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Conserved domains on  [gi|2404076212|ref|WP_268257664|]
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6-phosphogluconolactonase [Streptomyces fumanus]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 10796786)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 10-252 3.80e-88

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


:

Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 261.15  E-value: 3.80e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  10 VHRDKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALAsspaRDAIDWGRLDLWWGDERFLPEGDPDRNV 89
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALA----AQPLDWSRIHLFLGDERYVPLDHADSNT 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  90 TQAREALLDAVPLDPERVHAMPASDgpygSDVDAAAEAYAQELARAAGPEShaaVPSFDVLLLGVGPDTHVASLFPELPA 169
Cdd:TIGR01198  77 GLAREALLDRVAIPASNIHPMPTEL----SDIEEAAELYEQELAAAFQPIV---FPVFDLLLLGMGPDGHTASLFPHTPA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 170 VRETERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALS-GAGEIQAPAAGAVGRARTLWLLDSAA 248
Cdd:TIGR01198 150 LQETERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAvEAEPYPLPAAGVLHSGKTLWLLDYAA 229


                  ....
gi 2404076212 249 ASQL 252
Cdd:TIGR01198 230 ARKL 233
 
Name Accession Description Interval E-value
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 10-252 3.80e-88

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 261.15  E-value: 3.80e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  10 VHRDKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALAsspaRDAIDWGRLDLWWGDERFLPEGDPDRNV 89
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALA----AQPLDWSRIHLFLGDERYVPLDHADSNT 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  90 TQAREALLDAVPLDPERVHAMPASDgpygSDVDAAAEAYAQELARAAGPEShaaVPSFDVLLLGVGPDTHVASLFPELPA 169
Cdd:TIGR01198  77 GLAREALLDRVAIPASNIHPMPTEL----SDIEEAAELYEQELAAAFQPIV---FPVFDLLLLGMGPDGHTASLFPHTPA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 170 VRETERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALS-GAGEIQAPAAGAVGRARTLWLLDSAA 248
Cdd:TIGR01198 150 LQETERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAvEAEPYPLPAAGVLHSGKTLWLLDYAA 229


                  ....
gi 2404076212 249 ASQL 252
Cdd:TIGR01198 230 ARKL 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 5-253 4.00e-83

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 248.92  E-value: 4.00e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212   5 TPQLVVHRDKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALASSPARDAIDWGRLDLWWGDERF-LPEG 83
Cdd:COG0363     1 KMRVIIFPDAEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEGGLDWSRVHVFNLDEYVgLPPD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  84 DPDRNVTQAREALLDAVPLDPERVHAMPASDGpygsDVDAAAEAYAQELARAagpeshaavPSFDVLLLGVGPDTHVASL 163
Cdd:COG0363    81 HPQSNRRFMREALLDHVDIPPENIHIPDGEAE----DPEAAAARYEALIAEA---------GGIDLQLLGIGEDGHIAFN 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 164 FPELPAVRETERTVVGVH-----------GSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAA 232
Cdd:COG0363   148 FPGSPFLSETDRVVTLDEstrqanarffgSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPAS 227

                         250       260
                  ....*....|....*....|.
gi 2404076212 233 GAVGRARTLWLLDSAAASQLP 253
Cdd:COG0363   228 ILQGHPNVTWFLDEAAASLLT 248
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
13-242 3.94e-82

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 245.61  E-value: 3.94e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  13 DKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALASSPARdaIDWGRLDLWWGDERFLPEGDPDRNVTQA 92
Cdd:pfam01182   2 DAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPAR--LDWSRVHVFWGDERCVPPDDPDSNYGMA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  93 REALLDAVPLDPERVHAMPASdgpyGSDVDAAAEAYAQELARAAGpesHAAVPSFDVLLLGVGPDTHVASLFPELPAVRE 172
Cdd:pfam01182  80 REALLSHVPIPASNVHPIPAS----AADPEEAAAAYEAELRELLP---DLELPVFDLVLLGMGPDGHTASLFPGSPALEE 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2404076212 173 TERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEiQAPAAGA-VGRARTLW 242
Cdd:pfam01182 153 TDRLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAALVrPGAGETVW 222
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 15-244 7.61e-78

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 234.76  E-value: 7.61e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  15 ELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALAsspARDAIDWGRLDLWWGDERFLPEGDPDRNVTQARE 94
Cdd:cd01400     1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLA---AAPALDWSKVHVFLGDERCVPPDDPDSNYRLARE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  95 ALLDAVPLDPERVHAMPASDGPygsdvDAAAEAYAQELARAAGPeshaaVPSFDVLLLGVGPDTHVASLFPELPA-VRET 173
Cdd:cd01400    78 ALLSHVAIPAANIHPIPTELGP-----EDAAAAYEKELRALFGG-----VPPFDLVLLGMGPDGHTASLFPGHPAlLEET 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2404076212 174 ERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAAGAVGRA-RTLWLL 244
Cdd:cd01400   148 DRLVVAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPgEVLWFL 219
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 36-255 8.50e-37

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 131.13  E-value: 8.50e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  36 RGHASVVLTGGrNGNGLLAALASSPARDAIDWGRLDLWWGDERFLPEGDPDRNVTQAREALLDAVPLDPERVHAMPASdg 115
Cdd:PLN02360   41 RGVFAIALSGG-SLISFMGKLCEAPYNKTVDWAKWYIFWADERVVAKNHADSNYKLAKDGLLSKVPVVPSHVYSINDT-- 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 116 pygSDVDAAAEAYA---QEL--ARAAGPESHAAVPSFDVLLLGVGPDTHVASLFPELPAVRETERTVVGVHGSPKPPPTR 190
Cdd:PLN02360  118 ---VTAEEAATDYEfaiRQLvkTRTIGVSDISDCPKFDLILLGMGSDGHVASLFPNHPALEEKDDWVTFITDSPKPPPER 194

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 191 VTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGE-IQAPA--AGAV--GRARTLWLLDSAAASQLPRS 255
Cdd:PLN02360  195 ITFTLPVINSASNVAVVATGESKANAVHLAIDDVTEgPDAPSlpARMVqpTKGKLVWFLDKPAASKLDGF 264
 
Name Accession Description Interval E-value
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 10-252 3.80e-88

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 261.15  E-value: 3.80e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  10 VHRDKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALAsspaRDAIDWGRLDLWWGDERFLPEGDPDRNV 89
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALA----AQPLDWSRIHLFLGDERYVPLDHADSNT 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  90 TQAREALLDAVPLDPERVHAMPASDgpygSDVDAAAEAYAQELARAAGPEShaaVPSFDVLLLGVGPDTHVASLFPELPA 169
Cdd:TIGR01198  77 GLAREALLDRVAIPASNIHPMPTEL----SDIEEAAELYEQELAAAFQPIV---FPVFDLLLLGMGPDGHTASLFPHTPA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 170 VRETERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALS-GAGEIQAPAAGAVGRARTLWLLDSAA 248
Cdd:TIGR01198 150 LQETERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAvEAEPYPLPAAGVLHSGKTLWLLDYAA 229


                  ....
gi 2404076212 249 ASQL 252
Cdd:TIGR01198 230 ARKL 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 5-253 4.00e-83

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 248.92  E-value: 4.00e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212   5 TPQLVVHRDKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALASSPARDAIDWGRLDLWWGDERF-LPEG 83
Cdd:COG0363     1 KMRVIIFPDAEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEGGLDWSRVHVFNLDEYVgLPPD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  84 DPDRNVTQAREALLDAVPLDPERVHAMPASDGpygsDVDAAAEAYAQELARAagpeshaavPSFDVLLLGVGPDTHVASL 163
Cdd:COG0363    81 HPQSNRRFMREALLDHVDIPPENIHIPDGEAE----DPEAAAARYEALIAEA---------GGIDLQLLGIGEDGHIAFN 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 164 FPELPAVRETERTVVGVH-----------GSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAA 232
Cdd:COG0363   148 FPGSPFLSETDRVVTLDEstrqanarffgSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPAS 227

                         250       260
                  ....*....|....*....|.
gi 2404076212 233 GAVGRARTLWLLDSAAASQLP 253
Cdd:COG0363   228 ILQGHPNVTWFLDEAAASLLT 248
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
13-242 3.94e-82

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 245.61  E-value: 3.94e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  13 DKELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALASSPARdaIDWGRLDLWWGDERFLPEGDPDRNVTQA 92
Cdd:pfam01182   2 DAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPAR--LDWSRVHVFWGDERCVPPDDPDSNYGMA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  93 REALLDAVPLDPERVHAMPASdgpyGSDVDAAAEAYAQELARAAGpesHAAVPSFDVLLLGVGPDTHVASLFPELPAVRE 172
Cdd:pfam01182  80 REALLSHVPIPASNVHPIPAS----AADPEEAAAAYEAELRELLP---DLELPVFDLVLLGMGPDGHTASLFPGSPALEE 152

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2404076212 173 TERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEiQAPAAGA-VGRARTLW 242
Cdd:pfam01182 153 TDRLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAALVrPGAGETVW 222
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 15-244 7.61e-78

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 234.76  E-value: 7.61e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  15 ELMAEAAAARLITKVVDAQTSRGHASVVLTGGRNGNGLLAALAsspARDAIDWGRLDLWWGDERFLPEGDPDRNVTQARE 94
Cdd:cd01400     1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLA---AAPALDWSKVHVFLGDERCVPPDDPDSNYRLARE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  95 ALLDAVPLDPERVHAMPASDGPygsdvDAAAEAYAQELARAAGPeshaaVPSFDVLLLGVGPDTHVASLFPELPA-VRET 173
Cdd:cd01400    78 ALLSHVAIPAANIHPIPTELGP-----EDAAAAYEKELRALFGG-----VPPFDLVLLGMGPDGHTASLFPGHPAlLEET 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2404076212 174 ERTVVGVHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAAGAVGRA-RTLWLL 244
Cdd:cd01400   148 DRLVVAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPgEVLWFL 219
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 36-255 8.50e-37

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 131.13  E-value: 8.50e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  36 RGHASVVLTGGrNGNGLLAALASSPARDAIDWGRLDLWWGDERFLPEGDPDRNVTQAREALLDAVPLDPERVHAMPASdg 115
Cdd:PLN02360   41 RGVFAIALSGG-SLISFMGKLCEAPYNKTVDWAKWYIFWADERVVAKNHADSNYKLAKDGLLSKVPVVPSHVYSINDT-- 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 116 pygSDVDAAAEAYA---QEL--ARAAGPESHAAVPSFDVLLLGVGPDTHVASLFPELPAVRETERTVVGVHGSPKPPPTR 190
Cdd:PLN02360  118 ---VTAEEAATDYEfaiRQLvkTRTIGVSDISDCPKFDLILLGMGSDGHVASLFPNHPALEEKDDWVTFITDSPKPPPER 194

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 191 VTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGE-IQAPA--AGAV--GRARTLWLLDSAAASQLPRS 255
Cdd:PLN02360  195 ITFTLPVINSASNVAVVATGESKANAVHLAIDDVTEgPDAPSlpARMVqpTKGKLVWFLDKPAASKLDGF 264
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 15-252 1.41e-21

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 89.85  E-value: 1.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  15 ELMAEAAAARLITKVvdaqTSRGHASVVLTGGRNGNGLLAALASSPARDAIDWGR-----LDLWWGderfLPEGDPDRNV 89
Cdd:cd01399     1 EEMSEAAAELIAELI----REKPPAVLGLATGSTPLGVYEELIELHKEGGLSFSNvttfnLDEYVG----LPPDHPQSYH 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  90 TQAREALLDAVPLDPERVHaMPasDGpYGSDVDAAAEAYAQELARAAGpeshaavpsFDVLLLGVGPDTHVA------SL 163
Cdd:cd01399    73 YFMRENLFDHIDIKPENIH-IP--DG-NAADLEAECRRYEALIAEAGG---------IDLQLLGIGENGHIGfnepgsSL 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 164 FPELPAVRETERTV---VGVHGSPKPPPTR-VTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAAgAVGRAR 239
Cdd:cd01399   140 DSRTRVVTLDESTRqanARFFDGDEDVPTQaITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPAS-ILQLHP 218

                         250
                  ....*....|....*
gi 2404076212 240 --TLWlLDSAAASQL 252
Cdd:cd01399   219 nvTVI-LDEAAASEL 232
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 8-252 9.50e-19

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 82.96  E-value: 9.50e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212   8 LVVHRDKELMAEAAAARLITKVVDAQTSRGHASVVL--TGGrNGNGLLAALASSPARDAIDWGRLDLWWGDERF-LPEGD 84
Cdd:PRK00443    3 LIILKTAEEVGKWAARHIANRINAFLPTKERPFVLGlaTGS-SPLETYKALIELHKAGKVDFSRVTTFNLDEYVgLPADH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  85 PDRNVTQAREALLDAVPLDPERVHaMPASDGPygsDVDAAAEAYAQELARAAGPeshaavpsfDVLLLGVGPDTHVAslF 164
Cdd:PRK00443   82 PESYRYFMRENFFDHVDIPPENIN-LLNGNAP---DPEAECRRYEEKIKSAGGI---------DLQILGIGENGHIA--F 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 165 PELPA--------VRETERTVV---GVHGSP--KPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPA 231
Cdd:PRK00443  147 NEPGSsfasrtriKTLTEDTRIansRFFDGDieQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMWPA 226

                         250       260
                  ....*....|....*....|.
gi 2404076212 232 AGAVGRARTLWLLDSAAASQL 252
Cdd:PRK00443  227 SILQLHPKATLVLDEAAASEL 247
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 76-258 1.97e-09

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 57.73  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  76 DERF-LPEGDPDRNVTQAREALLDAVPLDPERVHAmpasdgPYGS----DVDAAAEAYAQELARAAGpeshaavpsFDVL 150
Cdd:PRK02122   98 DEYYpMQPDSLQSYHRFMKENLFDHVDIPPENIHI------PDGTipkeEIDEYCRDYEEKIEAAGG---------IDFQ 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 151 LLGVGPDTHVAslFPElPAVRETERT--VVGVH-----------GSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAA 217
Cdd:PRK02122  163 LLGIGRTGHIG--FNE-PGSGRNSRTrlVTLDHitrrdaasdffGEENVPRKAITMGVGTILKARRIVLLAWGEHKAPII 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2404076212 218 AIALSGAGEIQAPAAGAVGRARTLWLLDSAAASQLPRSLYP 258
Cdd:PRK02122  240 KRAVEGEISDEVPASYLQEHPNATFVLDLAAASELTRIKTP 280
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 94-252 1.12e-05

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 45.52  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  94 EALLDAVPLDPERVHAMPASdgpyGSDVDAAAEAYAQELaRAAGPeshaavpsFDVLLLGVGPDTHVAslFPELPAVRET 173
Cdd:PTZ00285   91 ENFFDHVDIKEENRHILNGT----APDLEEECRRYEEKI-RAVGG--------IDLFLAGIGTDGHIA--FNEPGSSLDS 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 174 ERTVVGVHGSP-------------KPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAAGAVGRART 240
Cdd:PTZ00285  156 RTRVKSLNQETidanarffgndisKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGGVTHMCPASALQMHPAA 235

                         170
                  ....*....|..
gi 2404076212 241 LWLLDSAAASQL 252
Cdd:PTZ00285  236 VLCLDEDATLEL 247
PRK09762 PRK09762
galactosamine-6-phosphate isomerase; Provisional
 10-243 2.02e-05

galactosamine-6-phosphate isomerase; Provisional


Pssm-ID: 182064  Cd Length: 232  Bit Score: 44.44  E-value: 2.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  10 VHRDKELMAEAAAARLITKVvdaqTSRGHASVVLTGGRNGNGLLAALASSPARDAIDWGR-----LDLWWGderfLPEGD 84
Cdd:PRK09762    5 QVENYTALSERASEYLLAVI----RSKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQltfvkLDEWVD----LPLTM 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212  85 PDRNVTQAREALLDAVPLDPERVHampasdgPYGSDVDAAAE-AYAQELARAAGPeshaavpsFDVLLLGVGPDTHVA-- 161
Cdd:PRK09762   77 PGTCETFLQQHIVQPLGLREDQLI-------SFRSEEINETEcERVTNLIARKGG--------LDLCVLGLGKNGHLGln 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2404076212 162 ----SLFPELPAVRETERTVVG--VHGSPKPPPTRVTLTLPAIRAAREVWLLAAGEDKAQAAAIALSGAGEIQAPAAgav 235
Cdd:PRK09762  142 epgeSLQPACHISQLDARTQQHemLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGKQDATERFLTAKVSTAIPAS--- 218


                  ....*...
gi 2404076212 236 grarTLWL 243
Cdd:PRK09762  219 ----FLWL 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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