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Conserved domains on  [gi|1872308608|ref|WP_180177345|]
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phosphopyruvate hydratase [Acinetobacter sp. YH12039]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 847.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNsilTMPVPMMNILNGGSHAD 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAK---TLPVPMMNIINGGAHAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDI 240
Cdd:COG0148   158 NNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 241 MLALDCASSEFYKDGQYILAGEGnKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV 320
Cdd:COG0148   238 ALALDVAASEFYKDGKYHLKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFV 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 321 TNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:COG0148   317 TNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSE 396

                         410       420       430
                  ....*....|....*....|....*....|
gi 1872308608 401 RVAKYNQLLRIEEL--TQAAYRGKAEFKGL 428
Cdd:COG0148   397 RVAKYNQLLRIEEElgDAARYAGRSAFKRL 426
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 847.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNsilTMPVPMMNILNGGSHAD 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAK---TLPVPMMNIINGGAHAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDI 240
Cdd:COG0148   158 NNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 241 MLALDCASSEFYKDGQYILAGEGnKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV 320
Cdd:COG0148   238 ALALDVAASEFYKDGKYHLKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFV 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 321 TNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:COG0148   317 TNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSE 396

                         410       420       430
                  ....*....|....*....|....*....|
gi 1872308608 401 RVAKYNQLLRIEEL--TQAAYRGKAEFKGL 428
Cdd:COG0148   397 RVAKYNQLLRIEEElgDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 1-429 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 823.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:PRK00077    1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNsilTMPVPMMNILNGGSHAD 160
Cdd:PRK00077   81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAK---VLPVPMMNIINGGAHAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDI 240
Cdd:PRK00077  158 NNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 241 MLALDCASSEFYKDGQYILAGEGnkaFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV 320
Cdd:PRK00077  238 ALALDCAASEFYKDGKYVLEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFV 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 321 TNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:PRK00077  315 TNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 394

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1872308608 401 RVAKYNQLLRIEEL--TQAAYRGKAEFKGLN 429
Cdd:PRK00077  395 RIAKYNQLLRIEEElgDAARYAGKKAFKNLK 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-413 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 721.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   6 DIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALLGKSVF 85
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  86 EQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNnsiLTMPVPMMNILNGGSHADNNVDI 165
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA---YVLPVPMFNVINGGAHAGNKLDF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 166 QEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQG--LNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDIMLA 243
Cdd:cd03313   158 QEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 244 LDCASSEFYKDGQYILAGEGNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVTNP 323
Cdd:cd03313   238 LDVAASEFYDEGKYVYDSDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 324 KILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVA 403
Cdd:cd03313   318 ERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTA 397

                         410
                  ....*....|
gi 1872308608 404 KYNQLLRIEE 413
Cdd:cd03313   398 KYNQLLRIEE 407
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-428 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 692.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   4 IVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALLGKS 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  84 VFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNSiltMPVPMMNILNGGSHADNNV 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYV---LPVPMMNIINGGAHADNNL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 164 DIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDIMLA 243
Cdd:TIGR01060 158 DFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 244 LDCASSEFY--KDGQYILAGEgNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVT 321
Cdd:TIGR01060 238 LDCAASEFYdeEDGKYVYKGE-NKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 322 NPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDR 401
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 1872308608 402 VAKYNQLLRIEEL--TQAAYRGKAEFKGL 428
Cdd:TIGR01060 397 IAKYNQLLRIEEElgDSARYAGKNSFYRF 425
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
143-426 9.10e-158

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 447.31  E-value: 9.10e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 143 LTMPVPMMNILNGGSHADNNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQG--LNTAVGDEGGFAPNLRSNEE 220
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 221 AITVILEAIEKTGYKAgsDIMLALDCASSEFY--KDGQYILAGEGN-----KAFTSNQFADYLAGFAKQYPIISIEDGLD 293
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGEksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 294 ESDWEGWSYLTSILGDKIQLVGDDLFVTNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGE 373
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1872308608 374 TEDSTIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEL--TQAAYRGKAEFK 426
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEElgSEAKYAGRSFRK 294
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 847.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:COG0148     1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNsilTMPVPMMNILNGGSHAD 160
Cdd:COG0148    81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAK---TLPVPMMNIINGGAHAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDI 240
Cdd:COG0148   158 NNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 241 MLALDCASSEFYKDGQYILAGEGnKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV 320
Cdd:COG0148   238 ALALDVAASEFYKDGKYHLKGEG-KELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFV 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 321 TNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:COG0148   317 TNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSE 396

                         410       420       430
                  ....*....|....*....|....*....|
gi 1872308608 401 RVAKYNQLLRIEEL--TQAAYRGKAEFKGL 428
Cdd:COG0148   397 RVAKYNQLLRIEEElgDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 1-429 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 823.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:PRK00077    1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNsilTMPVPMMNILNGGSHAD 160
Cdd:PRK00077   81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAK---VLPVPMMNIINGGAHAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDI 240
Cdd:PRK00077  158 NNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 241 MLALDCASSEFYKDGQYILAGEGnkaFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV 320
Cdd:PRK00077  238 ALALDCAASEFYKDGKYVLEGEG---LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFV 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 321 TNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:PRK00077  315 TNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSE 394

                         410       420       430
                  ....*....|....*....|....*....|.
gi 1872308608 401 RVAKYNQLLRIEEL--TQAAYRGKAEFKGLN 429
Cdd:PRK00077  395 RIAKYNQLLRIEEElgDAARYAGKKAFKNLK 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-413 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 721.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   6 DIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALLGKSVF 85
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  86 EQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNnsiLTMPVPMMNILNGGSHADNNVDI 165
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA---YVLPVPMFNVINGGAHAGNKLDF 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 166 QEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQG--LNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDIMLA 243
Cdd:cd03313   158 QEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 244 LDCASSEFYKDGQYILAGEGNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVTNP 323
Cdd:cd03313   238 LDVAASEFYDEGKYVYDSDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 324 KILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVA 403
Cdd:cd03313   318 ERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTA 397

                         410
                  ....*....|
gi 1872308608 404 KYNQLLRIEE 413
Cdd:cd03313   398 KYNQLLRIEE 407
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-428 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 692.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   4 IVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALLGKS 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  84 VFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNSiltMPVPMMNILNGGSHADNNV 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYV---LPVPMMNIINGGAHADNNL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 164 DIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQGLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKAGSDIMLA 243
Cdd:TIGR01060 158 DFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 244 LDCASSEFY--KDGQYILAGEgNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFVT 321
Cdd:TIGR01060 238 LDCAASEFYdeEDGKYVYKGE-NKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 322 NPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDR 401
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 1872308608 402 VAKYNQLLRIEEL--TQAAYRGKAEFKGL 428
Cdd:TIGR01060 397 IAKYNQLLRIEEElgDSARYAGKNSFYRF 425
PTZ00081 PTZ00081
enolase; Provisional
 1-423 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 557.35  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVgRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALL 80
Cdd:PTZ00081    1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMI-ALDGTEN-----KEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNSI--LTMPVPMMNI 152
Cdd:PTZ00081   80 GKDVTDQKKLDKLMVeQLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPTdkFVLPVPCFNV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 153 LNGGSHADNNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQ-GLN-TAVGDEGGFAPNLRSNEEAITVILEAIE 230
Cdd:PTZ00081  160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 231 KTGYKAGSDImlALDCASSEFY--KDGQYIL-----AGEGNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYL 303
Cdd:PTZ00081  240 KAGYEGKVKI--CMDVAASEFYdkEKKVYDLdfknpNNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 304 TSILGDKIQLVGDDLFVTNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLA 383
Cdd:PTZ00081  318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 1872308608 384 VGTAAGQIKTGSLCRSDRVAKYNQLLRIEEL--TQAAYRGKA 423
Cdd:PTZ00081  398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEElgSNAVYAGEN 439
PLN00191 PLN00191
enolase
 1-423 0e+00

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 547.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVVgRACAPSGASTGSREALELRDGDKaRYLGKGVKTAVNNVNTVIRDALL 80
Cdd:PLN00191   25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIADLRNNSILTMPVPMMNILNGGSHAD 160
Cdd:PLN00191  103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKLVLPVPAFNVINGGSHAG 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQ--GLNTAVGDEGGFAPNLRSNEEAITVILEAIEKTGYKagS 238
Cdd:PLN00191  183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT--G 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 239 DIMLALDCASSEFY-KDGQYIL-----AGEGNKAFTSNQFADYLAGFAKQYPIISIEDGLDESDWEGWSYLTSilGDKIQ 312
Cdd:PLN00191  261 KIKIGMDVAASEFYtKDKKYDLdfkeeNNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTS--LEDVQ 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 313 LVGDDLFVTNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIK 392
Cdd:PLN00191  339 IVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQIK 418

                         410       420       430
                  ....*....|....*....|....*....|...
gi 1872308608 393 TGSLCRSDRVAKYNQLLRIEEL--TQAAYRGKA 423
Cdd:PLN00191  419 TGAPCRSERLAKYNQLLRIEEElgDEAVYAGEN 451
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
143-426 9.10e-158

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 447.31  E-value: 9.10e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 143 LTMPVPMMNILNGGSHADNNVDIQEFMIEPVGFTSFSEALRAGAEIFHSLKSVLKKQG--LNTAVGDEGGFAPNLRSNEE 220
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 221 AITVILEAIEKTGYKAgsDIMLALDCASSEFY--KDGQYILAGEGN-----KAFTSNQFADYLAGFAKQYPIISIEDGLD 293
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGEksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 294 ESDWEGWSYLTSILGDKIQLVGDDLFVTNPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGE 373
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1872308608 374 TEDSTIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEL--TQAAYRGKAEFK 426
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEElgSEAKYAGRSFRK 294
Enolase_N pfam03952
Enolase, N-terminal domain;
4-134 5.35e-77

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 234.96  E-value: 5.35e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   4 IVDIRAREILDSRGNPTIEADVILASGVVGRACAPSGASTGSREALELRDGDKARYLGKGVKTAVNNVNTVIRDALLGKS 83
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1872308608  84 VFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYI 134
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 217-391 2.47e-14

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 71.97  E-value: 2.47e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 217 SNEEAITVILEAIektgykaGSDIMLALDCASSEFYKDGQyilagegnkaftsnQFADYLAgfakQYPIISIEDGLDESD 296
Cdd:cd00308    79 GSIERVRAVREAF-------GPDARLAVDANGAWTPKEAI--------------RLIRALE----KYGLAWIEEPCAPDD 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 297 WEGWSYLTSILGdkIQLVGDDLFVTNPKILqRGINEKVGNSILIKYNQIGTLTETLDAIYLAKANGyTTVISHRSGETED 376
Cdd:cd00308   134 LEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFG-IRVMVHGTLESSI 209

                         170
                  ....*....|....*
gi 1872308608 377 STIADLAVGTAAGQI 391
Cdd:cd00308   210 GTAAALHLAAALPND 224
PRK08350 PRK08350
hypothetical protein; Provisional
 1-413 7.79e-13

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 69.06  E-value: 7.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608   1 MSQIVDIRAREILDSRGNPTIEADVILASGVvGRACAPSgastgsrealelrDGDKARYLGKGvKTAVNNVNTVIRDALL 80
Cdd:PRK08350    1 MTVIENIIGRVAVLRGGKYSVEVDVITDSGF-GRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  81 GKSVFEQKDIDNTMIALDGTENKEKLGANATLAVSLAAARAAADEKKIPLFQYIAdlrNNSILTMPVPMMNILNgGSHAD 160
Cdd:PRK08350   66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIG---GTFTTELPVPILEFAE-DENFE 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 161 NNVDIQEFMiepvgftsfsealragaEIFHSLKSVLKkqglntavgdeggfapnLRSNEEAITV--ILEAIEKTGYKAGS 238
Cdd:PRK08350  142 YYVLVRDLM-----------------EITDVVDAVNK-----------------ILENSKEVSLegLSKASEKAGDELGL 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 239 DIMLALdcassefykdgqyILAGEGNKAFTSNQFADYLAGFAKqyPIISIEdgldesdwegwSYLTSILGDK-IQLVGDD 317
Cdd:PRK08350  188 EVALGI-------------AQKREMETEKVLNLVEDNNIAYIK--PIGDEE-----------LFLELIAGTHgVFIDGEY 241

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 318 LFVTNpKILQRgineKVGNSILIKYNQIGTLTETLDAIYLAKANGYTTVISHRSGETEDSTIADLAVGTAAGQIktgsLC 397
Cdd:PRK08350  242 LFRTR-NILDR----RYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----LI 312

                         410
                  ....*....|....*.
gi 1872308608 398 RSDRVAKYNQLLRIEE 413
Cdd:PRK08350  313 HKDSVEKINELNRIAE 328
PTZ00378 PTZ00378
hypothetical protein; Provisional
 33-416 3.36e-06

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 49.10  E-value: 3.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608  33 GRACAPSGASTGSREALElrdgdkARYLGKgvktavnnvntvirdaLLGKSVFEQKDIDNTMIALDGTENKEKLGANATL 112
Cdd:PTZ00378   95 GEADATLDPAEYTTEALQ------NSYFPR----------------LLQLGARDQREFDSTLRAALSTSPLANVGSAVQW 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 113 AVSLAAARAAADEKKIPLFQYIADL--RNNSILTMPVPMMNI--LNGGSHADNNVDIQEFMIEPVgFTSFS------EAL 182
Cdd:PTZ00378  153 ALSIVASLAAARCRSVPLFQYLRALfgSLTSVETFSMPQLCItfFGPGNPSTARLALKSVLFSPV-MPSGTvlrermQKI 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 183 RAGAEIFhslksvlkKQGLNTAVGDEGGFAPNLRSN-EEAITVILEAIEKTGYKAGSDIMLAL---------------DC 246
Cdd:PTZ00378  232 FAAFHHF--------CQSHNSSVRSDGSLHWDGFANlTDAVKLATEALRAVQLTPGTDVCLGLrmaasttrvpatavaDG 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 247 ASSEFYKDGQYILAG--EGNKAFTSNQFADYLAGFAKQYP--IISIEDGLDESDWEGWSYLTSILGDKIQLVGDDLFV-T 321
Cdd:PTZ00378  304 GAWKEAKDDCEVLYSlfPGEPDVTGDQLSEYVREQLQAVPdiVVYVEDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArS 383

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1872308608 322 NPKILQRGINEKVGNSILIKYNQIGTLTETLDAIYLAKAN-GYTTVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSD 400
Cdd:PTZ00378  384 EYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEDeGRAVTVLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAH 463

                         410
                  ....*....|....*..
gi 1872308608 401 RVAKYNQLL-RIEELTQ 416
Cdd:PTZ00378  464 QCEVVSQLAsRQDELTH 480
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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