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Conserved domains on  [gi|2255860072|ref|WP_251865620|]
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tautomerase family protein [Enterococcus malodoratus]

Protein Classification

4-oxalocrotonate tautomerase family protein( domain architecture ID 10004965)

4-oxalocrotonate tautomerase family protein similar to 4-oxalocrotonate tautomerase, also called 2-hydroxymuconate tautomerase, which catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 2-51 9.29e-13

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 441545  Cd Length: 58  Bit Score: 56.31  E-value: 9.29e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 2255860072  2 PHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:COG1942    1 PIINIKLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPPENW 50
 
Name Accession Description Interval E-value
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 2-51 9.29e-13

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 56.31  E-value: 9.29e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 2255860072  2 PHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:COG1942    1 PIINIKLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPPENW 50
PRK01271 PRK01271
tautomerase PptA;
1-60 5.67e-10

tautomerase PptA;


Pssm-ID: 179269  Cd Length: 76  Bit Score: 49.77  E-value: 5.67e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2255860072  1 MPHLSVRLYPGR-TKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW-DDVIDDEIA 60
Cdd:PRK01271   1 MPHIDIKCFPRElDEEQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWqAEVWDAEIA 62
Tautomerase pfam01361
Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that ...
 2-51 1.83e-05

Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that catalyzes the ketonization of 2-hydroxymuconate to 2-oxo-3-hexenedioate.


Pssm-ID: 396090  Cd Length: 60  Bit Score: 38.04  E-value: 1.83e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 2255860072  2 PHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:pfam01361  1 PFVNIKLFEGRTDEQKKELIERVTDALVEVLGAPRSAIVVIIEEVPPENW 50
 
Name Accession Description Interval E-value
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 2-51 9.29e-13

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 56.31  E-value: 9.29e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 2255860072  2 PHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:COG1942    1 PIINIKLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPPENW 50
PRK01271 PRK01271
tautomerase PptA;
1-60 5.67e-10

tautomerase PptA;


Pssm-ID: 179269  Cd Length: 76  Bit Score: 49.77  E-value: 5.67e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2255860072  1 MPHLSVRLYPGR-TKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW-DDVIDDEIA 60
Cdd:PRK01271   1 MPHIDIKCFPRElDEEQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWqAEVWDAEIA 62
PRK00745 PRK00745
4-oxalocrotonate tautomerase; Provisional
 1-51 2.85e-09

4-oxalocrotonate tautomerase; Provisional


Pssm-ID: 179107  Cd Length: 62  Bit Score: 47.79  E-value: 2.85e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 2255860072  1 MPHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:PRK00745   1 MPTFHIELFEGRTVEQKRKLVEEITRVTVETLGCPPESVDIIITDVKRENW 51
Tautomerase pfam01361
Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that ...
 2-51 1.83e-05

Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that catalyzes the ketonization of 2-hydroxymuconate to 2-oxo-3-hexenedioate.


Pssm-ID: 396090  Cd Length: 60  Bit Score: 38.04  E-value: 1.83e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 2255860072  2 PHLSVRLYPGRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:pfam01361  1 PFVNIKLFEGRTDEQKKELIERVTDALVEVLGAPRSAIVVIIEEVPPENW 50
Tautomerase_2 pfam14552
Tautomerase enzyme;
11-51 2.73e-03

Tautomerase enzyme;


Pssm-ID: 434035  Cd Length: 82  Bit Score: 32.92  E-value: 2.73e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 2255860072 11 GRTKEVKQDFAEKLQDLVVKELGCEPNVVSVSFKEIEKEKW 51
Cdd:pfam14552 39 GRSVEQKKALYRALAERLAAKLGIRPEDVFIVLVENPKENW 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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