|
Name |
Accession |
Description |
Interval |
E-value |
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
2-405 |
1.24e-29 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 119.28 E-value: 1.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 2 KRNMVTAFLSIFGGRIFIVLSSVVLTPLLITTLGFELYGRYGTLTAVFGISTILMSSGINSGARKFLAEDRSisDWQTHV 81
Cdd:COG2244 1 LKKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYRE--EELRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 82 FGYYFRLGTVLAVLTALAFAAAARFgVVTRFLGPEYVVGFYGLAGLTIATQFREYARRSLMGLKQEHLSEPLRVLNKVGT 161
Cdd:COG2244 79 LSTALLLRLLLSLLLALLLLLLAPF-IAALLGEPELALLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 162 RLALIGIAYLGYEIGGLmvglivvnslvallalwwvrknvslrgivsttprgfptkeLFSFNHLSVVYMLFLTSMYHVDV 241
Cdd:COG2244 158 LLLALLLALLGLGLWGL----------------------------------------VLKYSLPLLLSGLLGLLLTNLDR 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 242 LMLASHVTETRVGYYKSALVISQFLWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLSLGLAALAKD 321
Cdd:COG2244 198 LLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPP 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 322 FVPLYLGSGSMPVVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHGILGAAVATTTR 401
Cdd:COG2244 278 LLSLLFGPEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIPRYGLVGAAIATLLS 357
|
....
gi 2209810512 402 LLLA 405
Cdd:COG2244 358 YLVL 361
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
9-405 |
7.17e-29 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 118.03 E-value: 7.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 9 FLSIFGGRIFIVLSSVVLTPLLITTLGFELYGRYGTLTAVFGISTILMSSGINSGARKFLAEDR--SISDWQTHVFGYYF 86
Cdd:cd13128 5 SGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRkeKIREIISTSLVLKL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 87 RLGTVLAVLTALafaaaarFGVVTRFLGPEYVVGFYGLAGLTIATQFREYARRSLMGLKQEHLSEPLRVLNKVGTRLALI 166
Cdd:cd13128 85 ILGILALLLLFL-------FAFLIAFYDPELVLLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIESVLSLILAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 167 GIAYLGYEIGGLMVGLIVVNSLVALLALWWVRKNVSLRGIVSTTPRGFptKELFSFnhlsvVYMLFLTS-----MYHVDV 241
Cdd:cd13128 158 ILVLLGGGLIGFALAYLIASVLSAILLLYIYRKKILLPKFFSFDLKLA--KELLRF-----SIPLALSGifsliYTRIDT 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 242 LMLASHVTETRVGYYKSALVISQFLWVIPRSIQSMLVQSVSDLWAdERIDQINEIASRVTRYGMLVIVLLSLGLAALAKD 321
Cdd:cd13128 231 IMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELYK-NDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 322 FVPLYLGSGSMPVVTPLLILLPGTIGFAVVRP----ILAISHAKADMKpliaATGAAAVLNIVLNVVLIPRHGILGAAVA 397
Cdd:cd13128 310 IITLLFGEEYLPAALVLQILAWGFLFIFLNGIfgsiLQAIGKQKLTLK----ILLIGALLNVILNLLLIPKYGIIGAAIA 385
|
....*...
gi 2209810512 398 TTTRLLLA 405
Cdd:cd13128 386 TLISEFII 393
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
337-405 |
3.30e-05 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 43.72 E-value: 3.30e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2209810512 337 PLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHGILGAAVATTTRLLLA 405
Cdd:pfam14667 1 VLQILALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILNLLLIPLFGIVGAAIATVISLLVV 69
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
2-405 |
1.24e-29 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 119.28 E-value: 1.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 2 KRNMVTAFLSIFGGRIFIVLSSVVLTPLLITTLGFELYGRYGTLTAVFGISTILMSSGINSGARKFLAEDRSisDWQTHV 81
Cdd:COG2244 1 LKKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYRE--EELRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 82 FGYYFRLGTVLAVLTALAFAAAARFgVVTRFLGPEYVVGFYGLAGLTIATQFREYARRSLMGLKQEHLSEPLRVLNKVGT 161
Cdd:COG2244 79 LSTALLLRLLLSLLLALLLLLLAPF-IAALLGEPELALLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 162 RLALIGIAYLGYEIGGLmvglivvnslvallalwwvrknvslrgivsttprgfptkeLFSFNHLSVVYMLFLTSMYHVDV 241
Cdd:COG2244 158 LLLALLLALLGLGLWGL----------------------------------------VLKYSLPLLLSGLLGLLLTNLDR 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 242 LMLASHVTETRVGYYKSALVISQFLWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLSLGLAALAKD 321
Cdd:COG2244 198 LLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPP 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 322 FVPLYLGSGSMPVVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHGILGAAVATTTR 401
Cdd:COG2244 278 LLSLLFGPEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIPRYGLVGAAIATLLS 357
|
....
gi 2209810512 402 LLLA 405
Cdd:COG2244 358 YLVL 361
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
9-405 |
7.17e-29 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 118.03 E-value: 7.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 9 FLSIFGGRIFIVLSSVVLTPLLITTLGFELYGRYGTLTAVFGISTILMSSGINSGARKFLAEDR--SISDWQTHVFGYYF 86
Cdd:cd13128 5 SGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRkeKIREIISTSLVLKL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 87 RLGTVLAVLTALafaaaarFGVVTRFLGPEYVVGFYGLAGLTIATQFREYARRSLMGLKQEHLSEPLRVLNKVGTRLALI 166
Cdd:cd13128 85 ILGILALLLLFL-------FAFLIAFYDPELVLLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIESVLSLILAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 167 GIAYLGYEIGGLMVGLIVVNSLVALLALWWVRKNVSLRGIVSTTPRGFptKELFSFnhlsvVYMLFLTS-----MYHVDV 241
Cdd:cd13128 158 ILVLLGGGLIGFALAYLIASVLSAILLLYIYRKKILLPKFFSFDLKLA--KELLRF-----SIPLALSGifsliYTRIDT 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 242 LMLASHVTETRVGYYKSALVISQFLWVIPRSIQSMLVQSVSDLWAdERIDQINEIASRVTRYGMLVIVLLSLGLAALAKD 321
Cdd:cd13128 231 IMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELYK-NDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 322 FVPLYLGSGSMPVVTPLLILLPGTIGFAVVRP----ILAISHAKADMKpliaATGAAAVLNIVLNVVLIPRHGILGAAVA 397
Cdd:cd13128 310 IITLLFGEEYLPAALVLQILAWGFLFIFLNGIfgsiLQAIGKQKLTLK----ILLIGALLNVILNLLLIPKYGIIGAAIA 385
|
....*...
gi 2209810512 398 TTTRLLLA 405
Cdd:cd13128 386 TLISEFII 393
|
|
| MATE_tuaB_like |
cd13127 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
9-405 |
5.66e-07 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240532 [Multi-domain] Cd Length: 406 Bit Score: 51.72 E-value: 5.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 9 FLSIFGGRIFIVLSSVVLTPLLittlGFELYGRYGTLTAVFGISTILMSSGINSGarkfLAEDRSISDWQTH-VFGYYFR 87
Cdd:cd13127 9 AISQVVVQLLQFVVTIILARLL----TPEDFGLVAMATVFIAFAQLFSDLGLSSA----LIQRKDLTEEDLStVFWLNLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 88 LGTVlavltalafaaaarFGVVTRFLGPeYVVGFYGLAGLT--------------IATQFREYARRSLMgLKQEHLSEpl 153
Cdd:cd13127 81 LGLL--------------LYLLLFLLAP-LIAAFYNEPELIpllrvlslsfllsgLGSVPRALLQRELR-FKKLAIIE-- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 154 rVLNKVGTRLALIGIAYLGYEIGGLMVGLIVVNSLVALLALWWVRKNVSLRgivsttPRGFPTKELFSFN-HLSVVYML- 231
Cdd:cd13127 143 -LISTLVSGVVAIVLALLGFGVWALVAQQLVGALVSTVLLWILSRWRPRLS------FSLASLKELLSFGsKLLGSNLLn 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 232 FLTSmyHVDVLMLASHVTETRVGYYK-----SALVISQFLWVIPRSIQSMLVQSVSDlwaderIDQINEIASRVTRYGML 306
Cdd:cd13127 216 YFSR--NLDNLIIGKFLGAAALGYYSrayrlALLPVQNITGPITRVLFPALSRLQDD------PERLRRAYLKALRLLAL 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 307 VIVLLSLGLAALAKDFVPLYLGSGSMPVVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLI 386
Cdd:cd13127 288 ITFPLMVGLALLAEPLVLLLLGEKWLPAVPILQILALAGLFQPLSSLNGSLLLALGRTDLLLKLGLIKAVLTVLALLIGI 367
|
410
....*....|....*....
gi 2209810512 387 PrHGILGAAVATTTRLLLA 405
Cdd:cd13127 368 P-YGIIGVAIAYVIASLLS 385
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
337-405 |
3.30e-05 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 43.72 E-value: 3.30e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2209810512 337 PLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHGILGAAVATTTRLLLA 405
Cdd:pfam14667 1 VLQILALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILNLLLIPLFGIVGAAIATVISLLVV 69
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
164-399 |
4.44e-05 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 45.91 E-value: 4.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 164 ALIGIAYLGYEIGGLMVGLIVVNSLVALLALWWVRKNvslrgivsttprGFPTKELFSFNHLSVVYMLFL-------TSM 236
Cdd:cd13123 163 LLLLAPLFDLGIYALAWGVLLGGVLQLLVQLPALRRL------------GFRFRPRLDFRDPGVRRVLKLmlpallgVSV 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 237 YHVDVL---MLASHVTETRVGYYKSALVISQF-LWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLS 312
Cdd:cd13123 231 SQINLLvdtILASFLPEGSISALYYADRLYQLpLGIFGVAIATALLPRLSRLAAAGDLDEFRRTLSRGLRLVLFLLLPAA 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 313 LGLAALAKDFVPLYLGSGSMP------VVTPLLILLPGTIGFAVVRPILAISHAKADMK-PLIAATgAAAVLNIVLNVVL 385
Cdd:cd13123 311 VGLIVLAEPIVRLLFERGAFTaedtlmTASALAAYALGLPAFALVKLLSRAFYALKDTKtPVKIAV-IAVAVNILLNLLL 389
|
250
....*....|....
gi 2209810512 386 IPRHGILGAAVATT 399
Cdd:cd13123 390 IKPLGHVGLALATS 403
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
166-405 |
5.53e-05 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 45.54 E-value: 5.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 166 IGIAYLGYEIGGLMvglivvnSLVALLALWWVRKNVSLRGIVSTTPRGFPTKELF----------SFNHLsVVYMLFLTS 235
Cdd:cd13124 176 AAGATFGAVIGALA-------GLLVLLYYYRKKRRELKRLLRKSPRSKISTKEILkellsyaipiTLSSL-ILPLLQLID 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 236 MYHVDVLMLASHVTETRV----GYYKS-ALVISQFLWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVL 310
Cdd:cd13124 248 SFTVPRRLQAAGLSESEAtalyGILTGrAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRLTLLIGLP 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 311 LSLGLAALAKdfvPLYLG-SGSMPVVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRH 389
Cdd:cd13124 328 AAVGLAVLAE---PINTLlFGDSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLNYVLIPIF 404
|
250
....*....|....*.
gi 2209810512 390 GILGAAVATTTRLLLA 405
Cdd:cd13124 405 GIYGAAIATVIGFLVA 420
|
|
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
176-405 |
1.15e-03 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 41.30 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 176 GGLMVGLIV--VNSLVALLALWWVRKNVSLRGI-VSTTPRGFPTKEL----------FSFNHLSVVYMLFLTSMYHVDVL 242
Cdd:COG5841 185 AGATFGAVIgaLAGLLVLLYYYRKRKKKLKRLLeKSKTKSKESSKDIlkellriaipITLSSLVLPLFQLIDSFTVPRRL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 243 MLA---SHVTETRVGYYKS-ALVISQFLWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLslglaal 318
Cdd:COG5841 265 QAAglsASEATSLYGILSGmAQPLVNLPTVLATALATSLVPAISEAFAKKDRKLVRRRINQALRLTLLIGLPA------- 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 319 akdFVPLYLGS--------GSMPVVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHG 390
Cdd:COG5841 338 ---AVGLAVLAepintllfGNPEGGGILAILAPSAIFLSLQQVTTGILQGLGKQKIPVINLLIGLLVKIILNYLLVPLFG 414
|
250
....*....|....*
gi 2209810512 391 ILGAAVATTTRLLLA 405
Cdd:COG5841 415 IYGAALATVIGYLVA 429
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
338-399 |
2.39e-03 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 40.13 E-value: 2.39e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2209810512 338 LLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLI--PRHGILGAAVATT 399
Cdd:COG0534 130 LRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLIGNVLNIVLDPLLIfgGGLGVAGAALATV 193
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
155-405 |
4.05e-03 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 39.61 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 155 VLNKVGTRLALIGIAYLGYEIGGLMVGLIVVNSLVALLALWWVRKNVSLRGIVST--TPRGFPTKELFSFNHLSVVYMLF 232
Cdd:cd12082 155 LLNILLDPLLIFGLGPPELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSllKPDLELLRRLLRIGLPSAIQNSL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 233 LTSMYHVDVLMLASHVTETRVGYYKSALVISQFLWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLS 312
Cdd:cd12082 235 LSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLG 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 313 LGLAALAKDFVPLYLGSGSMPVVT-PLLILLPGTIGFAVVRPIL--AISHAKADMKPLIAATGAAAVLNIVLNVVLIPRH 389
Cdd:cd12082 315 LLILLFPEPILSLFTNDPEFLELAvSYLRILAIYYLFVGIGYVLqaGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLAYLG 394
|
250
....*....|....*..
gi 2209810512 390 -GILGAAVATTTRLLLA 405
Cdd:cd12082 395 lGLYGIWLALVISLILA 411
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
338-400 |
5.06e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 39.43 E-value: 5.06e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 338 LLILLPGTIgFAVVRPIL-AISHAKADMKPLIAATGAAAVLNIVLNVVLI------PRHGILGAAVATTT 400
Cdd:cd13140 128 LRIVALGLI-FSFLNPVFtGIFNALGDSKTPFIINAIGLVLNIILDPLLIfgfgpfPALGVAGAALATVL 196
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
164-399 |
6.00e-03 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 38.98 E-value: 6.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 164 ALIGIAYLGYEIGGLMVGlIVVNSLVALLALWWV--RKNVSLRgivsttPR-GFPTKELFSFNHLsVVYMLFLTSMYHVD 240
Cdd:COG0728 170 LLLLAPLFGPGIYALAWG-VLLGGVLQLLIQLPAlrRLGLRLR------PRfDLRDPGVRRVLKL-MLPALLGVSVSQIN 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 241 VL---MLASHVTETRVGYYKSALVISQF-LWVIPRSIQSMLVQSVSDLWADERIDQINEIASRVTRYGMLVIVLLSLGLA 316
Cdd:COG0728 242 LLvdtILASFLPEGSVSALYYADRLYQLpLGLFGVAIGTALLPRLSRAAAAGDLEEFRRTLSRGLRLVLLLTLPAAVGLI 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 317 ALAKDFVPLYLGSGSMP------VVTPLLILLPGTIGFAVVRPILAISHAKADMKPLIAATGAAAVLNIVLNVVLIPRHG 390
Cdd:COG0728 322 VLAEPIVRLLFERGAFTaedtalTALALAAYALGLPAFALVKVLARAFYARQDTRTPVRIAVIAVVVNIVLNLLLVPPLG 401
|
....*....
gi 2209810512 391 ILGAAVATT 399
Cdd:COG0728 402 HAGLALATS 410
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
338-400 |
6.55e-03 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 39.03 E-value: 6.55e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2209810512 338 LLILLPGTIGFAVVRPILAISHAKADMK-PLIAaTGAAAVLNIVLNVVLI------PRHGILGAAVATTT 400
Cdd:cd13137 123 LRIVLLGIPFFFLSLVGNAALRGAGDTKtPMYI-MIIVNVLNIVLDYVLIfglwgfPGLGVAGAALATVI 191
|
|
| |
