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Conserved domains on  [gi|2273758829|ref|WP_254803772|]
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gamma-glutamyltransferase [Aeromonas salmonicida]

Protein Classification

gamma-glutamyltransferase family protein( domain architecture ID 10001375)

gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond

CATH:  3.60.20.40
Gene Ontology:  GO:0016787
SCOP:  4000420

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
1-533 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


:

Pssm-ID: 440174  Cd Length: 507  Bit Score: 627.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWD--GSKVAAVDGRETAPAAATDQLFMK 78
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDakDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  79 DGKPMAfydgVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKD-PYLAKDPDARAYF 157
Cdd:COG0405    81 AGDEIP----VRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAaERLARDPGAAAIF 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 yLPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQHptnPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:COG0405   157 -LPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAA---GGLLTLEDLAAYRAEWREPLSGTYRGY 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGtIALGQIFGMLESRDMAALKPvttpegqlaASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLD 317
Cdd:COG0405   233 TVYSMPPPSQG-IALLQILNILEGFDLAALGP---------DSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLS 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 318 KGYLAERSKLVG-ERSMGIAQPGMPPlalargkdaTPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMV--NGYLLNN 394
Cdd:COG0405   303 PAYAAERAALIDpDRATPSPRPGDPT---------GPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNN 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 395 QLTDFSFTSVDaaglpvANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAINL 474
Cdd:COG0405   374 RGDDFSLDPGH------PNALAPGKRPRSTMSPTIVLKD--GKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDA 445
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2273758829 475 PNFGSRNGPTELEL-GRTPESVVEGLKARGHEVVLSEQTSG-LQGVERNAGG-WFGAADPRR 533
Cdd:COG0405   446 PRWHHQGLPDTLELePRFPPAVIAALRARGHKVEVVPDWSGgAQAILRDPDGvLEGAADPRR 507
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
1-533 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 627.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWD--GSKVAAVDGRETAPAAATDQLFMK 78
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDakDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  79 DGKPMAfydgVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKD-PYLAKDPDARAYF 157
Cdd:COG0405    81 AGDEIP----VRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAaERLARDPGAAAIF 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 yLPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQHptnPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:COG0405   157 -LPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAA---GGLLTLEDLAAYRAEWREPLSGTYRGY 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGtIALGQIFGMLESRDMAALKPvttpegqlaASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLD 317
Cdd:COG0405   233 TVYSMPPPSQG-IALLQILNILEGFDLAALGP---------DSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLS 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 318 KGYLAERSKLVG-ERSMGIAQPGMPPlalargkdaTPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMV--NGYLLNN 394
Cdd:COG0405   303 PAYAAERAALIDpDRATPSPRPGDPT---------GPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNN 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 395 QLTDFSFTSVDaaglpvANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAINL 474
Cdd:COG0405   374 RGDDFSLDPGH------PNALAPGKRPRSTMSPTIVLKD--GKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDA 445
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2273758829 475 PNFGSRNGPTELEL-GRTPESVVEGLKARGHEVVLSEQTSG-LQGVERNAGG-WFGAADPRR 533
Cdd:COG0405   446 PRWHHQGLPDTLELePRFPPAVIAALRARGHKVEVVPDWSGgAQAILRDPDGvLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
16-535 0e+00

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 518.69  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  16 IIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS--KVAAVDGRETAPAAATDQLFMKDGKPMAFydgVVGGR 93
Cdd:pfam01019   3 ILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKtgKVLVIDARETAPAAATKDMFDGKGDSKLS---LTGGL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  94 SVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKD-PYLAKDPDARAYFyLPDGTPRPAGSTLT 172
Cdd:pfam01019  80 AVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAeERLRADPGLRKIF-LPTGRVLKAGELLK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 173 NPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYRQSQICGfPTPSSGTIAL 252
Cdd:pfam01019 159 QPALAKTLELIAEEGPDAFYRGELAQQLVADLQA---NGGIITAEDLANYRVKIREPLSADYGGYTVYS-PPPSSGGIAL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 253 GQIFGMLESRDMaalkpvttpeGQLAASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLDKGYLAERSKLVGERS 332
Cdd:pfam01019 235 LQILNILEGFDL----------SSLLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLINPNA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 333 mgiaqpgmpplalARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMVNGY--LLNNQLTDFSFTSVDAAGLP 410
Cdd:pfam01019 305 -------------AFPSSYAPEDGGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTgiLLNNEMDDFSTPPGNAFGLD 371
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 411 V--ANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAINLPNFGSRNgPTELEL 488
Cdd:pfam01019 372 PspANAIAPGKRPLSSMAPTIVLDD--GKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQL-PDVLEV 448
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2273758829 489 GRT-PESVVEGLKARGHEVVLSEQTSGL---QGVERNAGGWFGAADPRREG 535
Cdd:pfam01019 449 EPGfPEEVLAELEARGHKVKVVEDSSSVgaiQIVRRTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
1-532 2.55e-122

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 369.10  E-value: 2.55e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS--KVAAVDGRETAPAAATDQLFM- 77
Cdd:TIGR00066   2 MVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKtkDTTAIDFRERAPAKATRDMFLd 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  78 KDGKPMAFyDGVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLA--TLLAKDPYLAKDPDARA 155
Cdd:TIGR00066  82 KSGNPLPG-KSLTGGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALAdtLELYEEVLLTTKEDSKD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 156 YFyLPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYR 235
Cdd:TIGR00066 161 IF-NPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQK---NGGIMTKKDLAAYDVEIRKPLSGDYR 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 236 QSQICGFPTPSSGTIALGQIFGMLESRDMAALkpvttPEGqlaaSSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGL 315
Cdd:TIGR00066 237 GYQVYTTPPPSSGGIHLLQALNILENFDLSQY-----GDG----SAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEEL 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 316 LDKGYLAERSKLVGERSMGiaqpgmPPLALARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMVNGY--LLN 393
Cdd:TIGR00066 308 LDKRYAKELAQSIKINKVD------PKSTIYPGAYQPNEGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTgiLLN 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 394 NQLTDFSFTSVDaaglpvANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAIN 473
Cdd:TIGR00066 382 NEMDDFSLKPGG------ANAVEPNKRPLSSMAPTIVLKD--GKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVS 453
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2273758829 474 LPNFGSRNGPTELEL-GRTPESVVEGLKARGHEVVLSEQT--SGLQGVERNAGGW-FGAADPR 532
Cdd:TIGR00066 454 EPRIHHQWLPDELRLeKGFPDDVLQLLKDMGHKVTLKEVFpmGVVQAIRVDPEGWlYGVSDPR 516
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
1-532 6.83e-98

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 308.37  E-value: 6.83e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS-KVAAVDGRETAPAAATDQLFMKD 79
Cdd:PRK09615   51 MVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLRTKNgNTTAIDFREMAPAKATRDMFLDD 130
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  80 GKPMAFYDGVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAK--DPYLAKDPDARAYF 157
Cdd:PRK09615  131 QGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTygSEVLPNHENSKAIF 210
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 YlPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQHptnPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:PRK09615  211 W-KEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKN---GGLITKEDLAAYKAVERTPISGDYRGY 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGTIALGQIFGMLESRDMAALKpvttpegqlAASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLD 317
Cdd:PRK09615  287 QVYSMPPPSSGGIHIVQILNILENFDMKKYG---------FGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTN 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 318 KGY---LAERSKLVGERsmgiaqpgmPPLALARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMV--NGYLL 392
Cdd:PRK09615  358 KAYaksIADQIDINKAK---------PSSEIRPGKLAPYESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVAgnSGILL 428
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 393 NNQLTDFSftsvDAAGLP--------VANRVEPGKRPRSSMSPLLVFDkpSGELTITLGSPGGSAIINYVGKTLLGTQDW 464
Cdd:PRK09615  429 NNQMDDFS----AKPGVPnvyglvggDANAVGPNKRPLSSMSPTIVVK--DGKTWLVTGSPGGSRIITTVLQMVVNSIDY 502
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2273758829 465 GLNLQQAINLPNFGSRNGPTEL--ELGRTPESvVEGLKARGHEVVLSEQTSGLQGVERNAGG-WFGAADPR 532
Cdd:PRK09615  503 GMNVAEATNAPRFHHQWLPDELrvEKGFSPDT-LKLLEAKGQKVALKEAMGSTQSIMVGPDGeLYGASDPR 572
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
1-533 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 627.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWD--GSKVAAVDGRETAPAAATDQLFMK 78
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDakDGKVTALDGRGTAPAAATPDMYLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  79 DGKPMAfydgVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKD-PYLAKDPDARAYF 157
Cdd:COG0405    81 AGDEIP----VRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAaERLARDPGAAAIF 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 yLPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQHptnPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:COG0405   157 -LPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAA---GGLLTLEDLAAYRAEWREPLSGTYRGY 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGtIALGQIFGMLESRDMAALKPvttpegqlaASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLD 317
Cdd:COG0405   233 TVYSMPPPSQG-IALLQILNILEGFDLAALGP---------DSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLS 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 318 KGYLAERSKLVG-ERSMGIAQPGMPPlalargkdaTPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMV--NGYLLNN 394
Cdd:COG0405   303 PAYAAERAALIDpDRATPSPRPGDPT---------GPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVpgTGFLLNN 373
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 395 QLTDFSFTSVDaaglpvANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAINL 474
Cdd:COG0405   374 RGDDFSLDPGH------PNALAPGKRPRSTMSPTIVLKD--GKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDA 445
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2273758829 475 PNFGSRNGPTELEL-GRTPESVVEGLKARGHEVVLSEQTSG-LQGVERNAGG-WFGAADPRR 533
Cdd:COG0405   446 PRWHHQGLPDTLELePRFPPAVIAALRARGHKVEVVPDWSGgAQAILRDPDGvLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
16-535 0e+00

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 518.69  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  16 IIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS--KVAAVDGRETAPAAATDQLFMKDGKPMAFydgVVGGR 93
Cdd:pfam01019   3 ILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKtgKVLVIDARETAPAAATKDMFDGKGDSKLS---LTGGL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  94 SVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKD-PYLAKDPDARAYFyLPDGTPRPAGSTLT 172
Cdd:pfam01019  80 AVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAeERLRADPGLRKIF-LPTGRVLKAGELLK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 173 NPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYRQSQICGfPTPSSGTIAL 252
Cdd:pfam01019 159 QPALAKTLELIAEEGPDAFYRGELAQQLVADLQA---NGGIITAEDLANYRVKIREPLSADYGGYTVYS-PPPSSGGIAL 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 253 GQIFGMLESRDMaalkpvttpeGQLAASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLDKGYLAERSKLVGERS 332
Cdd:pfam01019 235 LQILNILEGFDL----------SSLLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLINPNA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 333 mgiaqpgmpplalARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMVNGY--LLNNQLTDFSFTSVDAAGLP 410
Cdd:pfam01019 305 -------------AFPSSYAPEDGGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTgiLLNNEMDDFSTPPGNAFGLD 371
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 411 V--ANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAINLPNFGSRNgPTELEL 488
Cdd:pfam01019 372 PspANAIAPGKRPLSSMAPTIVLDD--GKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHHQL-PDVLEV 448
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2273758829 489 GRT-PESVVEGLKARGHEVVLSEQTSGL---QGVERNAGGWFGAADPRREG 535
Cdd:pfam01019 449 EPGfPEEVLAELEARGHKVKVVEDSSSVgaiQIVRRTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
1-532 2.55e-122

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 369.10  E-value: 2.55e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS--KVAAVDGRETAPAAATDQLFM- 77
Cdd:TIGR00066   2 MVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKtkDTTAIDFRERAPAKATRDMFLd 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  78 KDGKPMAFyDGVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLA--TLLAKDPYLAKDPDARA 155
Cdd:TIGR00066  82 KSGNPLPG-KSLTGGLAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALAdtLELYEEVLLTTKEDSKD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 156 YFyLPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYR 235
Cdd:TIGR00066 161 IF-NPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQK---NGGIMTKKDLAAYDVEIRKPLSGDYR 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 236 QSQICGFPTPSSGTIALGQIFGMLESRDMAALkpvttPEGqlaaSSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGL 315
Cdd:TIGR00066 237 GYQVYTTPPPSSGGIHLLQALNILENFDLSQY-----GDG----SAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEEL 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 316 LDKGYLAERSKLVGERSMGiaqpgmPPLALARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMVNGY--LLN 393
Cdd:TIGR00066 308 LDKRYAKELAQSIKINKVD------PKSTIYPGAYQPNEGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTgiLLN 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 394 NQLTDFSFTSVDaaglpvANRVEPGKRPRSSMSPLLVFDKpsGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAIN 473
Cdd:TIGR00066 382 NEMDDFSLKPGG------ANAVEPNKRPLSSMAPTIVLKD--GKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVS 453
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2273758829 474 LPNFGSRNGPTELEL-GRTPESVVEGLKARGHEVVLSEQT--SGLQGVERNAGGW-FGAADPR 532
Cdd:TIGR00066 454 EPRIHHQWLPDELRLeKGFPDDVLQLLKDMGHKVTLKEVFpmGVVQAIRVDPEGWlYGVSDPR 516
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
1-532 6.83e-98

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 308.37  E-value: 6.83e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLVWDGS-KVAAVDGRETAPAAATDQLFMKD 79
Cdd:PRK09615   51 MVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLRTKNgNTTAIDFREMAPAKATRDMFLDD 130
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  80 GKPMAFYDGVVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAK--DPYLAKDPDARAYF 157
Cdd:PRK09615  131 QGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTygSEVLPNHENSKAIF 210
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 YlPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQHptnPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:PRK09615  211 W-KEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKN---GGLITKEDLAAYKAVERTPISGDYRGY 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGTIALGQIFGMLESRDMAALKpvttpegqlAASSDAIHLYSEAARLAFADRNQYVADSDFVSVPVKGLLD 317
Cdd:PRK09615  287 QVYSMPPPSSGGIHIVQILNILENFDMKKYG---------FGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTN 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 318 KGY---LAERSKLVGERsmgiaqpgmPPLALARGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLMV--NGYLL 392
Cdd:PRK09615  358 KAYaksIADQIDINKAK---------PSSEIRPGKLAPYESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVAgnSGILL 428
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 393 NNQLTDFSftsvDAAGLP--------VANRVEPGKRPRSSMSPLLVFDkpSGELTITLGSPGGSAIINYVGKTLLGTQDW 464
Cdd:PRK09615  429 NNQMDDFS----AKPGVPnvyglvggDANAVGPNKRPLSSMSPTIVVK--DGKTWLVTGSPGGSRIITTVLQMVVNSIDY 502
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2273758829 465 GLNLQQAINLPNFGSRNGPTEL--ELGRTPESvVEGLKARGHEVVLSEQTSGLQGVERNAGG-WFGAADPR 532
Cdd:PRK09615  503 GMNVAEATNAPRFHHQWLPDELrvEKGFSPDT-LKLLEAKGQKVALKEAMGSTQSIMVGPDGeLYGASDPR 572
PLN02180 PLN02180
gamma-glutamyl transpeptidase 4
1-472 1.71e-62

gamma-glutamyl transpeptidase 4


Pssm-ID: 177836  Cd Length: 639  Bit Score: 216.47  E-value: 1.71e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829   1 MVAAANPLAVDAGYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLV--WDGSKVAAVDGRETAPAAATDQLFMK 78
Cdd:PLN02180   84 VVAADDARCSEIGASVLRRGGHAVDAAVAITLCIGVVNPMSSGIGGGSFLIVssQKDSKAEAFDMRETAPLAASKDMYKN 163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  79 DGKPMAfydgvVGGRSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLA-KDPYLAKDPDARAYF 157
Cdd:PLN02180  164 DASAKS-----LGALSMGVPGEIAGLYEAWKRYGRLPWKPLFEPAIELARDGFVVHPYLGKAISsHAAMILKDPGLRSVF 238
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 158 YlPDGTPRPAGSTLTNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYRQS 237
Cdd:PLN02180  239 S-RNGQVLKPGETCYNPELAQSLETISEQGPGAFYNGTIGEKLVKDVKK---AGGIITMDDLRSYEVLVTDAMSVDVMGY 314
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 238 QICGFPTPSSGTIALGQIFGMLESrdmaaLKPVTTPEGqlaaSSDAIHLYSEAARLAFADRNQyVADSDFVSV--PVKGL 315
Cdd:PLN02180  315 TIHGMPPPSGGTLGFSMVIDILDS-----YSNLYTASG----RELGLHRLIEAMKHMFAARMD-LGDPEFVNItnAMNQM 384
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 316 LDKGYLAERSKLVGERSMGIAQPGMPPLALARGKdatpelpSTSHVSIVDKAGMAVSMTSSIEDGFGSRLM--VNGYLLN 393
Cdd:PLN02180  385 LSKAHAEEIQKRIFDNTTFPPEYYLNRWSQLRDQ-------GTSHFCIVDADRNSVSMTSTVNYGFGAGVLspSTGIVLN 457
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 394 NQLTDFSF-TSVDAAGLPVA--NRVEPGKRPRSSMSPLLVfdKPSGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQ 470
Cdd:PLN02180  458 NEMDDFSTpAEITPDMLPPAptNFIEPNKRPLSSMTPLVI--TKDGEFVAALGGAGGMHIIPAVLQVFLNCFVLNMKPKE 535

                  ..
gi 2273758829 471 AI 472
Cdd:PLN02180  536 AV 537
PLN02198 PLN02198
glutathione gamma-glutamylcysteinyltransferase
13-539 2.24e-56

glutathione gamma-glutamylcysteinyltransferase


Pssm-ID: 177849  Cd Length: 573  Bit Score: 198.38  E-value: 2.24e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  13 GYQIIRAGGSAVDAAIAVQLVLTLVEPQSSGIGGGSLLLV-WDGSKVAAVDGRETAPAAATDQlfMKDGKPMAFYDGVVg 91
Cdd:PLN02198   47 GMNVLREGGNAIDASVAAALCLGVVSPASSGIGGGAFTLIkLANGEEIAYDSRETAPLSATEN--MYGGNVELKKKGAL- 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829  92 grSVGAPGTVRALALAHQRYGKLPWAALFEPAITLAEQGFVISPRLATLLAKDPYLAKDPDARAYFYLPDGTPRPAGSTL 171
Cdd:PLN02198  124 --SVGVPGEVAGLFTAWKQHGKLPWKRLVRPAEKLAAEGFKISKYLYMQMNATRSDILADKGLSDLFVSNGELKKPGTIC 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 172 TNPALAKVLRTLATQGADAFYQGPLAQAMVAKVRQhptNPGVLAAADLASYRAKLRDGLCFDYRQSQICGFPTPSSGTIA 251
Cdd:PLN02198  202 HNPKLALTLRLIGEYGPKAFYNGTVGVNLVRDIQK---SGGIITLKDLQSYRVKVKEPLSADILGYRVLGMPPPSSGGAA 278
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 252 LGQIFGMLESRDMaalkpvttPEGqlAASSDAIHLYSEAARLAFADRNQyVADSDFVSVP--VKGLLDKGYLAE-RSKLV 328
Cdd:PLN02198  279 MMLILNILAQYGI--------PSG--VSGPLGVHRLIEALKHAFAVRMN-LGDPDFVDVTkvVSDMLSPKFAQDlKSKIN 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 329 GERSMGIAQPGmpplalarGKDATPELPSTSHVSIVDKAGMAVSMTSSIEDGFGSRLM--VNGYLLNNQLTDFSFTSVDA 406
Cdd:PLN02198  348 DNKTFDPKHYG--------GRWNQIDDHGTSHLSIIDSERNAVSMTSTINGYFGALMLspSTGIVLNNEMDDFSIPMKSG 419
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2273758829 407 AGLPV-----ANRVEPGKRPRSSMSPLLVFDkpSGELTITLGSPGGSAIINYVGKTLLGTQDWGLNLQQAIN-------- 473
Cdd:PLN02198  420 GNLDVpppapANFIRPGKRPLSSMTPTIVLK--DGKVKAAVGASGGANIIAGTTEVYLNHFFLKMDPLSSVLapriyhql 497
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2273758829 474 LPNFGSRNGPTEL--ELGRTPESVVEGLKARGHevVLSEQTSG------LQGVERNAGG---WFGAADPRREGIAKG 539
Cdd:PLN02198  498 IPNRASYENWTTVynDHFEIPKATRVVLEKKGH--VLSPIAGGtiaqfiVQESGENSGGrseLVAVSDPRKGGFPSG 572
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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