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Conserved domains on  [gi|2151987079|ref|WP_229038580|]
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MULTISPECIES: IS3 family transposase [Gammaproteobacteria]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
3-247 4.91e-67

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 209.62  E-value: 4.91e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079   3 RRSWYYRSVKAAPKLQEHLVTPIKNMIEENPSFGYRTVAALL---GF--NKNTVQRIFQLKGWQVRKRPVGFR------- 70
Cdd:COG2801    55 RRRRLRRPRSYRADEDAELLERIKEIFAESPRYGYRRITAELrreGIavNRKRVRRLMRELGLQARRRRKKKYttysghg 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  71 -PRIQALPSVASAPNQRWATDLCRIWAGrDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARfgslgRVAS 149
Cdd:COG2801   135 gPIAPNLLFTATAPNQVWVTDITYIPTA-EGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERR-----GPPK 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 150 PFLLRSDNGLVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKR 229
Cdd:COG2801   209 PLILHSDNGSQYTSKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHER 288

                         250
                  ....*....|....*...
gi 2151987079 230 PHQALKMKTPAQAYAEAA 247
Cdd:COG2801   289 PHSSLGYLTPAEYEKQLA 306
 
Name Accession Description Interval E-value
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
3-247 4.91e-67

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 209.62  E-value: 4.91e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079   3 RRSWYYRSVKAAPKLQEHLVTPIKNMIEENPSFGYRTVAALL---GF--NKNTVQRIFQLKGWQVRKRPVGFR------- 70
Cdd:COG2801    55 RRRRLRRPRSYRADEDAELLERIKEIFAESPRYGYRRITAELrreGIavNRKRVRRLMRELGLQARRRRKKKYttysghg 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  71 -PRIQALPSVASAPNQRWATDLCRIWAGrDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARfgslgRVAS 149
Cdd:COG2801   135 gPIAPNLLFTATAPNQVWVTDITYIPTA-EGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERR-----GPPK 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 150 PFLLRSDNGLVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKR 229
Cdd:COG2801   209 PLILHSDNGSQYTSKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHER 288

                         250
                  ....*....|....*...
gi 2151987079 230 PHQALKMKTPAQAYAEAA 247
Cdd:COG2801   289 PHSSLGYLTPAEYEKQLA 306
transpos_IS3 NF033516
IS3 family transposase;
4-243 3.01e-59

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 191.24  E-value: 3.01e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079   4 RSWYYRSVKAAPKLQEHLVTPIKNMIEENP-SFGYRTVAALL---GF--NKNTVQRIFQ---LKGWQVRKRPVGFRPRIQ 74
Cdd:NF033516  118 YYWRKRPPSRRAPDDAELRARIREIFEESRgRYGYRRITALLrreGIrvNHKRVYRLMRelgLLARRRRKRRPYTTDSGH 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  75 ALPSV---------ASAPNQRWATDLCRIWAGrDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARFGSLG 145
Cdd:NF033516  198 VHPVApnllnrqftATRPNQVWVTDITYIRTA-EGWLYLAVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEG 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 146 RVaspflLRSDNGLVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFY 225
Cdd:NF033516  277 LI-----LHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFY 351

                         250
                  ....*....|....*...
gi 2151987079 226 NQKRPHQALKMKTPAQAY 243
Cdd:NF033516  352 NHERPHSSLGYLTPAEFE 369
transpos_IS481 NF033577
IS481 family transposase; null
 49-243 5.62e-31

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 115.77  E-value: 5.62e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  49 NTVQRIFQ---LKGWQVRKRPVGFRPRIQAlpsvaSAPNQRWATDLCRIWAGRD-GWCSLALVIDCHTRellgWHLSRSG 124
Cdd:NF033577   95 STVHRILRrhgLSRLRALDRKTGKVKRYER-----AHPGELWHIDIKKLGRIPDvGRLYLHTAIDDHSR----FAYAELY 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 125 KSKTAEAALE--QALIARFG-SLGRVaspfllRSDNGLVFTSR--NYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLK 199
Cdd:NF033577  166 PDETAETAADflRRAFAEHGiPIRRV------LTDNGSEFRSRahGFELALAELGIEHRRTRPYHPQTNGKVERFHRTLK 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2151987079 200 EQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTPAQAY 243
Cdd:NF033577  240 DEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAERF 283
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 79-242 1.17e-30

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 114.58  E-value: 1.17e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  79 VASAPNQRWATDLCRIWAGRdGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARfgslgRVASPFLLRSDNG 158
Cdd:PHA02517  105 VATRPNQLWVADFTYVSTWQ-GWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQALWAR-----GRPGGLIHHSDKG 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 159 LVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKT 238
Cdd:PHA02517  179 SQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLEWVAWYNNRRLHERLGYTP 258


                  ....
gi 2151987079 239 PAQA 242
Cdd:PHA02517  259 PAEA 262
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 83-185 2.33e-21

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 85.44  E-value: 2.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  83 PNQRWATDLCRIW-AGRDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQAlIARFGSLGRVaspflLRSDNGLVF 161
Cdd:pfam00665   1 PNQLWQGDFTYIRiPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERA-IAFRGGVPLI-----IHSDNGSEY 74

                          90       100
                  ....*....|....*....|....
gi 2151987079 162 TSRNYTALVKSYGLQQEFITPYTP 185
Cdd:pfam00665  75 TSKAFREFLKDLGIKPSFSRPGNP 98
transpos_IS21 NF033546
IS21 family transposase;
126-245 1.10e-05

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 45.66  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 126 SKTAEAaLEQALIARFGSLGRVasPFLLRSDN------------GLVFTSRnYTALVKSYGLQQEFITPYTPEQNGMVER 193
Cdd:NF033546  158 SESQED-LLDGHQRAFEFFGGV--PREIVYDNlktavdkrdryeEPRLNPR-FAAFAAHYGFEPRPCRPYRPQEKGKVER 233

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2151987079 194 VIRTLKEQC--AHRQRFETLQHASRVIGDWIQFYNQKRPHQALKmKTPAQAYAE 245
Cdd:NF033546  234 AVGYVRRWFlrLRGRRFESLAELNAALAEWLAELANQRPHGTTG-GSPAERFEE 286
transpos_IS630 NF033545
IS630 family transposase;
179-223 5.54e-04

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 40.32  E-value: 5.54e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2151987079 179 FITPYTPEQNgMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQ 223
Cdd:NF033545  254 YLPPYSPWLN-PIERVWAVLKRRLLRNRAFRSVDELREAIDAFLN 297
 
Name Accession Description Interval E-value
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
3-247 4.91e-67

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 209.62  E-value: 4.91e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079   3 RRSWYYRSVKAAPKLQEHLVTPIKNMIEENPSFGYRTVAALL---GF--NKNTVQRIFQLKGWQVRKRPVGFR------- 70
Cdd:COG2801    55 RRRRLRRPRSYRADEDAELLERIKEIFAESPRYGYRRITAELrreGIavNRKRVRRLMRELGLQARRRRKKKYttysghg 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  71 -PRIQALPSVASAPNQRWATDLCRIWAGrDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARfgslgRVAS 149
Cdd:COG2801   135 gPIAPNLLFTATAPNQVWVTDITYIPTA-EGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERR-----GPPK 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 150 PFLLRSDNGLVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKR 229
Cdd:COG2801   209 PLILHSDNGSQYTSKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIEFYNHER 288

                         250
                  ....*....|....*...
gi 2151987079 230 PHQALKMKTPAQAYAEAA 247
Cdd:COG2801   289 PHSSLGYLTPAEYEKQLA 306
transpos_IS3 NF033516
IS3 family transposase;
4-243 3.01e-59

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 191.24  E-value: 3.01e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079   4 RSWYYRSVKAAPKLQEHLVTPIKNMIEENP-SFGYRTVAALL---GF--NKNTVQRIFQ---LKGWQVRKRPVGFRPRIQ 74
Cdd:NF033516  118 YYWRKRPPSRRAPDDAELRARIREIFEESRgRYGYRRITALLrreGIrvNHKRVYRLMRelgLLARRRRKRRPYTTDSGH 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  75 ALPSV---------ASAPNQRWATDLCRIWAGrDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARFGSLG 145
Cdd:NF033516  198 VHPVApnllnrqftATRPNQVWVTDITYIRTA-EGWLYLAVVLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEG 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 146 RVaspflLRSDNGLVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFY 225
Cdd:NF033516  277 LI-----LHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFY 351

                         250
                  ....*....|....*...
gi 2151987079 226 NQKRPHQALKMKTPAQAY 243
Cdd:NF033516  352 NHERPHSSLGYLTPAEFE 369
transpos_IS481 NF033577
IS481 family transposase; null
 49-243 5.62e-31

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 115.77  E-value: 5.62e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  49 NTVQRIFQ---LKGWQVRKRPVGFRPRIQAlpsvaSAPNQRWATDLCRIWAGRD-GWCSLALVIDCHTRellgWHLSRSG 124
Cdd:NF033577   95 STVHRILRrhgLSRLRALDRKTGKVKRYER-----AHPGELWHIDIKKLGRIPDvGRLYLHTAIDDHSR----FAYAELY 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 125 KSKTAEAALE--QALIARFG-SLGRVaspfllRSDNGLVFTSR--NYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLK 199
Cdd:NF033577  166 PDETAETAADflRRAFAEHGiPIRRV------LTDNGSEFRSRahGFELALAELGIEHRRTRPYHPQTNGKVERFHRTLK 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2151987079 200 EQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTPAQAY 243
Cdd:NF033577  240 DEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAERF 283
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 79-242 1.17e-30

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 114.58  E-value: 1.17e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  79 VASAPNQRWATDLCRIWAGRdGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQALIARfgslgRVASPFLLRSDNG 158
Cdd:PHA02517  105 VATRPNQLWVADFTYVSTWQ-GWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQALWAR-----GRPGGLIHHSDKG 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 159 LVFTSRNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKT 238
Cdd:PHA02517  179 SQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLEWVAWYNNRRLHERLGYTP 258


                  ....
gi 2151987079 239 PAQA 242
Cdd:PHA02517  259 PAEA 262
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 83-185 2.33e-21

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 85.44  E-value: 2.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  83 PNQRWATDLCRIW-AGRDGWCSLALVIDCHTRELLGWHLSRSGKSKTAEAALEQAlIARFGSLGRVaspflLRSDNGLVF 161
Cdd:pfam00665   1 PNQLWQGDFTYIRiPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERA-IAFRGGVPLI-----IHSDNGSEY 74

                          90       100
                  ....*....|....*....|....
gi 2151987079 162 TSRNYTALVKSYGLQQEFITPYTP 185
Cdd:pfam00665  75 TSKAFREFLKDLGIKPSFSRPGNP 98
rve_3 pfam13683
Integrase core domain;
173-239 3.77e-21

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 83.80  E-value: 3.77e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2151987079 173 YGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTP 239
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 25-247 5.83e-14

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 69.38  E-value: 5.83e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  25 IKNMIEENPSFGYRTVAALL----------GFNKNTVQRIFQLKGWQVRKRP-VGFRPRIQALPSVASAPNQRWATDLCR 93
Cdd:PRK14702   17 IHHVIGELPTYGYRRVWALLrrqaeldgmpAINAKRVYRLMRQNALLLERKPaVPPSKRAHTGRVAVKESNQRWCSDGFE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  94 IWAGRDGWCSLALVIDCHTRELLGWHLSRSG-KSKTAEAALEQALIARFGSlGRVASPFLLRSDNGLVFTSRNYTALVKS 172
Cdd:PRK14702   97 FCCDNGERLRVTFALDCCDREALHWAVTTGGfNSETVQDVMLGAVERRFGN-DLPSSPVEWLTDNGSCYRANETRQFARM 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2151987079 173 YGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTPAQAYAEAA 247
Cdd:PRK14702  176 LGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRA 250
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 25-247 5.86e-14

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 69.74  E-value: 5.86e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  25 IKNMIEENPSFGYRTVAALL----------GFNKNTVQRIFQLKGWQVRKRP-VGFRPRIQALPSVASAPNQRWATDLCR 93
Cdd:PRK09409   56 IHHVIGELPTYGYRRVWALLrrqaeldgmpAINAKRVYRIMRQNALLLERKPaVPPSKRAHTGRVAVKESNQRWCSDGFE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079  94 IWAGRDGWCSLALVIDCHTRELLGWHLSRSG-KSKTAEAALEQALIARFGSlGRVASPFLLRSDNGLVFTSRNYTALVKS 172
Cdd:PRK09409  136 FCCDNGERLRVTFALDCCDREALHWAVTTGGfNSETVQDVMLGAVERRFGN-DLPSSPVEWLTDNGSCYRANETRQFARM 214

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2151987079 173 YGLQQEFITPYTPEQNGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTPAQAYAEAA 247
Cdd:PRK09409  215 LGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRA 289
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
125-245 8.11e-13

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 66.83  E-value: 8.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 125 KSKTAEAAlEQALIARFGSLGRvaspFLLRS---DNGLVFTsrNYTALVKSYGLQQEFITPYTPEQNGMVERVIRTLKEQ 201
Cdd:COG2826   206 PDKTAESV-ADALIRLLRKLPA----FLRKSittDNGKEFA--DHKEIEAALGIKVYFADPYSPWQRGTNENTNGLLRQY 278

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2151987079 202 CAHRQRFETLQHAsrVIGDWIQFYNQkRPHQALKMKTPAQAYAE 245
Cdd:COG2826   279 FPKGTDFSTVTQE--ELDAIADRLNN-RPRKCLGYKTPAEVFAE 319
transpos_IS21 NF033546
IS21 family transposase;
126-245 1.10e-05

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 45.66  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2151987079 126 SKTAEAaLEQALIARFGSLGRVasPFLLRSDN------------GLVFTSRnYTALVKSYGLQQEFITPYTPEQNGMVER 193
Cdd:NF033546  158 SESQED-LLDGHQRAFEFFGGV--PREIVYDNlktavdkrdryeEPRLNPR-FAAFAAHYGFEPRPCRPYRPQEKGKVER 233

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2151987079 194 VIRTLKEQC--AHRQRFETLQHASRVIGDWIQFYNQKRPHQALKmKTPAQAYAE 245
Cdd:NF033546  234 AVGYVRRWFlrLRGRRFESLAELNAALAEWLAELANQRPHGTTG-GSPAERFEE 286
rve_2 pfam13333
Integrase core domain;
197-241 7.53e-05

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 39.55  E-value: 7.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2151987079 197 TLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRphqaLKMKTPAQ 241
Cdd:pfam13333   6 SLKTEMVYGEHFKTLEELELAIFDYIEWYNNKR----LKGLSPVQ 46
transpos_IS630 NF033545
IS630 family transposase;
179-223 5.54e-04

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 40.32  E-value: 5.54e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2151987079 179 FITPYTPEQNgMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQ 223
Cdd:NF033545  254 YLPPYSPWLN-PIERVWAVLKRRLLRNRAFRSVDELREAIDAFLN 297
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
188-242 1.34e-03

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 39.12  E-value: 1.34e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2151987079 188 NGMVERVIRTLKEQCAHRQRFETLQHASRVIGDWIQFYNQKRPHQALKMKTPAQA 242
Cdd:COG3316   163 NNRIERDHRTLKRRERPMRGFKSFRTAQRFLSGFEAYYNFRRPHRSLNGATPARV 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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