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Conserved domains on  [gi|1906103757|ref|WP_188879620|]
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histidine kinase [Halarchaeum grantii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DICT super family cl46778
Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain ...
 93-242 1.49e-27

Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain found associated with GGDEF, EAL, HD-GYP, STAS, and two component systems (histidine-kinase type). It assumes an alpha+beta fold with a 4-stranded beta-sheet and might have a role in light response (Natural history of sensor domains in bacterial signaling systems by Aravind L, LM Iyer, Anantharaman V, from 'Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.' Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter)


The actual alignment was detected with superfamily member COG4250:

Pssm-ID: 481118  Cd Length: 178  Bit Score: 103.85  E-value: 1.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757  93 EDAELPAVLAGLEDTRFDVrgypeteKDKLLLIAVSRAIEREAW-LAGEGRLRSAFQRLSRMNDEsgtRAVYETLAETDV 171
Cdd:COG4250     4 SGSILQELLDALPETRFTV-------YFKSSLVALSRAIEDRALrVDGKGLLIAGFQRESFYRQE---ADRYRRLADRSL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757 172 DVHVYGTPDWMPPVGFDVTAHAGYGDDF-RRGWFVVFRRPEgGGTALVAY--------ADTPRQWSGFWTSRDDVVDAVA 242
Cdd:COG4250    74 QVHVYAAPDTEFPDHDNVTVHALEPADElAQEWFLVIDGPD-YKAALLAEerspglpeMDQERRFYGFWTFDPELVDEAA 152
 
Name Accession Description Interval E-value
DICT COG4250
DICT sensory domain found in diguanylate cyclases and two-component systems [Signal ...
 93-242 1.49e-27

DICT sensory domain found in diguanylate cyclases and two-component systems [Signal transduction mechanisms];


Pssm-ID: 443392  Cd Length: 178  Bit Score: 103.85  E-value: 1.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757  93 EDAELPAVLAGLEDTRFDVrgypeteKDKLLLIAVSRAIEREAW-LAGEGRLRSAFQRLSRMNDEsgtRAVYETLAETDV 171
Cdd:COG4250     4 SGSILQELLDALPETRFTV-------YFKSSLVALSRAIEDRALrVDGKGLLIAGFQRESFYRQE---ADRYRRLADRSL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757 172 DVHVYGTPDWMPPVGFDVTAHAGYGDDF-RRGWFVVFRRPEgGGTALVAY--------ADTPRQWSGFWTSRDDVVDAVA 242
Cdd:COG4250    74 QVHVYAAPDTEFPDHDNVTVHALEPADElAQEWFLVIDGPD-YKAALLAEerspglpeMDQERRFYGFWTFDPELVDEAA 152
DICT pfam10069
Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain ...
 121-207 6.68e-06

Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain found associated with GGDEF, EAL, HD-GYP, STAS, and two component systems (histidine-kinase type). It assumes an alpha+beta fold with a 4-stranded beta-sheet and might have a role in light response (Natural history of sensor domains in bacterial signaling systems by Aravind L, LM Iyer, Anantharaman V, from 'Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.' Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter)


Pssm-ID: 431029  Cd Length: 126  Bit Score: 44.16  E-value: 6.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757 121 KLLLIAVSRAIEREAW-LAGEGRLRSAFQRLSRMNDEsgtRAVYETLAETDVDVHVYGTPD-------WMPPVGFDVTAH 192
Cdd:pfam10069  24 KATLTALSHALEDLLIeQQIPATVWAKFQRGKFYRQE---ADRYQQLAQKSRQIYVCAAPEsefaepdSSSDNVETVALD 100

                          90
                  ....*....|....*
gi 1906103757 193 AGYgDDFRRGWFVVF 207
Cdd:pfam10069 101 PNS-DPLRREWFLIV 114
 
Name Accession Description Interval E-value
DICT COG4250
DICT sensory domain found in diguanylate cyclases and two-component systems [Signal ...
 93-242 1.49e-27

DICT sensory domain found in diguanylate cyclases and two-component systems [Signal transduction mechanisms];


Pssm-ID: 443392  Cd Length: 178  Bit Score: 103.85  E-value: 1.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757  93 EDAELPAVLAGLEDTRFDVrgypeteKDKLLLIAVSRAIEREAW-LAGEGRLRSAFQRLSRMNDEsgtRAVYETLAETDV 171
Cdd:COG4250     4 SGSILQELLDALPETRFTV-------YFKSSLVALSRAIEDRALrVDGKGLLIAGFQRESFYRQE---ADRYRRLADRSL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757 172 DVHVYGTPDWMPPVGFDVTAHAGYGDDF-RRGWFVVFRRPEgGGTALVAY--------ADTPRQWSGFWTSRDDVVDAVA 242
Cdd:COG4250    74 QVHVYAAPDTEFPDHDNVTVHALEPADElAQEWFLVIDGPD-YKAALLAEerspglpeMDQERRFYGFWTFDPELVDEAA 152
DICT pfam10069
Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain ...
 121-207 6.68e-06

Sensory domain in DIguanylate Cyclases and Two-component system; DICT is a sensory domain found associated with GGDEF, EAL, HD-GYP, STAS, and two component systems (histidine-kinase type). It assumes an alpha+beta fold with a 4-stranded beta-sheet and might have a role in light response (Natural history of sensor domains in bacterial signaling systems by Aravind L, LM Iyer, Anantharaman V, from 'Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.' Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter)


Pssm-ID: 431029  Cd Length: 126  Bit Score: 44.16  E-value: 6.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906103757 121 KLLLIAVSRAIEREAW-LAGEGRLRSAFQRLSRMNDEsgtRAVYETLAETDVDVHVYGTPD-------WMPPVGFDVTAH 192
Cdd:pfam10069  24 KATLTALSHALEDLLIeQQIPATVWAKFQRGKFYRQE---ADRYQQLAQKSRQIYVCAAPEsefaepdSSSDNVETVALD 100

                          90
                  ....*....|....*
gi 1906103757 193 AGYgDDFRRGWFVVF 207
Cdd:pfam10069 101 PNS-DPLRREWFLIV 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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