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Conserved domains on  [gi|2156569300|ref|WP_230372902|]
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DUF4176 domain-containing protein [Staphylococcus epidermidis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4176 super family cl01867
Domain of unknown function (DUF4176);
5-58 3.50e-14

Domain of unknown function (DUF4176);


The actual alignment was detected with superfamily member COG4495:

Pssm-ID: 470377  Cd Length: 97  Bit Score: 61.13  E-value: 3.50e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 2156569300  5 ACKYPVGVVE-DQIYYFNEENIDNVIFEGYSDQDETRFQELFKDMMGNLYEGIKR 58
Cdd:COG4495   43 GCPYPEGNVGpEKTYLFNHEDIDEVVFEGYEDEEEERFQELLKKALKELEEKKKK 97
 
Name Accession Description Interval E-value
COG4495 COG4495
Uncharacterized conserved protein, DUF4176 domain [Function unknown];
5-58 3.50e-14

Uncharacterized conserved protein, DUF4176 domain [Function unknown];


Pssm-ID: 443583  Cd Length: 97  Bit Score: 61.13  E-value: 3.50e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 2156569300  5 ACKYPVGVVE-DQIYYFNEENIDNVIFEGYSDQDETRFQELFKDMMGNLYEGIKR 58
Cdd:COG4495   43 GCPYPEGNVGpEKTYLFNHEDIDEVVFEGYEDEEEERFQELLKKALKELEEKKKK 97
DUF4176 pfam13780
Domain of unknown function (DUF4176);
5-41 1.73e-09

Domain of unknown function (DUF4176);


Pssm-ID: 433473  Cd Length: 74  Bit Score: 48.32  E-value: 1.73e-09
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 2156569300  5 ACKYPVGVV-EDQIYYFNEENIDNVIFEGYSDQDETRF 41
Cdd:pfam13780 37 GCPYPEGYIdPEKTYLFNHEDIEEVYFEGYQDEEEEAF 74
PRK08645 PRK08645
bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; ...
 12-38 8.24e-03

bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed


Pssm-ID: 236321 [Multi-domain]  Cd Length: 612  Bit Score: 32.51  E-value: 8.24e-03
                          10        20
                  ....*....|....*....|....*..
gi 2156569300  12 VVEDQIYYFNEENIDNVIFEGYSDQDE 38
Cdd:PRK08645  126 EFREQIDALLEEGVDGLLLETFYDLEE 152
 
Name Accession Description Interval E-value
COG4495 COG4495
Uncharacterized conserved protein, DUF4176 domain [Function unknown];
5-58 3.50e-14

Uncharacterized conserved protein, DUF4176 domain [Function unknown];


Pssm-ID: 443583  Cd Length: 97  Bit Score: 61.13  E-value: 3.50e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 2156569300  5 ACKYPVGVVE-DQIYYFNEENIDNVIFEGYSDQDETRFQELFKDMMGNLYEGIKR 58
Cdd:COG4495   43 GCPYPEGNVGpEKTYLFNHEDIDEVVFEGYEDEEEERFQELLKKALKELEEKKKK 97
DUF4176 pfam13780
Domain of unknown function (DUF4176);
5-41 1.73e-09

Domain of unknown function (DUF4176);


Pssm-ID: 433473  Cd Length: 74  Bit Score: 48.32  E-value: 1.73e-09
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 2156569300  5 ACKYPVGVV-EDQIYYFNEENIDNVIFEGYSDQDETRF 41
Cdd:pfam13780 37 GCPYPEGYIdPEKTYLFNHEDIEEVYFEGYQDEEEEAF 74
PRK08645 PRK08645
bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; ...
 12-38 8.24e-03

bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed


Pssm-ID: 236321 [Multi-domain]  Cd Length: 612  Bit Score: 32.51  E-value: 8.24e-03
                          10        20
                  ....*....|....*....|....*..
gi 2156569300  12 VVEDQIYYFNEENIDNVIFEGYSDQDE 38
Cdd:PRK08645  126 EFREQIDALLEEGVDGLLLETFYDLEE 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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