NCBI Conserved Domain Search

Conserved domains on [gi|2181075557|ref|WP_235120559|]

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oligopeptide ABC transporter ATP-binding protein AppF [Bacillus subtilis]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11468491)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including dipeptides and oligopeptides

CATH: 3.40.50.300

Gene Ontology: GO:0005524|GO:0016887|GO:0140359|GO:0042626

PubMed: 25750732|24638992

SCOP: 4003976

TCDB: 3.A.1

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

3-328

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 637.16 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ 82
Cdd:COG4608     1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFS 162
Cdd:COG4608    81 DITGLSGRELRP-LRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMEL 242
Cdd:COG4608   160 GGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 243 TGKFELYDNPLHPYTQALLSSVPVTRKRGsvKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAAPSHF 322
Cdd:COG4608   240 APRDELYARPLHPYTQALLSAVPVPDPER--RRERIVLEGDVPSPLNPPSGCRFHTRCPYAQDRCATEEPPLREVGPGHQ 317


                  ....*.
gi 2181075557 323 VACHLY 328
Cdd:COG4608   318 VACHLA 323

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

3-328

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 637.16 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ 82
Cdd:COG4608     1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFS 162
Cdd:COG4608    81 DITGLSGRELRP-LRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMEL 242
Cdd:COG4608   160 GGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 243 TGKFELYDNPLHPYTQALLSSVPVTRKRGsvKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAAPSHF 322
Cdd:COG4608   240 APRDELYARPLHPYTQALLSAVPVPDPER--RRERIVLEGDVPSPLNPPSGCRFHTRCPYAQDRCATEEPPLREVGPGHQ 317


                  ....*.
gi 2181075557 323 VACHLY 328
Cdd:COG4608   318 VACHLA 323

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

6-326

1.53e-166

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 466.36 E-value: 1.53e-166

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFPIRSGLFqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGR--TMIRlyKPTEGQILFKGQD 83
Cdd:PRK11308    2 QQPLLQAIDLKKHYPVKRGLF-KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARllTMIE--TPTGGELYYQGQD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSEEKlRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSG 163
Cdd:PRK11308   79 LLKADPEA-QKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:PRK11308  158 GQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 244 GKFELYDNPLHPYTQALLSSVPvtRKRGSVKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAApSHFV 323
Cdd:PRK11308  238 TKEQIFNNPRHPYTQALLSATP--RLNPDDRRERIKLTGELPSPLNPPPGCAFNARCPRAFGRCRQEQPQLRDYD-GRLV 314


                  ...
gi 2181075557 324 ACH 326
Cdd:PRK11308  315 ACF 317

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

9-241

8.16e-127

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 361.82 E-value: 8.16e-127

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:cd03257     1 LLEVKNLSVSFP-------TGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EeKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYT-MRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQ 167
Cdd:cd03257    74 R-RLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSkKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQ 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:cd03257   153 RVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVE 226

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

8-268

2.92e-81

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 247.41 E-value: 2.92e-81

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpiRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNL 87
Cdd:TIGR02769   1 SLLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 SEEKlRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQ 167
Cdd:TIGR02769  79 DRKQ-RRAFRRDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFE 247
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQ 237

                         250       260
                  ....*....|....*....|....*
gi 2181075557 248 LyDNPLHPYTQALLSSV----PVTR 268
Cdd:TIGR02769 238 L-LSFKHPAGRNLQSAVlpehPVRR 261

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

36-187

1.71e-47

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 157.04 E-value: 1.71e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFasLNPRK 115
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE----RKSLRKEIGYVFQDPQ--LFPRL 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 116 TLRSIIKEPFNTHNMYTmRERNEKVEELLARVGL---HPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:pfam00005  75 TVRENLRLGLLLKGLSK-REKDARAEEALEKLGLgdlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148

GguA

NF040905

sugar ABC transporter ATP-binding protein;

9-241

5.99e-23

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 99.09 E-value: 5.99e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrtmirLYK------PT---EGQILF 79
Cdd:NF040905    1 ILEMRGITKTFP-----------GVKALDDVNLSVREGEIHALCGENGAGKST-------LMKvlsgvyPHgsyEGEILF 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQ-----DIsnlseeklRKSVRKNIQMVFQD----PFASL-------NPRKTlRSIIKepfnthnmytMRERNEKVEEL 143
Cdd:NF040905   63 DGEvcrfkDI--------RDSEALGIVIIHQElaliPYLSIaeniflgNERAK-RGVID----------WNETNRRAREL 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 144 LARVGLHPSfagryPHEFSG----GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISH 219
Cdd:NF040905  124 LAKVGLDES-----PDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISH 197

                         250       260
                  ....*....|....*....|..
gi 2181075557 220 DLSVVRHISDRVGVMYLGKMME 241
Cdd:NF040905  198 KLNEIRRVADSITVLRDGRTIE 219

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

31-231

8.54e-19

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 82.67 E-value: 8.54e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQD----ISNLSE--EKLRKSVRKN 99
Cdd:NF040873    3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTllkvlAG-----VLRPTSGTVRRAGGArvayVPQRSEvpDSLPLTVRDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 100 IQMVFqdpFASLNPRKTLRsiikepfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:NF040873   78 VAMGR---WARRGLWRRLT---------------RDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEA 138

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:NF040873  139 DLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

28-192

1.86e-14

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 74.01 E-value: 1.86e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrTM---IRLYKPTEGQILFKGQ--DISNLSeekLRK-------- 94
Cdd:NF033858  274 MRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKST---TMkmlTGLLPASEGEAWLFGQpvDAGDIA---TRRrvgymsqa 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  95 -------SVRKNIQM---VFQDPFASLNPRktlrsiikepfnthnmytmrernekVEELLARVGLHPsFAGRYPHEFSGG 164
Cdd:NF033858  348 fslygelTVRQNLELharLFHLPAAEIAAR-------------------------VAEMLERFDLAD-VADALPDSLPLG 401

                         170       180
                  ....*....|....*....|....*...
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:NF033858  402 IRQRLSLAVAVIHKPELLILDEPTSGVD 429

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

31-187

2.64e-10

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 61.29 E-value: 2.64e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMIRlykptEGQILFKGQDISNLSEEK------------LR 93
Cdd:NF033858   12 GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSllsliAGARKIQ-----QGRVEVLGGDMADARHRRavcpriaympqgLG 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  94 K------SVRKNIQmvFqdpFASLnprktlrsiikepFNtHNMytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQ 167
Cdd:NF033858   87 KnlyptlSVFENLD--F---FGRL-------------FG-QDA---AERRRRIDELLRATGLAP-FADRPAGKLSGGMKQ 143

                         170       180
                  ....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEP 187
Cdd:NF033858  144 KLGLCCALIHDPDLLILDEP 163

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

10-245

5.32e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 59.75 E-value: 5.32e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTaGRTMIRLYKPTEGQILFKGQD-ISNls 88
Cdd:NF000106   14 VEVRGLVKHF-----------GEVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRRPWRF*TwCAN-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 eeklRKSVRKNIqmvfqdpfaslNPRKTLRSIIKEPFN-THNMYTM--------RERNEKVEELLARVGLHPSfAGRYPH 159
Cdd:NF000106   80 ----RRALRRTI-----------G*HRPVR*GRRESFSgRENLYMIgr*ldlsrKDARARADELLERFSLTEA-AGRAAA 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLF---------ISHDLSVVrhisDR 230
Cdd:NF000106  144 KYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTtqymeeaeqLAHELTVI----DR 219

                         250
                  ....*....|....*
gi 2181075557 231 VGVMYLGKMMELTGK 245
Cdd:NF000106  220 GRVIADGKVDELKTK 234

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

45-231

6.94e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.92 E-value: 6.94e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   45 KGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFkgqdisnlseeklrksvrkniqmvfqdpfasLNPRKTLRSiikep 124
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-------------------------------IDGEDILEE----- 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  125 fnthnmytmrernekveellARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVI---- 200
Cdd:smart00382  45 --------------------VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLllee 104

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2181075557  201 -NLMEELQEEFNLTYLFISHDLSV-----VRHISDRV 231
Cdd:smart00382 105 lRLLLLLKSEKNLTVILTTNDEKDlgpalLRRRFDRR 141

GguA

NF040905

sugar ABC transporter ATP-binding protein;

7-246

6.48e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 6.48e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSglfQRKVgdvkaVDGVSFSLKKGETLGIVGESGcgkstAGRTMI------RLY-KPTEGQILF 79
Cdd:NF040905  255 EVVFEVKNWTVYHPLHP---ERKV-----VDDVSLNVRRGEIVGIAGLMG-----AGRTELamsvfgRSYgRNISGTVFK 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQ--DISNLSE----------EKlRK--------SVRKNIQMvfqdpfASLnPRKTLRSIIkepfNTHNMYTMRER--- 136
Cdd:NF040905  322 DGKevDVSTVSDaidaglayvtED-RKgyglnlidDIKRNITL------ANL-GKVSRRGVI----DENEEIKVAEEyrk 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 137 --NEKVEELLARVGlhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTY 214
Cdd:NF040905  390 kmNIKTPSVFQKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGV 457

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2181075557 215 LFISHDLSVVRHISDRVGVMYLGKmmeLTGKF 246
Cdd:NF040905  458 IVISSELPELLGMCDRIYVMNEGR---ITGEL 486

Name

Accession

Description

Interval

E-value

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

3-328

0e+00

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 637.16 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ 82
Cdd:COG4608     1 AAMAEPLLEVRDLKKHFPVRGGLFGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFS 162
Cdd:COG4608    81 DITGLSGRELRP-LRRRMQMVFQDPYASLNPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYPHEFS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMEL 242
Cdd:COG4608   160 GGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 243 TGKFELYDNPLHPYTQALLSSVPVTRKRGsvKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAAPSHF 322
Cdd:COG4608   240 APRDELYARPLHPYTQALLSAVPVPDPER--RRERIVLEGDVPSPLNPPSGCRFHTRCPYAQDRCATEEPPLREVGPGHQ 317


                  ....*.
gi 2181075557 323 VACHLY 328
Cdd:COG4608   318 VACHLA 323

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

9-328

0e+00

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 530.40 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP---TEGQILFKGQDIS 85
Cdd:COG0444     1 LLEVRNLKVYFPTRRG-------VVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  86 NLSEEKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHP--SFAGRYPHEFSG 163
Cdd:COG0444    74 KLSEKELRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDpeRRLDRYPHELSG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:COG0444   154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 244 GKFELYDNPLHPYTQALLSSVPVTRKRGsvkRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAAPSHFV 323
Cdd:COG0444   234 PVEELFENPRHPYTRALLSSIPRLDPDG---RRLIPIPGEPPSLLNPPSGCRFHPRCPYAMDRCREEEPPLREVGPGHRV 310


                  ....*
gi 2181075557 324 ACHLY 328
Cdd:COG0444   311 ACHLY 315

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

6-326

1.53e-166

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 466.36 E-value: 1.53e-166

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFPIRSGLFqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGR--TMIRlyKPTEGQILFKGQD 83
Cdd:PRK11308    2 QQPLLQAIDLKKHYPVKRGLF-KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARllTMIE--TPTGGELYYQGQD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSEEKlRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSG 163
Cdd:PRK11308   79 LLKADPEA-QKLLRQKIQIVFQNPYGSLNPRKKVGQILEEPLLINTSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:PRK11308  158 GQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 244 GKFELYDNPLHPYTQALLSSVPvtRKRGSVKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEAApSHFV 323
Cdd:PRK11308  238 TKEQIFNNPRHPYTQALLSATP--RLNPDDRRERIKLTGELPSPLNPPPGCAFNARCPRAFGRCRQEQPQLRDYD-GRLV 314


                  ...
gi 2181075557 324 ACH 326
Cdd:PRK11308  315 ACF 317

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

2-325

2.97e-157

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 442.99 E-value: 2.97e-157

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   2 TAANQETILELRDVKKYFPIRSG--LFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILF 79
Cdd:PRK15079    1 VTEGKKVLLEVADLKVHFDIKDGkqWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQDISNLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNT-HNMYTMRERNEKVEELLARVGLHPSFAGRYP 158
Cdd:PRK15079   81 LGKDLLGMKDDEWRA-VRSDIQMIFQDPLASLNPRMTIGEIIAEPLRTyHPKLSRQEVKDRVKAMMLKVGLLPNLINRYP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 159 HEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:PRK15079  160 HEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGH 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 239 MMELTGKFELYDNPLHPYTQALLSSVPVTrkrgSVKRERI----VLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEF 314
Cdd:PRK15079  240 AVELGTYDEVYHNPLHPYTKALMSAVPIP----DPDLERNktiqLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVL 315

                         330
                  ....*....|.
gi 2181075557 315 kEAAPSHFVAC 325
Cdd:PRK15079  316 -EGSFRHAVSC 325

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

2-266

7.64e-152

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 436.26 E-value: 7.64e-152

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   2 TAANQETILELRDVKKYFPIRSGlfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKG 81
Cdd:COG1123   253 AAAAAEPLLEVRNLSKRYPVRGK------GGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDG 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEF 161
Cdd:COG1123   327 KDLTKLSRRSLRE-LRRRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYPHEL 405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:COG1123   406 SGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVE 485

                         250       260
                  ....*....|....*....|....*
gi 2181075557 242 LTGKFELYDNPLHPYTQALLSSVPV 266
Cdd:COG1123   486 DGPTEEVFANPQHPYTRALLAAVPS 510

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

3-265

9.04e-145

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 418.70 E-value: 9.04e-145

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYkPTEGQILFKGQ 82
Cdd:COG4172   269 PPDAPPLLEARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQ 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRkSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNM-YTMRERNEKVEELLARVGLHPSFAGRYPHEF 161
Cdd:COG4172   348 DLDGLSRRALR-PLRRRMQVVFQDPFGSLSPRMTVGQIIAEGLRVHGPgLSAAERRARVAEALEEVGLDPAARHRYPHEF 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:COG4172   427 SGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVE 506

                         250       260
                  ....*....|....*....|....
gi 2181075557 242 LTGKFELYDNPLHPYTQALLSSVP 265
Cdd:COG4172   507 QGPTEQVFDAPQHPYTRALLAAAP 530

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

9-241

8.16e-127

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 361.82 E-value: 8.16e-127

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:cd03257     1 LLEVKNLSVSFP-------TGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EeKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYT-MRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQ 167
Cdd:cd03257    74 R-RLRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSkKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQ 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:cd03257   153 RVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVE 226

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

10-265

4.87e-117

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 337.93 E-value: 4.87e-117

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNlse 89
Cdd:COG1124     2 LEVRNLSVSYGQGGR-------RVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTR--- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMytmRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRI 169
Cdd:COG1124    72 -RRRKAFRRRVQMVFQDPYASLHPRHTVDRILAEPLRIHGL---PDREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRV 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELY 249
Cdd:COG1124   148 AIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227

                         250
                  ....*....|....*.
gi 2181075557 250 DNPLHPYTQALLSSVP 265
Cdd:COG1124   228 AGPKHPYTRELLAASL 243

PRK10261

glutathione transporter ATP-binding protein; Provisional

2-324

1.66e-108

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 329.12 E-value: 1.66e-108

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   2 TAANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKG 81
Cdd:PRK10261  306 TVVDGEPILQVRNLVTRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNG 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLrKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEF 161
Cdd:PRK10261  386 QRIDTLSPGKL-QALRRDIQFIFQDPYASLDPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAWRYPHEF 464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:PRK10261  465 SGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 242 LTGKFELYDNPLHPYTQALLSSVPVTRKrGSVKRERIVLKGELPSPanppkgcvFHTRCPVAKPIckeqipEFKEAAPSH 321
Cdd:PRK10261  545 IGPRRAVFENPQHPYTRKLMAAVPVADP-SRQRPQRVLLSDDLPSN--------IHLRGEEVAAV------SLQCVGPGH 609


                  ...
gi 2181075557 322 FVA 324
Cdd:PRK10261  610 YVA 612

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

5-283

1.96e-97

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 297.75 E-value: 1.96e-97

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKkyfpIRsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP----TEGQILFK 80
Cdd:COG4172     2 MSMPLLSVEDLS----VA---FGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDpaahPSGSILFD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDISNLSEEKLRKsVRKN-IQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLH-PSF-AGRY 157
Cdd:COG4172    75 GQDLLGLSERELRR-IRGNrIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPdPERrLDAY 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 158 PHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLG 237
Cdd:COG4172   154 PHQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQG 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2181075557 238 KMMELTGKFELYDNPLHPYTQALLSSVPVTRKRGSVKRERIVLKGE 283
Cdd:COG4172   234 EIVEQGPTAELFAAPQHPYTRKLLAAEPRGDPRPVPPDAPPLLEAR 279

SapF

COG4167

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

7-263

1.64e-96

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];

Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 286.35 E-value: 1.64e-96

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSGLFQRKvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ---- 82
Cdd:COG4167     2 SALLEVRNLSKTFKYRTGLFRRQ--QFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHkley 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 -DISNLSeeklrksvrKNIQMVFQDPFASLNPRKTLRSIIKEP--FNTHnmYTMRERNEKVEELLARVGLHPSFAGRYPH 159
Cdd:COG4167    80 gDYKYRC---------KHIRMIFQDPNTSLNPRLNIGQILEEPlrLNTD--LTAEEREERIFATLRLVGLLPEHANFYPH 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:COG4167   149 MLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEV 228

                         250       260
                  ....*....|....*....|....
gi 2181075557 240 MELTGKFELYDNPLHPYTQALLSS 263
Cdd:COG4167   229 VEYGKTAEVFANPQHEVTKRLIES 252

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

1-326

1.90e-85

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 260.43 E-value: 1.90e-85

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAANQETILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKS-TAGRTMIRLYKP--TEGQI 77
Cdd:PRK09473    4 LAQQQADALLDVKDLRVTFSTPDG-------DVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  78 LFKGQDISNLSEEKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLhPSFAGR- 156
Cdd:PRK09473   77 TFNGREILNLPEKELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKM-PEARKRm 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 157 --YPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:PRK09473  156 kmYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVM 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 235 YLGKMMELTGKFELYDNPLHPYTQALLSSVPvtrkrgsvkreRIVLKGE-LPS-PANP------PKGCVFHTRCPVAKPI 306
Cdd:PRK09473  236 YAGRTMEYGNARDVFYQPSHPYSIGLLNAVP-----------RLDAEGEsLLTiPGNPpnllrlPKGCPFQPRCPHAMEI 304

                         330       340
                  ....*....|....*....|
gi 2181075557 307 CKEQiPEFKEAAPSHFVACH 326
Cdd:PRK09473  305 CSSA-PPLEEFGPGRLRACF 323

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

3-262

6.83e-84

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 262.72 E-value: 6.83e-84

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDVKKYFPIRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYkPTEGQILFKGQ 82
Cdd:PRK15134  269 PEPASPLLDVEQLQVAFPIRKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLI-NSQGEIWFDGQ 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRkSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHN-MYTMRERNEKVEELLARVGLHPSFAGRYPHEF 161
Cdd:PRK15134  348 PLHNLNRRQLL-PVRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHQpTLSAAQREQQVIAVMEEVGLDPETRHRYPAEF 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:PRK15134  427 SGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVE 506

                         250       260
                  ....*....|....*....|.
gi 2181075557 242 LTGKFELYDNPLHPYTQALLS 262
Cdd:PRK15134  507 QGDCERVFAAPQQEYTRQLLA 527

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

8-268

2.92e-81

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 247.41 E-value: 2.92e-81

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpiRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNL 87
Cdd:TIGR02769   1 SLLEVRDVTHTY--RTGGLFGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 SEEKlRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQ 167
Cdd:TIGR02769  79 DRKQ-RRAFRRDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFE 247
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQ 237

                         250       260
                  ....*....|....*....|....*
gi 2181075557 248 LyDNPLHPYTQALLSSV----PVTR 268
Cdd:TIGR02769 238 L-LSFKHPAGRNLQSAVlpehPVRR 261

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

7-277

9.13e-78

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 246.35 E-value: 9.13e-78

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPirsglfqrkVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPT---EGQILFKGQD 83
Cdd:COG1123     2 TPLLEVRDLSVRYP---------GGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSEEKLRKSvrknIQMVFQDPFASLNPRkTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSG 163
Cdd:COG1123    73 LLELSEALRGRR----IGMVFQDPMTQLNPV-TVGDQIAEALENLGL-SRAEARARVLELLEAVGL-ERRLDRYPHQLSG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:COG1123   146 GQRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDG 225

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2181075557 244 GKFELYDNPlhpytqALLSSVPVTRKRGSVKRER 277
Cdd:COG1123   226 PPEEILAAP------QALAAVPRLGAARGRAAPA 253

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

34-326

7.55e-76

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 235.79 E-value: 7.55e-76

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLY----KPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFA 109
Cdd:PRK11022   21 RAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIdypgRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLhPSFAGR---YPHEFSGGQRQRIGIARALTLNPELIIADE 186
Cdd:PRK11022  101 SLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGI-PDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADE 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 187 PVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSVPv 266
Cdd:PRK11022  180 PTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPRHPYTQALLRALP- 258

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 267 trkRGSVKRERIV-LKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKeAAPSHFVACH 326
Cdd:PRK11022  259 ---EFAQDKARLAsLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALN-MLAGRQSKCH 315

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

8-268

2.18e-74

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 229.96 E-value: 2.18e-74

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpiRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNL 87
Cdd:PRK10419    2 TLLNVSGLSHHY--AHGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 SEEKlRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQ 167
Cdd:PRK10419   80 NRAQ-RKAFRRDIQMVFQDSISAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME-----L 242
Cdd:PRK10419  159 RVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVEtqpvgD 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 2181075557 243 TGKFElydnplHPYTQALLSSV----PVTR 268
Cdd:PRK10419  239 KLTFS------SPAGRVLQNAVlpafPVRR 262

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

9-265

4.46e-72

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 226.50 E-value: 4.46e-72

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:COG1135     1 MIELENLSKTFP-------TKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFASLNpRKT--------LRsIIKEPfnthnmytMRERNEKVEELLARVGLhPSFAGRYPHE 160
Cdd:COG1135    74 ERELRA-ARRKIGMIFQH-FNLLS-SRTvaenvalpLE-IAGVP--------KAEIRKRVAELLELVGL-SDKADAYPSQ 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:COG1135   141 LSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIV 220

                         250       260
                  ....*....|....*....|....*.
gi 2181075557 241 ElTGK-FELYDNPLHPYTQALLSSVP 265
Cdd:COG1135   221 E-QGPvLDVFANPQSELTRRFLPTVL 245

PRK15112

peptide ABC transporter ATP-binding protein SapF;

7-263

3.93e-69

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 216.58 E-value: 3.93e-69

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSGLFQRKvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISn 86
Cdd:PRK15112    2 ETLLEVRNLSKTFRYRTGWFRRQ--TVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLH- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLRKsvrKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQR 166
Cdd:PRK15112   79 FGDYSYRS---QRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKF 246
Cdd:PRK15112  156 QRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTA 235

                         250
                  ....*....|....*..
gi 2181075557 247 ELYDNPLHPYTQALLSS 263
Cdd:PRK15112  236 DVLASPLHELTKRLIAG 252

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

6-261

8.49e-69

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 214.84 E-value: 8.49e-69

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIS 85
Cdd:COG1127     2 SEPMIEVRNLTKSF-----------GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDIT 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  86 NLSEEKLRKsVRKNIQMVFQDP--FASLNprktlrsiIKE----PFNTHNMYTMRERNEKVEELLARVGLhPSFAGRYPH 159
Cdd:COG1127    71 GLSEKELYE-LRRRIGMLFQGGalFDSLT--------VFEnvafPLREHTDLSEAEIRELVLEKLELVGL-PGAADKMPS 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDvSIQAQVIN-LMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:COG1127   141 ELSGGMRKRVALARALALDPEILLYDEPTAGLD-PITSAVIDeLIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGK 219

                         250       260
                  ....*....|....*....|....
gi 2181075557 239 MMElTGKF-ELYDNPlHPYTQALL 261
Cdd:COG1127   220 IIA-EGTPeELLASD-DPWVRQFL 241

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

9-252

7.56e-68

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 212.06 E-value: 7.56e-68

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:cd03258     1 MIELKNVSKVFGDTGG-------KVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFASLNpRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQR 168
Cdd:cd03258    74 GKELRK-ARRRIGMIFQH-FNLLS-SRTVFENVALPLEIAGV-PKAEIEERVLELLELVGLE-DKADAYPAQLSGGQKQR 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFEL 248
Cdd:cd03258   149 VGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228


                  ....
gi 2181075557 249 YDNP 252
Cdd:cd03258   229 FANP 232

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

31-326

1.23e-67

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 214.77 E-value: 1.23e-67

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP----TEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQD 106
Cdd:COG4170    18 GRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDnwhvTADRFRWNGIDLLKLSPRERRKIIGREIAMIFQE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 107 PFASLNPRKTL-----RSIIKEPFNTHNMYTMRERNEKVEELLARVGL--HPSFAGRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:COG4170    98 PSSCLDPSAKIgdqliEAIPSWTFKGKWWQRFKWRKKRAIELLHRVGIkdHKDIMNSYPHELTEGECQKVMIAMAIANQP 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQA 259
Cdd:COG4170   178 RLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSPHHPYTKA 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 260 LLSSVPVTRKRGSVKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIP--EFKEaapsHFVACH 326
Cdd:COG4170   258 LLRSMPDFRQPLPHKSRLNTLPGSIPPLQHLPIGCRLGPRCPYAQKKCVETPRlrKIKG----HEFACH 322

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

8-265

3.04e-67

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 219.58 E-value: 3.04e-67

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpiRSGLFQRKVgdvkaVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYkPT------EGQILFKG 81
Cdd:PRK15134    4 PLLAIENLSVAF--RQQQTVRTV-----VNDVSLQIEAGETLALVGESGSGKSVTALSILRLL-PSppvvypSGDIRFHG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLRKsVRKN-IQMVFQDPFASLNPRKTLRSIIKEPFNTHNmyTMRERNEKVEEL--LARVGLHPSfAGR-- 156
Cdd:PRK15134   76 ESLLHASEQTLRG-VRGNkIAMIFQEPMVSLNPLHTLEKQLYEVLSLHR--GMRREAARGEILncLDRVGIRQA-AKRlt 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 157 -YPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:PRK15134  152 dYPHQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQ 231

                         250       260       270
                  ....*....|....*....|....*....|
gi 2181075557 236 LGKMMELTGKFELYDNPLHPYTQALLSSVP 265
Cdd:PRK15134  232 NGRCVEQNRAATLFSAPTHPYTQKLLNSEP 261

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

10-238

8.69e-64

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 201.58 E-value: 8.69e-64

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03261     1 IELRGLTKSF-----------GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKsVRKNIQMVFQDP--FASLnprkTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQ 167
Cdd:cd03261    70 AELYR-LRRRMGMLFQSGalFDSL----TVFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRG-AEDLYPAELSGGMKK 143

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDvSIQAQVI-NLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03261   144 RVALARALALDPELLLYDEPTAGLD-PIASGVIdDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGK 214

PRK15093

peptide ABC transporter ATP-binding protein SapD;

31-326

1.38e-60

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 196.56 E-value: 1.38e-60

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP----TEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQD 106
Cdd:PRK15093   18 GWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSPRERRKLVGHNVSMIFQE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 107 PFASLNP-----RKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGL--HPSFAGRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:PRK15093   98 PQSCLDPservgRQLMQNIPGWTYKGRWWQRFGWRKRRAIELLHRVGIkdHKDAMRSFPYELTEGECQKVMIAIALANQP 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQA 259
Cdd:PRK15093  178 RLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPHHPYTQA 257

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 260 LLSSVPVTRKRGSVKRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQiPEFKeAAPSHFVACH 326
Cdd:PRK15093  258 LIRAIPDFGSAMPHKSRLNTLPGAIPLLEHLPIGCRLGPRCPYAQRECIET-PRLT-GAKNHLYACH 322

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

11-264

4.95e-60

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 195.79 E-value: 4.95e-60

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  11 ELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEE 90
Cdd:PRK11153    3 ELKNISKVFPQGGR-------TIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEK 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  91 KLRKsVRKNIQMVFQDpFASLNPRkTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIG 170
Cdd:PRK11153   76 ELRK-ARRQIGMIFQH-FNLLSSR-TVFDNVALPLELAGT-PKAEIKARVTELLELVGL-SDKADRYPAQLSGGQKQRVA 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 171 IARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYD 250
Cdd:PRK11153  151 IARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFS 230

                         250
                  ....*....|....
gi 2181075557 251 NPLHPYTQALLSSV 264
Cdd:PRK11153  231 HPKHPLTREFIQST 244

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

6-256

8.09e-60

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 195.32 E-value: 8.09e-60

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFK 80
Cdd:COG3842     2 AMPALELENVSKRY-----------GDVTALDDVSLSIEPGEFVALLGPSGCGKTTllrmiAG-----FETPDSGRILLD 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDISNLSEEKlrksvRkNIQMVFQDpFAsLNPRKT--------LRsiikepfnthnmytMR-----ERNEKVEELLARV 147
Cdd:COG3842    66 GRDVTGLPPEK-----R-NVGMVFQD-YA-LFPHLTvaenvafgLR--------------MRgvpkaEIRARVAELLELV 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 148 GLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHD----LSv 223
Cdd:COG3842   124 GL-EGLADRYPHQLSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDqeeaLA- 201

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2181075557 224 vrhISDRVGVMYLGKMMELTGKFELYDNPLHPY 256
Cdd:COG3842   202 ---LADRIAVMNDGRIEQVGTPEEIYERPATRF 231

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

7-231

1.30e-59

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 190.64 E-value: 1.30e-59

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKG 81
Cdd:COG1136     2 SPLLELRNLTKSYGTGEG-------EVTALRGVSLSIEAGEFVAIVGPSGSGKSTllnilGG-----LDRPTSGEVLIDG 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLRKSVRKNIQMVFQDPFasLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEF 161
Cdd:COG1136    70 QDISSLSERELARLRRRHIGFVFQFFN--LLPELTALENVALPLLLAGV-SRKERRERARELLERVGL-GDRLDHRPSQL 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRV 231
Cdd:COG1136   146 SGGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAAR-ADRV 214

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

10-231

8.11e-59

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 188.47 E-value: 8.11e-59

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03255     1 IELKNLSKTY-------GGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVFQDPfaSLNPRKTLRSIIKEPFnthnMYT---MRERNEKVEELLARVGLhPSFAGRYPHEFSGGQR 166
Cdd:cd03255    74 KELAAFRRRHIGFVFQSF--NLLPDLTALENVELPL----LLAgvpKKERRERAEELLERVGL-GDRLNHYPSELSGGQQ 146

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRV 231
Cdd:cd03255   147 QRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRI 210

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

28-268

2.63e-58

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 189.01 E-value: 2.63e-58

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDp 107
Cdd:cd03294    32 KKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQS- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 FAsLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:cd03294   111 FA-LLPHRTVLENVAFGLEVQGV-PRAEREERAAEALELVGLEG-WEHKYPDELSGGMQQRVGLARALAVDPDILLMDEA 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSVPVT 267
Cdd:cd03294   188 FSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRGVDRA 267


                  .
gi 2181075557 268 R 268
Cdd:cd03294   268 K 268

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

8-251

5.70e-58

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 187.19 E-value: 5.70e-58

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNL 87
Cdd:COG3638     1 PMLELRNLSKRYP----------GGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTAL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 SEEKLRKsVRKNIQMVFQDPfaSLNPRKT---------------LRSIIkepfnthNMYTMRERnEKVEELLARVGLhPS 152
Cdd:COG3638    71 RGRALRR-LRRRIGMIFQQF--NLVPRLSvltnvlagrlgrtstWRSLL-------GLFPPEDR-ERALEALERVGL-AD 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 153 FAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVG 232
Cdd:COG3638   139 KAYQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRII 218

                         250       260
                  ....*....|....*....|....*..
gi 2181075557 233 VMYLGKMM------ELTGKF--ELYDN 251
Cdd:COG3638   219 GLRDGRVVfdgppaELTDAVlrEIYGG 245

PRK10261

glutathione transporter ATP-binding protein; Provisional

26-265

2.15e-57

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 195.46 E-value: 2.15e-57

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ----------DISNLSEEKLRKS 95
Cdd:PRK10261   22 FMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMllrrrsrqviELSEQSAAQMRHV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  96 VRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFA--GRYPHEFSGGQRQRIGIAR 173
Cdd:PRK10261  102 RGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTilSRYPHQLSGGMRQRVMIAM 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 174 ALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPL 253
Cdd:PRK10261  182 ALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQ 261

                         250
                  ....*....|..
gi 2181075557 254 HPYTQALLSSVP 265
Cdd:PRK10261  262 HPYTRALLAAVP 273

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

9-264

9.10e-57

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 183.66 E-value: 9.10e-57

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsNLS 88
Cdd:COG1126     1 MIEIENLHKSF-----------GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDS 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFaSLNPRKT-LRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQ 167
Cdd:COG1126    69 KKDINK-LRRKVGMVFQQ-F-NLFPHLTvLENVTLAPIKVKKM-SKAEAEERAMELLERVGL-ADKADAYPAQLSGGQQQ 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFE 247
Cdd:COG1126   144 RVAIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEE 222

                         250
                  ....*....|....*..
gi 2181075557 248 LYDNPLHPYTQALLSSV 264
Cdd:COG1126   223 FFENPQHERTRAFLSKV 239

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

10-252

1.43e-55

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 180.96 E-value: 1.43e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03295     1 IEFENVTKRYG----------GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDP 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVfqdpfaSLNPRKTLR-------SIIKEPfnthnmytMRERNEKVEELLARVGLHP-SFAGRYPHEF 161
Cdd:cd03295    71 VELRRKIGYVIQQI------GLFPHMTVEenialvpKLLKWP--------KEKIRERADELLALVGLDPaEFADRYPHEL 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:cd03295   137 SGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQ 216

                         250
                  ....*....|.
gi 2181075557 242 LTGKFELYDNP 252
Cdd:cd03295   217 VGTPDEILRSP 227

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

1-234

1.54e-55

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 181.44 E-value: 1.54e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAAnqETILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEG 75
Cdd:COG1116     1 MSAA--APALELRGVSKRFPTGGG-------GVTALDDVSLTVAAGEFVALVGPSGCGKSTllrliAG-----LEKPTSG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  76 QILFKGQDISNLSEEklrksvrknIQMVFQDPfaSLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPsFAG 155
Cdd:COG1116    67 EVLVDGKPVTGPGPD---------RGVVFQEP--ALLPWLTVLDNVALGLELRGV-PKAERRERARELLELVGLAG-FED 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 156 RYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV----SIQaqviNLMEELQEEFNLTYLFISHDLS-VVRhISDR 230
Cdd:COG1116   134 AYPHQLSGGMRQRVAIARALANDPEVLLMDEPFGALDAltreRLQ----DELLRLWQETGKTVLFVTHDVDeAVF-LADR 208


                  ....
gi 2181075557 231 VGVM 234
Cdd:COG1116   209 VVVL 212

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

10-234

2.25e-55

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 179.59 E-value: 2.25e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlse 89
Cdd:cd03293     1 LEVRNVSKTYG-------GGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT---- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklrkSVRKNIQMVFQDPfaSLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRI 169
Cdd:cd03293    70 -----GPGPDRGYVFQQD--ALLPWLTVLDNVALGLELQGV-PKAEARERAEELLELVGL-SGFENAYPHQLSGGMRQRV 140

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:cd03293   141 ALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

10-238

3.18e-55

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 178.87 E-value: 3.18e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03259     1 LELKGLSKTY-----------GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EklrksvRKNIQMVFQDPfaSLNPRKTLRSIIKEPFNTHNMYTmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRI 169
Cdd:cd03259    70 E------RRNIGMVFQDY--ALFPHLTVAENIAFGLKLRGVPK-AEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRV 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03259   140 ALARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGR 208

OpuBA

COG1125

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...

11-234

3.90e-55

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 181.83 E-value: 3.90e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  11 ELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRtMI-RLYKPTEGQILFKGQDISNLSE 89
Cdd:COG1125     3 EFENVTKRYP----------DGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLR-MInRLIEPTSGRILIDGEDIRDLDP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKS---------------VRKNIQMVfqdpfaslnPRktlrsIIKEPfnthnmytmRER-NEKVEELLARVGLHPS- 152
Cdd:COG1125    72 VELRRRigyviqqiglfphmtVAENIATV---------PR-----LLGWD---------KERiRARVDELLELVGLDPEe 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 153 FAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVG 232
Cdd:COG1125   129 YRDRYPHELSGGQQQRVGVARALAADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHDIDEALKLGDRIA 208


                  ..
gi 2181075557 233 VM 234
Cdd:COG1125   209 VM 210

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

10-238

5.71e-54

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 174.68 E-value: 5.71e-54

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlSE 89
Cdd:cd03229     1 LELKNVSKRY-----------GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLT--DL 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVFQDPfaSLNPRKTLRSIIKEPFnthnmytmrernekveellarvglhpsfagryphefSGGQRQRI 169
Cdd:cd03229    68 EDELPPLRRRIGMVFQDF--ALFPHLTVLENIALGL------------------------------------SGGQQQRV 109

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03229   110 ALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

10-240

6.14e-53

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 173.67 E-value: 6.14e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlse 89
Cdd:COG1122     1 IELENLSFSYP----------GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDIT---- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVFQDP----FASlnprktlrSIIKE----PFNTHnmYTMRERNEKVEELLARVGLHpSFAGRYPHEF 161
Cdd:COG1122    67 KKNLRELRRKVGLVFQNPddqlFAP--------TVEEDvafgPENLG--LPREEIRERVEEALELVGLE-HLADRPPHEL 135

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:COG1122   136 SGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLDDGRIV 213

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

10-234

9.42e-53

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 172.71 E-value: 9.42e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsNLSE 89
Cdd:cd03262     1 IEIKNLHKSF-----------GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-TDDK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKsVRKNIQMVFQDpFaSLNPRKT-LRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQR 168
Cdd:cd03262    69 KNINE-LRQKVGMVFQQ-F-NLFPHLTvLENITLAPIKVKGM-SKAEAEERALELLEKVGL-ADKADAYPAQLSGGQQQR 143

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:cd03262   144 VAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFM 208

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

10-239

2.65e-52

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 172.17 E-value: 2.65e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:COG1131     1 IEVRGLTKRY-----------GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPA 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EklrksVRKNIQMVFQDP--FASLNPRKTLRSIIKepfnthnMYTM--RERNEKVEELLARVGLHPsFAGRYPHEFSGGQ 165
Cdd:COG1131    70 E-----VRRRIGYVPQEPalYPDLTVRENLRFFAR-------LYGLprKEARERIDELLELFGLTD-AADRKVGTLSGGM 136

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 166 RQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:COG1131   137 KQRLGLALALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRI 209

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

10-241

7.90e-52

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 170.82 E-value: 7.90e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK-----PTEGQILFKGQDI 84
Cdd:cd03260     1 IELRDLNVYY-----------GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDI 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLrkSVRKNIQMVFQDPfaslNP-RKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGR-YPHEFS 162
Cdd:cd03260    70 YDLDVDVL--ELRRRVGMVFQKP----NPfPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRlHALGLS 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDvSIQAQVI-NLMEELQEEfnLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:cd03260   144 GGQQQRLCLARALANEPEVLLLDEPTSALD-PISTAKIeELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVE 220

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

26-238

2.96e-51

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 168.80 E-value: 2.96e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQ 105
Cdd:cd03225     7 FSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLS----LKELRRKVGLVFQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPFASL-NPrkTLRSIIKepFNTHNMYTMR-ERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:cd03225    83 NPDDQFfGP--TVEEEVA--FGLENLGLPEeEIEERVEEALELVGLE-GLRDRSPFTLSGGQKQRVAIAGVLAMDPDILL 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03225   158 LDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDGK 211

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

24-249

5.71e-51

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 168.90 E-value: 5.71e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  24 GLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRkSVRKNIQMV 103
Cdd:cd03256     5 NLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALR-QLRRQIGMI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 104 FQDP-------------FASLNPRKTLRSIIkepfnthNMYTMRERnEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIG 170
Cdd:cd03256    84 FQQFnlierlsvlenvlSGRLGRRSTWRSLF-------GLFPKEEK-QRALAALERVGLL-DKAYQRADQLSGGQQQRVA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 171 IARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDR-VG-----VMYLGKMMELTG 244
Cdd:cd03256   155 IARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRiVGlkdgrIVFDGPPAELTD 234


                  ....*..
gi 2181075557 245 KF--ELY 249
Cdd:cd03256   235 EVldEIY 241

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

9-231

5.92e-50

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 166.32 E-value: 5.92e-50

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:TIGR02315   1 MLEVENLSKVYP----------NGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFASLNPRKTLRSIIKEPFNTHNMYTM------RERNEKVEELLARVGLhPSFAGRYPHEFS 162
Cdd:TIGR02315  71 GKKLRK-LRRRIGMIFQH-YNLIERLTVLENVLHGRLGYKPTWRSllgrfsEEDKERALSALERVGL-ADKAYQRADQLS 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRV 231
Cdd:TIGR02315 148 GGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRI 216

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

10-231

5.47e-49

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 162.68 E-value: 5.47e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVkkyfpirsglfQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:COG4619     1 LELEGL-----------SFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRkniqMVFQDPFAslnPRKTLRSIIKEPFNTHNMYTMRERnekVEELLARVGLHPSFAGRYPHEFSGGQRQRI 169
Cdd:COG4619    70 PEWRRQVA----YVPQEPAL---WGGTVRDNLPFPFQLRERKFDRER---ALELLERLGLPPDILDKPVERLSGGERQRL 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRV 231
Cdd:COG4619   140 ALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRV 201

LivG

COG0411

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...

7-238

6.19e-49

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];

Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 164.06 E-value: 6.19e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrtMIRL----YKPTEGQILFKGQ 82
Cdd:COG0411     2 DPLLEVRGLTKRF-----------GGLVAVDDVSLEVERGEIVGLIGPNGAGKTT----LFNLitgfYRPTSGRILFDGR 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLrksVRKNIQMVFQDP--FASL----N-----PRKTLRSIIKEPFNT-HNMYTMRERNEKVEELLARVGLH 150
Cdd:COG0411    67 DITGLPPHRI---ARLGIARTFQNPrlFPELtvleNvlvaaHARLGRGLLAALLRLpRARREEREARERAEELLERVGLA 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 151 PsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDR 230
Cdd:COG0411   144 D-RADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADR 222


                  ....*...
gi 2181075557 231 VGVMYLGK 238
Cdd:COG0411   223 IVVLDFGR 230

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

4-264

1.92e-48

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 163.17 E-value: 1.92e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   4 ANQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMirlykPTEGQIL 78
Cdd:PRK11701    1 MMDQPLLSVRGLTKLY-----------GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTllnalSARLA-----PDAGEVH 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  79 FKGQ-----DISNLSEEKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPfnthnMYTMRERN-----EKVEELLARVG 148
Cdd:PRK11701   65 YRMRdgqlrDLYALSEAERRRLLRTEWGFVHQHPRDGLRMQVSAGGNIGER-----LMAVGARHygdirATAGDWLERVE 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 149 LHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHIS 228
Cdd:PRK11701  140 IDAARIDDLPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLA 219

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2181075557 229 DRVGVMYLGKMME--LTGKfeLYDNPLHPYTQALLSSV 264
Cdd:PRK11701  220 HRLLVMKQGRVVEsgLTDQ--VLDDPQHPYTQLLVSSV 255

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

10-240

5.64e-48

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 161.07 E-value: 5.64e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03219     1 LEVRGLTKRF-----------GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLrksVRKNIQMVFQDP--FASL----NPRKTLRSIIKEPFNTH-NMYTMRERNEKVEELLARVGLHPsFAGRYPHEFS 162
Cdd:cd03219    70 HEI---ARLGIGRTFQIPrlFPELtvleNVMVAAQARTGSGLLLArARREEREARERAEELLERVGLAD-LADRPAGELS 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQeEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:cd03219   146 YGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELR-ERGITVLLVEHDMDVVMSLADRVTVLDQGRVI 222

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

9-245

9.51e-48

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 160.22 E-value: 9.51e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:COG2884     1 MIRFENVSKRYP----------GGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLK 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFaSLNPRKT--------LRSIIKEPfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHE 160
Cdd:COG2884    71 RREIPY-LRRRIGVVFQD-F-RLLPDRTvyenvalpLRVTGKSR---------KEIRRRVREVLDLVGLS-DKAKALPHE 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:COG2884   138 LSGGEQQRVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRR-GTTVLIATHDLELVDRMPKRVLELEDGRLV 216


                  ....*
gi 2181075557 241 ELTGK 245
Cdd:COG2884   217 RDEAR 221

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

36-187

1.71e-47

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 157.04 E-value: 1.71e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFasLNPRK 115
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE----RKSLRKEIGYVFQDPQ--LFPRL 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 116 TLRSIIKEPFNTHNMYTmRERNEKVEELLARVGL---HPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:pfam00005  75 TVRENLRLGLLLKGLSK-REKDARAEEALEKLGLgdlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEP 148

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

10-252

2.25e-47

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 159.32 E-value: 2.25e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03300     1 IELENVSKFY-----------GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKlrksvrKNIQMVFQDpFAsLNPRKTLRSIIKEPFnthnmyTMR-----ERNEKVEELLARVGLHpSFAGRYPHEFSGG 164
Cdd:cd03300    70 HK------RPVNTVFQN-YA-LFPHLTVFENIAFGL------RLKklpkaEIKERVAEALDLVQLE-GYANRKPSQLSGG 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTG 244
Cdd:cd03300   135 QQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214


                  ....*...
gi 2181075557 245 KFELYDNP 252
Cdd:cd03300   215 PEEIYEEP 222

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

10-293

2.28e-47

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 162.93 E-value: 2.28e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:COG3839     4 LELENVSKSY-----------GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKlRksvrkNIQMVFQDpFAsLNPRKTLRsiikepfntHNM-YTMR-------ERNEKVEELLARVGLHPsFAGRYPHEF 161
Cdd:COG3839    73 KD-R-----NIAMVFQS-YA-LYPHMTVY---------ENIaFPLKlrkvpkaEIDRRVREAAELLGLED-LLDRKPKQL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHD----LSvvrhISDRVGVMYLG 237
Cdd:COG3839   135 SGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMT----LADRIAVMNDG 210

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 238 KMMELtGK-FELYDNPLHPYTQALLSSVPVTRKRGSVKRERIVLKG---ELPSPANPPKG 293
Cdd:COG3839   211 RIQQV-GTpEELYDRPANLFVAGFIGSPPMNLLPGTVEGGGVRLGGvrlPLPAALAAAAG 269

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

10-295

2.80e-47

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 162.62 E-value: 2.80e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQDI 84
Cdd:COG1118     3 IEVRNISKRF-----------GSFTLLDDVSLEIASGELVALLGPSGSGKTTllriiAG-----LETPDSGRIVLNGRDL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 -SNLseeklrkSVRK-NIQMVFQDP-------------FAsLNPRKTLRSIIKepfnthnmytmrernEKVEELLARVGL 149
Cdd:COG1118    67 fTNL-------PPRErRVGFVFQHYalfphmtvaeniaFG-LRVRPPSKAEIR---------------ARVEELLELVQL 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 hPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISD 229
Cdd:COG1118   124 -EGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELAD 202

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 230 RVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSV---PVTRKRGSVKRERIVLKGELPSPANPPKGCV 295
Cdd:COG1118   203 RVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVnvlRGRVIGGQLEADGLTLPVAEPLPDGPAVAGV 271

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

10-238

6.31e-47

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 156.00 E-value: 6.31e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKkyfpirsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSe 89
Cdd:cd03228     1 IEFKNVS---------FSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLD- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklRKSVRKNIQMVFQDPFasLnprktlrsiikepFNThnmyTMRErNekveeLLarvglhpsfagryphefSGGQRQRI 169
Cdd:cd03228    71 ---LESLRKNIAYVPQDPF--L-------------FSG----TIRE-N-----IL-----------------SGGQRQRI 105

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGK 238
Cdd:cd03228   106 AIARALLRDPPILILDEATSALDPETEALILEALRALAK--GKTVIVIAHRLSTIRD-ADRIIVLDDGR 171

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

31-240

1.18e-46

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 158.28 E-value: 1.18e-46

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFAS 110
Cdd:COG1120    12 GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLS----RRELARRIAYVPQEPPAP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LN------------PRKTlrsiikePFNTHNmytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:COG1120    88 FGltvrelvalgryPHLG-------LFGRPS----AEDREAVEEALERTGLEH-LADRPVDELSGGERQRVLIARALAQE 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:COG1120   156 PPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIV 217

3a0106s01

TIGR00968

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

28-266

2.16e-45

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]

Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 154.57 E-value: 2.16e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrksvRKNIQMVFQDp 107
Cdd:TIGR00968   8 KRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQDATRVHAR------DRKIGFVFQH- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 fASLNPRKTLRSiikepfNTHNMYTMRERN-----EKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELI 182
Cdd:TIGR00968  81 -YALFKHLTVRD------NIAFGLEIRKHPkakikARVEELLELVQLE-GLGDRYPNQLSGGQRQRVALARALAVEPQVL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 183 IADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLS 262
Cdd:TIGR00968 153 LLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLG 232


                  ....
gi 2181075557 263 SVPV 266
Cdd:TIGR00968 233 EVNV 236

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

10-256

1.15e-44

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 152.49 E-value: 1.15e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03296     3 IEVRNVSKRF-----------GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKlrksvrKNIQMVFQDpfASLNPRKTLRSII------KEPFNTHNMYTMRERnekVEELLARVGLHpSFAGRYPHEFSG 163
Cdd:cd03296    72 QE------RNVGFVFQH--YALFRHMTVFDNVafglrvKPRSERPPEAEIRAK---VHELLKLVQLD-WLADRYPAQLSG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:cd03296   140 GQRQRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVG 219

                         250
                  ....*....|...
gi 2181075557 244 GKFELYDNPLHPY 256
Cdd:cd03296   220 TPDEVYDHPASPF 232

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

10-239

1.61e-44

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 152.32 E-value: 1.61e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlse 89
Cdd:COG4555     2 IEVENLSKKY-----------GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDV----- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVFQDPFasLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRI 169
Cdd:COG4555    66 RKEPREARRQIGVLPDERG--LYDRLTVRENIRYFAELYGL-FDEELKKRIEELIELLGL-EEFLDRRVGELSTGMKKKV 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:COG4555   142 ALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKKE-GKTVLFSSHIMQEVEALCDRVVILHKGKV 210

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

10-239

1.86e-44

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 149.86 E-value: 1.86e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlse 89
Cdd:cd03230     1 IEVRNLSKRY-----------GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK---- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eKLRKSVRKNIQMVFQDPfaSLNPRKTlrsiikepfnthnmytmrernekVEELLarvglhpsfagryphEFSGGQRQRI 169
Cdd:cd03230    66 -KEPEEVKRRIGYLPEEP--SLYENLT-----------------------VRENL---------------KLSGGMKQRL 104

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03230   105 ALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

31-241

5.26e-44

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 160.38 E-value: 5.26e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFas 110
Cdd:COG2274   486 DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQID----PASLRRQIGVVLQDVF-- 559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 lnprktlrsiikePFNThnmyTMRErN----------EKVEELLARVGLHpSFAGRYPH-----------EFSGGQRQRI 169
Cdd:COG2274   560 -------------LFSG----TIRE-NitlgdpdatdEEIIEAARLAGLH-DFIEALPMgydtvvgeggsNLSGGQRQRL 620

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMME 241
Cdd:COG2274   621 AIARALLRNPRILILDEATSALDAETEAIILENLRRLLK--GRTVIIIAHRLSTIRL-ADRIIVLDKGRIVE 689

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

27-238

1.03e-43

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 147.39 E-value: 1.03e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  27 QRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKsvrkNIQMVFQd 106
Cdd:cd00267     6 SFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRR----RIGYVPQ- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 107 pfaslnprktlrsiikepfnthnmytmrernekveellarvglhpsfagrypheFSGGQRQRIGIARALTLNPELIIADE 186
Cdd:cd00267    81 ------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 187 PVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd00267   107 PTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

9-241

1.81e-43

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 149.04 E-value: 1.81e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:TIGR02211   1 LLKCENLGKRY-------QEGKLDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGQSLSKLS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKSVRKNIQMVFQdpFASLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPSfAGRYPHEFSGGQRQR 168
Cdd:TIGR02211  74 SNERAKLRNKKLGFIYQ--FHHLLPDFTALENVAMPLLIGKK-SVKEAKERAYEMLEKVGLEHR-INHRPSELSGGERQR 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHIsDRVGVMYLGKMME 241
Cdd:TIGR02211 150 VAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKKL-DRVLEMKDGQLFN 221

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

29-239

5.22e-43

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 146.43 E-value: 5.22e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQdpf 108
Cdd:cd03214     8 GYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLS----PKELARKIAYVPQ--- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 aslnprktlrsiikepfnthnmytmrernekveeLLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:cd03214    81 ----------------------------------ALELLGLA-HLADRPFNELSGGERQRVLLARALAQEPPILLLDEPT 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 189 SALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03214   126 SHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRI 176

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

10-242

5.33e-43

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 147.40 E-value: 5.33e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03301     1 VELENVTKRF-----------GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKlrksvrKNIQMVFQDpFAsLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRI 169
Cdd:cd03301    70 KD------RDIAMVFQN-YA-LYPHMTVYDNIAFGLKLRKV-PKDEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRV 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMEL 242
Cdd:cd03301   140 ALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQI 212

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

6-252

1.46e-42

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 150.25 E-value: 1.46e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIS 85
Cdd:PRK11432    3 QKNFVVLKNITKRF-----------GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  86 NLSEEKlrksvrKNIQMVFQD----PFASL--NPRKTLR--SIIKEpfnthnmytmrERNEKVEELLARVGLhPSFAGRY 157
Cdd:PRK11432   72 HRSIQQ------RDICMVFQSyalfPHMSLgeNVGYGLKmlGVPKE-----------ERKQRVKEALELVDL-AGFEDRY 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 158 PHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLG 237
Cdd:PRK11432  134 VDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKG 213

                         250
                  ....*....|....*
gi 2181075557 238 KMMELTGKFELYDNP 252
Cdd:PRK11432  214 KIMQIGSPQELYRQP 228

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

28-252

1.58e-42

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 147.10 E-value: 1.58e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKaVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKlrksvrKNIQMVFQDp 107
Cdd:cd03299     8 KDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK------RDISYVPQN- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 fASLNPRKTLRSIIKepfnthnmYTMRERNEKVEELLARVGLHPSFAG------RYPHEFSGGQRQRIGIARALTLNPEL 181
Cdd:cd03299    80 -YALFPHMTVYKNIA--------YGLKKRKVDKKEIERKVLEIAEMLGidhllnRKPETLSGGEQQRVAIARALVVNPKI 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 182 IIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNP 252
Cdd:cd03299   151 LLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKP 221

CP_lyasePhnK

TIGR02323

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...

31-264

1.89e-42

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]

Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 147.28 E-value: 1.89e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQD-----ISNLSEEKLRKSVRKNIQMVFQ 105
Cdd:TIGR02323  14 GGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSgaeleLYQLSEAERRRLMRTEWGFVHQ 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dpfaslNPRKTLR-------SIIKEPFNTHNMYTMRERnEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:TIGR02323  94 ------NPRDGLRmrvsagaNIGERLMAIGARHYGNIR-ATAQDWLEEVEIDPTRIDDLPRAFSGGMQQRLQIARNLVTR 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQ 258
Cdd:TIGR02323 167 PRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQHPYTQ 246


                  ....*.
gi 2181075557 259 ALLSSV 264
Cdd:TIGR02323 247 LLVSSI 252

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

10-239

5.91e-42

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 142.95 E-value: 5.91e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSe 89
Cdd:cd03216     1 LELRGITKRF-----------GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAS- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 ekLRKSVRKNIQMVFQdpfaslnprktlrsiikepfnthnmytmrernekveellarvglhpsfagrypheFSGGQRQRI 169
Cdd:cd03216    69 --PRDARRAGIAMVYQ-------------------------------------------------------LSVGERQMV 91

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03216    92 EIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQ-GVAVIFISHRLDEVFEIADRVTVLRDGRV 160

ECF_ATPase_2

TIGR04521

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...

34-238

6.76e-42

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 146.44 E-value: 6.76e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTagrtMIR----LYKPTEGQILFKGQDISNLSEEKLrKSVRKNIQMVFQDP-- 107
Cdd:TIGR04521  19 KALDDVSLTIEDGEFVAIIGHTGSGKST----LIQhlngLLKPTSGTVTIDGRDITAKKKKKL-KDLRKKVGLVFQFPeh 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 --FAslnprktlRSIIKE-PFNTHNM-YTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:TIGR04521  94 qlFE--------ETVYKDiAFGPKNLgLSEEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVLAMEPEVLI 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:TIGR04521 166 LDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGK 220

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

29-268

9.75e-42

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 149.41 E-value: 9.75e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDpF 108
Cdd:PRK10070   37 KTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQS-F 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 AsLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:PRK10070  116 A-LMPHMTVLDNTAFGMELAGI-NAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAF 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 189 SALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSVPVTR 268
Cdd:PRK10070  193 SALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQ 272

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-262

9.83e-42

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 145.56 E-value: 9.83e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAA--NQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK--P---T 73
Cdd:COG1117     1 MTAPasTLEPKIEVRNLNVYY-----------GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDliPgarV 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  74 EGQILFKGQDIS----NLSEeklrksVRKNIQMVFQDPfaslNP-RKTlrsiIKE----PFNTHNMYTMRERNEKVEELL 144
Cdd:COG1117    70 EGEILLDGEDIYdpdvDVVE------LRRRVGMVFQKP----NPfPKS----IYDnvayGLRLHGIKSKSELDEIVEESL 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 145 ARVG--------LHPSfagryPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFnlTYLF 216
Cdd:COG1117   136 RKAAlwdevkdrLKKS-----ALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDY--TIVI 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2181075557 217 ISHDLSVVRHISDRVGVMYLGKMMEL--TGK-FElydNPLHPYTQALLS 262
Cdd:COG1117   209 VTHNMQQAARVSDYTAFFYLGELVEFgpTEQiFT---NPKDKRTEDYIT 254

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

31-234

1.42e-41

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 152.24 E-value: 1.42e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFas 110
Cdd:COG1132   351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLT----LESLRRQIGVVPQDTF-- 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LnprktlrsiikepFNThnmyTMRErN----------EKVEELLARVGLHPsFAGRYPH-----------EFSGGQRQRI 169
Cdd:COG1132   425 L-------------FSG----TIRE-NirygrpdatdEEVEEAAKAAQAHE-FIEALPDgydtvvgergvNLSGGQRQRI 485

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVM 234
Cdd:COG1132   486 AIARALLKDPPILILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTIRN-ADRILVL 547

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

40-234

5.29e-41

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 142.43 E-value: 5.29e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSLK-----KGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdISNLSEEKLRKSVRK-NIQMVFQDpfASLNP 113
Cdd:cd03297    12 DFTLKidfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGT-VLFDSRKKINLPPQQrKIGLVFQQ--YALFP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNTHNMYTMRERnekVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:cd03297    89 HLNVRENLAFGLKRKRNREDRIS---VDELLDLLGLDH-LLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDR 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2181075557 194 SIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:cd03297   165 ALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVM 205

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

28-239

1.65e-40

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 141.35 E-value: 1.65e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrksVRKNIQMVFQDP 107
Cdd:cd03265     8 KKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPRE-----VRRRIGIVFQDL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 faSLNPRKTLRsiikepfntHNMYTM--------RERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:cd03265    83 --SVDDELTGW---------ENLYIHarlygvpgAERRERIDELLDFVGLL-EAADRLVKTYSGGMRRRLEIARSLVHRP 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03265   151 EVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRI 210

PRK10619

histidine ABC transporter ATP-binding protein HisP;

26-262

5.13e-40

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 141.26 E-value: 5.13e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIS---------NLSEEKLRKSV 96
Cdd:PRK10619   11 LHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlKVADKNQLRLL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  97 RKNIQMVFQDpFASLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALT 176
Cdd:PRK10619   91 RTRLTMVFQH-FNLWSHMTVLENVMEAPIQVLGL-SKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARALA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 177 LNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPY 256
Cdd:PRK10619  169 MEPEVLLFDEPTSALDPELVGEVLRIMQQLAEE-GKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPR 247


                  ....*.
gi 2181075557 257 TQALLS 262
Cdd:PRK10619  248 LQQFLK 253

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

1-243

6.14e-40

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 140.26 E-value: 6.14e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAANQeTILELRDVKKYFPIRSGlfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEG 75
Cdd:COG4181     1 MSSSSA-PIIELRGLTKTVGTGAG-------ELTILKGISLEVEAGESVAIVGASGSGKSTllgllAG-----LDRPTSG 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  76 QILFKGQDISNLSEE---KLRksvRKNIQMVFQDpFaSLNPRKT----------LRSiikepfnthnmytMRERNEKVEE 142
Cdd:COG4181    68 TVRLAGQDLFALDEDaraRLR---ARHVGFVFQS-F-QLLPTLTalenvmlpleLAG-------------RRDARARARA 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 143 LLARVGLhpsfAGR---YPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISH 219
Cdd:COG4181   130 LLERVGL----GHRldhYPAQLSGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTH 205

                         250       260
                  ....*....|....*....|....
gi 2181075557 220 DLSVVRHiSDRVGVMYLGKMMELT 243
Cdd:COG4181   206 DPALAAR-CDRVLRLRAGRLVEDT 228

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

5-241

7.59e-40

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 141.31 E-value: 7.59e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKkyfpirsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDi 84
Cdd:PRK13635    1 MKEEIIRVEHIS---------FRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMV- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 snLSEEKLRKsVRKNIQMVFQDP---FASlnprKTLRSIIKepFNTHNMYTMRERN-EKVEELLARVGLHpSFAGRYPHE 160
Cdd:PRK13635   71 --LSEETVWD-VRRQVGMVFQNPdnqFVG----ATVQDDVA--FGLENIGVPREEMvERVDQALRQVGME-DFLNREPHR 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRVGVMYLGKMM 240
Cdd:PRK13635  141 LSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEIL 219


                  .
gi 2181075557 241 E 241
Cdd:PRK13635  220 E 220

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

1-252

8.91e-40

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 143.55 E-value: 8.91e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAANQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK 80
Cdd:PRK09452    6 KQPSSLSPLVELRGISKSF-----------DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDISNLSEEKlrksvrKNIQMVFQDpFAsLNPRKTLRSII-------KEPFnthnmytmRERNEKVEELLARVGLHpSF 153
Cdd:PRK09452   75 GQDITHVPAEN------RHVNTVFQS-YA-LFPHMTVFENVafglrmqKTPA--------AEITPRVMEALRMVQLE-EF 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 154 AGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGV 233
Cdd:PRK09452  138 AQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVV 217

                         250
                  ....*....|....*....
gi 2181075557 234 MYLGKMMELTGKFELYDNP 252
Cdd:PRK09452  218 MRDGRIEQDGTPREIYEEP 236

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

31-231

1.03e-39

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 139.84 E-value: 1.03e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlseEKLRKSV-----RKNIQMVFq 105
Cdd:COG1121    17 GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP-----RRARRRIgyvpqRAEVDWDF- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dPF-------ASLNPRKTLRSIIKepfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:COG1121    91 -PItvrdvvlMGRYGRRGLFRRPS-----------RADREAVDEALERVGLE-DLADRPIGELSGGQQQRVLLARALAQD 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:COG1121   158 PDLLLLDEPFAGVDAATEEALYELLRELRRE-GKTILVVTHDLGAVREYFDRV 209

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

32-263

2.92e-39

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 139.06 E-value: 2.92e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP----TEGQILFKGQDISnlsEEKLRKsvrKNIQMVFQDP 107
Cdd:PRK10418   15 AQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAgvrqTAGRVLLDGKPVA---PCALRG---RKIATIMQNP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 FASLNPRKTLRSiikepfntHNMYTMRER-----NEKVEELLARVGLH--PSFAGRYPHEFSGGQRQRIGIARALTLNPE 180
Cdd:PRK10418   89 RSAFNPLHTMHT--------HARETCLALgkpadDATLTAALEAVGLEnaARVLKLYPFEMSGGMLQRMMIALALLCEAP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 181 LIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQAL 260
Cdd:PRK10418  161 FIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSL 240


                  ...
gi 2181075557 261 LSS 263
Cdd:PRK10418  241 VSA 243

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

31-247

4.52e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 144.90 E-value: 4.52e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDP--F 108
Cdd:COG4988   348 GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPA----SWRRQIAWVPQNPylF 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASlnprkTLRSIIKepfnthnMYTMRERNEKVEELLARVGLHpSFAGRYPH-------E----FSGGQRQRIGIARALTL 177
Cdd:COG4988   424 AG-----TIRENLR-------LGRPDASDEELEAALEAAGLD-EFVAALPDgldtplgEggrgLSGGQAQRLALARALLR 490

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 178 NPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMElTGKFE 247
Cdd:COG4988   491 DAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLAQ-ADRILVLDDGRIVE-QGTHE 556

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

31-241

7.66e-39

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 137.45 E-value: 7.66e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ--DISNLSEEKLRKSVRKNIQMVFQDpf 108
Cdd:PRK11124   13 GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPSDKAIRELRRNVGMVFQQ-- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKT-LRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:PRK11124   91 YNLWPHLTvQQNLIEAPCRVLGL-SKDQALARAEKLLERLRLKP-YADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEP 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:PRK11124  169 TAALDPEITAQIVSIIRELAET-GITQVIVTHEVEVARKTASRVVYMENGHIVE 221

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

31-247

9.22e-39

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 136.97 E-value: 9.22e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFas 110
Cdd:cd03254    14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDIS----RKSLRSMIGVVLQDTF-- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRkTLRSIIKepfnthnMYTMRERNEKVEELLARVGLHPsFAGRYP-----------HEFSGGQRQRIGIARALTLNP 179
Cdd:cd03254    88 LFSG-TIMENIR-------LGRPNATDEEVIEAAKEAGAHD-FIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMElTGKFE 247
Cdd:cd03254   159 KILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIKN-ADKILVLDDGKIIE-EGTHD 222

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

9-264

1.62e-38

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 136.76 E-value: 1.62e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsNLS 88
Cdd:PRK09493    1 MIEFKNVSKHF-----------GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKV-NDP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKsVRKNIQMVFQDpFaSLNPRKT-LRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQ 167
Cdd:PRK09493   69 KVDERL-IRQEAGMVFQQ-F-YLFPHLTaLENVMFGPLRVRGA-SKEEAEKQARELLAKVGL-AERAHHYPSELSGGQQQ 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFE 247
Cdd:PRK09493  144 RVAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEE-GMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQV 222

                         250
                  ....*....|....*..
gi 2181075557 248 LYDNPLHPYTQALLSSV 264
Cdd:PRK09493  223 LIKNPPSQRLQEFLQHV 239

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

7-234

2.10e-38

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 142.08 E-value: 2.10e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPirsglfqrkvGdVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKG 81
Cdd:COG1129     2 EPLLEMRGISKSFG----------G-VKALDGVSLELRPGEVHALLGENGAGKSTlmkilSG-----VYQPDSGEILLDG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSeekLRKSVRKNIQMVFQDP------------FASLNPRKtlRSIIKEpfnthnmytmRERNEKVEELLARVGL 149
Cdd:COG1129    66 EPVRFRS---PRDAQAAGIAIIHQELnlvpnlsvaeniFLGREPRR--GGLIDW----------RAMRRRARELLARLGL 130

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 HPSfagryPH----EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVR 225
Cdd:COG1129   131 DID-----PDtpvgDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQ-GVAIIYISHRLDEVF 204


                  ....*....
gi 2181075557 226 HISDRVGVM 234
Cdd:COG1129   205 EIADRVTVL 213

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

4-241

2.19e-38

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 137.19 E-value: 2.19e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   4 ANQETILELRDVKkyfpirsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQD 83
Cdd:PRK13648    2 EDKNSIIVFKNVS---------FQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 IS--NLSEeklrksVRKNIQMVFQDPfaslnPRKTLRSIIKE--PFNTHN-MYTMRERNEKVEELLARVGLHpSFAGRYP 158
Cdd:PRK13648   73 ITddNFEK------LRKHIGIVFQNP-----DNQFVGSIVKYdvAFGLENhAVPYDEMHRRVSEALKQVDML-ERADYEP 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 159 HEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRVGVMYLGK 238
Cdd:PRK13648  141 NALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGT 219


                  ...
gi 2181075557 239 MME 241
Cdd:PRK13648  220 VYK 222

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

35-248

3.53e-38

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 142.79 E-value: 3.53e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDP--FAsln 112
Cdd:PRK13657  350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVT----RASLRRNIAVVFQDAglFN--- 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 prktlRSI-----IKEPFNTH-NMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADE 186
Cdd:PRK13657  423 -----RSIednirVGRPDATDeEMRAAAERAQAHDFIERKPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDE 497

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 187 PVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMElTGKF-EL 248
Cdd:PRK13657  498 ATSALDVETEAKVKAALDELMK--GRTTFIIAHRLSTVRN-ADRILVFDNGRVVE-SGSFdEL 556

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

31-252

1.80e-37

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 133.98 E-value: 1.80e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ--DISNLSEEKLRKSVRKNIQMVFQDpf 108
Cdd:COG4161    13 GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPSEKAIRLLRQKVGMVFQQ-- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKT-LRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:COG4161    91 YNLWPHLTvMENLIEAPCKVLGL-SKEQAREKAMKLLARLRLTD-KADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEP 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMElTGKFELYDNP 252
Cdd:COG4161   169 TAALDPEITAQVVEIIRELSQT-GITQVIVTHEVEFARKVASQVVYMEKGRIIE-QGDASHFTQP 231

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

9-266

2.77e-37

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 136.89 E-value: 2.77e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirSGLFqrkvgdvkAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:PRK11607   19 LLEIRNLTKSF---DGQH--------AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 eeklrkSVRKNIQMVFQDpfASLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQR 168
Cdd:PRK11607   88 ------PYQRPINMMFQS--YALFPHMTVEQNIAFGLKQDKL-PKAEIASRVNEMLGLVHMQ-EFAKRKPHQLSGGQRQR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSI----QAQVINLMEELqeefNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTG 244
Cdd:PRK11607  158 VALARSLAKRPKLLLLDEPMGALDKKLrdrmQLEVVDILERV----GVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGE 233

                         250       260
                  ....*....|....*....|..
gi 2181075557 245 KFELYDNPLHPYTQALLSSVPV 266
Cdd:PRK11607  234 PEEIYEHPTTRYSAEFIGSVNV 255

HisP

COG4598

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

1-263

2.83e-37

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 133.77 E-value: 2.83e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAANQETiLELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK 80
Cdd:COG4598     1 MTDTAPPA-LEVRDLHKSF-----------GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVG 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDIsnlseeKLRKS---------------VRKNIQMVFQdpfaSLN--PRKT-LRSIIKEPFNTHNMyTMRERNEKVEE 142
Cdd:COG4598    69 GEEI------RLKPDrdgelvpadrrqlqrIRTRLGMVFQ----SFNlwSHMTvLENVIEAPVHVLGR-PKAEAIERAEA 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 143 LLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNlTYLFISHDLS 222
Cdd:COG4598   138 LLAKVGLA-DKRDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGR-TMLVVTHEMG 215

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2181075557 223 VVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSS 263
Cdd:COG4598   216 FARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERLRQFLSS 256

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

51-291

2.85e-37

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 135.70 E-value: 2.85e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  51 IVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrksvRKNIQMVFQDpfASLNPRKTLRSIIKEPFNthnm 130
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPH------LRHINMVFQS--YALFPHMTVEENVAFGLK---- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 131 ytMR-----ERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEE 205
Cdd:TIGR01187  69 --MRkvpraEIKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKT 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 206 LQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSVPVTRK-----------RGSVK 274
Cdd:TIGR01187 146 IQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEAtvierkseqvvLAGVE 225

                         250
                  ....*....|....*..
gi 2181075557 275 RERIVLKGELPSPANPP 291
Cdd:TIGR01187 226 GRRCDIYTDVPVEKDQP 242

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

11-249

5.29e-37

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 132.66 E-value: 5.29e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  11 ELRDVKKYFPIRSglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEE 90
Cdd:cd03249     2 EFKNVSFRYPSRP--------DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  91 KLRKsvrkNIQMVFQDP--FASlnprkTLRSIIKepfnthnmYTMRERNEKVEELLARVGLHPSFAGRYPHEF------- 161
Cdd:cd03249    74 WLRS----QIGLVSQEPvlFDG-----TIAENIR--------YGKPDATDEEVEEAAKKANIHDFIMSLPDGYdtlvger 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 ----SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLG 237
Cdd:cd03249   137 gsqlSGGQKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIRN-ADLIAVLQNG 213

                         250
                  ....*....|...
gi 2181075557 238 KMMElTGKF-ELY 249
Cdd:cd03249   214 QVVE-QGTHdELM 225

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

7-231

9.31e-37

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 131.79 E-value: 9.31e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPI--RSGLfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ-- 82
Cdd:COG4778     2 TTLLEVENLSKTFTLhlQGGK------RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDgg 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 --DISNLSE-EKLRksVRKN-IQMVFQdpFASLNPRKTLRSIIKEPfnthnmytMRERN-------EKVEELLARVGLHP 151
Cdd:COG4778    76 wvDLAQASPrEILA--LRRRtIGYVSQ--FLRVIPRVSALDVVAEP--------LLERGvdreearARARELLARLNLPE 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 152 SFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:COG4778   144 RLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRV 222

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

10-239

1.90e-36

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 130.61 E-value: 1.90e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03292     1 IEFINVTKTYP----------NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKsVRKNIQMVFQDpFASLNPRK-------TLRSIIKEPfnthnmytmRERNEKVEELLARVGL-HPSFAgrYPHEF 161
Cdd:cd03292    71 RAIPY-LRRKIGVVFQD-FRLLPDRNvyenvafALEVTGVPP---------REIRKRVPAALELVGLsHKHRA--LPAEL 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMeelqEEFNL---TYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03292   138 SGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLL----KKINKagtTVVVATHAKELVDTTRHRVIALERGK 213


                  .
gi 2181075557 239 M 239
Cdd:cd03292   214 L 214

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

34-248

2.96e-36

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 130.43 E-value: 2.96e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDpfaslnp 113
Cdd:cd03253    15 PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLD----SLRRAIGVVPQD------- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 rKTLrsiikepFNTHNMYTMR-----ERNEKVEELLARVGLHPSFAgRYPHEF-----------SGGQRQRIGIARALTL 177
Cdd:cd03253    84 -TVL-------FNDTIGYNIRygrpdATDEEVIEAAKAAQIHDKIM-RFPDGYdtivgerglklSGGEKQRVAIARAILK 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 178 NPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMELTGKFEL 248
Cdd:cd03253   155 NPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTHEEL 222

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

31-238

3.69e-36

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 129.58 E-value: 3.69e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlseEKLRKSV-----RKNIQMVFq 105
Cdd:cd03235    10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPL-----EKERKRIgyvpqRRSIDRDF- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dP-----FAS--LNPRKTLRSIIKepfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:cd03235    84 -PisvrdVVLmgLYGHKGLFRRLS-----------KADKAKVDEALERVGLS-ELADRQIGELSGGQQQRVLLARALVQD 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRvgVMYLGK 238
Cdd:cd03235   151 PDLLLLDEPFAGVDPKTQEDIYELLRELRRE-GMTILVVTHDLGLVLEYFDR--VLLLNR 207

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

35-234

6.73e-36

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 136.43 E-value: 6.73e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDPFAslnpr 114
Cdd:COG4987   350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDED----DLRRRIAVVPQRPHL----- 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 ktlrsiikepFNThnmyTMRErN----------EKVEELLARVGLHPsFAGRYPH-------E----FSGGQRQRIGIAR 173
Cdd:COG4987   421 ----------FDT----TLRE-NlrlarpdatdEELWAALERVGLGD-WLAALPDgldtwlgEggrrLSGGERRRLALAR 484

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 174 ALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHIsDRVGVM 234
Cdd:COG4987   485 ALLRDAPILLLDEPTEGLDAATEQALLADLLEALA--GRTVLLITHRLAGLERM-DRILVL 542

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

40-231

8.44e-36

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 129.10 E-value: 8.44e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQDISNLSEEKlrksvRKnIQMVFQDP--FASL- 111
Cdd:COG3840    19 DLTIAAGERVAILGPSGAGKSTllnliAG-----FLPPDSGRILWNGQDLTALPPAE-----RP-VSMLFQENnlFPHLt 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 ---------NPRktLRsiikepfnthnmYTMRERnEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELI 182
Cdd:COG3840    88 vaqniglglRPG--LK------------LTAEQR-AQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPIL 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2181075557 183 IADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRV 231
Cdd:COG3840   152 LLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRV 200

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

10-241

2.09e-35

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 127.72 E-value: 2.09e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03268     1 LKTNDLTKTY-----------GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklrksVRKNIQMVFQDPfaSLNPRKTLRsiikepfntHNMYT----MRERNEKVEELLARVGLHPSfAGRYPHEFSGGQ 165
Cdd:cd03268    70 ------ALRRIGALIEAP--GFYPNLTAR---------ENLRLlarlLGIRKKRIDEVLDVVGLKDS-AKKKVKGFSLGM 131

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 166 RQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:cd03268   132 KQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIE 206

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

26-239

2.34e-35

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 131.39 E-value: 2.34e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVkAVDgVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQI------LFKGQDISNLSEEKLRksvrkn 99
Cdd:TIGR02142   5 FSKRLGDF-SLD-ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIvlngrtLFDSRKGIFLPPEKRR------ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 100 IQMVFQDpfASLNPRKTLRSiikepfnthNM-YTMR-----ERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIAR 173
Cdd:TIGR02142  77 IGYVFQE--ARLFPHLSVRG---------NLrYGMKrarpsERRISFERVIELLGIGH-LLGRLPGRLSGGEKQRVAIGR 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 174 ALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:TIGR02142 145 ALLSSPRLLLMDEPLAALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRV 210

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

38-262

2.44e-35

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 128.71 E-value: 2.44e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfKGQDIS-----NLSEEK-LRKSVRKNIQMVFQDpFASL 111
Cdd:PRK11264   21 GIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI--RVGDITidtarSLSQQKgLIRQLRQHVGFVFQN-FNLF 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 NPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhpsfAGR---YPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:PRK11264   98 PHRTVLENIIEGPVIVKGE-PKEEATARARELLAKVGL----AGKetsYPRRLSGGQQQRVAIARALAMRPEVILFDEPT 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 189 SALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLS 262
Cdd:PRK11264  173 SALDPELVGEVLNTIRQLAQE-KRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQFLE 245

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

32-241

4.91e-35

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 127.35 E-value: 4.91e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklRKSVRKNIQMVFQDPFAsl 111
Cdd:cd03251    14 GPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYT----LASLRRQIGLVSQDVFL-- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 nprktlrsiikepFNThnmyTMRER---------NEKVEELLARVGLHpSFAGRYPHEF-----------SGGQRQRIGI 171
Cdd:cd03251    88 -------------FND----TVAENiaygrpgatREEVEEAARAANAH-EFIMELPEGYdtvigergvklSGGQRQRIAI 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 172 ARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMME 241
Cdd:cd03251   150 ARALLKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIEN-ADRIVVLEDGKIVE 216

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

10-239

5.64e-35

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 126.94 E-value: 5.64e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSe 89
Cdd:cd03245     3 IEFRNVSFSYPNQ---------EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLD- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklRKSVRKNIQMVFQDP--FASlnprkTLRSIIkepfnthnmyTMRERNEKVEELLA---RVGLHPsFAGRYPHEF--- 161
Cdd:cd03245    73 ---PADLRRNIGYVPQDVtlFYG-----TLRDNI----------TLGAPLADDERILRaaeLAGVTD-FVNKHPNGLdlq 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 --------SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVI-NLMEELQEEfnlTYLFISHDLSVVRhISDRVG 232
Cdd:cd03245   134 igergrglSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKeRLRQLLGDK---TLIIITHRPSLLD-LVDRII 209


                  ....*..
gi 2181075557 233 VMYLGKM 239
Cdd:cd03245   210 VMDSGRI 216

PRK13633

energy-coupling factor transporter ATPase;

35-245

6.89e-35

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 128.28 E-value: 6.89e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNlsEEKLRKsVRKNIQMVFQDPfaslnPR 114
Cdd:PRK13633   25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSD--EENLWD-IRNKAGMVFQNP-----DN 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KTLRSIIKE--PFNTHNM-YTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSAL 191
Cdd:PRK13633   97 QIVATIVEEdvAFGPENLgIPPEEIRERVDESLKKVGMY-EYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAML 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 192 DVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRVGVMYLGKM-MELTGK 245
Cdd:PRK13633  176 DPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVvMEGTPK 229

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

9-240

7.54e-35

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 127.89 E-value: 7.54e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlS 88
Cdd:PRK13639    1 ILETRDLKYSYP----------DGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK--Y 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHnmYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQR 168
Cdd:PRK13639   69 DKKSLLEVRKTVGIVFQNPDDQLFAPTVEEDVAFGPLNLG--LSKEEVEKRVKEALKAVGME-GFENKPPHHLSGGQKKR 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK13639  146 VAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKII 216

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

29-248

1.90e-34

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 125.95 E-value: 1.90e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTM--IRLYKPTEGQILFKGQDISNLS-EEKlrksVRKNIQMVFQ 105
Cdd:COG0396     9 SVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLmgHPKYEVTSGSILLDGEDILELSpDER----ARAGIFLAFQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DP--FASLNPRKTLRSIIKEpfNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHE-FSGGQRQRIGIARALTLNPELI 182
Cdd:COG0396    85 YPveIPGVSVSNFLRTALNA--RRGEELSAREFLKLLKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKLA 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 183 IADEPVSALDV-SIQAqVINLMEELQEEfNLTYLFISHDLSVVRHIS-DRVGVMYLGKMMElTGKFEL 248
Cdd:COG0396   163 ILDETDSGLDIdALRI-VAEGVNKLRSP-DRGILIITHYQRILDYIKpDFVHVLVDGRIVK-SGGKEL 227

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

34-237

1.98e-34

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 125.06 E-value: 1.98e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlseeklRKSVRKNIQMVFQDP---FAS 110
Cdd:cd03226    14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK-------AKERRKSIGYVMQDVdyqLFT 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLRSIIKEPfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSA 190
Cdd:cd03226    87 DSVREELLLGLKEL---------DAGNEQAETVLKDLDLY-ALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSG 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2181075557 191 LDVSIQAQVINLMEELQEEFNlTYLFISHDLSVVRHISDRvgVMYLG 237
Cdd:cd03226   157 LDYKNMERVGELIRELAAQGK-AVIVITHDYEFLAKVCDR--VLLLA 200

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

7-247

3.26e-34

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 131.08 E-value: 3.26e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKK-YFPIRSGLfqrkvgdVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK-GQDI 84
Cdd:TIGR03269 277 EPIIKVRNVSKrYISVDRGV-------VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEW 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEK--LRKSVRKNIQMVFQDpfASLNPRKTLRSIIKE------PFNTHNM---YTMRE---RNEKVEELLARvglh 150
Cdd:TIGR03269 350 VDMTKPGpdGRGRAKRYIGILHQE--YDLYPHRTVLDNLTEaiglelPDELARMkavITLKMvgfDEEKAEEILDK---- 423

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 151 psfagrYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDR 230
Cdd:TIGR03269 424 ------YPDELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDR 497

                         250
                  ....*....|....*..
gi 2181075557 231 VGVMYLGKMMElTGKFE 247
Cdd:TIGR03269 498 AALMRDGKIVK-IGDPE 513

PhnT

TIGR03258

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ...

36-252

6.65e-34

2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.

Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 127.80 E-value: 6.65e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP--TEGQILFKGQDISNLSEEKlrksvrKNIQMVFQDpfASLNP 113
Cdd:TIGR03258  21 LDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAagLTGRIAIADRDLTHAPPHK------RGLALLFQN--YALFP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:TIGR03258  93 HLKVEDNVAFGLRAQKM-PKADIAERVADALKLVGL-GDAAAHLPAQLSGGMQQRIAIARAIAIEPDVLLLDEPLSALDA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 194 SIQAQVINLMEELQEEF-NLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNP 252
Cdd:TIGR03258 171 NIRANMREEIAALHEELpELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAP 230

cbiO

PRK13637

energy-coupling factor transporter ATPase;

34-245

7.25e-34

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 125.93 E-value: 7.25e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlsEEKLR-KSVRKNIQMVFQDPFASLN 112
Cdd:PRK13637   21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDIT---DKKVKlSDIRKKVGLVFQYPEYQLF 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 PRKTLRSIIKEPFNTHnmYTMRERNEKVEELLARVGL-HPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSAL 191
Cdd:PRK13637   98 EETIEKDIAFGPINLG--LSEEEIENRVKRAMNIVGLdYEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGL 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 192 DVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKmMELTGK 245
Cdd:PRK13637  176 DPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGK-CELQGT 228

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

39-234

1.25e-33

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 126.75 E-value: 1.25e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQDisnLSEEKLRKSV---RKNIQMVFQDP--F 108
Cdd:COG4148    18 VDFTLPGRGVTALFGPSGSGKTTllraiAG-----LERPDSGRIRLGGEV---LQDSARGIFLpphRRRIGYVFQEArlF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKTLRsiikepfnthnmYTMR-----ERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:COG4148    90 PHLSVRGNLL------------YGRKrapraERRISFDEVVELLGIGH-LLDRRPATLSGGERQRVAIGRALLSSPRLLL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:COG4148   157 MDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLL 207

cbiO

PRK13650

energy-coupling factor transporter ATPase;

36-249

2.98e-33

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 124.07 E-value: 2.98e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDisnLSEEKLRKsVRKNIQMVFQdpfaslNPRK 115
Cdd:PRK13650   23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDL---LTEENVWD-IRHKIGMVFQ------NPDN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIKE---PFNTHN----MYTMRERnekVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:PRK13650   93 QFVGATVEddvAFGLENkgipHEEMKER---VNEALELVGMQ-DFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEAT 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 189 SALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRhISDRVGVMYLGKMMELTGKFELY 249
Cdd:PRK13650  169 SMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRELF 228

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

35-260

3.69e-33

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 122.59 E-value: 3.69e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQ--MVF----QDPF 108
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQenVLFnrsiRDNI 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGlhpsfAGrypheFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:cd03252    97 ALADPGMSMERVIEAAKLAGAHDFISELPEGYDTIVGEQG-----AG-----LSGGQRQRIAIARALIHNPRILIFDEAT 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 189 SALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMELTGKFELYD-NPLHPYTQAL 260
Cdd:cd03252   167 SALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAeNGLYAYLYQL 236

CP_lyasePhnL

TIGR02324

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ...

9-231

6.58e-33

phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.

Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 121.34 E-value: 6.58e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsgLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ----DI 84
Cdd:TIGR02324   1 LLEVEDLSKTFT----LHQQGGVRLPVLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYANYLPDSGRILVRHEgawvDL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLRKSVRKNIQMVFQdpFASLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPSFAGRYPHEFSGG 164
Cdd:TIGR02324  77 AQASPREVLEVRRKTIGYVSQ--FLRVIPRVSALEVVAEPLLERGV-PREAARARARELLARLNIPERLWHLPPATFSGG 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:TIGR02324 154 EQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKAR-GAALIGIFHDEEVRELVADRV 219

oligo_HPY

TIGR01727

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ...

238-327

7.32e-33

oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 117.08 E-value: 7.32e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 238 KMMELTGKFELYDNPLHPYTQALLSSVPVTRKRGsvkRERIVLKGELPSPANPPKGCVFHTRCPVAKPICKEQIPEFKEA 317
Cdd:TIGR01727   1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIKKRD---RKLISIPGEVPSLINLPSGCRFYPRCPYAQDECRKEPPALVEI 77

                          90
                  ....*....|
gi 2181075557 318 APSHFVACHL 327
Cdd:TIGR01727  78 AEGHRVACHL 87

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

36-242

1.83e-32

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 120.65 E-value: 1.83e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvrkniqMVFQDpfASLNPRK 115
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRM---------VVFQN--YSLLPWL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIKEPFNTHNMYTMR-ERNEKVEELLARVGLHPSfAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVS 194
Cdd:TIGR01184  70 TVRENIALAVDRVLPDLSKsERRAIVEEHIALVGLTEA-ADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDAL 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 195 IQAqviNLMEELQ---EEFNLTYLFISHDLSVVRHISDRVGVM------YLGKMMEL 242
Cdd:TIGR01184 149 TRG---NLQEELMqiwEEHRVTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILEV 202

cbiO

PRK13646

energy-coupling factor transporter ATPase;

34-249

2.32e-32

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 121.81 E-value: 2.32e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFASLNP 113
Cdd:PRK13646   21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNtHNMyTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:PRK13646  101 DTVEREIIFGPKN-FKM-NLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDP 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 194 SIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELY 249
Cdd:PRK13646  179 QSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

35-239

4.83e-32

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 120.48 E-value: 4.83e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIS--NLSEeklrksVRKNIQMVFQDP---FA 109
Cdd:PRK13632   24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISkeNLKE------IRKKIGIIFQNPdnqFI 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SLnprkTLRSIIKepFNTHN-MYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:PRK13632   98 GA----TVEDDIA--FGLENkKVPPKKMKDIIDDLAKKVGME-DYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDEST 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 189 SALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRhISDRVGVMYLGKM 239
Cdd:PRK13632  171 SMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKL 220

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

6-240

4.96e-32

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 120.72 E-value: 4.96e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIs 85
Cdd:PRK13636    2 EDYILKVEELNYNYS----------DGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  86 NLSEEKLRKsVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHnmYTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQ 165
Cdd:PRK13636   71 DYSRKGLMK-LRESVGMVFQDPDNQLFSASVYQDVSFGAVNLK--LPEDEVRKRVDNALKRTGIEH-LKDKPTHCLSFGQ 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 166 RQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK13636  147 KKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

39-244

5.19e-32

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 119.54 E-value: 5.19e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKlrKSVRKNIQMVFQDPFASLNPRKTLR 118
Cdd:PRK11629   28 VSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAA--KAELRNQKLGFIYQFHHLLPDFTAL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 119 SIIKEPFNTHNMYTmRERNEKVEELLARVGLHPSFAGRyPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQ 198
Cdd:PRK11629  106 ENVAMPLLIGKKKP-AEINSRALEMLAAVGLEHRANHR-PSELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADS 183

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2181075557 199 VINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM--YLGKMMELTG 244
Cdd:PRK11629  184 IFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRdgRLTAELSLMG 231

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

5-239

7.13e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 124.37 E-value: 7.13e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILF 79
Cdd:COG3845     1 MMPPALELRGITKRF-----------GGVVANDDVSLTVRPGEIHALLGENGAGKSTlmkilYG-----LYQPDSGEILI 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQ--DISNlseekLRKSVRKNIQMVFQ-----DPF-------ASLNPRKTLRsiikepfnthnmYTMRERNEKVEELLA 145
Cdd:COG3845    65 DGKpvRIRS-----PRDAIALGIGMVHQhfmlvPNLtvaenivLGLEPTKGGR------------LDRKAARARIRELSE 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 146 RVGLH--PSfagRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALdvSIQ--AQVINLMEELQEEfNLTYLFISHDL 221
Cdd:COG3845   128 RYGLDvdPD---AKVEDLSVGEQQRVEILKALYRGARILILDEPTAVL--TPQeaDELFEILRRLAAE-GKSIIFITHKL 201

                         250
                  ....*....|....*...
gi 2181075557 222 SVVRHISDRVGVMYLGKM 239
Cdd:COG3845   202 REVMAIADRVTVLRRGKV 219

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

31-205

7.33e-32

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 117.97 E-value: 7.33e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlseEKLRKSVRKNIQMVFQDP--F 108
Cdd:COG4133    13 GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPI-----RDAREDYRRRLAYLGHADglK 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKTLRSIIKepfnthnMYTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:COG4133    88 PELTVRENLRFWAA-------LYGLRADREAIDEALEAVGLAG-LADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPF 159

                         170
                  ....*....|....*..
gi 2181075557 189 SALDVSIQAQVINLMEE 205
Cdd:COG4133   160 TALDAAGVALLAELIAA 176

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

10-238

7.66e-32

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 118.69 E-value: 7.66e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:cd03224     1 LEVENLNAGY-----------GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLrksVRKNIQMVFQDP--FASLNPRKTLRsiikepfnthnMYTMRERNEKVEELLARV-GLHP---SFAGRYPHEFSG 163
Cdd:cd03224    70 HER---ARAGIGYVPEGRriFPELTVEENLL-----------LGAYARRRAKRKARLERVyELFPrlkERRKQLAGTLSG 135

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03224   136 GEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGR 209

cbiO

PRK13642

energy-coupling factor transporter ATPase;

29-249

2.94e-31

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 118.66 E-value: 2.94e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdisNLSEEKLRkSVRKNIQMVFQDPf 108
Cdd:PRK13642   16 KESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGE---LLTAENVW-NLRRKIGMVFQNP- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 aslnPRKTLRSIIKE--PFNTHNMYTMRERN-EKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIAD 185
Cdd:PRK13642   91 ----DNQFVGATVEDdvAFGMENQGIPREEMiKRVDEALLAVNML-DFKTREPARLSGGQKQRVAVAGIIALRPEIIILD 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 186 EPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRVGVMYLGKMMELTGKFELY 249
Cdd:PRK13642  166 ESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

10-258

7.07e-31

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 116.94 E-value: 7.07e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRT---MIRLYKP--TEGQILFKGQDI 84
Cdd:PRK14247    4 IEIRDLKVSF-----------GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVfnrLIELYPEarVSGEVYLDGQDI 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLRKSVrkniQMVFQDPfaslNPRKTLrSIIKE----PFNTHNMYTMRERNEKVEELLARVGLHPSFAGRY--- 157
Cdd:PRK14247   73 FKMDVIELRRRV----QMVFQIP----NPIPNL-SIFENvalgLKLNRLVKSKKELQERVRWALEKAQLWDEVKDRLdap 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 158 PHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfnLTYLFISHDLSVVRHISDRVGVMYLG 237
Cdd:PRK14247  144 AGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKG 221

                         250       260
                  ....*....|....*....|.
gi 2181075557 238 KMMELTGKFELYDNPLHPYTQ 258
Cdd:PRK14247  222 QIVEWGPTREVFTNPRHELTE 242

type_I_sec_LssB

TIGR03375

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...

32-240

7.72e-31

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]

Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 122.67 E-value: 7.72e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKsvrkNIQMVFQDP--FA 109
Cdd:TIGR03375 477 ETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRR----NIGYVPQDPrlFY 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SlnprkTLRSIIkepfnthnmyTMRERNEKVEELLA---RVGLHpSFAGRYPHEF-----------SGGQRQRIGIARAL 175
Cdd:TIGR03375 553 G-----TLRDNI----------ALGAPYADDEEILRaaeLAGVT-EFVRRHPDGLdmqigergrslSGGQRQAVALARAL 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 176 TLNPELIIADEPVSALDVSIQAQVI-NLMEELQEEfnlTYLFISHDLSVVRhISDRVGVMYLGKMM 240
Cdd:TIGR03375 617 LRDPPILLLDEPTSAMDNRSEERFKdRLKRWLAGK---TLVLVTHRTSLLD-LVDRIIVMDNGRIV 678

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

10-239

8.56e-31

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 119.03 E-value: 8.56e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:PRK10851    3 IEIANIKKSF-----------GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKlrksvrKNIQMVFQ-----------DPFA---SLNPRKtlrsiiKEPfnthNMYTMRernEKVEELLARVGLhPSFAG 155
Cdd:PRK10851   72 RD------RKVGFVFQhyalfrhmtvfDNIAfglTVLPRR------ERP----NAAAIK---AKVTQLLEMVQL-AHLAD 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 156 RYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:PRK10851  132 RYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMS 211


                  ....
gi 2181075557 236 LGKM 239
Cdd:PRK10851  212 QGNI 215

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

35-252

1.29e-30

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 115.28 E-value: 1.29e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQDP--FASln 112
Cdd:cd03244    19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSR----ISIIPQDPvlFSG-- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 prkTLRSIIkEPFNTHNmytmrerNEKVEELLARVGL---HPSFAGRYPHE-------FSGGQRQRIGIARALTLNPELI 182
Cdd:cd03244    93 ---TIRSNL-DPFGEYS-------DEELWQALERVGLkefVESLPGGLDTVveeggenLSVGQRQLLCLARALLRKSKIL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 183 IADEPVSALDVSIQAQVinlMEELQEEF-NLTYLFISHDLSVVRHiSDRVGVMYLGKMMEltgkfelYDNP 252
Cdd:cd03244   162 VLDEATASVDPETDALI---QKTIREAFkDCTVLTIAHRLDTIID-SDRILVLDKGRVVE-------FDSP 221

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

10-220

1.50e-30

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 116.11 E-value: 1.50e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsGLFQRKVgdvkAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQDI 84
Cdd:COG4525     4 LTVRHVSVRYP---GGGQPQP----ALQDVSLTIESGEFVVALGASGCGKTTllnliAG-----FLAPSSGEITLDGVPV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKlrkSVrkniqmVFQD----PFasLNPRK------TLRSIIKepfnthnmytmRERNEKVEELLARVGLHpSFA 154
Cdd:COG4525    72 TGPGADR---GV------VFQKdallPW--LNVLDnvafglRLRGVPK-----------AERRARAEELLALVGLA-DFA 128

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 155 GRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHD 220
Cdd:COG4525   129 RRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHS 194

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

10-239

2.05e-30

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 114.30 E-value: 2.05e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKG-------- 81
Cdd:cd03269     1 LEVENVTKRF-----------GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGkpldiaar 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEK-LRKSVRKNIQMVFqdpFASLnprktlrsiikepfntHNMyTMRERNEKVEELLARVGLHPsFAGRYPHE 160
Cdd:cd03269    70 NRIGYLPEERgLYPKMKVIDQLVY---LAQL----------------KGL-KKEEARRRIDEWLERLELSE-YANKRVEE 128

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03269   129 LSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRA 206

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

10-240

6.61e-30

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 113.37 E-value: 6.61e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrT--MIR-LYKPTEGQILFKGQDISn 86
Cdd:cd03263     1 LQIRNLTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTT---TlkMLTgELRPTSGTAYINGYSIR- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 lseeKLRKSVRKNIQMVFQDP--FASLNPRKTLR--SIIKEPFNthnmytmRERNEKVEELLARVGLHPsFAGRYPHEFS 162
Cdd:cd03263    68 ----TDRKAARQSLGYCPQFDalFDELTVREHLRfyARLKGLPK-------SEIKEEVELLLRVLGLTD-KANKRARTLS 135

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:cd03263   136 GGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRK--GRSIILTTHSMDEAEALCDRIAIMSDGKLR 211

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

10-241

7.01e-30

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 119.44 E-value: 7.01e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:TIGR02203 331 VEFRNVTFRYPGR---------DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTL 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQ--MVFQDPFASlNPRKTLRSIIKEpfnthnmytmrernEKVEELLARVGLHpSFAGRYPHEF------ 161
Cdd:TIGR02203 402 ASLRRQVALVSQdvVLFNDTIAN-NIAYGRTEQADR--------------AEIERALAAAYAQ-DFVDKLPLGLdtpige 465

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 -----SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYL 236
Cdd:TIGR02203 466 ngvllSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQ--GRTTLVIAHRLSTIEK-ADRIVVMDD 542


                  ....*
gi 2181075557 237 GKMME 241
Cdd:TIGR02203 543 GRIVE 547

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

36-220

7.49e-30

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 112.96 E-value: 7.49e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKST-----AGrTMIRLYKpTEGQILFKGQDISNLSEEklrksvRKNIQMVFQDP--F 108
Cdd:COG4136    17 LAPLSLTVAPGEILTLMGPSGSGKSTllaaiAG-TLSPAFS-ASGEVLLNGRRLTALPAE------QRRIGILFQDDllF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKTLrsiikePFNTHNMYTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:COG4136    89 PHLSVGENL------AFALPPTIGRAQRRARVEQALEEAGL-AGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPF 161

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2181075557 189 SALDVSIQAQVINLMEELQEEFNLTYLFISHD 220
Cdd:COG4136   162 SKLDAALRAQFREFVFEQIRQRGIPALLVTHD 193

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

9-221

9.67e-30

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 114.03 E-value: 9.67e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRtmirlYKPTEGQILFKGQD 83
Cdd:COG1101     1 MLELKNLSKTF------NPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTllnaiAGS-----LPPDSGSILIDGKD 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSEEKlrksvR-KNIQMVFQDPFASLNPRKTlrsiIKEpfnthNM--------------YTMRERNEKVEELLA--- 145
Cdd:COG1101    70 VTKLPEYK-----RaKYIGRVFQDPMMGTAPSMT----IEE-----NLalayrrgkrrglrrGLTKKRRELFRELLAtlg 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 146 ---------RVGLhpsfagrypheFSGGQRQrigiarALTL------NPELIIADEPVSALDVSIQAQVINLMEELQEEF 210
Cdd:COG1101   136 lglenrldtKVGL-----------LSGGQRQ------ALSLlmatltKPKLLLLDEHTAALDPKTAALVLELTEKIVEEN 198

                         250
                  ....*....|.
gi 2181075557 211 NLTYLFISHDL 221
Cdd:COG1101   199 NLTTLMVTHNM 209

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

9-239

1.06e-29

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 114.82 E-value: 1.06e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN-- 86
Cdd:COG4152     1 MLELKGLTKRF-----------GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPed 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 ------LSEEK-LRKSVRKNIQMVFqdpFASLnprktlrsiikepfntHNMyTMRERNEKVEELLARVGLhPSFAGRYPH 159
Cdd:COG4152    70 rrrigyLPEERgLYPKMKVGEQLVY---LARL----------------KGL-SKAEAKRRADEWLERLGL-GDRANKKVE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDvSIQAQVI-NLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:COG4152   129 ELSKGNQQKVQLIAALLHDPELLILDEPFSGLD-PVNVELLkDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGR 206


                  .
gi 2181075557 239 M 239
Cdd:COG4152   207 K 207

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

5-252

1.95e-29

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 118.67 E-value: 1.95e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKKYFPIRSglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI 84
Cdd:TIGR00958 474 NLEGLIEFQDVSFSYPNRP--------DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPL 545

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLRKSVRkniqMVFQDP--FAslnprktlRSIikepfnTHNMYTMRERNEKVEELLARV--GLHpSFAGRYPHE 160
Cdd:TIGR00958 546 VQYDHHYLHRQVA----LVGQEPvlFS--------GSV------RENIAYGLTDTPDEEIMAAAKaaNAH-DFIMEFPNG 606

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 161 F-----------SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAqvinLMEELQEEFNLTYLFISHDLSVVRHiSD 229
Cdd:TIGR00958 607 YdtevgekgsqlSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQ----LLQESRSRASRTVLLIAHRLSTVER-AD 681

                         250       260
                  ....*....|....*....|...
gi 2181075557 230 RVGVMYLGKMMELTGKFELYDNP 252
Cdd:TIGR00958 682 QILVLKKGSVVEMGTHKQLMEDQ 704

cbiO

PRK13641

energy-coupling factor transporter ATPase;

34-252

2.06e-29

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 113.77 E-value: 2.06e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFASLNP 113
Cdd:PRK13641   21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKKLRKKVSLVFQFPEAQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNTHnmYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:PRK13641  101 NTVLKDVEFGPKNFG--FSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDP 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 194 SIQAQVINLMEELQEEFNlTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNP 252
Cdd:PRK13641  179 EGRKEMMQLFKDYQKAGH-TVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

23-238

3.20e-29

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 112.39 E-value: 3.20e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  23 SGLFQRkVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKL-RKSVRKNIQ 101
Cdd:PRK11300    9 SGLMMR-FGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIaRMGVVRTFQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 102 MV--FQDPFASLN-----PRKTLRSIIKEPFNTHNmYTMRERN--EKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIA 172
Cdd:PRK11300   88 HVrlFREMTVIENllvaqHQQLKTGLFSGLLKTPA-FRRAESEalDRAATWLERVGLLE-HANRQAGNLAYGQQRRLEIA 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 173 RALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:PRK11300  166 RCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGT 231

NHLM_micro_ABC2

TIGR03797

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ...

37-247

4.09e-29

NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 117.75 E-value: 4.09e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  37 DGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDpfASLNPRKT 116
Cdd:TIGR03797 470 DDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGLDVQ----AVRRQLGVVLQN--GRLMSGSI 543

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 117 LRSIIkepfnTHNMYTMRERNEKVEEL-LAR------VGLHP--SFAGRyphEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:TIGR03797 544 FENIA-----GGAPLTLDEAWEAARMAgLAEdirampMGMHTviSEGGG---TLSGGQRQRLLIARALVRKPRILLFDEA 615

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 188 VSALDVSIQAQVINLMEELqeefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMElTGKFE 247
Cdd:TIGR03797 616 TSALDNRTQAIVSESLERL----KVTRIVIAHRLSTIRN-ADRIYVLDAGRVVQ-QGTYD 669

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

30-258

4.59e-29

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 112.45 E-value: 4.59e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  30 VGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK------PTEGQILFKGQDISNLSEEKLRKSVrkniQMV 103
Cdd:PRK14246   20 INDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIFQIDAIKLRKEV----GMV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 104 FQDPfaSLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRY---PHEFSGGQRQRIGIARALTLNPE 180
Cdd:PRK14246   96 FQQP--NPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLnspASQLSGGQQQRLTIARALALKPK 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 181 LIIADEPVSALDVSIQAQVINLMEELQEEfnLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQ 258
Cdd:PRK14246  174 VLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTE 249

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

31-264

4.89e-29

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 111.86 E-value: 4.89e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK-----PTEGQILFKGQDISNLSEEKLRksVRKNIQMVFQ 105
Cdd:PRK14267   15 GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLElneeaRVEGEVRLFGRNIYSPDVDPIE--VRREVGMVFQ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 --DPFaslnPRKTLRSIIKEPFNTHNMYTMR-ERNEKVEELLARVGLHPSFAGR---YPHEFSGGQRQRIGIARALTLNP 179
Cdd:PRK14267   93 ypNPF----PHLTIYDNVAIGVKLNGLVKSKkELDERVEWALKKAALWDEVKDRlndYPSNLSGGQRQRLVIARALAMKP 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEFnlTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQA 259
Cdd:PRK14267  169 KILLMDEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEK 246


                  ....*
gi 2181075557 260 LLSSV 264
Cdd:PRK14267  247 YVTGA 251

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

26-238

5.05e-29

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 112.81 E-value: 5.05e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKvgdvkAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQ 105
Cdd:PRK13634   18 FERR-----ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKKLKPLRKKVGIVFQ 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPFASLNPRKTLRSIIKEPFNthnmYTMRERN--EKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:PRK13634   93 FPEHQLFEETVEKDICFGPMN----FGVSEEDakQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLV 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:PRK13634  169 LDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGT 223

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

26-238

6.84e-29

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 110.54 E-value: 6.84e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrksVRKNIQMVFq 105
Cdd:cd03266    11 FRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAE-----ARRRLGFVS- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPFAsLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIAD 185
Cdd:cd03266    85 DSTG-LYDRLTARENLEYFAGLYGL-KGDELTARLEELADRLGMEE-LLDRRVGGFSTGMRQKVAIARALVHDPPVLLLD 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 186 EPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03266   162 EPTTGLDVMATRALREFIRQLRAL-GKCILFSTHIMQEVERLCDRVVVLHRGR 213

MsbA_rel

TIGR02204

ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ...

32-249

6.87e-29

ABC transporter, permease/ATP-binding protein; This protein is related to a Proteobacterial ATP transporter that exports lipid A and to eukaryotic P-glycoproteins.

Pssm-ID: 131259 [Multi-domain] Cd Length: 576 Bit Score: 116.72 E-value: 6.87e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQDPfasl 111
Cdd:TIGR02204 352 DQPALDGLNLTVRPGETVALVGPSGAGKSTLFQLLLRFYDPQSGRILLDGVDLRQLDPAELRAR----MALVPQDP---- 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 nprkTLrsiikepFNTHNMYTMRERN-----EKVEELlARVGLHPSFAGRYPHEF-----------SGGQRQRIGIARAL 175
Cdd:TIGR02204 424 ----VL-------FAASVMENIRYGRpdatdEEVEAA-ARAAHAHEFISALPEGYdtylgergvtlSGGQRQRIAIARAI 491

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 176 TLNPELIIADEPVSALDVSIQAQVINLMEELQEEfnLTYLFISHDLSVVRHiSDRVGVMYLGKMM------ELTGKFELY 249
Cdd:TIGR02204 492 LKDAPILLLDEATSALDAESEQLVQQALETLMKG--RTTLIIAHRLATVLK-ADRIVVMDQGRIVaqgthaELIAKGGLY 568

cbiO

PRK13645

energy-coupling factor transporter ATPase;

32-266

7.32e-29

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 112.41 E-value: 7.32e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTagrtMIRLykpTEGQILFK-GQDI-------SNLSEEKLRKSVRKNIQMV 103
Cdd:PRK13645   23 EFKALNNTSLTFKKNKVTCVIGTTGSGKST----MIQL---TNGLIISEtGQTIvgdyaipANLKKIKEVKRLRKEIGLV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 104 FQDPFASLNPRKTLRSIIKEPFNTHNmyTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:PRK13645   96 FQFPEYQLFQETIEKDIAFGPVNLGE--NKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLV 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNplhpytQALLSS 263
Cdd:PRK13645  174 LDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN------QELLTK 247


                  ...
gi 2181075557 264 VPV 266
Cdd:PRK13645  248 IEI 250

type_I_sec_HlyB

TIGR01846

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ...

36-248

1.65e-28

type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 116.00 E-value: 1.65e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKsvrkNIQMVFQDPFasLNPRK 115
Cdd:TIGR01846 473 LSNLNLDIKPGEFIGIVGPSGSGKSTLTKLLQRLYTPQHGQVLVDGVDLAIADPAWLRR----QMGVVLQENV--LFSRS 546

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSI-IKEPfnthNMytmreRNEKVEELLARVGLHpSFAGRYPHEF-----------SGGQRQRIGIARALTLNPELII 183
Cdd:TIGR01846 547 IRDNIaLCNP----GA-----PFEHVIHAAKLAGAH-DFISELPQGYntevgekganlSGGQRQRIAIARALVGNPRILI 616

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMMELTGKFEL 248
Cdd:TIGR01846 617 FDEATSALDYESEALIMRNMREICR--GRTVIIIAHRLSTVRA-CDRIIVLEKGQIAESGRHEEL 678

PRK14239

phosphate transporter ATP-binding protein; Provisional

7-262

2.74e-28

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 109.87 E-value: 2.74e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRL--YKP---TEGQILFKG 81
Cdd:PRK14239    3 EPILQVSDLSVYY-----------NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndLNPevtITGSIVYNG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLRksVRKNIQMVFQDPfaslNPRktlrsiikePFNTHN--MYTMRERNEKVEELLARV------------ 147
Cdd:PRK14239   72 HNIYSPRTDTVD--LRKEIGMVFQQP----NPF---------PMSIYEnvVYGLRLKGIKDKQVLDEAvekslkgasiwd 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 148 ----GLHPSFAGrypheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFnlTYLFISHDLSV 223
Cdd:PRK14239  137 evkdRLHDSALG-----LSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQ 209

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2181075557 224 VRHISDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLS 262
Cdd:PRK14239  210 ASRISDRTGFFLDGDLIEYNDTKQMFMNPKHKETEDYIS 248

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

36-239

4.76e-28

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 106.92 E-value: 4.76e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvRKNIQMVFQDP--FASlnp 113
Cdd:cd03246    18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL----GDHVGYLPQDDelFSG--- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 rkTLRSIIkepfnthnmytmrernekveellarvglhpsfagrypheFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:cd03246    91 --SIAENI---------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDV 129

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2181075557 194 SIQAQVINLMEELQEEfNLTYLFISHDLSVVRhISDRVGVMYLGKM 239
Cdd:cd03246   130 EGERALNQAIAALKAA-GATRIVIAHRPETLA-SADRILVLEDGRV 173

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

7-239

5.88e-28

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 108.33 E-value: 5.88e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:cd03248     9 KGIVKFQNVTFAYPTRP--------DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLRKSVrkniQMVFQDP--FAslnprKTLRSIIKEPFNTHNMytmrernEKVEELLARVGLHpSFAGRYPHEF--- 161
Cdd:cd03248    81 YEHKYLHSKV----SLVGQEPvlFA-----RSLQDNIAYGLQSCSF-------ECVKEAAQKAHAH-SFISELASGYdte 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 --------SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGV 233
Cdd:cd03248   144 vgekgsqlSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPE--RRTVLVIAHRLSTVER-ADQILV 220


                  ....*.
gi 2181075557 234 MYLGKM 239
Cdd:cd03248   221 LDGGRI 226

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

29-250

8.11e-28

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 107.23 E-value: 8.11e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRL--YKPTEGQILFKGQDISNLS-EEKlrksVRKNIQMVFQ 105
Cdd:cd03217     9 SVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDLPpEER----ARLGIFLAFQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DP--FASLNPRKTLRSIikepfnthnmytmrerNEKveellarvglhpsfagrypheFSGGQRQRIGIARALTLNPELII 183
Cdd:cd03217    85 YPpeIPGVKNADFLRYV----------------NEG---------------------FSGGEKKRNEILQLLLLEPDLAI 127

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHI-SDRVGVMYLGKMMElTGKFELYD 250
Cdd:cd03217   128 LDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHYQRLLDYIkPDRVHVLYDGRIVK-SGDKELAL 193

PRK10908

cell division ATP-binding protein FtsE;

30-239

1.60e-27

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 107.27 E-value: 1.60e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  30 VGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrKSVRKNIQMVFQDPFA 109
Cdd:PRK10908   12 LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREV-PFLRRQIGMIFQDHHL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SLNprKTLRSIIKEPFNTHNMYTMRERnEKVEELLARVGLHPSfAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PRK10908   91 LMD--RTVYDNVAIPLIIAGASGDDIR-RRVSAALDKVGLLDK-AKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTG 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2181075557 190 ALDVSIQAQVINLMEELQeEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:PRK10908  167 NLDDALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

34-238

2.60e-27

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 106.12 E-value: 2.60e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGeTLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlseeKLRKSVRKNIQMVFQDP------ 107
Cdd:cd03264    14 RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVL-----KQPQKLRRRIGYLPQEFgvypnf 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 --FASLNPRKTLRSIIKepfnthnmytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIAD 185
Cdd:cd03264    88 tvREFLDYIAWLKGIPS-----------KEVKARVDEVLELVNLGD-RAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 186 EPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03264   156 EPTAGLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGK 206

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

31-240

3.92e-27

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 107.02 E-value: 3.92e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVrkniqmvfqdpfaS 110
Cdd:PRK11231   13 GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRL-------------A 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRK-------TLRSII---KEPFNTHNMYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPE 180
Cdd:PRK11231   80 LLPQHhltpegiTVRELVaygRSPWLSLWGRLSAEDNARVNQAMEQTRIN-HLADRRLTDLSGGQRQRAFLAMVLAQDTP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 181 LIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK11231  159 VVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVM 217

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

34-234

4.12e-27

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 111.22 E-value: 4.12e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEeklrKSVRKNIQMVFQDPFAslnP 113
Cdd:TIGR02857 336 PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADA----DSWRDQIAWVPQHPFL---F 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKepfnthnMYTMRERNEKVEELLARVGLHPSFA----------GRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:TIGR02857 409 AGTIAENIR-------LARPDASDAEIREALERAGLDEFVAalpqgldtpiGEGGAGLSGGQAQRLALARAFLRDAPLLL 481

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVrHISDRVGVM 234
Cdd:TIGR02857 482 LDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALA-ALADRIVVL 529

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

5-241

5.83e-27

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 105.57 E-value: 5.83e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKkyfpirsglFQrkVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI 84
Cdd:PRK10247    3 ENSPLLQLQNVG---------YL--AGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDI 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLRKSVRKNIQ--MVFQDpfaslnprkTLRSIIKEPFNThnmytmreRNEKVEEL-----LARVGLHPSFAGRY 157
Cdd:PRK10247   72 STLKPEIYRQQVSYCAQtpTLFGD---------TVYDNLIFPWQI--------RNQQPDPAiflddLERFALPDTILTKN 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 158 PHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM-YL 236
Cdd:PRK10247  135 IAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINHADKVITLQpHA 214


                  ....*
gi 2181075557 237 GKMME 241
Cdd:PRK10247  215 GEMQE 219

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

45-239

1.07e-26

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 104.50 E-value: 1.07e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  45 KGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLseeklrKSVRKNIQMVFQDP--FASL----------N 112
Cdd:cd03298    23 QGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAA------PPADRPVSMLFQENnlFAHLtveqnvglglS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 PRKTLRSiikepfnthnmytmrERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:cd03298    97 PGLKLTA---------------EDRQAIEVALARVGLA-GLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALD 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2181075557 193 VSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03298   161 PALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207

cbiO

PRK13649

energy-coupling factor transporter ATPase;

34-245

1.29e-26

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 106.37 E-value: 1.29e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFASLNP 113
Cdd:PRK13649   21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIRKKVGLVFQFPESQLFE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIikePFNTHNMYTMRERNEKV-EELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:PRK13649  101 ETVLKDV---AFGPQNFGVSQEEAEALaREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLD 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 193 VSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMeLTGK 245
Cdd:PRK13649  178 PKGRKELMTLFKKLHQS-GMTIVLVTHLMDDVANYADFVYVLEKGKLV-LSGK 228

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

5-291

1.35e-26

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 105.53 E-value: 1.35e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILfKGQdi 84
Cdd:PRK11247    8 NQGTPLLLNAVSKRY-----------GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELL-AGT-- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEeklrksVRKNIQMVFQDpfASLNPRKT--------LRSIIKepfnthnmytmrernEKVEELLARVGLHPSfAGR 156
Cdd:PRK11247   74 APLAE------AREDTRLMFQD--ARLLPWKKvidnvglgLKGQWR---------------DAALQALAAVGLADR-ANE 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 157 YPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYL 236
Cdd:PRK11247  130 WPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEE 209

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 237 GKM-MELTgkfelydnplhpytqallSSVPVTRKRGSVK---RERIVLKGELPSPANPP 291
Cdd:PRK11247  210 GKIgLDLT------------------VDLPRPRRRGSARlaeLEAEVLQRVMSRGESEP 250

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

37-234

1.46e-26

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 109.91 E-value: 1.46e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  37 DGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDPfaSLnprkt 116
Cdd:COG5265   375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQA----SLRAAIGIVPQDT--VL----- 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 117 lrsiikepFNThnmyTMRErN----------EKVEELLARVGLHPsFAGRYPHEF-----------SGGQRQRIGIARAL 175
Cdd:COG5265   444 --------FND----TIAY-NiaygrpdaseEEVEAAARAAQIHD-FIESLPDGYdtrvgerglklSGGEKQRVAIARTL 509

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 176 TLNPELIIADEPVSALDV----SIQAQvinlMEELQEefNLTYLFISHDLSVVRHiSDRVGVM 234
Cdd:COG5265   510 LKNPPILIFDEATSALDSrterAIQAA----LREVAR--GRTTLVIAHRLSTIVD-ADEILVL 565

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

10-252

1.50e-26

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 107.62 E-value: 1.50e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRtMIR-LYKPTEGQILFKGQDISNLs 88
Cdd:PRK11650    4 LKLQAVRKSYD----------GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLR-MVAgLERITSGEIWIGGRVVNEL- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRksvrkNIQMVFQDpFAsLNPRKTLRSiikepfnthNM-YTMR-------ERNEKVEELLARVGLHPsFAGRYPHE 160
Cdd:PRK11650   72 EPADR-----DIAMVFQN-YA-LYPHMSVRE---------NMaYGLKirgmpkaEIEERVAEAARILELEP-LLDRKPRE 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK11650  135 LSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAE 214

                         250
                  ....*....|..
gi 2181075557 241 ELTGKFELYDNP 252
Cdd:PRK11650  215 QIGTPVEVYEKP 226

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

31-239

1.61e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 106.04 E-value: 1.61e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlsEEKLRKsVRKNIQMVFQDPFAS 110
Cdd:PRK13652   15 GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPIT---KENIRE-VRKFVGLVFQNPDDQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLRSIIKEPFNTH-NMYTMRERnekVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PRK13652   91 IFSPTVEQDIAFGPINLGlDEETVAHR---VSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTA 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2181075557 190 ALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:PRK13652  167 GLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRI 216

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

34-252

1.87e-26

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 104.03 E-value: 1.87e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQDP--FASl 111
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSS----LTIIPQDPtlFSG- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 nprkTLRSIIkEPFnthNMYTmrerNEKVEELLaRV---GLHpsfagrypheFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:cd03369    97 ----TIRSNL-DPF---DEYS----DEEIYGAL-RVsegGLN----------LSQGQRQLLCLARALLKRPRVLVLDEAT 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 189 SALDVSIQAQvinLMEELQEEF-NLTYLFISHDLSVVRHIsDRVGVMYLGKMMEltgkfelYDNP 252
Cdd:cd03369   154 ASIDYATDAL---IQKTIREEFtNSTILTIAHRLRTIIDY-DKILVMDAGEVKE-------YDHP 207

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

7-239

1.89e-26

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 102.90 E-value: 1.89e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKkyfpirsglfqrkVGDvkAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:cd03215     2 EPVLEVRGLS-------------VKG--AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTR 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSeekLRKSVRKNIQMVFQDpfaslnpRKtlrsiikepfnthnmytmrernekveellaRVGLHPSFAGRY----PHEFS 162
Cdd:cd03215    67 RS---PRDAIRAGIAYVPED-------RK------------------------------REGLVLDLSVAEnialSSLLS 106

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03215   107 GGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

1-223

2.64e-26

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 109.43 E-value: 2.64e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   1 MTAanqetILELRDVKKYFPirSGlfqrkVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK 80
Cdd:PRK10535    1 MTA-----LLELKDIRRSYP--SG-----EEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVA 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDISNLSEEKLRKSVRKNIQMVFQdpfaslnpRKTLRSIIKEPFNTH--NMYTMRERNEKVE---ELLARVGLHPSfAG 155
Cdd:PRK10535   69 GQDVATLDADALAQLRREHFGFIFQ--------RYHLLSHLTAAQNVEvpAVYAGLERKQRLLraqELLQRLGLEDR-VE 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 156 RYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNlTYLFISHDLSV 223
Cdd:PRK10535  140 YQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGH-TVIIVTHDPQV 206

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

36-234

3.98e-26

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 108.30 E-value: 3.98e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRK--------------SVRKNIQ 101
Cdd:COG4618   348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRhigylpqdvelfdgTIAENIA 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 102 MvfqdpFASLNPrktlrsiikepfnthnmytmrernEKVEELLARVGLHP---SFAGRY-------PHEFSGGQRQRIGI 171
Cdd:COG4618   428 R-----FGDADP------------------------EKVVAAAKLAGVHEmilRLPDGYdtrigegGARLSGGQRQRIGL 478

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 172 ARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHiSDRVGVM 234
Cdd:COG4618   479 ARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKAR-GATVVVITHRPSLLAA-VDKLLVL 539

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

8-241

4.58e-26

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 103.62 E-value: 4.58e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFPIRSGLFQR-----------KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQ 76
Cdd:COG1134     3 SMIEVENVSKSYRLYHEPSRSlkelllrrrrtRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  77 ILFKGQdISNLSE------EKLrkSVRKNIQMVfqdpfASLnprktlrsiikepfntHNMyTMRERNEKVEELLArvglh 150
Cdd:COG1134    83 VEVNGR-VSALLElgagfhPEL--TGRENIYLN-----GRL----------------LGL-SRKEIDEKFDEIVE----- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 151 psFA--GRYPHE----FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVV 224
Cdd:COG1134   133 --FAelGDFIDQpvktYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSMGAV 209

                         250
                  ....*....|....*..
gi 2181075557 225 RHISDRVGVMYLGKMME 241
Cdd:COG1134   210 RRLCDRAIWLEKGRLVM 226

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

26-241

5.56e-26

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 101.62 E-value: 5.56e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLseeklRKSVRKNIQMVFQ 105
Cdd:cd03247     8 FSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDL-----EKALSSLISVLNQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPFAslnprktlrsiikepFNThnmyTMRERnekveellarVGLhpsfagryphEFSGGQRQRIGIARALTLNPELIIAD 185
Cdd:cd03247    83 RPYL---------------FDT----TLRNN----------LGR----------RFSGGERQRLALARILLQDAPIVLLD 123

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 186 EPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHIsDRVGVMYLGKMME 241
Cdd:cd03247   124 EPTVGLDPITERQLLSLIFEVLK--DKTLIWITHHLTGIEHM-DKILFLENGKIIM 176

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

9-295

5.75e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 105.17 E-value: 5.75e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPIRS----------GLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIL 78
Cdd:COG4586     1 IIEVENLSKTYRVYEkepglkgalkGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  79 FKGQDISnlseeKLRKSVRKNIQMVF-Q------DpfasLNPRKTLRsIIKEpfnthnMY--TMRERNEKVEELLARVGL 149
Cdd:COG4586    81 VLGYVPF-----KRRKEFARRIGVVFgQrsqlwwD----LPAIDSFR-LLKA------IYriPDAEYKKRLDELVELLDL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 HPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISD 229
Cdd:COG4586   145 GE-LLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCD 223

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 230 RVGVMYLGKMmeltgkfeLYDNPLHpytqALlssvpvtRKRGSVKRE-RIVLKGELPSPANPPKGCV 295
Cdd:COG4586   224 RVIVIDHGRI--------IYDGSLE----EL-------KERFGPYKTiVLELAEPVPPLELPRGGEV 271

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

27-252

9.12e-26

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 104.93 E-value: 9.12e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  27 QRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQI-----------LFKGQDISNLSEE-KLRK 94
Cdd:PRK13631   33 EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdiyigdkkNNHELITNPYSKKiKNFK 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  95 SVRKNIQMVFQDPFASLNPRKTLRSIIKEPFNTHnmYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARA 174
Cdd:PRK13631  113 ELRRRVSMVFQFPEYQLFKDTIEKDIMFGPVALG--VKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGI 190

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 175 LTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNP 252
Cdd:PRK13631  191 LAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKAN-NKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQ 267

PRK13549

xylose transporter ATP-binding subunit; Provisional

6-238

9.13e-26

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 106.94 E-value: 9.13e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYkPT---EGQILFKGQ 82
Cdd:PRK13549    2 MEYLLEMKNITKTF-----------GGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHgtyEGEIIFEGE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DisnLSEEKLRKSVRKNIQMVFQDpfASLNPRKTLRSII---KEPfnTHN-------MYtmrernEKVEELLARVGLHPS 152
Cdd:PRK13549   70 E---LQASNIRDTERAGIAIIHQE--LALVKELSVLENIflgNEI--TPGgimdydaMY------LRAQKLLAQLKLDIN 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 153 FAGRYpHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVG 232
Cdd:PRK13549  137 PATPV-GNLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTIC 214


                  ....*.
gi 2181075557 233 VMYLGK 238
Cdd:PRK13549  215 VIRDGR 220

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

2-221

9.31e-26

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 107.45 E-value: 9.31e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   2 TAANQETILELRDVKKYFPirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKG 81
Cdd:TIGR02868 327 AVGLGKPTLELRDLSAGYP----------GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDG 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  82 QDISNLSEEKLRKSVRkniqMVFQDP--FASlnprkTLRSiikepfnthNMYTMRER--NEKVEELLARVGLHPSFAGRy 157
Cdd:TIGR02868 397 VPVSSLDQDEVRRRVS----VCAQDAhlFDT-----TVRE---------NLRLARPDatDEELWAALERVGLADWLRAL- 457

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 158 PH-----------EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMeeLQEEFNLTYLFISHDL 221
Cdd:TIGR02868 458 PDgldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHHL 530

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

7-252

9.68e-26

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 102.75 E-value: 9.68e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:COG0410     1 MPMLEVENLHAGY-----------GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLrksVRKNIQMVFQDP--FASLNPRKTLRsiikepfnthnM--YTMRERnEKVEELLARV-GLHP-------SFA 154
Cdd:COG0410    70 LPPHRI---ARLGIGYVPEGRriFPSLTVEENLL-----------LgaYARRDR-AEVRADLERVyELFPrlkerrrQRA 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 155 GRypheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:COG0410   135 GT----LSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRAYVL 209

                         250
                  ....*....|....*....
gi 2181075557 235 YLGKM-MELTGKfELYDNP 252
Cdd:COG0410   210 ERGRIvLEGTAA-ELLADP 227

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

25-250

1.04e-25

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 103.66 E-value: 1.04e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  25 LFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlseEKLRKSVRKNIQMVF 104
Cdd:PRK13647   10 LHFRYKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVN----AENEKWVRSKVGLVF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 105 QDP----FASlnprktlrSIIKE-PFNTHNM-YTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:PRK13647   86 QDPddqvFSS--------TVWDDvAFGPVNMgLDKDEVERRVEEALKAVRMW-DFRDKPPYHLSYGQKKRVAIAGVLAMD 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYD 250
Cdd:PRK13647  157 PDVIVLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTD 227

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

10-239

1.57e-25

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 101.84 E-value: 1.57e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSGLFQRK-----------VGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIL 78
Cdd:cd03220     1 IELENVSKSYPTYKGGSSSLkklgilgrkgeVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  79 FKGQDISNLS-----EEKLrkSVRKNIQMVfqdpfASLNPRKTlrsiikepfnthnmytmRERNEKVEELLArvglhpsF 153
Cdd:cd03220    81 VRGRVSSLLGlgggfNPEL--TGRENIYLN-----GRLLGLSR-----------------KEIDEKIDEIIE-------F 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 154 A--GRYPHE----FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNlTYLFISHDLSVVRHI 227
Cdd:cd03220   130 SelGDFIDLpvktYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGK-TVILVSHDPSSIKRL 208

                         250
                  ....*....|..
gi 2181075557 228 SDRVGVMYLGKM 239
Cdd:cd03220   209 CDRALVLEKGKI 220

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

31-234

2.26e-25

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 104.92 E-value: 2.26e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEeklrKSVRKNIQMVFQDpfAS 110
Cdd:PRK09536   14 GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSA----RAASRRVASVPQD--TS 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLRSIIKEPFNTH--NMYTMRERNEK-VEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:PRK09536   88 LSFEFDVRQVVEMGRTPHrsRFDTWTETDRAaVERAMERTGV-AQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEP 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:PRK09536  167 TASLDINHQVRTLELVRRLVDD-GKTAVAAIHDLDLAARYCDELVLL 212

NHLM_micro_ABC1

TIGR03796

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...

36-241

2.92e-25

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]

Pssm-ID: 274788 [Multi-domain] Cd Length: 710 Bit Score: 106.18 E-value: 2.92e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVrkniQMVFQDPFASlnpRK 115
Cdd:TIGR03796 495 IENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREVLANSV----AMVDQDIFLF---EG 567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIkepfnthNMY--TMRERNekVEELLARVGLHPSFAGR---YPHE-------FSGGQRQRIGIARALTLNPELII 183
Cdd:TIGR03796 568 TVRDNL-------TLWdpTIPDAD--LVRACKDAAIHDVITSRpggYDAElaegganLSGGQRQRLEIARALVRNPSILI 638

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 184 ADEPVSALDVSIQAQVinlMEELQEEfNLTYLFISHDLSVVRHiSDRVGVMYLGKMME 241
Cdd:TIGR03796 639 LDEATSALDPETEKII---DDNLRRR-GCTCIIVAHRLSTIRD-CDEIIVLERGKVVQ 691

cbiO

PRK13643

energy-coupling factor transporter ATPase;

34-240

4.15e-25

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 102.50 E-value: 4.15e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFASLNP 113
Cdd:PRK13643   20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQFPESQLFE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIikePFNTHNMYTMRERNEKVE-ELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:PRK13643  100 ETVLKDV---AFGPQNFGIPKEKAEKIAaEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLD 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2181075557 193 VSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK13643  177 PKARIEMMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHII 223

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

3-240

8.95e-25

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 104.34 E-value: 8.95e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   3 AANQETILELRDvkkyfpirsgLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ 82
Cdd:COG3845   251 AEPGEVVLEVEN----------LSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEKLRK-------------------SVRKNIqmvfqdpfaslnprkTLRSIIKEPFNTHNMYTMRERNEKVEEL 143
Cdd:COG3845   321 DITGLSPRERRRlgvayipedrlgrglvpdmSVAENL---------------ILGRYRRPPFSRGGFLDRKAIRAFAEEL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 144 LARvglhpsFAGRYPHE------FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFI 217
Cdd:COG3845   386 IEE------FDVRTPGPdtparsLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLI 458

                         250       260
                  ....*....|....*....|...
gi 2181075557 218 SHDLSVVRHISDRVGVMYLGKMM 240
Cdd:COG3845   459 SEDLDEILALSDRIAVMYEGRIV 481

cbiO

PRK13644

energy-coupling factor transporter ATPase;

35-239

1.07e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 100.83 E-value: 1.07e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeKLrKSVRKNIQMVFQDPFASLNPR 114
Cdd:PRK13644   17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFS--KL-QGIRKLVGIVFQNPETQFVGR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KTLRSIIKEPFNThnMYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVS 194
Cdd:PRK13644   94 TVEEDLAFGPENL--CLPPIEIRKRVDRALAEIGLE-KYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPD 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2181075557 195 IQAQVINLMEELQEEfNLTYLFISHDLSVVrHISDRVGVMYLGKM 239
Cdd:PRK13644  171 SGIAVLERIKKLHEK-GKTIVYITHNLEEL-HDADRIIVMDRGKI 213

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

36-239

1.08e-24

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 100.23 E-value: 1.08e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKStagrTMIRL----YKPTEGQILFKGQDISNLSEEKL--RKSV-RKNIQMVFqdPF 108
Cdd:PRK13548   18 LDDVSLTLRPGEVVAILGPNGAGKS----TLLRAlsgeLSPDSGEVRLNGRPLADWSPAELarRRAVlPQHSSLSF--PF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 aslnprkTLRSIIK---EPFNTHNmytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALT------LNP 179
Cdd:PRK13548   92 -------TVEEVVAmgrAPHGLSR----AEDDALVAAALAQVDLAH-LAGRDYPQLSGGEQQRVQLARVLAqlwepdGPP 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:PRK13548  160 RWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRL 219

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

40-262

1.12e-24

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 99.66 E-value: 1.12e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEklrksvRKNIQMVFQDpfASLNPRKTLRS 119
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPS------RRPVSMLFQE--NNLFSHLTVAQ 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 120 IIKEPFNThNMYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQV 199
Cdd:PRK10771   91 NIGLGLNP-GLKLNAAQREKLHAIARQMGIE-DLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEM 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 200 INLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMeltgkfelYDNPlhpyTQALLS 262
Cdd:PRK10771  169 LTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIA--------WDGP----TDELLS 219

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

13-245

7.78e-24

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 101.63 E-value: 7.78e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  13 RDVKKYFPIRSglfqRKVGDV----------KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQ 82
Cdd:COG1129   239 RELEDLFPKRA----AAPGEVvleveglsvgGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGK 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISN-------------LSEEklRK--------SVRKNIQMVFQDPFAS---LNPRktlrsiikepfnthnmytmRERnE 138
Cdd:COG1129   315 PVRIrsprdairagiayVPED--RKgeglvldlSIRENITLASLDRLSRgglLDRR-------------------RER-A 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 139 KVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFIS 218
Cdd:COG1129   373 LAEEYIKRLRIKTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVIS 451

                         250       260
                  ....*....|....*....|....*...
gi 2181075557 219 HDLSVVRHISDRVGVMYLGKMM-ELTGK 245
Cdd:COG1129   452 SELPELLGLSDRILVMREGRIVgELDRE 479

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

36-239

9.57e-24

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 101.66 E-value: 9.57e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSV---RKNIQMvfqdpFASln 112
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIgylPQDVEL-----FPG-- 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 prktlrsIIKEpfnthNMYTMRER--NEKVEELLARVGLHPSFAgRYPHEF-----------SGGQRQRIGIARALTLNP 179
Cdd:TIGR01842 407 -------TVAE-----NIARFGENadPEKIIEAAKLAGVHELIL-RLPDGYdtvigpggatlSGGQRQRIALARALYGDP 473

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHIsDRVGVMYLGKM 239
Cdd:TIGR01842 474 KLVVLDEPNSNLDEEGEQALANAIKALKAR-GITVVVITHRPSLLGCV-DKILVLQDGRI 531

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

5-229

1.04e-23

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 97.91 E-value: 1.04e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKkyfpirsglFQRkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI 84
Cdd:PRK11831    3 SVANLVDMRGVS---------FTR--GNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENI 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEEKLRkSVRKNIQMVFQDP--FASLNPRKTLrsiikepfnthnMYTMRERNEKVEEL--------LARVGLHPSfA 154
Cdd:PRK11831   72 PAMSRSRLY-TVRKRMSMLFQSGalFTDMNVFDNV------------AYPLREHTQLPAPLlhstvmmkLEAVGLRGA-A 137

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 155 GRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISD 229
Cdd:PRK11831  138 KLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIAD 212

PRK13651

cobalt transporter ATP-binding subunit; Provisional

10-271

1.15e-23

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 98.62 E-value: 1.15e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSGLfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:PRK13651    3 IKVKNIVKIFNKKLPT------ELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLR--------------------KSVRKNIQMVFQdpFA--SLNPRKTLRSIIkepFNTHNMYTMR-ERNEKVEELLAR 146
Cdd:PRK13651   77 TKEKekvleklviqktrfkkikkiKEIRRRVGVVFQ--FAeyQLFEQTIEKDII---FGPVSMGVSKeEAKKRAAKYIEL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 147 VGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRH 226
Cdd:PRK13651  152 VGLDESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLDNVLE 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 227 ISDRVGVMYLGKMMELTGKFE-------LYDNPLHPytQALLSSVPVTRKRG 271
Cdd:PRK13651  231 WTKRTIFFKDGKIIKDGDTYDilsdnkfLIENNMEP--PKLLNFVNKLEKKG 280

cbiO

PRK13640

energy-coupling factor transporter ATPase;

7-252

1.21e-23

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 98.33 E-value: 1.21e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKkyfpirsglFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKP---TEGQILFKGQD 83
Cdd:PRK13640    3 DNIVEFKHVS---------FTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDGIT 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISnlseEKLRKSVRKNIQMVFQDP---FASlnprKTLRSIIKepFNTHNMYTMRERNEK-VEELLARVGLhPSFAGRYPH 159
Cdd:PRK13640   74 LT----AKTVWDIREKVGIVFQNPdnqFVG----ATVGDDVA--FGLENRAVPRPEMIKiVRDVLADVGM-LDYIDSEPA 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHiSDRVGVMYLGKM 239
Cdd:PRK13640  143 NLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANM-ADQVLVLDDGKL 221

                         250
                  ....*....|...
gi 2181075557 240 MELTGKFELYDNP 252
Cdd:PRK13640  222 LAQGSPVEIFSKV 234

PTZ00265

multidrug resistance protein (mdr1); Provisional

11-226

1.63e-23

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 101.64 E-value: 1.63e-23

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   11 ELRDVKK--YFPIRSGLFQRKvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFkgQDISNLS 88
Cdd:PTZ00265   376 KLKDIKKiqFKNVRFHYDTRK--DVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIII--NDSHNLK 451

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   89 EEKLrKSVRKNIQMVFQDP-----------------------------------FASLNPRKTLRSIIKEPFN------- 126
Cdd:PTZ00265   452 DINL-KWWRSKIGVVSQDPllfsnsiknnikyslyslkdlealsnyynedgndsQENKNKRNSCRAKCAGDLNdmsnttd 530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  127 THNMYTMRERNEKVEE-----LLARVGLH----------PSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSAL 191
Cdd:PTZ00265   531 SNELIEMRKNYQTIKDsevvdVSKKVLIHdfvsalpdkyETLVGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSL 610

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 2181075557  192 DVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRH 226
Cdd:PTZ00265   611 DNKSEYLVQKTINNLKGNENRITIIIAHRLSTIRY 645

PRK14243

phosphate transporter ATP-binding protein; Provisional

2-262

1.63e-23

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 97.55 E-value: 1.63e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   2 TAANQETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK--PT---EGQ 76
Cdd:PRK14243    3 TLNGTETVLRTENLNVYY-----------GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDliPGfrvEGK 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  77 ILFKGQDISNLSEEKLrkSVRKNIQMVFQ--DPFaslnPRKTLRSIIKEP-FNTH--NMYTMRERN-------EKVEELL 144
Cdd:PRK14243   72 VTFHGKNLYAPDVDPV--EVRRRIGMVFQkpNPF----PKSIYDNIAYGArINGYkgDMDELVERSlrqaalwDEVKDKL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 145 ARVGLhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFnlTYLFISHDLSVV 224
Cdd:PRK14243  146 KQSGL----------SLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQA 213

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2181075557 225 RHISDRV----------GVMYlGKMMELTGKFELYDNPLHPYTQALLS 262
Cdd:PRK14243  214 ARVSDMTaffnveltegGGRY-GYLVEFDRTEKIFNSPQQQATRDYVS 260

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

7-221

1.96e-23

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 96.69 E-value: 1.96e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKkyfpirsglFQRkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQilfkgqDISN 86
Cdd:COG1119     1 DPLLELRNVT---------VRR--GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGN------DVRL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLRKSV---RKNIQMV---FQDPF-ASLNPRKTLRSIIkepFNT---HNMYTMRERnEKVEELLARVGLHpSFAGR 156
Cdd:COG1119    64 FGERRGGEDVwelRKRIGLVspaLQLRFpRDETVLDVVLSGF---FDSiglYREPTDEQR-ERARELLELLGLA-HLADR 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 157 YPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDL 221
Cdd:COG1119   139 PFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHV 203

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

4-240

2.59e-23

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 96.78 E-value: 2.59e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   4 ANQETILELRDVKKYFPIRSGLfqrkvgdvkavDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQD 83
Cdd:PRK10575    6 NHSDTTFALRNVSFRVPGRTLL-----------HPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSEEKLRKSVRKNIQmvfQDPFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPsFAGRYPHEFSG 163
Cdd:PRK10575   75 LESWSSKAFARKVAYLPQ---QLPAAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKP-LAHRLVDSLSG 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK10575  151 GERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227

urea_trans_UrtE

TIGR03410

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...

10-234

2.63e-23

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 96.05 E-value: 2.63e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:TIGR03410   1 LEVSNLNVYY-----------GQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPP 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLrksVRKNIQMVFQ--DPFASLNPRKTLRSiikepfnthNMYTMRERNEKV-EELLArvgLHP---SFAGRYPHEFSG 163
Cdd:TIGR03410  70 HER---ARAGIAYVPQgrEIFPRLTVEENLLT---------GLAALPRRSRKIpDEIYE---LFPvlkEMLGRRGGDLSG 134

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:TIGR03410 135 GQQQQLAIARALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVM 205

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

10-248

2.87e-23

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 100.09 E-value: 2.87e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSE 89
Cdd:PRK11176  342 IEFRNVTFTYPGK---------EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTL 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKS---VRKNIQMvFQDPFA-----SLNPRKTLRSIIKEPFNTHNMytmrERNEKVEEllarvGLHpSFAGRYPHEF 161
Cdd:PRK11176  413 ASLRNQvalVSQNVHL-FNDTIAnniayARTEQYSREQIEEAARMAYAM----DFINKMDN-----GLD-TVIGENGVLL 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 162 SGGQRQRIGIARALTLNPELIIADEPVSALDV----SIQAQvinlMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLG 237
Cdd:PRK11176  482 SGGQRQRIAIARALLRDSPILILDEATSALDTeserAIQAA----LDELQK--NRTSLVIAHRLSTIEK-ADEILVVEDG 554

                         250
                  ....*....|.
gi 2181075557 238 KMMELTGKFEL 248
Cdd:PRK11176  555 EIVERGTHAEL 565

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

34-241

3.39e-23

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 99.90 E-value: 3.39e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQ--DPFASl 111
Cdd:PRK11160  354 PVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQA----ISVVSQrvHLFSA- 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 nprkTLRS--IIKEPfnthnmytmRERNEKVEELLARVGLHPSF------------AGRyphEFSGGQRQRIGIARALTL 177
Cdd:PRK11160  429 ----TLRDnlLLAAP---------NASDEALIEVLQQVGLEKLLeddkglnawlgeGGR---QLSGGEQRRLGIARALLH 492

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 178 NPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHIsDRVGVMYLGKMME 241
Cdd:PRK11160  493 DAPLLLLDEPTEGLDAETERQILELLAEHAQ--NKTVLMITHRLTGLEQF-DRICVMDNGQIIE 553

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

34-238

3.39e-23

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 95.69 E-value: 3.39e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeekLRKSVRKNIQMVFQDP--FASL 111
Cdd:cd03218    14 KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLP---MHKRARLGIGYLPQEAsiFRKL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 NPRKTLRSIIKEPFnthnmYTMRERNEKVEELLARVGLHP---SFAGRypheFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:cd03218    91 TVEENILAVLEIRG-----LSKKEREEKLEELLEEFHITHlrkSKASS----LSGGERRRVEIARALATNPKFLLLDEPF 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 189 SALD-VSIQaQVINLMEELQeEFNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:cd03218   162 AGVDpIAVQ-DIQKIIKILK-DRGIGVLITDHNVRETLSITDRAYIIYEGK 210

GguA

NF040905

sugar ABC transporter ATP-binding protein;

9-241

5.99e-23

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 99.09 E-value: 5.99e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFPirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrtmirLYK------PT---EGQILF 79
Cdd:NF040905    1 ILEMRGITKTFP-----------GVKALDDVNLSVREGEIHALCGENGAGKST-------LMKvlsgvyPHgsyEGEILF 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQ-----DIsnlseeklRKSVRKNIQMVFQD----PFASL-------NPRKTlRSIIKepfnthnmytMRERNEKVEEL 143
Cdd:NF040905   63 DGEvcrfkDI--------RDSEALGIVIIHQElaliPYLSIaeniflgNERAK-RGVID----------WNETNRRAREL 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 144 LARVGLHPSfagryPHEFSG----GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISH 219
Cdd:NF040905  124 LAKVGLDES-----PDTLVTdigvGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISH 197

                         250       260
                  ....*....|....*....|..
gi 2181075557 220 DLSVVRHISDRVGVMYLGKMME 241
Cdd:NF040905  198 KLNEIRRVADSITVLRDGRTIE 219

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

40-239

6.39e-23

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 94.54 E-value: 6.39e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklrkSVRKNIQMVFQDP--FASLNPRKTL 117
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLA------PYQRPVSMLFQENnlFAHLTVRQNI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 118 RSIIKEPFNTHnmytmRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQA 197
Cdd:TIGR01277  92 GLGLHPGLKLN-----AEQQEKVVDAAQQVGI-ADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLRE 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2181075557 198 QVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:TIGR01277 166 EMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKI 207

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

7-202

7.09e-23

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 95.10 E-value: 7.09e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPirsglfQRKVgdvkaVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:COG1137     1 MMTLEAENLVKSYG------KRTV-----VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITH 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 -------------LSEEK--LRK-SVRKNIQMVFQdpfaslnprktLRSIIKEpfnthnmytmrERNEKVEELLARVGLH 150
Cdd:COG1137    70 lpmhkrarlgigyLPQEAsiFRKlTVEDNILAVLE-----------LRKLSKK-----------EREERLEELLEEFGIT 127

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 151 PsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALD---VS-IQAQVINL 202
Cdd:COG1137   128 H-LRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVDpiaVAdIQKIIRHL 182

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

35-221

7.40e-23

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 95.54 E-value: 7.40e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKlrksvrkniQMVFQDpfASLNPR 114
Cdd:PRK11248   16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---------GVVFQN--EGLLPW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KT----------LRSIIKEpfnthnmytmrERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIA 184
Cdd:PRK11248   85 RNvqdnvafglqLAGVEKM-----------QRLEIAHQMLKKVGLE-GAEKRYIWQLSGGQRQRVGIARALAANPQLLLL 152

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2181075557 185 DEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDL 221
Cdd:PRK11248  153 DEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDI 189

bacteriocin_ABC

TIGR01193

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...

34-241

8.52e-23

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]

Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 99.04 E-value: 8.52e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQDPFASLNp 113
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQF----INYLPQEPYIFSG- 562

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 rktlrSIIKepfnthNMYTMRERNEKVEELLARV--------------GLHPSFAgRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:TIGR01193 563 -----SILE------NLLLGAKENVSQDEIWAACeiaeikddienmplGYQTELS-EEGSSISGGQKQRIALARALLTDS 630

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEfnlTYLFISHDLSVVRHiSDRVGVMYLGKMME 241
Cdd:TIGR01193 631 KVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAKQ-SDKIIVLDHGKIIE 688

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

10-240

1.13e-22

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 94.32 E-value: 1.13e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRS----------GLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILF 79
Cdd:cd03267     1 IEVSNLSKSYRVYSkepgligslkSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQDISnlseeKLRKSVRKNIQMVF---QDPFASLNPRKTLRSIikepfntHNMYTM-----RERNEKVEELL--ARVGL 149
Cdd:cd03267    81 AGLVPW-----KRRKKFLRRIGVVFgqkTQLWWDLPVIDSFYLL-------AAIYDLpparfKKRLDELSELLdlEELLD 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 HPSfagrypHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISD 229
Cdd:cd03267   149 TPV------RQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALAR 222

                         250
                  ....*....|.
gi 2181075557 230 RVGVMYLGKMM 240
Cdd:cd03267   223 RVLVIDKGRLL 233

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

51-247

3.12e-22

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 95.33 E-value: 3.12e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  51 IVGESGCGKST-----AGrtmirLYKPTEGQI------LFKGQDISNLSEEKlrksvrKNIQMVFQDpfASLNP----RK 115
Cdd:PRK11144   29 IFGRSGAGKTSlinaiSG-----LTRPQKGRIvlngrvLFDAEKGICLPPEK------RRIGYVFQD--ARLFPhykvRG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIKEpfnthnmyTMRERNEKVEELLarvGLHPsFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSI 195
Cdd:PRK11144   96 NLRYGMAK--------SMVAQFDKIVALL---GIEP-LLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPR 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 196 QAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMeLTGKFE 247
Cdd:PRK11144  164 KRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVK-AFGPLE 214

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

34-258

6.53e-22

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 93.18 E-value: 6.53e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK-----PTEGQILFKGQdisNLSEEKLR-KSVRKNIQMVFQDP 107
Cdd:PRK14258   21 KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNElesevRVEGRVEFFNQ---NIYERRVNlNRLRRQVSMVHPKP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 ----------------FASLNPRKTLRSIIKEPFNTHNMYtmrernEKVEELLARVGLhpsfagryphEFSGGQRQRIGI 171
Cdd:PRK14258   98 nlfpmsvydnvaygvkIVGWRPKLEIDDIVESALKDADLW------DEIKHKIHKSAL----------DLSGGQQQRLCI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 172 ARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMY-----LGKMMELTGKF 246
Cdd:PRK14258  162 ARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKgnenrIGQLVEFGLTK 241

                         250
                  ....*....|..
gi 2181075557 247 ELYDNPLHPYTQ 258
Cdd:PRK14258  242 KIFNSPHDSRTR 253

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

9-238

6.81e-22

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 96.05 E-value: 6.81e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK--PTEGQILFKGQDisn 86
Cdd:TIGR02633   1 LLEMKGIVKTF-----------GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGSP--- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLRKSVRKNIQMVFQDpfASLNPRKT-LRSIIKEPFNTHNMYTMR--ERNEKVEELLARVGLHPSFAGRYPHEFSG 163
Cdd:TIGR02633  67 LKASNIRDTERAGIVIIHQE--LTLVPELSvAENIFLGNEITLPGGRMAynAMYLRAKNLLRELQLDADNVTRPVGDYGG 144

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:TIGR02633 145 GQQQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQ 218

oligo_HPY

pfam08352

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ...

240-307

1.30e-21

Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.

Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 86.69 E-value: 1.30e-21

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 240 MELTGKFELYDNPLHPYTQALLSSVPVTRKRgsvKRERIVLKGELPSPANPPKGCVFHTRCPVAKPIC 307
Cdd:pfam08352   1 VEEGPTDDILENPLHPYTRALLNSVPRLDPP---KRPLYTIPGNVPSLLELPEGCPFAPRCPFATEEC 65

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

41-231

2.34e-21

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 90.68 E-value: 2.34e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  41 FSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGqdisnlseeKLRKSVRKNIQMVFQ-DPFA---------- 109
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAG---------ASPGKGWRHIGYVPQrHEFAwdfpisvaht 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SLNPRKTLRSIIKEPfnthnmytMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:TIGR03771  72 VMSGRTGHIGWLRRP--------CVADFAAVRDALRRVGLT-ELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFT 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2181075557 190 ALDVSIQAQVINLMEELQEEFNlTYLFISHDLSVVRHISDRV 231
Cdd:TIGR03771 143 GLDMPTQELLTELFIELAGAGT-AILMTTHDLAQAMATCDRV 183

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

36-257

3.61e-21

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 91.31 E-value: 3.61e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEG-----QILFKGQDISNLSEEKlrkSVRKNIQMVFQDPfas 110
Cdd:PRK14271   37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNYRDVL---EFRRRVGMLFQRP--- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 lNP-RKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPSFAGRY---PHEFSGGQRQRIGIARALTLNPELIIADE 186
Cdd:PRK14271  111 -NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLsdsPFRLSGGQQQLLCLARTLAVNPEVLLLDE 189

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 187 PVSALDVSIQAQVINLMEELQEEfnLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPLHPYT 257
Cdd:PRK14271  190 PTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAET 258

ycf16

CHL00131

sulfate ABC transporter protein; Validated

8-248

7.57e-21

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 89.70 E-value: 7.57e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKyfpirsglfqrKVGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMirlYKPTEGQILFKGQ 82
Cdd:CHL00131    6 PILEIKNLHA-----------SVNENEILKGLNLSINKGEIHAIMGPNGSGKSTlskviAGHPA---YKILEGDILFKGE 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 DISNLSEEklrKSVRKNIQMVFQDPF--ASLNPRKTLRSIikepFNT-HNMYTMRERN-----EKVEELLARVGLHPSFA 154
Cdd:CHL00131   72 SILDLEPE---ERAHLGIFLAFQYPIeiPGVSNADFLRLA----YNSkRKFQGLPELDpleflEIINEKLKLVGMDPSFL 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 155 GRYPHE-FSGGQRQRIGIARALTLNPELIIADEPVSALDVS---IQAQVINLMEELQEefnlTYLFISHDLSVVRHIS-D 229
Cdd:CHL00131  145 SRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLDIDalkIIAEGINKLMTSEN----SIILITHYQRLLDYIKpD 220

                         250
                  ....*....|....*....
gi 2181075557 230 RVGVMYLGKMMElTGKFEL 248
Cdd:CHL00131  221 YVHVMQNGKIIK-TGDAEL 238

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

7-220

1.11e-20

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 88.68 E-value: 1.11e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYfpIRSGLFQrkvgdVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:PRK10584    4 ENIVEVHHLKKS--VGQGEHE-----LSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEEKLRKSVRKNIQMVFQDpFAsLNPRKTLRSIIKEPFNTHNMyTMRERNEKVEELLARVGLHPSFAgRYPHEFSGGQR 166
Cdd:PRK10584   77 MDEEARAKLRAKHVGFVFQS-FM-LIPTLNALENVELPALLRGE-SSRQSRNGAKALLEQLGLGKRLD-HLPAQLSGGEQ 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHD 220
Cdd:PRK10584  153 QRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHD 206

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

12-250

1.21e-20

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 92.44 E-value: 1.21e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  12 LRDVKKYFPIRSgLFqrkvgdvkavDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKG--------QD 83
Cdd:COG0488     1 LENLSKSFGGRP-LL----------DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKglrigylpQE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 IsNLSEEKlrkSVRKNIQMVFQDPFASLNPRKTLRSIIKEP-------------FNTHNMYTMRERnekVEELLARVGLH 150
Cdd:COG0488    70 P-PLDDDL---TVLDTVLDGDAELRALEAELEELEAKLAEPdedlerlaelqeeFEALGGWEAEAR---AEEILSGLGFP 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 151 PSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDvsIQAqvINLMEELQEEFNLTYLFISHDlsvvRHISDR 230
Cdd:COG0488   143 EEDLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD--LES--IEWLEEFLKNYPGTVLVVSHD----RYFLDR 214

                         250       260
                  ....*....|....*....|.
gi 2181075557 231 VGvmylGKMMELT-GKFELYD 250
Cdd:COG0488   215 VA----TRILELDrGKLTLYP 231

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

28-234

2.96e-20

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 91.00 E-value: 2.96e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLsEEKLrkSVRKNIQMVFQDp 107
Cdd:PRK09700   13 KSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKL-DHKL--AAQLGIGIIYQE- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 faslnprktlRSIIKEPFNTHNMYTMR---------------ERNEKVEELLARVGLHpsfagRYPHEFSG----GQRQR 168
Cdd:PRK09700   89 ----------LSVIDELTVLENLYIGRhltkkvcgvniidwrEMRVRAAMMLLRVGLK-----VDLDEKVAnlsiSHKQM 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 169 IGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:PRK09700  154 LEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVM 218

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

28-230

3.27e-20

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 91.02 E-value: 3.27e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAgRTMIR---LYKPTEGQIL----------------FKGQ------ 82
Cdd:TIGR03269   8 KKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVL-MHVLRgmdQYEPTSGRIIyhvalcekcgyverpsKVGEpcpvcg 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  83 --------DISNLSeEKLRKSVRKNIQMVFQDPFASLNPRKTLRSIIKepfNTHNM-YTMRERNEKVEELLARVGLhpsf 153
Cdd:TIGR03269  87 gtlepeevDFWNLS-DKLRRRIRKRIAIMLQRTFALYGDDTVLDNVLE---ALEEIgYEGKEAVGRAVDLIEMVQL---- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 154 AGRYPH---EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDR 230
Cdd:TIGR03269 159 SHRITHiarDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDK 238

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

39-244

5.60e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 90.50 E-value: 5.60e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeekLRKSVRKNIQMVFQDPFAS-LNPRKTL 117
Cdd:PRK15439  282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALS---TAQRLARGLVYLPEDRQSSgLYLDAPL 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 118 R-SIIKEPFNTHNMYTMRERNEKVEELLAR-VGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSI 195
Cdd:PRK15439  359 AwNVCALTHNRRGFWIKPARENAVLERYRRaLNIKFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSA 438

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2181075557 196 QAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMM-ELTG 244
Cdd:PRK15439  439 RNDIYQLIRSIAAQ-NVAVLFISSDLEEIEQMADRVLVMHQGEISgALTG 487

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

32-240

5.99e-20

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 87.76 E-value: 5.99e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsNLSEEKLRkSVRKNIQMVFQDPFasl 111
Cdd:PRK13638   13 DEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPL-DYSKRGLL-ALRQQVATVFQDPE--- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 nprktlRSIIKEPFNTHNMYTMRERNEKVEELLARV--GLHPSFAGRYPHE----FSGGQRQRIGIARALTLNPELIIAD 185
Cdd:PRK13638   88 ------QQIFYTDIDSDIAFSLRNLGVPEAEITRRVdeALTLVDAQHFRHQpiqcLSHGQKKRVAIAGALVLQARYLLLD 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 186 EPVSALDVSIQAQVINLMEELQEEFNLTyLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK13638  162 EPTAGLDPAGRTQMIAIIRRIVAQGNHV-IISSHDIDLIYEISDAVYVLRQGQIL 215

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

36-226

1.25e-19

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 89.48 E-value: 1.25e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILF-KGQDISNLSeeklrksvrkniqmvfQDPFAslnPR 114
Cdd:COG4178   379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVLFLP----------------QRPYL---PL 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KTLRSIIKEPfNTHNMYTmrerNEKVEELLARVGLhPSFAGRY------PHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:COG4178   440 GTLREALLYP-ATAEAFS----DAELREALEAVGL-GHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLDEAT 513

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2181075557 189 SALDVSIQAQvinLMEELQEEF-NLTYLFISHDLSVVRH 226
Cdd:COG4178   514 SALDEENEAA---LYQLLREELpGTTVISVGHRSTLAAF 549

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

26-239

1.55e-19

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 85.79 E-value: 1.55e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  26 FQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRtmIRLYKPTEGQILFKGQDISnlseeklRKSVRKNI 100
Cdd:cd03234    13 AKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTlldaiSGR--VEGGGTTSGQILFNGQPRK-------PDQFQKCV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 101 QMVFQDPF--ASLNPRKTLRSIIkePFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:cd03234    84 AYVRQDDIllPGLTVRETLTYTA--ILRLPRKSSDAIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWD 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:cd03234   162 PKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEI 222

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

29-234

1.86e-19

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 85.91 E-value: 1.86e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  29 KVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAgRTMI-RLYKPTEGQILFKGQDISNLSEEKLRK--SVRKniqmvfQ 105
Cdd:COG4604    10 RYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTL-LSMIsRLLPPDSGEVLVDGLDVATTPSRELAKrlAILR------Q 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPfaSLNPRKTLRSII---KEPFN----ThnmytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:COG4604    83 EN--HINSRLTVRELVafgRFPYSkgrlT------AEDREIIDEAIAYLDLED-LADRYLDELSGGQRQRAFIAMVLAQD 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 179 PELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:COG4604   154 TDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAM 209

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

31-231

8.54e-19

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 82.67 E-value: 8.54e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGrtmirLYKPTEGQILFKGQD----ISNLSE--EKLRKSVRKN 99
Cdd:NF040873    3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTllkvlAG-----VLRPTSGTVRRAGGArvayVPQRSEvpDSLPLTVRDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 100 IQMVFqdpFASLNPRKTLRsiikepfnthnmytmRERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNP 179
Cdd:NF040873   78 VAMGR---WARRGLWRRLT---------------RDDRAAVDDALERVGLA-DLAGRQLGELSGGQRQRALLAQGLAQEA 138

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:NF040873  139 DLLLLDEPTTGLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRRADPCV 189

PLN03130

ABC transporter C family member; Provisional

38-251

8.69e-19

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 87.49 E-value: 8.69e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvRKNIQMVFQDP--FASlnprk 115
Cdd:PLN03130  1257 GLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDL----RKVLGIIPQAPvlFSG----- 1327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  116 TLRSIIkEPFNTHNMYTMRERNEK--VEELLAR--VGLHP--SFAGrypHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PLN03130  1328 TVRFNL-DPFNEHNDADLWESLERahLKDVIRRnsLGLDAevSEAG---ENFSVGQRQLLSLARALLRRSKILVLDEATA 1403

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557  190 ALDVSIQAQVinlMEELQEEF-NLTYLFISHDLSVVrhI-SDRVGVMYLGKMMELTGKFELYDN 251
Cdd:PLN03130  1404 AVDVRTDALI---QKTIREEFkSCTMLIIAHRLNTI--IdCDRILVLDAGRVVEFDTPENLLSN 1462

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

31-222

1.13e-18

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 84.27 E-value: 1.13e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEeklrKSVRKNIQMVFQDpfAS 110
Cdd:PRK10253   18 GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYAS----KEVARRIGLLAQN--AT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLRSIIKEPFNTHN-MYTM--RERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:PRK10253   92 TPGDITVQELVARGRYPHQpLFTRwrKEDEEAVTKAMQATGI-THLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEP 170

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEFNLTYLFISHDLS 222
Cdd:PRK10253  171 TTWLDISHQIDLLELLSELNREKGYTLAAVLHDLN 205

xylG

TIGR02633

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

7-239

1.93e-18

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 85.65 E-value: 1.93e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPT-EGQILFKGQ--D 83
Cdd:TIGR02633 255 DVILEARNLTCWDVINP--------HRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKpvD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  84 ISNLSeeklrKSVRKNIQMVFQD-------PFASLNPRKTLRSIikepfnthNMYTMRER-NEKVEELLARVGL------ 149
Cdd:TIGR02633 327 IRNPA-----QAIRAGIAMVPEDrkrhgivPILGVGKNITLSVL--------KSFCFKMRiDAAAELQIIGSAIqrlkvk 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 --HPSFA-GRypheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRH 226
Cdd:TIGR02633 394 taSPFLPiGR----LSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLG 468

                         250
                  ....*....|...
gi 2181075557 227 ISDRVGVMYLGKM 239
Cdd:TIGR02633 469 LSDRVLVIGEGKL 481

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

10-239

2.47e-18

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 81.44 E-value: 2.47e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSGLFQRKVgdvkaVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMirlYKPTEGQILFKGQDI 84
Cdd:cd03213     4 LSFRNLTVTVKSSPSKSGKQL-----LKNVSGKAKPGELTAIMGPSGAGKSTllnalAGRRT---GLGVSGEVLINGRPL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SnlseeklRKSVRKNIQMVFQDP--FASLNPRKTLrsiikepfnthnMYTMRERnekveellarvGLhpsfagryphefS 162
Cdd:cd03213    76 D-------KRSFRKIIGYVPQDDilHPTLTVRETL------------MFAAKLR-----------GL------------S 113

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLS-VVRHISDRVGVMYLGKM 239
Cdd:cd03213   114 GGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT-GRTIICSIHQPSsEIFELFDKLLLLSQGRV 190

PRK10762

D-ribose transporter ATP binding protein; Provisional

7-238

3.40e-18

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 85.06 E-value: 3.40e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:PRK10762    2 QALLQLKGIDKAFP-----------GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTF 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSEeklRKSVRKNIQMVFQDpfasLN--PRKTLRSII---KEPFNTHNMYTMRERNEKVEELLARVGLhpSFAGRYP-HE 160
Cdd:PRK10762   71 NGP---KSSQEAGIGIIHQE----LNliPQLTIAENIflgREFVNRFGRIDWKKMYAEADKLLARLNL--RFSSDKLvGE 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:PRK10762  142 LSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQ 218

PRK13549

xylose transporter ATP-binding subunit; Provisional

7-246

3.83e-18

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 84.98 E-value: 3.83e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSGlfqrkvgdVKAVDGVSFSLKKGETLGIVGESGcgkstAGRT--MIRLYKP----TEGQILFK 80
Cdd:PRK13549  257 EVILEVRNLTAWDPVNPH--------IKRVDDVSFSLRRGEILGIAGLVG-----AGRTelVQCLFGAypgrWEGEIFID 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQ--DISNLseeklRKSVRKNIQMVFQD-------PFASLNPRKTLRSIIKepFNTHNMYTMRERNEKVEELLARVGL-- 149
Cdd:PRK13549  324 GKpvKIRNP-----QQAIAQGIAMVPEDrkrdgivPVMGVGKNITLAALDR--FTGGSRIDDAAELKTILESIQRLKVkt 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 150 -HPSFA-GRypheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHI 227
Cdd:PRK13549  397 aSPELAiAR----LSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGL 471

                         250
                  ....*....|....*....
gi 2181075557 228 SDRVGVMYLGKmmeLTGKF 246
Cdd:PRK13549  472 SDRVLVMHEGK---LKGDL 487

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

12-252

6.76e-18

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 83.16 E-value: 6.76e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  12 LRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEK 91
Cdd:PRK11000    6 LRNVTKAY-----------GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  92 lrksvrKNIQMVFQDpFAsLNPRKTLrsiikepfnTHNM-YTMR-------ERNEKVEELlARVGLHPSFAGRYPHEFSG 163
Cdd:PRK11000   75 ------RGVGMVFQS-YA-LYPHLSV---------AENMsFGLKlagakkeEINQRVNQV-AEVLQLAHLLDRKPKALSG 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 164 GQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELT 243
Cdd:PRK11000  137 GQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216


                  ....*....
gi 2181075557 244 GKFELYDNP 252
Cdd:PRK11000  217 KPLELYHYP 225

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

10-233

8.39e-18

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 83.81 E-value: 8.39e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdisnlse 89
Cdd:PRK11288    5 LSFDGIGKTFP-----------GVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQ------- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklrksvrkniQMVFQDPFASLN-------------PRKTLRSII---KEPfNTHNMYTMRERNEKVEELLARVGLH--P 151
Cdd:PRK11288   67 -----------EMRFASTTAALAagvaiiyqelhlvPEMTVAENLylgQLP-HKGGIVNRRLLNYEAREQLEHLGVDidP 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 152 SFAGRYpheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRV 231
Cdd:PRK11288  135 DTPLKY---LSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAI 210


                  ..
gi 2181075557 232 GV 233
Cdd:PRK11288  211 TV 212

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

38-205

1.07e-17

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 79.92 E-value: 1.07e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI--SNLSEE----------KLRKSVRKNIQmvFQ 105
Cdd:PRK13539   20 GLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIddPDVAEAchylghrnamKPALTVAENLE--FW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 DPFaslnprktlrsiikepFNTHNmytmrernEKVEELLARVGLHPSFAGRYpHEFSGGQRQRIGIARALTLNPELIIAD 185
Cdd:PRK13539   98 AAF----------------LGGEE--------LDIAAALEAVGLAPLAHLPF-GYLSAGQKRRVALARLLVSNRPIWILD 152

                         170       180
                  ....*....|....*....|
gi 2181075557 186 EPVSALDVSIQAQVINLMEE 205
Cdd:PRK13539  153 EPTAALDAAAVALFAELIRA 172

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

8-231

2.34e-17

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 82.42 E-value: 2.34e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnl 87
Cdd:COG0488   314 KVLELEGLSKSY-----------GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV---------- 372

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 seeklrkSVRKNIQMVF--QDpFASLNPRKTLRSIIKEpfnthnmYTMRERNEKVEELLARVGLHPSFAGRYPHEFSGGQ 165
Cdd:COG0488   373 -------KLGETVKIGYfdQH-QEELDPDKTVLDELRD-------GAPGGTEQEVRGYLGRFLFSGDDAFKPVGVLSGGE 437

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 166 RQRIGIARALTLNPELIIADEPVSALDVsiqaQVINLMEELQEEFNLTYLFISHDLSVVRHISDRV 231
Cdd:COG0488   438 KARLALAKLLLSPPNVLLLDEPTNHLDI----ETLEALEEALDDFPGTVLLVSHDRYFLDRVATRI 499

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

38-203

3.09e-17

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 78.69 E-value: 3.09e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlseeKLRKSVRKNIQMVFQDPF--ASLNPRK 115
Cdd:cd03231    18 GLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLD-----FQRDSIARGLLYLGHAPGikTTLSVLE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRsiIKEPFNThnmytmrerNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSI 195
Cdd:cd03231    93 NLR--FWHADHS---------DEQVEEALARVGLN-GFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160


                  ....*...
gi 2181075557 196 QAQVINLM 203
Cdd:cd03231   161 VARFAEAM 168

PRK09984

phosphonate ABC transporter ATP-binding protein;

34-251

2.16e-16

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 77.75 E-value: 2.16e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLY---KPTEGQILFKGQDISNlsEEKLRKSVRKN---IQMVFQDp 107
Cdd:PRK09984   18 QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVQR--EGRLARDIRKSranTGYIFQQ- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 FASLNPRKTLRSII-----KEPF-NTHNMYTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPEL 181
Cdd:PRK09984   95 FNLVNRLSVLENVLigalgSTPFwRTCFSWFTREQKQRALQALTRVGM-VHFAHQRVSTLSGGQQQRVAIARALMQQAKV 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 182 IIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMeLTGKFELYDN 251
Cdd:PRK09984  174 ILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVF-YDGSSQQFDN 242

PLN03232

ABC transporter C family member; Provisional

38-265

2.19e-16

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 80.41 E-value: 2.19e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSvrknIQMVFQDP--FASlnprk 115
Cdd:PLN03232  1254 GLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRV----LSIIPQSPvlFSG----- 1324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  116 TLRSIIkEPFNTHNMYTMRERNEK--VEELLAR--VGLHPS-FAGryPHEFSGGQRQRIGIARALTLNPELIIADEPVSA 190
Cdd:PLN03232  1325 TVRFNI-DPFSEHNDADLWEALERahIKDVIDRnpFGLDAEvSEG--GENFSVGQRQLLSLARALLRRSKILVLDEATAS 1401

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557  191 LDVSIQAQVinlMEELQEEF-NLTYLFISHDLSVVRHiSDRVGVMYLGKMMELTGKFELYDNPLHPYTQALLSSVP 265
Cdd:PLN03232  1402 VDVRTDSLI---QRTIREEFkSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTGP 1473

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

39-247

2.73e-16

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 79.50 E-value: 2.73e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKSTagrtMIRL---YKPTEGQILFKGQDISNLSEEklrkSVRKNIQMVFQDPfaSLnPRK 115
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTS----LLNAllgFLPYQGSLKINGIELRELDPE----SWRKHLSWVGQNP--QL-PHG 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIKepFNTHNMytmreRNEKVEELLARVGLHpSFAGRYPH-----------EFSGGQRQRIGIARALTLNPELIIA 184
Cdd:PRK11174  438 TLRDNVL--LGNPDA-----SDEQLQQALENAWVS-EFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLL 509

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 185 DEPVSALDVSIQAQVinlMEELQEE-FNLTYLFISHDLSVVRHIsDRVGVMYLGKMMElTGKFE 247
Cdd:PRK11174  510 DEPTASLDAHSEQLV---MQALNAAsRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQ-QGDYA 568

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

31-245

3.26e-16

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 76.84 E-value: 3.26e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksVRKNIQMVFQdpfas 110
Cdd:PRK11614   16 GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKI---MREAVAIVPE----- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 lNPRKTLRSIIKEPFNTHNMYTMR----ERNEKVEELLARvgLHPSFAGRyPHEFSGGQRQRIGIARALTLNPELIIADE 186
Cdd:PRK11614   88 -GRRVFSRMTVEENLAMGGFFAERdqfqERIKWVYELFPR--LHERRIQR-AGTMSGGEQQMLAIGRALMSQPRLLLLDE 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 187 PVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM-MELTGK 245
Cdd:PRK11614  164 PSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVvLEDTGD 222

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

37-205

7.60e-16

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 74.84 E-value: 7.60e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  37 DGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLR-----------KSVrkniqmvfq 105
Cdd:PRK13538   18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQdllylghqpgiKTE--------- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dpfasLNPRKTLRsiikepFNT--HNMYTmrerNEKVEELLARVGLhpsfAGR--YP-HEFSGGQRQRIGIARALTLNPE 180
Cdd:PRK13538   89 -----LTALENLR------FYQrlHGPGD----DEALWEALAQVGL----AGFedVPvRQLSAGQQRRVALARLWLTRAP 149

                         170       180
                  ....*....|....*....|....*
gi 2181075557 181 LIIADEPVSALDVSIQAQVINLMEE 205
Cdd:PRK13538  150 LWILDEPFTAIDKQGVARLEALLAQ 174

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

9-250

8.18e-16

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 77.78 E-value: 8.18e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirSGlfqrkvgdVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLS 88
Cdd:PRK15439   11 LLCARSISKQY---SG--------VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 EEKLRKSvrkNIQMVFQDPFasLNPRKTLRSIIkepfnTHNMYTMRERNEKVEELLARVGLHPSfagryPHEFSG----G 164
Cdd:PRK15439   80 PAKAHQL---GIYLVPQEPL--LFPNLSVKENI-----LFGLPKRQASMQKMKQLLAALGCQLD-----LDSSAGslevA 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMMeLTG 244
Cdd:PRK15439  145 DRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIA-LSG 222


                  ....*.
gi 2181075557 245 KFELYD 250
Cdd:PRK15439  223 KTADLS 228

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

38-205

1.05e-15

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 74.32 E-value: 1.05e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEE--------------KLRKSVRKNIQmv 103
Cdd:TIGR01189  18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEphenilylghlpglKPELSALENLH-- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 104 FQDPFASLNPRKtlrsiikepfnthnmytmrernekVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELII 183
Cdd:TIGR01189  96 FWAAIHGGAQRT------------------------IEDALAAVGLT-GFEDLPAAQLSAGQQRRLALARLWLSRRPLWI 150

                         170       180
                  ....*....|....*....|..
gi 2181075557 184 ADEPVSALDVSIQAQVINLMEE 205
Cdd:TIGR01189 151 LDEPTTALDKAGVALLAGLLRA 172

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

31-231

1.28e-15

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 75.15 E-value: 1.28e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILfkgqdisnlSEEKLRksvrknIQMVFQdpfaS 110
Cdd:PRK09544   15 GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK---------RNGKLR------IGYVPQ----K 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLrsiikePFNTHNMYTMRERNEKVEELLARVGLHPSFAGRYP-HEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PRK09544   76 LYLDTTL------PLTVNRFLRLRPGTKKEDILPALKRVQAGHLIDAPmQKLSGGETQRVLLARALLNRPQLLVLDEPTQ 149

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2181075557 190 ALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRV 231
Cdd:PRK09544  150 GVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEV 191

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

42-233

2.36e-15

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 74.37 E-value: 2.36e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  42 SLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIL-------FKGQDISNLSEEKLRKSVRKNIQMVFQDPFaslnpr 114
Cdd:cd03237    21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEieldtvsYKPQYIKADYEGTVRDLLSSITKDFYTHPY------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 ktlrsiikepFNTHNMYTMrerneKVEELLARvglhpsfagRYPhEFSGGQRQRIGIARALTLNPELIIADEPVSALDVS 194
Cdd:cd03237    95 ----------FKTEIAKPL-----QIEQILDR---------EVP-ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVE 149

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2181075557 195 IQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGV 233
Cdd:cd03237   150 QRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIV 188

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

34-240

2.80e-15

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 74.16 E-value: 2.80e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  34 KAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeekLRKSVRKNIQMVFQDpfASLNP 113
Cdd:PRK10895   17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLP---LHARARRGIGYLPQE--ASIFR 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLhPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:PRK10895   92 RLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHI-EHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDP 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2181075557 194 SIQAQVINLMEELQeEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK10895  171 ISVIDIKRIIEHLR-DSGLGVLITDHNVRETLAVCERAYIVSQGHLI 216

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

5-242

3.14e-15

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 75.98 E-value: 3.14e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   5 NQETILELRDVKKYfpirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI 84
Cdd:PRK09700  261 AHETVFEVRNVTSR-------------DRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDI 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEeklRKSVRKNIQMV--------FQDPFASLNPRKTLRSIIKEPFN-THNMYTMRERNEKVEELLARVGLHPSFAG 155
Cdd:PRK09700  328 SPRSP---LDAVKKGMAYItesrrdngFFPNFSIAQNMAISRSLKDGGYKgAMGLFHEVDEQRTAENQRELLALKCHSVN 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 156 RYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:PRK09700  405 QNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADD-GKVILMVSSELPEIITVCDRIAVFC 483


                  ....*..
gi 2181075557 236 LGKMMEL 242
Cdd:PRK09700  484 EGRLTQI 490

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

31-192

4.79e-15

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 74.87 E-value: 4.79e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSeeklrKSVRKNIQMVFQdpFAS 110
Cdd:PRK13536   52 GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARA-----RLARARIGVVPQ--FDN 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLRSIIKEPFNTHNMYTmRERNEKVEELLARVGLHPSFAGRYPhEFSGGQRQRIGIARALTLNPELIIADEPVSA 190
Cdd:PRK13536  125 LDLEFTVRENLLVFGRYFGMST-REIEAVIPSLLEFARLESKADARVS-DLSGGMKRRLTLARALINDPQLLILDEPTTG 202


                  ..
gi 2181075557 191 LD 192
Cdd:PRK13536  203 LD 204

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

32-222

4.89e-15

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 75.52 E-value: 4.89e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvRKNIQMVFQDPFasL 111
Cdd:PRK10789  327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSW----RSRLAVVSQTPF--L 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 NPRKTLRSI-IKEPFNTHnmytmrernEKVEEL--LARVglHPSFAgRYPHEF-----------SGGQRQRIGIARALTL 177
Cdd:PRK10789  401 FSDTVANNIaLGRPDATQ---------QEIEHVarLASV--HDDIL-RLPQGYdtevgergvmlSGGQKQRISIARALLL 468

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2181075557 178 NPELIIADEPVSALDVSIQAQVI-NLMEELQEEfnlTYLFISHDLS 222
Cdd:PRK10789  469 NAEILILDDALSAVDGRTEHQILhNLRQWGEGR---TVIISAHRLS 511

PRK15056

manganese/iron ABC transporter ATP-binding protein;

35-240

7.95e-15

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 73.38 E-value: 7.95e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlseeklRKSVRKN-IQMVFQDPFASLNP 113
Cdd:PRK15056   22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT--------RQALQKNlVAYVPQSEEVDWSF 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLRSIIKEPFNTHnMYTMR----ERNEKVEELLARVGLHpSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PRK15056   94 PVLVEDVVMMGRYGH-MGWLRrakkRDRQIVTAALARVDMV-EFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFT 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 190 ALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVgVMYLGKMM 240
Cdd:PRK15056  172 GVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYT-VMVKGTVL 220

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

7-192

9.10e-15

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 73.69 E-value: 9.10e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:PRK13537    5 VAPIDFRNVEKRY-----------GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 LSeeklrKSVRKNIQMVFQdpFASLNPRKTLRSIIKePFNTHNMYTMRERNEKVEELLARVGLHpSFAGRYPHEFSGGQR 166
Cdd:PRK13537   74 RA-----RHARQRVGVVPQ--FDNLDPDFTVRENLL-VFGRYFGLSAAAARALVPPLLEFAKLE-NKADAKVGELSGGMK 144

                         170       180
                  ....*....|....*....|....*.
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALD 192
Cdd:PRK13537  145 RRLTLARALVNDPDVLVLDEPTTGLD 170

PRK10762

D-ribose transporter ATP binding protein; Provisional

36-246

1.57e-14

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 73.88 E-value: 1.57e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGcgkstAGRT--MIRLY---KPTEGQILFKGQDISN-------------LSEEK------ 91
Cdd:PRK10762  268 VNDVSFTLRKGEILGVSGLMG-----AGRTelMKVLYgalPRTSGYVTLDGHEVVTrspqdglangivyISEDRkrdglv 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  92 LRKSVRKNIQMVFQDPFASLN-------PRKTLRSIIKEpFNThnmytmrerneKVEELLARVGLhpsfagrypheFSGG 164
Cdd:PRK10762  343 LGMSVKENMSLTALRYFSRAGgslkhadEQQAVSDFIRL-FNI-----------KTPSMEQAIGL-----------LSGG 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKmmeLTG 244
Cdd:PRK10762  400 NQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGR---ISG 475


                  ..
gi 2181075557 245 KF 246
Cdd:PRK10762  476 EF 477

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

42-233

1.72e-14

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 74.05 E-value: 1.72e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  42 SLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQ------ILFKGQDISNLSEEklrkSVRKNIQMVFQDPFASlnprK 115
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEvdedlkISYKPQYISPDYDG----TVEEFLRSANTDDFGS----S 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 TLRSIIKEPFNTHNMYtmrERNekVEELlarvglhpsfagryphefSGGQRQRIGIARALTLNPELIIADEPVSALDVSI 195
Cdd:COG1245   434 YYKTEIIKPLGLEKLL---DKN--VKDL------------------SGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQ 490

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2181075557 196 QAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGV 233
Cdd:COG1245   491 RLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMV 528

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

40-219

1.85e-14

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 69.88 E-value: 1.85e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnlseeklRKSVRKNIQMVFQDPFAslnPRKTLRS 119
Cdd:cd03223    21 SFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRI---------------GMPEGEDLLFLPQRPYL---PLGTLRE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 120 IIkepfnthnmytmrernekveellarvglhpsfagRYP--HEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQA 197
Cdd:cd03223    83 QL----------------------------------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESED 128

                         170       180
                  ....*....|....*....|..
gi 2181075557 198 QvinLMEELQEEFnLTYLFISH 219
Cdd:cd03223   129 R---LYQLLKELG-ITVISVGH 146

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

28-192

1.86e-14

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 74.01 E-value: 1.86e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  28 RKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTagrTM---IRLYKPTEGQILFKGQ--DISNLSeekLRK-------- 94
Cdd:NF033858  274 MRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKST---TMkmlTGLLPASEGEAWLFGQpvDAGDIA---TRRrvgymsqa 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  95 -------SVRKNIQM---VFQDPFASLNPRktlrsiikepfnthnmytmrernekVEELLARVGLHPsFAGRYPHEFSGG 164
Cdd:NF033858  348 fslygelTVRQNLELharLFHLPAAEIAAR-------------------------VAEMLERFDLAD-VADALPDSLPLG 401

                         170       180
                  ....*....|....*....|....*...
gi 2181075557 165 QRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:NF033858  402 IRQRLSLAVAVIHKPELLILDEPTSGVD 429

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

32-226

3.39e-14

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 70.44 E-value: 3.39e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  32 DVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFQDPFAsL 111
Cdd:cd03290    13 GLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWL-L 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 112 NPRKTLRSIIKEPFNthnmytmRERNEKVEE---LLARVGLHP----SFAGRYPHEFSGGQRQRIGIARALTLNPELIIA 184
Cdd:cd03290    92 NATVEENITFGSPFN-------KQRYKAVTDacsLQPDIDLLPfgdqTEIGERGINLSGGQRQRICVARALYQNTNIVFL 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2181075557 185 DEPVSALDVSIQAQVIN--LMEELQEEfNLTYLFISHDLSVVRH 226
Cdd:cd03290   165 DDPFSALDIHLSDHLMQegILKFLQDD-KRTLVLVTHKLQYLPH 207

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

40-233

3.45e-14

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 73.30 E-value: 3.45e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSL-------KKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnlsEEKLRKSVRKniQMVFQDPFASLn 112
Cdd:PRK13409  352 DFSLeveggeiYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV-----------DPELKISYKP--QYIKPDYDGTV- 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 pRKTLRSIiKEPFNTHNMYTmrernekveELLARVGLHPSFaGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:PRK13409  418 -EDLLRSI-TDDLGSSYYKS---------EIIKPLQLERLL-DKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2181075557 193 VSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGV 233
Cdd:PRK13409  486 VEQRLAVAKAIRRIAEEREATALVVDHDIYMIDYISDRLMV 526

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

35-241

5.59e-14

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 72.44 E-value: 5.59e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGET--------------LGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSVrkni 100
Cdd:PRK10790  342 DIDNVSFAYRDDNLvlqninlsvpsrgfVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGV---- 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 101 QMVFQDPF---ASLNPRKTLRSIIKEpfnthnmytmrernEKVEELLARV-----------GLHpSFAGRYPHEFSGGQR 166
Cdd:PRK10790  418 AMVQQDPVvlaDTFLANVTLGRDISE--------------EQVWQALETVqlaelarslpdGLY-TPLGEQGNNLSVGQK 482

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHiSDRVGVMYLGKMME 241
Cdd:PRK10790  483 QLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVRE--HTTLVVIAHRLSTIVE-ADTILVLHRGQAVE 554

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

30-248

8.14e-14

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 70.21 E-value: 8.14e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  30 VGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMI--RLYKPTEGQILFKGQDISNLSEEKlrkSVRKNIQMVFQDP 107
Cdd:PRK09580   11 VEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPED---RAGEGIFMAFQYP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 108 F------------ASLNPRKTLRSiiKEPFNTHNMYTMRErnEKV------EELLAR---VGlhpsfagrypheFSGGQR 166
Cdd:PRK09580   88 VeipgvsnqfflqTALNAVRSYRG--QEPLDRFDFQDLME--EKIallkmpEDLLTRsvnVG------------FSGGEK 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHIS-DRVGVMYLGKMMElTGK 245
Cdd:PRK09580  152 KRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDG-KRSFIIVTHYQRILDYIKpDYVHVLYQGRIVK-SGD 229


                  ...
gi 2181075557 246 FEL 248
Cdd:PRK09580  230 FTL 232

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

11-238

1.23e-13

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 68.83 E-value: 1.23e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  11 ELRDVKKYFPIRSGLFQRKVgdvkaVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKgqdisnlsee 90
Cdd:COG2401    26 RVAIVLEAFGVELRVVERYV-----LRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVD---------- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  91 klrksvrkniqmVFQDPFaslnPRKtlRSIIKepfnthNMYTMRERNEKVEeLLARVGLH-PSFAGRYPHEFSGGQRQRI 169
Cdd:COG2401    91 ------------VPDNQF----GRE--ASLID------AIGRKGDFKDAVE-LLNAVGLSdAVLWLRRFKELSTGQKFRF 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 170 GIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVgVMYLGK 238
Cdd:COG2401   146 RLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDL-LIFVGY 213

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

10-231

3.67e-13

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 65.93 E-value: 3.67e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnlse 89
Cdd:cd03221     1 IELENLSKTY-----------GGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV------------ 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklrksvrkniqmvfqdpfaslnprktlrsiikepfnthnmytmrERNEKVeellaRVGlhpsfagrYPHEFSGGQRQRI 169
Cdd:cd03221    58 ---------------------------------------------TWGSTV-----KIG--------YFEQLSGGEKMRL 79

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 170 GIARALTLNPELIIADEPVSALDV-SIQAqvinLMEELQeEFNLTYLFISHDLSVVRHISDRV 231
Cdd:cd03221    80 ALAKLLLENPNLLLLDEPTNHLDLeSIEA----LEEALK-EYPGTVILVSHDRYFLDQVATKI 137

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

12-238

4.26e-13

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 69.76 E-value: 4.26e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  12 LRDVKKYFPirsglfqrkvgDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsNLSEEK 91
Cdd:PRK10982    1 MSNISKSFP-----------GVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-DFKSSK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  92 lrKSVRKNIQMVFQDpfasLNPRKTlRSII----------KEPFNTHN-MYtmRERNEKVEELLARVGLHPSFAgryphE 160
Cdd:PRK10982   69 --EALENGISMVHQE----LNLVLQ-RSVMdnmwlgryptKGMFVDQDkMY--RDTKAIFDELDIDIDPRAKVA-----T 134

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 161 FSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGK 238
Cdd:PRK10982  135 LSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKER-GCGIVYISHKMEEIFQLCDEITILRDGQ 211

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

36-240

7.92e-13

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 67.17 E-value: 7.92e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKST-----AGRTmirlykPTEGQILFKGQDISNLSEEKLRK-------SVRKNIQM- 102
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTllarmAGLL------PGQGEILLNGRPLSDWSAAELARhraylsqQQSPPFAMp 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 103 VFQdpFASLNPRKTLRSiikepfnthnmytmrERNEK-VEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARAL-----T 176
Cdd:COG4138    86 VFQ--YLALHQPAGASS---------------EAVEQlLAQLAEALGLED-KLSRPLTQLSGGEWQRVRLAAVLlqvwpT 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557 177 LNPE--LIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLS-VVRHiSDRVGVMYLGKMM 240
Cdd:COG4138   148 INPEgqLLLLDEPMNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNhTLRH-ADRVWLLKQGKLV 212

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

38-206

1.25e-12

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 68.54 E-value: 1.25e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKST-----AGRTMIRLYKptEGQILFKGQDIsNLSEEKLRKSvrkniqMVFQDP--FAS 110
Cdd:TIGR00955  43 NVSGVAKPGELLAVMGSSGAGKTTlmnalAFRSPKGVKG--SGSVLLNGMPI-DAKEMRAISA------YVQQDDlfIPT 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLrsIIKEPFNTHNMYTMRERNEKVEELLARVGLHPS------FAGRYpHEFSGGQRQRIGIARALTLNPELIIA 184
Cdd:TIGR00955 114 LTVREHL--MFQAHLRMPRRVTKKEKRERVDEVLQALGLRKCantrigVPGRV-KGLSGGERKRLAFASELLTDPPLLFC 190

                         170       180
                  ....*....|....*....|..
gi 2181075557 185 DEPVSALDVSIQAQVINLMEEL 206
Cdd:TIGR00955 191 DEPTSGLDSFMAYSVVQVLKGL 212

PRK03695

vitamin B12-transporter ATPase; Provisional

39-239

1.48e-12

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 66.49 E-value: 1.48e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKST-----AGRTmirlykPTEGQILFKGQDISNLSEEKLRK-------SVRKNIQM-VFQ 105
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTllarmAGLL------PGSGSIQFAGQPLEAWSAAELARhraylsqQQTPPFAMpVFQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dpFASLNprktlrsiikEPFNTHNmytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARAL-----TLNPE 180
Cdd:PRK03695   89 --YLTLH----------QPDKTRT----EAVASALNEVAEALGLDD-KLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPA 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 181 --LIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKM 239
Cdd:PRK03695  152 gqLLLLDEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKL 211

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

40-235

2.64e-12

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 65.85 E-value: 2.64e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSL------KKGETLGIVGESGCGKSTAGR--------------------TMIRLYKPTEGQILFKgqdisNLSEEKLR 93
Cdd:cd03236    14 SFKLhrlpvpREGQVLGLVGPNGIGKSTALKilagklkpnlgkfddppdwdEILDEFRGSELQNYFT-----KLLEGDVK 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  94 KSVRKniQMVFQDPfaslnprKTLRSiikepfNTHNMYTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIAR 173
Cdd:cd03236    89 VIVKP--QYVDLIP-------KAVKG------KVGELLKKKDERGKLDELVDQLELRH-VLDRNIDQLSGGELQRVAIAA 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 174 ALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNlTYLFISHDLSVVRHISDRVGVMY 235
Cdd:cd03236   153 ALARDADFYFFDEPSSYLDIKQRLNAARLIRELAEDDN-YVLVVEHDLAVLDYLSDYIHCLY 213

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

38-234

7.54e-12

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 63.64 E-value: 7.54e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdISNLSEEK--LRKSVRKNIqmVFQDPFaslnprk 115
Cdd:cd03250    23 DINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-IAYVSQEPwiQNGTIRENI--LFGKPF------- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 116 tlrsiikepfnthnmytmreRNEKVEELLARVGLHPSFAgRYPH-------E----FSGGQRQRIGIARALTLNPELIIA 184
Cdd:cd03250    93 --------------------DEERYEKVIKACALEPDLE-ILPDgdlteigEkginLSGGQKQRISLARAVYSDADIYLL 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 185 DEPVSALDVSIQAQVIN--LMEELQEefNLTYLFISHDLSVVRHiSDRVGVM 234
Cdd:cd03250   152 DDPLSAVDAHVGRHIFEncILGLLLN--NKTRILVTHQLQLLPH-ADQIVVL 200

PTZ00265

multidrug resistance protein (mdr1); Provisional

39-233

8.72e-12

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 66.21 E-value: 8.72e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYK-PTEGQILFKGQDISNLSEEKLRK-SVRKNIQMVFQDPFAS------ 110
Cdd:PTZ00265  1187 LTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDlKNDHHIVFKNEHTNDMTNEQDYQgDEEQNVGMKNVNEFSLtkeggs 1266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  111 ------------------------LNPRKTLRSII-KEP--FNT---HNMYTMRER---------------NEKVEELLA 145
Cdd:PTZ00265  1267 gedstvfknsgkilldgvdicdynLKDLRNLFSIVsQEPmlFNMsiyENIKFGKEDatredvkrackfaaiDEFIESLPN 1346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  146 RvglHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVR 225
Cdd:PTZ00265  1347 K---YDTNVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIK 1423


                   ....*...
gi 2181075557  226 HiSDRVGV 233
Cdd:PTZ00265  1424 R-SDKIVV 1430

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

21-250

9.13e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 66.12 E-value: 9.13e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   21 IRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdISNLSEEKLRK--SVRK 98
Cdd:TIGR00957  639 VHNATFTWARDLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-VAYVPQQAWIQndSLRE 717

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   99 NIqmVFQDPfasLNPrKTLRSIIKEPfnthnmytmrernekveELLARVGLHPSF----AGRYPHEFSGGQRQRIGIARA 174
Cdd:TIGR00957  718 NI--LFGKA---LNE-KYYQQVLEAC-----------------ALLPDLEILPSGdrteIGEKGVNLSGGQKQRVSLARA 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  175 LTLNPELIIADEPVSALDV----SIQAQVINLMEELQeefNLTYLFISHDLSVVRHIsDRVGVMYLGKMMELTGKFELYD 250
Cdd:TIGR00957  775 VYSNADIYLFDDPLSAVDAhvgkHIFEHVIGPEGVLK---NKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQ 850

PTZ00243

ABC transporter; Provisional

38-252

9.66e-12

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 65.96 E-value: 9.66e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   38 GVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRK--------------SVRKNIqmv 103
Cdd:PTZ00243  1328 GVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRqfsmipqdpvlfdgTVRQNV--- 1404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  104 fqDPFASLNPRKTLRSIikepfnthNMYTMRER----NEKVEELLARVGLHpsfagrypheFSGGQRQRIGIARA-LTLN 178
Cdd:PTZ00243  1405 --DPFLEASSAEVWAAL--------ELVGLRERvaseSEGIDSRVLEGGSN----------YSVGQRQLMCMARAlLKKG 1464

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557  179 PELIIADEPVS----ALDVSIQAQVINLMEelqeefNLTYLFISHDLSVVRHIsDRVGVMYLGKMMELTGKFELYDNP 252
Cdd:PTZ00243  1465 SGFILMDEATAnidpALDRQIQATVMSAFS------AYTVITIAHRLHTVAQY-DKIIVMDHGAVAEMGSPRELVMNR 1535

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

43-235

2.80e-11

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.44 E-value: 2.80e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  43 LKKGETLGIVGESGCGKSTAGR--------------------TMIRLYKPTEGQILFKgqdisNLSEEKLRkSVRKnIQM 102
Cdd:PRK13409   96 PKEGKVTGILGPNGIGKTTAVKilsgelipnlgdyeeepswdEVLKRFRGTELQNYFK-----KLYNGEIK-VVHK-PQY 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 103 VFQDPfaslnprKTLRSIIKEPFNTHNmytmrERNeKVEELLARVGLHPSFaGRYPHEFSGGQRQRIGIARALTLNPELI 182
Cdd:PRK13409  169 VDLIP-------KVFKGKVRELLKKVD-----ERG-KLDEVVERLGLENIL-DRDISELSGGELQRVAIAAALLRDADFY 234

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 183 IADEPVSALDVSIQAQVINLMEELQEefNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:PRK13409  235 FFDEPTSYLDIRQRLNVARLIRELAE--GKYVLVVEHDLAVLDYLADNVHIAY 285

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

35-241

3.11e-11

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 64.14 E-value: 3.11e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMirlykPTEGQILFKGQD----ISNLSEEKLrkSVRKNIQMvfq 105
Cdd:PRK13545   39 ALNNISFEVPEGEIVGIIGLNGSGKSTlsnliAGVTM-----PNKGTVDIKGSAaliaISSGLNGQL--TGIENIEL--- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 106 dpfaslnprKTLrsiikepfnthnmyTMRERNEKVEELLARVglhPSFA--GRYPHE----FSGGQRQRIGIARALTLNP 179
Cdd:PRK13545  109 ---------KGL--------------MMGLTKEKIKEIIPEI---IEFAdiGKFIYQpvktYSSGMKSRLGFAISVHINP 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 180 ELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:PRK13545  163 DILVIDEALSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKE 223

PLN03211

ABC transporter G-25; Provisional

36-289

3.60e-11

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 64.13 E-value: 3.60e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTagrtmirLYKPTEGQIL---FKGQDISNlsEEKLRKSVRKNIQMVFQDP--FAS 110
Cdd:PLN03211   84 LNGVTGMASPGEILAVLGPSGSGKST-------LLNALAGRIQgnnFTGTILAN--NRKPTKQILKRTGFVTQDDilYPH 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 111 LNPRKTLR--SIIKEPfnthNMYTMRERNEKVEELLARVGL----HPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIA 184
Cdd:PLN03211  155 LTVRETLVfcSLLRLP----KSLTKQEKILVAESVISELGLtkceNTIIGNSFIRGISGGERKRVSIAHEMLINPSLLIL 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 185 DEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGV------MYLGKMMELTGKFELYDN----PLH 254
Cdd:PLN03211  231 DEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVlsegrcLFFGKGSDAMAYFESVGFspsfPMN 310

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2181075557 255 PYTQALLSSVPVTRKRGSVKRERIVLKGELPSPAN 289
Cdd:PLN03211  311 PADFLLDLANGVCQTDGVSEREKPNVKQSLVASYN 345

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

39-225

5.12e-11

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 61.12 E-value: 5.12e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnlseEKLRKSVRKniQMVFQDPFASLNPRKTLR 118
Cdd:PRK13540   20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI-----KKDLCTYQK--QLCFVGHRSGINPYLTLR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 119 SIIKepFNTHNMYTMRERNE-----KVEELLarvglhpsfagRYP-HEFSGGQRQRIGIARALTLNPELIIADEPVSALD 192
Cdd:PRK13540   93 ENCL--YDIHFSPGAVGITElcrlfSLEHLI-----------DYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD 159

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2181075557 193 VSIQAQVINLMEELQEEFNLTYLFISHDLSVVR 225
Cdd:PRK13540  160 ELSLLTIITKIQEHRAKGGAVLLTSHQDLPLNK 192

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

31-226

7.34e-11

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 63.23 E-value: 7.34e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVkAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMI--------RLYKPTEGQILFkgqdisnlseeklrksvrkniqm 102
Cdd:TIGR00954 464 GDV-LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGelwpvyggRLTKPAKGKLFY----------------------- 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 103 VFQDPFASLnprKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHP--------SFAGRYPHEFSGGQRQRIGIARA 174
Cdd:TIGR00954 520 VPQRPYMTL---GTLRDQIIYPDSSEDMKRRGLSDKDLEQILDNVQLTHilereggwSAVQDWMDVLSGGEKQRIAMARL 596

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2181075557 175 LTLNPELIIADEPVSALDVSIQAQvinlMEELQEEFNLTYLFISHDLSVVRH 226
Cdd:TIGR00954 597 FYHKPQFAILDECTSAVSVDVEGY----MYRLCREFGITLFSVSHRKSLWKY 644

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

40-235

8.43e-11

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 62.88 E-value: 8.43e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  40 SFSL------KKGETLGIVGESGCGKSTA------------GR--------TMIRLYKPTEGQILFKgqdisNLSEEKLR 93
Cdd:COG1245    87 GFRLyglpvpKKGKVTGILGPNGIGKSTAlkilsgelkpnlGDydeepswdEVLKRFRGTELQDYFK-----KLANGEIK 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  94 KSVRknIQMVFQDP-FASLNPRKTLRSIikepfnthnmytmRERNeKVEELLARVGLHPSFaGRYPHEFSGGQRQRIGIA 172
Cdd:COG1245   162 VAHK--PQYVDLIPkVFKGTVRELLEKV-------------DERG-KLDELAEKLGLENIL-DRDISELSGGELQRVAIA 224

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 173 RALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:COG1245   225 AALLRDADFYFFDEPSSYLDIYQRLNVARLIRELAEE-GKYVLVVEHDLAILDYLADYVHILY 286

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

39-252

9.84e-11

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 63.04 E-value: 9.84e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvRKNIQMVFQDP--FASlnprkT 116
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDL----RFKITIIPQDPvlFSG-----S 1375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  117 LRSIIkEPFNTHNmytmrerNEKVEELLARVGLHpSFAGRYP----HE-------FSGGQRQRIGIARALTLNPELIIAD 185
Cdd:TIGR00957 1376 LRMNL-DPFSQYS-------DEEVWWALELAHLK-TFVSALPdkldHEcaeggenLSVGQRQLVCLARALLRKTKILVLD 1446

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557  186 EPVSALDVS----IQAQVINLMEelqeefNLTYLFISHDLSVvrhISDRVGVMYLGKmmeltGKFELYDNP 252
Cdd:TIGR00957 1447 EATAAVDLEtdnlIQSTIRTQFE------DCTVLTIAHRLNT---IMDYTRVIVLDK-----GEVAEFGAP 1503

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

21-234

1.64e-10

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 61.95 E-value: 1.64e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  21 IRSGLFqrKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLRKSV---- 96
Cdd:PRK10938    6 ISQGTF--RLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVsdew 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  97 -RKNIQMVFQDPFaslNPRKTLRSIIKEpfNTHNmytmrerNEKVEELLARVGLHPSFAGRYPHeFSGGQRQRIGIARAL 175
Cdd:PRK10938   84 qRNNTDMLSPGED---DTGRTTAEIIQD--EVKD-------PARCEQLAQQFGITALLDRRFKY-LSTGETRKTLLCQAL 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2181075557 176 TLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVM 234
Cdd:PRK10938  151 MSEPDLLILDEPFDGLDVASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVL 208

ABC2_perm_RbbA

NF033858

ribosome-associated ATPase/putative transporter RbbA;

31-187

2.64e-10

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 61.29 E-value: 2.64e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRTMIRlykptEGQILFKGQDISNLSEEK------------LR 93
Cdd:NF033858   12 GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSllsliAGARKIQ-----QGRVEVLGGDMADARHRRavcpriaympqgLG 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  94 K------SVRKNIQmvFqdpFASLnprktlrsiikepFNtHNMytmRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQ 167
Cdd:NF033858   87 KnlyptlSVFENLD--F---FGRL-------------FG-QDA---AERRRRIDELLRATGLAP-FADRPAGKLSGGMKQ 143

                         170       180
                  ....*....|....*....|
gi 2181075557 168 RIGIARALTLNPELIIADEP 187
Cdd:NF033858  144 KLGLCCALIHDPDLLILDEP 163

PRK11147

ABC transporter ATPase component; Reviewed

31-249

2.72e-10

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 61.12 E-value: 2.72e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKgQD--ISNLSEEKLR--------------- 93
Cdd:PRK11147   14 SDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYE-QDliVARLQQDPPRnvegtvydfvaegie 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  94 ------KSVRKNIQMVFQDPFAS-LNPRKTLRSIIkepfNTHNMYTMRERnekVEELLARVGLHPSFAgryPHEFSGGQR 166
Cdd:PRK11147   93 eqaeylKRYHDISHLVETDPSEKnLNELAKLQEQL----DHHNLWQLENR---INEVLAQLGLDPDAA---LSSLSGGWL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 167 QRIGIARALTLNPELIIADEPVSALDVsiqaQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKF 246
Cdd:PRK11147  163 RKAALGRALVSNPDVLLLDEPTNHLDI----ETIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLVSYPGNY 238


                  ...
gi 2181075557 247 ELY 249
Cdd:PRK11147  239 DQY 241

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

1-277

2.92e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 61.57 E-value: 2.92e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557    1 MTAANQETILELRDVKKYFPIRSGlfqrkvgdvKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK 80
Cdd:TIGR01257 1929 ISGGNKTDILRLNELTKVYSGTSS---------PAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVA 1999

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   81 GQDI-SNLSEeklrksVRKNiqMVFQDPFASLNPRKTLRSiikepfntHNMYTMRERNEKVEEL-------LARVGLhPS 152
Cdd:TIGR01257 2000 GKSIlTNISD------VHQN--MGYCPQFDAIDDLLTGRE--------HLYLYARLRGVPAEEIekvanwsIQSLGL-SL 2062

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  153 FAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLfISHDLSVVRHISDRVG 232
Cdd:TIGR01257 2063 YADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVL-TSHSMEECEALCTRLA 2141

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557  233 VMY------LGKMMELTGKF---------------ELYDNpLHPYTQALLSSVPvtrkrGSVKRER 277
Cdd:TIGR01257 2142 IMVkgafqcLGTIQHLKSKFgdgyivtmkikspkdDLLPD-LNPVEQFFQGNFP-----GSVQRER 2201

PRK10522

multidrug transporter membrane component/ATP-binding component; Provisional

10-244

5.30e-10

multidrug transporter membrane component/ATP-binding component; Provisional

Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 60.37 E-value: 5.30e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSglFqrkvgdvkAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlse 89
Cdd:PRK10522  323 LELRNVTFAYQDNG--F--------SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVT---- 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 EKLRKSVRKNIQMVFQD--PFAS-LNPRKTlrsiIKEPfnthnmytmrernEKVEELLARVGLHPSFA---GRYPH-EFS 162
Cdd:PRK10522  389 AEQPEDYRKLFSAVFTDfhLFDQlLGPEGK----PANP-------------ALVEKWLERLKMAHKLEledGRISNlKLS 451

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 163 GGQRQRIGIARALTLNPELIIADEpvSALDVSIQAQVI---NLMEELQEEfNLTYLFISHDLSVVRHiSDRVGVMYLGKM 239
Cdd:PRK10522  452 KGQKKRLALLLALAEERDILLLDE--WAADQDPHFRREfyqVLLPLLQEM-GKTIFAISHDDHYFIH-ADRLLEMRNGQL 527


                  ....*
gi 2181075557 240 MELTG 244
Cdd:PRK10522  528 SELTG 532

40850658_otr

NF000106

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

10-245

5.32e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 59.75 E-value: 5.32e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTaGRTMIRLYKPTEGQILFKGQD-ISNls 88
Cdd:NF000106   14 VEVRGLVKHF-----------GEVKAVDGVDLDVREGTVLGVLGP*GAA**R-GALPAHV*GPDAGRRPWRF*TwCAN-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 eeklRKSVRKNIqmvfqdpfaslNPRKTLRSIIKEPFN-THNMYTM--------RERNEKVEELLARVGLHPSfAGRYPH 159
Cdd:NF000106   80 ----RRALRRTI-----------G*HRPVR*GRRESFSgRENLYMIgr*ldlsrKDARARADELLERFSLTEA-AGRAAA 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLF---------ISHDLSVVrhisDR 230
Cdd:NF000106  144 KYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTtqymeeaeqLAHELTVI----DR 219

                         250
                  ....*....|....*
gi 2181075557 231 VGVMYLGKMMELTGK 245
Cdd:NF000106  220 GRVIADGKVDELKTK 234

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

11-234

1.19e-09

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 59.15 E-value: 1.19e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  11 ELRDVKKYFPirsglfqRKVGDV----KAVDG------VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFK 80
Cdd:PRK11288  241 EIGDIYGYRP-------RPLGEVrlrlDGLKGpglrepISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLD 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  81 GQDISNLSEeklRKSVRKNIQMVFQDpfaslnpRKT-----LRSIiKEPFNT----HNMYTMRERNEKVEELLARVGLHp 151
Cdd:PRK11288  314 GKPIDIRSP---RDAIRAGIMLCPED-------RKAegiipVHSV-ADNINIsarrHHLRAGCLINNRWEAENADRFIR- 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 152 SFAGRYPH------EFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVR 225
Cdd:PRK11288  382 SLNIKTPSreqlimNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQ-GVAVLFVSSDLPEVL 460


                  ....*....
gi 2181075557 226 HISDRVGVM 234
Cdd:PRK11288  461 GVADRIVVM 469

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

35-241

1.30e-09

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 57.90 E-value: 1.30e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGqDISNLSEEklrksvrkniqmvfqdpfASLNPR 114
Cdd:PRK13546   39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-EVSVIAIS------------------AGLSGQ 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KTLRSIIKepfntHNMYTMRERNEKVEELLARVgLHPSFAGRYPHE----FSGGQRQRIGIARALTLNPELIIADEPVSA 190
Cdd:PRK13546  100 LTGIENIE-----FKMLCMGFKRKEIKAMTPKI-IEFSELGEFIYQpvkkYSSGMRAKLGFSINITVNPDILVIDEALSV 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 191 LDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVGVMYLGKMME 241
Cdd:PRK13546  174 GDQTFAQKCLDKIYEFKEQ-NKTIFFVSHNLGQVRQFCTKIAWIEGGKLKD 223

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

6-231

1.86e-09

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 58.79 E-value: 1.86e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   6 QETILELRDVKKYFPIrsglfQRKVgdvkaVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILF-KGQDI 84
Cdd:TIGR03719   1 AQYIYTMNRVSKVVPP-----KKEI-----LKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPqPGIKV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  85 SNLSEE-KL--RKSVRKNIQMVFQDPFASLNPRKTLRSIIKEPfnTHNMYTMRERNEKVEELLARVGLH--------PSF 153
Cdd:TIGR03719  71 GYLPQEpQLdpTKTVRENVEEGVAEIKDALDRFNEISAKYAEP--DADFDKLAAEQAELQEIIDAADAWdldsqleiAMD 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 154 AGRYP------HEFSGGQRQRIGIARALTLNPELIIADEPVSALDvsiqAQVINLMEELQEEFNLTYLFISHDlsvvRHI 227
Cdd:TIGR03719 149 ALRCPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD----AESVAWLERHLQEYPGTVVAVTHD----RYF 220


                  ....
gi 2181075557 228 SDRV 231
Cdd:TIGR03719 221 LDNV 224

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

43-235

2.00e-09

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 56.04 E-value: 2.00e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  43 LKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISnlseeklrksvrkniqmvfqdpfasLNPRKTlrsiik 122
Cdd:cd03222    22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-------------------------YKPQYI------ 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 123 epfnthnmytmrernekveellarvglhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINL 202
Cdd:cd03222    71 -------------------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARA 113

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2181075557 203 MEELQEEFNLTYLFISHDLSVVRHISDRVGVMY 235
Cdd:cd03222   114 IRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFE 146

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

7-239

6.07e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 57.05 E-value: 6.07e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVkkyfpirSGLFQRKVGDVkavdgvSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISN 86
Cdd:PRK10982  248 EVILEVRNL-------TSLRQPSIRDV------SFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINN 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  87 -------------LSEEKLRKSVRKNIQMVFQDPFASLNPRKTlrsiikePFNTHNMYTMRERNEKV-EELLARVGLHPS 152
Cdd:PRK10982  315 hnaneainhgfalVTEERRSTGIYAYLDIGFNSLISNIRNYKN-------KVGLLDNSRMKSDTQWViDSMRVKTPGHRT 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 153 FAGryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTYLFISHDLSVVRHISDRVG 232
Cdd:PRK10982  388 QIG----SLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKK-DKGIIIISSEMPELLGITDRIL 462


                  ....*..
gi 2181075557 233 VMYLGKM 239
Cdd:PRK10982  463 VMSNGLV 469

PRK11147

ABC transporter ATPase component; Reviewed

30-220

6.42e-09

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 56.88 E-value: 6.42e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  30 VGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnlseeklrkSVRKNIQMVFQDPF- 108
Cdd:PRK11147  329 IDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI-----------------HCGTKLEVAYFDQHr 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 109 ASLNPRKTLRSIIKEPFNThNMYTMRERNekVEELLARVGLHPSFAgRYP-HEFSGGQRQRIGIARaLTLNP-ELIIADE 186
Cdd:PRK11147  392 AELDPEKTVMDNLAEGKQE-VMVNGRPRH--VLGYLQDFLFHPKRA-MTPvKALSGGERNRLLLAR-LFLKPsNLLILDE 466

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2181075557 187 PVSALDVsiqaQVINLMEELQEEFNLTYLFISHD 220
Cdd:PRK11147  467 PTNDLDV----ETLELLEELLDSYQGTVLLVSHD 496

rim_protein

TIGR01257

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

35-311

6.47e-09

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 57.33 E-value: 6.47e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   35 AVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDI-SNLSeeklrkSVRKNIQMVFQDP--FASL 111
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLD------AVRQSLGMCPQHNilFHHL 1018

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  112 NprktlrsiIKEPFNTHNMYTMRERNE---KVEELLARVGLHPSfAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPV 188
Cdd:TIGR01257 1019 T--------VAEHILFYAQLKGRSWEEaqlEMEAMLEDTGLHHK-RNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPT 1089

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  189 SALDVSIQAQVINLMeeLQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMeLTGKFELYDNPLHpyTQALLSSVpvtR 268
Cdd:TIGR01257 1090 SGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLY-CSGTPLFLKNCFG--TGFYLTLV---R 1161

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2181075557  269 KRGSVKRERivlKGELPSPANPPKGcvFHTRCPV-AKPICKEQI 311
Cdd:TIGR01257 1162 KMKNIQSQR---GGCEGTCSCTSKG--FSTRCPArVDEITPEQV 1200

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

45-231

6.94e-09

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.92 E-value: 6.94e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   45 KGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFkgqdisnlseeklrksvrkniqmvfqdpfasLNPRKTLRSiikep 124
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-------------------------------IDGEDILEE----- 44

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  125 fnthnmytmrernekveellARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVI---- 200
Cdd:smart00382  45 --------------------VLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLllee 104

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 2181075557  201 -NLMEELQEEFNLTYLFISHDLSV-----VRHISDRV 231
Cdd:smart00382 105 lRLLLLLKSEKNLTVILTTNDEKDlgpalLRRRFDRR 141

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

9-231

9.86e-09

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 56.48 E-value: 9.86e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   9 ILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnls 88
Cdd:TIGR03719 322 VIEAENLTKAF-----------GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTI----------- 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  89 eeklrkSVRKNIQMVFQDPF-ASLNPRKTLRSIIKEPFNTHNM--YTMRER------NEKVEELLARVGlhpsfagryph 159
Cdd:TIGR03719 380 ------EIGETVKLAYVDQSrDALDPNKTVWEEISGGLDIIKLgkREIPSRayvgrfNFKGSDQQKKVG----------- 442

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 160 EFSGGQRQRIGIARALTLNPELIIADEPVSALDV-SIQAqvinlMEELQEEFNLTYLFISHDlsvvRHISDRV 231
Cdd:TIGR03719 443 QLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVeTLRA-----LEEALLNFAGCAVVISHD----RWFLDRI 506

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

36-240

1.20e-08

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 55.22 E-value: 1.20e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMI-RLYKPTE-------GQILFKGQDISNLSEEKL---RKSVRKNIQMVF 104
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAgDLTGGGAprgarvtGDVTLNGEPLAAIDAPRLarlRAVLPQAAQPAF 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 105 qdPFASlnprKTLRSIIKEPFNTHNMYTMRERNEKVEELLARVGLHPsFAGRYPHEFSGGQRQRIGIARAL--------- 175
Cdd:PRK13547   97 --AFSA----REIVLLGRYPHARRAGALTHRDGEIAWQALALAGATA-LVGRDVTTLSGGELARVQFARVLaqlwpphda 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2181075557 176 TLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMM 240
Cdd:PRK13547  170 AQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIV 234

PLN03130

ABC transporter C family member; Provisional

162-247

3.48e-08

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 55.13 E-value: 3.48e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVIN--LMEELQeefNLTYLFISHDLSVVRHIsDRVGVMYLGKM 239
Cdd:PLN03130   742 SGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDkcIKDELR---GKTRVLVTNQLHFLSQV-DRIILVHEGMI 817


                   ....*...
gi 2181075557  240 MElTGKFE 247
Cdd:PLN03130   818 KE-EGTYE 824

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

10-106

4.52e-08

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 54.42 E-value: 4.52e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSG--LFQrkVGDVkavdgvSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDIsnl 87
Cdd:COG4615   328 LELRGVTYRYPGEDGdeGFT--LGPI------DLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPV--- 396

                          90
                  ....*....|....*....
gi 2181075557  88 sEEKLRKSVRKNIQMVFQD 106
Cdd:COG4615   397 -TADNREAYRQLFSAVFSD 414

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

39-199

5.49e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 54.53 E-value: 5.49e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdISNLSEEK--LRKSVRKNIQM-VFQDPFaslnprk 115
Cdd:TIGR01271  445 ISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-ISFSPQTSwiMPGTIKDNIIFgLSYDEY------- 516

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  116 TLRSIIKEPFNTHNMYTMRERNEKVeelLARVGLhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSI 195
Cdd:TIGR01271  517 RYTSVIKACQLEEDIALFPEKDKTV---LGEGGI----------TLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVT 583


                   ....
gi 2181075557  196 QAQV 199
Cdd:TIGR01271  584 EKEI 587

GguA

NF040905

sugar ABC transporter ATP-binding protein;

7-246

6.48e-08

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 6.48e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   7 ETILELRDVKKYFPIRSglfQRKVgdvkaVDGVSFSLKKGETLGIVGESGcgkstAGRTMI------RLY-KPTEGQILF 79
Cdd:NF040905  255 EVVFEVKNWTVYHPLHP---ERKV-----VDDVSLNVRRGEIVGIAGLMG-----AGRTELamsvfgRSYgRNISGTVFK 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  80 KGQ--DISNLSE----------EKlRK--------SVRKNIQMvfqdpfASLnPRKTLRSIIkepfNTHNMYTMRER--- 136
Cdd:NF040905  322 DGKevDVSTVSDaidaglayvtED-RKgyglnlidDIKRNITL------ANL-GKVSRRGVI----DENEEIKVAEEyrk 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 137 --NEKVEELLARVGlhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEfNLTY 214
Cdd:NF040905  390 kmNIKTPSVFQKVG-----------NLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGV 457

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2181075557 215 LFISHDLSVVRHISDRVGVMYLGKmmeLTGKF 246
Cdd:NF040905  458 IVISSELPELLGMCDRIYVMNEGR---ITGEL 486

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

36-239

1.56e-07

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 51.11 E-value: 1.56e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKST---AGRTMIRLYKPTEGQILFKGQDIsnlseeklrksvrkniqmvfqDPFASLN 112
Cdd:cd03233    23 LKDFSGVVKPGEMVLVLGRPGSGCSTllkALANRTEGNVSVEGDIHYNGIPY---------------------KEFAEKY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 PRktlrSIIKEPFNTHNMYTMrerneKVEELLarvglhpSFAGR-----YPHEFSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:cd03233    82 PG----EIIYVSEEDVHFPTL-----TVRETL-------DFALRckgneFVRGISGGERKRVSIAEALVSRASVLCWDNS 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2181075557 188 VSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSV-VRHISDRVGVMYLGKM 239
Cdd:cd03233   146 TRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDeIYDLFDKVLVLYEGRQ 198

ABCC_SUR2

cd03288

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...

43-196

1.66e-07

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 51.45 E-value: 1.66e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  43 LKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQDISNLSEEKLrksvRKNIQMVFQDPFA-------SLNP-R 114
Cdd:cd03288    44 IKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTL----RSRLSIILQDPILfsgsirfNLDPeC 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 115 KTLRSIIKEPFNTHNMYTMrernekVEELLARVGLHPSFAGrypHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVS 194
Cdd:cd03288   120 KCTDDRLWEALEIAQLKNM------VKSLPGGLDAVVTEGG---ENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMA 190


                  ..
gi 2181075557 195 IQ 196
Cdd:cd03288   191 TE 192

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

39-199

3.16e-07

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 51.01 E-value: 3.16e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKGQdISNLSEEK--LRKSVRKNIQmvfqdpFASLNPRKT 116
Cdd:cd03291    56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-ISFSSQFSwiMPGTIKENII------FGVSYDEYR 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 117 LRSIIKEPFNTHNMYTMRERNEKVeelLARVGLhpsfagryphEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQ 196
Cdd:cd03291   129 YKSVVKACQLEEDITKFPEKDNTV---LGEGGI----------TLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTE 195


                  ...
gi 2181075557 197 AQV 199
Cdd:cd03291   196 KEI 198

PRK10636

putative ABC transporter ATP-binding protein; Provisional

36-246

4.77e-07

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 51.32 E-value: 4.77e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTagrtMIRLYK------------PTEGQILFKGQDISNLSEEKLRKSV---RKNI 100
Cdd:PRK10636   17 LDNATATINPGQKVGLVGKNGCGKST----LLALLKneisadggsytfPGNWQLAWVNQETPALPQPALEYVIdgdREYR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 101 QMvfQDPFASLNPRKTLRSI--IKEPFNTHNMYTMRERnekVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLN 178
Cdd:PRK10636   93 QL--EAQLHDANERNDGHAIatIHGKLDAIDAWTIRSR---AASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICR 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2181075557 179 PELIIADEPVSALDVSiqaQVINLmEELQEEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKF 246
Cdd:PRK10636  168 SDLLLLDEPTNHLDLD---AVIWL-EKWLKSYQGTLILISHDRDFLDPIVDKIIHIEQQSLFEYTGNY 231

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

36-200

6.38e-07

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 49.85 E-value: 6.38e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  36 VDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKpTEGQILFKGQDISNLSEEKLRKSVRKNIQMV--FQDPFaslnp 113
Cdd:cd03289    20 LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKWRKAFGVIPQKVfiFSGTF----- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 114 RKTLrsiikEPFNTHNmytmrerNEKVEELLARVGLHpSFAGRYPHE-----------FSGGQRQRIGIARALTLNPELI 182
Cdd:cd03289    94 RKNL-----DPYGKWS-------DEEIWKVAEEVGLK-SVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKIL 160

                         170
                  ....*....|....*...
gi 2181075557 183 IADEPVSALDvSIQAQVI 200
Cdd:cd03289   161 LLDEPSAHLD-PITYQVI 177

PLN03073

ABC transporter F family; Provisional

21-193

8.32e-07

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 50.63 E-value: 8.32e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  21 IRSGLFQRKVGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIrLYK----PTEGQIL-----FKGQDISNL---- 87
Cdd:PLN03073  178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMA-MHAidgiPKNCQILhveqeVVGDDTTALqcvl 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 -SEEKLRKSVRKNIQMVFQD-----PFASLNPRKTLRSIIKEPFNTHNMYTMRERNEKVE---------ELLARVGLHPS 152
Cdd:PLN03073  257 nTDIERTQLLEEEAQLVAQQrelefETETGKGKGANKDGVDKDAVSQRLEEIYKRLELIDaytaearaaSILAGLSFTPE 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2181075557 153 FAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV 193
Cdd:PLN03073  337 MQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

39-219

1.06e-06

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 50.29 E-value: 1.06e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKpTEGQILFKGQDISNLSEEKLRKSVRKNIQMVFqdpfaslnprkTLR 118
Cdd:TIGR01271 1238 LSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTWRKAFGVIPQKVF-----------IFS 1305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  119 SIIKEPFNTHNMYTMRERNEKVEEllarVGLHpSFAGRYPHE-----------FSGGQRQRIGIARALTLNPELIIADEP 187
Cdd:TIGR01271 1306 GTFRKNLDPYEQWSDEEIWKVAEE----VGLK-SVIEQFPDKldfvlvdggyvLSNGHKQLMCLARSILSKAKILLLDEP 1380

                          170       180       190
                   ....*....|....*....|....*....|...
gi 2181075557  188 VSALDvSIQAQVINlmEELQEEF-NLTYLFISH 219
Cdd:TIGR01271 1381 SAHLD-PVTLQIIR--KTLKQSFsNCTVILSEH 1410

PLN03232

ABC transporter C family member; Provisional

162-207

1.58e-06

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 49.97 E-value: 1.58e-06

                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2181075557  162 SGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVIN--LMEELQ 207
Cdd:PLN03232   742 SGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDscMKDELK 789

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

8-231

6.42e-06

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 47.81 E-value: 6.42e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   8 TILELRDVKKYFpirsglfqrkvGDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnl 87
Cdd:PRK11819  323 KVIEAENLSKSF-----------GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTI---------- 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  88 seeKLRKSVrkniQMVFQDPF-ASLNPRKTLRSIIKEPFNTHNM--YTMRER------NEKVEELLARVGlhpsfagryp 158
Cdd:PRK11819  382 ---KIGETV----KLAYVDQSrDALDPNKTVWEEISGGLDIIKVgnREIPSRayvgrfNFKGGDQQKKVG---------- 444

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2181075557 159 hEFSGGQRQRIGIARALTLNPELIIADEPVSALDV-SIQAqvinlMEELQEEFNLTYLFISHDlsvvRHISDRV 231
Cdd:PRK11819  445 -VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVeTLRA-----LEEALLEFPGCAVVISHD----RWFLDRI 508

PRK10636

putative ABC transporter ATP-binding protein; Provisional

31-249

1.62e-05

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 46.32 E-value: 1.62e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  31 GDVKAVDGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQI-LFKGQDISNLSEEKLrKSVRkniqmvfqdpfA 109
Cdd:PRK10636  323 GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIgLAKGIKLGYFAQHQL-EFLR-----------A 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 110 SLNPRKTLRSIIKepfnthnmytmRERNEKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVS 189
Cdd:PRK10636  391 DESPLQHLARLAP-----------QELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTN 459

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557 190 ALDVSI-QAqvinLMEELQeEFNLTYLFISHDLSVVRHISDRVGVMYLGKMMELTGKFELY 249
Cdd:PRK10636  460 HLDLDMrQA----LTEALI-DFEGALVVVSHDRHLLRSTTDDLYLVHDGKVEPFDGDLEDY 515

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

33-231

1.79e-05

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 44.62 E-value: 1.79e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  33 VKAVDGVSFSLKKGETLGIVGESGCGKSTagrtmirlykptegqILFKGqdisnlSEEKLRKSVRKNIQMVFQDPFASLn 112
Cdd:cd03238     8 VHNLQNLDVSIPLNVLVVVTGVSGSGKST---------------LVNEG------LYASGKARLISFLPKFSRNKLIFI- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 113 prKTLRSIIKepfnthnmytmrernekveellarVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPE--LIIADEPVSA 190
Cdd:cd03238    66 --DQLQFLID------------------------VGLGYLTLGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTG 119

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2181075557 191 LDVSIQAQVINLMEELQEEFNlTYLFISHDLSVVRHiSDRV 231
Cdd:cd03238   120 LHQQDINQLLEVIKGLIDLGN-TVILIEHNLDVLSS-ADWI 158

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

139-219

2.84e-05

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 45.39 E-value: 2.84e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 139 KVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFIS 218
Cdd:PRK10938  380 LAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVS 459


                  .
gi 2181075557 219 H 219
Cdd:PRK10938  460 H 460

PRK15064

ABC transporter ATP-binding protein; Provisional

10-249

3.43e-05

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 45.27 E-value: 3.43e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  10 LELRDVKKYFPIRSgLFQrkvgdvkavdGVSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQIlfkgqdisnlse 89
Cdd:PRK15064  320 LEVENLTKGFDNGP-LFK----------NLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV------------ 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  90 eklRKSVRKNIQMVFQDPFASLNPRKTLrsiikepfnthnMYTMRE-RNEKVEELLARvglhpSFAGRY----------P 158
Cdd:PRK15064  377 ---KWSENANIGYYAQDHAYDFENDLTL------------FDWMSQwRQEGDDEQAVR-----GTLGRLlfsqddikksV 436

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 159 HEFSGGQRQRIGIARALTLNPELIIADEPVSALDV-SIQAQVINLmeelqEEFNLTYLFISHDLSVVRHISDRVGVMYLG 237
Cdd:PRK15064  437 KVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMeSIESLNMAL-----EKYEGTLIFVSHDREFVSSLATRIIEITPD 511

                         250
                  ....*....|..
gi 2181075557 238 KMMELTGKFELY 249
Cdd:PRK15064  512 GVVDFSGTYEEY 523

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

27-238

5.16e-04

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 42.02 E-value: 5.16e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   27 QRKVGDVKAVDGVsfsLKKGETLGIVGESGCGKST-----AGRTmIRLYKPTEGQILFKGqdisnLSEEKLRKSVRKNIQ 101
Cdd:TIGR00956   71 TKTFDILKPMDGL---IKPGELTVVLGRPGSGCSTllktiASNT-DGFHIGVEGVITYDG-----ITPEEIKKHYRGDVV 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  102 MVFQDP--FASLNPRKTLRSII--KEPFNTHNMYTMRERNEKVEELLARV-GLHPSFAGRYPHEF----SGGQRQRIGIA 172
Cdd:TIGR00956  142 YNAETDvhFPHLTVGETLDFAArcKTPQNRPDGVSREEYAKHIADVYMATyGLSHTRNTKVGNDFvrgvSGGERKRVSIA 221

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2181075557  173 RALTLNPELIIADEPVSALDVSIQAQVINLMEELQEEFNLTYLFISHDLSV-VRHISDRVGVMYLGK 238
Cdd:TIGR00956  222 EASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQdAYELFDKVIVLYEGY 288

PTZ00243

ABC transporter; Provisional

39-200

8.55e-04

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 41.30 E-value: 8.55e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   39 VSFSLKKGETLGIVGESGCGKSTAGRTMIRLYKPTEGQILFKgQDISNLSEEK--LRKSVRKNIqmVFQDPFASLNPRKT 116
Cdd:PTZ00243   679 VSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAE-RSIAYVPQQAwiMNATVRGNI--LFFDEEDAARLADA 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557  117 LRsiikepfnthnmytmrernekVEELLARV-----GLHPSFaGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSAL 191
Cdd:PTZ00243   756 VR---------------------VSQLEADLaqlggGLETEI-GEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSAL 813


                   ....*....
gi 2181075557  192 DVSIQAQVI 200
Cdd:PTZ00243   814 DAHVGERVV 822

PLN03073

ABC transporter F family; Provisional

138-253

1.84e-03

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 39.84 E-value: 1.84e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557 138 EKVEELLARVGLHPSFAGRYPHEFSGGQRQRIGIARALTLNPELIIADEPVSALDV-SIQAQVINLMeelqeEFNLTYLF 216
Cdd:PLN03073  605 QKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLdAVEALIQGLV-----LFQGGVLM 679

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2181075557 217 ISHDLSVVRHISDRVGVMYLGKMMELTGKFELYDNPL 253
Cdd:PLN03073  680 VSHDEHLISGSVDELWVVSEGKVTPFHGTFHDYKKTL 716

PLN03140

ABC transporter G family member; Provisional

14-200

1.89e-03

ABC transporter G family member; Provisional

Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 40.21 E-value: 1.89e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   14 DVKKYFPIRSGLFQRKVGD--VKAVDGVSFSLKKGETLGIVGESGCGKST-----AGRTM-------IRLYKPTEGQILF 79
Cdd:PLN03140   872 DVNYFVDMPAEMKEQGVTEdrLQLLREVTGAFRPGVLTALMGVSGAGKTTlmdvlAGRKTggyiegdIRISGFPKKQETF 951

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2181075557   80 KgqDISNLSEE--------------------KLRKSVRKNIQMVFQDPFASLNPRKTLRSIIkepfnthnmytmrernek 139
Cdd:PLN03140   952 A--RISGYCEQndihspqvtvresliysaflRLPKEVSKEEKMMFVDEVMELVELDNLKDAI------------------ 1011

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2181075557  140 veellarVGLhPSFAGrypheFSGGQRQRIGIARALTLNPELIIADEPVSALDVSIQAQVI 200
Cdd:PLN03140  1012 -------VGL-PGVTG-----LSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVM 1059

PRK15064

ABC transporter ATP-binding protein; Provisional

168-229

2.65e-03

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 39.49 E-value: 2.65e-03

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2181075557 168 RIGIARALTLNPELIIADEPVSALDVSiqaqVINLMEELQEEFNLTYLFISHDL----SVVRHISD 229
Cdd:PRK15064  163 RVLLAQALFSNPDILLLDEPTNNLDIN----TIRWLEDVLNERNSTMIIISHDRhflnSVCTHMAD 224

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01