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Conserved domains on  [gi|2410459173|ref|WP_268426368|]
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ribonuclease YeeF family protein [Bacillus safensis]

Protein Classification

ribonuclease YeeF family protein( domain architecture ID 11475128)

ribonuclease YeeF family protein similar to Bacillus subtilis ribonucleases YobL, YxiD, YxiD, YqcG, and YeeF, which are toxic components of type II toxin-antitoxin (TA) systems, and to Staphylococcus aureus ESAT-6 secretion machinery protein EssD

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YeeF COG5444
Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense ...
3-384 8.16e-83

Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense mechanisms];


:

Pssm-ID: 444195 [Multi-domain]  Cd Length: 366  Bit Score: 262.02  E-value: 8.16e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173   3 KILDAKALTSAMDTRAKHYQELREQMIDLKKALQGVANLGDDFTGKGADNIKSFYKEL-SGNVDMFISFIDKQKAFHEGV 81
Cdd:COG5444     2 KVLDVSSLHTAIDQTIKQLKQLREQFVALKKAVEGIAELDDAFKGKGADAIKAFYQEChLPFLDFWLTFIDSYIAFLKKI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173  82 SGTLDDTSFGGDTFVEEHFLDNAVHMGIKNAKSIVKDQKKALKTIFQDIDHLISLEVFDSQTFDEKIEDAEDERKKTVKE 161
Cdd:COG5444    82 KSALESLEPSENGFISESFLEHELENGLKKAKEITSELTDEINQILASVSDIVSLPKLSDSDFQEQIDKAKKKRDDTVEK 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 162 LRELDQNLKDEYALSETEQQATMALYAEMINATSDGKaISPMNFDKKAYQN----SEIYKAKSDIEKQTAE---YLKIKK 234
Cdd:COG5444   162 LYELDQNQTTELAQLENDLQTMKTYISKLEEATTGGK-ISPTNFNAKAYHNfaeySELHKKAGEIKKQTEDtmmYLALKK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 235 EQEEARKIAKEQEA---LANRPWYEKALDYSGNIVNELTGVNDAKRAATGVDPItgeeltagqrvaaggmaaaGYIPIVG 311
Cdd:COG5444   241 QQEEAREINKLAEEdeiLINRPWYYKAWSTVITFTGEVTGYYDVKRAATGMAAA-------------------GAAPEVG 301
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2410459173 312 WAGRIFKggkavyktsqatsaavravDIYKTSQKSFDALKTSQKGLYGLTATNGFSEAITGRDMFGNKVSKGQ 384
Cdd:COG5444   302 WAGRMVK-------------------LATKGAAKGSKVLKAGKYGGYGLDSANKFKTVKTALAKAGLALAGGV 355
 
Name Accession Description Interval E-value
YeeF COG5444
Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense ...
3-384 8.16e-83

Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 444195 [Multi-domain]  Cd Length: 366  Bit Score: 262.02  E-value: 8.16e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173   3 KILDAKALTSAMDTRAKHYQELREQMIDLKKALQGVANLGDDFTGKGADNIKSFYKEL-SGNVDMFISFIDKQKAFHEGV 81
Cdd:COG5444     2 KVLDVSSLHTAIDQTIKQLKQLREQFVALKKAVEGIAELDDAFKGKGADAIKAFYQEChLPFLDFWLTFIDSYIAFLKKI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173  82 SGTLDDTSFGGDTFVEEHFLDNAVHMGIKNAKSIVKDQKKALKTIFQDIDHLISLEVFDSQTFDEKIEDAEDERKKTVKE 161
Cdd:COG5444    82 KSALESLEPSENGFISESFLEHELENGLKKAKEITSELTDEINQILASVSDIVSLPKLSDSDFQEQIDKAKKKRDDTVEK 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 162 LRELDQNLKDEYALSETEQQATMALYAEMINATSDGKaISPMNFDKKAYQN----SEIYKAKSDIEKQTAE---YLKIKK 234
Cdd:COG5444   162 LYELDQNQTTELAQLENDLQTMKTYISKLEEATTGGK-ISPTNFNAKAYHNfaeySELHKKAGEIKKQTEDtmmYLALKK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 235 EQEEARKIAKEQEA---LANRPWYEKALDYSGNIVNELTGVNDAKRAATGVDPItgeeltagqrvaaggmaaaGYIPIVG 311
Cdd:COG5444   241 QQEEAREINKLAEEdeiLINRPWYYKAWSTVITFTGEVTGYYDVKRAATGMAAA-------------------GAAPEVG 301
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2410459173 312 WAGRIFKggkavyktsqatsaavravDIYKTSQKSFDALKTSQKGLYGLTATNGFSEAITGRDMFGNKVSKGQ 384
Cdd:COG5444   302 WAGRMVK-------------------LATKGAAKGSKVLKAGKYGGYGLDSANKFKTVKTALAKAGLALAGGV 355
LXG pfam04740
LXG domain of WXG superfamily; This domain is present is the N-terminal region of a group of ...
3-203 4.53e-49

LXG domain of WXG superfamily; This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.


Pssm-ID: 428100 [Multi-domain]  Cd Length: 202  Bit Score: 168.20  E-value: 4.53e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173   3 KILDAKALTSAMDTRAKHYQELREQMIDLKKALQGVANLGDDFTGKGADNIKSFYKELSGNV-DMFISFIDKQKAFHEGV 81
Cdd:pfam04740   1 KVLDVSELIEGIDQTISELKELRDQLEKVKKAIEGLANLEDSLKGKGGEAIKNFYSELHLPFlDFLQDFIDEYIEFLEQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173  82 SGTLDDTSFGGDTFVEEHFLDNAVHMGIKNAKSIVKDQKKALKTIFQDIDHLISLEVFDSQTFDEKIEDAEDERKKTVKE 161
Cdd:pfam04740  81 KAALESFEPSSNAFIDESFLEHELENGLKKAKEKTEELTDEINSILASVSDIVSLPKLSDSEVQDSLQKAKKKVKDTIEK 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2410459173 162 LRELDQNLKDEYALSETEQQATMALYAEMINATSDGKAISPM 203
Cdd:pfam04740 161 LYDFDQEQTSELSELEADLQALKTYVSELEEMTSNGKIAITY 202
 
Name Accession Description Interval E-value
YeeF COG5444
Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense ...
3-384 8.16e-83

Predicted ribonuclease, toxin component of the YeeF-YezG toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 444195 [Multi-domain]  Cd Length: 366  Bit Score: 262.02  E-value: 8.16e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173   3 KILDAKALTSAMDTRAKHYQELREQMIDLKKALQGVANLGDDFTGKGADNIKSFYKEL-SGNVDMFISFIDKQKAFHEGV 81
Cdd:COG5444     2 KVLDVSSLHTAIDQTIKQLKQLREQFVALKKAVEGIAELDDAFKGKGADAIKAFYQEChLPFLDFWLTFIDSYIAFLKKI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173  82 SGTLDDTSFGGDTFVEEHFLDNAVHMGIKNAKSIVKDQKKALKTIFQDIDHLISLEVFDSQTFDEKIEDAEDERKKTVKE 161
Cdd:COG5444    82 KSALESLEPSENGFISESFLEHELENGLKKAKEITSELTDEINQILASVSDIVSLPKLSDSDFQEQIDKAKKKRDDTVEK 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 162 LRELDQNLKDEYALSETEQQATMALYAEMINATSDGKaISPMNFDKKAYQN----SEIYKAKSDIEKQTAE---YLKIKK 234
Cdd:COG5444   162 LYELDQNQTTELAQLENDLQTMKTYISKLEEATTGGK-ISPTNFNAKAYHNfaeySELHKKAGEIKKQTEDtmmYLALKK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173 235 EQEEARKIAKEQEA---LANRPWYEKALDYSGNIVNELTGVNDAKRAATGVDPItgeeltagqrvaaggmaaaGYIPIVG 311
Cdd:COG5444   241 QQEEAREINKLAEEdeiLINRPWYYKAWSTVITFTGEVTGYYDVKRAATGMAAA-------------------GAAPEVG 301
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2410459173 312 WAGRIFKggkavyktsqatsaavravDIYKTSQKSFDALKTSQKGLYGLTATNGFSEAITGRDMFGNKVSKGQ 384
Cdd:COG5444   302 WAGRMVK-------------------LATKGAAKGSKVLKAGKYGGYGLDSANKFKTVKTALAKAGLALAGGV 355
LXG pfam04740
LXG domain of WXG superfamily; This domain is present is the N-terminal region of a group of ...
3-203 4.53e-49

LXG domain of WXG superfamily; This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.


Pssm-ID: 428100 [Multi-domain]  Cd Length: 202  Bit Score: 168.20  E-value: 4.53e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173   3 KILDAKALTSAMDTRAKHYQELREQMIDLKKALQGVANLGDDFTGKGADNIKSFYKELSGNV-DMFISFIDKQKAFHEGV 81
Cdd:pfam04740   1 KVLDVSELIEGIDQTISELKELRDQLEKVKKAIEGLANLEDSLKGKGGEAIKNFYSELHLPFlDFLQDFIDEYIEFLEQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2410459173  82 SGTLDDTSFGGDTFVEEHFLDNAVHMGIKNAKSIVKDQKKALKTIFQDIDHLISLEVFDSQTFDEKIEDAEDERKKTVKE 161
Cdd:pfam04740  81 KAALESFEPSSNAFIDESFLEHELENGLKKAKEKTEELTDEINSILASVSDIVSLPKLSDSEVQDSLQKAKKKVKDTIEK 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2410459173 162 LRELDQNLKDEYALSETEQQATMALYAEMINATSDGKAISPM 203
Cdd:pfam04740 161 LYDFDQEQTSELSELEADLQALKTYVSELEEMTSNGKIAITY 202
PT-TG pfam14449
Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could ...
255-328 2.77e-11

Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could function as a linker that links N-terminal secretion-related domain and C-terminal toxin domain. It contains a TG motif.


Pssm-ID: 433960  Cd Length: 68  Bit Score: 59.28  E-value: 2.77e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2410459173 255 YEKALDYSGNIVNELTGVNDAKRAATGVDPITGEELTAGQRVAAGGMAaagyipIVGWAGRIFKGGKAVYKTSQ 328
Cdd:pfam14449   1 EEKALSKVLDFVPEVGGVKDAIEAITGRDPITGEKLSDWDRLLAGAMA------VPGGVGKLGKKGKALVKGLK 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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