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Concise Results
Standard Results
Full Results
malate synthase G [Pseudoalteromonas sp. SiA1]
Protein Classification
malate synthase G ( domain architecture ID 10011891 )
malate synthase G catalyzes the formation of malate from glyoxylate and acetyl-CoA
List of domain hits
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-725
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1463.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 1 M SHTLTHS GL S V DKQ L AE FV KKQL LPGT HL D EHQ FW KS FA N IV QT L T P L N KS LLAKR EQ LQ KQ ID DY H L A NKNA -- D Q A Q 78
Cdd:PRK02999 1 M TERVQVG GL Q V AAV L YD FV NNEA LPGT GV D ADA FW AG FA A IV HD L A P K N RA LLAKR DE LQ AK ID AW H R A HPGP ph D L A A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 79 Y Q AFL KD IGYLV D EPE N F S I E T Q NV E PEIA LT AGPQLVVPV S NAR F ALNAANARWGSLYDALYGTD VLS E DD GAEKG SQ Y 158
Cdd:PRK02999 81 Y K AFL TE IGYLV P EPE D F T I T T E NV D PEIA TQ AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD AIP E EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 159 NPVRG F KV M AYAR Q FLD K A L PL EN GSH IES T N Y SIV DG A L AI TL R D S S H T T L KN P E Q LI GYQG E A QN PS V ILLKNNGLHI 238
Cdd:PRK02999 161 NPVRG A KV I AYAR A FLD E A A PL AS GSH ADV T G Y AVE DG Q L VV TL K D G S E T G L AD P A Q FV GYQG D A AA PS A ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 239 E L QID HH HPIG QA D K AG L KDVVLE A ALTTIMDCEDSVAAVDAEDKV Q VY K NWLGLM Q G N L V E T F R KG D K MID R T L QA DR Q 318
Cdd:PRK02999 241 E I QID RN HPIG KT D P AG V KDVVLE S ALTTIMDCEDSVAAVDAEDKV L VY R NWLGLM K G D L T E E F E KG G K TFT R R L NP DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 319 YT GL DG QK LTL K GRS MM FVRNVGHLMTNPAI T D VS GN DVF EGI M DA MF T ATA ALHDL NTKNTIK NS TAQ S IN IVKPKMHG 398
Cdd:PRK02999 321 YT AP DG GE LTL H GRS LL FVRNVGHLMTNPAI L D AD GN EIP EGI L DA VV T SLI ALHDL KGNGRRR NS RTG S VY IVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 399 P D EVAFAN T LFG M VE EA L S LP K NTLK M GIMDEERRTS A NLKACI H AAK E RVVFINTGFLDRTGDEIHTSM Q AG VVLP K AA 478
Cdd:PRK02999 401 P E EVAFAN E LFG R VE DL L G LP R NTLK V GIMDEERRTS V NLKACI R AAK D RVVFINTGFLDRTGDEIHTSM E AG PMVR K GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 479 I K AQ PWI S AYED R NVDIGLACGL SHK AQIGKGMWAMPD K MA M M M EQKIAHP QS GANTAWVPSPTAATLHA M HYH D VDVF S 558
Cdd:PRK02999 481 M K SS PWI A AYED N NVDIGLACGL RGR AQIGKGMWAMPD L MA D M L EQKIAHP KA GANTAWVPSPTAATLHA L HYH Q VDVF A 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 559 L Q QSI A - TR QI ASL ES LLT P PL MP N P e TL S K E D IQ S EL E NNAQGILGYVVRW I DQG I GCSKVPDI NHI GLMEDRATLRIS 637
Cdd:PRK02999 561 V Q AEL A k TR PR ASL DD LLT I PL AE N A - NW S A E E IQ Q EL D NNAQGILGYVVRW V DQG V GCSKVPDI HDV GLMEDRATLRIS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 638 SQHIANWL H HGV CSK EQV QKVMAK MA K VVD G QN EH D SL Y T PMA TN eqt LAK SIA Y QAA LA LVF E G VS QP S GYTEPLLH SY 717
Cdd:PRK02999 640 SQHIANWL R HGV VTE EQV MESLKR MA A VVD Q QN AG D PA Y R PMA PD --- FDN SIA F QAA CD LVF K G RE QP N GYTEPLLH AR 716
....*...
gi 2049888662 718 RL KY KA QH 725
Cdd:PRK02999 717 RL EA KA KQ 724
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-725
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1463.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 1 M SHTLTHS GL S V DKQ L AE FV KKQL LPGT HL D EHQ FW KS FA N IV QT L T P L N KS LLAKR EQ LQ KQ ID DY H L A NKNA -- D Q A Q 78
Cdd:PRK02999 1 M TERVQVG GL Q V AAV L YD FV NNEA LPGT GV D ADA FW AG FA A IV HD L A P K N RA LLAKR DE LQ AK ID AW H R A HPGP ph D L A A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 79 Y Q AFL KD IGYLV D EPE N F S I E T Q NV E PEIA LT AGPQLVVPV S NAR F ALNAANARWGSLYDALYGTD VLS E DD GAEKG SQ Y 158
Cdd:PRK02999 81 Y K AFL TE IGYLV P EPE D F T I T T E NV D PEIA TQ AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD AIP E EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 159 NPVRG F KV M AYAR Q FLD K A L PL EN GSH IES T N Y SIV DG A L AI TL R D S S H T T L KN P E Q LI GYQG E A QN PS V ILLKNNGLHI 238
Cdd:PRK02999 161 NPVRG A KV I AYAR A FLD E A A PL AS GSH ADV T G Y AVE DG Q L VV TL K D G S E T G L AD P A Q FV GYQG D A AA PS A ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 239 E L QID HH HPIG QA D K AG L KDVVLE A ALTTIMDCEDSVAAVDAEDKV Q VY K NWLGLM Q G N L V E T F R KG D K MID R T L QA DR Q 318
Cdd:PRK02999 241 E I QID RN HPIG KT D P AG V KDVVLE S ALTTIMDCEDSVAAVDAEDKV L VY R NWLGLM K G D L T E E F E KG G K TFT R R L NP DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 319 YT GL DG QK LTL K GRS MM FVRNVGHLMTNPAI T D VS GN DVF EGI M DA MF T ATA ALHDL NTKNTIK NS TAQ S IN IVKPKMHG 398
Cdd:PRK02999 321 YT AP DG GE LTL H GRS LL FVRNVGHLMTNPAI L D AD GN EIP EGI L DA VV T SLI ALHDL KGNGRRR NS RTG S VY IVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 399 P D EVAFAN T LFG M VE EA L S LP K NTLK M GIMDEERRTS A NLKACI H AAK E RVVFINTGFLDRTGDEIHTSM Q AG VVLP K AA 478
Cdd:PRK02999 401 P E EVAFAN E LFG R VE DL L G LP R NTLK V GIMDEERRTS V NLKACI R AAK D RVVFINTGFLDRTGDEIHTSM E AG PMVR K GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 479 I K AQ PWI S AYED R NVDIGLACGL SHK AQIGKGMWAMPD K MA M M M EQKIAHP QS GANTAWVPSPTAATLHA M HYH D VDVF S 558
Cdd:PRK02999 481 M K SS PWI A AYED N NVDIGLACGL RGR AQIGKGMWAMPD L MA D M L EQKIAHP KA GANTAWVPSPTAATLHA L HYH Q VDVF A 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 559 L Q QSI A - TR QI ASL ES LLT P PL MP N P e TL S K E D IQ S EL E NNAQGILGYVVRW I DQG I GCSKVPDI NHI GLMEDRATLRIS 637
Cdd:PRK02999 561 V Q AEL A k TR PR ASL DD LLT I PL AE N A - NW S A E E IQ Q EL D NNAQGILGYVVRW V DQG V GCSKVPDI HDV GLMEDRATLRIS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 638 SQHIANWL H HGV CSK EQV QKVMAK MA K VVD G QN EH D SL Y T PMA TN eqt LAK SIA Y QAA LA LVF E G VS QP S GYTEPLLH SY 717
Cdd:PRK02999 640 SQHIANWL R HGV VTE EQV MESLKR MA A VVD Q QN AG D PA Y R PMA PD --- FDN SIA F QAA CD LVF K G RE QP N GYTEPLLH AR 716
....*...
gi 2049888662 718 RL KY KA QH 725
Cdd:PRK02999 717 RL EA KA KQ 724
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-722
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1251.54
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 9 G L S V DKQ L AE FV KKQL LPGT HL D EHQ FW KS F AN IV QT LTP L N KS LLAKR EQ LQ KQ IDD Y H LA N KNA -- DQA Q Y QA FLK D I 86
Cdd:cd00728 1 N L R V AGC L YD FV NEEA LPGT GI D ADA FW AG F DE IV HD LTP R N RA LLAKR DE LQ AK IDD W H RD N PGP pl DQA A Y KK FLK E I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 87 GYLV D EP EN F S I E T Q NV EP EIA LT AGPQLVVP VS NAR F ALNAANARWGSLYDALYGTDV LS E DD GAE K G SQ YNPVRG F KV 166
Cdd:cd00728 81 GYLV P EP AD F T I T T D NV DD EIA TQ AGPQLVVP LM NAR Y ALNAANARWGSLYDALYGTDV IP E EN GAE R G KG YNPVRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 167 M AYAR Q FLD KAL PL E NGSH IES T N Y SI VDG A L AI TL R D SSH TTLK N P E Q LI GY Q G E A QN PS VI LLK N NGLHIE L QID HH H 246
Cdd:cd00728 161 I AYAR R FLD ESV PL T NGSH ADA T G Y KV VDG Q L VV TL D D GKT TTLK D P A Q FV GY R G D A NA PS AV LLK H NGLHIE I QID RN H 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 247 P IG QA D K AG L KDVV L EAALTTIMDCEDSVAAVDAEDKV Q VY K NWLGLM Q G N L V E TFR K GDKMID R T L Q ADR Q YT GL DG QK 326
Cdd:cd00728 241 Q IG KT D P AG V KDVV V EAALTTIMDCEDSVAAVDAEDKV L VY R NWLGLM K G D L A E EVE K NGRTFT R K L N ADR N YT TP DG GE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 327 L TL K GRS M MFVRNVGHLMTN P AI T D VS GN D V F EGIMDA MF T ATA ALHDL NTKNTIK NS TAQ SI N IVKPKMHGP D EVAFAN 406
Cdd:cd00728 321 I TL P GRS L MFVRNVGHLMTN D AI L D SD GN E V P EGIMDA VI T SLI ALHDL KGNSAFG NS RTG SI Y IVKPKMHGP E EVAFAN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 407 T LF GM VE EA L S LP K NT L KMGIMDEERRTS A NLK A CI H AA KE RVVFINTGFLDRTGDEIHTSM Q AG VVLP KA AI K AQ PWI S 486
Cdd:cd00728 401 E LF SR VE DL L G LP Q NT I KMGIMDEERRTS V NLK E CI R AA RD RVVFINTGFLDRTGDEIHTSM E AG PMAR KA DM K SS PWI G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 487 AYED R NVDIGLA C GLS H KAQIGKGMWAMPD K MA M MMEQKIAHP QS GANTAWVPSPTAATLHA M HYH D V D VF SL Q QSI A T R 566
Cdd:cd00728 481 AYED N NVDIGLA A GLS G KAQIGKGMWAMPD L MA D MMEQKIAHP KA GANTAWVPSPTAATLHA L HYH Q V N VF AV Q KEL A K R 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 567 QI A S L ES LLT P PL MP N P e TL S KED IQSEL E NN A QGILGYVVRW I DQGIGCSKVPDIN HI GLMEDRATLRISSQHIANWL H 646
Cdd:cd00728 561 RP A D L DD LLT I PL AE N A - NW S PQE IQSEL D NN V QGILGYVVRW V DQGIGCSKVPDIN NV GLMEDRATLRISSQHIANWL R 639
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049888662 647 HG V C S KEQVQ KVMAK MAKVVD G QN EH D SL Y T PMA TN eqt LAK SIA YQ AA LA L V F E G VS QP S GYTEPLLH SY RL KY K 722
Cdd:cd00728 640 HG I C T KEQVQ ESLER MAKVVD Q QN AG D PS Y R PMA PD --- FDD SIA FK AA CD L I F Q G KE QP N GYTEPLLH AR RL EK K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
4-725
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1061.07
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 4 T L T HSG L S V DKQ L AE FV KKQL LPGT H LD EHQ FW KS F AN IV QT L T P L N KS LLA K R EQL Q KQ ID DY H LA N KNA - D Q A Q Y QA F 82
Cdd:TIGR01345 2 T I T QGR L Q V AAN L KR FV DEEV LPGT G LD AAA FW SG F DE IV HD L A P E N RQ LLA E R DEI Q AA ID EW H RS N PGP i D K A A Y KS F 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 83 L KD IGYLV DE PE NFS IET Q NV EP EI ALT AGPQLVVP VS NAR F ALNAANARWGSLYDALYG TDVLS E D DG A EKG SQ YNP V R 162
Cdd:TIGR01345 82 L RE IGYLV PQ PE RVT IET T NV DS EI TSQ AGPQLVVP AM NAR Y ALNAANARWGSLYDALYG SNIIP E E DG M EKG KE YNP Q R 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 163 G F KV M A YA R Q FLD KA LPLENGSH IESTN Y S IVD GA L A I T L RDSSH T T LK N P E Q LI GY Q G E A QN P SV ILLKNNGLHIELQI 242
Cdd:TIGR01345 162 G E KV I A WV R R FLD ES LPLENGSH QDVVA Y K IVD KQ L R I Q L KNGKE T R LK T P A Q FV GY R G D A AD P TC ILLKNNGLHIELQI 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 243 D HH HPIG QA D K A GL KD V VLE A A L TTIMDCEDSVAAVDAEDK VQV Y K NWLGLMQG N L V E TFR K GDKM I D R T L QA DR Q YT GL 322
Cdd:TIGR01345 242 D AN HPIG KD D P A HI KD I VLE S A I TTIMDCEDSVAAVDAEDK ILL Y R NWLGLMQG T L Q E KME K NGRQ I V R K L ND DR H YT AA 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 323 D G QKLT L K GRS MM FVRNVGHLMT N P A I T D VS G NDVF EGI M D AMF T ATA AL H DL NTK N TIK NS TAQ S IN IVKPKMHGP D EV 402
Cdd:TIGR01345 322 N G SEIS L H GRS LL FVRNVGHLMT I P V I W D SE G EEIP EGI L D GVM T GAI AL Y DL KVQ N KMR NS RKG S VY IVKPKMHGP E EV 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 403 AFAN T LF GMV E EA L S L PKN TLKMG I MDEERRTS A NL K ACI HAAKE RV V FINTGFLDRTGDEIHTSM Q AG VV L P K AAI K AQ 482
Cdd:TIGR01345 402 AFAN K LF TRI E DM L G L ARH TLKMG V MDEERRTS L NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSM E AG PM L R K NDM K ST 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 483 PWI S AYE DR NV DI GL A CGL SH KAQIGKGMWAMPD K MA M M M EQK IAHPQS GANTAWVPSPTAATLHA M HYH DVD V F S L Q QS 562
Cdd:TIGR01345 482 PWI K AYE RN NV LA GL F CGL RG KAQIGKGMWAMPD L MA E M Y EQK GDQLRA GANTAWVPSPTAATLHA L HYH QTN V Q S V Q AN 561
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 563 I A - T RQI A S L ESL LT P P LMP N PE t L S K E D IQ S EL E NN A QGILGYVVRW ID QGIGCSKVPDI NHIG LMEDRATLRISSQHI 641
Cdd:TIGR01345 562 L A q T EFN A E L DDI LT I P VAE N TN - W S A E E IQ Q EL D NN V QGILGYVVRW VE QGIGCSKVPDI HNVA LMEDRATLRISSQHI 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 642 ANWL H HG VC SKEQVQ KVMAK MAKVVD G QN EH D SL Y T PMA T N eqt L A K S I A Y QAA LA L V F E G VS QPSGYTEP L LH SY RL KY 721
Cdd:TIGR01345 641 ANWL R HG IV SKEQVQ ASLER MAKVVD Q QN AG D PA Y R PMA G N --- F A N S C A F QAA SD L I F L G TK QPSGYTEP I LH AR RL EF 717
....
gi 2049888662 722 K AQ H 725
Cdd:TIGR01345 718 K EK H 721
Malate_synthase
pfam01274 Malate synthase;
18-671
3.35e-152
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 452.62
E-value: 3.35e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 18 E FV KKQL LPGT HLDEHQFWKSF A NIVQTL TP LNKS LLA K R EQL Q KQ ID DY HL AN knadqaqyqa FL KDI GY LVDE P E nfs 97
Cdd:pfam01274 2 D FV GPYV LPGT GILTKEALSFV A ELHRDF TP RRRE LLA R R DER Q AR ID AG HL PD ---------- FL PET GY IRPD P D --- 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 98 ietqnvepeialtagpqlvvpvsnarfalnaanar W gslydalygtdvlseddgaekgsqynpvrgfkvmayarqfldka 177
Cdd:pfam01274 69 ----------------------------------- W -------------------------------------------- 69
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 178 lplengshiestnysivdgalaitlrdsshttlknpeqligyqgeaqnpsvill K NNG LH I ELQ IDHHHPI G Q AD KAGLK 257
Cdd:pfam01274 70 ------------------------------------------------------ K TAT LH P ELQ DRRVEIT G P AD RKMII 95
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 258 DVVLEA A L TT IM D C EDSVA A vdaedkvqvyk N W LG L M QG N L VETFRKGDKMID R T L Q A DRQ Y TGL DG qklt L K GR SMM FV 337
Cdd:pfam01274 96 NALNSG A I TT MA D F EDSVA P ----------- T W NN L I QG Q L NLYDAVRGRIDF R D L N A GKS Y KLN DG ---- L H GR ATL FV 160
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 338 R NV G HLMTNPA I T d V S G NDVFE GI M D A mft ATAAL H DLNTK N tikn S TAQSINIVK PKM HGPD E V A FA N TL F GMV E EA L S 417
Cdd:pfam01274 161 R PR G WHLPEKH I L - V D G EPIPG GI F D F --- GLYFF H NAKEL N ---- S RGGGPYFYL PKM EHHQ E A A LW N DV F NRA E DY L G 232
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 418 L P KN T LKMGIMD E ERRT S ANLKAC I HAAKERVVFI N T G FL D RTGDE I H T SMQ A G - V VLP -- KA AIKAQ P WIS AYE DRNVD 494
Cdd:pfam01274 233 I P RG T IRATVLI E TLPA S FQMDEI I YELRDHSAGL N C G RW D YIFSY I K T LRN A P d M VLP dr KA VTMTA P FMR AYE KLLIK 312
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 495 I ------ GLAC G LSHKAQ I GKG M W A MPDK M AMMMEQ K IAHPQS G ANTA WV PS P TA A T L H A MHY H D V D V FSL Q QSI A TRQI 568
Cdd:pfam01274 313 T chkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREVRA G HDGT WV AH P GL A P L A A EVF H Q V M V RPN Q IEL A REED 392
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 569 - ASLES LLT P P L mpnpetls K E DIQSE L E NN A Q GI L G YV VR W I d Q G I GC sk VP D I N hig LMED R AT LR IS S Q HIAN WL H H 647
Cdd:pfam01274 393 s ITADD LLT I P D -------- G E ETEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I I H --- LMED A AT AE IS R Q QLWQ WL R H 458
650 660
....*....|....*....|....
gi 2049888662 648 GV CSK E Q V QKVMAK MAK V VD GQ N E 671
Cdd:pfam01274 459 GV TLD E G V RVTLEL MAK L VD EE N A 482
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
605-665
2.25e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 41.24
E-value: 2.25e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 605 Y VVR W I d Q G I G C sk VP d I NH ig LMED R AT LR IS - SQ h IAN W L HHG V ------- CSK E Q V QKVM A K - M AK V 665
Cdd:COG2225 425 Y LEA W L - R G N G A -- VP - I YN -- LMED A AT AE IS r SQ - VWQ W I HHG A tlddgrk VTA E L V RQLL A E e L AK L 487
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-725
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1463.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 1 M SHTLTHS GL S V DKQ L AE FV KKQL LPGT HL D EHQ FW KS FA N IV QT L T P L N KS LLAKR EQ LQ KQ ID DY H L A NKNA -- D Q A Q 78
Cdd:PRK02999 1 M TERVQVG GL Q V AAV L YD FV NNEA LPGT GV D ADA FW AG FA A IV HD L A P K N RA LLAKR DE LQ AK ID AW H R A HPGP ph D L A A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 79 Y Q AFL KD IGYLV D EPE N F S I E T Q NV E PEIA LT AGPQLVVPV S NAR F ALNAANARWGSLYDALYGTD VLS E DD GAEKG SQ Y 158
Cdd:PRK02999 81 Y K AFL TE IGYLV P EPE D F T I T T E NV D PEIA TQ AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD AIP E EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 159 NPVRG F KV M AYAR Q FLD K A L PL EN GSH IES T N Y SIV DG A L AI TL R D S S H T T L KN P E Q LI GYQG E A QN PS V ILLKNNGLHI 238
Cdd:PRK02999 161 NPVRG A KV I AYAR A FLD E A A PL AS GSH ADV T G Y AVE DG Q L VV TL K D G S E T G L AD P A Q FV GYQG D A AA PS A ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 239 E L QID HH HPIG QA D K AG L KDVVLE A ALTTIMDCEDSVAAVDAEDKV Q VY K NWLGLM Q G N L V E T F R KG D K MID R T L QA DR Q 318
Cdd:PRK02999 241 E I QID RN HPIG KT D P AG V KDVVLE S ALTTIMDCEDSVAAVDAEDKV L VY R NWLGLM K G D L T E E F E KG G K TFT R R L NP DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 319 YT GL DG QK LTL K GRS MM FVRNVGHLMTNPAI T D VS GN DVF EGI M DA MF T ATA ALHDL NTKNTIK NS TAQ S IN IVKPKMHG 398
Cdd:PRK02999 321 YT AP DG GE LTL H GRS LL FVRNVGHLMTNPAI L D AD GN EIP EGI L DA VV T SLI ALHDL KGNGRRR NS RTG S VY IVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 399 P D EVAFAN T LFG M VE EA L S LP K NTLK M GIMDEERRTS A NLKACI H AAK E RVVFINTGFLDRTGDEIHTSM Q AG VVLP K AA 478
Cdd:PRK02999 401 P E EVAFAN E LFG R VE DL L G LP R NTLK V GIMDEERRTS V NLKACI R AAK D RVVFINTGFLDRTGDEIHTSM E AG PMVR K GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 479 I K AQ PWI S AYED R NVDIGLACGL SHK AQIGKGMWAMPD K MA M M M EQKIAHP QS GANTAWVPSPTAATLHA M HYH D VDVF S 558
Cdd:PRK02999 481 M K SS PWI A AYED N NVDIGLACGL RGR AQIGKGMWAMPD L MA D M L EQKIAHP KA GANTAWVPSPTAATLHA L HYH Q VDVF A 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 559 L Q QSI A - TR QI ASL ES LLT P PL MP N P e TL S K E D IQ S EL E NNAQGILGYVVRW I DQG I GCSKVPDI NHI GLMEDRATLRIS 637
Cdd:PRK02999 561 V Q AEL A k TR PR ASL DD LLT I PL AE N A - NW S A E E IQ Q EL D NNAQGILGYVVRW V DQG V GCSKVPDI HDV GLMEDRATLRIS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 638 SQHIANWL H HGV CSK EQV QKVMAK MA K VVD G QN EH D SL Y T PMA TN eqt LAK SIA Y QAA LA LVF E G VS QP S GYTEPLLH SY 717
Cdd:PRK02999 640 SQHIANWL R HGV VTE EQV MESLKR MA A VVD Q QN AG D PA Y R PMA PD --- FDN SIA F QAA CD LVF K G RE QP N GYTEPLLH AR 716
....*...
gi 2049888662 718 RL KY KA QH 725
Cdd:PRK02999 717 RL EA KA KQ 724
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-722
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1251.54
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 9 G L S V DKQ L AE FV KKQL LPGT HL D EHQ FW KS F AN IV QT LTP L N KS LLAKR EQ LQ KQ IDD Y H LA N KNA -- DQA Q Y QA FLK D I 86
Cdd:cd00728 1 N L R V AGC L YD FV NEEA LPGT GI D ADA FW AG F DE IV HD LTP R N RA LLAKR DE LQ AK IDD W H RD N PGP pl DQA A Y KK FLK E I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 87 GYLV D EP EN F S I E T Q NV EP EIA LT AGPQLVVP VS NAR F ALNAANARWGSLYDALYGTDV LS E DD GAE K G SQ YNPVRG F KV 166
Cdd:cd00728 81 GYLV P EP AD F T I T T D NV DD EIA TQ AGPQLVVP LM NAR Y ALNAANARWGSLYDALYGTDV IP E EN GAE R G KG YNPVRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 167 M AYAR Q FLD KAL PL E NGSH IES T N Y SI VDG A L AI TL R D SSH TTLK N P E Q LI GY Q G E A QN PS VI LLK N NGLHIE L QID HH H 246
Cdd:cd00728 161 I AYAR R FLD ESV PL T NGSH ADA T G Y KV VDG Q L VV TL D D GKT TTLK D P A Q FV GY R G D A NA PS AV LLK H NGLHIE I QID RN H 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 247 P IG QA D K AG L KDVV L EAALTTIMDCEDSVAAVDAEDKV Q VY K NWLGLM Q G N L V E TFR K GDKMID R T L Q ADR Q YT GL DG QK 326
Cdd:cd00728 241 Q IG KT D P AG V KDVV V EAALTTIMDCEDSVAAVDAEDKV L VY R NWLGLM K G D L A E EVE K NGRTFT R K L N ADR N YT TP DG GE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 327 L TL K GRS M MFVRNVGHLMTN P AI T D VS GN D V F EGIMDA MF T ATA ALHDL NTKNTIK NS TAQ SI N IVKPKMHGP D EVAFAN 406
Cdd:cd00728 321 I TL P GRS L MFVRNVGHLMTN D AI L D SD GN E V P EGIMDA VI T SLI ALHDL KGNSAFG NS RTG SI Y IVKPKMHGP E EVAFAN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 407 T LF GM VE EA L S LP K NT L KMGIMDEERRTS A NLK A CI H AA KE RVVFINTGFLDRTGDEIHTSM Q AG VVLP KA AI K AQ PWI S 486
Cdd:cd00728 401 E LF SR VE DL L G LP Q NT I KMGIMDEERRTS V NLK E CI R AA RD RVVFINTGFLDRTGDEIHTSM E AG PMAR KA DM K SS PWI G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 487 AYED R NVDIGLA C GLS H KAQIGKGMWAMPD K MA M MMEQKIAHP QS GANTAWVPSPTAATLHA M HYH D V D VF SL Q QSI A T R 566
Cdd:cd00728 481 AYED N NVDIGLA A GLS G KAQIGKGMWAMPD L MA D MMEQKIAHP KA GANTAWVPSPTAATLHA L HYH Q V N VF AV Q KEL A K R 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 567 QI A S L ES LLT P PL MP N P e TL S KED IQSEL E NN A QGILGYVVRW I DQGIGCSKVPDIN HI GLMEDRATLRISSQHIANWL H 646
Cdd:cd00728 561 RP A D L DD LLT I PL AE N A - NW S PQE IQSEL D NN V QGILGYVVRW V DQGIGCSKVPDIN NV GLMEDRATLRISSQHIANWL R 639
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049888662 647 HG V C S KEQVQ KVMAK MAKVVD G QN EH D SL Y T PMA TN eqt LAK SIA YQ AA LA L V F E G VS QP S GYTEPLLH SY RL KY K 722
Cdd:cd00728 640 HG I C T KEQVQ ESLER MAKVVD Q QN AG D PS Y R PMA PD --- FDD SIA FK AA CD L I F Q G KE QP N GYTEPLLH AR RL EK K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
4-725
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1061.07
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 4 T L T HSG L S V DKQ L AE FV KKQL LPGT H LD EHQ FW KS F AN IV QT L T P L N KS LLA K R EQL Q KQ ID DY H LA N KNA - D Q A Q Y QA F 82
Cdd:TIGR01345 2 T I T QGR L Q V AAN L KR FV DEEV LPGT G LD AAA FW SG F DE IV HD L A P E N RQ LLA E R DEI Q AA ID EW H RS N PGP i D K A A Y KS F 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 83 L KD IGYLV DE PE NFS IET Q NV EP EI ALT AGPQLVVP VS NAR F ALNAANARWGSLYDALYG TDVLS E D DG A EKG SQ YNP V R 162
Cdd:TIGR01345 82 L RE IGYLV PQ PE RVT IET T NV DS EI TSQ AGPQLVVP AM NAR Y ALNAANARWGSLYDALYG SNIIP E E DG M EKG KE YNP Q R 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 163 G F KV M A YA R Q FLD KA LPLENGSH IESTN Y S IVD GA L A I T L RDSSH T T LK N P E Q LI GY Q G E A QN P SV ILLKNNGLHIELQI 242
Cdd:TIGR01345 162 G E KV I A WV R R FLD ES LPLENGSH QDVVA Y K IVD KQ L R I Q L KNGKE T R LK T P A Q FV GY R G D A AD P TC ILLKNNGLHIELQI 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 243 D HH HPIG QA D K A GL KD V VLE A A L TTIMDCEDSVAAVDAEDK VQV Y K NWLGLMQG N L V E TFR K GDKM I D R T L QA DR Q YT GL 322
Cdd:TIGR01345 242 D AN HPIG KD D P A HI KD I VLE S A I TTIMDCEDSVAAVDAEDK ILL Y R NWLGLMQG T L Q E KME K NGRQ I V R K L ND DR H YT AA 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 323 D G QKLT L K GRS MM FVRNVGHLMT N P A I T D VS G NDVF EGI M D AMF T ATA AL H DL NTK N TIK NS TAQ S IN IVKPKMHGP D EV 402
Cdd:TIGR01345 322 N G SEIS L H GRS LL FVRNVGHLMT I P V I W D SE G EEIP EGI L D GVM T GAI AL Y DL KVQ N KMR NS RKG S VY IVKPKMHGP E EV 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 403 AFAN T LF GMV E EA L S L PKN TLKMG I MDEERRTS A NL K ACI HAAKE RV V FINTGFLDRTGDEIHTSM Q AG VV L P K AAI K AQ 482
Cdd:TIGR01345 402 AFAN K LF TRI E DM L G L ARH TLKMG V MDEERRTS L NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSM E AG PM L R K NDM K ST 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 483 PWI S AYE DR NV DI GL A CGL SH KAQIGKGMWAMPD K MA M M M EQK IAHPQS GANTAWVPSPTAATLHA M HYH DVD V F S L Q QS 562
Cdd:TIGR01345 482 PWI K AYE RN NV LA GL F CGL RG KAQIGKGMWAMPD L MA E M Y EQK GDQLRA GANTAWVPSPTAATLHA L HYH QTN V Q S V Q AN 561
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 563 I A - T RQI A S L ESL LT P P LMP N PE t L S K E D IQ S EL E NN A QGILGYVVRW ID QGIGCSKVPDI NHIG LMEDRATLRISSQHI 641
Cdd:TIGR01345 562 L A q T EFN A E L DDI LT I P VAE N TN - W S A E E IQ Q EL D NN V QGILGYVVRW VE QGIGCSKVPDI HNVA LMEDRATLRISSQHI 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 642 ANWL H HG VC SKEQVQ KVMAK MAKVVD G QN EH D SL Y T PMA T N eqt L A K S I A Y QAA LA L V F E G VS QPSGYTEP L LH SY RL KY 721
Cdd:TIGR01345 641 ANWL R HG IV SKEQVQ ASLER MAKVVD Q QN AG D PA Y R PMA G N --- F A N S C A F QAA SD L I F L G TK QPSGYTEP I LH AR RL EF 717
....
gi 2049888662 722 K AQ H 725
Cdd:TIGR01345 718 K EK H 721
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
35-718
6.50e-167
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 489.82
E-value: 6.50e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 35 FWKSF A NIVQTLT P LNKS LLA K R EQL Q KQI D DY H L anknadqaq YQA FL KDIG Y L v DEPENFSIETQ -- NVEPEIALTA G 112
Cdd:cd00480 1 ALAFV A ELHREFN P RRRE LLA A R DER Q ARL D AG H A --------- LPD FL PETA Y I - RRDGDWKVAPD pp DLDDRRVEIT G 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 113 PQ LVVP V S NA RFALN A anarwgslydalygtdvlseddgaekgsqynpvrgfkvmayarqfldkalplengshiestnys 192
Cdd:cd00480 71 PQ DRKM V I NA LNSGA A ---------------------------------------------------------------- 86
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 193 ivdgalaitlrdsshttlknpeqligyqgeaqnpsvillknnglhielqidhhhpigqadkaglkdvvleaal TTIM D C E 272
Cdd:cd00480 87 ------------------------------------------------------------------------- VFMA D F E 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 273 DS V A AV d A E D KV QVYK N W L GLMQ G NLVE T FR K GD K MIDRT L qadrqytgldgqklt L K GR SMM FVR NV G HLM T NPA I T d V 352
Cdd:cd00480 94 DS S A PT - W E N KV EGQR N L L DAVR G TISF T DS K NG K SYRLN L --------------- L D GR ATL FVR PR G WHL T EKH I L - V 156
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 353 S G ND V FE G IM D AMFTATAAL H D L NTK ntiknst AQSINIVK PKM HG P D E VAFA N TL F GMV E EA L S LP KN T L K MGIMD E ER 432
Cdd:cd00480 157 D G EP V PG G LF D FGLYFFHNA H A L KAR ------- GSGPYFYL PKM ES P L E ARLW N DV F SRA E DY L G LP RG T I K ATVLI E TL 229
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 433 RTSANLKACIHAAKERVVFI N T G FL D RTGD EI H T SM - QAGV VLP -- KAAIKAQ P WIS AYE DRN V DIGLAC G L ---- SHK A 505
Cdd:cd00480 230 PAAFEMDEILYELRDHSAGL N C G RW D YIFS EI K T FR n HPDF VLP dr AKVTMTS P FMR AYE KLL V KTCHRR G A hamg GMA A 309
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 506 QI G - KG MW A MPDK - MA MMMEQ K IAHPQS G ANTA WV PS P TA A T L H A MHY H D V DVFSL Q QSIATRQI - ASLES LLT P P LMPN 582
Cdd:cd00480 310 QI P i KG DP A ANEA a MA KVRAD K LREAKA G HDGT WV AH P GL A P L A A LVF H K V MPGPN Q LFRKREDV k VTADD LLT I P VAEG 389
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 583 PE T lskedi QSE L E NN A Q GI LGYVV R W ID qgi G CSK VP D IN hig LMED R AT LR IS SQHIAN WL H HGVC SKEQ V QKVMAKM 662
Cdd:cd00480 390 DI T ------ EEG L R NN I Q VA LGYVV A W LN --- G NGA VP I IN --- LMED A AT AE IS RSQLWQ WL R HGVC LDDG V PVTLELV 457
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 2049888662 663 AK V VD GQ N EHDSL Y T P matne QTLAK SIA YQA A LA L V FEGV --- SQ P SGY TEPL L H SY R 718
Cdd:cd00480 458 AK L VD EE N ARLPA Y R P ----- PNFFD SIA FKE A AD L F FEGV tae EF P EFL TEPL Y H LL R 511
Malate_synthase
pfam01274 Malate synthase;
18-671
3.35e-152
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 452.62
E-value: 3.35e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 18 E FV KKQL LPGT HLDEHQFWKSF A NIVQTL TP LNKS LLA K R EQL Q KQ ID DY HL AN knadqaqyqa FL KDI GY LVDE P E nfs 97
Cdd:pfam01274 2 D FV GPYV LPGT GILTKEALSFV A ELHRDF TP RRRE LLA R R DER Q AR ID AG HL PD ---------- FL PET GY IRPD P D --- 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 98 ietqnvepeialtagpqlvvpvsnarfalnaanar W gslydalygtdvlseddgaekgsqynpvrgfkvmayarqfldka 177
Cdd:pfam01274 69 ----------------------------------- W -------------------------------------------- 69
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 178 lplengshiestnysivdgalaitlrdsshttlknpeqligyqgeaqnpsvill K NNG LH I ELQ IDHHHPI G Q AD KAGLK 257
Cdd:pfam01274 70 ------------------------------------------------------ K TAT LH P ELQ DRRVEIT G P AD RKMII 95
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 258 DVVLEA A L TT IM D C EDSVA A vdaedkvqvyk N W LG L M QG N L VETFRKGDKMID R T L Q A DRQ Y TGL DG qklt L K GR SMM FV 337
Cdd:pfam01274 96 NALNSG A I TT MA D F EDSVA P ----------- T W NN L I QG Q L NLYDAVRGRIDF R D L N A GKS Y KLN DG ---- L H GR ATL FV 160
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 338 R NV G HLMTNPA I T d V S G NDVFE GI M D A mft ATAAL H DLNTK N tikn S TAQSINIVK PKM HGPD E V A FA N TL F GMV E EA L S 417
Cdd:pfam01274 161 R PR G WHLPEKH I L - V D G EPIPG GI F D F --- GLYFF H NAKEL N ---- S RGGGPYFYL PKM EHHQ E A A LW N DV F NRA E DY L G 232
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 418 L P KN T LKMGIMD E ERRT S ANLKAC I HAAKERVVFI N T G FL D RTGDE I H T SMQ A G - V VLP -- KA AIKAQ P WIS AYE DRNVD 494
Cdd:pfam01274 233 I P RG T IRATVLI E TLPA S FQMDEI I YELRDHSAGL N C G RW D YIFSY I K T LRN A P d M VLP dr KA VTMTA P FMR AYE KLLIK 312
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 495 I ------ GLAC G LSHKAQ I GKG M W A MPDK M AMMMEQ K IAHPQS G ANTA WV PS P TA A T L H A MHY H D V D V FSL Q QSI A TRQI 568
Cdd:pfam01274 313 T chkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREVRA G HDGT WV AH P GL A P L A A EVF H Q V M V RPN Q IEL A REED 392
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 569 - ASLES LLT P P L mpnpetls K E DIQSE L E NN A Q GI L G YV VR W I d Q G I GC sk VP D I N hig LMED R AT LR IS S Q HIAN WL H H 647
Cdd:pfam01274 393 s ITADD LLT I P D -------- G E ETEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I I H --- LMED A AT AE IS R Q QLWQ WL R H 458
650 660
....*....|....*....|....
gi 2049888662 648 GV CSK E Q V QKVMAK MAK V VD GQ N E 671
Cdd:pfam01274 459 GV TLD E G V RVTLEL MAK L VD EE N A 482
PRK08951
PRK08951 malate synthase; Provisional
167-332
7.10e-27
malate synthase; Provisional
Pssm-ID: 181593 [Multi-domain]
Cd Length: 190
Bit Score: 108.19
E-value: 7.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 167 M A Y A R QFLD KAL PL E NGSH IESTN Y SIVDGA L AITLR D S SH TT L KN P E Q LIGYQ G EAQN PS V ILLK NN G L H I EL QI D H H H 246
Cdd:PRK08951 38 Q A K A K QFLD RLF PL A NGSH QDVSS Y VVYYQH L LAFFA D G SH SG L RQ P K Q FVAFN G HKSE PS A ILLK DS G S H V EL TF D R H G 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 247 PI G QA D K A GLK D VV LE AAL T TIMDCEDSVAA vdaedkvq VYKN W LG L MQ G nlvetfrk GDKMIDRTL Q A D RQY T GL DG QK 326
Cdd:PRK08951 118 GT G SR D L A NIE D IQ LE TCT T FSQEPTENRST -------- AMRH W IS L LK G -------- DESGRPAAD Q E D KEF T AK DG SD 181
....*.
gi 2049888662 327 LT LK GR 332
Cdd:PRK08951 182 YQ LK SC 187
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
603-658
3.51e-05
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 46.86
E-value: 3.51e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2049888662 603 L G Y VVR W I d Q G I GC sk VP d I N hi G LMED R AT LR IS SQHIAN W LH HGV CSKEQVQK V 658
Cdd:cd00727 403 L Q Y LAA W L - R G N GC -- VP - I Y -- N LMED A AT AE IS RAQLWQ W IR HGV RLLDDGRP V 452
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
605-665
2.25e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 41.24
E-value: 2.25e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 605 Y VVR W I d Q G I G C sk VP d I NH ig LMED R AT LR IS - SQ h IAN W L HHG V ------- CSK E Q V QKVM A K - M AK V 665
Cdd:COG2225 425 Y LEA W L - R G N G A -- VP - I YN -- LMED A AT AE IS r SQ - VWQ W I HHG A tlddgrk VTA E L V RQLL A E e L AK L 487
PLN02626
PLN02626 malate synthase
394-649
2.53e-03
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 40.91
E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 394 PKM HGPD E VAFA N TL F GMV E EALSL P KNTLKMGIMD E ERRTSANLKACIHAAKERVVFI N T G FL D RTGDEIH T s MQ A -- G 471
Cdd:PLN02626 218 PKM EHSR E ARLW N DV F EAA E KMAGI P RGSIRATVLI E TLPAVFQMEEILYELRDHSAGL N C G RW D YIFSFVK T - FR A hp D 296
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 472 VV LP K -- AAIKA Q PWISA Y E D RNVDI gla C gls HK aqig K G MW AM ------- P D K --------- M A MMMEQ K IAHPQS G A 533
Cdd:PLN02626 297 RL LP D rv QVGMT Q HFMKS Y V D LLIKT --- C --- HK ---- R G VH AM ggmaaqi P I K ddpaaneaa L A LVRKD K LREVRA G H 366
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049888662 534 NTA W VPS P TAAT L h AM hyhdv D VF S ------- L QQ SIAT R QIASL -- ES LL TP P lmpnpetl SKEDIQSE L EN N AQGILG 604
Cdd:PLN02626 367 DGT W AAH P GLIP L - AM ----- E VF D ghmptpn N QQ LHKR R DDVNV te AD LL QV P -------- RGVRTLEG L RL N TRVGIQ 432
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2049888662 605 Y VVR W I d Q G I G C sk VP DI N hig LMED R AT LR IS SQHIAN W LHH G V 649
Cdd:PLN02626 433 Y LAA W L - T G T G S -- VP LY N --- LMED A AT AE IS RVQNWQ W IKY G A 471
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
