|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03903 |
PRK03903 |
transaldolase; Provisional |
52-332 |
1.53e-141 |
|
transaldolase; Provisional
Pssm-ID: 235171 Cd Length: 274 Bit Score: 401.28 E-value: 1.53e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 52 AYGAQKAKFAHKNTKKLYEILAITDIKNAANALLANYAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKV 131
Cdd:PRK03903 1 AYKDEIAKLKGKKAKEIYEELAIKDIKKAADKLLPLYEKPDDGFISIEIDPFLEDDAAGSIEEGKRLYKTIGRPNVMIKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 132 PATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEAIKEGTSefaakfEGTKLPQSVISIFVSRFDRALDEDMKKSGLe 211
Cdd:PRK03903 81 PATKAGYEAMSALMKKGISVNATLIFSPEQAKECAEALNEGLK------KNTKDPKAVISVFVSRFDRLLDPKLAPKNL- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 212 PAKIGIMNATKCYNIIAKENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFIGAK-CEPKTPFSDEE 290
Cdd:PRK03903 154 QAKSGIMNATKCYNQIEQHANKNIRTLFASTGVKGDDLPKDYYIKELLFKNSINTAPLDTIEAFLKDGnTEPKKPLKIEE 233
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2428127549 291 IDKFFADVaQKAGIDMDKIYKKLLKDGLVAFEQAFDEIMTTL 332
Cdd:PRK03903 234 IEAFFKEL-KSHNIDLENTYQKLLKDGLEAFKQAFEDILKSL 274
|
|
| Transaldolase_like |
cd00955 |
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants ... |
9-327 |
2.81e-103 |
|
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants and bacteria. Transaldolase is found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.
Pssm-ID: 188642 [Multi-domain] Cd Length: 338 Bit Score: 306.56 E-value: 2.81e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAKEF-SDFLAKGTFNGATSNPSIFKNAITTSQAYGAQ--KAKFAHKNTKKLYEILAITDIKNAANALL 85
Cdd:cd00955 1 SLWLDNLSRSFIDNGFlKRLIEEQGVVGVTSNPAIFEKAIAGSAAYDDQirALKGQGLDAEAIYEALAIEDIQDACDLLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 86 AN--YAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTA 163
Cdd:cd00955 81 PVyeQTGGNDGYVSLEVSPRLADDTQGTIAEAKRLWKAVGRPNLMIKIPATEAGLPAIEELIAAGISVNVTLIFSLEQYE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 164 KCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALDEDMKKSGLEPA--KIGIMNATKCYN------------IIAK 229
Cdd:cd00955 161 AVAEAYLRGLERRVEGGGDLSQVASVASFFVSRVDTLIDKKLDAPEAKALqgKVAIANAKLAYQeyqekfsgprwaALAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 230 ENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFI-GAKCEPKTPFSDEEIDKFFADVAqKAGIDMDK 308
Cdd:cd00955 241 AGAKPQRLLWASTGVKNPAYPDVLYVEELIGPDTVNTMPDATLKAFAdHGEVRPTLEEGLEEAERVLAELE-RLGIDLDA 319
|
330
....*....|....*....
gi 2428127549 309 IYKKLLKDGLVAFEQAFDE 327
Cdd:cd00955 320 VTEKLLKEGVKKFKDSFEK 338
|
|
| tal_mycobact |
TIGR00876 |
transaldolase, mycobacterial type; This model describes one of three related but easily ... |
8-331 |
8.29e-78 |
|
transaldolase, mycobacterial type; This model describes one of three related but easily separable famiiles of known and putative transaldolases. This family and the family typified by E. coli TalA and TalB both contain experimentally verified examples. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 129954 Cd Length: 350 Bit Score: 241.95 E-value: 8.29e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 8 FSLWCDFIERDFI-AKEFSDFLAKGTFNGATSNPSIFKNAITTSQAYGAQKAKFAHK--NTKKLYEILAITDIKNAANAL 84
Cdd:TIGR00876 3 FSLWCDDIERDFLeNGDFLELIDKGAICGATSNPSIFCEAISEGAFYDAEIAELAAKgaDADAIIETLALDDILQACDAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 85 LANYAKGD--DGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQT 162
Cdd:TIGR00876 83 MPLWEDSDgnDGRISIEIDPFLADDAAKSIDEAIELFKILDRPNLFIKIPASEAGIEAISALLAAGIPVNVTLIFSPKIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 163 AKCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALDEDMKKSGLEPA-----KIGIMNA-------------TKCY 224
Cdd:TIGR00876 163 GEIADALAKEAEKARQAGHSLSKIHAVASFFVSRFDKEIDKLLDKIGSRQAlelqaQAGIANArlayatyrevfedSDCY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 225 NIIAKENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFI-GAKCEPKTPF-SDEEIDKFFaDVAQKA 302
Cdd:TIGR00876 243 RQIKQDAAKLQRPLFASTGVKNNDLADDLYIKALCAKHSINTAPEEAIDAVAdDGNIECDTPLgTASDAEAFF-DELGAH 321
|
330 340
....*....|....*....|....*....
gi 2428127549 303 GIDMDKIYKKLLKDGLVAFEQAFDEIMTT 331
Cdd:TIGR00876 322 GIDLEDTAAKLEEEGLIAFEASFEELLQE 350
|
|
| TAL_FSA |
pfam00923 |
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ... |
10-297 |
8.39e-68 |
|
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.
Pssm-ID: 395737 [Multi-domain] Cd Length: 226 Bit Score: 212.01 E-value: 8.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 10 LWCDFIERDFIAKefsdFLAKGTFNGATSNPSIFKNAITTSQAYGAQkakfahkntkklyeilaITDIKnaanallanya 89
Cdd:pfam00923 1 IWLDTADRDLIKK----LIEEGGIDGVTTNPSIFLKAIEYSALYDEA-----------------IAEIK----------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 90 KGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEAI 169
Cdd:pfam00923 49 EIGDGPVSLEVDPRLADDTEGTIEEARRLIALYGRPNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAEAG 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 170 KegtsefaakfegtklpqSVISIFVSRFDRALDEDMKKSGLEpaKIGIMNATKCYNIIAKENLpfvralfaSTGVKGGEI 249
Cdd:pfam00923 129 A-----------------SVISPFVGRIDDWGDKRLGAALRG--DDGIANAKEIYQIYKKYGW--------STGVLAASF 181
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2428127549 250 PADYYIKELLYPLSVnTAPLDTIKAFigakcepktpFSDEEIDKFFAD 297
Cdd:pfam00923 182 RNVLYVLALAGCDTI-TIPPDTLEAL----------AKDEGVRKFAKD 218
|
|
| TalA |
COG0176 |
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ... |
9-300 |
1.80e-46 |
|
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 439946 [Multi-domain] Cd Length: 214 Bit Score: 156.77 E-value: 1.80e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAKefsdFLAKGTFNGATSNPSIFKNAittsqaygaqkakfAHKNTKKLY-EILAITDiknaanallan 87
Cdd:COG0176 2 KLWLDTADREEIKE----LIDLGGVDGVTTNPSLIAKA--------------GIKDFVEDIrEICDIVD----------- 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 88 yakgddGFISIEVdpsISDDAEAMIKEGKRLYAQIAmPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLE 167
Cdd:COG0176 53 ------GPVSAEV---LATDTEGMIAEARRLAALYR-PNVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLAAE 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 168 AIKegtsefaakfegtklpqSVISIFVSRFDRAlDEDmkksglepakiGIMNATKCYNIIAKENLPfVRALFASTGvkgg 247
Cdd:COG0176 123 AGA-----------------SYVSPFVGRIDDI-GID-----------GIALVREIYQIYKNYGAR-TRILAASFR---- 168
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2428127549 248 eipADYYIKE--LLYPLSVnTAPLDTIKAFIgakcepKTPFSDEEIDKFFADVAQ 300
Cdd:COG0176 169 ---NPLQVLEaaLAGADTV-TIPPAVLEALA------DHPLTDEGIEKFLADWEK 213
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03903 |
PRK03903 |
transaldolase; Provisional |
52-332 |
1.53e-141 |
|
transaldolase; Provisional
Pssm-ID: 235171 Cd Length: 274 Bit Score: 401.28 E-value: 1.53e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 52 AYGAQKAKFAHKNTKKLYEILAITDIKNAANALLANYAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKV 131
Cdd:PRK03903 1 AYKDEIAKLKGKKAKEIYEELAIKDIKKAADKLLPLYEKPDDGFISIEIDPFLEDDAAGSIEEGKRLYKTIGRPNVMIKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 132 PATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEAIKEGTSefaakfEGTKLPQSVISIFVSRFDRALDEDMKKSGLe 211
Cdd:PRK03903 81 PATKAGYEAMSALMKKGISVNATLIFSPEQAKECAEALNEGLK------KNTKDPKAVISVFVSRFDRLLDPKLAPKNL- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 212 PAKIGIMNATKCYNIIAKENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFIGAK-CEPKTPFSDEE 290
Cdd:PRK03903 154 QAKSGIMNATKCYNQIEQHANKNIRTLFASTGVKGDDLPKDYYIKELLFKNSINTAPLDTIEAFLKDGnTEPKKPLKIEE 233
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2428127549 291 IDKFFADVaQKAGIDMDKIYKKLLKDGLVAFEQAFDEIMTTL 332
Cdd:PRK03903 234 IEAFFKEL-KSHNIDLENTYQKLLKDGLEAFKQAFEDILKSL 274
|
|
| Transaldolase_like |
cd00955 |
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants ... |
9-327 |
2.81e-103 |
|
Transaldolase-like proteins from plants and bacteria; Transaldolase-like proteins from plants and bacteria. Transaldolase is found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.
Pssm-ID: 188642 [Multi-domain] Cd Length: 338 Bit Score: 306.56 E-value: 2.81e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAKEF-SDFLAKGTFNGATSNPSIFKNAITTSQAYGAQ--KAKFAHKNTKKLYEILAITDIKNAANALL 85
Cdd:cd00955 1 SLWLDNLSRSFIDNGFlKRLIEEQGVVGVTSNPAIFEKAIAGSAAYDDQirALKGQGLDAEAIYEALAIEDIQDACDLLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 86 AN--YAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTA 163
Cdd:cd00955 81 PVyeQTGGNDGYVSLEVSPRLADDTQGTIAEAKRLWKAVGRPNLMIKIPATEAGLPAIEELIAAGISVNVTLIFSLEQYE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 164 KCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALDEDMKKSGLEPA--KIGIMNATKCYN------------IIAK 229
Cdd:cd00955 161 AVAEAYLRGLERRVEGGGDLSQVASVASFFVSRVDTLIDKKLDAPEAKALqgKVAIANAKLAYQeyqekfsgprwaALAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 230 ENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFI-GAKCEPKTPFSDEEIDKFFADVAqKAGIDMDK 308
Cdd:cd00955 241 AGAKPQRLLWASTGVKNPAYPDVLYVEELIGPDTVNTMPDATLKAFAdHGEVRPTLEEGLEEAERVLAELE-RLGIDLDA 319
|
330
....*....|....*....
gi 2428127549 309 IYKKLLKDGLVAFEQAFDE 327
Cdd:cd00955 320 VTEKLLKEGVKKFKDSFEK 338
|
|
| tal_mycobact |
TIGR00876 |
transaldolase, mycobacterial type; This model describes one of three related but easily ... |
8-331 |
8.29e-78 |
|
transaldolase, mycobacterial type; This model describes one of three related but easily separable famiiles of known and putative transaldolases. This family and the family typified by E. coli TalA and TalB both contain experimentally verified examples. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 129954 Cd Length: 350 Bit Score: 241.95 E-value: 8.29e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 8 FSLWCDFIERDFI-AKEFSDFLAKGTFNGATSNPSIFKNAITTSQAYGAQKAKFAHK--NTKKLYEILAITDIKNAANAL 84
Cdd:TIGR00876 3 FSLWCDDIERDFLeNGDFLELIDKGAICGATSNPSIFCEAISEGAFYDAEIAELAAKgaDADAIIETLALDDILQACDAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 85 LANYAKGD--DGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQT 162
Cdd:TIGR00876 83 MPLWEDSDgnDGRISIEIDPFLADDAAKSIDEAIELFKILDRPNLFIKIPASEAGIEAISALLAAGIPVNVTLIFSPKIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 163 AKCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALDEDMKKSGLEPA-----KIGIMNA-------------TKCY 224
Cdd:TIGR00876 163 GEIADALAKEAEKARQAGHSLSKIHAVASFFVSRFDKEIDKLLDKIGSRQAlelqaQAGIANArlayatyrevfedSDCY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 225 NIIAKENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFI-GAKCEPKTPF-SDEEIDKFFaDVAQKA 302
Cdd:TIGR00876 243 RQIKQDAAKLQRPLFASTGVKNNDLADDLYIKALCAKHSINTAPEEAIDAVAdDGNIECDTPLgTASDAEAFF-DELGAH 321
|
330 340
....*....|....*....|....*....
gi 2428127549 303 GIDMDKIYKKLLKDGLVAFEQAFDEIMTT 331
Cdd:TIGR00876 322 GIDLEDTAAKLEEEGLIAFEASFEELLQE 350
|
|
| PRK03343 |
PRK03343 |
transaldolase; Validated |
9-335 |
6.54e-68 |
|
transaldolase; Validated
Pssm-ID: 235117 Cd Length: 368 Bit Score: 216.99 E-value: 6.54e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAK-EFSDFLAKGTFNGATSNPSIFKNAITTSQAYGAQ--KAKFAHKNTKKLYEILAITDIKNA--ANA 83
Cdd:PRK03343 14 SIWLDDLSRDRLTSgNLARLIDEKGVVGVTSNPAIFQKAIAGGDAYDAQiaELAAAGADVEEAYEELTTADVRNAcdVLR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 84 LLANYAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTA 163
Cdd:PRK03343 94 PVYEATGGVDGRVSIEVSPRLAHDTEATIAEARRLWAAVDRPNLMIKIPATPEGLPAIEALIAEGISVNVTLIFSVERYR 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 164 KCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALDEDMKKSGLEPA-----KIGIMNATKCYNI------------ 226
Cdd:PRK03343 174 AVADAYLRGLEKRLAAGHDLSKIHSVASFFVSRVDTEVDKRLEAIGTDEAlalrgKAAIANARLAYQAyeevfasprwaa 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 227 IAKENLPFVRALFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAFIgAKCEPKTPFSD--EEIDKFFADVAqKAGI 304
Cdd:PRK03343 254 LAAAGARPQRPLWASTGTKNPAYSDTLYVDELVAPDTVNTMPEATLDAFA-DHGEVADTLTGdyEEAQAVLAALA-ALGI 331
|
330 340 350
....*....|....*....|....*....|.
gi 2428127549 305 DMDKIYKKLLKDGLVAFEQAFDEIMTTLEKE 335
Cdd:PRK03343 332 DLDDVTAVLEEEGVDKFEASWNELLASLEAK 362
|
|
| TAL_FSA |
pfam00923 |
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose ... |
10-297 |
8.39e-68 |
|
Transaldolase/Fructose-6-phosphate aldolase; Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA). They both belong to the class I aldolase family. Their protein structures have been revealed.
Pssm-ID: 395737 [Multi-domain] Cd Length: 226 Bit Score: 212.01 E-value: 8.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 10 LWCDFIERDFIAKefsdFLAKGTFNGATSNPSIFKNAITTSQAYGAQkakfahkntkklyeilaITDIKnaanallanya 89
Cdd:pfam00923 1 IWLDTADRDLIKK----LIEEGGIDGVTTNPSIFLKAIEYSALYDEA-----------------IAEIK----------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 90 KGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEAI 169
Cdd:pfam00923 49 EIGDGPVSLEVDPRLADDTEGTIEEARRLIALYGRPNVLIKIPATWEGIKAIKELSAEGINVNVTLIFSLAQALAAAEAG 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 170 KegtsefaakfegtklpqSVISIFVSRFDRALDEDMKKSGLEpaKIGIMNATKCYNIIAKENLpfvralfaSTGVKGGEI 249
Cdd:pfam00923 129 A-----------------SVISPFVGRIDDWGDKRLGAALRG--DDGIANAKEIYQIYKKYGW--------STGVLAASF 181
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2428127549 250 PADYYIKELLYPLSVnTAPLDTIKAFigakcepktpFSDEEIDKFFAD 297
Cdd:pfam00923 182 RNVLYVLALAGCDTI-TIPPDTLEAL----------AKDEGVRKFAKD 218
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
9-333 |
3.22e-62 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 213.29 E-value: 3.22e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAK-EFSDFLAKGTFNGATSNPSIFKNAITTSQAYGAQKAKFAHKNTK---KLYEILAITDIKNAANAL 84
Cdd:PRK09533 13 SVWLDFLARGFIAKgELKRLVEEDGLRGVTSNPAIFEKAIGSSDEYDDAIKAALAEGDRsviELYETLAIEDIQAAADVL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 85 LAN--YAKGDDGFISIEVDPSISDDAEAMIKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQT 162
Cdd:PRK09533 93 RPVydATDGADGFVSLEVSPYLALDTEGTIAEARRLWAAVDRPNLMIKVPATPEGLPAIRQLIAEGINVNVTLLFSQDVY 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 163 AKCLEAIKEGTSEFAAKFEGTKLPQSVISIFVSRFDRALD---EDMKKSGLEPA----------KIGIMNATKCYN---- 225
Cdd:PRK09533 173 EEVAEAYISGLEARAAKGGDPSHVASVASFFVSRIDSAVDkrlDEKIAAANDPAekaalealkgKVAIANAKLAYQrykr 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 226 IIAKENLPFVRA--------LFASTGVKGGEIPADYYIKELLYPLSVNTAPLDTIKAF-----IGAKCEPKTpfsdEEID 292
Cdd:PRK09533 253 LFAGPRWEALAAkgakpqrlLWASTGTKNKAYSDVLYVEELIGPDTVNTMPPATLDAFrdhgkVRATLEEDV----DEAR 328
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2428127549 293 KFFADVAQkAGIDMDKIYKKLLKDGLVAFEQAFDEIMTTLE 333
Cdd:PRK09533 329 AVLADLAE-AGISLDAVTDKLVAEGVQLFADAFDKLLGAVA 368
|
|
| TalA |
COG0176 |
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; ... |
9-300 |
1.80e-46 |
|
Transaldolase/fructose-6-phosphate aldolase [Carbohydrate transport and metabolism]; Transaldolase/fructose-6-phosphate aldolase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 439946 [Multi-domain] Cd Length: 214 Bit Score: 156.77 E-value: 1.80e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 9 SLWCDFIERDFIAKefsdFLAKGTFNGATSNPSIFKNAittsqaygaqkakfAHKNTKKLY-EILAITDiknaanallan 87
Cdd:COG0176 2 KLWLDTADREEIKE----LIDLGGVDGVTTNPSLIAKA--------------GIKDFVEDIrEICDIVD----------- 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 88 yakgddGFISIEVdpsISDDAEAMIKEGKRLYAQIAmPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLE 167
Cdd:COG0176 53 ------GPVSAEV---LATDTEGMIAEARRLAALYR-PNVVIKIPATEEGLKAIEELSAEGIKVNVTLIFSAAQALLAAE 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 168 AIKegtsefaakfegtklpqSVISIFVSRFDRAlDEDmkksglepakiGIMNATKCYNIIAKENLPfVRALFASTGvkgg 247
Cdd:COG0176 123 AGA-----------------SYVSPFVGRIDDI-GID-----------GIALVREIYQIYKNYGAR-TRILAASFR---- 168
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2428127549 248 eipADYYIKE--LLYPLSVnTAPLDTIKAFIgakcepKTPFSDEEIDKFFADVAQ 300
Cdd:COG0176 169 ---NPLQVLEaaLAGADTV-TIPPAVLEALA------DHPLTDEGIEKFLADWEK 213
|
|
| Transaldolase |
cd00439 |
Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose ... |
35-268 |
9.10e-27 |
|
Transaldolase; Transaldolase. Enzymes found in the non-oxidative branch of the pentose phosphate pathway, that catalyze the reversible transfer of a dihydroxyacetone group from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. They are members of the class I aldolases, who are characterized by using a Schiff-base mechanism for stabilization of the reaction intermediates.
Pssm-ID: 188631 [Multi-domain] Cd Length: 252 Bit Score: 106.28 E-value: 9.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 35 GATSNPSIFKNAITTSQAYGAQKAKFAH--KNTKKLYEILAITDIKNAANALLANYAK-GDDGFISIEVDPSISDDAEAM 111
Cdd:cd00439 23 GVTTNPSIIQAAISTSNAYNDQFRTLVEsgKDIESAYWELVVKDIQDACKLFEPIYDQtEADGRVSVEVSARLADDTQGM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 112 IKEGKRLYAQIAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEAikeGTsefaakfegtklpqSVIS 191
Cdd:cd00439 103 VEAAKYLSKVVNRRNIYIKIPATAEGIPAIKDLIAAGISVNVTLIFSIAQYEAVADA---GT--------------SVAS 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2428127549 192 IFVSRFDRALDEDMKKSGLEP-AKIGIMNATKCYNIIaKENLPFVRALFASTGVKGgeipadyYIKELLYPLSVNTAP 268
Cdd:cd00439 166 PFVSRIDTLMDKMLEQIGLDLrGKAGVAQVTLAYKLY-KQKFKKQRVLWASFSDTL-------YVAPLIGCDTVTTMP 235
|
|
| Transaldolase_FSA |
cd00956 |
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; ... |
22-199 |
5.19e-19 |
|
Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea, which are member of the MipB/TalC subfamily of class I aldolases. FSA catalyze an aldol cleavage of fructose 6-phosphate and do not utilize fructose, fructose 1-phosphate, fructose 1,6-phosphate, or dihydroxyacetone phosphate. The enzymes belong to the transaldolase family that serves in transfer reactions in the pentose phosphate cycle, and are more distantly related to fructose 1,6-bisphosphate aldolase.
Pssm-ID: 188643 [Multi-domain] Cd Length: 211 Bit Score: 83.78 E-value: 5.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 22 KEFSDFlakGTFNGATSNPSIFknaittsqaygaqkAKFAHKNTKKLY-EILAITDiknaanallanyakgddGFISIEV 100
Cdd:cd00956 13 KKASET---GLLDGVTTNPSLI--------------AKSGRIDFEAVLkEICEIID-----------------GPVSAQV 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 101 dpsISDDAEAMIKEGKRLYAQIamPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTakcLEAIKEGtsefaAKF 180
Cdd:cd00956 59 ---VSTDAEGMVAEARKLASLG--GNVVVKIPVTEDGLKAIKKLSEEGIKTNVTAIFSAAQA---LLAAKAG-----ATY 125
|
170
....*....|....*....
gi 2428127549 181 egtklpqsvISIFVSRFDR 199
Cdd:cd00956 126 ---------VSPFVGRIDD 135
|
|
| Transaldolase_TalAB |
cd00957 |
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The ... |
26-231 |
2.77e-12 |
|
Transaldolases including both TalA and TalB; Transaldolases including both TalA and TalB. The enzyme catalyses the reversible transfer of a dyhydroxyacetone moiety, derived from fructose-6-phosphate to erythrose-4-phosphate yielding sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate. The catalytic mechanism is similar to other class I aldolases. The enzyme is found in the non-oxidative branch of the pentose phosphate pathway and forms a dimer in solution.
Pssm-ID: 188644 [Multi-domain] Cd Length: 313 Bit Score: 66.49 E-value: 2.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 26 DFLAKGTFNGATSNPSI---------FKNAITTSQAYGAQKAKFAHKNTKKLYEILAI---TDIknaanallanyAKGDD 93
Cdd:cd00957 20 EAIKKFKPQDATTNPSLilaaaklpeYNKLVDEAIAYAKKKGGSDEDQISNALDKLLVnfgTEI-----------LKLIP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 94 GFISIEVDPSISDDAEAMIKEGKR---LYAQIAMPN--VMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEA 168
Cdd:cd00957 89 GRVSTEVDARLSFDTNATIAKARKlikLYEEAGIDKerILIKIAATWEGIQAAKQLEKEGIHCNLTLLFSFAQAVACAEA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2428127549 169 ikegtsefaakfegtklPQSVISIFVSRFdraLDEDMKKSGLEPAKI----GIMNATKCYNIIAKEN 231
Cdd:cd00957 169 -----------------GVTLISPFVGRI---LDWYKKHSGDKAYTAeedpGVASVKKIYNYYKKFG 215
|
|
| PTZ00411 |
PTZ00411 |
transaldolase-like protein; Provisional |
93-231 |
1.01e-10 |
|
transaldolase-like protein; Provisional
Pssm-ID: 240406 Cd Length: 333 Bit Score: 62.06 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 93 DGFISIEVDPSISDDAEAMIKEGKR---LYAQ--IAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLE 167
Cdd:PTZ00411 100 PGRVSTEVDARLSFDKQAMVDKARKiikMYEEagISKDRILIKLASTWEGIQAAKALEKEGIHCNLTLLFSFAQAVACAQ 179
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2428127549 168 AikegtsefaakfeGTKLpqsvISIFVSRFDRALDEDMKKSGLEPAK-IGIMNATKCYNIIAKEN 231
Cdd:PTZ00411 180 A-------------GVTL----ISPFVGRILDWYKKPEKAESYVGAQdPGVISVTKIYNYYKKHG 227
|
|
| PRK05269 |
PRK05269 |
transaldolase B; Provisional |
36-168 |
1.51e-09 |
|
transaldolase B; Provisional
Pssm-ID: 235381 [Multi-domain] Cd Length: 318 Bit Score: 58.25 E-value: 1.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 36 ATSNPSIFKNAITT-------SQAYGAQKAKFAHKNTK------KLY-----EILAITDiknaanallanyakgddGFIS 97
Cdd:PRK05269 32 ATTNPSLILKAAQIpeyapliDDAVAWAKQQSGDRAQQiddaidKLAvnfglEILKLIP-----------------GRVS 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2428127549 98 IEVDPSISDDAEAMIKEGKRL---YAQIAMPN--VMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEA 168
Cdd:PRK05269 95 TEVDARLSFDTEATIAKARKLialYEEAGISKdrILIKIASTWEGIRAAEQLEKEGINCNLTLLFSFAQARACAEA 170
|
|
| PRK12309 |
PRK12309 |
transaldolase; |
94-225 |
8.27e-09 |
|
transaldolase;
Pssm-ID: 183426 [Multi-domain] Cd Length: 391 Bit Score: 56.28 E-value: 8.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 94 GFISIEVDPSISDDAEAMIKEGKRLYAQ-----IAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEA 168
Cdd:PRK12309 95 GRVSTEVDARLSYDTEATIAKARKLISLyedagISRDRVLIKIASTWEGIKAAEVLEKEGIHCNLTLLFGFHQAIACAEA 174
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2428127549 169 ikegtsefaakfeGTKLpqsvISIFVSRFdraLDEDMKKSGLE----PAKIGIMNATKCYN 225
Cdd:PRK12309 175 -------------GVTL----ISPFVGRI---LDWYKKETGRDsypgAEDPGVQSVTQIYN 215
|
|
| PRK12346 |
PRK12346 |
transaldolase A; Provisional |
94-196 |
1.22e-06 |
|
transaldolase A; Provisional
Pssm-ID: 183458 Cd Length: 316 Bit Score: 49.33 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2428127549 94 GFISIEVDPSISDDAEAMIKEGKRL---YAQ--IAMPNVMIKVPATQAGYETMRALTRRGINVNATLIFSPEQTAKCLEA 168
Cdd:PRK12346 90 GRVSTEVDARLSFDREKSIEKARHLvdlYQQqgIDKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEA 169
|
90 100
....*....|....*....|....*...
gi 2428127549 169 ikegtsefaakfeGTKLpqsvISIFVSR 196
Cdd:PRK12346 170 -------------GVFL----ISPFVGR 180
|
|
| |
