|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-517 |
6.01e-169 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 485.88 E-value: 6.01e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 8 KLLFFVIATLFGIVLSVPSIFQTQGPKIILGLDLQGGLNLL------------LGVKTEEAIKTRYSSLASQINYYALDE 75
Cdd:PRK05812 2 KYLLILLVLLIGLLYALPNLRGALAPATPEWLPALGAKPMKlgldlrggvhflLEVDMDDALKKRLESLADDLRSLLREK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 76 QILLDGlnagedsVSFELLDSNEKVKVDAYLKTIpgldiaennlhytISFAETEIINLKNFAIEQAIGNIRNRLDQFGLS 155
Cdd:PRK05812 82 KIRYGG-------VEITFRDAEDRDKAIALLRKL-------------SSLTEAELKEITEEALEQAIEIIRNRVNELGVA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 156 EPSVAKQGDDAILVQLPGIKtqeEEQRALELISKGGHLQMMAVDearnarvssmteleaesygdvilpfvedenqkillk 235
Cdd:PRK05812 142 EPVIQRQGADRIVVELPGVQ---DTARAKEILGKTATLEFRLVP------------------------------------ 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 236 aiPILDGAMLTDARAAYDQNGQPVINFTLNAQGGKIFGDFSGKNVGNRMAIVLDGKVYSAPVIRERIGGGSGQISGGFSV 315
Cdd:PRK05812 183 --VILTGDDITDASASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISAPVIQSAITGGSAQITGNFTA 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 316 QQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVM 395
Cdd:PRK05812 261 EEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVL 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 396 ALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAI 475
Cdd:PRK05812 341 SLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPV 420
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 2084866097 476 KGFAITMSIGILASIITAIVGTHGVFRMFQNRIMKSGNYALW 517
Cdd:PRK05812 421 KGFAVTLGIGILTSMFTAITVTRALVNLLYGRRKRLKKLSIG 462
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
126-504 |
1.58e-154 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 448.02 E-value: 1.58e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 126 AETEIINLKNFAIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIKTQEeeqRALELISKGGHLQMMAVDEARNAR 205
Cdd:COG0342 56 DGDGIREVTEEALDQAIEILRNRVNELGVSEPVIQRQGDDRIVVELPGVQDPA---EAKELLGKTAKLEFRLVDDSADAQ 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 206 vssmtelEAESYGDVILPfvEDENQKILLKAIPILDGAMLTDARAAYD-QNGQPVINFTLNAQGGKIFGDFSGKNVGNRM 284
Cdd:COG0342 133 -------AAVPAGSELLP--CRDGQPYLLLGPVVLTGDDLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPL 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 285 AIVLDGKVYSAPVIRERIGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAIL 364
Cdd:COG0342 204 AIVLDGEVISAPVIQEPITGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 365 VVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENFIKSMEN 444
Cdd:COG0342 284 VALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEA 363
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 445 GYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGTHGVFRMF 504
Cdd:COG0342 364 GFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLL 423
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
111-497 |
1.88e-145 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 423.62 E-value: 1.88e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 111 GLDI---------AENNLHYTISFAETEIINLKNFAIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIktqEEEQ 181
Cdd:TIGR01129 2 GLDLrggarvlleVDMSTAVVLKLSEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGV---TDTS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 182 RALELISKGGHLQMMAVDEARNARVSSMTELEAEsyGDVILPFVEDENQKILLKAIPILDGAMLTDARAAYDQ-NGQPVI 260
Cdd:TIGR01129 79 RAKDILGGTATLEFRLVDDESTSPDDALAGNVPA--GSELLDSRSGDPKYYLLKKSPVLTGDHITDATSSVDQrSGQPVV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 261 NFTLNAQGGKIFGDFSGKNVGNRMAIVLDGKVYSAPVIRERIGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKR 340
Cdd:TIGR01129 157 SFSLDSEGARIFGDFTQANIGKRLAIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEER 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 341 SVGPSLGADSIKAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDA 420
Cdd:TIGR01129 237 TIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDA 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2084866097 421 NVIINERIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGT 497
Cdd:TIGR01129 317 NVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFT 393
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
132-521 |
1.74e-122 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 376.49 E-value: 1.74e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 132 NLKNFAIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIKTQEeeqRALELISkgghlqmmavdeaRNARVSSMTE 211
Cdd:PRK13024 55 KADREALDSTVEVLRNRIDGLGVSEPNIQREGNNRIRVELPGVQDPE---RARELLG-------------STAKLTFRDV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 212 LEAESYGDVILPFVEDENQKILLKAIPILDGAMLTDARAAYDQ--NGQPVINFTLNAQGGKIFGDFSGKNV-----GNRM 284
Cdd:PRK13024 119 TDPPPPGVGGPVVGPDEGKDTAVLNPVLLSGDDLTDAGAKFDQdqTNRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRI 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 285 AIVLDGKVYSAPVIRERIGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAIL 364
Cdd:PRK13024 199 AIVLDPKVISAPTVNQPINGGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFAL 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 365 VVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENFIKSMEN 444
Cdd:PRK13024 279 IFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKK 358
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 445 GYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGThgvfRMFQNRIMKSG-NYALWFGYR 521
Cdd:PRK13024 359 GFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLT----RLLLELLVKRGdKKPFLFGVK 432
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
137-507 |
2.33e-103 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 329.37 E-value: 2.33e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 137 AIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIktqEEEQRALELISKGGHL------QMMAVDEARNARVSSMT 210
Cdd:PRK14726 162 ALTQSIEVVRRRVAELGTTEPLIRRQGDDRIVVQVPGL---VDPQRLKNLLNQPAKLsfrlvdSSMPAQEALNGRPPATS 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 211 ELeAESYGDVILPFvedenqkiLLKAIPILDGAMLTDARAAYD-QNGQPVINFTLNAQGGKIFGDFSGKNVGNRMAIVLD 289
Cdd:PRK14726 239 EV-LYSLDDPPVPY--------LVERRAFVSGENLVDAQPVFDpQTNEPVVTFRLDAEGTQRFAQATQQNVGKHFAIVLD 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 290 GKVYSAPVIRERIGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVVFM 369
Cdd:PRK14726 310 GQVISAPVIDEAITGGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALM 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 370 VFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENFIKSMENGYANA 449
Cdd:PRK14726 390 IGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRA 469
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 450 SRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGTHGVFRMFQNR 507
Cdd:PRK14726 470 LATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRR 527
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
51-498 |
2.69e-78 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 256.92 E-value: 2.69e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 51 VKTEEAIKTRYSSLASQINYYALDEQIllDGL---NAGEDSVSFELLDSNEKVKVDAYLKT-IPGLDI-AENNLHYTISF 125
Cdd:PRK12933 142 VDVDPVYQEQRDALVDSVRQFLREQRI--RGVsvrLDDSDQLAVTTPDNDARSAVRQFIQQnYPGWQVtNSDDRGLQLKL 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 126 AETEIINLKNFAIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIktQEEEQrALELISKGGHLQMMAVDEArnAR 205
Cdd:PRK12933 220 SQQEKTKFRNLTVQQNLQIMRSRIEELGITEALVQRQGEHRIRIELPGV--QDPAA-AKNVIGATASLAFYEVKES--GS 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 206 VSSMTeleaesygdvilpfVEDEN-QKILLKAIPILDGAMLTDARAAYDQNGQPVINFTLNAQGGKIFGDFSGKNVGNRM 284
Cdd:PRK12933 295 VNAKV--------------LKDKNgRPVYVARRPVLGGEHIVDARASLGEMGMAEVNISLDRAGGKKMSDFSRDNIGKPM 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 285 A-------------IVLDGKVYSAPVIRERIGGGSGQISGGfSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSI 351
Cdd:PRK12933 361 AtsyseysrdeqgkTKQSEEVISVATIQSQLGDRFRITGAG-SYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENI 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 352 KAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALF-GATLTLPGMAGIILTVGMAVDANVIINERIRE 430
Cdd:PRK12933 440 ENGFAALALGMGITLLFMALWYRRLGWVANVALIANMVCLFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKD 519
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 431 GFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGTH 498
Cdd:PRK12933 520 KLKEGRSFAQAIDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASR 587
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
129-497 |
3.06e-65 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 225.65 E-value: 3.06e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 129 EIINLKNFAIEQAIGNIRNRLDQFGLSEPSVAKQGDDAILVQLPGIKtqeEEQRALELISKGGHLQMMAVDEARNARVSS 208
Cdd:PRK13023 60 QVQNAGKTDLETTANIMRQRLEELGYGNPVVEGEGRNQIRVEVPGLY---DAQLLKDILTIRGNLSFRAMDDTMSPDDAI 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 209 MTELEAESygDVILPFvEDENQKILLKAIPILDGAMLTDARAAY-DQNGQPVINFTLNAQGGKIFGDFSGKNVGNRMAIV 287
Cdd:PRK13023 137 RGTPPADS--EIVYSF-DDPPVGYLLKKTPILTGHDITDAKASIsADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIV 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 288 LDGKVYSAPVIRERIGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVV 367
Cdd:PRK13023 214 VDNQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 368 FMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENFIKSMENGYA 447
Cdd:PRK13023 294 FMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFY 373
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2084866097 448 NASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGT 497
Cdd:PRK13023 374 RALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFT 423
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
250-507 |
1.69e-50 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 186.60 E-value: 1.69e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 250 AAYDQNGqpvINFTLNAQggkifgdFSGkNVGNRMAIVLDGKVYSAPVIRErIGGGSGQISGGFSVQQASDIAIALRSGA 329
Cdd:PRK12911 819 SAYCQEG---VSGTKNGQ-------FSG-GRGWRMAVVLDGYVVSDPVLNV-PLKDHASVSGKFSHREVHRLATDLKSGA 886
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 330 LPAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAG 409
Cdd:PRK12911 887 MSFVPEVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAG 966
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 410 IILTVGMAVDANVIINERIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILAS 489
Cdd:PRK12911 967 IVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSS 1046
|
250
....*....|....*...
gi 2084866097 490 IITAIVGTHGVFRMFQNR 507
Cdd:PRK12911 1047 MFTALFMTKFFFMIWMNK 1064
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
264-494 |
1.67e-48 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 165.89 E-value: 1.67e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 264 LNAQGGKIFGDFsGKNVGNRMAIVLDGKVYSAPVIRerigggsgqisggfsvqqasdiaialrsgalpapitllekrSVG 343
Cdd:TIGR00916 1 LDEEGAKIFADF-AANIGKPAIVLDNAKVISAPVVG-----------------------------------------TVG 38
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 344 PSLGADSIKAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVN-ILLVIAVMALFGATLTLPGMAGIILTVGMAVDANV 422
Cdd:TIGR00916 39 PTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTV 118
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2084866097 423 IINERIREGFRAKE--NFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAI 494
Cdd:TIGR00916 119 VIFDRIREELRKYKgrTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
145-487 |
2.98e-26 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 110.73 E-value: 2.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 145 IRNRLDQFGLSEPSVAKQGDDAILVQLPGiktqEEEQRALELISKGGHLQMMAVDEARNaRVSSMTELEAESYGdvilpf 224
Cdd:PRK08343 72 LESRLNALGLKDIKVYPVGDQYIVVEVPG----VDADTAKEIIEKQGVFEARIQTPGNN-NETVLTGDDIESVG------ 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 225 vedenqkillkaIPILDgamltdaraayDQNGQPVINFTLNAQGGKIFGD------FSGKNVGNRMAIVLDGKVYSAPVI 298
Cdd:PRK08343 141 ------------SPSQD-----------PSGGAWGVPFTLSEDGAEKFAEvakgkgATDDPSGHPLDMYLDGELIYAAPL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 299 RER----------IGGGSGQISGGFSVQQASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALItGAILVVVF 368
Cdd:PRK08343 198 SPDlasglasgpvVITVGSTGTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGSLIAGL-LALLAVAL 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 369 MVFY-YG---IAGFIADIAMV-VNILLVIAvmALFGATLTLPGMAGIILTVGMAVDANVII-NERIREGFRAKENFIKSm 442
Cdd:PRK08343 277 VVFLrYReprIALPMVITSLSeVIIILGFA--ALIGWQLDLASIAGIIAVIGTGVDDLIIItDEVLHEGKVPSRKVFLS- 353
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2084866097 443 engyaNASRA---IFDSNLTSLIA-AVLLYMcGTGAIKGFAITMSIGIL 487
Cdd:PRK08343 354 -----RIKRAffiIFAAAATTIAAmSPLAVM-GLGDLKGFAITTILGVL 396
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
314-497 |
4.64e-15 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 75.86 E-value: 4.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 314 SVQQASDIAIALRSGAlpAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVVFMVFY----YGIAgfiADIAMVVNIL 389
Cdd:COG0341 97 SAEEVEKVRAALKEAF--GDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRfewrFAVG---AVVALLHDVL 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 390 LVIAVMALFGATLTLPGMAGIiLTV-GMAVDANVIINERIREGFRA--KENFIKSMengyaNAS------RAIFDSnLTS 460
Cdd:COG0341 172 ITLGIFSLFGLEFDLTFIAAL-LTIiGYSLNDTVVVFDRIRENLRKyrKMTLAEII-----NLSinqtlsRTINTS-LTT 244
|
170 180 190
....*....|....*....|....*....|....*..
gi 2084866097 461 LIAAVLLYMCGTGAIKGFAITMSIGIlasiitaIVGT 497
Cdd:COG0341 245 LLVVLALLFFGGETLRDFALALLIGI-------IVGT 274
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
340-518 |
1.33e-14 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 77.13 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 340 RSVGPSLGADSIKAAMIALITGAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVD 419
Cdd:NF037998 433 SEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLE 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 420 ANVIINERI-REGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVgth 498
Cdd:NF037998 513 SCSLLFEAFkKHLYKNKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVII--- 589
|
170 180
....*....|....*....|...
gi 2084866097 499 gVFRMFQNRIMKSG---NYALWF 518
Cdd:NF037998 590 -VARLMIWLTIKLQwfkKYPWLL 611
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
341-497 |
1.35e-13 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 70.38 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 341 SVGPSLGADSIKAAMIALITGAILVVVFMVF----YYGIAGFIAdiaMVVNILLVIAVMALFGATLTLPGMAGIILTVGM 416
Cdd:TIGR00966 87 AVGPSVGGELARKAVLALLAALVLILIYITVrfewRFALGAIVA---LVHDVIITVGVYSLFGIEVNLTTVAALLTIIGY 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 417 AVDANVIINERIRegfrakENFIKSMENGYANA---------SRAIFDSnLTSLIAAVLLYMCGTGAIKGFAITMSIGIl 487
Cdd:TIGR00966 164 SINDTVVVFDRIR------ENLRKYTRKTFTEVinlsinqtlSRTINTS-LTTLLAVLALYVFGGGVIKDFSLALLVGV- 235
|
170
....*....|
gi 2084866097 488 asiitaIVGT 497
Cdd:TIGR00966 236 ------IVGT 239
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
341-494 |
1.78e-13 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 68.79 E-value: 1.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 341 SVGPSLGADSIKAAMIALIT--GAILVVVFMVF--YYGIAgfiADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGM 416
Cdd:pfam02355 20 TVGPTVGSELARKAVLALLFalLLILIYVGLRFewRFALG---AIIALAHDVIITVGVFSLFGIEVDLATVAALLTIIGY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 417 AVDANVIINERIREGFRAKENF-IKSMENGYANA--SRAIFDSnLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITA 493
Cdd:pfam02355 97 SVNDTVVVFDRVRENLRKKTRAtLNEIMNLSINQtlTRTINTS-LTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYSS 175
|
.
gi 2084866097 494 I 494
Cdd:pfam02355 176 I 176
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
353-493 |
1.87e-11 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 66.80 E-value: 1.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 353 AAMIALITGAILVVVFMVFYYGI-AGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIIneriREG 431
Cdd:COG4258 641 ALWLLLLALLLILLLLLLRLRSLrRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFF----TEG 716
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2084866097 432 FRAKENFIKSMengyanasRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITA 493
Cdd:COG4258 717 LLDKGELARTL--------LSILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLA 770
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
341-497 |
2.66e-11 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 66.02 E-value: 2.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 341 SVGPSLGADSIKAAMIALITGAILVVVFMVF----YYGIAGFIAdiaMVVNILLVIAVMALFGATLTLPGMAGIILTVGM 416
Cdd:PRK13024 566 TVGPTVGKELARNAIIAVLIALIGILLYILIrfewTFSLGAILA---LLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGY 642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 417 AVDANVIINERIREGFRAKEnfIKSMENgYANAS------RAIFDSnLTSLIAAVLLYMCGTGAIKGFAITMSIGIlasi 490
Cdd:PRK13024 643 SINDTVVVFDRIRENLRLYK--KKDLRE-IVNKSinqtlsRTINTS-LTTLLVLLALLIFGGSSLRNFSLALLVGL---- 714
|
....*..
gi 2084866097 491 itaIVGT 497
Cdd:PRK13024 715 ---IVGT 718
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
316-497 |
1.47e-10 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 62.18 E-value: 1.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 316 QQASDIAIALrsGALPAPITLLEKRSVGPSLGADSIKAAMIALITGAILVVVFMV--FYYGIAGFiADIAMVVNILLVIA 393
Cdd:PRK13021 92 QSNVDIQQAL--APLGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSyrFEWRLASG-ALFALVHDVIFVLA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 394 VMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKENF-IKSMENG--YANASRAIFDSNlTSLIAAVLLYMC 470
Cdd:PRK13021 169 FFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLaIQEINNQaiVATFSRTMVTSG-TTLMTVGALWIM 247
|
170 180
....*....|....*....|....*...
gi 2084866097 471 GTGAIKGFAITMSIGILASIITAI-VGT 497
Cdd:PRK13021 248 GGGPLEGFSIAMFIGILTGTFSSIsVGT 275
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
348-495 |
3.52e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 62.57 E-value: 3.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 348 ADSIKAAMIALITGAILVVVFMVFYY---GIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVII 424
Cdd:COG1033 213 AEAIQSDLAIFFPLALLLILLLLFLFfrsLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHL 292
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2084866097 425 NERIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIV 495
Cdd:COG1033 293 LNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLT 363
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
351-495 |
5.98e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.80 E-value: 5.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 351 IKAAMIALITGAILVVVFMVFYYG--IAGFIADIAMVVNILLVIAVMALFGATLTlPGMAGII-LTVGMAVDANVIINER 427
Cdd:COG1033 604 IESQIRSLLLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLGIPLN-IATAVVAsIALGIGVDYTIHFLSR 682
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 428 IREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIV 495
Cdd:COG1033 683 YREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALL 750
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
349-494 |
8.19e-09 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 58.58 E-value: 8.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 349 DSIKAAMIALITGAILVVVFM-VFYYGI-AGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVD-ANVI-- 423
Cdd:COG0841 328 ASIEEVVKTLLEAILLVVLVVfLFLRSWrATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVVDdAIVVve 407
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2084866097 424 -INERIREGFRAKENFIKSMEngyaNASRAIFDSNLTslIAAV---LLYMCG-TGAI-KGFAITMSIGILASIITAI 494
Cdd:COG0841 408 nIERHMEEGLSPLEAAIKGAR----EVAGAVIASTLT--LVAVflpLAFMGGiTGQLfRQFALTVAIALLISLFVAL 478
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
363-497 |
1.07e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.84 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 363 ILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRA---KENFI 439
Cdd:TIGR00921 580 VLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEhgpKEAIT 659
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 440 KSMEngyaNASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIVGT 497
Cdd:TIGR00921 660 HTME----RTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVF 713
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
359-496 |
1.72e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.07 E-value: 1.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 359 ITGAILVVVFMVFYYG-IAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERIREGFRAKEN 437
Cdd:TIGR00921 201 ISGILVVLVLLLDFKRwWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRA 280
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 438 FIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIG-ILASIITAIVG 496
Cdd:TIGR00921 281 KGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGlITAYLLTLLVL 340
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
340-492 |
1.95e-07 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 52.63 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 340 RSVGPSLGADSIKAAMIALITGAIL--VVVFMVFyygiAGFIADIAMVV----NILLVIAVMALFGATLTLPGMAGIILT 413
Cdd:PRK08578 122 KQIGPTFGSQFQEQALKAVGFAFIGmaVVVFLIF----RTPVPSLAVILsafsDIIIALALMNLFGIELSLATVAALLML 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 414 VGMAVDANVIINERI-REGFRAKENFIKSMENGyanasraiFDSNLTSLIAAVLLY----MCGTGAIKGFAITMSIGILA 488
Cdd:PRK08578 198 IGYSVDSDILLTTRVlKRRGTFDESIKRAMRTG--------ITMTLTTIAAMAVLYivstIPQAEVLANIAAVLIFGLLA 269
|
....
gi 2084866097 489 SIIT 492
Cdd:PRK08578 270 DLMN 273
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
318-494 |
2.16e-07 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 53.57 E-value: 2.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 318 ASDIAIALRSGALPAPITLLEKRSVGPSLGADSIKAAMIALITG--AILVVVFMVFYYGIA-GFIadIAMVVNILLVIAV 394
Cdd:PRK14726 638 AEQSAVTLVRGELEDDYDFRRVEVVGPAVSGELTMAATLGVLAAlaAILIYIWIRFEWQFAvGAI--IATLHDVILTLGL 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 395 MALFGATLTLPGMAGIILTVGMAVDANVIINERIREGF-RAKENFIKSMENGYANA--SRAIFDSnLTSLIAAVLLYMCG 471
Cdd:PRK14726 716 FVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLrRYKKMPLPILIDASINQtlSRTVLTS-ATTLLALLALYLFG 794
|
170 180
....*....|....*....|...
gi 2084866097 472 TGAIKGFAITMSIGILASIITAI 494
Cdd:PRK14726 795 GEVIRSFTFAMLFGVAVGTFSSI 817
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
346-494 |
2.04e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 50.53 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 346 LGADSIKAAMIALITGAILVVVFMVFYYG--IAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTV---GMAVD- 419
Cdd:COG2409 163 LNEAFEEDLGRAELITLPVALVVLLLVFRslVAALLPLLTAGLAVGVALGLLALLAAFTDVSSFAPNLLTMlglGVGIDy 242
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2084866097 420 ANVIINeRIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAI 494
Cdd:COG2409 243 ALFLVS-RYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAAL 316
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
350-494 |
2.06e-06 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 50.76 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 350 SIKAAMIALITGAILVVVFMVFYYG--IAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINER 427
Cdd:pfam00873 329 SIEEVVKTLLEAIVLVILVMFLFLQnwRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVEN 408
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2084866097 428 IREGfrAKENFIKSMENGYANASRAIFDSNLTSLIAAV----LLYMCG-TGAI-KGFAITMSIGILASIITAI 494
Cdd:pfam00873 409 IERV--LEENGLKPLEAAYKSMGEIGGALVAIALVLSAvflpILFLGGlTGRIfRQFAITIVLAILLSVLVAL 479
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
313-497 |
4.49e-06 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 49.52 E-value: 4.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 313 FSVQQASDIAIALRSGA--------LPAPITLLEK------RSVGPSLGADSIKAAMIALITGAI--LVVVFMVFYYGIA 376
Cdd:PRK15127 281 FNGQPASGLGIKLATGAnaldtaaaIRAELAKMEPffpsglKIVYPYDTTPFVKISIHEVVKTLVeaIILVFLVMYLFLQ 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 377 GF----IADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINERI-----REGFRAKENFIKSMEN--- 444
Cdd:PRK15127 361 NFratlIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVervmaEEGLPPKEATRKSMGQiqg 440
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2084866097 445 ---GYANASRAIFdsnltsliAAVLLYMCGTGAI-KGFAITMSIGILASIITAIVGT 497
Cdd:PRK15127 441 alvGIAMVLSAVF--------VPMAFFGGSTGAIyRQFSITIVSAMALSVLVALILT 489
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
346-501 |
1.81e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 47.35 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 346 LGADSIKAAMIALITGAILVVVFMvfYYGIAGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVD--ANVI 423
Cdd:pfam02460 637 ILPSTIQNIVITLICMFIVCFLFI--PNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDfsAHIA 714
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2084866097 424 INERIREGFRAKENFIKSMEN-GYanasrAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIItaivgtHGVF 501
Cdd:pfam02460 715 YHFVRSRGDTPAERVVDALEAlGW-----PVFQGGLSTILGVLVLLFVPSYMVVVFFKTVFLVVAIGLL------HGLF 782
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
350-497 |
2.18e-05 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 47.42 E-value: 2.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 350 SIKAAMIALITGAILVVVFM-VFYYGI-AGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINER 427
Cdd:TIGR00915 336 SIEEVVHTLIEAIVLVFLVMyLFLQNFrATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLVDDAIVVVEN 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 428 IR-----EGFRAKENFIKSMENgYANASRAIfdsnlTSLIAAVLLYMC----GTGAI-KGFAITMSIGILASIITAIVGT 497
Cdd:TIGR00915 416 VErvmaeEGLPPKEATRKSMGQ-IQGALVGI-----AMVLSAVFVPMAffggSTGAIyRQFSITIVSAMALSVLVALILT 489
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
342-494 |
1.40e-04 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 44.61 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 342 VGPSLGADSIKAAMIALITG--AILVVVFMVFYYGIAgFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVD 419
Cdd:PRK13023 568 VGPTVSEQLSRAGVLAVILSliGIFIYVWFRFRWQLA-LGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLN 646
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 420 ANVIINERIREGFRA-KENFIKSMENGYANA--SRAIFDSNLTsLIAAVLLYMCGTGAIKGFAITMSIGILASIITAI 494
Cdd:PRK13023 647 DTVVIYDRVRENLRRyKSAPLPAIIDASINQtlSRTLLTSFVT-FLAHVPLYAFGGSEIRMFALALSVGIIVASYSSI 723
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
342-497 |
2.26e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 43.43 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 342 VGPS-LGADSIKAA----MIALITGAILVVVFMVFYYG--IAGFI----ADIAMVV--NILLVIAVMALFGATLTLPGMA 408
Cdd:pfam03176 127 TGPAaTVADLRDAGdrdlGLIEAVTLVVIFIILLIVYRsvVAALLplltVGLSLGAaqGLVAILAHILGIGLSTFALNLL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 409 GIILtVGMAVDANVIINERIREGFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILa 488
Cdd:pfam03176 207 VVLL-IAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVL- 284
|
....*....
gi 2084866097 489 sIITAIVGT 497
Cdd:pfam03176 285 -VDVLAALT 292
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
351-495 |
2.11e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 40.75 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 351 IKAAMIALItgAILVVVFMVFYYGIAGFIADIAMVVNILLVIAVMALFGATLTLpgmAGII---LTVGMAVDANVIINER 427
Cdd:TIGR03480 715 LQAFIYALV--AITVLLLLTLRRVRDVLLVLAPLLLAGLLTVAAMVLLGIPFNF---ANIIalpLLLGLGVDFGIYMVHR 789
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2084866097 428 IREGfRAKENFIKSMEngyanaSRAIFDSNLTSLIAAVLLYMCGTGAIKGFAITMSIGILASIITAIV 495
Cdd:TIGR03480 790 WRNG-VDSGNLLQSST------ARAVFFSALTTATAFGSLAVSSHPGTASMGILLSLGLGLTLLCTLI 850
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
357-494 |
2.88e-03 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 40.40 E-value: 2.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 357 ALITGAILV-VVFMVFYYGI-AGFIADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAVDANVIINE----RIRE 430
Cdd:COG3696 340 NLLEGALLViLVLFLFLGNLrAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVEnilrRLEE 419
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2084866097 431 gfRAKENFIKSMENGYANAS----RAIFDSnlTSLIAAV---LLYMCGT-GAIkgF---AITMSIGILASIITAI 494
Cdd:COG3696 420 --NRAAGTPRERLEVVLEAArevrRPIFFA--TLIIILVflpIFTLEGVeGKL--FrpmALTVIFALLGALLLSL 488
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
362-497 |
7.44e-03 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 39.04 E-value: 7.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 362 AILVVvFMVFYYGIAGF----IADIAMVVNILLVIAVMALFGATLTLPGMAGIILTVGMAV-DANVIIN--ERI--REGF 432
Cdd:PRK10555 347 AIALV-FLVMYLFLQNFratlIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIGLLVdDAIVVVEnvERImsEEGL 425
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2084866097 433 RAKENFIKSMenGYANASRAIFDSNLTSLIAAVLLYMCGTGAI-KGFAITMSIGILASIITAIVGT 497
Cdd:PRK10555 426 TPREATRKSM--GQIQGALVGIAMVLSAVFVPMAFFGGTTGAIyRQFSITIVSAMVLSVLVAMILT 489
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
347-467 |
9.52e-03 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 38.93 E-value: 9.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2084866097 347 GADSIKAAMIAL--ITGAI------LVVVF--MVFYYGIAG-FIADIAMVVNILLVI-AVMALfgaTLTlPGMAGIILTV 414
Cdd:COG0841 416 GLSPLEAAIKGAreVAGAViastltLVAVFlpLAFMGGITGqLFRQFALTVAIALLIsLFVAL---TLT-PALCARLLKP 491
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2084866097 415 GMAVDANVIineriregFRAKENFIKSMENGYANASRAIFDSNLTSLIAAVLL 467
Cdd:COG0841 492 HPKGKKGRF--------FRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALAL 536
|
|
| |
