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Conserved domains on  [gi|2161094335|ref|WP_231124713|]
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protein translocase subunit SecF [Piscirickettsia salmonis]

Protein Classification

protein translocase subunit SecF( domain architecture ID 11417410)

protein translocase subunit SecF is part of the Sec protein translocase complex; SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA

Gene Ontology:  GO:0015450|GO:0043952
TCDB:  2.A.6.4

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 2-299 1.52e-129

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 372.08  E-value: 1.52e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   2 EFFKQQTNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTY 81
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  82 GSTRDLQIRFAPQEGQSAGLSETQQGALKAKLkttltlgQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALR 161
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEVEKVRAALKEAF-------GDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 162 FDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDT 241
Cdd:COG0341   154 FEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQT 233

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2161094335 242 LSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGIN 299
Cdd:COG0341   234 LSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 2-299 1.52e-129

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 372.08  E-value: 1.52e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   2 EFFKQQTNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTY 81
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  82 GSTRDLQIRFAPQEGQSAGLSETQQGALKAKLkttltlgQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALR 161
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEVEKVRAALKEAF-------GDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 162 FDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDT 241
Cdd:COG0341   154 FEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQT 233

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2161094335 242 LSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGIN 299
Cdd:COG0341   234 LSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 8-301 2.17e-93

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 294.45  E-value: 2.17e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   8 TNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTYGS-TRD 86
Cdd:PRK13024  447 DRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSdNNQ 526

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  87 LQIRFAPQEGQSaglsETQQGALKAKLKTTLTLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRF 166
Cdd:PRK13024  527 VLVRTYGILSDD----EEADTEIVAKLKNALKNDKGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTF 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 167 AISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTL 246
Cdd:PRK13024  603 SLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTI 682

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2161094335 247 MTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGINRL 301
Cdd:PRK13024  683 NTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEKRRL 737
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 38-289 2.48e-85

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 257.97  E-value: 2.48e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  38 GLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTYGSTRDLQIRFAPQEGQSaglSETQQGALKAKLKTTl 117
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQ---SEELREALEEALKNV- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 118 tlGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISL 197
Cdd:TIGR00966  77 --DPDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 198 AALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIG 277
Cdd:TIGR00966 155 AALLTIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVG 234

                         250
                  ....*....|..
gi 2161094335 278 ILIGTYSSIYIA 289
Cdd:TIGR00966 235 VIVGTYSSIFIA 246
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 109-297 2.20e-64

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 202.45  E-value: 2.20e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 109 LKAKLKTTltlGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLF 188
Cdd:pfam02355   2 VEALLKNV---GPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 189 HIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQ 268
Cdd:pfam02355  79 GIEVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLK 158

                         170       180
                  ....*....|....*....|....*....
gi 2161094335 269 PFALVLIIGILIGTYSSIYIAGALSIKLG 297
Cdd:pfam02355 159 DFSLALLVGVIVGTYSSIFIASPILLDLG 187
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 118-299 5.39e-05

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 45.15  E-value: 5.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  118 TLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYvaLRFDYR-FAISAAVALAHDPLLILGIFSLFHIEFTLIS 196
Cdd:NF037998   422 TSGFTFKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIY--LLFAYRlLGLFAIIIALTSISLTLYSPTWFGLAIGPES 499

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  197 LAALLAVIGFSLNDTVVIYDRIRENFRKmRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLII 276
Cdd:NF037998   500 ITAIFIAIGLVLESCSLLFEAFKKHLYK-NKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLV 578

                          170       180
                   ....*....|....*....|...
gi 2161094335  277 GILIGTYSSIYIAgALSIKLGIN 299
Cdd:NF037998   579 GVIISLVLVIIVA-RLMIWLTIK 600
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 139-221 1.73e-04

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 43.61  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  139 MVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRI 218
Cdd:NF037998   955 QILQIAISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKA 1034


                   ...
gi 2161094335  219 REN 221
Cdd:NF037998  1035 KSL 1037
 
Name Accession Description Interval E-value
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 2-299 1.52e-129

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 372.08  E-value: 1.52e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   2 EFFKQQTNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTY 81
Cdd:COG0341     1 RLFPGNTNIDFMKKRKIWFAISAVLILASIVSLFTRGLNLGIDFTGGTLIEVSFEQPVDLEEVREALEEAGLGDASVQTF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  82 GSTRDLQIRFAPQEGQSAGLSETQQGALKAKLkttltlgQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALR 161
Cdd:COG0341    81 GSDNDVLIRTPPLDGESAEEVEKVRAALKEAF-------GDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 162 FDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDT 241
Cdd:COG0341   154 FEWRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMTLAEIINLSINQT 233

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2161094335 242 LSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGIN 299
Cdd:COG0341   234 LSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 8-301 2.17e-93

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 294.45  E-value: 2.17e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   8 TNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTYGS-TRD 86
Cdd:PRK13024  447 DRIDFVKKRKWFLIFSIVLVIAGIIIFFIFGLNLGIDFTGGTRYEIRTDQPVDLEQVRADLKELGLGEVNIVTFGSdNNQ 526

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  87 LQIRFAPQEGQSaglsETQQGALKAKLKTTLTLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRF 166
Cdd:PRK13024  527 VLVRTYGILSDD----EEADTEIVAKLKNALKNDKGGTIPSSETVGPTVGKELARNAIIAVLIALIGILLYILIRFEWTF 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 167 AISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTL 246
Cdd:PRK13024  603 SLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLYKKKDLREIVNKSINQTLSRTI 682

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2161094335 247 MTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGINRL 301
Cdd:PRK13024  683 NTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSSIFIAAPLWLDLEKRRL 737
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 38-289 2.48e-85

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 257.97  E-value: 2.48e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  38 GLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTYGSTRDLQIRFAPQEGQSaglSETQQGALKAKLKTTl 117
Cdd:TIGR00966   1 GFNFGIDFTGGTVIETRLEQAADVAEVRDVLEKAGIEGVVIQEFGSSHTIMIRIPTLDTEQ---SEELREALEEALKNV- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 118 tlGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISL 197
Cdd:TIGR00966  77 --DPDAEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFEWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 198 AALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIG 277
Cdd:TIGR00966 155 AALLTIIGYSINDTVVVFDRIRENLRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVG 234

                         250
                  ....*....|..
gi 2161094335 278 ILIGTYSSIYIA 289
Cdd:TIGR00966 235 VIVGTYSSIFIA 246
PRK14726 PRK14726
protein translocase subunit SecDF;
3-294 1.44e-71

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 238.47  E-value: 1.44e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   3 FFKQQTNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQV-SYVKAPDLTKVRNALDAANFREARVTTY 81
Cdd:PRK14726  540 GLFEGANIRFMGIRRYVFTLSAALSLASLVLFATVGLNLGIDFTGGSLIEVrAKQGNADIADIRARLNELNLGEVQVERF 619

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  82 GSTRDLQIRFAPQEGqsaGLSETQQGALKAKLKttltLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALR 161
Cdd:PRK14726  620 GSPRDALIRIASQDG---GENAEQSAVTLVRGE----LEDDYDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIWIR 692

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 162 FDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDT 241
Cdd:PRK14726  693 FEWQFAVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKMPLPILIDASINQT 772

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2161094335 242 LSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSI 294
Cdd:PRK14726  773 LSRTVLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPVLI 825
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 9-299 6.95e-66

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 210.10  E-value: 6.95e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   9 NIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKAPDLTKVRNALDAANFREARVTTYGSTRDLQ 88
Cdd:PRK13021    3 NINLTKWRYISSAISIVLMLLSLTIIGVKGFNWGLDFTGGVVTEVQLDRKITSSELQPLLNAAYQQEVSVISASEPGRWV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  89 IRFA--PQEGQSAGLSETqqgalkaklktTLTLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRF 166
Cdd:PRK13021   83 LRYApaDTAQSNVDIQQA-----------LAPLGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWRL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 167 AISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTL 246
Cdd:PRK13021  152 ASGALFALVHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIVATFSRTM 231

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2161094335 247 MTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGIN 299
Cdd:PRK13021  232 VTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELLGLS 284
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 109-297 2.20e-64

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 202.45  E-value: 2.20e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 109 LKAKLKTTltlGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLF 188
Cdd:pfam02355   2 VEALLKNV---GPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEWRFALGAIIALAHDVIITVGVFSLF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 189 HIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQ 268
Cdd:pfam02355  79 GIEVDLATVAALLTIIGYSVNDTVVVFDRVRENLRKKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLK 158

                         170       180
                  ....*....|....*....|....*....
gi 2161094335 269 PFALVLIIGILIGTYSSIYIAGALSIKLG 297
Cdd:pfam02355 159 DFSLALLVGVIVGTYSSIFIASPILLDLG 187
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 123-286 6.31e-51

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 168.20  E-value: 6.31e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 123 VEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLA 202
Cdd:TIGR00916  29 ISAPVVGTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLT 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 203 VIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGT 282
Cdd:TIGR00916 109 IIGYSVDDTVVIFDRIREELRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGT 188


                  ....
gi 2161094335 283 YSSI 286
Cdd:TIGR00916 189 YSSI 192
PRK13023 PRK13023
protein translocase subunit SecDF;
8-298 3.40e-45

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 164.79  E-value: 3.40e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   8 TNIDFLGLRRWAGIFSVVICLGSIAIMAIKGLNWGLDFTGGYSVQVSYVKA-PDLTKVRNALDAANFREARVTTYGSTRD 86
Cdd:PRK13023  451 THIPFMRLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVELQARNGdANLEDINERLAELNIDSARVLPAKSPRS 530

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  87 LQIRFAPQEgqsagLSETQQGALKAKLKTTLTlgQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYRF 166
Cdd:PRK13023  531 ALVIIGSQE-----VGDDAEQTVAVKLRGEFE--QDYSFQRVDVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQL 603

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 167 AISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKATPVEVVNRSINDTLSRTL 246
Cdd:PRK13023  604 ALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTL 683

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2161094335 247 MTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGALSIKLGI 298
Cdd:PRK13023  684 LTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLVQFGL 735
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 11-292 1.24e-41

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 155.40  E-value: 1.24e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   11 DFL-GLRRWAGIFSVVICLGSIAImaikGLN-W----GLDFTGGY--SVQVSYVKAPDLTKVRNALdAANFREA------ 76
Cdd:PRK12911  1082 DFLkECKRLWVVSGSVLVLGCVAL----GFGaWnsvlGMDFKGGYalTLDPSDVCEYDVEQMRSKL-RKKFQQIglssrd 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   77 -RVTTYGSTRDLQIRFApqegQSAgLSETQQGALKAKLKTTLTLGQPVEI-----------------NSLNYIGSEVGSE 138
Cdd:PRK12911  1157 fRIRTFDSSEKIKIYFS----QNA-LDRVEAIEGAGSEQSDHHLALVLGVlsdtgsdtssevfdatqNFWFKVSGQLSNK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  139 MVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPL-----LILGIFSLFHIEFTLISLAALLAVIGFSLNDTVV 213
Cdd:PRK12911  1232 MRTQAVIALFGALGIILLYVSLRFEWRYAFSAICALIHDLLatcavLVALHFFLQKIQIDLQAIGALMTVLGYSLNNTLI 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  214 IYDRIRENfRKMRKATPVEV-VNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGAL 292
Cdd:PRK12911  1312 IFDRIRED-RQEKLFTPMPIlINDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAFIMTIGILLGTLSSLYIAPPL 1390
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 122-292 1.03e-21

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 95.57  E-value: 1.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 122 PVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRfdYR-FAISAAVALAHDPLLILGIFSLFHIEFTLISLAAL 200
Cdd:COG0342   252 PLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLY--YRlPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGI 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 201 LAVIGFSLNDTVVIYDRIRENFRKMRkaTPVEVVNRSINDTLSrTLMTSGLT-LLVVIILYVFGGPALQPFALVLIIGIL 279
Cdd:COG0342   330 ILTIGMAVDANVLIFERIREELRAGR--SLRAAIEAGFKRAFS-TILDANVTtLIAAVVLFVLGTGPVKGFAVTLILGIL 406

                         170
                  ....*....|...
gi 2161094335 280 IGTYSSIYIAGAL 292
Cdd:COG0342   407 ISMFTAVPVTRPL 419
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 86-292 2.96e-21

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 93.89  E-value: 2.96e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  86 DLQIRFAPQEGQSAGLSETQ-QGALKAK----LKTTL---TLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVY 157
Cdd:TIGR01129 185 DNKVVSAPTIQEAITGGSGQiTGNFTAEeandLALVLrsgALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVF 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 158 VALRfdYR-FAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRkaTPVEVVNR 236
Cdd:TIGR01129 265 MILY--YRlFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGK--SVRQAIEA 340

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2161094335 237 SINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGTYSSIYIAGAL 292
Cdd:TIGR01129 341 GFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLL 396
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 122-289 1.57e-17

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 83.74  E-value: 1.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 122 PVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVAlrFDYRFA-ISAAVALAHDPLLILGIFSLFHIEFTLISLAAL 200
Cdd:PRK13024  247 PLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFML--VYYGLPgLIANIALLLYIFLTLGALSSLGAVLTLPGIAGL 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 201 LAVIGFSLNDTVVIYDRIRENFRKMRKatpvevVNRSINDTLSRTLMT---SGLT-LLVVIILYVFGGPALQPFALVLII 276
Cdd:PRK13024  325 VLGIGMAVDANVLIFERIKEELRKGKS------LKKAFKKGFKNAFSTildSNITtLIAAAILFFFGTGPVKGFATTLII 398

                         170
                  ....*....|...
gi 2161094335 277 GILIGTYSSIYIA 289
Cdd:PRK13024  399 GILASLFTAVFLT 411
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 122-288 6.70e-17

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 81.42  E-value: 6.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 122 PVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRfdYR-FAISAAVALAHDPLLILGIFSLFHIEFTLISLAAL 200
Cdd:PRK05812  278 PLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILY--YRlFGLIANIALVANLVLILAVLSLLGATLTLPGIAGI 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 201 LAVIGFSLNDTVVIYDRIRENFRKMRKatpvevVNRSINDTLSR---TLMTSGLT-LLVVIILYVFGGPALQPFALVLII 276
Cdd:PRK05812  356 VLTIGMAVDANVLIFERIREELREGRS------LRSAIEAGFKRafsTILDSNITtLIAAIILYALGTGPVKGFAVTLGI 429

                         170
                  ....*....|..
gi 2161094335 277 GILIGTYSSIYI 288
Cdd:PRK05812  430 GILTSMFTAITV 441
PRK14726 PRK14726
protein translocase subunit SecDF;
95-279 3.78e-13

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 70.52  E-value: 3.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  95 EGQSAGlSETQQGA------LKA-KLKTTLTLgqpVEINSlnyIGSEVGSEMVQQGVLAIIVSVLAIMV--YVALRFdyr 165
Cdd:PRK14726  326 EGRISG-NFSEQGAndlavlLRAgALPATLTV---VEERT---VGPGLGADSIAAGLVAGLIAAILVAAlmIGFYGF--- 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 166 FAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRKatpvevVNRSINDTLSRT 245
Cdd:PRK14726  396 LGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHS------LIQALDRGFSRA 469

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2161094335 246 LMT---SGLTLLVV-IILYVFGGPALQPFALVLIIGIL 279
Cdd:PRK14726  470 LATivdANVTILIAaVILFFLGSGAVRGFAVTLAVGIL 507
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 21-279 5.52e-12

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 65.34  E-value: 5.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  21 IFSVVIcLGSIAIMAIKGLNWGLDFTGGYSVQVsYVKAPDLTKVRNALDAANFREARVTTYGSTRdlqIRFAPQEgqsag 100
Cdd:PRK08578   25 LLSLLL-LGGTFATTGSPVKLGIDFTGGTEITI-QTNDASPDELESALSGEPGVDVRKGSGNGYI---ITFGSGD----- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 101 lsETQQGALKAKLKTTLTLGQ-PVEINSLNYIGSEVGSEMVQQGVLAIIVSVL--AIMVYVALRfdyRFAISAAV--ALA 175
Cdd:PRK08578   95 --DTDVDKLADAVKEFFNVDSiSELNYSEKQIGPTFGSQFQEQALKAVGFAFIgmAVVVFLIFR---TPVPSLAVilSAF 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 176 HDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIREnfrkmRKATPVEVVNRSINDTLSRTLMTSGLTLLV 255
Cdd:PRK08578  170 SDIIIALALMNLFGIELSLATVAALLMLIGYSVDSDILLTTRVLK-----RRGTFDESIKRAMRTGITMTLTTIAAMAVL 244

                         250       260
                  ....*....|....*....|....
gi 2161094335 256 VIILYVFGGPALQPFALVLIIGIL 279
Cdd:PRK08578  245 YIVSTIPQAEVLANIAAVLIFGLL 268
secD PRK08343
preprotein translocase subunit SecD; Reviewed
 122-281 1.46e-09

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 236245 [Multi-domain]  Cd Length: 417  Bit Score: 59.12  E-value: 1.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 122 PVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRF-DYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAAL 200
Cdd:PRK08343  242 KLDIEGSGSVSPSLGEQFKKGSLIAGLLALLAVALVVFLRYrEPRIALPMVITSLSEVIIILGFAALIGWQLDLASIAGI 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 201 LAVIGFSLNDTVVIYDRIrenfRKMRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILI 280
Cdd:PRK08343  322 IAVIGTGVDDLIIITDEV----LHEGKVPSRKVFLSRIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVLI 397


                  .
gi 2161094335 281 G 281
Cdd:PRK08343  398 G 398
PRK13023 PRK13023
protein translocase subunit SecDF;
95-278 1.68e-09

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 59.25  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  95 EGQSAGLSETQQGALKAKLKTTLTLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDYrFAISAAVAL 174
Cdd:PRK13023  232 ELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGI-LGVIALVAL 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 175 AHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKmrKATPVEVVNRSINDTLSRTLMTSGLTLL 254
Cdd:PRK13023  311 VVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRK--GYSVVQAMESGFYRALSTIVDANLTTLI 388

                         170       180
                  ....*....|....*....|....
gi 2161094335 255 VVIILYVFGGPALQPFALVLIIGI 278
Cdd:PRK13023  389 AALVLFLLGSGTVHGFALTVAIGI 412
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 124-289 1.22e-08

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 56.79  E-value: 1.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  124 EINSLNYIGSEVGSEMVQQGVLAII--VSVLAIMVYVALRFDyrfAISAAVALAHDPLLILGIFSLFHIEFTLISLAALL 201
Cdd:PRK12911   892 EVLSEEVISPELGKSQRTQGIISVClgLAVLIVLMSVYYRFG---GVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIV 968

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  202 AVIGFSLNDTVVIYDRIRENFRKMRKATpvEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGIlig 281
Cdd:PRK12911   969 LAMGMAVDANVLVFERIREEYLLSRSLS--ESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGI--- 1043


                   ....*...
gi 2161094335  282 tYSSIYIA 289
Cdd:PRK12911  1044 -FSSMFTA 1050
secD PRK12933
protein translocase subunit SecD;
101-292 1.29e-08

protein translocase subunit SecD;


Pssm-ID: 183831 [Multi-domain]  Cd Length: 604  Bit Score: 56.23  E-value: 1.29e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 101 LSETQQGALkakLKTTLTLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYVALRFDyRFAISAAVALAHDPLL 180
Cdd:PRK12933  403 YQEAQQLAL---LLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGITLLFMALWYR-RLGWVANVALIANMVC 478

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 181 ILGIFSLF-HIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKMRkaTPVEVVNRSINDTLSRTLMTSGLTLLVVIIL 259
Cdd:PRK12933  479 LFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGR--SFAQAIDTGFDSAFSTIFDANFTTMITAVVL 556

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2161094335 260 YVFGGPALQPFALVLIIGILIGTYSSIYIAGAL 292
Cdd:PRK12933  557 YSIGNGPIQGFALTLGLGLLTSMFTGIFASRAL 589
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 118-299 5.39e-05

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 45.15  E-value: 5.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  118 TLGQPVEINSLNYIGSEVGSEMVQQGVLAIIVSVLAIMVYvaLRFDYR-FAISAAVALAHDPLLILGIFSLFHIEFTLIS 196
Cdd:NF037998   422 TSGFTFKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIY--LLFAYRlLGLFAIIIALTSISLTLYSPTWFGLAIGPES 499

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  197 LAALLAVIGFSLNDTVVIYDRIRENFRKmRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLII 276
Cdd:NF037998   500 ITAIFIAIGLVLESCSLLFEAFKKHLYK-NKRSIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLV 578

                          170       180
                   ....*....|....*....|...
gi 2161094335  277 GILIGTYSSIYIAgALSIKLGIN 299
Cdd:NF037998   579 GVIISLVLVIIVA-RLMIWLTIK 600
Sec_GG pfam07549
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ...
 33-58 1.26e-04

SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.


Pssm-ID: 462205 [Multi-domain]  Cd Length: 27  Bit Score: 38.42  E-value: 1.26e-04
                          10        20
                  ....*....|....*....|....*.
gi 2161094335  33 IMAIKGLNWGLDFTGGYSVQVSYVKA 58
Cdd:pfam07549   1 SLFTRGLNLGLDFTGGTVIELQFDQP 26
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
129-280 1.32e-04

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 43.70  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 129 NYIGSEVGSEMVQQGVLAIIVsvLAIMVYVALRfDYR----FAISAAVALahdpLLILGIFSLFHIEFTLIS--LAALLA 202
Cdd:COG1033   210 GDIAEAIQSDLAIFFPLALLL--ILLLLFLFFR-SLRgvllPLLVVLLAV----IWTLGLMGLLGIPLSPLTilVPPLLL 282

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2161094335 203 VIGFSlnDTVVIYDRIRENFRkmRKATPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILI 280
Cdd:COG1033   283 AIGID--YGIHLLNRYREERR--KGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLL 356
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 139-221 1.73e-04

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 43.61  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  139 MVQQGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLAALLAVIGFSLNDTVVIYDRI 218
Cdd:NF037998   955 QILQIAISFAIILLALIVYILIRFKWTYYVALALAIVFAPAITVSIVIIFRVPITFEILIAFVSIIGFAIASAIIILGKA 1034


                   ...
gi 2161094335  219 REN 221
Cdd:NF037998  1035 KSL 1037
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 77-288 2.20e-04

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 43.05  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335   77 RVTTYGSTRDLQIRFAPQEGQSAGLSETQQGALKAKLKttLTLGQPVEINSLNYigsevgSEMVQQGVLAIIVSVLAIMV 156
Cdd:pfam00873  804 SINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVK--LPPGYGYTWTGQFE------QEQLAGNSLPILIALALLVV 875

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  157 YVALRFDYRFAISAAVALAHDPLLILGIF---SLFHIEFTLISLAALLAVIGFSLNDTVVIYDRIRENFRKmRKATPVEV 233
Cdd:pfam00873  876 FLVLAALYESWSDPLSIMLTVPLALVGALlalWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQ-EGKSLEEA 954

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2161094335  234 VNRSINDTLSRTLMTSGLTLLVVIILYVFGGP---ALQPFALVLIIGILIGTYSSIYI 288
Cdd:pfam00873  955 ILEACRLRLRPILMTALAAILGVLPLALSTGAgseLQQPLGIVVFGGLVTSTVLTLLV 1012
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 137-293 2.32e-04

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 43.05  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  137 SEMVQQGVLAIIVSVLAimVYVALRfDYRFAISAAVALahdPLLILGIFSL---FHIEFTLISLAALLAVIGFSLNDTVV 213
Cdd:pfam00873  331 EEVVKTLLEAIVLVILV--MFLFLQ-NWRATLIPAIAI---PLSLLGTFAVmkaFGFSINTLTLGGLVLAIGLVVDDAIV 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  214 IYDRIRENFRkMRKATPVEVVNRSINdTLSRTLMTSGLTLLVVII-LYVFGGPA---LQPFALVLIIGILIGTYSSIYIA 289
Cdd:pfam00873  405 VVENIERVLE-ENGLKPLEAAYKSMG-EIGGALVAIALVLSAVFLpILFLGGLTgriFRQFAITIVLAILLSVLVALTLT 482


                   ....
gi 2161094335  290 GALS 293
Cdd:pfam00873  483 PALC 486
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 127-294 6.97e-04

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 41.36  E-value: 6.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 127 SLNY-IGSEVGSEMVqqgvlaIIVSVLAIMVYVALRFDYRFAISAAVALA---HDPLLILGIFSLFHIEFTLISLAALLA 202
Cdd:TIGR00921 182 AINYdIEREFGKDMG------TTMAISGILVVLVLLLDFKRWWRPLLPLViilFGVAWVLGIMGWLGIPLYATTLLAVPM 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 203 VIGFSLNDTVVIYDRIRENFRKMRkaTPVEVVNRSINDTLSRTLMTSGLTLLVVIILYVFGGPALQPFALVLIIGILIGT 282
Cdd:TIGR00921 256 LIGVGIDYGIQTLNRYEEERDIGR--AKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAY 333

                         170
                  ....*....|..
gi 2161094335 283 YSSIYIAGALSI 294
Cdd:TIGR00921 334 LLTLLVLPALLQ 345
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
137-280 2.55e-03

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 39.70  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335  137 SEMVQQGVLAIIVSVLaiMVYVALRfDYRFAISAAVALahdPLLILG---IFSLFHIEFTLISLAALLAVIGFSLND-TV 212
Cdd:COG0841    331 EEVVKTLLEAILLVVL--VVFLFLR-SWRATLIPAVAI---PVSLIGtfaVMYLLGFSLNILTLFALVLAIGIVVDDaIV 404

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2161094335  213 VIydrirEN-FRKMRK-ATPVEVVNRSINDtLSRTLMTSGLTLLVVII-LYVFGGPA---LQPFALVLIIGILI 280
Cdd:COG0841    405 VV-----ENiERHMEEgLSPLEAAIKGARE-VAGAVIASTLTLVAVFLpLAFMGGITgqlFRQFALTVAIALLI 472
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 120-279 5.96e-03

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 38.66  E-value: 5.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 120 GQPVEINSLNYIGSEVGSEMVQ-QGVLAIIVSVLAIMVYVALRFDYRFAISAAVALAHDPLLILGIFSLFHIEFTLISLA 198
Cdd:TIGR00921 546 GVKVGVTGLPVAFAEMHELVNEgMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMAT 625

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 199 ALLAVIGFSLNDTVVIYDRIRENfrkmRKA-TPVEVVNRSInDTLSRTLMTSGLTLLVVIILYVFGG-PALQPFALVLII 276
Cdd:TIGR00921 626 TISIILGLGMDYSIHLAERYFEE----RKEhGPKEAITHTM-ERTGPGILFSGLTTAGGFLSLLLSHfPIMRNFGLVQGI 700


                  ...
gi 2161094335 277 GIL 279
Cdd:TIGR00921 701 GVL 703
COG4258 COG4258
Predicted exporter [General function prediction only];
147-279 8.11e-03

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 38.30  E-value: 8.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2161094335 147 IIVSVLAIMVYVALRFdYRFAISAAVALahdPLLI-----LGIFSLFHIEFTLISLAALLAVIGFSLNDTVviydriren 221
Cdd:COG4258   645 LLLALLLILLLLLLRL-RSLRRALRVLL---PPLLavlltLAILGLLGIPLNLFHLIALLLVLGIGIDYAL--------- 711

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2161094335 222 FrkMRKATPVEvvnrsinDTLSRTLMT---SGLTLLVVIILYVFGG-PALQPFALVLIIGIL 279
Cdd:COG4258   712 F--FTEGLLDK-------GELARTLLSillAALTTLLGFGLLAFSStPALRSFGLTVLLGIL 764
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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