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Conserved domains on  [gi|1896817105|ref|WP_186822236|]
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MULTISPECIES: DUF3173 family protein [Streptococcus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3173 super family cl12907
Domain of unknown function (DUF3173); This family of proteins with unknown function appears to ...
 3-74 2.56e-17

Domain of unknown function (DUF3173); This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualization confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).


The actual alignment was detected with superfamily member pfam11372:

Pssm-ID: 402810  Cd Length: 58  Bit Score: 68.45  E-value: 2.56e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1896817105  3 QTINHTELMKLGFPEHTARDIIKQAKLIAVRQfeesralsnnvvelSKSPFDNSRLNLAPTYIVEELLGFKL 74
Cdd:pfam11372  1 KTVTKKDLIKLGFKPSTARDIIREAKALLVEK--------------GYTFYNNKRLGRVPVSAVEELLGIEL 58
 
Name Accession Description Interval E-value
DUF3173 pfam11372
Domain of unknown function (DUF3173); This family of proteins with unknown function appears to ...
 3-74 2.56e-17

Domain of unknown function (DUF3173); This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualization confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).


Pssm-ID: 402810  Cd Length: 58  Bit Score: 68.45  E-value: 2.56e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1896817105  3 QTINHTELMKLGFPEHTARDIIKQAKLIAVRQfeesralsnnvvelSKSPFDNSRLNLAPTYIVEELLGFKL 74
Cdd:pfam11372  1 KTVTKKDLIKLGFKPSTARDIIREAKALLVEK--------------GYTFYNNKRLGRVPVSAVEELLGIEL 58
 
Name Accession Description Interval E-value
DUF3173 pfam11372
Domain of unknown function (DUF3173); This family of proteins with unknown function appears to ...
 3-74 2.56e-17

Domain of unknown function (DUF3173); This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualization confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).


Pssm-ID: 402810  Cd Length: 58  Bit Score: 68.45  E-value: 2.56e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1896817105  3 QTINHTELMKLGFPEHTARDIIKQAKLIAVRQfeesralsnnvvelSKSPFDNSRLNLAPTYIVEELLGFKL 74
Cdd:pfam11372  1 KTVTKKDLIKLGFKPSTARDIIREAKALLVEK--------------GYTFYNNKRLGRVPVSAVEELLGIEL 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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