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Concise Results
Standard Results
Full Results
Na+/H+ antiporter NhaA [Catellatospora methionotrophica]
Protein Classification
Na+/H+ antiporter NhaA ( domain architecture ID 10006841 )
Na+/H+ antiporter NhaA extrudes sodium in exchange for external protons
List of domain hits
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
34-413
1.41e-148
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 426.81
E-value: 1.41e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFLR T E QI GG LV LL G A TA LALI I ANSPL SDA Y QR L SAYTF G PQ -- SLHLDLS VAQ W AQ DGL LTV FF VVA GLE L KREL VI G 111
Cdd:COG3004 3 RFLR S E AA GG IL LL L A AV LALI W ANSPL AES Y EA L LHTPL G LG ig SLHLDLS LLH W IN DGL MAI FF FLV GLE I KREL LV G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R SPR Q AALPI AG A I GGMVVPAL LCFLIAF G A P GGSDA WA V P V ATDIAFAL A VLA ICARDL P P SLRVFLL S LAIVDDLG 191
Cdd:COG3004 83 EL S SPR K AALPI IA A L GGMVVPAL IYLAFNA G T P EAARG WA I P M ATDIAFAL G VLA LLGSRV P A SLRVFLL A LAIVDDLG 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AIL L IAL VF T AHVAF L P LL G AAA V L VVY ALL QQFRF R GW W L YLLLG LAA W AL V HA SGVHAT I AGV AIG L LTRVKHDP G -- 269
Cdd:COG3004 163 AIL V IAL FY T SGLSL L A LL L AAA A L ALL ALL NRRGV R SL W P YLLLG VVL W YA V LK SGVHAT L AGV LLA L TIPARPRV G ge 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 270 - E H ESP A E A LEH RIQ P IS A GICV PLFAF FS AG IAI S AGA L G A i F T DRAS LG VLI GLV V GK TV G VLLGAAV AV RAK LA E LP 348
Cdd:COG3004 243 e E A ESP L E R LEH ALH P WV A FLIL PLFAF AN AG VSL S GLS L A A - L T SPVT LG IAL GLV L GK PL G IFGFSWL AV KLG LA R LP 321
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2197168264 349 EALD WR D L FA V AVVT G C GFT V SL L IAELAF DYG E QQARV K GAV LLGSL I A SL L AAG LLR RQV R VR 413
Cdd:COG3004 322 AGVS WR Q L YG V GLLA G I GFT M SL F IAELAF PDP E LLDAA K LGI LLGSL L A AV L GYL LLR LRL R RK 386
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
34-413
1.41e-148
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 426.81
E-value: 1.41e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFLR T E QI GG LV LL G A TA LALI I ANSPL SDA Y QR L SAYTF G PQ -- SLHLDLS VAQ W AQ DGL LTV FF VVA GLE L KREL VI G 111
Cdd:COG3004 3 RFLR S E AA GG IL LL L A AV LALI W ANSPL AES Y EA L LHTPL G LG ig SLHLDLS LLH W IN DGL MAI FF FLV GLE I KREL LV G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R SPR Q AALPI AG A I GGMVVPAL LCFLIAF G A P GGSDA WA V P V ATDIAFAL A VLA ICARDL P P SLRVFLL S LAIVDDLG 191
Cdd:COG3004 83 EL S SPR K AALPI IA A L GGMVVPAL IYLAFNA G T P EAARG WA I P M ATDIAFAL G VLA LLGSRV P A SLRVFLL A LAIVDDLG 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AIL L IAL VF T AHVAF L P LL G AAA V L VVY ALL QQFRF R GW W L YLLLG LAA W AL V HA SGVHAT I AGV AIG L LTRVKHDP G -- 269
Cdd:COG3004 163 AIL V IAL FY T SGLSL L A LL L AAA A L ALL ALL NRRGV R SL W P YLLLG VVL W YA V LK SGVHAT L AGV LLA L TIPARPRV G ge 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 270 - E H ESP A E A LEH RIQ P IS A GICV PLFAF FS AG IAI S AGA L G A i F T DRAS LG VLI GLV V GK TV G VLLGAAV AV RAK LA E LP 348
Cdd:COG3004 243 e E A ESP L E R LEH ALH P WV A FLIL PLFAF AN AG VSL S GLS L A A - L T SPVT LG IAL GLV L GK PL G IFGFSWL AV KLG LA R LP 321
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2197168264 349 EALD WR D L FA V AVVT G C GFT V SL L IAELAF DYG E QQARV K GAV LLGSL I A SL L AAG LLR RQV R VR 413
Cdd:COG3004 322 AGVS WR Q L YG V GLLA G I GFT M SL F IAELAF PDP E LLDAA K LGI LLGSL L A AV L GYL LLR LRL R RK 386
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
34-405
1.73e-146
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 421.04
E-value: 1.73e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFLR T E QI GG LV LL G A TA LALI I ANSPL S D A Y QR L SAYTF G PQ -- S L H L D LS VAQ W AQ DGL LTV FF V V A GLE L KREL VI G 111
Cdd:pfam06965 2 RFLR S E AA GG IL LL A A AV LALI W ANSPL A D S Y EA L WHTPL G VG fg G L S L S LS LHH W IN DGL MAI FF F V V GLE I KREL LV G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R SPR Q AALP IAG A I GGMVVPAL LCFLIAF G A PG GS d A WA V P V ATDIAFAL A VLA ICARDL P P SLRVFLL S LAIVDDLG 191
Cdd:pfam06965 82 EL S SPR K AALP VIA A L GGMVVPAL IYLAFNA G G PG AR - G WA I P M ATDIAFAL G VLA LLGKRV P A SLRVFLL A LAIVDDLG 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AIL L IAL VF T AHVAF L P LL G AAA V L V V YA LL QQFRF R GW W L YLLLG LAA W AL V HA SGVHATIAGV AIG LL TRVKHDPG E H 271
Cdd:pfam06965 161 AIL V IAL FY T SGLSL L A LL A AAA I L A V LL LL NRLGV R RL W P YLLLG VVL W VA V LK SGVHATIAGV LLA LL IPARPPAR E S 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 272 --- E SP A E A LEH RIQ P IS A GICV PLFA FFS AG IAI S AGA LGA IF T DRAS LG VLI GLV V GK TV G VLLGAAV AV RAK LA E LP 348
Cdd:pfam06965 241 rea I SP L E R LEH ALH P WV A FLIL PLFA LAN AG VSL S GSG LGA LL T SPVT LG IAL GLV L GK PL G IFGFSWL AV KLG LA R LP 320
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2197168264 349 E ALD WR D L FA V AVVT G C GFT V SL L IAELAFD YG - E QQARV K GAV LLGSL I A SL L AAGL 405
Cdd:pfam06965 321 E GVT WR Q L LG V GLLA G I GFT M SL F IAELAFD DE l E LLDEA K LGI LLGSL L A AV L GYLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
34-408
1.30e-105
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 317.21
E-value: 1.30e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFL RT E QI GG LV L LG A T ALA L I I ANSPLS DA Y QR - L SAY - TFGPQSLHLDL S VAQ W AQ DGL LT VFF VVA GLE L KREL VI G 111
Cdd:PRK09560 7 RFL KS E AA GG IL L MA A A ALA M I V ANSPLS EG Y FS f L HTP v AIQIGAFSIGK S LLH W IN DGL MA VFF LLV GLE I KREL LE G 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 E L R S PR Q AA LP IAG A I GGMVVPAL LCFLIAFGA P GGSDA WA V P V ATDIAFAL A VLA ICARDL P P SL R VFLL S LAI V DDLG 191
Cdd:PRK09560 87 Q L S S WQ Q RI LP AIA A V GGMVVPAL IYAAFNYNN P ETLRG WA I P A ATDIAFAL G VLA LLGKRV P V SL K VFLL A LAI I DDLG 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AI LL IAL VF T AHVAFLP L LG AA AVLV V YA LL QQFRFRGWWL YL LL G LAA W AL V HA SGVHAT I AGV AIGLLTRV K HDP G EH 271
Cdd:PRK09560 167 AI VI IAL FY T SDLSLPA L AL AA IAIA V LF LL NRLGVTKLTP YL IV G AIL W FA V LK SGVHAT L AGV VLAFCIPL K GKK G DE 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 272 ESP AEA LEH RIQ P IS A GICV PLFAF FS AG IAI s AG ALGAIF T DRAS LG VLI GL VV GK T VGV LLGAAV AV RAK LA E LPE AL 351
Cdd:PRK09560 247 ESP LHH LEH ALH P WV A FAIL PLFAF AN AG VSL - AG ISLSSL T SPVP LG IAL GL FL GK Q VGV FGFSWL AV KLG LA K LPE GA 325
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2197168264 352 D W RDLFA V A V VT G C GFT V SL L I AE LAF DYG E Q - QARVKGAV LLGSL IASL L AAG LLR R 408
Cdd:PRK09560 326 N W KQIYG V S V LC G I GFT M SL F I GS LAF GAS E E l LTEARLGI LLGSL LSAI L GYL LLR L 383
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
35-406
4.88e-88
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 271.65
E-value: 4.88e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 35 F LRT E QI GG LV L LG A T ALA LII ANS P LS DA Y QRLSAYTFGP Q -- S LHLDL S VAQ W AQ DGL LT VFF VVA GLE L KREL VI G E 112
Cdd:TIGR00773 1 F FKS E SA GG IL L VI A A ALA MVM ANS A LS EW Y HDFLHTPVQL Q ig S FVIGK S LLH W IN DGL MA VFF LLI GLE V KREL LE G A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 113 L R S P RQA AL P IAG AIGGM VV PAL LCFLIAFGA P GGSDA WA V P V ATDIAFAL A V L A ICARDL P PS L RV FLL S LAI V DDLGA 192
Cdd:TIGR00773 81 L S S L RQA IF P VIA AIGGM IA PAL IYLAFNAND P ITREG WA I P A ATDIAFAL G V M A LLGKRV P LA L KI FLL A LAI I DDLGA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 193 I LL IAL VF T AHVAFLP LL G AA AVLV V Y A L L QQFRF R GWWL Y L L L G LAA W AL V HA SGVHAT I AGV A IG LLTRV K HDP GE H e 272
Cdd:TIGR00773 161 I VI IAL FY T NDLSMAA LL V AA VAIA V L A V L NRCGV R RLGP Y M L V G VIL W FA V LK SGVHAT L AGV I IG FFIPL K GKK GE S - 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 273 s P AEA LEH RIQ P IS A GICV PLFAF FS AG IAISAGA L GAI f T DRAS LG VLI GL VV GK TV G VL L GAAV AV RA KLA E LPE ALD 352
Cdd:TIGR00773 240 - P LKR LEH VLH P WV A YLIL PLFAF AN AG VSLQGVS L NGL - T SMLP LG IIL GL LI GK PL G IF L FSWI AV KL KLA K LPE GIN 317
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2197168264 353 WRDL FAV A V VT G C GFT V S LL IA E LAF DYGEQQAR -- V K GAV LLGS LIASL L AAGL L 406
Cdd:TIGR00773 318 FKQI FAV G V LC G I GFT M S IF IA S LAF GSVDPELI tw A K LGI LLGS TTSAV L GYSW L 373
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
34-413
1.41e-148
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 426.81
E-value: 1.41e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFLR T E QI GG LV LL G A TA LALI I ANSPL SDA Y QR L SAYTF G PQ -- SLHLDLS VAQ W AQ DGL LTV FF VVA GLE L KREL VI G 111
Cdd:COG3004 3 RFLR S E AA GG IL LL L A AV LALI W ANSPL AES Y EA L LHTPL G LG ig SLHLDLS LLH W IN DGL MAI FF FLV GLE I KREL LV G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R SPR Q AALPI AG A I GGMVVPAL LCFLIAF G A P GGSDA WA V P V ATDIAFAL A VLA ICARDL P P SLRVFLL S LAIVDDLG 191
Cdd:COG3004 83 EL S SPR K AALPI IA A L GGMVVPAL IYLAFNA G T P EAARG WA I P M ATDIAFAL G VLA LLGSRV P A SLRVFLL A LAIVDDLG 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AIL L IAL VF T AHVAF L P LL G AAA V L VVY ALL QQFRF R GW W L YLLLG LAA W AL V HA SGVHAT I AGV AIG L LTRVKHDP G -- 269
Cdd:COG3004 163 AIL V IAL FY T SGLSL L A LL L AAA A L ALL ALL NRRGV R SL W P YLLLG VVL W YA V LK SGVHAT L AGV LLA L TIPARPRV G ge 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 270 - E H ESP A E A LEH RIQ P IS A GICV PLFAF FS AG IAI S AGA L G A i F T DRAS LG VLI GLV V GK TV G VLLGAAV AV RAK LA E LP 348
Cdd:COG3004 243 e E A ESP L E R LEH ALH P WV A FLIL PLFAF AN AG VSL S GLS L A A - L T SPVT LG IAL GLV L GK PL G IFGFSWL AV KLG LA R LP 321
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2197168264 349 EALD WR D L FA V AVVT G C GFT V SL L IAELAF DYG E QQARV K GAV LLGSL I A SL L AAG LLR RQV R VR 413
Cdd:COG3004 322 AGVS WR Q L YG V GLLA G I GFT M SL F IAELAF PDP E LLDAA K LGI LLGSL L A AV L GYL LLR LRL R RK 386
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
34-405
1.73e-146
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 421.04
E-value: 1.73e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFLR T E QI GG LV LL G A TA LALI I ANSPL S D A Y QR L SAYTF G PQ -- S L H L D LS VAQ W AQ DGL LTV FF V V A GLE L KREL VI G 111
Cdd:pfam06965 2 RFLR S E AA GG IL LL A A AV LALI W ANSPL A D S Y EA L WHTPL G VG fg G L S L S LS LHH W IN DGL MAI FF F V V GLE I KREL LV G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R SPR Q AALP IAG A I GGMVVPAL LCFLIAF G A PG GS d A WA V P V ATDIAFAL A VLA ICARDL P P SLRVFLL S LAIVDDLG 191
Cdd:pfam06965 82 EL S SPR K AALP VIA A L GGMVVPAL IYLAFNA G G PG AR - G WA I P M ATDIAFAL G VLA LLGKRV P A SLRVFLL A LAIVDDLG 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AIL L IAL VF T AHVAF L P LL G AAA V L V V YA LL QQFRF R GW W L YLLLG LAA W AL V HA SGVHATIAGV AIG LL TRVKHDPG E H 271
Cdd:pfam06965 161 AIL V IAL FY T SGLSL L A LL A AAA I L A V LL LL NRLGV R RL W P YLLLG VVL W VA V LK SGVHATIAGV LLA LL IPARPPAR E S 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 272 --- E SP A E A LEH RIQ P IS A GICV PLFA FFS AG IAI S AGA LGA IF T DRAS LG VLI GLV V GK TV G VLLGAAV AV RAK LA E LP 348
Cdd:pfam06965 241 rea I SP L E R LEH ALH P WV A FLIL PLFA LAN AG VSL S GSG LGA LL T SPVT LG IAL GLV L GK PL G IFGFSWL AV KLG LA R LP 320
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2197168264 349 E ALD WR D L FA V AVVT G C GFT V SL L IAELAFD YG - E QQARV K GAV LLGSL I A SL L AAGL 405
Cdd:pfam06965 321 E GVT WR Q L LG V GLLA G I GFT M SL F IAELAFD DE l E LLDEA K LGI LLGSL L A AV L GYLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
34-408
1.30e-105
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 317.21
E-value: 1.30e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFL RT E QI GG LV L LG A T ALA L I I ANSPLS DA Y QR - L SAY - TFGPQSLHLDL S VAQ W AQ DGL LT VFF VVA GLE L KREL VI G 111
Cdd:PRK09560 7 RFL KS E AA GG IL L MA A A ALA M I V ANSPLS EG Y FS f L HTP v AIQIGAFSIGK S LLH W IN DGL MA VFF LLV GLE I KREL LE G 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 E L R S PR Q AA LP IAG A I GGMVVPAL LCFLIAFGA P GGSDA WA V P V ATDIAFAL A VLA ICARDL P P SL R VFLL S LAI V DDLG 191
Cdd:PRK09560 87 Q L S S WQ Q RI LP AIA A V GGMVVPAL IYAAFNYNN P ETLRG WA I P A ATDIAFAL G VLA LLGKRV P V SL K VFLL A LAI I DDLG 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AI LL IAL VF T AHVAFLP L LG AA AVLV V YA LL QQFRFRGWWL YL LL G LAA W AL V HA SGVHAT I AGV AIGLLTRV K HDP G EH 271
Cdd:PRK09560 167 AI VI IAL FY T SDLSLPA L AL AA IAIA V LF LL NRLGVTKLTP YL IV G AIL W FA V LK SGVHAT L AGV VLAFCIPL K GKK G DE 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 272 ESP AEA LEH RIQ P IS A GICV PLFAF FS AG IAI s AG ALGAIF T DRAS LG VLI GL VV GK T VGV LLGAAV AV RAK LA E LPE AL 351
Cdd:PRK09560 247 ESP LHH LEH ALH P WV A FAIL PLFAF AN AG VSL - AG ISLSSL T SPVP LG IAL GL FL GK Q VGV FGFSWL AV KLG LA K LPE GA 325
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2197168264 352 D W RDLFA V A V VT G C GFT V SL L I AE LAF DYG E Q - QARVKGAV LLGSL IASL L AAG LLR R 408
Cdd:PRK09560 326 N W KQIYG V S V LC G I GFT M SL F I GS LAF GAS E E l LTEARLGI LLGSL LSAI L GYL LLR L 383
nhaA
PRK09561 sodium/proton antiporter NhaA;
34-407
2.49e-96
sodium/proton antiporter NhaA;
Pssm-ID: 181955
Cd Length: 388
Bit Score: 293.71
E-value: 2.49e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 RFL RT E QI GG LV L LG A T ALA LII ANSP L S DA YQ RLSAYTFGPQ -- S L HLDLSVAQ W AQ DGL LT VFF VVA GLE L KREL VI G 111
Cdd:PRK09561 7 RFL SS E AS GG IL L II A A ALA MLM ANSP T S GW YQ DFLETPVQLR vg A L EINKPLLL W IN DGL MA VFF LLI GLE V KREL LE G 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 E L R S P RQAALP IAG AIGGM V VPAL LCF L IAFGA P GGSDA WA V P V ATDIAFAL A VLA ICARDL P PS L RV FLL S LAI V DDLG 191
Cdd:PRK09561 87 S L A S R RQAALP VIA AIGGM L VPAL IYL L FNYAD P VTREG WA I P A ATDIAFAL G VLA LLGSRV P VA L KI FLL A LAI I DDLG 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AI LL IAL VF T AHVAFLP L LG AA AVLV V Y A L L QQFRF R GWWL Y L L L G LAA W AL V HA SGVHAT I AGV AI G LLTRV K HDP G eh 271
Cdd:PRK09561 167 AI VI IAL FY T SDLSMVS L GV AA VAIA V L A V L NLCGV R RTSV Y I L V G VVL W VA V LK SGVHAT L AGV IV G FFIPL K EKH G -- 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 272 E SPAE A LEH RIQ P IS A GICV PLFAF FS AG IAISAGA L GAIFTD r AS LG VLI GL VV GK TV G VL L GAAV AV RA KLA E LPE AL 351
Cdd:PRK09561 245 R SPAE R LEH GLH P WV A FLIL PLFAF AN AG VSLQGVT L DGLTSP - LP LG IAL GL FI GK PL G IF L FSWL AV KL KLA K LPE GT 323
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2197168264 352 DWRDLF AV A V VT G C GFT V S LL IA E LAF DYGEQQARV -- K GAV L L GSL IASLLAAGL LR 407
Cdd:PRK09561 324 TFKQIY AV G V LC G I GFT M S IF IA S LAF GGVDPELIN ya K LGI L I GSL LSAVIGYSW LR 381
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
35-406
4.88e-88
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 271.65
E-value: 4.88e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 35 F LRT E QI GG LV L LG A T ALA LII ANS P LS DA Y QRLSAYTFGP Q -- S LHLDL S VAQ W AQ DGL LT VFF VVA GLE L KREL VI G E 112
Cdd:TIGR00773 1 F FKS E SA GG IL L VI A A ALA MVM ANS A LS EW Y HDFLHTPVQL Q ig S FVIGK S LLH W IN DGL MA VFF LLI GLE V KREL LE G A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 113 L R S P RQA AL P IAG AIGGM VV PAL LCFLIAFGA P GGSDA WA V P V ATDIAFAL A V L A ICARDL P PS L RV FLL S LAI V DDLGA 192
Cdd:TIGR00773 81 L S S L RQA IF P VIA AIGGM IA PAL IYLAFNAND P ITREG WA I P A ATDIAFAL G V M A LLGKRV P LA L KI FLL A LAI I DDLGA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 193 I LL IAL VF T AHVAFLP LL G AA AVLV V Y A L L QQFRF R GWWL Y L L L G LAA W AL V HA SGVHAT I AGV A IG LLTRV K HDP GE H e 272
Cdd:TIGR00773 161 I VI IAL FY T NDLSMAA LL V AA VAIA V L A V L NRCGV R RLGP Y M L V G VIL W FA V LK SGVHAT L AGV I IG FFIPL K GKK GE S - 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 273 s P AEA LEH RIQ P IS A GICV PLFAF FS AG IAISAGA L GAI f T DRAS LG VLI GL VV GK TV G VL L GAAV AV RA KLA E LPE ALD 352
Cdd:TIGR00773 240 - P LKR LEH VLH P WV A YLIL PLFAF AN AG VSLQGVS L NGL - T SMLP LG IIL GL LI GK PL G IF L FSWI AV KL KLA K LPE GIN 317
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2197168264 353 WRDL FAV A V VT G C GFT V S LL IA E LAF DYGEQQAR -- V K GAV LLGS LIASL L AAGL L 406
Cdd:TIGR00773 318 FKQI FAV G V LC G I GFT M S IF IA S LAF GSVDPELI tw A K LGI LLGS TTSAV L GYSW L 373
nhaA
PRK14855 pH-dependent sodium/proton antiporter; Provisional
32-415
8.54e-79
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 237836
Cd Length: 423
Bit Score: 249.79
E-value: 8.54e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 32 VV RF LRT E QIG GL V L L G ATAL A L I I ANSP LSDA Y QR L -- SAYTFGPQSLH LDLS VAQ W AQ DGL LT VFF VVA GLE L KREL V 109
Cdd:PRK14855 9 FQ RF VES E AFA GL L L V G TAVA A F I W ANSP WREG Y FT L qh THLALSLGGWS LDLS LEH W VN DGL MA VFF LLV GLE I KREL L 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 110 IGEL R SPRQAAL PIAG A I GGM V VPA L L CFLIAF G A PG G S d A W A VP V ATDIAFAL A VLA ICARDL P PS L R VFL LS LAIVDD 189
Cdd:PRK14855 89 IGEL S SPRQAAL AVVA A L GGM L VPA A L YTALNA G G PG A S - G W G VP M ATDIAFAL G VLA LLGSRV P LG L K VFL TA LAIVDD 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 190 LGA I L L IAL VF T AHVAF L P LL G AA AVLVVYA L LQQFRFRGWWL Y LL LG LAA W AL V HA SG V H A T I AGV AIG L LTRV - KH DP 268
Cdd:PRK14855 168 LGA V L V IAL FY T SGLNL L A LL L AA LTWALAL L AGRLGVTSLKI Y AV LG ALL W FF V LK SG L H P T V AGV LLA L AVPI r RR DP 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 269 GEH ------------------------------ E SP AEA LEH RIQ P I S AGICV P L FA F F S AG IAI S A G A LG AI ftdra SL 318
Cdd:PRK14855 248 LPY laslldaaapgrpevvgarlrdledllera Q SP LHR LEH ALH P W S TFLIL P V FA L F N AG VSV S G G G LG TV ----- SL 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 319 GV LI GL VV GK TV GV LL GA AV AVR AK LA E LP EALD W RDLFAVAVVT G C GFT V SL L I AE LAF DYGEQQARV K GA VL LG S LI A 398
Cdd:PRK14855 323 GV FL GL LL GK PL GV VG GA WL AVR LG LA S LP RRVN W LHMLGAGLLA G I GFT M SL F I SN LAF ADAALLTQA K LG VL AA S VL A 402
410
....*....|....*..
gi 2197168264 399 S LL A AG L L RRQ VR VRTR 415
Cdd:PRK14855 403 A LL G AG W L WWA VR GQPG 419
nhaA
PRK14856 sodium/proton antiporter NhaA;
34-408
1.65e-77
sodium/proton antiporter NhaA;
Pssm-ID: 184858
Cd Length: 438
Bit Score: 246.63
E-value: 1.65e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 34 R F LRT E QI GG LV L LGATA LA LII ANS P L SDA Y QR L SAYT FG P Q -- SLHLDL S VAQ W AQ D G L LTV FF VVA GLE L KREL VI G 111
Cdd:PRK14856 16 N F IKS E SF GG IF L FLNAV LA MVV ANS F L KES Y FA L WHTP FG F Q ig DFFIGF S LHN W ID D V L MAL FF LMI GLE I KREL LF G 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 112 EL R S PRQ A AL P IAG A I GGM VV P A L LC F LIAFGA P G g SDAWAV P V ATDIAFAL A V LAICARDL P PS L R VFL LS LA IV DDLG 191
Cdd:PRK14856 96 EL S S FKK A SF P VIA A L GGM IA P G L IY F FLNADT P S - QHGFGI P M ATDIAFAL G V IMLLGKRV P TA L K VFL IT LA VA DDLG 174
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 192 AI LL IAL VF T AHVA F LP LLGA AA V LV V Y A L L QQFRF R GWWL YLLLG LAA W AL VH A SG V HATIA G V AIGLLTR VK ------ 265
Cdd:PRK14856 175 AI VV IAL FY T TNLK F AW LLGA LG V VL V L A V L NRLNV R SLIP YLLLG VLL W FC VH Q SG I HATIA A V VLAFMIP VK ipkdsk 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 266 ---------------------------- H DPG E H ---- E SP A E A LEH RIQ PIS AGICV PLFAF FS AG IAISAGALGAI ft 313
Cdd:PRK14856 255 nvellelgkryaetssgalltkeqqeil H SIE E K asal Q SP L E R LEH FLA PIS GYFIM PLFAF AN AG VSVDSSINLEV -- 332
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 314 D RAS LGV LI GL VV GK TV G VL L GAAVAVRA K LAEL P EALD W RDLFAVAVVT G C GFT V S LL I AE LAF DYGEQQ A R -- V K G A V 391
Cdd:PRK14856 333 D KVL LGV IL GL CL GK PL G IF L ITFISEKL K ITAR P KGIS W WHILGAGLLA G I GFT M S MF I SN LAF TSEHKD A M ev A K I A I 412
410
....*....|....*..
gi 2197168264 392 LLGSLI ASLLA A GL L RR 408
Cdd:PRK14856 413 LLGSLI SGIIG A LY L FA 429
nhaA
PRK14854 pH-dependent sodium/proton antiporter; Provisional
39-414
5.35e-56
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 184856
Cd Length: 383
Bit Score: 189.29
E-value: 5.35e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 39 E Q IGGL V L LG A TA LA LIIA NSPL SDA Y QR L SAY -- TF G PQS L HL D LSVAQ W AQ DGL LTVF F VVA GLE L KRE LVI G E L RS P 116
Cdd:PRK14854 9 E L IGGL I L FS A AL LA IVVN NSPL ASY Y AM L ETI nv KL G IEN L VI D KNLMH W IN DGL MAIY F LYI GLE I KRE IIV G T L SK P 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 117 RQAAL P IAG A IG G MVV P A L L c F L IAFGAPGGSDA WA V P V ATDIAF A L AV LA ICARDL P PS L RVFLLSL AI V DD LG AI LL I 196
Cdd:PRK14854 89 SNIIT P AIA A FA G LAM P S L I - Y L SINHDIKVING WA I P S ATDIAF T L GI LA LLGTRV P AK L KLLVITI AI F DD IA AI AI I 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 197 A LVF T AHVAF L P L - LG AAAV L VVYALLQQ F RFRGWWL Y LL LG LA AW ALVHA SGVHAT I AG VAIG L LTRVKHD pg EHE SPA 275
Cdd:PRK14854 168 A IFY T KSLSL L S L s LG TLFI L AMIICNRI F KINRSSV Y VV LG FF AW FCTIK SGVHAT L AG FTTA L CIPFREN -- DKD SPA 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 276 EAL E HRIQ P ISAGICV P L FAF FS AGI AI S a G ALGA I FTDRAS LG VLI GL V VGK TV G VLLGA AV AVRA K LAE L P E ALDWRD 355
Cdd:PRK14854 246 NFM E DSLH P WIIYFIL P V FAF AN AGI SF S - G ISFS I LFEPIT LG IIL GL F VGK QL G IFSIL AV FKKL K WFK L G E SFSNLQ 324
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2197168264 356 L FAVAVVT G C GFT V SL L I AE LAF DYGEQQARV K GA V LL GS LIASLLAAGL LR RQ V RVRT 414
Cdd:PRK14854 325 L YGISLLC G I GFT M SL F I GV LAF NDTHLLNAI K IG V VV GS VLSGFFGYIV LR FI V TNPS 383
KefB
COG0475 Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
93-408
1.90e-03
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 40.13
E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 93 LTVFFVVA GLEL K relv IGE LR SPRQA AL P I AGA ig GMVV P A LL C FL I A FGA pgg SDAW A VPVATDI A F A LAVL AI CAR - 171
Cdd:COG0475 63 VVLLLFLI GLEL D ---- LKR LR KMGRR AL G I GLL -- QVLL P F LL G FL L A LLL --- GLSL A AALFLGA A L A ATST AI VLK v 133
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 172 ----- D L PPS L RVFL L SL A IV DD LG AILL I ALV FT ----------- AHVAFLP LL GA A AV L V V YAL L QQFR FR GWWLYLL 235
Cdd:COG0475 134 lkelg L L KTP L GQLI L GV A LF DD IA AILL L ALV PA lagggsvagsl LLALLKA LL FL A LL L L V GRY L LRRL FR LVARTRS 213
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 236 LG L AAWALV ---------- HAS G VH A TIAGVAI GL LTR vkhdpge HESPAEA LE HR I Q P IS a GICV PLF a F F S A G IAISA 305
Cdd:COG0475 214 RE L FLLFAL llvllaaala ELL G LS A ALGAFLA GL VLA ------- ESEYRHE LE EK I E P FG - DLFL PLF - F V S V G LSLDL 284
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2197168264 306 G AL GAIFT dr AS L GVLIGLV VGK TV G VL L G A AVA vraklaelpe A L DW R DLFAVAVVTGCGFTVS L LI A E L AFDY G EQQA 385
Cdd:COG0475 285 S AL LSNPL -- LA L LLVLAAI VGK LL G AY L A A RLF ---------- G L SR R EALRIGLLLAPRGEFA L VL A S L GLSA G LISP 352
330 340
....*....|....*....|...
gi 2197168264 386 RVKG A VL L GS L IAS LL AAG LLR R 408
Cdd:COG0475 353 ELFA A LV L VV L LTT LL TPL LLR L 375
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
