Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase ...
1-180
8.69e-53
Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase UbiX is part of the Pathway/BioSystem: Ubiquinone biosynthesis
The actual alignment was detected with superfamily member COG0163:
Pssm-ID: 439933 Cd Length: 187 Bit Score: 166.37 E-value: 8.69e-53
Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase ...
1-180
8.69e-53
Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase UbiX is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 439933 Cd Length: 187 Bit Score: 166.37 E-value: 8.69e-53
UbiX family flavin prenyltransferase; UbiX partners with UbiD for decarboxylation of the ...
2-177
1.73e-38
UbiX family flavin prenyltransferase; UbiX partners with UbiD for decarboxylation of the 3-octaprenyl-4-hydroxybenzoate precursor during ubiquinone biosynthesis, but the role of UbiX is as a flavin prenyltransferase that provides a cofactor UbiD requires.In E.coli, the protein UbiX (3-octaprenyl-4-hydroxybenzoate carboxy-lyase) has been shown to be involved in the third step of ubiquinone biosynthesis, the reaction [3-octaprenyl-4-hydroxybenzoate = 2-octaprenylphenol + CO2]. The knockout of the homologous protein in yeast confers sensitivity to phenylacrylic acid. Members are not restricted to ubiquinone-synthesizing species. This family represents a distinct clade within the flavoprotein family of pfam02441.
Pssm-ID: 129515 Cd Length: 181 Bit Score: 129.90 E-value: 1.73e-38
Flavoprotein; This family contains diverse flavoprotein enzymes. This family includes ...
1-146
1.23e-19
Flavoprotein; This family contains diverse flavoprotein enzymes. This family includes epidermin biosynthesis protein, EpiD, which has been shown to be a flavoprotein that binds FMN. This enzyme catalyzes the removal of two reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond. This family also includes the B chain of dipicolinate synthase a small polar molecule that accumulates to high concentrations in bacterial endospores, and is thought to play a role in spore heat resistance, or the maintenance of heat resistance. dipicolinate synthase catalyzes the formation of dipicolinic acid from dihydroxydipicolinic acid. This family also includes phenyl-acrylic acid decarboxylase (EC:4.1.1.-).
Pssm-ID: 426775 [Multi-domain] Cd Length: 177 Bit Score: 81.27 E-value: 1.23e-19
Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase ...
1-180
8.69e-53
Flavin prenyltransferase UbiX [Coenzyme transport and metabolism]; Flavin prenyltransferase UbiX is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 439933 Cd Length: 187 Bit Score: 166.37 E-value: 8.69e-53
UbiX family flavin prenyltransferase; UbiX partners with UbiD for decarboxylation of the ...
2-177
1.73e-38
UbiX family flavin prenyltransferase; UbiX partners with UbiD for decarboxylation of the 3-octaprenyl-4-hydroxybenzoate precursor during ubiquinone biosynthesis, but the role of UbiX is as a flavin prenyltransferase that provides a cofactor UbiD requires.In E.coli, the protein UbiX (3-octaprenyl-4-hydroxybenzoate carboxy-lyase) has been shown to be involved in the third step of ubiquinone biosynthesis, the reaction [3-octaprenyl-4-hydroxybenzoate = 2-octaprenylphenol + CO2]. The knockout of the homologous protein in yeast confers sensitivity to phenylacrylic acid. Members are not restricted to ubiquinone-synthesizing species. This family represents a distinct clade within the flavoprotein family of pfam02441.
Pssm-ID: 129515 Cd Length: 181 Bit Score: 129.90 E-value: 1.73e-38
Flavoprotein; This family contains diverse flavoprotein enzymes. This family includes ...
1-146
1.23e-19
Flavoprotein; This family contains diverse flavoprotein enzymes. This family includes epidermin biosynthesis protein, EpiD, which has been shown to be a flavoprotein that binds FMN. This enzyme catalyzes the removal of two reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond. This family also includes the B chain of dipicolinate synthase a small polar molecule that accumulates to high concentrations in bacterial endospores, and is thought to play a role in spore heat resistance, or the maintenance of heat resistance. dipicolinate synthase catalyzes the formation of dipicolinic acid from dihydroxydipicolinic acid. This family also includes phenyl-acrylic acid decarboxylase (EC:4.1.1.-).
Pssm-ID: 426775 [Multi-domain] Cd Length: 177 Bit Score: 81.27 E-value: 1.23e-19
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
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