NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2048202307|ref|WP_214798779|]
View 

InlB B-repeat-containing protein [Exiguobacterium sp. s50]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
704-877 2.39e-08

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 58.09  E-value: 2.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  704 VTNLKVVSKGGEATLTWNGTVGTTFYFLDVSNDSDFASFTRYKVNERNYNLYLAPKGIHYIRVKPILTLENQDWEGSSST 783
Cdd:COG3401    147 LYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSV 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  784 VFRDSLLKKIDGIKISDVTSTSVKLSWNRQNYNH---FYVYRAED-NGIFKQVATVNTEAWTDTRLDHRKDYQYKIVGHl 859
Cdd:COG3401    227 TTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDatgYRVYRSNSgDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV- 305
                          170
                   ....*....|....*...
gi 2048202307  860 kldDTGGLLSEVSDVVSV 877
Cdd:COG3401    306 ---DAAGNESAPSNVVSV 320
Flg_new pfam09479
Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core ...
661-696 3.24e-04

Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core region of about 43 residues which occurs in more than 400 mostly secreted or cell surface-located proteins from over 300 eubacterial and few archaeal species. These proteins contain between one and 34 copies of the domain that often occur in tandem arrays with up to more than 20 copies.


:

Pssm-ID: 462813 [Multi-domain]  Cd Length: 65  Bit Score: 39.92  E-value: 3.24e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2048202307  661 EPTKSNHFFIGWYKDQAFTEKIDLNQDVT--ESMDLYA 696
Cdd:pfam09479   27 DPTKEGYTFAGWYTDSDGTTKYTFGTDVTptGDITLYA 64
Big_6 super family cl39386
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
975-1027 9.94e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


The actual alignment was detected with superfamily member pfam17936:

Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 39.15  E-value: 9.94e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2048202307  975 AATDKTLSGKGKPGATVRAYSGTSPVSKAIKIGSNGTFKLTISS-QVGGKELQV 1027
Cdd:pfam17936   11 SDDGTTLTGTGEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPaQANGETLSV 64
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
704-877 2.39e-08

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 58.09  E-value: 2.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  704 VTNLKVVSKGGEATLTWNGTVGTTFYFLDVSNDSDFASFTRYKVNERNYNLYLAPKGIHYIRVKPILTLENQDWEGSSST 783
Cdd:COG3401    147 LYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSV 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  784 VFRDSLLKKIDGIKISDVTSTSVKLSWNRQNYNH---FYVYRAED-NGIFKQVATVNTEAWTDTRLDHRKDYQYKIVGHl 859
Cdd:COG3401    227 TTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDatgYRVYRSNSgDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV- 305
                          170
                   ....*....|....*...
gi 2048202307  860 kldDTGGLLSEVSDVVSV 877
Cdd:COG3401    306 ---DAAGNESAPSNVVSV 320
Flg_new pfam09479
Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core ...
661-696 3.24e-04

Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core region of about 43 residues which occurs in more than 400 mostly secreted or cell surface-located proteins from over 300 eubacterial and few archaeal species. These proteins contain between one and 34 copies of the domain that often occur in tandem arrays with up to more than 20 copies.


Pssm-ID: 462813 [Multi-domain]  Cd Length: 65  Bit Score: 39.92  E-value: 3.24e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2048202307  661 EPTKSNHFFIGWYKDQAFTEKIDLNQDVT--ESMDLYA 696
Cdd:pfam09479   27 DPTKEGYTFAGWYTDSDGTTKYTFGTDVTptGDITLYA 64
Big_6 pfam17936
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
975-1027 9.94e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 39.15  E-value: 9.94e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2048202307  975 AATDKTLSGKGKPGATVRAYSGTSPVSKAIKIGSNGTFKLTISS-QVGGKELQV 1027
Cdd:pfam17936   11 SDDGTTLTGTGEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPaQANGETLSV 64
List_Bact_rpt TIGR02543
Listeria/Bacterioides repeat; This model describes a conserved core region, about 43 residues ...
662-702 1.19e-03

Listeria/Bacterioides repeat; This model describes a conserved core region, about 43 residues in length, of at least two families of tandem repeats. These include 78-residue repeats from 2 to 15 in number, in some proteins of Bacteroides forsythus ATCC 43037, and 70-residue repeats in families of internalins of Listeria species. Single copies are found in proteins of Fibrobacter succinogenes, Geobacter sulfurreducens, and a few bacteria. [Unknown function, General]


Pssm-ID: 274189 [Multi-domain]  Cd Length: 43  Bit Score: 37.60  E-value: 1.19e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2048202307  662 PTKSNHFFIGWYKDQAFTEKIDLNQD--VTESMDLYARFIPVP 702
Cdd:TIGR02543    1 PTKTGYTFVGWTGDSTGTPVKNFTIPsgSTGDLTLYAKWTPNT 43
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
704-877 2.39e-08

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 58.09  E-value: 2.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  704 VTNLKVVSKGGEATLTWNGTVGTTFYFLDVSNDSDFASFTRYKVNERNYNLYLAPKGIHYIRVKPILTLENQDWEGSSST 783
Cdd:COG3401    147 LYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSV 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  784 VFRDSLLKKIDGIKISDVTSTSVKLSWNRQNYNH---FYVYRAED-NGIFKQVATVNTEAWTDTRLDHRKDYQYKIVGHl 859
Cdd:COG3401    227 TTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDatgYRVYRSNSgDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAV- 305
                          170
                   ....*....|....*...
gi 2048202307  860 kldDTGGLLSEVSDVVSV 877
Cdd:COG3401    306 ---DAAGNESAPSNVVSV 320
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
705-915 4.70e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 53.85  E-value: 4.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  705 TNLKVVSKG-GEATLTW--NGTVGTTFYFLDVSNDSDFaSFTryKVNERNYNLY----LAPKGIHYIRVKPILTLENQDW 777
Cdd:COG3401    237 TGLTATADTpGSVTLSWdpVTESDATGYRVYRSNSGDG-PFT--KVATVTTTSYtdtgLTNGTTYYYRVTAVDAAGNESA 313
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2048202307  778 EGSSSTVFRD-SLLKKIDGIKISDVTSTSVKLSWNRQNYN---HFYVYRAED-NGIFKQVA-TVNTEAWTDTRLDHRKDY 851
Cdd:COG3401    314 PSNVVSVTTDlTPPAAPSGLTATAVGSSSITLSWTASSDAdvtGYNVYRSTSgGGTYTKIAeTVTTTSYTDTGLTPGTTY 393
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2048202307  852 QYKIVGHlkldDTGGLLSEVSDVVSVRLKLPYTGTWEVNPIAENSTVVTGKALEPNGHVEVYKG 915
Cdd:COG3401    394 YYKVTAV----DAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGV 453
Flg_new pfam09479
Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core ...
661-696 3.24e-04

Listeria-Bacteroides repeat domain (List_Bact_rpt); This model describes a conserved core region of about 43 residues which occurs in more than 400 mostly secreted or cell surface-located proteins from over 300 eubacterial and few archaeal species. These proteins contain between one and 34 copies of the domain that often occur in tandem arrays with up to more than 20 copies.


Pssm-ID: 462813 [Multi-domain]  Cd Length: 65  Bit Score: 39.92  E-value: 3.24e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2048202307  661 EPTKSNHFFIGWYKDQAFTEKIDLNQDVT--ESMDLYA 696
Cdd:pfam09479   27 DPTKEGYTFAGWYTDSDGTTKYTFGTDVTptGDITLYA 64
Big_6 pfam17936
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
975-1027 9.94e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 39.15  E-value: 9.94e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2048202307  975 AATDKTLSGKGKPGATVRAYSGTSPVSKAIKIGSNGTFKLTISS-QVGGKELQV 1027
Cdd:pfam17936   11 SDDGTTLTGTGEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPaQANGETLSV 64
List_Bact_rpt TIGR02543
Listeria/Bacterioides repeat; This model describes a conserved core region, about 43 residues ...
662-702 1.19e-03

Listeria/Bacterioides repeat; This model describes a conserved core region, about 43 residues in length, of at least two families of tandem repeats. These include 78-residue repeats from 2 to 15 in number, in some proteins of Bacteroides forsythus ATCC 43037, and 70-residue repeats in families of internalins of Listeria species. Single copies are found in proteins of Fibrobacter succinogenes, Geobacter sulfurreducens, and a few bacteria. [Unknown function, General]


Pssm-ID: 274189 [Multi-domain]  Cd Length: 43  Bit Score: 37.60  E-value: 1.19e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2048202307  662 PTKSNHFFIGWYKDQAFTEKIDLNQD--VTESMDLYARFIPVP 702
Cdd:TIGR02543    1 PTKTGYTFVGWTGDSTGTPVKNFTIPsgSTGDLTLYAKWTPNT 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH