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Conserved domains on  [gi|2321081033|ref|WP_263957255|]
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FAD-dependent oxidoreductase [Pseudomonas aeruginosa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Phn_aa_oxid super family cl26295
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


The actual alignment was detected with superfamily member TIGR03329:

Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 823.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033   5 PFWLDQALRSEHAAPCPPLAGDTRADVCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  85 TLERLFGLTEAIRLVRASEDSIRAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGINSFAKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 245 FPQFERSVAIVSSDMLITELRPDLLHEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 325 RQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 2321081033 405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKERAEDAGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
 
Name Accession Description Interval E-value
Phn_aa_oxid TIGR03329
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 823.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033   5 PFWLDQALRSEHAAPCPPLAGDTRADVCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  85 TLERLFGLTEAIRLVRASEDSIRAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGINSFAKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 245 FPQFERSVAIVSSDMLITELRPDLLHEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 325 RQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 2321081033 405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKERAEDAGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-407 1.25e-74

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 238.65  E-value: 1.25e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  27 TRADVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGGCalswsakfftLERLFGLTEAIRLVRASEDSI 106
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARR--GLDVTVLERGRPGSGASGRNAGQ----------LRPGLAALADRALVRLAREAL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 107 RAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGINSfakRPL--ADVQRLA---GSRRHLEGWFSPAA 181
Cdd:COG0665    69 DLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPV---ELLdaAELREREpglGSPDYAGGLYDPDD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 182 ATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVLALNAWMARAFPQFERSVAI--VSS 257
Cdd:COG0665   146 GHVDPAKLVRALARAARAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLrpVRG 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 258 DMLITELRPDLLHEIGLTsgvsvlDSRifvHYYHNTPDGRLMLGkggntfayGGRMLPVFDRPSP--YLRQLRGSLREFF 335
Cdd:COG0665   226 YVLVTEPLPDLPLRPVLD------DTG---VYLRPTADGRLLVG--------GTAEPAGFDRAPTpeRLEALLRRLRRLF 288

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2321081033 336 PEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTRSPL 407
Cdd:COG0665   289 PALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPF 360
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-394 3.11e-52

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 179.52  E-value: 3.11e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEAD-LCGAGASGRNGGCALSWsakfftlerlFGLTEAIRLVRASEDSIRA 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARR--GLSVTLLERGdDPGSGASGRNAGLIHPG----------LRYLEPSELARLALEALDL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 109 IGAFCQRYGVEADYRLDGTLYTATSPAQvGSTDSVIAALERHGINSFAKRPLADVQRLAGSRRHLEGWFSPAAATVQPGK 188
Cdd:pfam01266  69 WEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRGGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 189 LVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRvvADRVVLALNAWMAR-AFPQFERSVAIVSSDMLITELRPD 267
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGE--ADAVVNAAGAWADLlALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 268 LLheigLTSGVSVLDSRIFVHYYHNTPDGRLMLGKggnTFAYGGRMLPVFDRPSpyLRQLRGSLREFFPEFAEvaIEASW 347
Cdd:pfam01266 226 AL----LILPVPITVDPGRGVYLRPRADGRLLLGG---TDEEDGFDDPTPDPEE--IEELLEAARRLFPALAD--IERAW 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 2321081033 348 NGPSDrSVTGLPFFGRLDGRdNVFYGFGYSGSGVGPCHMGGQILSSL 394
Cdd:pfam01266 295 AGLRP-LPDGLPIIGRPGSP-GLYLATGHGGHGLTLAPGIGKLLAEL 339
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
30-234 1.36e-07

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 53.29  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHDPGLDVVLV--EADLcGAGASGRNGGCALSwsakfftlerlfGL-----TEAIRLVRAS 102
Cdd:PRK11728    4 DFVIIGGGIVGLSTAMQLQERYPGARIAVLekESGP-ARHQTGHNSGVIHA------------GVyytpgSLKARFCRRG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 103 EDSIRaigAFCQRYGVeaDYRLDGTLYTATSPAQVGSTDSVIAALERHGInsfakrplaDVQRLAGSR--------RHLE 174
Cdd:PRK11728   71 NEATK---AFCDQHGI--PYEECGKLLVATSELELERMEALYERARANGI---------EVERLDAEElrerepniRGLG 136

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2321081033 175 GWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGL-EHGRPAEVVTPHGRVVADRVV 234
Cdd:PRK11728  137 AIFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALdEHANGVVVRTTQGEYEARTLI 197
 
Name Accession Description Interval E-value
Phn_aa_oxid TIGR03329
putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 ...
 5-452 0e+00

putative aminophosphonate oxidoreductase; This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.


Pssm-ID: 274522 [Multi-domain]  Cd Length: 460  Bit Score: 823.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033   5 PFWLDQALRSEHAAPCPPLAGDTRADVCIVGGGYTGLWTAIMLKEHDPGLDVVLVEADLCGAGASGRNGGCALSWSAKFF 84
Cdd:TIGR03329   1 PFWLEQALALEQPDPAPPLVGDTQADVCIVGGGFTGLWTAIMIKQQRPALDVLVLEADLCGAGASGRNGGCMLTWSTKFF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  85 TLERLFGLTEAIRLVRASEDSIRAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGINSFAKRPLADVQ 164
Cdd:TIGR03329  81 TLKRLFGEAEAARLVKASEQAVLEIAAFCEQHNIDAQLRLDGTLYTATNPAQVGSMDPVVDALERRGINSWQRLSEGELA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 165 RLAGSRRHLEGWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADRVVLALNAWMARA 244
Cdd:TIGR03329 161 RRTGSARHLEGFYSPVAASVQPGLLVRGLRRVALELGVEIHENTPMTGLEEGQPAVVRTPDGQVTADKVVLALNAWMASH 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 245 FPQFERSVAIVSSDMLITELRPDLLHEIGLTSGVSVLDSRIFVHYYHNTPDGRLMLGKGGNTFAYGGRMLPVFDRPSPYL 324
Cdd:TIGR03329 241 FPQFERSIAIVSSDMVITEPAPDLLAATGLDHGTSVLDSRIFVHYYRSTPDGRLMLGKGGNTFAYGGRMLPVFNQPSPYE 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 325 RQLRGSLREFFPEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTR 404
Cdd:TIGR03329 321 ALLTRSLRKFFPALAEVPIAASWNGPSDRSVTGLPFFGRLNGQPNVFYGFGYSGNGVAPSRMGGQILSSLVLGLDNPWTR 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 2321081033 405 SPLTQGPLGRFPPEPIRYVGSLMVRNAIRRKERAEDAGRRPRHLDVRL 452
Cdd:TIGR03329 401 SPLVKGPLGYFPPEPIRYLGALVVRNAIRRKERAEDEGRRPFLLDKWL 448
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
27-407 1.25e-74

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 238.65  E-value: 1.25e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  27 TRADVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGGCalswsakfftLERLFGLTEAIRLVRASEDSI 106
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARR--GLDVTVLERGRPGSGASGRNAGQ----------LRPGLAALADRALVRLAREAL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 107 RAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGINSfakRPL--ADVQRLA---GSRRHLEGWFSPAA 181
Cdd:COG0665    69 DLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALGLPV---ELLdaAELREREpglGSPDYAGGLYDPDD 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 182 ATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVLALNAWMARAFPQFERSVAI--VSS 257
Cdd:COG0665   146 GHVDPAKLVRALARAARAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLrpVRG 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 258 DMLITELRPDLLHEIGLTsgvsvlDSRifvHYYHNTPDGRLMLGkggntfayGGRMLPVFDRPSP--YLRQLRGSLREFF 335
Cdd:COG0665   226 YVLVTEPLPDLPLRPVLD------DTG---VYLRPTADGRLLVG--------GTAEPAGFDRAPTpeRLEALLRRLRRLF 288

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2321081033 336 PEFAEVAIEASWNGPSDRSVTGLPFFGRLDGRDNVFYGFGYSGSGVGPCHMGGQILSSLALGLDNPWTRSPL 407
Cdd:COG0665   289 PALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPF 360
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 30-394 3.11e-52

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 179.52  E-value: 3.11e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEAD-LCGAGASGRNGGCALSWsakfftlerlFGLTEAIRLVRASEDSIRA 108
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARR--GLSVTLLERGdDPGSGASGRNAGLIHPG----------LRYLEPSELARLALEALDL 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 109 IGAFCQRYGVEADYRLDGTLYTATSPAQvGSTDSVIAALERHGINSFAKRPLADVQRLAGSRRHLEGWFSPAAATVQPGK 188
Cdd:pfam01266  69 WEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRGGLFYPDGGHVDPAR 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 189 LVRGLRRVALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRvvADRVVLALNAWMAR-AFPQFERSVAIVSSDMLITELRPD 267
Cdd:pfam01266 148 LLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGE--ADAVVNAAGAWADLlALPGLRLPVRPVRGQVLVLEPLPE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 268 LLheigLTSGVSVLDSRIFVHYYHNTPDGRLMLGKggnTFAYGGRMLPVFDRPSpyLRQLRGSLREFFPEFAEvaIEASW 347
Cdd:pfam01266 226 AL----LILPVPITVDPGRGVYLRPRADGRLLLGG---TDEEDGFDDPTPDPEE--IEELLEAARRLFPALAD--IERAW 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 2321081033 348 NGPSDrSVTGLPFFGRLDGRdNVFYGFGYSGSGVGPCHMGGQILSSL 394
Cdd:pfam01266 295 AGLRP-LPDGLPIIGRPGSP-GLYLATGHGGHGLTLAPGIGKLLAEL 339
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 26-236 1.00e-09

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 60.23  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  26 DTRADVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGAGASGRNGG---CALSWSAKfftlerlfglteairlvRAS 102
Cdd:COG1053     1 DHEYDVVVVGSGGAGLRAALEAAEA--GLKVLVLEKVPPRGGHTAAAQGginAAGTNVQK-----------------AAG 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 103 EDSIRAIGAFCQRYGveaDYRLDGTL---YTATSPAqvgstdsVIAALERHGINsFAKRPLADVQRLAG---SRRHlegw 176
Cdd:COG1053    62 EDSPEEHFYDTVKGG---DGLADQDLveaLAEEAPE-------AIDWLEAQGVP-FSRTPDGRLPQFGGhsvGRTC---- 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2321081033 177 fspaAATVQPGK-LVRGLRRVALQLGVRLYEGTPMRGL--EHGRP--AEVVTPHGRVV---ADRVVLA 236
Cdd:COG1053   127 ----YAGDGTGHaLLATLYQAALRLGVEIFTETEVLDLivDDGRVvgVVARDRTGEIVrirAKAVVLA 190
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
30-234 1.36e-07

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 53.29  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHDPGLDVVLV--EADLcGAGASGRNGGCALSwsakfftlerlfGL-----TEAIRLVRAS 102
Cdd:PRK11728    4 DFVIIGGGIVGLSTAMQLQERYPGARIAVLekESGP-ARHQTGHNSGVIHA------------GVyytpgSLKARFCRRG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 103 EDSIRaigAFCQRYGVeaDYRLDGTLYTATSPAQVGSTDSVIAALERHGInsfakrplaDVQRLAGSR--------RHLE 174
Cdd:PRK11728   71 NEATK---AFCDQHGI--PYEECGKLLVATSELELERMEALYERARANGI---------EVERLDAEElrerepniRGLG 136

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2321081033 175 GWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGL-EHGRPAEVVTPHGRVVADRVV 234
Cdd:PRK11728  137 AIFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALdEHANGVVVRTTQGEYEARTLI 197
PRK00711 PRK00711
D-amino acid dehydrogenase;
97-240 3.57e-07

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 52.11  E-value: 3.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  97 RLVRASEDSIRAIGAFCQRYGVEADYRLDGTLYTATSPAQVGSTDSVIAALERHGInsfakrP--LADVQRLAGsrrhle 174
Cdd:PRK00711  107 RMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEAGV------PyeLLDRDELAA------ 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 175 gwFSPAAATVQpGKLVRGLR-----------------RVALQLGVRLYEGTPMRGLEH--GRPAEVVTPHGRVVADRVVL 235
Cdd:PRK00711  175 --VEPALAGVR-HKLVGGLRlpndetgdcqlftqrlaAMAEQLGVKFRFNTPVDGLLVegGRITGVQTGGGVITADAYVV 251


                  ....*
gi 2321081033 236 ALNAW 240
Cdd:PRK00711  252 ALGSY 256
solA PRK11259
N-methyl-L-tryptophan oxidase;
175-255 3.14e-06

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 49.06  E-value: 3.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 175 GWFSPAAATVQPGKLVRGLRRVALQLGVRLYEGTPMRGLEHGRPA-EVVTPHGRVVADRVVLALNAWMARAFPQFERSVA 253
Cdd:PRK11259  137 ALFEPDGGFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGvTVTTADGTYEAKKLVVSAGAWVKDLLPPLELPLT 216


                  ..
gi 2321081033 254 IV 255
Cdd:PRK11259  217 PV 218
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 30-249 4.42e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 42.91  E-value: 4.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEADLCGA-GASG-RNGgcALS--WSAKFFTLERLF--GLTEAIRLVRASE 103
Cdd:PRK01747  262 DAAIIGGGIAGAALALALARR--GWQVTLYEADEAPAqGASGnRQG--ALYplLSKDDNALSRFFraAFLFARRFYDALP 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 104 dsiraigafcqRYGVEADYRLDGTLYTATSPAqvgSTDSVIAALERHGINSFAkRPL--ADVQRLAGSRRHLEGWFSPAA 181
Cdd:PRK01747  338 -----------AAGVAFDHDWCGVLQLAWDEK---SAEKIAKMLALGLPAELA-RALdaEEAEELAGLPVPCGGIFYPQG 402

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2321081033 182 ATVQPGKLVRGLRRvALQLGVRLYEGTPMRGLEHGRPAEVVTPHGRVVADR--VVLAlNAWMARAFPQFE 249
Cdd:PRK01747  403 GWLCPAELCRALLA-LAGQQLTIHFGHEVARLEREDDGWQLDFAGGTLASApvVVLA-NGHDAARFAQTA 470
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
30-74 1.13e-03

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 41.54  E-value: 1.13e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2321081033  30 DVCIVGGGYTGlwTAIMLKEHDPGLDVVLVEADLCGAGASGRNGG 74
Cdd:PRK11101    8 DVIIIGGGATG--AGIARDCALRGLRCILVERHDIATGATGRNHG 50
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
28-61 3.75e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 39.58  E-value: 3.75e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2321081033  28 RADVCIVGGGYTGLWTAIMLKEHDPGLDVVLVEA 61
Cdd:PRK07333    1 QCDVVIAGGGYVGLALAVALKQAAPHLPVTVVDA 34
PRK06854 PRK06854
adenylyl-sulfate reductase subunit alpha;
30-72 5.29e-03

adenylyl-sulfate reductase subunit alpha;


Pssm-ID: 235879 [Multi-domain]  Cd Length: 608  Bit Score: 39.14  E-value: 5.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHDPGLDVVLVE---ADLCGAGASGRN 72
Cdd:PRK06854   13 DILIIGGGMAGCGAAFEAKEWAPDLKVLIVEkanIKRSGAVAQGLS 58
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 27-62 6.10e-03

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 38.77  E-value: 6.10e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2321081033  27 TRADVCIVGGGYTGLWTAIMLKEHdpGLDVVLVEAD 62
Cdd:COG0654     2 MRTDVLIVGGGPAGLALALALARA--GIRVTVVERA 35
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
33-84 8.67e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 34.81  E-value: 8.67e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2321081033  33 IVGGGYTGLWTAIMLKEHdpGLDVVLVEA--DLCGAGASGRNGGCALSWSAKFF 84
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKR--GFRVLVLEKrdRLGGNAYSYRVPGYVFDYGAHIF 52
PRK08275 PRK08275
putative oxidoreductase; Provisional
 30-60 9.54e-03

putative oxidoreductase; Provisional


Pssm-ID: 181346 [Multi-domain]  Cd Length: 554  Bit Score: 38.49  E-value: 9.54e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2321081033  30 DVCIVGGGYTGLWTAIMLKEHDPGLDVVLVE 60
Cdd:PRK08275   11 DILVIGGGTAGPMAAIKAKERNPALRVLLLE 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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