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inositol monophosphatase family protein [Rhizobium rhizogenes]
FIG domain-containing protein( domain architecture ID 299)
FIG (FBPase/IMPase/glpX-like) domain-containing protein belongs to a superfamily of metal-dependent phosphatases with various substrates; such as fructose-1,6-bisphosphatase (both the major and the glpX-encoded variant), inositol-monophosphatases and inositol polyphosphatases
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
FIG super family | cl00289 | FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with ... |
15-227 | 3.33e-81 | ||||
FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in gluconeogenesis. Inositol-monophosphatases and inositol polyphosphatases play vital roles in eukaryotic signalling, as they participate in metabolizing the messenger molecule Inositol-1,4,5-triphosphate. Many of these enzymes are inhibited by Li+. The actual alignment was detected with superfamily member cd01643: Pssm-ID: 469707 [Multi-domain] Cd Length: 242 Bit Score: 243.78 E-value: 3.33e-81
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Name | Accession | Description | Interval | E-value | ||||
Bacterial_IMPase_like_2 | cd01643 | Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These ... |
15-227 | 3.33e-81 | ||||
Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates. Pssm-ID: 238821 [Multi-domain] Cd Length: 242 Bit Score: 243.78 E-value: 3.33e-81
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SuhB | COG0483 | Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family ... |
12-214 | 3.68e-66 | ||||
Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family [Carbohydrate transport and metabolism]; Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family is part of the Pathway/BioSystem: Gluconeogenesis Pssm-ID: 440251 [Multi-domain] Cd Length: 255 Bit Score: 205.85 E-value: 3.68e-66
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Inositol_P | pfam00459 | Inositol monophosphatase family; |
12-214 | 3.60e-45 | ||||
Inositol monophosphatase family; Pssm-ID: 459820 [Multi-domain] Cd Length: 271 Bit Score: 152.50 E-value: 3.60e-45
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his_9_HisN | TIGR02067 | histidinol-phosphatase, inositol monophosphatase family; This subfamily belongs to the ... |
15-229 | 1.72e-32 | ||||
histidinol-phosphatase, inositol monophosphatase family; This subfamily belongs to the inositol monophosphatase family (pfam00459). The members of this family consist of no more than one per species and are found only in species in which histidine is synthesized de novo but no histidinol phosphatase can be found in either of the two described families (TIGR01261, TIGR01856). In at least one species, the member of this family is found near known histidine biosynthesis genes. The role as histidinol-phosphatase wsa first proven in Corynebacterium glutamicum. [Amino acid biosynthesis, Histidine family] Pssm-ID: 273949 [Multi-domain] Cd Length: 251 Bit Score: 118.95 E-value: 1.72e-32
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PLN02553 | PLN02553 | inositol-phosphate phosphatase |
16-214 | 2.58e-32 | ||||
inositol-phosphate phosphatase Pssm-ID: 178168 [Multi-domain] Cd Length: 270 Bit Score: 119.02 E-value: 2.58e-32
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Name | Accession | Description | Interval | E-value | |||||
Bacterial_IMPase_like_2 | cd01643 | Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These ... |
15-227 | 3.33e-81 | |||||
Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates. Pssm-ID: 238821 [Multi-domain] Cd Length: 242 Bit Score: 243.78 E-value: 3.33e-81
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SuhB | COG0483 | Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family ... |
12-214 | 3.68e-66 | |||||
Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family [Carbohydrate transport and metabolism]; Archaeal fructose-1,6-bisphosphatase or related enzyme, inositol monophosphatase family is part of the Pathway/BioSystem: Gluconeogenesis Pssm-ID: 440251 [Multi-domain] Cd Length: 255 Bit Score: 205.85 E-value: 3.68e-66
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IMPase_like | cd01637 | Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent ... |
16-214 | 3.51e-53 | |||||
Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others. Pssm-ID: 238815 [Multi-domain] Cd Length: 238 Bit Score: 172.11 E-value: 3.51e-53
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IMPase | cd01639 | IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, ... |
17-214 | 8.28e-51 | |||||
IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria. Pssm-ID: 238817 [Multi-domain] Cd Length: 244 Bit Score: 166.17 E-value: 8.28e-51
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Inositol_P | pfam00459 | Inositol monophosphatase family; |
12-214 | 3.60e-45 | |||||
Inositol monophosphatase family; Pssm-ID: 459820 [Multi-domain] Cd Length: 271 Bit Score: 152.50 E-value: 3.60e-45
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CysQ | cd01638 | CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of ... |
16-210 | 1.90e-42 | |||||
CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in cysteine biosynthesis (a principal route of sulfur assimilation). Pssm-ID: 238816 [Multi-domain] Cd Length: 242 Bit Score: 144.68 E-value: 1.90e-42
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Bacterial_IMPase_like_1 | cd01641 | Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol ... |
15-214 | 1.16e-40 | |||||
Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate, or similar substrates. Pssm-ID: 238819 [Multi-domain] Cd Length: 248 Bit Score: 140.47 E-value: 1.16e-40
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CysQ | COG1218 | 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase [Inorganic ion transport and ... |
16-210 | 2.80e-34 | |||||
3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase [Inorganic ion transport and metabolism]; Pssm-ID: 440831 [Multi-domain] Cd Length: 260 Bit Score: 124.12 E-value: 2.80e-34
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his_9_HisN | TIGR02067 | histidinol-phosphatase, inositol monophosphatase family; This subfamily belongs to the ... |
15-229 | 1.72e-32 | |||||
histidinol-phosphatase, inositol monophosphatase family; This subfamily belongs to the inositol monophosphatase family (pfam00459). The members of this family consist of no more than one per species and are found only in species in which histidine is synthesized de novo but no histidinol phosphatase can be found in either of the two described families (TIGR01261, TIGR01856). In at least one species, the member of this family is found near known histidine biosynthesis genes. The role as histidinol-phosphatase wsa first proven in Corynebacterium glutamicum. [Amino acid biosynthesis, Histidine family] Pssm-ID: 273949 [Multi-domain] Cd Length: 251 Bit Score: 118.95 E-value: 1.72e-32
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PLN02553 | PLN02553 | inositol-phosphate phosphatase |
16-214 | 2.58e-32 | |||||
inositol-phosphate phosphatase Pssm-ID: 178168 [Multi-domain] Cd Length: 270 Bit Score: 119.02 E-value: 2.58e-32
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PRK10757 | PRK10757 | inositol-1-monophosphatase; |
17-209 | 6.20e-30 | |||||
inositol-1-monophosphatase; Pssm-ID: 236753 [Multi-domain] Cd Length: 267 Bit Score: 112.98 E-value: 6.20e-30
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PAP_phosphatase | cd01517 | PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase ... |
16-137 | 2.25e-28 | |||||
PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine biosynthesis and provides increased salt tolerance when over-expressed. Bacterial members of this domain family may differ in their substrate specificity and dephosphorylate different targets, as the substrate binding site does not appear to be conserved in that sub-set. Pssm-ID: 238775 [Multi-domain] Cd Length: 274 Bit Score: 108.94 E-value: 2.25e-28
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bisphos_cysQ | TIGR01331 | 3'(2'),5'-bisphosphate nucleotidase, bacterial; Sulfate is incorporated into ... |
17-235 | 5.87e-28 | |||||
3'(2'),5'-bisphosphate nucleotidase, bacterial; Sulfate is incorporated into 3-phosphoadenylylsulfate, PAPS, for utilization in pathways such as methionine biosynthesis. Transfer of sulfate from PAPS to an acceptor leaves adenosine 3'-5'-bisphosphate, APS. This model describes a form found in bacteria of the enzyme 3'(2'),5'-bisphosphate nucleotidase, which removes the 3'-phosphate from APS to regenerate AMP and help drive the cycle. [Central intermediary metabolism, Sulfur metabolism] Pssm-ID: 130398 [Multi-domain] Cd Length: 249 Bit Score: 107.15 E-value: 5.87e-28
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FIG | cd01636 | FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with ... |
15-219 | 4.28e-26 | |||||
FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in gluconeogenesis. Inositol-monophosphatases and inositol polyphosphatases play vital roles in eukaryotic signalling, as they participate in metabolizing the messenger molecule Inositol-1,4,5-triphosphate. Many of these enzymes are inhibited by Li+. Pssm-ID: 238814 [Multi-domain] Cd Length: 184 Bit Score: 100.54 E-value: 4.28e-26
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PLN02911 | PLN02911 | inositol-phosphate phosphatase |
15-225 | 9.13e-22 | |||||
inositol-phosphate phosphatase Pssm-ID: 178499 [Multi-domain] Cd Length: 296 Bit Score: 91.70 E-value: 9.13e-22
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PLN02737 | PLN02737 | inositol monophosphatase family protein |
16-218 | 1.51e-20 | |||||
inositol monophosphatase family protein Pssm-ID: 215392 [Multi-domain] Cd Length: 363 Bit Score: 89.47 E-value: 1.51e-20
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PRK12676 | PRK12676 | bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase; |
74-200 | 8.35e-13 | |||||
bifunctional fructose-bisphosphatase/inositol-phosphate phosphatase; Pssm-ID: 183673 [Multi-domain] Cd Length: 263 Bit Score: 66.47 E-value: 8.35e-13
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bisphos_HAL2 | TIGR01330 | 3'(2'),5'-bisphosphate nucleotidase, HAL2 family; Sulfate is incorporated into ... |
13-128 | 1.42e-11 | |||||
3'(2'),5'-bisphosphate nucleotidase, HAL2 family; Sulfate is incorporated into 3-phosphoadenylylsulfate, PAPS, for utilization in pathways such as methionine biosynthesis. Transfer of sulfate from PAPS to an acceptor leaves adenosine 3'-5'-bisphosphate, APS. This model describes a form found in plants of the enzyme 3'(2'),5'-bisphosphate nucleotidase, which removes the 3'-phosphate from APS to regenerate AMP and help drive the cycle. Sensitivity of this essential enzyme to sodium and other metal ions results is responsible for characterization of this enzyme as a salt tolerance protein. Some members of this family are active also as inositol 1-monophosphatase. Pssm-ID: 273558 [Multi-domain] Cd Length: 353 Bit Score: 63.35 E-value: 1.42e-11
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IPPase | cd01640 | IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of ... |
16-219 | 5.73e-11 | |||||
IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may also exhibit 3'-phosphoadenosine 5'-phosphate phosphatase activity, and they all appear to be inhibited by lithium. IPPase is one of the proposed targets of Li+ therapy in manic-depressive illness. Pssm-ID: 238818 [Multi-domain] Cd Length: 293 Bit Score: 61.18 E-value: 5.73e-11
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PRK10931 | PRK10931 | adenosine-3'(2'),5'-bisphosphate nucleotidase; Provisional |
20-133 | 2.14e-10 | |||||
adenosine-3'(2'),5'-bisphosphate nucleotidase; Provisional Pssm-ID: 182848 [Multi-domain] Cd Length: 246 Bit Score: 59.32 E-value: 2.14e-10
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Arch_FBPase_2 | cd01642 | Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. ... |
48-211 | 3.32e-10 | |||||
Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. These are Mg++ dependent phosphatases. Members in this family may have fructose-1,6-bisphosphatase and/or inositol-monophosphatase activity. Fructose-1,6-bisphosphatase catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. Pssm-ID: 238820 [Multi-domain] Cd Length: 244 Bit Score: 58.61 E-value: 3.32e-10
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Arch_FBPase_1 | cd01515 | Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family ... |
53-200 | 2.31e-08 | |||||
Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family (FBPase class IV). These are Mg++ dependent phosphatases. Members in this family may have both fructose-1,6-bisphosphatase and inositol-monophosphatase activity. In hyperthermophilic archaea, inositol monophosphatase is thought to play a role in the biosynthesis of di-myo-inositol-1,1'-phosphate, an osmolyte unique to hyperthermophiles. Pssm-ID: 238773 [Multi-domain] Cd Length: 257 Bit Score: 53.54 E-value: 2.31e-08
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Blast search parameters | ||||
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