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Conserved domains on  [gi|1994267217|ref|WP_205229395|]
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Panacea domain-containing protein [Desulfobulbus rhabdoformis]

Protein Classification

Panacea domain-containing protein( domain architecture ID 10007595)

Panacea domain-containing protein may function as an antitoxin component in a type II toxin-antitoxin system, neutralizing a toxin that may act as a translation inhibitor, a membrane disruptor, or via some other mechanism.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
 1-134 5.22e-32

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


:

Pssm-ID: 442819  Cd Length: 146  Bit Score: 113.15  E-value: 5.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1994267217   1 MKVNAIKLAGFILSAYPNV--PIYPMKLQKLAYYAKVWSIV-ANKNFIDADFERWDYGPVNREIYSAYREYSKEIIPCPS 77
Cdd:COG3600     1 MSISALDVANYFLSKANEDggSLTPLKLQKLLYYAQGWHLAlYGRPLFDEDFEAWKYGPVVPELYDEYKDFGSNPIPEPK 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1994267217  78 E--PVSLEPEQEDFIKFVLDNYIDQSAVALSIQTHNEDPWINT-------DHNGIISEREIINYYS 134
Cdd:COG3600    81 EfdDSELSEEEKEILDEVWEKYGKYSAWELSELTHSESPWKKArkglgaeGSNNVISDEDIKEYFK 146
 
Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
 1-134 5.22e-32

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


Pssm-ID: 442819  Cd Length: 146  Bit Score: 113.15  E-value: 5.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1994267217   1 MKVNAIKLAGFILSAYPNV--PIYPMKLQKLAYYAKVWSIV-ANKNFIDADFERWDYGPVNREIYSAYREYSKEIIPCPS 77
Cdd:COG3600     1 MSISALDVANYFLSKANEDggSLTPLKLQKLLYYAQGWHLAlYGRPLFDEDFEAWKYGPVVPELYDEYKDFGSNPIPEPK 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1994267217  78 E--PVSLEPEQEDFIKFVLDNYIDQSAVALSIQTHNEDPWINT-------DHNGIISEREIINYYS 134
Cdd:COG3600    81 EfdDSELSEEEKEILDEVWEKYGKYSAWELSELTHSESPWKKArkglgaeGSNNVISDEDIKEYFK 146
DUF4065 pfam13274
Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. ...
 26-74 7.97e-05

Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.


Pssm-ID: 433077  Cd Length: 108  Bit Score: 40.47  E-value: 7.97e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1994267217  26 LQKLAYYAKVWS-IVANKNFIDADFERWDYGPVNREIYSAYREYSKEIIP 74
Cdd:pfam13274   1 LQKLLYFADGLHlKKYGKPITGDEYEAWKYGPVVPDVYDLIKGYGGNPIE 50
 
Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
 1-134 5.22e-32

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


Pssm-ID: 442819  Cd Length: 146  Bit Score: 113.15  E-value: 5.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1994267217   1 MKVNAIKLAGFILSAYPNV--PIYPMKLQKLAYYAKVWSIV-ANKNFIDADFERWDYGPVNREIYSAYREYSKEIIPCPS 77
Cdd:COG3600     1 MSISALDVANYFLSKANEDggSLTPLKLQKLLYYAQGWHLAlYGRPLFDEDFEAWKYGPVVPELYDEYKDFGSNPIPEPK 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1994267217  78 E--PVSLEPEQEDFIKFVLDNYIDQSAVALSIQTHNEDPWINT-------DHNGIISEREIINYYS 134
Cdd:COG3600    81 EfdDSELSEEEKEILDEVWEKYGKYSAWELSELTHSESPWKKArkglgaeGSNNVISDEDIKEYFK 146
DUF4065 pfam13274
Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. ...
 26-74 7.97e-05

Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.


Pssm-ID: 433077  Cd Length: 108  Bit Score: 40.47  E-value: 7.97e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1994267217  26 LQKLAYYAKVWS-IVANKNFIDADFERWDYGPVNREIYSAYREYSKEIIP 74
Cdd:pfam13274   1 LQKLLYFADGLHlKKYGKPITGDEYEAWKYGPVVPDVYDLIKGYGGNPIE 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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