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Conserved domains on  [gi|2225491125|ref|WP_245522464|]
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energy-coupling factor transporter transmembrane component T [Treponema denticola]

Protein Classification

energy-coupling factor transporter transmembrane component T( domain architecture ID 15320375)

energy-coupling factor transporter transmembrane component T is a part of the prokaryotic ECF (energy-coupling factor) transporters that mediate micronutrient uptake

Gene Ontology:  GO:0055085
PubMed:  24156876
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
EcfT cd16914
T component of ECF-type transporters; The transmembrane component (T component) of the energy ...
 28-204 5.65e-30

T component of ECF-type transporters; The transmembrane component (T component) of the energy coupling-factor (ECF)-type transporter is a transmembrane protein important for vitamin uptake in prokaryotes. In addition to the T component, energy-coupling factor (ECF) transporters contain an energy-coupling module that consists of two ATP-binding proteins (known as the A and A' components) and a substrate-binding (S) component. ECF transporters comprise a subgroup of ATP-binding cassette (ABC) transporters that do not make use of water-soluble substrate binding proteins or domains, but instead employ integral membrane proteins for substrate binding, the S component, in contrast to classical ABC importers. The T component links the S component to the ATP-binding subcomplex that is composed of the A and A' components.


:

Pssm-ID: 410987  Cd Length: 233  Bit Score: 110.71  E-value: 5.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  28 RQWKRFGRGVIMLAVGYGLLIAMPHLPGLLNFI--------ALMCGGILTRFAVTVVMGGYLIGTTSVSEFISAMERLHI 99
Cdd:cd16914    47 LRLLKRLLFLLLFLLLILLLLPLGGGGGVFGLGglgitlegLLYALLLALRLLAIVLAALLLLLTTPPSELLAALRRLGV 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125 100 PQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRL--GGVRPGEVVEYQLVPMITSTVRIGEDLSAAALTRGLGSPIKR 177
Cdd:cd16914   127 PPKLALLLSLALRFIPLLLEEARRIRDAQRARGGDFsgGGLRRLRSLGPLLGPLLVRSLRRAEELALAMEARGFGGGKRR 206

                         170       180
                  ....*....|....*....|....*..
gi 2225491125 178 TNICRIGFRVQDLILLIICLAVVVMWI 204
Cdd:cd16914   207 TSYRELKFRRRDYLFLALLLLLLALLL 233
 
Name Accession Description Interval E-value
EcfT cd16914
T component of ECF-type transporters; The transmembrane component (T component) of the energy ...
 28-204 5.65e-30

T component of ECF-type transporters; The transmembrane component (T component) of the energy coupling-factor (ECF)-type transporter is a transmembrane protein important for vitamin uptake in prokaryotes. In addition to the T component, energy-coupling factor (ECF) transporters contain an energy-coupling module that consists of two ATP-binding proteins (known as the A and A' components) and a substrate-binding (S) component. ECF transporters comprise a subgroup of ATP-binding cassette (ABC) transporters that do not make use of water-soluble substrate binding proteins or domains, but instead employ integral membrane proteins for substrate binding, the S component, in contrast to classical ABC importers. The T component links the S component to the ATP-binding subcomplex that is composed of the A and A' components.


Pssm-ID: 410987  Cd Length: 233  Bit Score: 110.71  E-value: 5.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  28 RQWKRFGRGVIMLAVGYGLLIAMPHLPGLLNFI--------ALMCGGILTRFAVTVVMGGYLIGTTSVSEFISAMERLHI 99
Cdd:cd16914    47 LRLLKRLLFLLLFLLLILLLLPLGGGGGVFGLGglgitlegLLYALLLALRLLAIVLAALLLLLTTPPSELLAALRRLGV 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125 100 PQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRL--GGVRPGEVVEYQLVPMITSTVRIGEDLSAAALTRGLGSPIKR 177
Cdd:cd16914   127 PPKLALLLSLALRFIPLLLEEARRIRDAQRARGGDFsgGGLRRLRSLGPLLGPLLVRSLRRAEELALAMEARGFGGGKRR 206

                         170       180
                  ....*....|....*....|....*..
gi 2225491125 178 TNICRIGFRVQDLILLIICLAVVVMWI 204
Cdd:cd16914   207 TSYRELKFRRRDYLFLALLLLLLALLL 233
EcfT COG0619
ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];
67-205 7.76e-27

ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];


Pssm-ID: 440384  Cd Length: 249  Bit Score: 102.66  E-value: 7.76e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  67 ILTRFAVTVVMGGYLIGTTSVSEFISAMERLHIPQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRLGGVR-PGEVVE 145
Cdd:COG0619   109 LALRLLALVLAALLLLLTTPPSDLLAALRRLGVPPELALMLLLALRFIPVLLEEARRIREAQRARGGDFGKLRrRLRSLG 188

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125 146 YQLVPMITSTVRIGEDLSAAALTRGLGSPIKRTNICRIGFRVQDLILLIICLAVVVMWIL 205
Cdd:COG0619   189 PLLGPLLVRSLRRAERLALAMEARGFGGGGKRTSLRELRFSRRDYLALALLLALLAALLL 248
CbiQ pfam02361
Cobalt transport protein; This family consists of various cobalt transport proteins Most of ...
 67-176 8.76e-11

Cobalt transport protein; This family consists of various cobalt transport proteins Most of which are found in Cobalamin (Vitamin B12) biosynthesis operons. In Salmonella the cbiN cbiQ (product CbiQ in this family) and cbiO are likely to form an active cobalt transport system.


Pssm-ID: 396782  Cd Length: 215  Bit Score: 59.26  E-value: 8.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  67 ILTRFAVTVVMGGYLIGTTSVSEFISAMERLHIPQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRLGGVRPGEVVEY 146
Cdd:pfam02361 101 LALRILTLLSALLFLALTTPPIELTSSLRRLGVPLELAEILLLAYRFIPLLLEEAQRIRQAQKLRGGDSGLGIRRSYRSL 180

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2225491125 147 Q--LVPMITSTVRIGEDLSAAALTRGLGSPIK 176
Cdd:pfam02361 181 GllIAPLFIRALKRAERVAIAMEARGYTGDER 212
 
Name Accession Description Interval E-value
EcfT cd16914
T component of ECF-type transporters; The transmembrane component (T component) of the energy ...
 28-204 5.65e-30

T component of ECF-type transporters; The transmembrane component (T component) of the energy coupling-factor (ECF)-type transporter is a transmembrane protein important for vitamin uptake in prokaryotes. In addition to the T component, energy-coupling factor (ECF) transporters contain an energy-coupling module that consists of two ATP-binding proteins (known as the A and A' components) and a substrate-binding (S) component. ECF transporters comprise a subgroup of ATP-binding cassette (ABC) transporters that do not make use of water-soluble substrate binding proteins or domains, but instead employ integral membrane proteins for substrate binding, the S component, in contrast to classical ABC importers. The T component links the S component to the ATP-binding subcomplex that is composed of the A and A' components.


Pssm-ID: 410987  Cd Length: 233  Bit Score: 110.71  E-value: 5.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  28 RQWKRFGRGVIMLAVGYGLLIAMPHLPGLLNFI--------ALMCGGILTRFAVTVVMGGYLIGTTSVSEFISAMERLHI 99
Cdd:cd16914    47 LRLLKRLLFLLLFLLLILLLLPLGGGGGVFGLGglgitlegLLYALLLALRLLAIVLAALLLLLTTPPSELLAALRRLGV 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125 100 PQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRL--GGVRPGEVVEYQLVPMITSTVRIGEDLSAAALTRGLGSPIKR 177
Cdd:cd16914   127 PPKLALLLSLALRFIPLLLEEARRIRDAQRARGGDFsgGGLRRLRSLGPLLGPLLVRSLRRAEELALAMEARGFGGGKRR 206

                         170       180
                  ....*....|....*....|....*..
gi 2225491125 178 TNICRIGFRVQDLILLIICLAVVVMWI 204
Cdd:cd16914   207 TSYRELKFRRRDYLFLALLLLLLALLL 233
EcfT COG0619
ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];
67-205 7.76e-27

ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];


Pssm-ID: 440384  Cd Length: 249  Bit Score: 102.66  E-value: 7.76e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  67 ILTRFAVTVVMGGYLIGTTSVSEFISAMERLHIPQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRLGGVR-PGEVVE 145
Cdd:COG0619   109 LALRLLALVLAALLLLLTTPPSDLLAALRRLGVPPELALMLLLALRFIPVLLEEARRIREAQRARGGDFGKLRrRLRSLG 188

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125 146 YQLVPMITSTVRIGEDLSAAALTRGLGSPIKRTNICRIGFRVQDLILLIICLAVVVMWIL 205
Cdd:COG0619   189 PLLGPLLVRSLRRAERLALAMEARGFGGGGKRTSLRELRFSRRDYLALALLLALLAALLL 248
CbiQ pfam02361
Cobalt transport protein; This family consists of various cobalt transport proteins Most of ...
 67-176 8.76e-11

Cobalt transport protein; This family consists of various cobalt transport proteins Most of which are found in Cobalamin (Vitamin B12) biosynthesis operons. In Salmonella the cbiN cbiQ (product CbiQ in this family) and cbiO are likely to form an active cobalt transport system.


Pssm-ID: 396782  Cd Length: 215  Bit Score: 59.26  E-value: 8.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225491125  67 ILTRFAVTVVMGGYLIGTTSVSEFISAMERLHIPQAITIPMSVMFRMFPTIGAEWKSIRRAMGMRGIRLGGVRPGEVVEY 146
Cdd:pfam02361 101 LALRILTLLSALLFLALTTPPIELTSSLRRLGVPLELAEILLLAYRFIPLLLEEAQRIRQAQKLRGGDSGLGIRRSYRSL 180

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2225491125 147 Q--LVPMITSTVRIGEDLSAAALTRGLGSPIK 176
Cdd:pfam02361 181 GllIAPLFIRALKRAERVAIAMEARGYTGDER 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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