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Conserved domains on  [gi|1999525139|ref|WP_206712438|]
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thrombospondin type 3 repeat-containing protein [Myxococcus landrumus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
myxo_dep_M36 super family cl45606
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 292-442 6.01e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


The actual alignment was detected with superfamily member NF038112:

Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 39.25  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  292 DPKAPFTVSAGGTAKL-ANAGDGlrpplfanrNGAAMEYRWTVSKRPegsnavvenpqgAVTLSRDwqytyvDGSVPHFV 370
Cdd:NF038112  1473 HAGESITVDEGSTVTLdASATDP---------DGDTLTYAWTQVAGP------------SVTLTGA------DSAKLTFT 1525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  371 -PDSDGTYELTvearlaFADRVFpDQRVSTSTLVLTV----GKGDGDGPNCSSvpAGFSITA---LGAALLGVLMRRRRR 442
Cdd:NF038112  1526 aPEVSADTTLT------FSLTVT-DGSGSSGPVVVTVtvknVNRAPDGGGCSS--TGGSPGGmlpLLLLLAALALSRRRR 1596
 
Name Accession Description Interval E-value
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 292-442 6.01e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 39.25  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  292 DPKAPFTVSAGGTAKL-ANAGDGlrpplfanrNGAAMEYRWTVSKRPegsnavvenpqgAVTLSRDwqytyvDGSVPHFV 370
Cdd:NF038112  1473 HAGESITVDEGSTVTLdASATDP---------DGDTLTYAWTQVAGP------------SVTLTGA------DSAKLTFT 1525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  371 -PDSDGTYELTvearlaFADRVFpDQRVSTSTLVLTV----GKGDGDGPNCSSvpAGFSITA---LGAALLGVLMRRRRR 442
Cdd:NF038112  1526 aPEVSADTTLT------FSLTVT-DGSGSSGPVVVTVtvknVNRAPDGGGCSS--TGGSPGGmlpLLLLLAALALSRRRR 1596
 
Name Accession Description Interval E-value
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 292-442 6.01e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 39.25  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  292 DPKAPFTVSAGGTAKL-ANAGDGlrpplfanrNGAAMEYRWTVSKRPegsnavvenpqgAVTLSRDwqytyvDGSVPHFV 370
Cdd:NF038112  1473 HAGESITVDEGSTVTLdASATDP---------DGDTLTYAWTQVAGP------------SVTLTGA------DSAKLTFT 1525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1999525139  371 -PDSDGTYELTvearlaFADRVFpDQRVSTSTLVLTV----GKGDGDGPNCSSvpAGFSITA---LGAALLGVLMRRRRR 442
Cdd:NF038112  1526 aPEVSADTTLT------FSLTVT-DGSGSSGPVVVTVtvknVNRAPDGGGCSS--TGGSPGGmlpLLLLLAALALSRRRR 1596
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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