYTIQALWTQARENLDVTTVIFANRAYAILRGELarVGAGNPGPRaldmLDLDDPdlDWVALAEGMGV 483
|
570 580
....*....|....*....|....*....
gi 1718153936 521 PATRVA-PEDVGDALKAGFAGDGPNVVVV 548
Cdd:PRK07586 484 PARRVTtAEEFADALAAALAEPGPHLIEA 512
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
15-550 |
1.33e-23 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 104.99 E-value: 1.33e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 15 ARNGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGR--GNLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALT 92
Cdd:PRK08273 2 SQTVADFILERLREWGVRRVFGYPGDGINGLLGALGRadDKPEFVQARHEEMAAFMAVAHAKFTGEVGVCLATSGPGAIH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 93 SLAGLQEAYATGVPMVVVASQIPLEGLGA--RRKGMLHQLDDQKASAANVTKSqrliqHASGIPSAIQDAWTEAISSpQG 170
Cdd:PRK08273 82 LLNGLYDAKLDHVPVVAIVGQQARAALGGhyQQEVDLQSLFKDVAGAFVQMVT-----VPEQLRHLVDRAVRTALAE-RT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 171 PVWLEIPQNVLLDPIMVPPVEDALAEAA--DNPPRI----ELVREAVKWLEAARRPAIIAGGGTRRGKAEksLLSIAEKL 244
Cdd:PRK08273 156 VTAVILPNDVQELEYEPPPHAHGTVHSGvgYTRPRVvpydEDLRRAAEVLNAGRKVAILVGAGALGATDE--VIAVAERL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 245 RAPVICTPGGNGAFPwnHELslqawiedRYMT------------DVLEDADVLVVIGSSlgevtSNYFTFEPR---GRII 309
Cdd:PRK08273 234 GAGVAKALLGKAALP--DDL--------PWVTgsigllgtkpsyELMRECDTLLMVGSS-----FPYSEFLPKegqARGV 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 310 QIDAEPRVLeSNR-P-GLGIRADAGQALAALDEALQPGRAAApdWHgATPESLV---QESLAKvRARLESQDLGKELKFm 384
Cdd:PRK08273 299 QIDIDGRML-GLRyPmEVNLVGDAAETLRALLPLLERKKDRS--WR-ERIEKWVarwWETLEA-RAMVPADPVNPQRVF- 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 385 ADIREAVPADMQTFWDMTIAAYWGWSCWDARQGQFHSAqgAGGL---GFAFPGAIGAAvgLETQGRPgrVLAVSGDGS-S 460
Cdd:PRK08273 373 WELSPRLPDNAILTADSGSCANWYARDLRMRRGMMASL--SGTLatmGPAVPYAIAAK--FAHPDRP--VIALVGDGAmQ 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 461 MYSIAELATAKQ---------------HN---VPVTWLivddggygiLREyMVGAfGKATATElARPDF--VRLAESFGI 520
Cdd:PRK08273 447 MNGMAELITVAKywrqwsdprlivlvlNNrdlNQVTWE---------QRV-MEGD-PKFEASQ-DLPDVpyARFAELLGL 514
|
570 580 590
....*....|....*....|....*....|.
gi 1718153936 521 PATRV-APEDVGDALKAGFAGDGPNVVVVET 550
Cdd:PRK08273 515 KGIRVdDPEQLGAAWDEALAADRPVVLEVKT 545
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
26-177 |
1.40e-22 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 94.48 E-value: 1.40e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 26 LEALGAKTVFGIPGQHALGLFDA-MGRGNLHFVSSRIENNSAFAADGYSRATGeVGVLFLSTGPGALTSLAGLQEAYATG 104
Cdd:cd07038 7 LKQLGVKHVFGVPGDYNLPLLDAiEENPGLRWVGNCNELNAGYAADGYARVKG-LGALVTTYGVGELSALNGIAGAYAEH 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 105 VPmVVVASQIPleGLGARRKGML--HQL-----DDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSpQGPVWLEIP 177
Cdd:cd07038 86 VP-VVHIVGAP--STKAQASGLLlhHTLgdgdfDVFLKMFEEITCAAARLTDPENAAEEIDRVLRTALRE-SRPVYIEIP 161
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
1-489 |
1.26e-19 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 92.46 E-value: 1.26e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 1 MTELAAPAPAEGRGARNGGDLVVETLEaLGAKTVFGIPGQHALGLFDA-MGRGNLHFVSSRIENNSAFAADGYSRATGeV 79
Cdd:PLN02573 2 SSAPKPATPVSSSDATLGRHLARRLVE-IGVTDVFSVPGDFNLTLLDHlIAEPGLNLIGCCNELNAGYAADGYARARG-V 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 80 G---VLFLSTGPGALTSLAGlqeAYATGVPMVVVASQIPLEGLGARRkgMLHQ---LDD--QKASA-ANVTKSQRLIQHA 150
Cdd:PLN02573 80 GacvVTFTVGGLSVLNAIAG---AYSENLPVICIVGGPNSNDYGTNR--ILHHtigLPDfsQELRCfQTVTCYQAVINNL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 151 SGIPSAIQDAWTEAISSPQgPVWLEIPQNVLLDP---IMVPPVEDALAEAADNPPRIELVREA-VKWLEAARRPAIIAGG 226
Cdd:PLN02573 155 EDAHELIDTAISTALKESK-PVYISVSCNLAAIPhptFSREPVPFFLTPRLSNKMSLEAAVEAaAEFLNKAVKPVLVGGP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 227 GTRRGKAEKSLLSIAEKLRAPVICTPGGNGAFPWNHELSLQA-W--IEDRYMTDVLEDADVLVVIG------SSLGevts 297
Cdd:PLN02573 234 KLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGTyWgaVSTPFCAEIVESADAYLFAGpifndySSVG---- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 298 nYFTFEPRGRIIQIDAEpRVLESNRPGLG--IRADagqALAALDEALQPGRAAAPDWH------GATPESLVQESLaKVR 369
Cdd:PLN02573 310 -YSLLLKKEKAIIVQPD-RVTIGNGPAFGcvLMKD---FLEALAKRVKKNTTAYENYKrifvpeGEPLKSEPGEPL-RVN 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 370 ArlesqdLGKELKFMADIREAVPADMQTFWdmtiaaywgWSCWDARQGQfhsaqgagGLGFAFP---GAIGAAVGLE--- 443
Cdd:PLN02573 384 V------LFKHIQKMLSGDTAVIAETGDSW---------FNCQKLKLPE--------GCGYEFQmqyGSIGWSVGATlgy 440
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 1718153936 444 TQGRPG-RVLAVSGDGSSMYSIAELATA-KQHNVPVTWLIvDDGGYGI 489
Cdd:PLN02573 441 AQAAPDkRVIACIGDGSFQVTAQDVSTMiRCGQKSIIFLI-NNGGYTI 487
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
404-550 |
4.44e-17 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 79.11 E-value: 4.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 404 AAYWGWSCWDARQGQFHSAQGA-GGLGFAFPGAIGAAVGLetqgrPGR-VLAVSGDGS-SMySIAELATAKQHNVPVTWL 480
Cdd:cd02014 28 VTVWAARHLRMNGKQRFILSGLlATMGNGLPGAIAAKLAY-----PDRqVIALSGDGGfAM-LMGDLITAVKYNLPVIVV 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1718153936 481 IVDDGGYG-ILREYMVGAFGKaTATELARPDFVRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:cd02014 102 VFNNSDLGfIKWEQEVMGQPE-FGVDLPNPDFAKIAEAMGIKGIRVEdPDELEAALDEALAADGPVVIDVVT 172
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
381-547 |
7.33e-16 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 75.65 E-value: 7.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 381 LKFMADIREAVPADMQTFWDMTIAAYWGWSCWDARQ-GQFHSAQGAGGLGFAFPGAIGAAvgLETQGRpgRVLAVSGDGS 459
Cdd:cd02004 2 YRVLHELQEALPDDAIIVSDGGNTMDWARYILRPRKpRHRLDAGTFGTLGVGLGYAIAAA--LARPDK--RVVLVEGDGA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 460 SMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAF--GKATATELARPDFVRLAESFGIPATRVA-PEDVGDALKA 536
Cdd:cd02004 78 FGFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQLSYglGLPVTTLLPDTRYDLVAEAFGGKGELVTtPEELKPALKR 157
|
170
....*....|....
gi 1718153936 537 GFAGDGP---NVVV 547
Cdd:cd02004 158 ALASGKPaliNVII 171
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
17-546 |
2.73e-14 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 75.29 E-value: 2.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 17 NGGDLVVETLEALGAKTVFGIPG---QHALGLFDAMGRgnLHFVSSRIENNSAFAADGYSRATGEVGVLFLSTGPGALTS 93
Cdd:PRK12474 6 NGADSVVDTLLNCGVEVCFANPGtseMHFVAALDRVPR--MRPVLCLFEGVVTGAADGYGRIAGKPAVTLLHLGPGLANG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 94 LAGLQEAYATGVPMVVVASQIPLEGLgarrkgmlhQLDDQKAS-----AANVTKSQRLIQHASGIPSAIQDAWTEAISSP 168
Cdd:PRK12474 84 LANLHNARRAASPIVNIVGDHAVEHL---------QYDAPLTSdidgfARPVSRWVHRSASAGAVDSDVARAVQAAQSAP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 169 QGPVWLEIPQNVLLDPimvppvEDALAEAADNPPRIELVREAVKWLEAA----RRPAIIAGGGTRRGKAEKSLLSIAEKL 244
Cdd:PRK12474 155 GGIATLIMPADVAWNE------AAYAAQPLRGIGPAPVAAETVERIAALlrngKKSALLLRGSALRGAPLEAAGRIQAKT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 245 RAPVIC-TPGGNGAF----------PWNHELslqawiedryMTDVLEDADVLVVIGSSlgevtsnyftfEPrgriIQIDA 313
Cdd:PRK12474 229 GVRLYCdTFAPRIERgagrvpieriPYFHEQ----------ITAFLKDVEQLVLVGAK-----------PP----VSFFA 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 314 EPrvlesNRPGLGIRA------------DAGQALAALDEALQPGRAAAPDWHGATPE----SLVQESLAKVRA-RLESQD 376
Cdd:PRK12474 284 YP-----GKPSWGAPPgceivylaqpdeDLAQALQDLADAVDAPAEPAARTPLALPAlpkgALNSLGVAQLIAhRTPDQA 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 377 LGKElkfmadirEAVPADMqtFWDMTIAAywgwscwdARQGQFHSAQGaGGLGFAFPGAIGAAVGLetqgrPGR-VLAVS 455
Cdd:PRK12474 359 IYAD--------EALTSGL--FFDMSYDR--------ARPHTHLPLTG-GSIGQGLPLAAGAAVAA-----PDRkVVCPQ 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 456 GDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYM--VGAFGKATATE----LARP--DFVRLAESFGIPATRVAP 527
Cdd:PRK12474 415 GDGGAAYTMQALWTMARENLDVTVVIFANRSYAILNGELqrVGAQGAGRNALsmldLHNPelNWMKIAEGLGVEASRATT 494
|
570 580
....*....|....*....|
gi 1718153936 528 -EDVGDALKAGFAGDGPNVV 546
Cdd:PRK12474 495 aEEFSAQYAAAMAQRGPRLI 514
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
426-539 |
1.34e-13 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 69.46 E-value: 1.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 426 GGLGFAFPGAIGAAVGleTQGRPgrVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFG-KATAT 504
Cdd:cd02013 53 GNCGYALPAIIGAKAA--APDRP--VVAIAGDGAWGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQVDFYNnRFVGT 128
|
90 100 110
....*....|....*....|....*....|....*.
gi 1718153936 505 ELARPDFVRLAESFGIPATRV-APEDVGDALKAGFA 539
Cdd:cd02013 129 ELESESFAKIAEACGAKGITVdKPEDVGPALQKAIA 164
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
20-178 |
2.43e-13 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 67.76 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 20 DLVVETLEALGAKTVFGIPGQHALGLFDAMGRGN-LHFVSSRIENNSAFAADGYSRATGeVGVLFLSTGPGALTSLAGLQ 98
Cdd:cd06586 1 AAFAEVLTAWGVRHVFGYPGDEISSLLDALREGDkRIIDTVIHELGAAGAAAGYARAGG-PPVVIVTSGTGLLNAINGLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 99 EAYATGVPMVVVASQIPLEGLGarrkGMLHQLDDQKASAANVTKSQRLIQHASGIPSAIQDAWTEAISSpQGPVWLEIPQ 178
Cdd:cd06586 80 DAAAEHLPVVFLIGARGISAQA----KQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTAYAS-QGPVVVRLPR 154
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
412-562 |
3.91e-12 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 65.40 E-value: 3.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 412 WDARQ-GQFHSAQGAGGLGFAFPGAIGAAVGLetqgrPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGI 489
Cdd:cd02003 33 WRARTpGGYHLEYGYSCMGYEIAAGLGAKLAK-----PDReVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFGC 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 490 LREYMVGAFGKATATE--------------LARPDFVRLAESFGIPATRVAP-EDVGDALKAGFAGDGPNVVVVETLLKm 554
Cdd:cd02003 108 INNLQESTGSGSFGTEfrdrdqesgqldgaLLPVDFAANARSLGARVEKVKTiEELKAALAKAKASDRTTVIVIKTDPK- 186
|
....*...
gi 1718153936 555 fGPTHLGD 562
Cdd:cd02003 187 -SMTPGYG 193
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
425-553 |
2.44e-10 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 60.37 E-value: 2.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 425 AGGLGFAFPGAIGAAvgletQGRPGR-VLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILRE--------YMV 495
Cdd:cd02006 56 AGPLGWTVPAALGVA-----AADPDRqVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQaqrafdmdYQV 130
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1718153936 496 G-AFGKATATELA--RPDFVRLAESFGIPATRV-APEDVGDALKAG--FAGDGPNVVVVETLLK 553
Cdd:cd02006 131 NlAFENINSSELGgyGVDHVKVAEGLGCKAIRVtKPEELAAAFEQAkkLMAEHRVPVVVEAILE 194
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
435-550 |
1.15e-08 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 54.91 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 435 AIGAAVGletqgRPGRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILREYMVGAFGKATATELARP---DF 511
Cdd:cd02009 60 ALGIALA-----TDKPTVLLTGDLSFLHDLNGLLLGKQEPLNLTIVVINNNGGGIFSLLPQASFEDEFERLFGTPqglDF 134
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1718153936 512 VRLAESFGIPATRVA-PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:cd02009 135 EHLAKAYGLEYRRVSsLDELEQALESALAQDGPHVIEVKT 174
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
426-519 |
3.03e-07 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 50.61 E-value: 3.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 426 GGLGFAFPGAIGAAVGletqGRPGRVLAVSGDGSSMYSIAELATAKQHNVPVTWLIVDDGGYGILReYMVGafGKATATE 505
Cdd:cd02005 50 GSIGYSVPAALGAALA----APDRRVILLVGDGSFQMTVQELSTMIRYGLNPIIFLINNDGYTIER-AIHG--PEASYND 122
|
90
....*....|....
gi 1718153936 506 LARPDFVRLAESFG 519
Cdd:cd02005 123 IANWNYTKLPEVFG 136
|
|
| TPP_ComE |
cd03372 |
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins ... |
426-550 |
7.22e-05 |
|
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins similar to Methanococcus jannaschii sulfopyruvate decarboxylase beta subunit (ComE). M. jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits, which catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. ComDE requires TPP and divalent metal cation cofactors.
Pssm-ID: 239469 [Multi-domain] Cd Length: 179 Bit Score: 43.82 E-value: 7.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 426 GGLGFAFPGAIGAAVGLetqgrPGRVLAVSGDGSSMYSIAELATAKQHNVP-VTWLIVDDGGYGILreymvgafGKATAT 504
Cdd:cd03372 42 GSMGLASSIGLGLALAQ-----PRKVIVIDGDGSLLMNLGALATIAAEKPKnLIIVVLDNGAYGST--------GNQPTH 108
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1718153936 505 ELARPDFVRLAESFGIPATRV--APEDVGDALKAgfAGDGPNVVVVET 550
Cdd:cd03372 109 AGKKTDLEAVAKACGLDNVATvaSEEAFEKAVEQ--ALDGPSFIHVKI 154
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
434-548 |
1.58e-03 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 39.57 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 434 GAIGAAVGLETQGRPGRVLAVSGDGSSMYS-IAELATAKQHNVPVTWLIVDDGGYGilreyMVG-----AFGKATATELA 507
Cdd:cd02008 55 ASIGVAIGMAKASEDKKVVAVIGDSTFFHSgILGLINAVYNKANITVVILDNRTTA-----MTGgqphpGTGKTLTEPTT 129
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1718153936 508 RPDFVRLAESFGIPATR-VAPEDVG---DALKAGFAGDGPNVVVV 548
Cdd:cd02008 130 VIDIEALVRAIGVKRVVvVDPYDLKairEELKEALAVPGVSVIIA 174
|
|
| PRK06163 |
PRK06163 |
hypothetical protein; Provisional |
426-550 |
6.33e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235721 [Multi-domain] Cd Length: 202 Bit Score: 38.27 E-value: 6.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1718153936 426 GGLGFAFPGAIGAAVGLETQgrpgRVLAVSGDGSSMYSIAELAT-AKQHNVPVTWLIVDDGGYGIlreymVGAFGKATAT 504
Cdd:PRK06163 57 GSMGLAFPIALGVALAQPKR----RVIALEGDGSLLMQLGALGTiAALAPKNLTIIVMDNGVYQI-----TGGQPTLTSQ 127
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1718153936 505 ELarpDFVRLAESFGIPATRVA--PEDVGDALKAGFAGDGPNVVVVET 550
Cdd:PRK06163 128 TV---DVVAIARGAGLENSHWAadEAHFEALVDQALSGPGPSFIAVRI 172
|
|
| |
