NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2442585541|ref|WP_272929861|]
View 

UDP-galactopyranose mutase [Actinobacillus pleuropneumoniae]

Protein Classification

UDP-galactopyranose mutase( domain architecture ID 11426203)

UDP-galactopyranose mutase converts uridine diphosphogalactopyranose (UDP-GalP) to uridine diphosphogalactofuranose (UDP-GalF)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
8-362 0e+00

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 590.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   8 GAGLSCAVIARELAEQ-GYKVTIFEGRNHIAGNCHTQRDEnTGVMVHVYGPHIFHTDNENVWNYVNKYMEFKPYVNRVKS 86
Cdd:COG0562     9 GAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDE-TGILVHKYGPHIFHTNNKRVWDYLSRFTEFNPYQHRVLA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  87 TILGKVYSLPINLHTINQFFGKNLSPKEAKAFIEQQAdMSITDPQSFEEQAMRFVGKDLYEAFFKGYTKKQWGLEPSSLP 166
Cdd:COG0562    88 NVDGQLYPLPFNLNTINQLFGKKLTPDEARAFIAEQA-EPIKEPRNLEEQALSLVGRDLYEKFFKGYTEKQWGRDPSELP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 167 ASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNTLFKRE-QVQHYDHVFYSGTIDGYFNYEFGRL 245
Cdd:COG0562   167 ASIIKRLPVRFNYDNRYFNDTYQGMPKGGYTAMFERMLDHPNIEVRLNTDFFEVrDEIPADHVVYTGPIDEYFDYRFGRL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 246 PYRTLDFK-KYYDEGDFQGCAVMNYGDENIPYTRISEHKHFANWeDHEKTVYFEEYSRQCTPNDIPYYPINLVEGNELIT 324
Cdd:COG0562   247 PYRSLDFEfETLDVEDFQGVAVVNYPDADVPYTRITEFKHFTGQ-QHPKTVITREYPRAYEEGDEPYYPINDEENQALYK 325

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2442585541 325 KYKEKAKREQKVTFVGRLGTFRYLDMDVIIKEALDIAR 362
Cdd:COG0562   326 KYRALAEKEPNVIFGGRLATYRYYDMDQVIASALALFD 363
 
Name Accession Description Interval E-value
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
8-362 0e+00

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 590.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   8 GAGLSCAVIARELAEQ-GYKVTIFEGRNHIAGNCHTQRDEnTGVMVHVYGPHIFHTDNENVWNYVNKYMEFKPYVNRVKS 86
Cdd:COG0562     9 GAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDE-TGILVHKYGPHIFHTNNKRVWDYLSRFTEFNPYQHRVLA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  87 TILGKVYSLPINLHTINQFFGKNLSPKEAKAFIEQQAdMSITDPQSFEEQAMRFVGKDLYEAFFKGYTKKQWGLEPSSLP 166
Cdd:COG0562    88 NVDGQLYPLPFNLNTINQLFGKKLTPDEARAFIAEQA-EPIKEPRNLEEQALSLVGRDLYEKFFKGYTEKQWGRDPSELP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 167 ASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNTLFKRE-QVQHYDHVFYSGTIDGYFNYEFGRL 245
Cdd:COG0562   167 ASIIKRLPVRFNYDNRYFNDTYQGMPKGGYTAMFERMLDHPNIEVRLNTDFFEVrDEIPADHVVYTGPIDEYFDYRFGRL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 246 PYRTLDFK-KYYDEGDFQGCAVMNYGDENIPYTRISEHKHFANWeDHEKTVYFEEYSRQCTPNDIPYYPINLVEGNELIT 324
Cdd:COG0562   247 PYRSLDFEfETLDVEDFQGVAVVNYPDADVPYTRITEFKHFTGQ-QHPKTVITREYPRAYEEGDEPYYPINDEENQALYK 325

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2442585541 325 KYKEKAKREQKVTFVGRLGTFRYLDMDVIIKEALDIAR 362
Cdd:COG0562   326 KYRALAEKEPNVIFGGRLATYRYYDMDQVIASALALFD 363
GLF pfam03275
UDP-galactopyranose mutase;
148-347 1.28e-105

UDP-galactopyranose mutase;


Pssm-ID: 427229  Cd Length: 203  Bit Score: 308.70  E-value: 1.28e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 148 AFFKGYTKKQWGLEPSSLPASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNTLF---KREQVQH 224
Cdd:pfam03275   1 KFFKGYTEKQWGLDPEELPASVIKRLPVRFNYDNRYFNDTYQGLPKDGYTKMFENMLDHPNIEVRLNTDFfdiRDNDVEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 225 YDHVFYSGTIDGYFNYEFGRLPYRTLDFKKY-YDEGDFQGCAVMNYGDENIPYTRISEHKHFANWEdHEKTVYFEEYSRQ 303
Cdd:pfam03275  81 ADPVVYTGPIDEYFDYCFGELPYRSLDFETEtLDQGDFQGNAVVNYPDDEVPYTRITEYKHFTPQK-HDKTVITREYPRA 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2442585541 304 CTPNDIPYYPINLVEGNELITKYKEKAKREQKVTFVGRLGTFRY 347
Cdd:pfam03275 160 WEEGDEPYYPINTEENRALYEKYRELAKKEPNVTFGGRLGTYRY 203
UDP-GALP_mutase TIGR00031
UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into ...
 1-362 1.37e-99

UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into UDP-GALF through a 2-keto intermediate. It contains FAD as a cofactor. The gene is known as glf, ceoA, and rfbD. It is known experimentally in E. coli, Mycobacterium tuberculosis, and Klebsiella pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 272864 [Multi-domain]  Cd Length: 377  Bit Score: 299.77  E-value: 1.37e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   1 MKNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDENtgVMVHVYGPHIFHTDNENVWNYVNKYMEFKPY 80
Cdd:TIGR00031   1 MFDYIIVGAGLSGIVLANILAQLNKRVLVVEKRNHIGGNCYDEVDET--ILFHQYGPHIFHTNNQYVWDYISPFFELNNY 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  81 VNRVKSTILGKVYSLPINLHTINQFFGKNLsPKEAKAFIEQQ----ADMSITDPQSFEEQAMRFVGKDLYEAFFKGYTKK 156
Cdd:TIGR00031  79 QHRVLALYNNLDLTLPFNFNQFRKLLGVKD-AQELQNFFNAQfkygDHVPLEELQEIADPDIQLLYQFLYQKVYKPYTVK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 157 QWGLEPSSLPASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNT-----LFKREQV-----QHYD 226
Cdd:TIGR00031 158 QWGLPAEEIDPFVIGRVPVVLSEDSSYFPDRYQGLPKGGYTKLFEKMLDHPLIDVKLNChinllKDKDSQLhfankAIRK 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 227 HVFYSGTIDGYFNYEFGRLPYRTLDFK-KYYDEGDFQGCAVMNYgDENIPYTRISEHKHFANwEDHEKTVYFEEYSRQCT 305
Cdd:TIGR00031 238 PVIYTGLIDQLFGYRFGALQYRSLKFEwERHEFKNFQGYAVVNF-PLNVPITRIVEYKHLTY-VGSKQTIVSKEYPGEWK 315

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2442585541 306 PNDI-PYYPINLVEGNELITKYKEKAKREQKVTFVGRLGTFRYLDMDVIIKEALDIAR 362
Cdd:TIGR00031 316 VGDPePYYPVNDNKNMALFKKYLELASREDNLILLGRLAEYQYYDMDQAILAALYKAE 373
PRK07208 PRK07208
hypothetical protein; Provisional
 1-167 1.89e-14

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 74.16  E-value: 1.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   1 MKNIAMAG---AGLSCAViarELAEQGYKVTIFEGRNHIAGNCHTQRDEntGVMVHvYGPHIFHTDNENVWNYVNKYMEF 77
Cdd:PRK07208    4 KKSVVIIGagpAGLTAAY---ELLKRGYPVTVLEADPVVGGISRTVTYK--GNRFD-IGGHRFFSKSPEVMDLWNEILPD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  78 KPYVNRV-KSTIL--GKVYSLPI-NLHTInqffgKNLSPKEA----KAFIEQQAdMSITDPQSFEE-QAMRFvGKDLYEA 148
Cdd:PRK07208   78 DDFLLRPrLSRIYyrGKFFDYPLkAFDAL-----KNLGLWRTakcgASYLKARL-RPRKEEDSFEDwVINRF-GRRLYST 150

                         170
                  ....*....|....*....
gi 2442585541 149 FFKGYTKKQWGLEPSSLPA 167
Cdd:PRK07208  151 FFKGYTEKVWGVPCDEISA 169
 
Name Accession Description Interval E-value
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
8-362 0e+00

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 590.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   8 GAGLSCAVIARELAEQ-GYKVTIFEGRNHIAGNCHTQRDEnTGVMVHVYGPHIFHTDNENVWNYVNKYMEFKPYVNRVKS 86
Cdd:COG0562     9 GAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDE-TGILVHKYGPHIFHTNNKRVWDYLSRFTEFNPYQHRVLA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  87 TILGKVYSLPINLHTINQFFGKNLSPKEAKAFIEQQAdMSITDPQSFEEQAMRFVGKDLYEAFFKGYTKKQWGLEPSSLP 166
Cdd:COG0562    88 NVDGQLYPLPFNLNTINQLFGKKLTPDEARAFIAEQA-EPIKEPRNLEEQALSLVGRDLYEKFFKGYTEKQWGRDPSELP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 167 ASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNTLFKRE-QVQHYDHVFYSGTIDGYFNYEFGRL 245
Cdd:COG0562   167 ASIIKRLPVRFNYDNRYFNDTYQGMPKGGYTAMFERMLDHPNIEVRLNTDFFEVrDEIPADHVVYTGPIDEYFDYRFGRL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 246 PYRTLDFK-KYYDEGDFQGCAVMNYGDENIPYTRISEHKHFANWeDHEKTVYFEEYSRQCTPNDIPYYPINLVEGNELIT 324
Cdd:COG0562   247 PYRSLDFEfETLDVEDFQGVAVVNYPDADVPYTRITEFKHFTGQ-QHPKTVITREYPRAYEEGDEPYYPINDEENQALYK 325

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2442585541 325 KYKEKAKREQKVTFVGRLGTFRYLDMDVIIKEALDIAR 362
Cdd:COG0562   326 KYRALAEKEPNVIFGGRLATYRYYDMDQVIASALALFD 363
GLF pfam03275
UDP-galactopyranose mutase;
148-347 1.28e-105

UDP-galactopyranose mutase;


Pssm-ID: 427229  Cd Length: 203  Bit Score: 308.70  E-value: 1.28e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 148 AFFKGYTKKQWGLEPSSLPASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNTLF---KREQVQH 224
Cdd:pfam03275   1 KFFKGYTEKQWGLDPEELPASVIKRLPVRFNYDNRYFNDTYQGLPKDGYTKMFENMLDHPNIEVRLNTDFfdiRDNDVEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 225 YDHVFYSGTIDGYFNYEFGRLPYRTLDFKKY-YDEGDFQGCAVMNYGDENIPYTRISEHKHFANWEdHEKTVYFEEYSRQ 303
Cdd:pfam03275  81 ADPVVYTGPIDEYFDYCFGELPYRSLDFETEtLDQGDFQGNAVVNYPDDEVPYTRITEYKHFTPQK-HDKTVITREYPRA 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2442585541 304 CTPNDIPYYPINLVEGNELITKYKEKAKREQKVTFVGRLGTFRY 347
Cdd:pfam03275 160 WEEGDEPYYPINTEENRALYEKYRELAKKEPNVTFGGRLGTYRY 203
UDP-GALP_mutase TIGR00031
UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into ...
 1-362 1.37e-99

UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into UDP-GALF through a 2-keto intermediate. It contains FAD as a cofactor. The gene is known as glf, ceoA, and rfbD. It is known experimentally in E. coli, Mycobacterium tuberculosis, and Klebsiella pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 272864 [Multi-domain]  Cd Length: 377  Bit Score: 299.77  E-value: 1.37e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   1 MKNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDENtgVMVHVYGPHIFHTDNENVWNYVNKYMEFKPY 80
Cdd:TIGR00031   1 MFDYIIVGAGLSGIVLANILAQLNKRVLVVEKRNHIGGNCYDEVDET--ILFHQYGPHIFHTNNQYVWDYISPFFELNNY 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  81 VNRVKSTILGKVYSLPINLHTINQFFGKNLsPKEAKAFIEQQ----ADMSITDPQSFEEQAMRFVGKDLYEAFFKGYTKK 156
Cdd:TIGR00031  79 QHRVLALYNNLDLTLPFNFNQFRKLLGVKD-AQELQNFFNAQfkygDHVPLEELQEIADPDIQLLYQFLYQKVYKPYTVK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 157 QWGLEPSSLPASILKRLPVRFNYDDNYFAHRFQGMPAEGYTKMVENILNHSNITVHLNT-----LFKREQV-----QHYD 226
Cdd:TIGR00031 158 QWGLPAEEIDPFVIGRVPVVLSEDSSYFPDRYQGLPKGGYTKLFEKMLDHPLIDVKLNChinllKDKDSQLhfankAIRK 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 227 HVFYSGTIDGYFNYEFGRLPYRTLDFK-KYYDEGDFQGCAVMNYgDENIPYTRISEHKHFANwEDHEKTVYFEEYSRQCT 305
Cdd:TIGR00031 238 PVIYTGLIDQLFGYRFGALQYRSLKFEwERHEFKNFQGYAVVNF-PLNVPITRIVEYKHLTY-VGSKQTIVSKEYPGEWK 315

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2442585541 306 PNDI-PYYPINLVEGNELITKYKEKAKREQKVTFVGRLGTFRYLDMDVIIKEALDIAR 362
Cdd:TIGR00031 316 VGDPePYYPVNDNKNMALFKKYLELASREDNLILLGRLAEYQYYDMDQAILAALYKAE 373
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-74 1.62e-16

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 73.33  E-value: 1.62e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2442585541   8 GAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDENtgvMVHVYGPHIFHTDNE-NVWNYVNKY 74
Cdd:pfam13450   3 GAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPG---YVFDYGAHIFHGSDEpNVRDLLDEL 67
PRK07208 PRK07208
hypothetical protein; Provisional
 1-167 1.89e-14

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 74.16  E-value: 1.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   1 MKNIAMAG---AGLSCAViarELAEQGYKVTIFEGRNHIAGNCHTQRDEntGVMVHvYGPHIFHTDNENVWNYVNKYMEF 77
Cdd:PRK07208    4 KKSVVIIGagpAGLTAAY---ELLKRGYPVTVLEADPVVGGISRTVTYK--GNRFD-IGGHRFFSKSPEVMDLWNEILPD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  78 KPYVNRV-KSTIL--GKVYSLPI-NLHTInqffgKNLSPKEA----KAFIEQQAdMSITDPQSFEE-QAMRFvGKDLYEA 148
Cdd:PRK07208   78 DDFLLRPrLSRIYyrGKFFDYPLkAFDAL-----KNLGLWRTakcgASYLKARL-RPRKEEDSFEDwVINRF-GRRLYST 150

                         170
                  ....*....|....*....
gi 2442585541 149 FFKGYTKKQWGLEPSSLPA 167
Cdd:PRK07208  151 FFKGYTEKVWGVPCDEISA 169
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-174 1.75e-12

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 68.32  E-value: 1.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   1 MKNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDEntGVMVHvYGPHIFHTDNEnvwnYVNKYM----- 75
Cdd:COG1232     1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVD--GFRID-RGPHSFLTRDP----EVLELLrelgl 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  76 --EFKpYVNRVKSTIL--GKVYSLPINlhTINQFFGKNLSPKE-AKAFIEQQA-DMSITDPQSFEEQAMRFVGKDLYEAF 149
Cdd:COG1232    74 gdELV-WPNTRKSYIYygGKLHPLPQG--PLALLRSPLLSLAGkLRALLELLApRRPPGEDESLAEFVRRRFGREVYERL 150

                         170       180
                  ....*....|....*....|....*.
gi 2442585541 150 FKGYTKKQWGLEPSSLPA-SILKRLP 174
Cdd:COG1232   151 VEPLLEGVYAGDPDELSAdWAFPRLK 176
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 9-215 6.90e-11

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 63.28  E-value: 6.90e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   9 AGLSCAviaRELAEQGYKVTIFEGRNHIAGNCHTQRDEntGVMVHVyGPHIFHTDNENVWNYVNKY-ME----------F 77
Cdd:pfam01593   2 AGLAAA---RELLRAGHDVTVLEARDRVGGRIRTVRDD--GFLIEL-GAMWFHGAQPPLLALLKELgLEdrlvlpdpapF 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  78 KPYVNRVKSTILGKVYSLPINLHTINQFFGKNLSPKEAKAFIEQQA----DMSITDPQSFEEQAMRFVGKDLYEAFFKGY 153
Cdd:pfam01593  76 YTVLFAGGRRYPGDFRRVPAGWEGLLEFGRLLSIPEKLRLGLAALAsdalDEFDLDDFSLAESLLFLGRRGPGDVEVWDR 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2442585541 154 TKKQWGLEPSSLPASILKRLPVRFN----YDDNYFAHRFQG---MPAEGYTKMVENIlnHSNI---TVHLNT 215
Cdd:pfam01593 156 LIDPELFAALPFASGAFAGDPSELSaglaLPLLWALLGEGGsllLPRGGLGALPDAL--AAQLlggDVRLNT 225
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
7-89 1.40e-10

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 62.25  E-value: 1.40e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   7 AG-AGLSCAviaRELAEQGYKVTIFEGRNHIAGNCHTQRDENTGVMVHVyGPHIFHTDNENVWNYVNKY-MEFKPYVNRV 84
Cdd:COG1231    15 AGlAGLAAA---RELRKAGLDVTVLEARDRVGGRVWTLRFGDDGLYAEL-GAMRIPPSHTNLLALARELgLPLEPFPNEN 90


                  ....*
gi 2442585541  85 KSTIL 89
Cdd:COG1231    91 GNALL 95
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-60 1.01e-06

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 50.24  E-value: 1.01e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2442585541   1 MKNIAMAG---AGLSCAViarELAEQGYKVTIFEGRNHIAGNCHTQRDENTGvMVHVYGPHIF 60
Cdd:COG3349     3 PPRVVVVGgglAGLAAAV---ELAEAGFRVTLLEARPRLGGRARSFPDPDTG-LPIDNGQHVL 61
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 2-56 5.37e-05

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 44.78  E-value: 5.37e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2442585541   2 KNIAMAG---AGLSCAviaRELAEQGYKVTIFEgRNHIAGnchtqrdentGVMvhVYG 56
Cdd:PRK11749  141 KKVAVIGagpAGLTAA---HRLARKGYDVTIFE-ARDKAG----------GLL--RYG 182
PLN02487 PLN02487
zeta-carotene desaturase
 4-60 5.98e-05

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 44.79  E-value: 5.98e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2442585541   4 IAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDENTGvmvHV-YGPHIF 60
Cdd:PLN02487   78 VAIIGAGLAGMSTAVELLDQGHEVDIYESRPFIGGKVGSFVDKNGN---HIeMGLHVF 132
PLN03000 PLN03000
amine oxidase
 2-46 1.15e-04

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 44.24  E-value: 1.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2442585541   2 KNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDE 46
Cdd:PLN03000  185 SSVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKME 229
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 7-80 1.36e-04

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 43.68  E-value: 1.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   7 AG-AGLSCAVIareLAEQGYKVTIFEGRNHIAGNCHT-QRDE---NTGVMVHVYgPHIFhtdnENVWNYVNK--YMEFKP 79
Cdd:COG1233    11 AGiGGLAAAAL---LARAGYRVTVLEKNDTPGGRARTfERPGfrfDVGPSVLTM-PGVL----ERLFRELGLedYLELVP 82


                  .
gi 2442585541  80 Y 80
Cdd:COG1233    83 L 83
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 3-50 2.72e-04

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 43.06  E-value: 2.72e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2442585541   3 NIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDENTGV 50
Cdd:PLN02328  240 NVVVVGAGLAGLVAARQLLSMGFKVVVLEGRARPGGRVKTMKMKGDGV 287
PRK07233 PRK07233
hypothetical protein; Provisional
 3-290 4.09e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 42.18  E-value: 4.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541   3 NIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQRDEntGVMVHVYGPHIFHTDnENVWNYVN-----KYMEF 77
Cdd:PRK07233    1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFG--GLPIERFYHHIFKSD-EALLELLDelgleDKLRW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541  78 KP-----YVNrvkstilGKVYSL--PINLHTinqFFGKNLSPKEAKAFIEQQADmSITDPQSFE-----EQAMRFVGKDL 145
Cdd:PRK07233   78 REtktgyYVD-------GKLYPLgtPLELLR---FPHLSLIDKFRLGLLTLLAR-RIKDWRALDkvpaeEWLRRWSGEGV 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 146 YEAFFKGYTKKQWGLEPSSLPAS-ILKRLPVRFNYDDNYFAHRFqGMPAEGYT----KMVENILNHsNITVHLNTLFKR- 219
Cdd:PRK07233  147 YEVFWEPLLESKFGDYADDVSAAwLWSRIKRRGNRRYSLFGEKL-GYLEGGFAtlidALAEAIEAR-GGEIRLGTPVTSv 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2442585541 220 -------------EQVQHYDHVFYSGTIDgyfnyEFGRL-PYRTLDFKKYYDEGDFQGCAVM--------------NYGD 271
Cdd:PRK07233  225 vidgggvtgvevdGEEEDFDAVISTAPPP-----ILARLvPDLPADVLARLRRIDYQGVVCMvlklrrpltdyywlNIND 299

                         330
                  ....*....|....*....
gi 2442585541 272 ENIPYTRISEHKHFANWED 290
Cdd:PRK07233  300 PGAPFGGVIEHTNLVPPER 318
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 2-38 8.04e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 41.27  E-value: 8.04e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2442585541   2 KNIAMAG---AGLSCAviaRELAEQGYKVTIFEgRNHIAG 38
Cdd:COG0493   122 KKVAVVGsgpAGLAAA---YQLARAGHEVTVFE-ALDKPG 157
PLN02976 PLN02976
amine oxidase
 2-44 1.77e-03

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 40.62  E-value: 1.77e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2442585541    2 KNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQR 44
Cdd:PLN02976   694 KKIIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDR 736
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 1-31 2.08e-03

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 40.01  E-value: 2.08e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2442585541   1 MKNIAMAGAGLSCAVIARELAEQGYKVTIFE 31
Cdd:PRK12409    1 MSHIAVIGAGITGVTTAYALAQRGYQVTVFD 31
PLN02529 PLN02529
lysine-specific histone demethylase 1
 2-44 4.51e-03

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 39.10  E-value: 4.51e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2442585541   2 KNIAMAGAGLSCAVIARELAEQGYKVTIFEGRNHIAGNCHTQR 44
Cdd:PLN02529  161 GSVIIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQK 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH