|
Name |
Accession |
Description |
Interval |
E-value |
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-802 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1147.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 1 MS---STEKFQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYH 77
Cdd:COG0188 1 MSdppPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 78 PHGDSSVYEAMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTV 157
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 158 LPARFPNLLVNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRG 237
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 238 KIIVRAQAVVEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQY 317
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 318 LFKTTDLQVAYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRS 397
Cdd:COG0188 321 LYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 398 SNDKKDAKLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRF 477
Cdd:COG0188 401 SKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 478 TEPRRSkiEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASNG-----QDFAMKDSDYLLYEANLNTQHHLL 552
Cdd:COG0188 481 GDERRT--EIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRggkgvSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 553 LFTNRGNYIYQPVHELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQpNTYVFTATKDGQIKRSPLADYAVTRySK 632
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDE-DKYLLFATKKGTVKKTPLSDFSNIR-KN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 633 PIKTMNVKAGDAMIYASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQPDvtQYVVIV 712
Cdd:COG0188 637 GIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEE--DDLLTV 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 713 TQRGAVKKMNVAEVEVAGRAKRGLKVLTELKANPHrIVAVVQATDGEQVVIETEKGVQEVIDVQALSRADRHSNGSFKVD 792
Cdd:COG0188 715 TENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGK-LVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIR 793
|
810
....*....|
gi 1966496496 793 IATDGAISHV 802
Cdd:COG0188 794 LDEGDKVVSV 803
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-748 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1030.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 1 MSSTEKFQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHG 80
Cdd:PRK05561 4 MSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 81 DSSVYEAMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPA 160
Cdd:PRK05561 84 DSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 161 RFPNLLVNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGG-IIQGVDGIKKAYETGRGKI 239
Cdd:PRK05561 164 RFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGSI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 240 IVRAQAVVEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTG-LRVVIELKKD-VPGQGILQY 317
Cdd:PRK05561 244 RVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNrVDPEALMNH 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 318 LFKTTDLQVAYNFNMIAIH-NRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIR 396
Cdd:PRK05561 324 LFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIR 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 397 SSndkKDAKLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKR 476
Cdd:PRK05561 404 ES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKK 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 477 FTEPRRSKIEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASngqDFAMKDSDYLLYEANLNTQHHLLLFTN 556
Cdd:PRK05561 481 FGDPRRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS---GLSFKEGDSLLFAFEARTTDKLLLFTS 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 557 RGNYIYQPVHELPDIRwKDlGQHISSIVPTGEDESIIAVYGFEtfeqPNTYVFTATKDGQIKRSPLAD-YAVTRYSKPIk 635
Cdd:PRK05561 558 TGRVYSLPVHELPSAR-GD-GEPLTGLVDLAPGEEIVHVLAFD----PDQKLLLASSAGYGFVVTLEDlVARTRAGKAV- 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 636 tMNVKAGDAMIYASFVTDGVELMLTTDTAYAIRFPMEELPVTGvKTGGVKGITLK-DGEALVGVNVLQPDVTqyVVIVTQ 714
Cdd:PRK05561 631 -INLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELG-KGKGVKLINLPkDDDGLVDLRVLNPEDG--LVLLTA 706
|
730 740 750
....*....|....*....|....*....|....*.
gi 1966496496 715 RGAVKKMNVAEVE--VAGRAKRGLKVLTELKANPHR 748
Cdd:PRK05561 707 GKRKLKLKPSELEkyRGKRARRGRLLPRGLKRVPRF 742
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
7-747 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 1006.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 7 FQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYE 86
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 87 AMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLL 166
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 167 VNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAV 246
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 247 VEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQV 326
Cdd:TIGR01061 241 IEVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 327 AYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKL 406
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 407 NLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPRRSKIE 486
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 487 QEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASNGQDFAMKDSDYLLYEANLNTQHHLLLFTNRGNYIYQPVH 566
Cdd:TIGR01061 481 DFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGSKDDDILFAQTIANTTDQILIFTSLGNIINIPVH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 567 ELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQPNTYVFTATKDGQIKRSPLADYAVTRYSKPIKTMNVKAGDAMI 646
Cdd:TIGR01061 561 KLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDVDQPILVLASKLGMVKRIELTELNIKRNSKATLCIKLKDKDHLI 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 647 YASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQpdVTQYVVIVTQRGAVKKMNVAEV 726
Cdd:TIGR01061 641 SAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFE--ANESLVLLTQRGSVKRLSISEL 718
|
730 740
....*....|....*....|.
gi 1966496496 727 EVAGRAKRGLKVLtELKANPH 747
Cdd:TIGR01061 719 VVTSRAATGKKLL-PLKKKPH 738
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
29-473 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 650.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 29 QDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLIEMHGNN 108
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 109 GSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGSTGISAGYATDIPPHALDE 188
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 189 VLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPIKgGKEQIVITELPYDVNK 268
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE-GRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 269 ANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFNMIAI-HNRRPTMMTLPL 347
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNLKE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 348 LLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEKFDFTEVQAEAIVSLQL 427
Cdd:cd00187 320 ILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDMRL 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1966496496 428 YRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDI 473
Cdd:cd00187 400 RRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-462 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 595.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 10 LPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 90 RMSQDWKARHMLIEMHGNNGSV-DGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVN 168
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 169 GSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQgvdgikkayetGRGKIIVRAQAVVE 248
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 249 pikgGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDES-DRTGLRVVIELKKDVPGQGILQYLFKTTDLQVA 327
Cdd:smart00434 230 ----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 328 YNFNMIAIH-NRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAK-DRSHIVDGLIKALSILDEVIATIRSSNDK-KDA 404
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLaKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1966496496 405 KLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKL 462
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWL 443
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
31-470 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 589.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 31 RALPDARDGLKPVQRRILYAMFtEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLIEMHGNNGS 110
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 111 V-DGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGSTGISAGYATDIPPHALDEV 189
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 190 LDAVLMRLDKPNVTVdeLMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPikggKEQIVITELPYDVNKA 269
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 270 NLVKKIDEQRVDKRLEGIAEIRDESDRtGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFNMIAIHNRRPTMMTLPLLL 349
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 350 DAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEKfdFTEVQAEAIVSLQLYR 429
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1966496496 430 LTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQEL 470
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
23-121 |
4.40e-36 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 147.56 E-value: 4.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 23 YSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLI 102
Cdd:NF038098 18 YAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLV 97
|
90
....*....|....*....
gi 1966496496 103 EMHGNNGSVDGDPPAAMRY 121
Cdd:NF038098 98 DGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-802 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1147.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 1 MS---STEKFQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYH 77
Cdd:COG0188 1 MSdppPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 78 PHGDSSVYEAMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTV 157
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 158 LPARFPNLLVNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRG 237
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 238 KIIVRAQAVVEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQY 317
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDGMRIVIELKRDANPEVVLNQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 318 LFKTTDLQVAYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRS 397
Cdd:COG0188 321 LYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 398 SNDKKDAKLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRF 477
Cdd:COG0188 401 SKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 478 TEPRRSkiEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASNG-----QDFAMKDSDYLLYEANLNTQHHLL 552
Cdd:COG0188 481 GDERRT--EIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRggkgvSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 553 LFTNRGNYIYQPVHELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQpNTYVFTATKDGQIKRSPLADYAVTRySK 632
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDE-DKYLLFATKKGTVKKTPLSDFSNIR-KN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 633 PIKTMNVKAGDAMIYASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQPDvtQYVVIV 712
Cdd:COG0188 637 GIIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEE--DDLLTV 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 713 TQRGAVKKMNVAEVEVAGRAKRGLKVLTELKANPHrIVAVVQATDGEQVVIETEKGVQEVIDVQALSRADRHSNGSFKVD 792
Cdd:COG0188 715 TENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGK-LVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIR 793
|
810
....*....|
gi 1966496496 793 IATDGAISHV 802
Cdd:COG0188 794 LDEGDKVVSV 803
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-748 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1030.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 1 MSSTEKFQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHG 80
Cdd:PRK05561 4 MSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 81 DSSVYEAMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPA 160
Cdd:PRK05561 84 DSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 161 RFPNLLVNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGG-IIQGVDGIKKAYETGRGKI 239
Cdd:PRK05561 164 RFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGeIITGRDGIRKAYETGRGSI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 240 IVRAQAVVEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTG-LRVVIELKKD-VPGQGILQY 317
Cdd:PRK05561 244 RVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENpVRIVIEPKSNrVDPEALMNH 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 318 LFKTTDLQVAYNFNMIAIH-NRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIR 396
Cdd:PRK05561 324 LFATTDLESSYRVNMNAIGlDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIR 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 397 SSndkKDAKLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKR 476
Cdd:PRK05561 404 ES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKK 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 477 FTEPRRSKIEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASngqDFAMKDSDYLLYEANLNTQHHLLLFTN 556
Cdd:PRK05561 481 FGDPRRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS---GLSFKEGDSLLFAFEARTTDKLLLFTS 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 557 RGNYIYQPVHELPDIRwKDlGQHISSIVPTGEDESIIAVYGFEtfeqPNTYVFTATKDGQIKRSPLAD-YAVTRYSKPIk 635
Cdd:PRK05561 558 TGRVYSLPVHELPSAR-GD-GEPLTGLVDLAPGEEIVHVLAFD----PDQKLLLASSAGYGFVVTLEDlVARTRAGKAV- 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 636 tMNVKAGDAMIYASFVTDGVELMLTTDTAYAIRFPMEELPVTGvKTGGVKGITLK-DGEALVGVNVLQPDVTqyVVIVTQ 714
Cdd:PRK05561 631 -INLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELG-KGKGVKLINLPkDDDGLVDLRVLNPEDG--LVLLTA 706
|
730 740 750
....*....|....*....|....*....|....*.
gi 1966496496 715 RGAVKKMNVAEVE--VAGRAKRGLKVLTELKANPHR 748
Cdd:PRK05561 707 GKRKLKLKPSELEkyRGKRARRGRLLPRGLKRVPRF 742
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
7-747 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 1006.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 7 FQDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYE 86
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 87 AMVRMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLL 166
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 167 VNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAV 246
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 247 VEPIKGGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQV 326
Cdd:TIGR01061 241 IEVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNGIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 327 AYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKL 406
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 407 NLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPRRSKIE 486
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 487 QEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASNGQDFAMKDSDYLLYEANLNTQHHLLLFTNRGNYIYQPVH 566
Cdd:TIGR01061 481 DFINQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGSKDDDILFAQTIANTTDQILIFTSLGNIINIPVH 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 567 ELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQPNTYVFTATKDGQIKRSPLADYAVTRYSKPIKTMNVKAGDAMI 646
Cdd:TIGR01061 561 KLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDVDQPILVLASKLGMVKRIELTELNIKRNSKATLCIKLKDKDHLI 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 647 YASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQpdVTQYVVIVTQRGAVKKMNVAEV 726
Cdd:TIGR01061 641 SAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFE--ANESLVLLTQRGSVKRLSISEL 718
|
730 740
....*....|....*....|.
gi 1966496496 727 EVAGRAKRGLKVLtELKANPH 747
Cdd:TIGR01061 719 VVTSRAATGKKLL-PLKKKPH 738
|
|
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
12-781 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 907.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 12 LEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRM 91
Cdd:PRK05560 10 IEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVYDALVRM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 92 SQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGST 171
Cdd:PRK05560 90 AQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGSS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 172 GISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPIK 251
Cdd:PRK05560 170 GIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAKAEIEEIK 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 252 gGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFN 331
Cdd:PRK05560 250 -GREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDGMRIVIELKRDAVPEVVLNNLYKHTQLQTSFGIN 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 332 MIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEK 411
Cdd:PRK05560 329 MLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEAKEGLMER 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 412 FDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPRRSkieqEIEE 491
Cdd:PRK05560 409 FGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRT----EIIE 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 492 IKITLDV--LVPSEEVVVTVTKDGYIKRTSTRSHAASN----G-QDFAMKDSDYL--LYEAnlNTQHHLLLFTNRGNyIY 562
Cdd:PRK05560 485 GEGDIDDedLIPEEDVVVTLTHGGYIKRTPLDEYRAQRrggkGvSGAKTKEDDFVehLFVA--STHDTLLFFTNRGR-VY 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 563 Q-PVHELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQpNTYVFTATKDGQIKRSPLADYAVTRySKPIKTMNVKA 641
Cdd:PRK05560 562 RlKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDD-DKYLFFATKNGTVKKTSLSEFSNIR-SNGIIAINLDE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 642 GDAMIYASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQPDvTQYVVIVTQRGAVKKM 721
Cdd:PRK05560 640 GDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVRED-SQEILTVTENGYGKRT 718
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1966496496 722 NVAEVEVAGRAKRGLKVlteLKANPHR--IVAVVQATDGEQVVIETEKGV---QEVIDVQALSRA 781
Cdd:PRK05560 719 PVSEYRLQGRGGKGVIT---IKITEKNgkLVGALPVDDDDEIMLITDSGKlirTRVSEISITGRN 780
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
12-787 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 836.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 12 LEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRM 91
Cdd:TIGR01063 6 IEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDTLVRM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 92 SQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGST 171
Cdd:TIGR01063 86 AQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGSS 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 172 GISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPIK 251
Cdd:TIGR01063 166 GIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAEIEEDS 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 252 GGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFN 331
Cdd:TIGR01063 246 KGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREGIRIVIELKRDAVAEVVLNNLYKQTQLQVSFGIN 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 332 MIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEK 411
Cdd:TIGR01063 326 MLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKTRLVER 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 412 FDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPRRSKIEQEIEE 491
Cdd:TIGR01063 406 FSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYDESE 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 492 IKITLDvLVPSEEVVVTVTKDGYIKRTSTRSHAASNG-----QDFAMKDSDYLLYEANLNTQHHLLLFTNRGNYIYQPVH 566
Cdd:TIGR01063 486 DIDIED-LIARENVVVTLSHNGYVKRVPVSAYRLQKRggkgvSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYWLKVY 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 567 ELPDIRWKDLGQHISSIVPTGEDESIIAVYGFETFEQpNTYVFTATKDGQIKRSPLADYAVTRySKPIKTMNVKAGDAMI 646
Cdd:TIGR01063 565 QIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDD-GLYLFFATKNGVVKKTSLTEFSNIR-SNGIIAIKLDDGDELI 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 647 YASFVTDGVELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVLQPDvtQYVVIVTQRGAVKKMNVAEV 726
Cdd:TIGR01063 643 SVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEE--SYLLIVTENGYGKRTSIEEY 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1966496496 727 EVAGRAKRGLKVLTeLKANPHRIVAVVQATDGEQVVIETEKGVQEVIDVQALSRADRHSNG 787
Cdd:TIGR01063 721 RETSRGGKGVKSIK-ITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQG 780
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
10-651 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 707.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 10 LPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:PRK13979 16 IPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 90 RMSQDWKARHMLIEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNG 169
Cdd:PRK13979 96 ILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 170 STGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEP 249
Cdd:PRK13979 176 AFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTKIEK 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 250 IKGGKEQIVITELPYDVNKANLVKKIDEQRVDKR----LEGIAEIRDESDRTGLRVVIELKKDVP---GQGILQYLFKTT 322
Cdd:PRK13979 256 LENGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESDRNGIRAVIEFKKSADedvAEKVLKYLYKKT 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 323 DLQVAYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKK 402
Cdd:PRK13979 336 DLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSKSKK 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 403 DAKLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPRR 482
Cdd:PRK13979 416 DASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERR 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 483 SKIEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKRTSTRSHAASNG--QDFAMKDSDYLLYEANLNTQHHLLLFTNRGNy 560
Cdd:PRK13979 496 TSIIEDDEKAKIDVEELIVVEDVVITLSNEGFIKRIPLKSYNRSNSnvEDIEYREGDFNKFLIQSNTKDTLLIFTDKGN- 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 561 IYQ-PVHELPDIRWKDLGQHISSIVPTG--EDESIIAVYGFETFEQPNTYVFTaTKDGQIKRSPLaDYAVTRYSKpIKTM 637
Cdd:PRK13979 575 MYQiKGINIPEFKWKEKGERLDEIIKGIdlESEKIIEAYSIEDFTPQKDFIFI-TDSGGIKKTSL-DKFVTNYTK-LMAL 651
|
650
....*....|....
gi 1966496496 638 NVKAGDAMIYASFV 651
Cdd:PRK13979 652 KLKKGEKLIKVKLV 665
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
29-473 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 650.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 29 QDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLIEMHGNN 108
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 109 GSVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGSTGISAGYATDIPPHALDE 188
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 189 VLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPIKgGKEQIVITELPYDVNK 268
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDE-GRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 269 ANLVKKIDEQRVDKRLEGIAEIRDESDRTGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFNMIAI-HNRRPTMMTLPL 347
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFdPNGRPKKLNLKE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 348 LLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEKFDFTEVQAEAIVSLQL 427
Cdd:cd00187 320 ILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDMRL 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1966496496 428 YRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDI 473
Cdd:cd00187 400 RRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-462 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 595.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 10 LPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMV 89
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 90 RMSQDWKARHMLIEMHGNNGSV-DGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVN 168
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 169 GSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGGIIQgvdgikkayetGRGKIIVRAQAVVE 248
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 249 pikgGKEQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDES-DRTGLRVVIELKKDVPGQGILQYLFKTTDLQVA 327
Cdd:smart00434 230 ----DDNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 328 YNFNMIAIH-NRRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAK-DRSHIVDGLIKALSILDEVIATIRSSNDK-KDA 404
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDLaKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1966496496 405 KLNLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKL 462
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWL 443
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
31-470 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 589.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 31 RALPDARDGLKPVQRRILYAMFtEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLIEMHGNNGS 110
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMF-ELLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 111 V-DGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGSTGISAGYATDIPPHALDEV 189
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 190 LDAVLMRLDKPNVTVdeLMTVMKGPDFPTGGIIQGVDGIKKAYETGRGKIIVRAQAVVEPikggKEQIVITELPYDVNKA 269
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 270 NLVKKIDEQRVDKRLEGIAEIRDESDRtGLRVVIELKKDVPGQGILQYLFKTTDLQVAYNFNMIAIHNRRPTMMTLPLLL 349
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDR-GVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 350 DAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDKKDAKLNLQEKfdFTEVQAEAIVSLQLYR 429
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1966496496 430 LTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQEL 470
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
8-701 |
6.48e-155 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 469.77 E-value: 6.48e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 8 QDLPLEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEA 87
Cdd:TIGR01062 2 ENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 88 MVRMSQDWKARHMLIEMHGNNGSVDG-DPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVPNFDDQDMEPTVLPARFPNLL 166
Cdd:TIGR01062 82 MVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNIL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 167 VNGSTGISAGYATDIPPHALDEVLDAVLMRLDKPNVTVDELMTVMKGPDFPTGG-IIQGVDGIKKAYETGRGKIIVRAQA 245
Cdd:TIGR01062 162 LNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAeIIDKAEEIRKIYETGRGSFRMRARW 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 246 VVEPIkggkeQIVITELPYDVNKANLVKKIDEQRVDKRLEGIAEIRDESDRTG-LRVVIELKKD-VPGQGILQYLFKTTD 323
Cdd:TIGR01062 242 KKEDG-----QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENpIRVVIVPRSNrVDPDIVMEHLFATTD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 324 LQVAY--NFNMIAIHNrRPTMMTLPLLLDAYIAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKALSILDEVIATIRSSNDK 401
Cdd:TIGR01062 317 LEKSYrlNMNMIGLDN-VPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDEP 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 402 KDAklnLQEKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQSEAKLVRVIKQELLDIKKRFTEPR 481
Cdd:TIGR01062 396 KTI---LMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLAR 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 482 RSKIEQEIEEIKITLDVLVPSEEVVVTVTKDGYIKrtSTRSHaASNGQDFAMKDSDYLLYEANLNTQHHLLLFTNRGNYI 561
Cdd:TIGR01062 473 RSSLEEREEAKQVSEIDMIPKEPVTIILSKMGWVR--SAKGH-DIDLSTLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSY 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 562 YQPVHELPDIRWKDLGQHISSIVPTGEDESIIAVYgfetfeQPNTYVFTATKDGQIKRSPLADY-AVTRYSKPIktMNVK 640
Cdd:TIGR01062 550 ALDPDNLPSARGQGEPLTGKLLLPIGATITNILMY------SPNQLLLMASDAGYGFLCNFNDLiARNKAGKAL--INLP 621
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1966496496 641 AGDAMIYASFVTDGVELMLT-TDTAYAIRFPMEELPVTGvKTGGVKGITLKDGEALVGVNVL 701
Cdd:TIGR01062 622 ENASVIAPLPVNGDSDMIAAiTEAGRMLVFPIDDLPELS-KGKGNKLIRIPSANAKRGEDGL 682
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
12-483 |
6.93e-66 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 231.52 E-value: 6.93e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 12 LEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFtegNTHDKPFRKsaktVGNVIGN---YHPHGDSSVYEAM 88
Cdd:PRK09631 4 IKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLF---EMHDGKFHK----VANVVGNtmkYHPHGDASIYEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 89 VRMSQdwkaRHMLIEMHGNNGSV-DGDPPAAMRYTEARLSAIAAEMLrdIGKKTVEFVPNFDDQDMEPTVLPARFPNLLV 167
Cdd:PRK09631 77 VNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 168 NGSTGISAGYATDIPPHALDEVLDAVLMRLdkpnvtVDELMTVMkgPDFPTGGIIQGVDgikkaYETGRGKIIVRAQavV 247
Cdd:PRK09631 151 QGAEGIAVGMATKILPHNFNEILQAVKSEL------LGESFALY--PDFPTGGIVDVSE-----YADGNGKVLVRAK--I 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 248 EPIKggKEQIVITELPYDVNKANLVKKIDEQRVDKRLEgIAEIrdeSDRTGLRVVIELK--KDVPGQGILQYLFKTTDLQ 325
Cdd:PRK09631 216 ETKD--EKTIVIREIPFGTTTESLIASIEKAARKGKIK-ISSI---NDYTAENVEIEIKlpRGVYASEVIEALYAYTDCE 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 326 VAYNFNMIAIHNRRPTMMTLPLLLDAYIAHQKEVVTNRsiYDLQKAKDRSHIVDGLIKALSI---LDEVIATIRSSNDKK 402
Cdd:PRK09631 290 VSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKME--LELERAKLLEKIFAKTLEQIFIeerIYKRIETISSEEDVI 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 403 DAKLNLQEKF------DFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDKLIAKLEGILQS-EAKLVRVIKQELLDIKK 475
Cdd:PRK09631 368 SIVLSELKPFkeelsrDVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNLKSiKGYAINFIDKLLAKYSK 447
|
....*...
gi 1966496496 476 RFtePRRS 483
Cdd:PRK09631 448 EY--PRKT 453
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
18-281 |
5.96e-46 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 177.12 E-value: 5.96e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 18 DRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMFtegNTHDKPFRKsaktVGNVIGN---YHPHGDSSVYEAMVRMSQd 94
Cdd:PRK12758 29 NWFLDYASYVILERAVPHIEDGLKPVQRRILHSMK---EMDDGRYNK----VANVVGHtmqYHPHGDASIGDALVQLGQ- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 95 wkaRHMLIEMHGNNGSV-DGDPPAAMRYTEARLSAIAAEMLrdIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVNGSTGI 173
Cdd:PRK12758 101 ---KDLLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGI 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 174 SAGYATDIPPHALDEVLDAVLMRLDKPNVTVdelmtvmkGPDFPTGGIIQgvdgiKKAYETGR--GKIIVRAQAvvepIK 251
Cdd:PRK12758 176 AVGLSTKILPHNFNELIDASIAYLKGKEFKL--------YPDFPTGGIID-----VSNYNDGErgGRVRVRAKI----EK 238
|
250 260 270
....*....|....*....|....*....|....*....
gi 1966496496 252 GGKEQIVITELPYDVN---------KANLVKKIDEQRVD 281
Cdd:PRK12758 239 LDKKTLVITEIPYGTTtsslidsilKANDKGKIKIKKVE 277
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-349 |
8.00e-43 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 162.76 E-value: 8.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 12 LEEVMGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMF--TEGNTHdkpfrKSAKTVGNVIGnYHPHGDSSVYEAMV 89
Cdd:PRK09630 4 VSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFrmDDGKMH-----KVANIAGRTMA-LHPHGDAPIVEALV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 90 RMSQdwkaRHMLIEMHGNNGS-VDGDPPAAMRYTEARLSAIAAEMLrdIGKKTVEFVPNFDDQDMEPTVLPARFPNLLVN 168
Cdd:PRK09630 78 VLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLLLH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 169 GSTGISAGYATDIPPHALDEVLDAVLMRLDkpnvtvDELMTVMkgPDFPTGGIIQGVDgikkaYETGRGKIIVRAQAVVE 248
Cdd:PRK09630 152 GVDGIAVGMTTKIFPHNFCELLEAQIAILN------DQPFTLL--PDFPSGGTMDASE-----YQDGLGSITLRASIDII 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 249 PIKggkeQIVITELPYDVNKANLVKKIdEQRVDKRLEGIAEIRDESdrTGL-RVVIELKKDVPGQGILQYLFKTTDLQVA 327
Cdd:PRK09630 219 NDK----TLLIKEICPSTTTETLIRSI-ENAAKRGIIKIDSIQDFS--TDLpHIEIKLPKGIYAKDLLRPLFTHTECQVI 291
|
330 340
....*....|....*....|..
gi 1966496496 328 YNFNMIAIHNRRPTMMTLPLLL 349
Cdd:PRK09630 292 LTSRPTAIYQNKPVETSISEIL 313
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
23-447 |
1.03e-37 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 146.74 E-value: 1.03e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 23 YSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNV-IGNYHpHGDSSVYEAMVRMSQDWKARHML 101
Cdd:PHA02592 19 YAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVaDLGYH-HGETSAQDAGALMANTWNNNIPL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 102 IEMHGNNGSVDGDPPAAMRYTEARLSAIAAEMLRDIgkktvEFVPNFDDqdmEPTVLPARF----PNLLVNGSTGISAGY 177
Cdd:PHA02592 98 LDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDE-----DLAPVHED---PEHIPPAFYlpiiPMVLLNGVSGIATGY 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 178 ATDIPPHALDEVLDAVLMRLDKPNVTVDElmtvmkgPDFPtggiiqGVDGIKKAYETGRGKIIVRAQAVvepikgGKEQI 257
Cdd:PHA02592 170 ATNILPHSPKSVIKAVLAALNGKDITEPK-------VQFP------EFKGEVVEIEPGSYEIRGTYELN------GKTKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 258 VITELPYDVNKANLVKKIDeQRVDKRLegIAEIRDESDRtGLRVVIELKKDvpgqgilqYLFKTTDLQVAYNFNMIAIHN 337
Cdd:PHA02592 231 HITEIPVKYDRETYVAVLD-PLEEKGK--IVSYDDCTED-GFRFKVTLKRE--------ENEEATHEKIMKDFGLIERVS 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 338 RRPTMMT-----------LPLLLDaYIAHQKEVVTNRSIYDLQKAKDRshiVDGLIKALSILDEVIATIRSSNDKKDAKL 406
Cdd:PHA02592 299 QNITVINengklkvyenaEDLIRD-FVEIRKTYVQKRIQYEIKETEEA---FDLALAKAEFIKRVIAGEIVLQGKTRSEL 374
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1966496496 407 NLQ-EKFDFTEVQAEAIVSLQLYRLTNTDITELRQEQDELDK 447
Cdd:PHA02592 375 TEElSDNKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEK 416
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
23-121 |
4.40e-36 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 147.56 E-value: 4.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 23 YSKYIIQDRALPDARDGLKPVQRRILYAMFTEGNTHDKPFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKARHMLI 102
Cdd:NF038098 18 YAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLVRMAQPWSLRYPLV 97
|
90
....*....|....*....
gi 1966496496 103 EMHGNNGSVDGDPPAAMRY 121
Cdd:NF038098 98 DGQGNFGSPGNDPAAAMRY 116
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
23-455 |
2.09e-17 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 87.46 E-value: 2.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 23 YSKYIIqDRALPDARDGLKPVQRRILYAMFTEGNTHDKpfrKSAKTVGNVI--GNYHpHGDSSVYEAMVRMSQDWKARH- 99
Cdd:PLN03128 666 FSQADL-ARSIPSMVDGLKPSQRKVLFACFKRNLKSEI---KVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFVGSNn 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 100 -MLIEMHGNNGS--VDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVpNFDDQDMEPTVLPARFPNLLVNGSTGISAG 176
Cdd:PLN03128 741 iNLLTPSGQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGIGTG 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 177 YATDIPPHaldevldavlmrldKPNVTVDELMTVMKGPDFP---------TGGIIQGVDGIKKAYETGrgkiivraqAVV 247
Cdd:PLN03128 820 WSTFIPNY--------------NPRDIIANIRRLLRGEELEpmhpwyrgfKGTITEVSTSRSGSYTVT---------GII 876
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 248 EPIkgGKEQIVITELPYDVNKANLVKKIDE-QRVDKRLEG-IAEIRDESDRTGLRVVIELKK---DVPGQGILQYLFK-T 321
Cdd:PLN03128 877 EQI--GDTTIRITELPVRKWTQDYKEFLEAlLTGTKKKEPeIKDFKENHTDTTVHFTVTLSEekmARALAEGLEKKFKlS 954
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 322 TDLQV----AYNFNMIAIHNRRPTMMT---LPLLLDAYiAHQKEVVTNRSIYDLQKAKDRSHIVDGLIKA---------- 384
Cdd:PLN03128 955 TTISTsnmhLFDKDGKIKKYDSPEDILeefFHLRLDLY-VKRKEVLLENLEYELKKLDNKARFILAVVKGeivvnnrkra 1033
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 385 --LSILDEVIATIRSSNDKKDAKLNLQEKFDFTEVQAEAI-----------VSLQLYRLTNTDITELRQEQDELDKLIAK 451
Cdd:PLN03128 1034 elLAELEEKGFDKFPKTAKISETNVVGDRDGEASEEEEASdnelaksydylLGMPISSLTLEKVDELRAERAKKETEVEE 1113
|
....
gi 1966496496 452 LEGI 455
Cdd:PLN03128 1114 LKKT 1117
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
31-483 |
2.45e-15 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 80.86 E-value: 2.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 31 RALPDARDGLKPVQRRILYAMFTEGNTHDKpfrKSAKTVGNV--IGNYHpHGDSSVYEAMVRMSQDWkarhmlieMHGNN 108
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACFKRNLKNEI---KVAQLSGYVseHSAYH-HGEQSLQQTIVGMAQNF--------VGSNN 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 109 ----------GS--VDGDPPAAMRYTEARLSAIAaemlRDIGKKTVEFVPNF---DDQDMEPTVLPARFPNLLVNGSTGI 173
Cdd:PTZ00108 748 inllypcgqfGSrlQGGKDHAAARYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPFYYVPIIPMVLVNGAEGI 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 174 SAGYATDIPPHALDEVLDAVLMRLDkpNVTVDELMTVMKGPDfptgGIIQgvdgikkayETGRGKIIVRAQAVVEPikgg 253
Cdd:PTZ00108 824 GTGFSTSIPNYNPLDIIDNLRRRLN--GEEVRPLVPWYRGFK----GTIE---------RNPKGKFISKGIYEKVP---- 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 254 KEQIVITELPYDVNKANLVKKIDEQRVDKRLEgIAEIRDESdrTGLRVVIELK------KDVPGQGILQYlFKTTdlQVA 327
Cdd:PTZ00108 885 DGTVEITELPIGKWTEDYKEFLESETLKEKDV-IVDYRDYS--TANTVHFTVKlndgvlEQWEEEGIEKV-FKLK--STI 958
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 328 YNFNMIAI--HNRRPTMMTLPLLLDAYIAHQKEVVTNRSIY---DLQKAKDR--------SHIVDG-----------LIK 383
Cdd:PTZ00108 959 STTNMVLFdeNGKIKKYSDALDILKEFYLVRLDLYKKRKEYllgKLERELARlsnkvrfiKHVINGelvitnakkkdLVK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 384 ALS--ILDEV--IATIRSSNDKKDAKLNLQEKFDFTEVQAEAIV----------SLQLYRLTNTDITELRQE----QDEL 445
Cdd:PTZ00108 1039 ELKklGYVRFkdIIKKKSEKITAEEEEGAEEDDEADDEDDEEELgaavsydyllSMPIWSLTKEKVEKLNAElekkEKEL 1118
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 1966496496 446 DKLIAK-------------LEGILQSEAKLVRVIKQELLDIKKRFTEPRRS 483
Cdd:PTZ00108 1119 EKLKNTtpkdmwledldkfEEALEEQEEVEEKEIAKEQRLKSKTKGKASKL 1169
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
31-211 |
1.17e-11 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 68.74 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 31 RALPDARDGLKPVQRRILYAMFTegnthdKPFRKSAKT---VGNV--IGNYHpHGDSSVYEAMVRMSQDWKARHM--LIE 103
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFK------RNFVKEAKVaqlSGYVseHSAYH-HGEQSLASTIIGMAQDFVGSNNinLLL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1966496496 104 MHGNNG--SVDGDPPAAMRYTEARLSAIAAEMLRDIGKKTVEFVpNFDDQDMEPTVLPARFPNLLVNGSTGISAGYATDI 181
Cdd:PLN03237 771 PNGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFI 849
|
170 180 190
....*....|....*....|....*....|
gi 1966496496 182 PPHALDEVLDAVLMRLDkpnvtvDELMTVM 211
Cdd:PLN03237 850 PNYNPRDIVANIRRLLN------GESMEPM 873
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
656-701 |
2.71e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 50.56 E-value: 2.71e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1966496496 656 ELMLTTDTAYAIRFPMEELPVTGVKTGGVKGITLKDGEALVGVNVL 701
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
707-752 |
5.82e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 38.24 E-value: 5.82e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1966496496 707 QYVVIVTQRGAVKKMNVAEVEVAGRAKRGLKVLTeLKANpHRIVAV 752
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN-LKEG-DKVVSV 44
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
549-595 |
9.24e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 37.85 E-value: 9.24e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1966496496 549 HHLLLFTNRGNYIYQPVHELPDIRWKDLGQHISSIvptGEDESIIAV 595
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINL---KEGDKVVSV 44
|
|
| |
