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penicillin-binding protein 2 [Chloracidobacterium aggregatum]
Protein Classification
penicillin-binding protein 2 ( domain architecture ID 11496821 )
penicillin-binding protein (PBP) 2 is a membrane-associated enzyme that is involved in the synthesis of cross-linked peptidoglycan
List of domain hits
Name
Accession
Description
Interval
E-value
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
17-609
0e+00
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 651.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R L L A L QAGIV A A F V VLA L RL WSM QV VHH E D Y VKQA E N NR E R KI PI VA PRG N ILDR H G NV L V D S RP T FSL MVNR E DIQ D EA 96
Cdd:TIGR03423 2 R A L V L GGLVL A L F G VLA A RL FYL QV IRG E E Y ATLS E D NR I R LV PI PP PRG L ILDR N G VL L A D N RP S FSL EIVP E KVD D LD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TL RI LA EEFGVA PE YARQQ L RSPAART R -- P VEV KS NI T DADR A KVS V LD Y EH P EFLV E L R PQ R K YP H GELA C H I LGYV 174
Cdd:TIGR03423 82 A TL DR LA KLLDLD PE DIARF L KELKRSR R fe P IPL KS DL T EEEV A RFA V NQ Y RL P GVEI E A R LK R Y YP Y GELA A H V LGYV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 175 T E VS E AQ L K R P E FDYCRP GD KV G QA G L E RF Y NRI L M G RD GYR RII V DR RGR FV R EIET VPP IA G Q D I V T T L D LD LQ RV AE 254
Cdd:TIGR03423 162 G E IN E ED L E R L E PANYAG GD YI G KS G I E KY Y EDE L R G KP GYR EVE V NA RGR VI R TLSR VPP VP G K D L V L T I D AR LQ QA AE 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 255 ER L KALK ln G TIA VMDPR N GE M LA LA S M P GY DPNLF AG GIS RA DY ARYA ND KHK PL R NRAIQ DI YPPGST W K IIM A V A GM 334
Cdd:TIGR03423 242 KA L GGRR -- G AVV VMDPR T GE I LA MV S T P SF DPNLF VD GIS SK DY KALL ND PDR PL L NRAIQ GV YPPGST F K PVV A L A AL 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 335 RA GV LK P TD R LL C G G GINV GGR HV RC -- M G S HG TPP L ST AI AK SCD GW FY R L GIK LG L D NLRT YA SEL G A G EY TGIDLP N 412
Cdd:TIGR03423 320 EE GV IT P ET R IY C P G YFQL GGR RF RC wk R G G HG RVD L RK AI EE SCD VY FY Q L ALR LG I D KIAE YA KRF G F G QK TGIDLP G 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 413 E FK G YI PS L E L K AATVRR tmpnatpaqy R W TDA D SVYA SIGQ AM V RP TPLQ MLRSV A GI A MR G EFHT PH FLLEARPTQER 492
Cdd:TIGR03423 400 E KS G LV PS R E W K RKRFGQ ---------- P W YPG D TLNV SIGQ GY V LV TPLQ LAVAT A AL A NG G KLYK PH LVKSIEDPDGG 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 493 PGVTFKDQ V K R - IELPDDYWEA V I EGM WGA VN - A GGTA SGSA L rdp ETGFE M C GKTGTAQVVS ----- K LK A SKL -- EE R 563
Cdd:TIGR03423 470 VVRRTEPE V L R p LPISPENLDV V R EGM RDV VN g P GGTA RRAR L --- GLPYK M A GKTGTAQVVS lkqge K YD A EQI pe RL R 546
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 2035176090 564 DH SW FV G F G P REK P E IA AISL VEHGG F G AK A S AP NV R AVFEVW L RK 609
Cdd:TIGR03423 547 DH AL FV A F A P YDN P K IA VAVI VEHGG G G SS A A AP IA R KIMDAY L LG 592
Name
Accession
Description
Interval
E-value
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
17-609
0e+00
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 651.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R L L A L QAGIV A A F V VLA L RL WSM QV VHH E D Y VKQA E N NR E R KI PI VA PRG N ILDR H G NV L V D S RP T FSL MVNR E DIQ D EA 96
Cdd:TIGR03423 2 R A L V L GGLVL A L F G VLA A RL FYL QV IRG E E Y ATLS E D NR I R LV PI PP PRG L ILDR N G VL L A D N RP S FSL EIVP E KVD D LD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TL RI LA EEFGVA PE YARQQ L RSPAART R -- P VEV KS NI T DADR A KVS V LD Y EH P EFLV E L R PQ R K YP H GELA C H I LGYV 174
Cdd:TIGR03423 82 A TL DR LA KLLDLD PE DIARF L KELKRSR R fe P IPL KS DL T EEEV A RFA V NQ Y RL P GVEI E A R LK R Y YP Y GELA A H V LGYV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 175 T E VS E AQ L K R P E FDYCRP GD KV G QA G L E RF Y NRI L M G RD GYR RII V DR RGR FV R EIET VPP IA G Q D I V T T L D LD LQ RV AE 254
Cdd:TIGR03423 162 G E IN E ED L E R L E PANYAG GD YI G KS G I E KY Y EDE L R G KP GYR EVE V NA RGR VI R TLSR VPP VP G K D L V L T I D AR LQ QA AE 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 255 ER L KALK ln G TIA VMDPR N GE M LA LA S M P GY DPNLF AG GIS RA DY ARYA ND KHK PL R NRAIQ DI YPPGST W K IIM A V A GM 334
Cdd:TIGR03423 242 KA L GGRR -- G AVV VMDPR T GE I LA MV S T P SF DPNLF VD GIS SK DY KALL ND PDR PL L NRAIQ GV YPPGST F K PVV A L A AL 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 335 RA GV LK P TD R LL C G G GINV GGR HV RC -- M G S HG TPP L ST AI AK SCD GW FY R L GIK LG L D NLRT YA SEL G A G EY TGIDLP N 412
Cdd:TIGR03423 320 EE GV IT P ET R IY C P G YFQL GGR RF RC wk R G G HG RVD L RK AI EE SCD VY FY Q L ALR LG I D KIAE YA KRF G F G QK TGIDLP G 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 413 E FK G YI PS L E L K AATVRR tmpnatpaqy R W TDA D SVYA SIGQ AM V RP TPLQ MLRSV A GI A MR G EFHT PH FLLEARPTQER 492
Cdd:TIGR03423 400 E KS G LV PS R E W K RKRFGQ ---------- P W YPG D TLNV SIGQ GY V LV TPLQ LAVAT A AL A NG G KLYK PH LVKSIEDPDGG 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 493 PGVTFKDQ V K R - IELPDDYWEA V I EGM WGA VN - A GGTA SGSA L rdp ETGFE M C GKTGTAQVVS ----- K LK A SKL -- EE R 563
Cdd:TIGR03423 470 VVRRTEPE V L R p LPISPENLDV V R EGM RDV VN g P GGTA RRAR L --- GLPYK M A GKTGTAQVVS lkqge K YD A EQI pe RL R 546
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 2035176090 564 DH SW FV G F G P REK P E IA AISL VEHGG F G AK A S AP NV R AVFEVW L RK 609
Cdd:TIGR03423 547 DH AL FV A F A P YDN P K IA VAVI VEHGG G G SS A A AP IA R KIMDAY L LG 592
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
6-611
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 575.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 6 SGPPPSFNP R L RLL A L QAGIVAA F VV L AL RL WSM QVV HHED Y VKQ AE N NR E R KI PI V APRG N I L DR H GNVL VDSR P TF SL 85
Cdd:COG0768 2 KRKKEKRLF R R RLL L L FLLVLLL F LL L VG RL FYL QVV EGDE Y AEL AE E NR I R TV PI P APRG L I Y DR N GNVL ATNV P VY SL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 86 MVNR E DIQ D EA ET LRI LA EEF G VA PE YA R QQ L RS pa ARTR PV EV K S N ITDADR A KVSV L DY eh P EFL VE LRPQ R K YP H GE 165
Cdd:COG0768 82 YADP E EVK D PE ET AEK LA KLL G LD PE EL R KK L KK -- KSRF PV YL K R N LSPEEA A RIRA L KL -- P GVY VE AEYK R Y YP Y GE 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 166 LA C H I LGYV T E VS eaqlkrpefdycr P GD KV G QA GLE RF Y NRI L M G RD G Y RR II VD R RGR FV R EI - E TV PP IA G Q D I V T T 244
Cdd:COG0768 158 LA A H V LGYV G E IN ------------- G GD GI G KS GLE KA Y EDL L R G TP G K RR VE VD A RGR VI R DL g E EK PP VP G K D L V L T 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 245 L D L DLQ RV AEE R L - KA LKLN ---- G TIA VMDP RN GE M LA L AS M P GY DPNLF A GG isradyaryand KHK PLRNRA I Q DI Y 319
Cdd:COG0768 225 I D S DLQ KI AEE A L k KA VEEY kaks G AVV VMDP KT GE I LA M AS Y P SF DPNLF V GG ------------ PDE PLRNRA V Q GT Y 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 320 P PGST W K IIM A V A GMRA GV LK P TDRLL C G G GIN VGGR HV R CMGSH G TPP L S -- T A I AKS CDGW FY R L GIK LG L D N L RT Y A 397
Cdd:COG0768 293 E PGST F K PFT A A A ALEE GV IT P DTTFD C P G YYR VGGR TI R DWDRG G HGT L T lt E A L AKS SNVG FY K L ALR LG I D K L YD Y L 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 398 SEL G A G EY TGIDLP N E FK G YI PS LE lkaatvrrtmpnatpaqy RW TDADSVYA SIGQ AM - V rp TPLQ MLRSV A G IA MR G E 476
Cdd:COG0768 373 KKF G L G QK TGIDLP G E AS G LL PS PK ------------------ RW YPGETATM SIGQ GL s V -- TPLQ LAQAY A A IA NG G V 432
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 477 FHT PH FLL E ARPTQERPGVTFKDQVK R I e LPDDYW E A V I EGM W G A VN - A GGTA SGS A L rdpe T G FEMC GKTGTAQVV SKL 555
Cdd:COG0768 433 LVK PH LVK E IVDPDGEVVKEEPEVLR R V - ISPETA E T V R EGM E G V VN e P GGTA RRA A I ---- P G YRVA GKTGTAQVV DIG 507
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 2035176090 556 KASKLEE R DHSW FVGF G P REK P EI A AISL VE HG G --- F G AKAS AP NV R AVF E VW LR KKK 611
Cdd:COG0768 508 NGGYYKG R HIAS FVGF A P ADN P RY A VAVV VE NP G gga Y G GTVA AP VF R EIM E AY LR LLG 566
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
17-591
6.07e-106
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 334.04
E-value: 6.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R L L ALQA GI VAAFV VL ALR L WSM Q V V HHE DY VKQAEN NR ERKI PI VAP RG N I L DR H G NV L VDS R PTFS L MVNR E DIQDEA 96
Cdd:PRK10795 21 R A L VAFL GI LLLTG VL IAN L YNL Q I V RFT DY QTRSNE NR IKLV PI APS RG I I Y DR N G TP L ALN R TIYQ L EMMP E KVDNLQ 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TL RI L AEEFGVAPE -- Y A RQQL R SPAA R TRPVE VK S N I T DADR A KVS V LD Y EH P EFL V ELRPQ R K YP H G ELAC H IL GYV 174
Cdd:PRK10795 101 Q TL DA L RSVVDLTDD di A A FRKE R ARSR R FTSIP VK T N L T EVQV A RFA V NQ Y RF P GVE V KGYQR R Y YP Y G SALT H VI GYV 180
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 175 TEVSEAQLK R PE ----- FD Y CRPG D k V G QA G L ER F Y NRI L M G RD GY RRII V DR RGR FV R EIETV PP I AG Q DI VT TLDL D L 249
Cdd:PRK10795 181 SKINDKDVE R LD kegkl AN Y AATH D - I G KL G I ER Y Y EDV L H G KT GY EEVE V NN RGR VI R QLHEQ PP Q AG H DI YL TLDL K L 259
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 250 Q RVA E ER L KALK ln GTIA V M DPR N G EM LAL A S M P G YDPNLF AG GIS RA DY ARYA ND KHK PL R NRA I Q DI YPP G ST W K IIM 329
Cdd:PRK10795 260 Q QYI E TL L AGSR -- AAVV V T DPR T G GI LAL V S T P S YDPNLF VD GIS SK DY SGLL ND PNR PL I NRA T Q GV YPP A ST V K PYV 337
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 330 AV AGMR AGV LKPTDR L LCG G GINVG G RHV R CMG ---- S HG TPPLSTAIAK S C D GW FY RLGIKL G L D N L RTYASEL G A G E Y 405
Cdd:PRK10795 338 AV SALS AGV ITRNTS L FDP G WWQLP G SEK R YRD wkkw G HG RLNVTKSLEE S A D TF FY QVAYDM G I D R L SEWMGKF G Y G H Y 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 406 TGIDL PN E FK G YI P SL E L K AA tv R RTM P natpaqyr W TDA D SVYAS IGQ AMVRP TP L QM LRSVAGIAMR G EFHT PH F L LE 485
Cdd:PRK10795 418 TGIDL AE E RS G NM P TR E W K QK -- R FKK P -------- W YQG D TIPVG IGQ GYWTA TP I QM SKALMTLIND G IVKV PH L L MS 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 486 ARPTQERPGVTFKDQVKRIELPDD YWE AVIE GM W G AV N - AG GTA SGSALRD P etg FEMCG K T GTAQV VS ----- KLK A S K 559
Cdd:PRK10795 488 TAEDGKQVPWVQPHEPPVGDIHSG YWE IAKD GM Y G VA N r PN GTA HKYFASA P --- YKIAA K S GTAQV FG lkane TYN A H K 564
570 580 590
....*....|....*....|....*....|....
gi 2035176090 560 LE E -- RDH SWFVG F G P REK P EI A AISLV E H GG F G 591
Cdd:PRK10795 565 IA E rl RDH KLMTA F A P YNN P QV A VAIIL E N GG A G 598
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
264-604
5.30e-58
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 197.25
E-value: 5.30e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 264 G TIA V M DP RN GE M LA LASM P G YDPN L F A G gisradyaryandkhk PLRNRA IQDI Y P PGST W K IIM A V A GMRA GVLKP TD 343
Cdd:pfam00905 1 G SAV V L DP KT GE V LA MVGK P S YDPN G F I G ---------------- PLRNRA VTSR Y E PGST F K PFT A L A ALDN GVLKP DE 64
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 344 RLLCGG G INV GG RHVRCMGS -- H G TPP L ST A IAK S CDGWFYR L GI KLG L D N LR T Y ASEL G A G EY TGI D LP N E FK GY IPS l 421
Cdd:pfam00905 65 TIFDWP G KQQ GG KSIGDWNQ dq V G IGT L RQ A LEY S SNWYMQK L AQ KLG A D K LR S Y LKKF G Y G NK TGI G LP G E NA GY LTP - 143
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 422 elkaatvrrtmpnatpaqy R W TDADSVYAS IG QAM vrp TPLQ MLRSV A G IA MR G EFHT PH FLLEARPTQERP gvtfkd QV 501
Cdd:pfam00905 144 ------------------- Y W LEGATASFG IG LTI --- TPLQ QAQAY A A IA NG G KLVP PH LVKSIEDKVDPK ------ VL 195
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 502 KRIELPDDYW E A V IEGMWGA VN A G G ta SGSALRD P et G FEMC GKTGTAQV VSKLKASKLEERDHS WFVG FG P REK P EI A A 581
Cdd:pfam00905 196 NKLPISKSTA E K V KDMLRLV VN D G T -- GTGTAAV P -- G YKVA GKTGTAQV AGPKGGGYYDGAQIG WFVG YA P ADN P KY A F 271
330 340
....*....|....*....|....*
gi 2035176090 582 IS L VEHGG -- F G A K AS AP NVRAVF E 604
Cdd:pfam00905 272 AV L IDDPK ry Y G G K VA AP IFKDIL E 296
Name
Accession
Description
Interval
E-value
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
17-609
0e+00
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 651.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R L L A L QAGIV A A F V VLA L RL WSM QV VHH E D Y VKQA E N NR E R KI PI VA PRG N ILDR H G NV L V D S RP T FSL MVNR E DIQ D EA 96
Cdd:TIGR03423 2 R A L V L GGLVL A L F G VLA A RL FYL QV IRG E E Y ATLS E D NR I R LV PI PP PRG L ILDR N G VL L A D N RP S FSL EIVP E KVD D LD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TL RI LA EEFGVA PE YARQQ L RSPAART R -- P VEV KS NI T DADR A KVS V LD Y EH P EFLV E L R PQ R K YP H GELA C H I LGYV 174
Cdd:TIGR03423 82 A TL DR LA KLLDLD PE DIARF L KELKRSR R fe P IPL KS DL T EEEV A RFA V NQ Y RL P GVEI E A R LK R Y YP Y GELA A H V LGYV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 175 T E VS E AQ L K R P E FDYCRP GD KV G QA G L E RF Y NRI L M G RD GYR RII V DR RGR FV R EIET VPP IA G Q D I V T T L D LD LQ RV AE 254
Cdd:TIGR03423 162 G E IN E ED L E R L E PANYAG GD YI G KS G I E KY Y EDE L R G KP GYR EVE V NA RGR VI R TLSR VPP VP G K D L V L T I D AR LQ QA AE 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 255 ER L KALK ln G TIA VMDPR N GE M LA LA S M P GY DPNLF AG GIS RA DY ARYA ND KHK PL R NRAIQ DI YPPGST W K IIM A V A GM 334
Cdd:TIGR03423 242 KA L GGRR -- G AVV VMDPR T GE I LA MV S T P SF DPNLF VD GIS SK DY KALL ND PDR PL L NRAIQ GV YPPGST F K PVV A L A AL 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 335 RA GV LK P TD R LL C G G GINV GGR HV RC -- M G S HG TPP L ST AI AK SCD GW FY R L GIK LG L D NLRT YA SEL G A G EY TGIDLP N 412
Cdd:TIGR03423 320 EE GV IT P ET R IY C P G YFQL GGR RF RC wk R G G HG RVD L RK AI EE SCD VY FY Q L ALR LG I D KIAE YA KRF G F G QK TGIDLP G 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 413 E FK G YI PS L E L K AATVRR tmpnatpaqy R W TDA D SVYA SIGQ AM V RP TPLQ MLRSV A GI A MR G EFHT PH FLLEARPTQER 492
Cdd:TIGR03423 400 E KS G LV PS R E W K RKRFGQ ---------- P W YPG D TLNV SIGQ GY V LV TPLQ LAVAT A AL A NG G KLYK PH LVKSIEDPDGG 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 493 PGVTFKDQ V K R - IELPDDYWEA V I EGM WGA VN - A GGTA SGSA L rdp ETGFE M C GKTGTAQVVS ----- K LK A SKL -- EE R 563
Cdd:TIGR03423 470 VVRRTEPE V L R p LPISPENLDV V R EGM RDV VN g P GGTA RRAR L --- GLPYK M A GKTGTAQVVS lkqge K YD A EQI pe RL R 546
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 2035176090 564 DH SW FV G F G P REK P E IA AISL VEHGG F G AK A S AP NV R AVFEVW L RK 609
Cdd:TIGR03423 547 DH AL FV A F A P YDN P K IA VAVI VEHGG G G SS A A AP IA R KIMDAY L LG 592
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
6-611
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 575.62
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 6 SGPPPSFNP R L RLL A L QAGIVAA F VV L AL RL WSM QVV HHED Y VKQ AE N NR E R KI PI V APRG N I L DR H GNVL VDSR P TF SL 85
Cdd:COG0768 2 KRKKEKRLF R R RLL L L FLLVLLL F LL L VG RL FYL QVV EGDE Y AEL AE E NR I R TV PI P APRG L I Y DR N GNVL ATNV P VY SL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 86 MVNR E DIQ D EA ET LRI LA EEF G VA PE YA R QQ L RS pa ARTR PV EV K S N ITDADR A KVSV L DY eh P EFL VE LRPQ R K YP H GE 165
Cdd:COG0768 82 YADP E EVK D PE ET AEK LA KLL G LD PE EL R KK L KK -- KSRF PV YL K R N LSPEEA A RIRA L KL -- P GVY VE AEYK R Y YP Y GE 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 166 LA C H I LGYV T E VS eaqlkrpefdycr P GD KV G QA GLE RF Y NRI L M G RD G Y RR II VD R RGR FV R EI - E TV PP IA G Q D I V T T 244
Cdd:COG0768 158 LA A H V LGYV G E IN ------------- G GD GI G KS GLE KA Y EDL L R G TP G K RR VE VD A RGR VI R DL g E EK PP VP G K D L V L T 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 245 L D L DLQ RV AEE R L - KA LKLN ---- G TIA VMDP RN GE M LA L AS M P GY DPNLF A GG isradyaryand KHK PLRNRA I Q DI Y 319
Cdd:COG0768 225 I D S DLQ KI AEE A L k KA VEEY kaks G AVV VMDP KT GE I LA M AS Y P SF DPNLF V GG ------------ PDE PLRNRA V Q GT Y 292
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 320 P PGST W K IIM A V A GMRA GV LK P TDRLL C G G GIN VGGR HV R CMGSH G TPP L S -- T A I AKS CDGW FY R L GIK LG L D N L RT Y A 397
Cdd:COG0768 293 E PGST F K PFT A A A ALEE GV IT P DTTFD C P G YYR VGGR TI R DWDRG G HGT L T lt E A L AKS SNVG FY K L ALR LG I D K L YD Y L 372
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 398 SEL G A G EY TGIDLP N E FK G YI PS LE lkaatvrrtmpnatpaqy RW TDADSVYA SIGQ AM - V rp TPLQ MLRSV A G IA MR G E 476
Cdd:COG0768 373 KKF G L G QK TGIDLP G E AS G LL PS PK ------------------ RW YPGETATM SIGQ GL s V -- TPLQ LAQAY A A IA NG G V 432
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 477 FHT PH FLL E ARPTQERPGVTFKDQVK R I e LPDDYW E A V I EGM W G A VN - A GGTA SGS A L rdpe T G FEMC GKTGTAQVV SKL 555
Cdd:COG0768 433 LVK PH LVK E IVDPDGEVVKEEPEVLR R V - ISPETA E T V R EGM E G V VN e P GGTA RRA A I ---- P G YRVA GKTGTAQVV DIG 507
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 2035176090 556 KASKLEE R DHSW FVGF G P REK P EI A AISL VE HG G --- F G AKAS AP NV R AVF E VW LR KKK 611
Cdd:COG0768 508 NGGYYKG R HIAS FVGF A P ADN P RY A VAVV VE NP G gga Y G GTVA AP VF R EIM E AY LR LLG 566
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
17-591
6.07e-106
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 334.04
E-value: 6.07e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R L L ALQA GI VAAFV VL ALR L WSM Q V V HHE DY VKQAEN NR ERKI PI VAP RG N I L DR H G NV L VDS R PTFS L MVNR E DIQDEA 96
Cdd:PRK10795 21 R A L VAFL GI LLLTG VL IAN L YNL Q I V RFT DY QTRSNE NR IKLV PI APS RG I I Y DR N G TP L ALN R TIYQ L EMMP E KVDNLQ 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TL RI L AEEFGVAPE -- Y A RQQL R SPAA R TRPVE VK S N I T DADR A KVS V LD Y EH P EFL V ELRPQ R K YP H G ELAC H IL GYV 174
Cdd:PRK10795 101 Q TL DA L RSVVDLTDD di A A FRKE R ARSR R FTSIP VK T N L T EVQV A RFA V NQ Y RF P GVE V KGYQR R Y YP Y G SALT H VI GYV 180
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 175 TEVSEAQLK R PE ----- FD Y CRPG D k V G QA G L ER F Y NRI L M G RD GY RRII V DR RGR FV R EIETV PP I AG Q DI VT TLDL D L 249
Cdd:PRK10795 181 SKINDKDVE R LD kegkl AN Y AATH D - I G KL G I ER Y Y EDV L H G KT GY EEVE V NN RGR VI R QLHEQ PP Q AG H DI YL TLDL K L 259
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 250 Q RVA E ER L KALK ln GTIA V M DPR N G EM LAL A S M P G YDPNLF AG GIS RA DY ARYA ND KHK PL R NRA I Q DI YPP G ST W K IIM 329
Cdd:PRK10795 260 Q QYI E TL L AGSR -- AAVV V T DPR T G GI LAL V S T P S YDPNLF VD GIS SK DY SGLL ND PNR PL I NRA T Q GV YPP A ST V K PYV 337
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 330 AV AGMR AGV LKPTDR L LCG G GINVG G RHV R CMG ---- S HG TPPLSTAIAK S C D GW FY RLGIKL G L D N L RTYASEL G A G E Y 405
Cdd:PRK10795 338 AV SALS AGV ITRNTS L FDP G WWQLP G SEK R YRD wkkw G HG RLNVTKSLEE S A D TF FY QVAYDM G I D R L SEWMGKF G Y G H Y 417
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 406 TGIDL PN E FK G YI P SL E L K AA tv R RTM P natpaqyr W TDA D SVYAS IGQ AMVRP TP L QM LRSVAGIAMR G EFHT PH F L LE 485
Cdd:PRK10795 418 TGIDL AE E RS G NM P TR E W K QK -- R FKK P -------- W YQG D TIPVG IGQ GYWTA TP I QM SKALMTLIND G IVKV PH L L MS 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 486 ARPTQERPGVTFKDQVKRIELPDD YWE AVIE GM W G AV N - AG GTA SGSALRD P etg FEMCG K T GTAQV VS ----- KLK A S K 559
Cdd:PRK10795 488 TAEDGKQVPWVQPHEPPVGDIHSG YWE IAKD GM Y G VA N r PN GTA HKYFASA P --- YKIAA K S GTAQV FG lkane TYN A H K 564
570 580 590
....*....|....*....|....*....|....
gi 2035176090 560 LE E -- RDH SWFVG F G P REK P EI A AISLV E H GG F G 591
Cdd:PRK10795 565 IA E rl RDH KLMTA F A P YNN P QV A VAIIL E N GG A G 598
spoVD_pbp
TIGR02214 stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the ...
17-623
2.62e-80
stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the cell division protein FtsI, a penicillin binding protein. This subfamily is restricted to Bacillus subtilis and related Gram-positive species with known or suspected endospore formation capability. In these species, the functional equivalent of FtsI is desginated PBP-2B, a paralog of spoVD. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination]
Pssm-ID: 131269 [Multi-domain]
Cd Length: 636
Bit Score: 266.68
E-value: 2.62e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R LLALQAGIV A A F VV L A LRL WSM QV VHHED Y VKQ AE NNRE R K IPI V A P RG N ILDR H GN V L VD S RPTFSLMVNRED I QDEA 96
Cdd:TIGR02214 1 R SIHILISFT A L F LI L I LRL FYV QV FRGSF Y KEM AE DQWT R E IPI E A K RG R ILDR N GN E L AV S VSVDRVDLDPAT I RKNK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E TLRI ----- LA EEFGVAP E YARQQLRSPAARTRPVEVKSN I t DA D R A K v S V LDYEHPEFL V ELRPQ R K YP H G ELAC H I L 171
Cdd:TIGR02214 81 E PKQR eiane LA RVLEMDK E KVFKRITKKNSPFVSAKLGRK I - EK D K A E - K V RNLKLNGVS V SPDSK R Y YP N G DFLS H V L 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 172 G YVT evseaqlkrpefdycrp G D KV G QA GLE RF Y NRI L M G RD G Y R RIIV D RRGRFVREIET -- V P P IA G Q D I V T T L D LDL 249
Cdd:TIGR02214 159 G FTN ----------------- S D GR G LE GLE LY Y DKE L R G LP G V R VAEY D ANSLELPYAQH ay V K P VD G H D L V L T I D ENI 221
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 250 Q RVA E ERL - KAL KLNG ---- T I A VM D P R NGE M L ALASM P G YDPN LF aggis R ADYARY A N dkhkpl RNRA IQ D I Y P PGST 324
Cdd:TIGR02214 222 Q YII E REA d KAL RERK pkgv S I I VM N P K NGE I L GMSNR P T YDPN DP ----- R DKSPDT A R ------ RNRA VS D A Y E PGST 290
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 325 W KII MAV A G M RA G VL K PT D RLLCG G GIN VGG RHVR C M -- G S HG TPPLSTAIAK SC DGW F YR LG IK LG LDN L RT Y ASEL G A 402
Cdd:TIGR02214 291 F KII TSS A A M EE G IV K ES D KFYDD G SAT VGG KKIK C W kp G G HG SQTFPEVVQN SC NPG F IE LG MR LG AEK L NN Y ILAF G F 370
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 403 G EY TGIDLP N E FK G YIPSLELKAATVRR T M pnatpaqyrwtdadsvya S I GQA m VRP TP L Q MLRS V AGI A MR G EFHT PH F 482
Cdd:TIGR02214 371 G SK TGIDLP G E AA G ILVPKKKVGPVDLA T I ------------------ S F GQA - NTV TP I Q LMTA V NAV A NG G KLIQ PH I 431
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 483 LL E ARPT Q ERPGV - TF KDQ VKR IELPDDYWEAVIEGMWGA V NA G G ta SGS A LRD pet G FEMC GKTGTAQ V V s K LKASKL E 561
Cdd:TIGR02214 432 MK E ISDS Q NNAVD q TF EPE VKR QVVSKETTQKLRLALETV V SK G S -- GKN A FIE --- G YRVG GKTGTAQ K V - K PNGGYM E 505
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2035176090 562 ERDHSW FVGF G P REK P EI A AISL V EH -- G G -- FG AKAS AP NVRA VF EVW L R k KK G LPV Q VGAA EAP 623
Cdd:TIGR02214 506 GEYIVS FVGF A P ADD P AV A VLVV V DN pk G V qq FG GLVA AP VFGS VF NDI L N - YL G IKP Q MNQG EAP 570
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
264-604
5.30e-58
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 197.25
E-value: 5.30e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 264 G TIA V M DP RN GE M LA LASM P G YDPN L F A G gisradyaryandkhk PLRNRA IQDI Y P PGST W K IIM A V A GMRA GVLKP TD 343
Cdd:pfam00905 1 G SAV V L DP KT GE V LA MVGK P S YDPN G F I G ---------------- PLRNRA VTSR Y E PGST F K PFT A L A ALDN GVLKP DE 64
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 344 RLLCGG G INV GG RHVRCMGS -- H G TPP L ST A IAK S CDGWFYR L GI KLG L D N LR T Y ASEL G A G EY TGI D LP N E FK GY IPS l 421
Cdd:pfam00905 65 TIFDWP G KQQ GG KSIGDWNQ dq V G IGT L RQ A LEY S SNWYMQK L AQ KLG A D K LR S Y LKKF G Y G NK TGI G LP G E NA GY LTP - 143
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 422 elkaatvrrtmpnatpaqy R W TDADSVYAS IG QAM vrp TPLQ MLRSV A G IA MR G EFHT PH FLLEARPTQERP gvtfkd QV 501
Cdd:pfam00905 144 ------------------- Y W LEGATASFG IG LTI --- TPLQ QAQAY A A IA NG G KLVP PH LVKSIEDKVDPK ------ VL 195
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 502 KRIELPDDYW E A V IEGMWGA VN A G G ta SGSALRD P et G FEMC GKTGTAQV VSKLKASKLEERDHS WFVG FG P REK P EI A A 581
Cdd:pfam00905 196 NKLPISKSTA E K V KDMLRLV VN D G T -- GTGTAAV P -- G YKVA GKTGTAQV AGPKGGGYYDGAQIG WFVG YA P ADN P KY A F 271
330 340
....*....|....*....|....*
gi 2035176090 582 IS L VEHGG -- F G A K AS AP NVRAVF E 604
Cdd:pfam00905 272 AV L IDDPK ry Y G G K VA AP IFKDIL E 296
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
60-229
2.22e-49
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 170.20
E-value: 2.22e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 60 PI V APRG N I L DR H G N VL VDSR P TF SL MVNREDIQDE -- AE T LRI LA EEFGVAPEYARQQ L R ------ SPAARTR PV EV K S 131
Cdd:pfam03717 1 PI P APRG E I Y DR N G V VL ATNK P VY SL TITPSKLKKA da LK T ALK LA KLLSNYEDLDDED L T erflkm NSYKSYY PV VI K K 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 132 N ITDADR A KVSVLDY E H P EFLV E LR P Q R K YP H GELA C H I LGYV T E VS E AQ L KRPEFDYCRP GD K VG QA GLE RF Y NRI L M G 211
Cdd:pfam03717 81 N LSEEEV A RIEENLL E L P GVSI E TD P V R Y YP Y GELA A H L LGYV G E IT E EE L EKYLDKGYSR GD L VG KS GLE KQ Y ESV L R G 160
170
....*....|....*...
gi 2035176090 212 R DG Y R RII VD RR GR FV RE 229
Cdd:pfam03717 161 K DG V R QVE VD AL GR VI RE 178
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
17-608
6.21e-30
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 124.93
E-value: 6.21e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 17 R LLA L QAG I VA A F V V L AL R LWSM QV VHHEDY V KQAENNRE R KIPIVAP RG N I L DR H G NV L VD S R P TFSLMVNREDIQ D EA 96
Cdd:PRK15105 22 R FAL L CGC I LL A L V F L LG R VAWL QV INPDML V REGDMRSL R VQEVSTS RG M I T DR S G RP L AV S V P VKAIWADPKEVH D AG 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 97 E - TLRILAEEFGV A PEYARQ QL rsp A AR TRPVEVKSN I TD A DRAKVSVL DY EH ---- P EFLVELRPQ R K YP H GE LAC H IL 171
Cdd:PRK15105 102 G i SVDDRWKALAD A LNIPLD QL --- S AR INANPKGRF I YL A RQVNPDMA DY IK klkl P GIHLREESR R Y YP S GE VTA H LI 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 172 G y V T E V seaqlkrpefdycrpg D KV G QA G L E RFYNRI L M G RD G Y R RIIV DR R GR FVRE I ETVPPI A GQDIVTTL D LD LQ R 251
Cdd:PRK15105 179 G - F T N V ---------------- D SQ G IE G V E KSFDKW L T G QP G E R IVRK DR Y GR VIED I SSTDSQ A AHNLALSI D ER LQ A 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 252 - V AE E RLK A LKL N ---- G TIAVM D PRN GE M LA L A SM P G Y D PN LFA G GISR A dyaryandkhkp L RNRAI Q D IYP PGST W K 326
Cdd:PRK15105 242 l V YR E LNN A VAF N kaes G SAVLV D VNT GE V LA M A NS P S Y N PN NLS G TPKD A ------------ M RNRAI T D VFE PGST V K 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 327 IIMAVAGMRA GV L K p TDRL L CGGGINVG G RHVRCMGSHGTPP L STAIA KS CDGWFYR L GIKLGLDN L RTYA S EL G A G EY T 406
Cdd:PRK15105 310 PMVVMTALQR GV V K - ENSV L NTVPYRIN G HEIKDVARYSELT L TGVLQ KS SNVGVSK L ALAMPSSA L VDTY S RF G L G KA T 388
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 407 GID L PN E FK G YI P SLE lkaatvrrtmpnatpaqy RW T D ADSVYA S I G QA - MV rp TPLQ ML R SV A G I AMR G EF htphflle 485
Cdd:PRK15105 389 NLG L VG E RS G LY P QKQ ------------------ RW S D IERATF S F G YG l MV -- TPLQ LA R VY A T I GSY G IY -------- 440
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 486 a RP --- T QER P G V TF kdqv K R I e L P DDYWEA V IEG M WGAVNA GG TASGS A LR dpet G FEMCG KTGTA QV V S kl KASKLEE 562
Cdd:PRK15105 441 - RP lsi T KVD P P V PG ---- E R V - F P ESIVRT V VHM M ESVALP GG GGVKA A IK ---- G YRIAI KTGTA KK V G -- PDGRYIN 508
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2035176090 563 RDHSWFV G FG P REK P EI A AISLVE -- HG G -- F G AKA SAP NVR A VFEVW LR 608
Cdd:PRK15105 509 KYIAYTA G VA P ASQ P RF A LVVVIN dp QA G ky Y G GAV SAP VFG A IMGGV LR 558
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
238-643
2.02e-26
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 114.25
E-value: 2.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 238 G QD I V TTLD LD LQ RV AE ERL K AL ------- K L NGTIA V M DP RN GE M LA LA smpgydpnlfa GG isr A DY ARYAN dkhkpl 310
Cdd:COG0744 294 G LK I Y TTLD PK LQ KA AE KAV K NV lpegkpg G L QAALV V V DP KT GE V LA MV ----------- GG --- R DY GKSQF ------ 353
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 311 r NRA I Q DIYP PGST W K IIMAV A GMRA G v LK P TDRLLC ------ GGG I --- N VG GR hvrcmg SH G TPP L ST A I A K S CDGWF 381
Cdd:COG0744 354 - NRA T Q AKRQ PGST F K PFVYA A ALEQ G - YT P ATTVDD epvtfp GGG W spk N YD GR ------ YR G PVT L RE A L A N S LNTPA 425
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 382 Y RL GIKL GLD NLRTY A SE LG ageytgid LPNEFKGY i PSL E L KAAT V rrtmpnatpaqyrwtdadsvyasigqamvrp T P 461
Cdd:COG0744 426 V RL AQEV GLD KVVDT A RR LG -------- ITSPLDPN - PSL A L GTSE V ------------------------------- S P 465
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 462 L Q M LRSV A GI A MR G EFHT PH FLLEARPTQERPGVTF K DQVKRI e LPDDYWEAVIEGMWGA V N a G GT ASGSA L rdpe T G FE 541
Cdd:COG0744 466 L E M ASAY A TF A NG G VYVE PH AITKVTDADGKVLYEA K PKCEQV - ISPEVAYLMTDMLQDV V T - S GT GRAAR L ---- P G RP 539
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 542 MC GKTGT AQ vvsklkaskl EE RD h S WFVG FG prek P EIAAISL V ------- EHGGF G AKAS AP NV R AVF E VW L rkk K GLP 614
Cdd:COG0744 540 VA GKTGT TN ---------- DN RD - A WFVG YT ---- P QLVTAVW V gnddnsp MGYVT G GSLP AP IW R DFM E AA L --- E GLP 601
410 420 430
....*....|....*....|....*....|.
gi 2035176090 615 V Q vg AAEA P GP V R -- PAAR PTP RPQT P AQ T P 643
Cdd:COG0744 602 V E -- DFPK P SG V V ri DEPS PTP SGTE P TE T S 630
PBP_1a_fam
TIGR02074 penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
230-574
1.48e-11
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain]
Cd Length: 531
Bit Score: 67.28
E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 230 I ETVPPIA G QD ------- I V TTLDLD L Q RV AE ER L K ---------- ALK L NGTIAVM DP RN G EML AL ASMPG Y DPNL F ag 292
Cdd:TIGR02074 206 I QELEEEY G EE lytgglk I Y TTLDLD A Q KA AE KV L N tglrvagrrd GDD L QAALVAI DP DT G AVR AL VGGRD Y GKSQ F -- 283
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 293 gisradyaryandkhkplr NRA I Q DIYP PGST W K IIMAV A GMRA G v L K P TDRL ------ LC G G G I ---- N V GG RH vrcmg 362
Cdd:TIGR02074 284 ------------------- NRA T Q AKRQ PGST F K PFVYA A ALEK G - L T P ATIV ndepit YN G N G P wspk N Y GG GY ----- 338
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 363 s H G TPP L ST A I A K S CDGWFY RL GIKL GLD NLRTY A SEL gageyt GI DL P nef KGYIP SL E L KAAT V rrtmpnatpaqyrw 442
Cdd:TIGR02074 339 - R G NVT L RQ A L A Q S RNIPAV RL LQEV GLD KVVAL A KRF ------ GI TS P --- LDPVL SL A L GTVE V -------------- 394
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 443 tdadsvyasigqamvrp T PL Q M LRSV A GI A MR G EFHT PH FL lea R PTQE R P G VTFKD - QV K RIELPDDYWEAVIEG M WGA 521
Cdd:TIGR02074 395 ----------------- S PL E M ASAY A VF A NG G KYVE PH GI --- R KIVD R D G KVIYE n KP K TTQVISPATAYIMTD M LKG 454
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2035176090 522 V NAG GT ASGSA L rdpe T G FEMC GKTGT A Q vvsklkaskl EE RD h S WFVG FG P R 574
Cdd:TIGR02074 455 V VES GT GRSAR L ---- P G RPVA GKTGT T Q ---------- NW RD - A WFVG YT P Y 492
MrcA
COG5009 Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
43-617
6.31e-05
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain]
Cd Length: 785
Bit Score: 46.31
E-value: 6.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 43 HHED Y VK QAE NNRERKI P IV A prgnil DR HG NVLVDSR P T F SL MV N RE diqdeaetlri L A E EF G VAPE Y ---------- 112
Cdd:COG5009 230 LELG Y IT QAE YEAAKAE P LT A ------ RY HG ASAEVDA P Y F AE MV R RE ----------- L V E RY G EDAL Y tgglkvyttl 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 113 - A R Q Q L rsp AA RT rpv EVKSNITDA DR AK ----- VSV LD YEHPEFLVE L RPQRKY ph G E L ach ILGY V T EV SEAQLKR pe 186
Cdd:COG5009 293 d P R L Q E --- AA EK --- ALRDGLLAY DR RH gyrgp EAH LD LAEEDWDEA L AEVPDV -- G D L --- RPAV V L EV DDKSARV -- 359
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 187 fd YC R P G DK -- VGQA GL erfynrilmg RDGYRR I IVD RRG R fvreietv P P IAGQ D IVTTL D LDLQ R VAEERLKA L ---- 260
Cdd:COG5009 360 -- GL R D G ET gt LPLE GL ---------- KWARPY I NDN RRG P -------- A P KSAS D VLKPG D VIRV R PVADGGWR L rqip 419
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 261 KLN G TIAVM DP RN G EM LAL A smpgydpnlfa GG IS radyar YAND K H kplr NRA I Q DIYP PGS TW K - IIM A v A GMRA G v L 339
Cdd:COG5009 420 EVQ G ALVAL DP HT G AV LAL V ----------- GG FD ------ FEQS K F ---- NRA T Q AKRQ PGS SF K p FVY A - A ALDN G - Y 476
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 340 K P TDRLL --------- C GGG I ---- N VG G R hvrcmg SH G TPP L ST A IA KS cdgwfy RL GIKL G L D NLRT YA SEL G AGE yt 406
Cdd:COG5009 477 T P ATIIN dapivfddg G GGG V wrpk N YS G K ------ FY G PTT L RE A LE KS rnlvtv RL LQDV G I D YVID YA ERF G IYS -- 548
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 407 gi D LP NE fkgyi P SL E L KAAT V rrtmpnatpaqyrwtdadsvyasigqamvrp TPL Q M L R SV A GI A MR G EFHT P HF ---- 482
Cdd:COG5009 549 -- K LP PN ----- L SL A L GSGE V ------------------------------- TPL E M A R AY A VF A NG G YRVE P YL idri 590
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 483 ------- LLE A R P TQERPGVTFKDQVKRIELPD D YW E A VI EG --------- MW G A V N a G GT ASG - S AL rdpet G FEMC GK 545
Cdd:COG5009 591 edrngkv IYR A D P ARACEDCDAAEWDGAEPRLP D PA E Q VI DP rtayqmtsm LR G V V Q - R GT GRR a R AL ----- G RDIA GK 664
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176090 546 TGT AQ vvsklkaskl EER D h S WFVGF G prek P EIA A ISL V -------- EH G GF G AK A SA P NVRAVFEVW L RK K KGL P VQ V 617
Cdd:COG5009 665 TGT TN ---------- DSK D - A WFVGF T ---- P DLV A GVW V gfddprsl GR G ET G GR A AL P IWIDFMKAA L KD K PEK P FP V 729
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
