|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
37-758 |
0e+00 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 603.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 37 HDINFGLDLAGGVSITYQVAGENGGTPTTQE-MDDTVSKLSKRVaSELNTTEASVYKEGSDRITVEIPGATD--EIFETL 113
Cdd:PRK13024 29 KNINLGLDLQGGFEVLLEVSPADKGKKADREaLDSTVEVLRNRI-DGLGVSEPNIQREGNNRIRVELPGVQDpeRARELL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 114 STPGNLYFiREYNDQGTPNYYDPYGMGYSAFYMLsdgvtveslqASGDIVLSGEDIADAQAGVDNSGTGsEYIVELTLTS 193
Cdd:PRK13024 108 GSTAKLTF-RDVTDPPPPGVGGPVVGPDEGKDTA----------VLNPVLLSGDDLTDAGAKFDQDQTN-RPSVSLKLKS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 194 EGAKKFATATEAAYANGWT---IGIYYDGAFISVPRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRANV 270
Cdd:PRK13024 176 EGAKKWAKVTEKNSKKGPPnnrIAIVLDPKVISAPTVNQPINGGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 271 VGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDAN 350
Cdd:PRK13024 256 VGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDAN 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 351 VLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGIS 430
Cdd:PRK13024 336 VLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTRLLL 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 431 ALLYNLGFKTESFYGKAK-----------APKKIDFVSKRNIFYAISVLIIVCGIGTCVYNhtagnhAFNYSIDFVGGTA 499
Cdd:PRK13024 416 ELLVKRGDKKPFLFGVKKkkihninegvtIFDRIDFVKKRKWFLIFSIVLVIAGIIIFFIF------GLNLGIDFTGGTR 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 500 TTVTFEDGKTPsvEDLESSIEPAIISAASAADANLKNLSISHQIVNDQDqvvfKTQSLSTDASQAVNELLTTTYGATDVT 579
Cdd:PRK13024 490 YEIRTDQPVDL--EQVRADLKELGLGEVNIVTFGSDNNQVLVRTYGILS----DDEEADTEIVAKLKNALKNDKGGTIPS 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 580 YETISATISDEMTSDASWATVIALILMLIYIYFRFRdIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGY 659
Cdd:PRK13024 564 SETVGPTVGKELARNAIIAVLIALIGILLYILIRFE-WTFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGY 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 660 SINDTIVTFDRIRENQHGLRnQEQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSS 739
Cdd:PRK13024 643 SINDTVVVFDRIRENLRLYK-KKDLREIVNKSINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLIVGTYSS 721
|
730
....*....|....*....
gi 2233693744 740 ICIASQLWFSMKKKSVEKA 758
Cdd:PRK13024 722 IFIAAPLWLDLEKRRLKKK 740
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
39-438 |
6.57e-137 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 411.05 E-value: 6.57e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 39 INFGLDLAGGVSITYQV--------AGENGGTPTTQEMDDTVSKLSKRVaSELNTTEASVYKEGSDRITVEIPGATD--E 108
Cdd:COG0342 31 IKLGLDLQGGVHLLLEVdtdaaldeDGDGIREVTEEALDQAIEILRNRV-NELGVSEPVIQRQGDDRIVVELPGVQDpaE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 109 IFETLSTPGNLYFiREYNDQGTPNYYDPYGmgySAFYMLSDGVTVESLqasGDIVLSGEDIADAQAGVDNsgTGSEYIVE 188
Cdd:COG0342 110 AKELLGKTAKLEF-RLVDDSADAQAAVPAG---SELLPCRDGQPYLLL---GPVVLTGDDLTDASAGFDQ--QTGQPVVS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 189 LTLTSEGAKKFATATEAAYanGWTIGIYYDGAFISVPRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRA 268
Cdd:COG0342 181 FTLDSEGAKKFADATRENV--GKPLAIVLDGEVISAPVIQEPITGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEE 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 269 NVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVD 348
Cdd:COG0342 259 RTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVD 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 349 ANVLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRG 428
Cdd:COG0342 339 ANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRP 418
|
410
....*....|
gi 2233693744 429 ISALLYNLGF 438
Cdd:COG0342 419 LLNLLLGRRR 428
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
75-746 |
3.93e-124 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 391.78 E-value: 3.93e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 75 LSKRVAsELNTTEASVYKEGSDRITVEIPGATD--EIFETLSTPGNLYFirEYNDQGTP-----NYYDPygMGYSAFYML 147
Cdd:PRK14726 170 VRRRVA-ELGTTEPLIRRQGDDRIVVQVPGLVDpqRLKNLLNQPAKLSF--RLVDSSMPaqealNGRPP--ATSEVLYSL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 148 SD---GVTVESlqasgDIVLSGEDIADAQAGVDNSGtgSEYIVELTLTSEGAKKFATATEAAYanGWTIGIYYDGAFISV 224
Cdd:PRK14726 245 DDppvPYLVER-----RAFVSGENLVDAQPVFDPQT--NEPVVTFRLDAEGTQRFAQATQQNV--GKHFAIVLDGQVISA 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 225 PRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRI 304
Cdd:PRK14726 316 PVIDEAITGGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGF 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 305 LGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALSAILD 384
Cdd:PRK14726 396 LGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVD 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 385 GNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLYNL--------GFKTESFYGkakapKKIDFV 456
Cdd:PRK14726 476 ANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRRrrpkhlpkGVRTGLFEG-----ANIRFM 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 457 SKRNIFYAISVLIIVCGIGTCVynhTAGnhaFNYSIDFVGGTATTVTFEDGKTpSVEDLESSIEpaiisaasaaDANLKN 536
Cdd:PRK14726 551 GIRRYVFTLSAALSLASLVLFA---TVG---LNLGIDFTGGSLIEVRAKQGNA-DIADIRARLN----------ELNLGE 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 537 LSIshQIVNDQDQVVFKTQSlSTDASQAVNELLTTTYGATDVTY-----ETISATISDEMTSDASWATVIALILMLIYIY 611
Cdd:PRK14726 614 VQV--ERFGSPRDALIRIAS-QDGGENAEQSAVTLVRGELEDDYdfrrvEVVGPAVSGELTMAATLGVLAALAAILIYIW 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 612 FRFrDIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENqhgLRNQEQ--LKELVN 689
Cdd:PRK14726 691 IRF-EWQFAVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVREN---LRRYKKmpLPILID 766
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 2233693744 690 ESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQL 746
Cdd:PRK14726 767 ASINQTLSRTVLTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYIAAPV 823
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
39-442 |
1.26e-118 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 364.93 E-value: 1.26e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 39 INFGLDLAGGVSITYQVAGENG------------------------------------------------------GTPT 64
Cdd:PRK05812 41 MKLGLDLRGGVHFLLEVDMDDAlkkrlesladdlrsllrekkiryggveitfrdaedrdkaiallrklsslteaelKEIT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 65 TQEMDDTVSKLSKRVaSELNTTEASVYKEGSDRITVEIPGATD--EIFETLSTPGNLYFIreyndqgtpnyydpygmgys 142
Cdd:PRK05812 121 EEALEQAIEIIRNRV-NELGVAEPVIQRQGADRIVVELPGVQDtaRAKEILGKTATLEFR-------------------- 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 143 afymlsdGVTVEslqasgdivLSGEDIADAQAGVDNSGtgsEYIVELTLTSEGAKKFATATEAAyaNGWTIGIYYDGAFI 222
Cdd:PRK05812 180 -------LVPVI---------LTGDDITDASASFDQQG---QPVVNITLDSEGAKKFADITKAN--IGKRMAIVLDGEVI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 223 SVPRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIF 302
Cdd:PRK05812 239 SAPVIQSAITGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 303 RILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALSAI 382
Cdd:PRK05812 319 RLFGLIANIALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTI 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 383 LDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLYNLGFKTES 442
Cdd:PRK05812 399 LDSNITTLIAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGRRKRLKK 458
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
42-429 |
2.10e-102 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 320.39 E-value: 2.10e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 42 GLDLAGGVSITYQV----AGENGGTPTTQE------MDDTVSKLSKRVAsELNTTEASVYKEGSDRITVEIPGATD--EI 109
Cdd:TIGR01129 2 GLDLRGGARVLLEVdmstAVVLKLSEAEVNairkdaLEQVITILRNRVN-ALGVSEPVVQRQGKDRIVVELPGVTDtsRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 110 FETLSTPGNLYFiREYNDQGTPNYYDPYGMGYSAFYMLSD-GVTVESLQASGDIVLSGEDIADAQAGVDNSGtgSEYIVE 188
Cdd:TIGR01129 81 KDILGGTATLEF-RLVDDESTSPDDALAGNVPAGSELLDSrSGDPKYYLLKKSPVLTGDHITDATSSVDQRS--GQPVVS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 189 LTLTSEGAKKFATATEAAYanGWTIGIYYDGAFISVPRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRA 268
Cdd:TIGR01129 158 FSLDSEGARIFGDFTQANI--GKRLAIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 269 NVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVD 348
Cdd:TIGR01129 236 RTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 349 ANVLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRG 428
Cdd:TIGR01129 316 ANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRL 395
|
.
gi 2233693744 429 I 429
Cdd:TIGR01129 396 L 396
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
451-753 |
2.82e-98 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 305.82 E-value: 2.82e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 451 KKIDFVSKRNIFYAISVLIIVCGIGTCVYNHtagnhaFNYSIDFVGGTATTVTFEdgKTPSVEDLESSIEPAiisaasaa 530
Cdd:COG0341 7 TNIDFMKKRKIWFAISAVLILASIVSLFTRG------LNLGIDFTGGTLIEVSFE--QPVDLEEVREALEEA-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 531 daNLKNLSIshQIVNDQDQVVFKTQSLSTDASQAVNEL---LTTTYG-ATDVTYETISATISDEMTSDASWATVIALILM 606
Cdd:COG0341 71 --GLGDASV--QTFGSDNDVLIRTPPLDGESAEEVEKVraaLKEAFGdVEIVRVEFVGPTVGKELTRKALLALLVALIGI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 607 LIYIYFRFRdIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHGLRNQEqLKE 686
Cdd:COG0341 147 LIYIAFRFE-WRFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKYRKMT-LAE 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2233693744 687 LVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQLWFSMKKK 753
Cdd:COG0341 225 IINLSINQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIASPLLLWLGKR 291
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
39-756 |
1.31e-86 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 289.60 E-value: 1.31e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 39 INFGLDLAGGVSITYQVAgenggTPTTQEMDDTVSKLSKRVaSELNTTEASVYKEGSDRITVEIPGATDE--IFETLSTP 116
Cdd:PRK13023 45 VSLGLDLSGGSRLILQVQ-----NAGKTDLETTANIMRQRL-EELGYGNPVVEGEGRNQIRVEVPGLYDAqlLKDILTIR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 117 GNLYFiREYNDQGTPN--YYDPYGMGYSAFYMLSDGVTVESLQASGdiVLSGEDIADAQAGVdnSGTGSEYIVELTLTSE 194
Cdd:PRK13023 119 GNLSF-RAMDDTMSPDdaIRGTPPADSEIVYSFDDPPVGYLLKKTP--ILTGHDITDAKASI--SADDGQPVITLTLDDN 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 195 GAKKFATATeaAYANGWTIGIYYDGAFISVPRVQAVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQ 274
Cdd:PRK13023 194 GRRRLADLT--AQGNENSFAIVVDNQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASA 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 275 LGASAIHTSKIAAIIGLALIVLFMIIIFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVF 354
Cdd:PRK13023 272 LGEDYASAAVLAALLAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIY 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 355 ARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLY 434
Cdd:PRK13023 352 ERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWV 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 435 NLGFKTESFYGKAK-APKKIDFVSKRNIFYAISVLIIVCGIGTCVYNhtagNHAFNYSIDFVGGTATTVTFEDGKTpSVE 513
Cdd:PRK13023 432 RTAKPKEVPKRRLKlVPTVTHIPFMRLQFVTLGISVLACAIVVALFV----NIGFNYGIDFRGGSMVELQARNGDA-NLE 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 514 DLESSIepaiisaasaADANLKNLSISHQIVNDQDQVVFKTQSLSTDASQAVNELLTTTYgATDVTY---ETISATISDE 590
Cdd:PRK13023 507 DINERL----------AELNIDSARVLPAKSPRSALVIIGSQEVGDDAEQTVAVKLRGEF-EQDYSFqrvDVVGPTVSEQ 575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 591 MTSDASWATVIALILMLIYIYFRFRdIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDR 670
Cdd:PRK13023 576 LSRAGVLAVILSLIGIFIYVWFRFR-WQLALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDR 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 671 IRENQHGLRNQEqLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQLWFSM 750
Cdd:PRK13023 655 VRENLRRYKSAP-LPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLVQF 733
|
....*.
gi 2233693744 751 KKKSVE 756
Cdd:PRK13023 734 GLKPRE 739
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
210-753 |
2.66e-73 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 260.18 E-value: 2.66e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 210 GWTIGIYYDGAFISVPRVQAVISDgKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAII 289
Cdd:PRK12911 839 GWRMAVVLDGYVVSDPVLNVPLKD-HASVSGKFSHREVHRLATDLKSGAMSFVPEVLSEEVISPELGKSQRTQGIISVCL 917
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 290 GLALIVLFMIIIFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIANGSAVDK 369
Cdd:PRK12911 918 GLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSE 997
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 370 AMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLYNLGFKTE-----SFY 444
Cdd:PRK12911 998 SVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTKFFFMIWMNKTQETQlhmmnKFI 1077
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 445 GkakapKKIDFVSKRNIFYAISVLIIVCGigtCVynhTAGNHAFN--YSIDFVGGTATTVTFEDGKTPSVEDLESSI-EP 521
Cdd:PRK12911 1078 G-----IKHDFLKECKRLWVVSGSVLVLG---CV---ALGFGAWNsvLGMDFKGGYALTLDPSDVCEYDVEQMRSKLrKK 1146
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 522 AIISAASAADANLKNLSISHQI-VNDQDQVVFKTQSLSTDASQAVNELLTTTYG-----ATDVTYET----------ISA 585
Cdd:PRK12911 1147 FQQIGLSSRDFRIRTFDSSEKIkIYFSQNALDRVEAIEGAGSEQSDHHLALVLGvlsdtGSDTSSEVfdatqnfwfkVSG 1226
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 586 TISDEMTSDASWATVIALILMLIYIYFRFrDIRFGASAIIALAHD-----AIMVIMCYAFTRLEVGSTFIAVVLTIIGYS 660
Cdd:PRK12911 1227 QLSNKMRTQAVIALFGALGIILLYVSLRF-EWRYAFSAICALIHDllatcAVLVALHFFLQKIQIDLQAIGALMTVLGYS 1305
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 661 INDTIVTFDRIRENQhglrnQEQLKE----LVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGT 736
Cdd:PRK12911 1306 LNNTLIIFDRIREDR-----QEKLFTpmpiLINDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAFIMTIGILLGT 1380
|
570
....*....|....*..
gi 2233693744 737 YSSICIASQLWFSMKKK 753
Cdd:PRK12911 1381 LSSLYIAPPLLLFMVRK 1397
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
488-743 |
4.78e-54 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 186.71 E-value: 4.78e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 488 FNYSIDFVGGTATTVTFEdgKTPSVEDLESSIEPAIISaasaadanlknlSISHQIVNDQDQVVFKTQSLSTDASQAVNE 567
Cdd:TIGR00966 2 FNFGIDFTGGTVIETRLE--QAADVAEVRDVLEKAGIE------------GVVIQEFGSSHTIMIRIPTLDTEQSEELRE 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 568 LLTTTYGATDVTYETISATI-----SDEMTSDASWATVIALILMLIYIYFRFRdIRFGASAIIALAHDAIMVIMCYAFTR 642
Cdd:TIGR00966 68 ALEEALKNVDPDAEIRSIDAvgpsvGGELARKAVLALLAALVLILIYITVRFE-WRFALGAIVALVHDVIITVGVYSLFG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 643 LEVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHGLRNQEqLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIK 722
Cdd:TIGR00966 147 IEVNLTTVAALLTIIGYSINDTVVVFDRIRENLRKYTRKT-FTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIK 225
|
250 260
....*....|....*....|.
gi 2233693744 723 TFALPLMVGVVSGTYSSICIA 743
Cdd:TIGR00966 226 DFSLALLVGVIVGTYSSIFIA 246
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
82-434 |
2.18e-52 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 192.21 E-value: 2.18e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 82 ELNTTEASVYKEGSDRITVEIPGATDE------IFETLSTpgnlyfireyndqgtpnyydpygmgysAFYMLSDGVTVES 155
Cdd:PRK12933 245 ELGITEALVQRQGEHRIRIELPGVQDPaaaknvIGATASL---------------------------AFYEVKESGSVNA 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 156 L---QASGDIV-------LSGEDIADAQAGVDNSGTgSEyiVELTLTSEGAKKF------------ATATeAAYANGWTI 213
Cdd:PRK12933 298 KvlkDKNGRPVyvarrpvLGGEHIVDARASLGEMGM-AE--VNISLDRAGGKKMsdfsrdnigkpmATSY-SEYSRDEQG 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 214 GIYYDGAFISVPRVQAVISDgKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLAL 293
Cdd:PRK12933 374 KTKQSEEVISVATIQSQLGD-RFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGI 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 294 IVLFMIIIFRILGVAASMALgfyCCFMVILLSAFDI----TLTLPGIAGIILSIGMAVDANVLVFARIREEIANGSAVDK 369
Cdd:PRK12933 453 TLLFMALWYRRLGWVANVAL---IANMVCLFGLLALipgaVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQ 529
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2233693744 370 AMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLY 434
Cdd:PRK12933 530 AIDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALINLVY 594
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
575-753 |
2.28e-51 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 177.41 E-value: 2.28e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 575 ATDVTYETISATISDEMTSDASWATVIALILMLIYIYFRFRDiRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVL 654
Cdd:pfam02355 13 AEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEW-RFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 655 TIIGYSINDTIVTFDRIRENqhgLRNQ--EQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGV 732
Cdd:pfam02355 92 TIIGYSVNDTVVVFDRVREN---LRKKtrATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGV 168
|
170 180
....*....|....*....|.
gi 2233693744 733 VSGTYSSICIASQLWFSMKKK 753
Cdd:pfam02355 169 IVGTYSSIFIASPILLDLGER 189
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
269-423 |
5.93e-38 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 140.08 E-value: 5.93e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 269 NVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRILGVAASMALGFYC-CFMVILLSAFDITLTLPGIAGIILSIGMAV 347
Cdd:TIGR00916 35 GTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDvILILGVLSLFGATLTLPGIAGLLTIIGYSV 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2233693744 348 DANVLVFARIREEI--ANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTAL 423
Cdd:TIGR00916 115 DDTVVIFDRIREELrkYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
579-740 |
5.56e-37 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 137.00 E-value: 5.56e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 579 TYETISATISDEMTSDASWATVIALILMLIYIYFRFRdIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIG 658
Cdd:TIGR00916 33 VVGTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYE-WRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIG 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 659 YSINDTIVTFDRIRENQHGLRNqEQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYS 738
Cdd:TIGR00916 112 YSVDDTVVIFDRIREELRKYKG-RTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYS 190
|
..
gi 2233693744 739 SI 740
Cdd:TIGR00916 191 SI 192
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
33-427 |
1.14e-32 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 131.15 E-value: 1.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 33 DGSMHDINFGLDLAGGVSITYQVAGENggtpTTQEMDDTVSKLSKRVaSELNTTEASVYKEGSDRITVEIPGA-TDEIFE 111
Cdd:PRK08343 34 PGGFTNLQYGLDLSGGSWIQLKLEGPV----TQETMDLVVEILESRL-NALGLKDIKVYPVGDQYIVVEVPGVdADTAKE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 112 TLSTPGNLYfIReyndqgtpnyydpygmgysAFYMLSDGVTveslqasgdiVLSGEDIADAQAgVDNSGTGSEYIVELTL 191
Cdd:PRK08343 109 IIEKQGVFE-AR-------------------IQTPGNNNET----------VLTGDDIESVGS-PSQDPSGGAWGVPFTL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 192 TSEGAKKFAT-ATEAAYAN---GWTIGIYYDGAFISVPRVQAVISDGKAS----------ITGMSSYEAAENLASTIRIG 257
Cdd:PRK08343 158 SEDGAEKFAEvAKGKGATDdpsGHPLDMYLDGELIYAAPLSPDLASGLASgpvvitvgstGTTEEAKEEAKELYIHLRSG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 258 GLDVSLTELRANVVGAQLGASAIHTSKIAAIigLALIVLFMIIIFR---------ILGVAAS---MALGFyccfmvilLS 325
Cdd:PRK08343 238 ALPVKLDIEGSGSVSPSLGEQFKKGSLIAGL--LALLAVALVVFLRyreprialpMVITSLSeviIILGF--------AA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 326 AFDITLTLPGIAGIILSIGMAVDANVLvfarIREEIANGSAVDKAM--KAGYSKALSAILDGNITTLIAAGVLGLRGTGT 403
Cdd:PRK08343 308 LIGWQLDLASIAGIIAVIGTGVDDLII----ITDEVLHEGKVPSRKvfLSRIKRAFFIIFAAAATTIAAMSPLAVMGLGD 383
|
410 420
....*....|....*....|....
gi 2233693744 404 VRGFAITLALGIVIsmftALFVTR 427
Cdd:PRK08343 384 LKGFAITTILGVLI----GVLITR 403
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
451-746 |
7.56e-30 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 119.96 E-value: 7.56e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 451 KKIDFVSKRNIFYAISVLIIVCGIGTCvynhtaGNHAFNYSIDFVGGTATTVTfedgktpsvedLESSIEPAIISAASAA 530
Cdd:PRK13021 2 KNINLTKWRYISSAISIVLMLLSLTII------GVKGFNWGLDFTGGVVTEVQ-----------LDRKITSSELQPLLNA 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 531 DANlKNLSISHQIVNDQDQVVFKTQSLSTDASQAVNELLTTTYGATDVTYETISATISDEMTSDASWATVIALILMLIYI 610
Cdd:PRK13021 65 AYQ-QEVSVISASEPGRWVLRYAPADTAQSNVDIQQALAPLGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 611 YFRFrDIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENqhgLRNQEQL--KELV 688
Cdd:PRK13021 144 SYRF-EWRLASGALFALVHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIREL---LIAKPKLaiQEIN 219
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2233693744 689 NESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQL 746
Cdd:PRK13021 220 NQAIVATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSL 277
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
270-714 |
3.87e-20 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 95.70 E-value: 3.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 270 VVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFR-ILGVAASMAlgfyCCFMVI-----LLSAFDITLTLPGIAGIILSI 343
Cdd:COG1033 207 VLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRsLRGVLLPLL----VVLLAViwtlgLMGLLGIPLSPLTILVPPLLL 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 344 GMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTAL 423
Cdd:COG1033 283 AIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSL 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 424 FVtrgISALLYNLGFKTESFYGKAKAPKKIDFVSK--------RNIFYAISVLIIVCGI----GTCVYNHTAG----NHA 487
Cdd:COG1033 363 TL---LPALLSLLPRPKPKTRRLKKPPELGRLLAKlarfvlrrPKVILVVALVLAVVSLygisRLKVEYDFEDylpeDSP 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 488 FNYSIDFV----GGTAT-TVTFEDGKTPSVEDLE---------------------SSI---------------------- 519
Cdd:COG1033 440 IRQDLDFIeenfGGSDPlEVVVDTGEPDGLKDPEvlkeidrlqdyleslpevgkvLSLadlvkelnqalnegdpkyyalp 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 520 EPAIISAASAADANLKNLSISHQIVNDQDQ---VVFKTQSLSTDAS----QAVNELLTTTYGATDVTYET-----ISATI 587
Cdd:COG1033 520 ESRELLAQLLLLLSSPPGDDLSRFVDEDYSaarVTVRLKDLDSEEIkalvEEVRAFLAENFPPDGVEVTLtgsavLFAAI 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 588 SDEMTSDASWATVIALILMLIYIYFRFRDIRFGASAIIALahdAIMVIMCYAFTRLEVGSTFI--AVVLTI-IGYSINDT 664
Cdd:COG1033 600 NESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPN---LLPILLTFGLMGLLGIPLNIatAVVASIaLGIGVDYT 676
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 2233693744 665 IVTFDRIRENqhgLRNQEQLKELVNESVNQTLTRSLFTSITTFIMVLCLY 714
Cdd:COG1033 677 IHFLSRYREE---RRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLL 723
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
233-423 |
1.38e-15 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 80.97 E-value: 1.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 233 DGKASITGMSSYEAAENLASTIRIGGLDVSLTElrANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFR--------- 303
Cdd:COG2409 123 DGDAGDEAAEAVDALRDAVAAAPAPGLTVYVTG--PAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRslvaallpl 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 304 ---ILGVAASMALgfyccfMVILLSAFDITLTLPGIAgIILSIGMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALS 380
Cdd:COG2409 201 ltaGLAVGVALGL------LALLAAFTDVSSFAPNLL-TMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGR 273
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2233693744 381 AILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTAL 423
Cdd:COG2409 274 AVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAAL 316
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
226-433 |
1.25e-14 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 75.79 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 226 RVQAVISDGKASITGMSSYEAAENLASTIRIG-GLDVSLTELRAnvVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFR- 303
Cdd:pfam03176 88 YVVVTLEGDPGTTEADESVAAVRDAVEQAPPPeGLKAYLTGPAA--TVADLRDAGDRDLGLIEAVTLVVIFIILLIVYRs 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 304 -------ILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILsIGMAVDANVLVFARIREEIANGSAVDKAMKAGYS 376
Cdd:pfam03176 166 vvaallpLLTVGLSLGAAQGLVAILAHILGIGLSTFALNLLVVLL-IAVGTDYALFLVSRYREELRAGEDREEAVIRAVR 244
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2233693744 377 KALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALL 433
Cdd:pfam03176 245 GTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALL 301
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
245-441 |
8.75e-13 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 71.81 E-value: 8.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 245 EAAENLASTIRIGGLDVSLTELraNVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRilgvaaSMALGFyCCFMVILL 324
Cdd:COG1033 571 EVRAFLAENFPPDGVEVTLTGS--AVLFAAINESVIESQIRSLLLALLLIFLLLLLAFR------SLRLGL-ISLIPNLL 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 325 SAFdITLTLPGIAGIIL----------SIGMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAG 394
Cdd:COG1033 642 PIL-LTFGLMGLLGIPLniatavvasiALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFG 720
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2233693744 395 VLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLYNLGFKTE 441
Cdd:COG1033 721 VLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRIAKKR 767
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
218-439 |
3.25e-11 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 64.69 E-value: 3.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 218 DGAFISVPRVQAVISDGKASITGMSSYEAAENLASTIR--IGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIV 295
Cdd:COG0341 68 EEAGLGDASVQTFGSDNDVLIRTPPLDGESAEEVEKVRaaLKEAFGDVEIVRVEFVGPTVGKELTRKALLALLVALIGIL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 296 LFMIIIFRI-LGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIAN------GSAVD 368
Cdd:COG0341 148 IYIAFRFEWrFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAALLTIIGYSLNDTVVVFDRIRENLRKyrkmtlAEIIN 227
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2233693744 369 KAMkagySKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTrgiSALLYNLGFK 439
Cdd:COG0341 228 LSI----NQTLSRTINTSLTTLLVVLALLFFGGETLRDFALALLIGIIVGTYSSIFIA---SPLLLWLGKR 291
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
258-435 |
4.34e-11 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 62.62 E-value: 4.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 258 GLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFR-ILGVAASMALGFYCCFMVILLSAFDITLTLPGI 336
Cdd:pfam02355 8 NVGPDAEIISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 337 AGIILSIGMAVDANVLVFARIREEI--ANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALG 414
Cdd:pfam02355 88 AALLTIIGYSVNDTVVVFDRVRENLrkKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVG 167
|
170 180
....*....|....*....|.
gi 2233693744 415 IVISMFTALFVTRGISALLYN 435
Cdd:pfam02355 168 VIVGTYSSIFIASPILLDLGE 188
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
229-467 |
4.80e-11 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 66.72 E-value: 4.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 229 AVISDGKASITGMSSYEAAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRILGVA 308
Cdd:NF037998 393 GSNTNSNQLIVATSTETIARTIEALINQTTSGFTFKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIYLLFAYRLLGLF 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 309 ASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEI-ANGSAVDKAMKAGYSKALSAILDGNI 387
Cdd:NF037998 473 AIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLyKNKRSIEESFKIANKETIGIIVDALV 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 388 TTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRgisaLLYNLGFKTESFYGKAK-APKKIDFVSKRNIFYAIS 466
Cdd:NF037998 553 VLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVAR----LMIWLTIKLQWFKKYPWlLPLDTDFANQGVAILNYK 628
|
.
gi 2233693744 467 V 467
Cdd:NF037998 629 I 629
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
582-740 |
2.40e-09 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 59.99 E-value: 2.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 582 TISATISDEMTSDASWATVIALILMLIYIYFRFRdiRFGASAIIALahdaimviMCYAFTRLEVGSTFIAV--------- 652
Cdd:TIGR01129 237 TIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYR--LFGLIAAIAL--------VINIVLILAILSAFGATltlpgiagl 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 653 VLTIiGYSINDTIVTFDRIRENqhgLRNQEQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGV 732
Cdd:TIGR01129 307 ILTI-GMAVDANVLIYERIKEE---LRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGI 382
|
....*...
gi 2233693744 733 VSGTYSSI 740
Cdd:TIGR01129 383 IASLFTAL 390
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
581-740 |
4.31e-09 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 59.36 E-value: 4.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 581 ETISATISDEMTSDASWATVIALILMLIYIYFRFRdiRFGASAIIALAhdaIMVIMCYAFTRLeVGSTF----IA-VVLT 655
Cdd:COG0342 259 RTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYR--LPGLVANIALA---LNVVLLLGVLSL-LGATLtlpgIAgIILT 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 656 IiGYSINDTIVTFDRIREnqhGLRNQEQLKELVNESVNqtltRSLFT----SITTFIMVLCLYVVGVQDIKTFALPLMVG 731
Cdd:COG0342 333 I-GMAVDANVLIFERIRE---ELRAGRSLRAAIEAGFK----RAFSTildaNVTTLIAAVVLFVLGTGPVKGFAVTLILG 404
|
....*....
gi 2233693744 732 VVSGTYSSI 740
Cdd:COG0342 405 ILISMFTAV 413
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
289-428 |
7.30e-09 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 59.10 E-value: 7.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 289 IGLALIVLFMIIIFR----ILGVAASMALGFYCcfMVILLSAFDITLTLPGIAGIILSIGMAVDANvLVFARIREEiang 364
Cdd:COG4258 647 LALLLILLLLLLRLRslrrALRVLLPPLLAVLL--TLAILGLLGIPLNLFHLIALLLVLGIGIDYA-LFFTEGLLD---- 719
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2233693744 365 savdkamKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRG 428
Cdd:COG4258 720 -------KGELARTLLSILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLAPLLAPR 776
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
217-425 |
1.51e-08 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 56.13 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 217 YDGAFISVPRVQAVISDGKASI-TGMSSYEAAENLASTIR--IGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLAL 293
Cdd:TIGR00966 31 LEKAGIEGVVIQEFGSSHTIMIrIPTLDTEQSEELREALEeaLKNVDPDAEIRSIDAVGPSVGGELARKAVLALLAALVL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 294 IVLFMIIIF-RILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEI--ANGSAVDKA 370
Cdd:TIGR00966 111 ILIYITVRFeWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTIIGYSINDTVVVFDRIRENLrkYTRKTFTEV 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2233693744 371 MKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFV 425
Cdd:TIGR00966 191 INLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTYSSIFI 245
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
549-733 |
2.39e-08 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 57.56 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 549 QVVFKTQSLST--DASQAVNEL--LTTTYGATDVTYET-----ISATISDEMTSDASWATVIALILMLIYIYFRFRDIRF 619
Cdd:COG1033 165 VVTLDPDPLSSdlDRKEVVAEIraIIAKYEDPGVEVYLtgfpvLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRG 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 620 --------GASAIIALAhdaimvIMCYAFTRLEVGSTFIAVVLTIIGysINDTIVTFDRIRENqhgLRNQEQLKELVNES 691
Cdd:COG1033 245 vllpllvvLLAVIWTLG------LMGLLGIPLSPLTILVPPLLLAIG--IDYGIHLLNRYREE---RRKGLDKREALREA 313
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2233693744 692 VNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVV 733
Cdd:COG1033 314 LRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVL 355
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
257-426 |
4.75e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 56.77 E-value: 4.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 257 GGLDVSLTELraNVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFR--ILGVAASMALGFYCCFMVILLSAFDITLTLP 334
Cdd:TIGR00921 545 PGVKVGVTGL--PVAFAEMHELVNEGMRRMTIAGAILVLMILLAVFRnpIKAVFPLIAIGSGILWAIGLMGLRGIPSFLA 622
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 335 GIAGIILSIGMAVDANVLVFARIREEIANGSAVDkAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALG 414
Cdd:TIGR00921 623 MATTISIILGLGMDYSIHLAERYFEERKEHGPKE-AITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIG 701
|
170
....*....|..
gi 2233693744 415 IVISMFTALFVT 426
Cdd:TIGR00921 702 VLSSLTAALVVF 713
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
242-426 |
8.19e-08 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 55.77 E-value: 8.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 242 SSYEAAENLASTIRIGGLDVSLTELRanvvGAQLG------------ASAIHTSKIAAIIGLALIVLFMIIIFR----IL 305
Cdd:TIGR03480 222 SSLEPAEKAINAIRAAAKDLRLDEDH----GVTVRltgevalsdeelATVSEGATVAGLLSFVLVLVLLWLALRsprlVF 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 306 GVAASMALGfyccfmVILLSAFDI----TLTLPGIAGIILSIGMAVDANVLVFARIREEIANGSAVDKAMKAGYSKALSA 381
Cdd:TIGR03480 298 AVLVTLIVG------LILTAAFATlavgHLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAA 371
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2233693744 382 ILDGNITTliAAGVLGLRGTgTVRGFAitlALGIV--ISMFTALFVT 426
Cdd:TIGR03480 372 LLLAALAT--AAGFFAFLPT-DYKGVS---ELGIIagTGMFIALFVT 412
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
239-433 |
1.05e-07 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 54.09 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 239 TGMSSYEAAENLAStiriggLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLALIVLFMIIIFRI-LGVAASMALGFYC 317
Cdd:PRK13021 90 TAQSNVDIQQALAP------LGTEVQVLNSSIVGPQVGQELAEQGGLALLVAMLCILGYLSYRFEWrLASGALFALVHDV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 318 CFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIRE------EIANGSAVDKAMKAGYSKALsaILDGniTTLI 391
Cdd:PRK13021 164 IFVLAFFALTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRElliakpKLAIQEINNQAIVATFSRTM--VTSG--TTLM 239
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2233693744 392 AAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALL 433
Cdd:PRK13021 240 TVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPELL 281
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
533-757 |
1.39e-07 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 55.17 E-value: 1.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 533 NLKNLSISHQIVNDQDQVVFKTQSlSTDASQAVNELLTTTYGA--TDVTYETISATISDEMTSDASWATVIALILMLIYI 610
Cdd:NF037998 384 NGTKTGAGAGSNTNSNQLIVATST-ETIARTIEALINQTTSGFtfKVNGISEFNPVVTLLMLIASIIFLLILAIAIMIYL 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 611 YFRFRdiRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHglRNQEQLKELVNE 690
Cdd:NF037998 463 LFAYR--LLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLY--KNKRSIEESFKI 538
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2233693744 691 SVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQL-WFSMKKKSVEK 757
Cdd:NF037998 539 ANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMiWLTIKLQWFKK 606
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
581-753 |
1.77e-07 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 54.46 E-value: 1.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 581 ETISATISDEMTSDASWATVIALILMLIY--IYFRFrdirFGASAIIALAHDAIMVIMCYAFtrleVGSTF----IA-VV 653
Cdd:PRK05812 285 RTIGPSLGADSIRAGLIAGLIGLALVLLFmiLYYRL----FGLIANIALVANLVLILAVLSL----LGATLtlpgIAgIV 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 654 LTIiGYSINDTIVTFDRIRENqhgLRNQEQLKELVNESVNQTLtRSLFTS-ITTFIMVLCLYVVGVQDIKTFALPLMVGV 732
Cdd:PRK05812 357 LTI-GMAVDANVLIFERIREE---LREGRSLRSAIEAGFKRAF-STILDSnITTLIAAIILYALGTGPVKGFAVTLGIGI 431
|
170 180
....*....|....*....|....
gi 2233693744 733 VSGTYSSICIA---SQLWFSMKKK 753
Cdd:PRK05812 432 LTSMFTAITVTralVNLLYGRRKR 455
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
275-734 |
3.10e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.07 E-value: 3.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 275 LGASAIHTSKIAAIIGLALIVLF------MIIIFRILGVAASMALGFyccfMVILLSAFDITLTLPGIagiiLSIGMAVD 348
Cdd:TIGR00921 191 FGKDMGTTMAISGILVVLVLLLDfkrwwrPLLPLVIILFGVAWVLGI----MGWLGIPLYATTLLAVP----MLIGVGID 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 349 ANVLVFARIREEIANGSAVDKAMKAGYSKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTrg 428
Cdd:TIGR00921 263 YGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVL-- 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 429 iSALLYNL-------GFKTESFYGKA----KAPKKIDFVSKRNIFYAISVLIIVCGIG---------------------- 475
Cdd:TIGR00921 341 -PALLQSIdigrekvKKEIIAIGGKSseieEELSKVLSITVRHPVPALVAALIITGLGlygaagikpevniekfipqdlp 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 476 -----TCVYNHTAGNHAFNYSIDFVGGT--ATTVTFEDG---------------KTPSVEDLESSIEpAIISAASAADAN 533
Cdd:TIGR00921 420 slqarKVIESHMGGSHDFATILVKADDVrdPELVRFMDElsrdikatgvaarvfGAPSIIDLVKEVE-GLPAPERSALEP 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 534 LKNLSISHQIVNDQDQVVFKTQSLSTDASQAVNELLT-----------TTYGATDVTYetISATISDEMTSDASWATVIA 602
Cdd:TIGR00921 499 IPEDEEGGYISGGQIKVAVIQVQLKQGEPKVQGRKILrdvqhehpppgVKVGVTGLPV--AFAEMHELVNEGMRRMTIAG 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 603 LILMLIYIYFRFRDIRFGASAIIA-----LAHDAIMVIMCYAFTRlevgsTFIAVVLTIIGYSINDTIVTFDRIRENqhg 677
Cdd:TIGR00921 577 AILVLMILLAVFRNPIKAVFPLIAigsgiLWAIGLMGLRGIPSFL-----AMATTISIILGLGMDYSIHLAERYFEE--- 648
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 2233693744 678 lRNQEQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVS 734
Cdd:TIGR00921 649 -RKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLS 704
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
221-433 |
6.57e-07 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 53.05 E-value: 6.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 221 FISVPRVQAVISDGKASITGMSSY-EAAENLA----STIRIGGLDVSLTELRaNVVGAQLGasaihtskIAAIIGLALIV 295
Cdd:TIGR00833 688 LLVYGDGSPAGDQGAQEFNAIRTVaEEAIQRAdlepAKVELAGVSAVNRDLR-DLVNSDLG--------LISIITLAIVF 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 296 LFMIIIFRILGVA----ASMALGFYCCF-----MVILLSAFDITLTLPGIAGIILsIGMAVDANVLVFARIREEIANGsa 366
Cdd:TIGR00833 759 MILALLLRAPVAPivliGSVALSYLWALglsvlAFQHILGAELHWSVLAGVFVLL-VALGVDYNMLLVSRIKEESPAG-- 835
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2233693744 367 vdkaMKAGYSKALSA----ILDGNITTliAAGVLGLRGTG--TVRGFAITLALGIVISMFTALFVTRGISALL 433
Cdd:TIGR00833 836 ----NRTGIIRALGStggvITAAGLVF--AGTMAALASAQltAIAQFGFTVGVGILLDTFIVRSVTVPALTLL 902
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
491-731 |
1.03e-06 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 51.09 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 491 SIDFVGGTATTVTFEDGKTPSVEDlessiepaiisaasaadaNLKNLSISHQIVNDQDQVVFKTQSLSTDASQAVNELLT 570
Cdd:PRK08578 45 GIDFTGGTEITIQTNDASPDELES------------------ALSGEPGVDVRKGSGNGYIITFGSGDDTDVDKLADAVK 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 571 TTY-----GATDVTYETISATISDEMTSDASWATVIALILMLIYIYFRFRDIRFGASAIIALAHDAIMVIMCYAFTRLEV 645
Cdd:PRK08578 107 EFFnvdsiSELNYSEKQIGPTFGSQFQEQALKAVGFAFIGMAVVVFLIFRTPVPSLAVILSAFSDIIIALALMNLFGIEL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 646 GSTFIAVVLTIIGYSINDTIVTfdrireNQHGLRNQEQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFA 725
Cdd:PRK08578 187 SLATVAALLMLIGYSVDSDILL------TTRVLKRRGTFDESIKRAMRTGITMTLTTIAAMAVLYIVSTIPQAEVLANIA 260
|
....*.
gi 2233693744 726 LPLMVG 731
Cdd:PRK08578 261 AVLIFG 266
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
226-459 |
3.21e-06 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 50.74 E-value: 3.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 226 RVQAVISDGKASITGMSSYEAAEN-LASTIRIGGLDVSLTELRANVVG--AQLGASAIHTSKIAAIIGLALIVLF----- 297
Cdd:TIGR00833 119 IIIVNLAGEKGQKEAQEAINAVRRiVEQTNAPDGLTVHVTGPLATIADilESGDKDMNRITATTGIIVLIILLLVyrspi 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 298 -MIIIFRILGVAASMALGFyccfMVILLSAFDITLTLPGIAGII-LSIGMAVDANVLVFARIREEIANGSAVDKAMKAGY 375
Cdd:TIGR00833 199 tMLVPLVSVGFSVVVAQGI----VSLLGIPGLIGVNAQTTVLLTaLVIGAGTDYAVFLTGRYHEERRKGESLEEAAAEAL 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 376 SKALSAILDGNITTLIAAGVLGLRGTGTVRGFAITLALGIVISMFTALFVTRGISALLYNLGFKtesfygKAKAPKKIDF 455
Cdd:TIGR00833 275 RGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVALLNAVTLTPALLTLEGREGLM------KPGRKSKIRF 348
|
....
gi 2233693744 456 VSKR 459
Cdd:TIGR00833 349 IWRR 352
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
278-433 |
7.16e-05 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 46.52 E-value: 7.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 278 SAIHTSKIAAIIGLALIVLFMIIIFR------ILGVAASMALGFYCCFMVillsAFDITLTLPGIAGIILSIGMAVDANV 351
Cdd:pfam00873 328 ASIEEVVKTLLEAIVLVILVMFLFLQnwratlIPAIAIPLSLLGTFAVMK----AFGFSINTLTLGGLVLAIGLVVDDAI 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 352 LVFARIREEIA-NGSAVDKAMKAGYSKALSAILDGNITtLIAAGVLGLRGTGTV----RGFAITLALGIVISMFTALFVT 426
Cdd:pfam00873 404 VVVENIERVLEeNGLKPLEAAYKSMGEIGGALVAIALV-LSAVFLPILFLGGLTgrifRQFAITIVLAILLSVLVALTLT 482
|
....*..
gi 2233693744 427 RGISALL 433
Cdd:pfam00873 483 PALCATL 489
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
278-426 |
3.19e-04 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 44.32 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 278 SAIHTSKIAAIIGLALIVLFMIIIFR--------ILGVAASMALGFyccfmvILLSAFDITL---TLpgiAGIILSIGMA 346
Cdd:COG0841 328 ASIEEVVKTLLEAILLVVLVVFLFLRswratlipAVAIPVSLIGTF------AVMYLLGFSLnilTL---FALVLAIGIV 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 347 VDA------NVlvfARIREEiaNGSAVDKAMKAgySKALS-AILDGNITTLIA----------AGVLglrgtgtVRGFAI 409
Cdd:COG0841 399 VDDaivvveNI---ERHMEE--GLSPLEAAIKG--AREVAgAVIASTLTLVAVflplafmggiTGQL-------FRQFAL 464
|
170
....*....|....*..
gi 2233693744 410 TLALGIVISMFTALFVT 426
Cdd:COG0841 465 TVAIALLISLFVALTLT 481
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
285-417 |
1.06e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.45 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 285 IAAIIGLALIVLFmiIIFR--------ILGVAASM--ALG-----FYCCFMVILLSAFDITLTLPGIAGIILsIGMAVDA 349
Cdd:COG2409 523 IPVVLGLIFLLLL--LLFRsvvaplkaVLTNLLSLgaALGvlvlvFQHGWLLLGFTPGPLDSFVPLLLFVIL-FGLGMDY 599
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2233693744 350 NVLVFARIREEIANGSAVDKAMKAGYSK------ALSAILdgnITTLIAAGVLGLRgtgTVRGFAITLALGIVI 417
Cdd:COG2409 600 EVFLVSRIREEYDRGGGTREAVIRGLARtgrvitSAALIM---AAVFAAFATSPLV---FLKQIGFGLAVGVLL 667
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
256-425 |
5.97e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.22 E-value: 5.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 256 IGGLDVSLTELRANVVGAQL-----GASAIHTSKIA-------AIIGLALIVLFMIIIFR----ILGVAASMALGFyCCF 319
Cdd:COG4258 212 VAALRAAFAALNAAFPGAQLlltgaGLFAVAAAQQIkhdistiGLISLLGILLLLLLVFRslrpLLLGLLPVAVGA-LAG 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2233693744 320 MVILLSAFD----ITLtlpGIaGIILsIGMAVDANVLVFARIReeiangSAVDKAMKAGYSKALSAILDGNITTLIAAGV 395
Cdd:COG4258 291 LAAVSLVFGsvhgITL---GF-GSSL-IGVAVDYSLHYLTHRR------AAGEWDPRAALRRIWPTLLLGLLTTVLGYLA 359
|
170 180 190
....*....|....*....|....*....|....*.
gi 2233693744 396 L------GLRGTGTvrgFAITlalGIVISMFTALFV 425
Cdd:COG4258 360 LlfspfpGLRQLGV---FAAA---GLLAAALTTLLW 389
|
|
| |
