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Conserved domains on  [gi|2035176764|ref|WP_211422334|]
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protein translocase subunit SecF [Chloracidobacterium aggregatum]

Protein Classification

protein translocase subunit SecF( domain architecture ID 11417410)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952
TCDB:  2.A.6.4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 4-386 3.47e-123

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 358.98  E-value: 3.47e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   4 LFRNPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFNLGVDFAGGTKMTVRFVSPPDENRIREALRNGGYTPdkVVIQRT 83
Cdd:COG0341     3 FPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGD--ASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  84 GkqlsqsDRNEVFINTPQTEADVDGDKRKITEALQKYYGApadpdkldinlvgasslatrlteldvldlkktlppgeaer 163
Cdd:COG0341    81 G------SDNDVLIRTPPLDGESAEEVEKVRAALKEAFGD---------------------------------------- 114

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 164 eyrrfadhviqtrdaaggtladlkaipltgfdpkmaealeraatvgaFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGML 243
Cdd:COG0341   115 -----------------------------------------------VEIVRVEFVGPTVGKELTRKALLALLVALIGIL 147

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 244 LFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTN 323
Cdd:COG0341   148 IYIAFRFEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIIN 227

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2035176764 324 DAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:COG0341   228 LSINQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGK 290
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 4-386 3.47e-123

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 358.98  E-value: 3.47e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   4 LFRNPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFNLGVDFAGGTKMTVRFVSPPDENRIREALRNGGYTPdkVVIQRT 83
Cdd:COG0341     3 FPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGD--ASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  84 GkqlsqsDRNEVFINTPQTEADVDGDKRKITEALQKYYGApadpdkldinlvgasslatrlteldvldlkktlppgeaer 163
Cdd:COG0341    81 G------SDNDVLIRTPPLDGESAEEVEKVRAALKEAFGD---------------------------------------- 114

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 164 eyrrfadhviqtrdaaggtladlkaipltgfdpkmaealeraatvgaFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGML 243
Cdd:COG0341   115 -----------------------------------------------VEIVRVEFVGPTVGKELTRKALLALLVALIGIL 147

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 244 LFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTN 323
Cdd:COG0341   148 IYIAFRFEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIIN 227

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2035176764 324 DAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:COG0341   228 LSINQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGK 290
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 7-386 4.76e-99

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 311.78  E-value: 4.76e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   7 NPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFNLGVDFAGGTKMTVRFVSPPDENRIREALRNGGYTPDKVVIQrtgkq 86
Cdd:PRK13024  446 FDRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTF----- 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  87 lsQSDRNEVFINTPQTEadvDGDKRKITEALQKYYGApadpdkldinlvgasslatrlteldvldLKKTLPPGeaereyr 166
Cdd:PRK13024  521 --GSDNNQVLVRTYGIL---SDDEEADTEIVAKLKNA----------------------------LKNDKGGT------- 560

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 167 rfadhviqtrdaaggtladlkaipltgfdpkmaealeraatvgafnVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFI 246
Cdd:PRK13024  561 ----------------------------------------------IPSSETVGPTVGKELARNAIIAVLIALIGILLYI 594

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 247 AFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAI 326
Cdd:PRK13024  595 LIRFEWTFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSI 674

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 327 NQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:PRK13024  675 NQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEK 734
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 205-386 4.56e-71

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 222.10  E-value: 4.56e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 205 AATVGAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTF 284
Cdd:pfam02355   7 KNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIEVDLAT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 285 IAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLV 364
Cdd:pfam02355  87 VAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLV 166

                         170       180
                  ....*....|....*....|..
gi 2035176764 365 GILFGTYSSIAIASPILLWWKR 386
Cdd:pfam02355 167 GVIVGTYSSIFIASPILLDLGE 188
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 209-377 6.66e-70

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 220.99  E-value: 6.66e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 209 GAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAM 288
Cdd:TIGR00966  78 PDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAAL 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 289 LTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILF 368
Cdd:TIGR00966 158 LTIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIV 237


                  ....*....
gi 2035176764 369 GTYSSIAIA 377
Cdd:TIGR00966 238 GTYSSIFIA 246
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 197-384 6.41e-10

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 61.33  E-value: 6.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  197 KMAEALERAATVG-AFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEwVYGVAAVIAVVHDVLVTLGLFSL 275
Cdd:NF037998   412 RTIEALINQTTSGfTFKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYR-LLGLFAIIIALTSISLTLYSPTW 490

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  276 FQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRdDLAVVTNDAINQTLSrtVITSGLTLLSVLALVLF--GGE 353
Cdd:NF037998   491 FGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKR-SIEESFKIANKETIG--IIVDALVVLLIPNLSLFwiGSN 567

                          170       180       190
                   ....*....|....*....|....*....|.
gi 2035176764  354 VLKSFSLALLVGILFGTYSSIAIAspILLWW 384
Cdd:NF037998   568 SIKSFATILLVGVIISLVLVIIVA--RLMIW 596
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 233-319 8.79e-07

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 51.32  E-value: 8.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  233 IVTIVACIgmLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAE 312
Cdd:NF037998   963 FAIILLAL--IVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSLISS 1040


                   ....*..
gi 2035176764  313 RRRDDLA 319
Cdd:NF037998  1041 KNKKELE 1047
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 4-386 3.47e-123

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 358.98  E-value: 3.47e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   4 LFRNPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFNLGVDFAGGTKMTVRFVSPPDENRIREALRNGGYTPdkVVIQRT 83
Cdd:COG0341     3 FPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGD--ASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  84 GkqlsqsDRNEVFINTPQTEADVDGDKRKITEALQKYYGApadpdkldinlvgasslatrlteldvldlkktlppgeaer 163
Cdd:COG0341    81 G------SDNDVLIRTPPLDGESAEEVEKVRAALKEAFGD---------------------------------------- 114

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 164 eyrrfadhviqtrdaaggtladlkaipltgfdpkmaealeraatvgaFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGML 243
Cdd:COG0341   115 -----------------------------------------------VEIVRVEFVGPTVGKELTRKALLALLVALIGIL 147

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 244 LFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTN 323
Cdd:COG0341   148 IYIAFRFEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIIN 227

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2035176764 324 DAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:COG0341   228 LSINQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGK 290
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 7-386 4.76e-99

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 311.78  E-value: 4.76e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   7 NPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFNLGVDFAGGTKMTVRFVSPPDENRIREALRNGGYTPDKVVIQrtgkq 86
Cdd:PRK13024  446 FDRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTF----- 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  87 lsQSDRNEVFINTPQTEadvDGDKRKITEALQKYYGApadpdkldinlvgasslatrlteldvldLKKTLPPGeaereyr 166
Cdd:PRK13024  521 --GSDNNQVLVRTYGIL---SDDEEADTEIVAKLKNA----------------------------LKNDKGGT------- 560

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 167 rfadhviqtrdaaggtladlkaipltgfdpkmaealeraatvgafnVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFI 246
Cdd:PRK13024  561 ----------------------------------------------IPSSETVGPTVGKELARNAIIAVLIALIGILLYI 594

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 247 AFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAI 326
Cdd:PRK13024  595 LIRFEWTFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSI 674

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 327 NQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:PRK13024  675 NQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEK 734
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 205-386 4.56e-71

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 222.10  E-value: 4.56e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 205 AATVGAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTF 284
Cdd:pfam02355   7 KNVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLFGIEVDLAT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 285 IAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLV 364
Cdd:pfam02355  87 VAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLV 166

                         170       180
                  ....*....|....*....|..
gi 2035176764 365 GILFGTYSSIAIASPILLWWKR 386
Cdd:pfam02355 167 GVIVGTYSSIFIASPILLDLGE 188
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 209-377 6.66e-70

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 220.99  E-value: 6.66e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 209 GAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAM 288
Cdd:TIGR00966  78 PDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAAL 157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 289 LTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILF 368
Cdd:TIGR00966 158 LTIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIV 237


                  ....*....
gi 2035176764 369 GTYSSIAIA 377
Cdd:TIGR00966 238 GTYSSIFIA 246
PRK14726 PRK14726
protein translocase subunit SecDF;
199-386 6.32e-57

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 200.72  E-value: 6.32e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 199 AEALERAATVGAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQW 278
Cdd:PRK14726  642 AVTLVRGELEDDYDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIWIRFEWQFAVGAIIATLHDVILTLGLFVLTGI 721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 279 EISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSF 358
Cdd:PRK14726  722 EFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILIDASINQTLSRTVLTSATTLLALLALYLFGGEVIRSF 801

                         170       180
                  ....*....|....*....|....*...
gi 2035176764 359 SLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:PRK14726  802 TFAMLFGVAVGTFSSIYIAAPVLIVFKL 829
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 186-374 5.59e-54

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 178.22  E-value: 5.59e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 186 LKAIPLTGFDPKMAEALERAATVGAFNVVSAEIVG---PQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAV 262
Cdd:TIGR00916   1 LDEEGAKIFADFAANIGKPAIVLDNAKVISAPVVGtvgPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 263 VHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLL 342
Cdd:TIGR00916  81 VHDVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDRIREELRKYKGRTFREAINLGINQTLSRIIDTNVTTLL 160

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2035176764 343 SVLALVLFGGEVLKSFSLALLVGILFGTYSSI 374
Cdd:TIGR00916 161 AVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 196-378 1.89e-49

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 169.65  E-value: 1.89e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 196 PKMAEALERAATvgAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSL 275
Cdd:PRK13021   95 VDIQQALAPLGT--EVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHDVIFVLAFFAL 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 276 FQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVL 355
Cdd:PRK13021  173 TQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIVATFSRTMVTSGTTLMTVGALWIMGGGPL 252

                         170       180
                  ....*....|....*....|...
gi 2035176764 356 KSFSLALLVGILFGTYSSIAIAS 378
Cdd:PRK13021  253 EGFSIAMFIGILTGTFSSISVGT 275
PRK13023 PRK13023
protein translocase subunit SecDF;
217-382 2.20e-37

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 144.76  E-value: 2.20e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 217 EIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSM 296
Cdd:PRK13023  566 DVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSL 645

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 297 NDTIVIFDRIREQLAERRRDDLAVVTNDAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAI 376
Cdd:PRK13023  646 NDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFI 725


                  ....*.
gi 2035176764 377 ASPILL 382
Cdd:PRK13023  726 AAPLLV 731
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 1-386 4.81e-37

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 144.23  E-value: 4.81e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764    1 MMELFRNPNYDFLGKAKYFIGFSVIVLVAGCISMVVRGFN--LGVDFAGGTKMTvrfvsppdenrirealrnggytpdkv 78
Cdd:PRK12911  1072 MMNKFIGIKHDFLKECKRLWVVSGSVLVLGCVALGFGAWNsvLGMDFKGGYALT-------------------------- 1125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764   79 viqrtgkqLSQSDrnevfintpQTEADVDGDKRKITEALQKyygapadpdkldinlVGASSLATRLTELDVLDLKKTLPP 158
Cdd:PRK12911  1126 --------LDPSD---------VCEYDVEQMRSKLRKKFQQ---------------IGLSSRDFRIRTFDSSEKIKIYFS 1173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  159 GEA-------EREYRRFADHVIQTrdaAGGTLADlkaiplTGFDPKmAEALEraATVGAFNVVSAeivgpQVGKDLRNRA 231
Cdd:PRK12911  1174 QNAldrveaiEGAGSEQSDHHLAL---VLGVLSD------TGSDTS-SEVFD--ATQNFWFKVSG-----QLSNKMRTQA 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  232 IIVTIVACIGMLLFIAFRFEWVYGVAAVIAVVHDVLVTLGL-----FSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRI 306
Cdd:PRK12911  1237 VIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLATCAVlvalhFFLQKIQIDLQAIGALMTVLGYSLNNTLIIFDRI 1316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  307 REQLAERRRDDLAVVTNDAINQTLSRTVITSGlTLLSVLALVLF-GGEVLKSFSLALLVGILFGTYSSIAIASPILLWWK 385
Cdd:PRK12911  1317 REDRQEKLFTPMPILINDALQKTLGRTVMTTA-TTLSVLLILLFvGGGSIFNFAFIMTIGILLGTLSSLYIAPPLLLFMV 1395


                   .
gi 2035176764  386 R 386
Cdd:PRK12911  1396 R 1396
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 198-381 2.61e-18

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 86.19  E-value: 2.61e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 198 MAEALERAATVGAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEWvYGVAAVIAVVHDVLVTLGLFSLFQ 277
Cdd:TIGR01129 217 LALVLRSGALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRL-FGLIAAIALVINIVLILAILSAFG 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 278 WEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVvtnDAINQTLSRTVITSGLT-LLSVLALVLFGGEVLK 356
Cdd:TIGR01129 296 ATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAI---EAGFERAFSTIFDANITtLIAALILYVFGTGPVK 372

                         170       180
                  ....*....|....*....|....*
gi 2035176764 357 SFSLALLVGILFGTYSSIAIASPIL 381
Cdd:TIGR01129 373 GFAVTLAIGIIASLFTALVFTRLLL 397
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 211-384 2.25e-15

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 78.35  E-value: 2.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 211 FNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFrfewVYGVA---AVIAVVHDVLVTLGLFSLFQWEISLTFIAA 287
Cdd:PRK13024  248 LKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLV----YYGLPgliANIALLLYIFLTLGALSSLGAVLTLPGIAG 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 288 MLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVvtNDAINQTLSrTVITSGLT-LLSVLALVLFGGEVLKSFSLALLVGI 366
Cdd:PRK13024  324 LVLGIGMAVDANVLIFERIKEELRKGKSLKKAF--KKGFKNAFS-TILDSNITtLIAAAILFFFGTGPVKGFATTLIIGI 400

                         170
                  ....*....|....*...
gi 2035176764 367 LFGTYSSIAIASPILLWW 384
Cdd:PRK13024  401 LASLFTAVFLTRLLLELL 418
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 155-368 8.29e-14

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 71.50  E-value: 8.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 155 TLPPGEAEREYRRFADhVIQTRDAAGGTLADLKAIPLTGFDPKMAEALERAATVGAFNVVSAE-IVGPQVGKDLRNRAII 233
Cdd:PRK08578   60 DASPDELESALSGEPG-VDVRKGSGNGYIITFGSGDDTDVDKLADAVKEFFNVDSISELNYSEkQIGPTFGSQFQEQALK 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 234 VTIVACIGM--LLFIAFRfEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIReqla 311
Cdd:PRK08578  139 AVGFAFIGMavVVFLIFR-TPVPSLAVILSAFSDIIIALALMNLFGIELSLATVAALLMLIGYSVDSDILLTTRVL---- 213

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2035176764 312 eRRRDDLavvtNDAINQTLsRTVITSGLTLLS---VLALV--LFGGEVLKSFSLALLVGILF 368
Cdd:PRK08578  214 -KRRGTF----DESIKRAM-RTGITMTLTTIAamaVLYIVstIPQAEVLANIAAVLIFGLLA 269
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 211-384 1.21e-13

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 72.07  E-value: 1.21e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 211 FNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFeWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLT 290
Cdd:COG0342   253 LEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYY-RLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIIL 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 291 LVGYSMNDTIVIFDRIREQLAERRRddlavvTNDAINQTLSR---TVITSGLT-LLSVLALVLFGGEVLKSFSLALLVGI 366
Cdd:COG0342   332 TIGMAVDANVLIFERIREELRAGRS------LRAAIEAGFKRafsTILDANVTtLIAAVVLFVLGTGPVKGFAVTLILGI 405

                         170
                  ....*....|....*...
gi 2035176764 367 LFGTYSSIAIASPILLWW 384
Cdd:COG0342   406 LISMFTAVPVTRPLLNLL 423
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 211-387 2.26e-12

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 68.33  E-value: 2.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 211 FNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAF--RfewVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAM 288
Cdd:PRK05812  279 LEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILyyR---LFGLIANIALVANLVLILAVLSLLGATLTLPGIAGI 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 289 LTLVGYSMNDTIVIFDRIREQLAERRRDDLAVVT--NDAinqtlSRTVITSGLT-LLSVLALVLFG-GEVlKSFSLALLV 364
Cdd:PRK05812  356 VLTIGMAVDANVLIFERIREELREGRSLRSAIEAgfKRA-----FSTILDSNITtLIAAIILYALGtGPV-KGFAVTLGI 429

                         170       180
                  ....*....|....*....|....
gi 2035176764 365 GILFGTYSSIAIASPIL-LWWKRY 387
Cdd:PRK05812  430 GILTSMFTAITVTRALVnLLYGRR 453
PRK14726 PRK14726
protein translocase subunit SecDF;
201-367 1.63e-11

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 66.28  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 201 ALERAATVGA-FNVVSAEIVGPQVGKDLRNRAIIVTIVACIGM--LLFIAFRFewvYGVAAVIAVVHDVLVTLGLFSLFQ 277
Cdd:PRK14726  343 VLLRAGALPAtLTVVEERTVGPGLGADSIAAGLVAGLIAAILVaaLMIGFYGF---LGVIAVIALIVNVVLIIAVLSLLG 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 278 WEISLTFIAAMLTLVGYSMNDTIVIFDRIREQlaERRRDDLAVVTNDAINQTLsRTVITSGLTLLsVLALVLF--GGEVL 355
Cdd:PRK14726  420 ATLTLPGIAGIVLTIGMAVDSNVLIYERIREE--EKTGHSLIQALDRGFSRAL-ATIVDANVTIL-IAAVILFflGSGAV 495

                         170
                  ....*....|..
gi 2035176764 356 KSFSLALLVGIL 367
Cdd:PRK14726  496 RGFAVTLAVGIL 507
PRK13023 PRK13023
protein translocase subunit SecDF;
198-386 1.04e-10

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 63.87  E-value: 1.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 198 MAEALERAATVGAFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEwVYGVAAVIAVVHDVLVTLGLFSLFQ 277
Cdd:PRK13023  247 MAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYG-ILGVIALVALVVNIIILTAVLSLIG 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 278 WEISLTFIAAMLTLVGYSMNDTIVIFDRIREQlaerRRDDLAVV--TNDAINQTLSRTVITSGLTLLSVLALVLFGGEVL 355
Cdd:PRK13023  326 ASISLASIAGLVLTIGLAVDAHILIYERVRED----RRKGYSVVqaMESGFYRALSTIVDANLTTLIAALVLFLLGSGTV 401

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2035176764 356 KSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:PRK13023  402 HGFALTVAIGIGTTLFTTLTFTRLLIAQWVR 432
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 197-384 6.41e-10

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 61.33  E-value: 6.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  197 KMAEALERAATVG-AFNVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRFEwVYGVAAVIAVVHDVLVTLGLFSL 275
Cdd:NF037998   412 RTIEALINQTTSGfTFKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYR-LLGLFAIIIALTSISLTLYSPTW 490

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  276 FQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRdDLAVVTNDAINQTLSrtVITSGLTLLSVLALVLF--GGE 353
Cdd:NF037998   491 FGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKR-SIEESFKIANKETIG--IIVDALVVLLIPNLSLFwiGSN 567

                          170       180       190
                   ....*....|....*....|....*....|.
gi 2035176764  354 VLKSFSLALLVGILFGTYSSIAIAspILLWW 384
Cdd:NF037998   568 SIKSFATILLVGVIISLVLVIIVA--RLMIW 596
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 197-384 2.26e-08

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 56.41  E-value: 2.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  197 KMAEALERAATVGAFNVVSAEIVGPQVGKDLRNRAIIVtivACIGMLLFIA-----FRFEwvyGVAAVIAVVHDVLVTLG 271
Cdd:PRK12911   877 RLATDLKSGAMSFVPEVLSEEVISPELGKSQRTQGIIS---VCLGLAVLIVlmsvyYRFG---GVIASGAVLLNLLLIWA 950

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  272 LFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAERRRDDLAVvtnDAINQTLSRTVITSGLT--LLSVLALVL 349
Cdd:PRK12911   951 ALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESV---EAGYKKAFSAIFDSNLTtiLASALLLML 1027

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 2035176764  350 FGGEVlKSFSLALLVGILFGTYSSIAIASPILLWW 384
Cdd:PRK12911  1028 DTGPI-KGFALTLIIGIFSSMFTALFMTKFFFMIW 1061
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
230-391 4.39e-08

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 55.25  E-value: 4.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 230 RAIIVTIVAcIGMLLFIAFRfEWVYGVAAVIAVVHDVLVTLGLFSLFqwEISLTFIAAMLT--LVGYSMNDTIVIFDRIR 307
Cdd:COG1033   609 RSLLLALLL-IFLLLLLAFR-SLRLGLISLIPNLLPILLTFGLMGLL--GIPLNIATAVVAsiALGIGVDYTIHFLSRYR 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 308 EQLAERRRDDLAVVTndAINQTlSRTVITSGLTL-LSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKR 386
Cdd:COG1033   685 EERRKGGDLEEAIRR--ALRTT-GKAILFTSLTLaAGFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDP 761


                  ....*
gi 2035176764 387 YLAQR 391
Cdd:COG1033   762 RIAKK 766
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
231-392 1.35e-07

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 53.71  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 231 AIIVTIVacigmLLFIAFRfEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQL 310
Cdd:COG1033   227 ALLLILL-----LLFLFFR-SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREER 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 311 AERRRDDLAVVTndAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFGTYSSIAIASPILLWWKRYLAQ 390
Cdd:COG1033   301 RKGLDKREALRE--ALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPK 378


                  ..
gi 2035176764 391 RQ 392
Cdd:COG1033   379 TR 380
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 207-381 3.57e-07

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 52.53  E-value: 3.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 207 TVGAFNVVSAEIvGPQVGKDLRNRAIIVTIVacIGMLLFIAFRfEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIA 286
Cdd:TIGR00921 550 GVTGLPVAFAEM-HELVNEGMRRMTIAGAIL--VLMILLAVFR-NPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMAT 625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 287 AMLTLVGYSMNDTIVIFDRIREQlaerrRDDLAVVtnDAINQTLSRT---VITSGLTL-LSVLALVLFGGEVLKSFSLAL 362
Cdd:TIGR00921 626 TISIILGLGMDYSIHLAERYFEE-----RKEHGPK--EAITHTMERTgpgILFSGLTTaGGFLSLLLSHFPIMRNFGLVQ 698

                         170
                  ....*....|....*....
gi 2035176764 363 LVGILFGTYSSIAIASPIL 381
Cdd:TIGR00921 699 GIGVLSSLTAALVVFPALL 717
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 233-319 8.79e-07

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 51.32  E-value: 8.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764  233 IVTIVACIgmLLFIAFRFEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIVIFDRIREQLAE 312
Cdd:NF037998   963 FAIILLAL--IVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKAKSLISS 1040


                   ....*..
gi 2035176764  313 RRRDDLA 319
Cdd:NF037998  1041 KNKKELE 1047
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
 199-386 3.56e-06

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 49.38  E-value: 3.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 199 AEALERAATVGAFNVVSAEIVGP---------QVGKDLRnRAIIVTIVACIGMLLFiafrfewVYG--VAA---VIAVVH 264
Cdd:COG2409   134 VDALRDAVAAAPAPGLTVYVTGPaalaadlneAFEEDLG-RAELITLPVALVVLLL-------VFRslVAAllpLLTAGL 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 265 DVLVTLGLFSLFQWEISL-TFIAAMLTLVG------YSmndtIVIFDRIREQLAERRRDDLAVVTndAInQTLSRTVITS 337
Cdd:COG2409   206 AVGVALGLLALLAAFTDVsSFAPNLLTMLGlgvgidYA----LFLVSRYREELRAGEDREEAVAR--AV-ATAGRAVLFS 278

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2035176764 338 GLT-LLSVLALVLFGGEVLKSFSLALLVGILFGTYSSI-------AIASPILLWWKR 386
Cdd:COG2409   279 GLTvAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALtllpallALLGRRVFWPRR 335
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 223-386 4.65e-06

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 49.07  E-value: 4.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 223 VGKDLrnraIIVTIVACIGM--LLFIAFRfEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTI 300
Cdd:TIGR00921 191 FGKDM----GTTMAISGILVvlVLLLDFK-RWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGI 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 301 VIFDRIREQLAERRRDDLAVVTndAINQTLSRTVITSGLTLLSVLALVLFGGEVLKSFSLALLVGILFgTYSSIAIASPI 380
Cdd:TIGR00921 266 QTLNRYEEERDIGRAKGEAIVT--AVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLIT-AYLLTLLVLPA 342

                         170
                  ....*....|
gi 2035176764 381 LL----WWKR 386
Cdd:TIGR00921 343 LLqsidIGRE 352
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 33-58 7.09e-06

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 42.27  E-value: 7.09e-06
                          10        20
                  ....*....|....*....|....*.
gi 2035176764  33 SMVVRGFNLGVDFAGGTKMTVRFVSP 58
Cdd:pfam07549   1 SLFTRGLNLGLDFTGGTVIELQFDQP 26
COG4258 COG4258
Predicted exporter [General function prediction only];
227-368 7.63e-05

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 45.23  E-value: 7.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 227 LRNRAIIVTIVACIGMLLFIAFR-FEWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLTLVGYSMNDTIvIFDR 305
Cdd:COG4258   637 YRNDALWLLLLALLLILLLLLLRlRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL-FFTE 715

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2035176764 306 IREQLAERRRDDLAVvtndainqTLSrtVITsglTLLSVLALVLFGGEVLKSFSLALLVGILF 368
Cdd:COG4258   716 GLLDKGELARTLLSI--------LLA--ALT---TLLGFGLLAFSSTPALRSFGLTVLLGILL 765
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
 172-368 1.44e-04

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 43.99  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 172 VIQTRDAAGGTLADLKAIPLTG-FDPKMAEALE--RAATVGAFNVVSAEIVG-PQVGKDLRNRA------IIVTIVACIG 241
Cdd:COG2409   452 PPTRPEGTDGDAARLQVVPDGDpDSPEAIDLVDrlRDAAAPALEGAEVLVGGtTAVNIDISDALaddlplVIPVVLGLIF 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 242 MLLFIAFRFEWVyGVAAVIAVVHDVLVTLGLFSL-FQWE-----------ISLTFIAAMLTLVGYSMNDTIVIFDRIREQ 309
Cdd:COG2409   532 LLLLLLFRSVVA-PLKAVLTNLLSLGAALGVLVLvFQHGwlllgftpgplDSFVPLLLFVILFGLGMDYEVFLVSRIREE 610

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2035176764 310 LAERRRDDLAVVTndainqTLSRT--VITS-GLTLLSV-LALVLFGGEVLKSFSLALLVGILF 368
Cdd:COG2409   611 YDRGGGTREAVIR------GLARTgrVITSaALIMAAVfAAFATSPLVFLKQIGFGLAVGVLL 667
secD PRK12933
protein translocase subunit SecD;
240-384 3.02e-04

protein translocase subunit SecD;


Pssm-ID: 183831 [Multi-domain]  Cd Length: 604  Bit Score: 43.14  E-value: 3.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 240 IGM---LLFIAF---RFEWVygvaAVIAVVHDVLVTLGLFSLFQWEI-SLTFIAAMLTLVGYSMNDTIVIFDRIREQLAE 312
Cdd:PRK12933  448 LGMgitLLFMALwyrRLGWV----ANVALIANMVCLFGLLALIPGAVlTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKE 523

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2035176764 313 RRRDDLAVVTN-DAINQTLSRTVITSGLTllsvlALVLF--GGEVLKSFSLALLVGILFGTYSSIaIASPILLWW 384
Cdd:PRK12933  524 GRSFAQAIDTGfDSAFSTIFDANFTTMIT-----AVVLYsiGNGPIQGFALTLGLGLLTSMFTGI-FASRALINL 592
secD PRK08343
preprotein translocase subunit SecD; Reviewed
 212-369 7.42e-04

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 236245 [Multi-domain]  Cd Length: 417  Bit Score: 41.40  E-value: 7.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 212 NVVSAEIVGPQVGKDLRNRAIIVTIVACIGMLLFIAFRF-EWVYGVAAVIAVVHDVLVTLGLFSLFQWEISLTFIAAMLT 290
Cdd:PRK08343  244 DIEGSGSVSPSLGEQFKKGSLIAGLLALLAVALVVFLRYrEPRIALPMVITSLSEVIIILGFAALIGWQLDLASIAGIIA 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2035176764 291 LVGYSMNDTIVIFDRI--REQLAERRRddlavvtndainqTLSR-----TVI-TSGLTL---LSVLALVLFGGevLKSFS 359
Cdd:PRK08343  324 VIGTGVDDLIIITDEVlhEGKVPSRKV-------------FLSRikrafFIIfAAAATTiaaMSPLAVMGLGD--LKGFA 388

                         170
                  ....*....|
gi 2035176764 360 LALLVGILFG 369
Cdd:PRK08343  389 ITTILGVLIG 398
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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