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Conserved domains on  [gi|2443491674|ref|WP_273132363|]
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TonB-dependent siderophore receptor [Marinobacter vinifirmus]

Protein Classification

TonB-dependent receptor plug domain-containing protein( domain architecture ID 11469150)

TonB-dependent receptor plug domain-containing protein may act as a TonB-dependent siderophore receptor, a channel to allow import of iron-siderophore complexes; similar to Escherichia coli ferrienterobactin receptor, which is involved in the initial step of iron uptake by binding ferrienterobactin

Gene Ontology:  GO:0015891|GO:0055085|GO:0015267|GO:0016020|GO:0009279
PubMed:  12409204|32355044|9886293|15111112

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 29-587 5.97e-62

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


:

Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 218.19  E-value: 5.97e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVT--TYHGtvhYEQRRMQVLVDGRTA 106
Cdd:COG4771    31 VVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRGGSSgiSIRG---LGGDRVLVLIDGVPV 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLSDMdWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVGHTGS- 185
Cdd:COG4771   108 NNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTYSGSLSLGGPg 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 186 -DYDWRLTYEKRKFDGFDYQIEGDEQVPfyDGHDINSFTYDSRLQINSQADLEFRGGVVDGTNYQDRFKSGDLEPLENPD 264
Cdd:COG4771   187 dKLSFLLSGSYRDRDGYLDYRNGGFVGN--SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNA 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 265 ieVRDFYLQTRFNYATSDRHFFhiqaavenfdrrqayavsfpdntaqclrdGTPLYQYTYFDNGDDRerlcfTSSGGEMA 344
Cdd:COG4771   265 --GDRDTTTDRGNYSLRYNGDL-----------------------------GDNLDLSLYYSRTDRD-----STNGSLGG 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 345 FTTVNANSEDTRLEFELQDTLLFSDNLKLVSGAGFRKDTYRSETYFNGRGNSYQS-RYFGNLEYTPISFMTLNAGGNWEH 423
Cdd:COG4771   309 STGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDLDSSSFLGGADASRDTyGLFAQDEWKLTDKLTLTAGLRYDY 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 424 TSTTDEG---YFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPAiysdlegfrvdtyaaaedldvl 500
Cdd:COG4771   389 YSTFGASnytAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYVLG---------------------- 446

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 501 tlGKDLQEERITSREISYFGQFPMDSalFSLEVRGFKDELRDMISGVIQLKE----WTIDNNVAVDQKGFEVEASLDF-P 575
Cdd:COG4771   447 --NPDLKPETSDNYELGLEYRLGNGG--LSLSLTGFYTDIKDLIVLVPVGPGpgdvLQYENVGKARTYGLELELKYRLgK 522

                         570
                  ....*....|..
gi 2443491674 576 GTTLRASYGYLD 587
Cdd:COG4771   523 GLTLTASYTYLD 534
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 29-587 5.97e-62

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 218.19  E-value: 5.97e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVT--TYHGtvhYEQRRMQVLVDGRTA 106
Cdd:COG4771    31 VVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRGGSSgiSIRG---LGGDRVLVLIDGVPV 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLSDMdWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVGHTGS- 185
Cdd:COG4771   108 NNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTYSGSLSLGGPg 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 186 -DYDWRLTYEKRKFDGFDYQIEGDEQVPfyDGHDINSFTYDSRLQINSQADLEFRGGVVDGTNYQDRFKSGDLEPLENPD 264
Cdd:COG4771   187 dKLSFLLSGSYRDRDGYLDYRNGGFVGN--SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNA 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 265 ieVRDFYLQTRFNYATSDRHFFhiqaavenfdrrqayavsfpdntaqclrdGTPLYQYTYFDNGDDRerlcfTSSGGEMA 344
Cdd:COG4771   265 --GDRDTTTDRGNYSLRYNGDL-----------------------------GDNLDLSLYYSRTDRD-----STNGSLGG 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 345 FTTVNANSEDTRLEFELQDTLLFSDNLKLVSGAGFRKDTYRSETYFNGRGNSYQS-RYFGNLEYTPISFMTLNAGGNWEH 423
Cdd:COG4771   309 STGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDLDSSSFLGGADASRDTyGLFAQDEWKLTDKLTLTAGLRYDY 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 424 TSTTDEG---YFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPAiysdlegfrvdtyaaaedldvl 500
Cdd:COG4771   389 YSTFGASnytAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYVLG---------------------- 446

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 501 tlGKDLQEERITSREISYFGQFPMDSalFSLEVRGFKDELRDMISGVIQLKE----WTIDNNVAVDQKGFEVEASLDF-P 575
Cdd:COG4771   447 --NPDLKPETSDNYELGLEYRLGNGG--LSLSLTGFYTDIKDLIVLVPVGPGpgdvLQYENVGKARTYGLELELKYRLgK 522

                         570
                  ....*....|..
gi 2443491674 576 GTTLRASYGYLD 587
Cdd:COG4771   523 GLTLTASYTYLD 534
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 45-587 2.79e-26

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 114.47  E-value: 2.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  45 STTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTY-HGTVHYEQRrmqVLVDGRTAHRATLSDMdWETMPVPL 123
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISiRGFGPDRTL---VLVDGLPLASSNYGRG-VDLNTIPP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 124 EMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGS-------RGHLRTFGSVGHTGSdYDWRLTYEKR 196
Cdd:cd01347    77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdnsgssgGGGFDVSGALADDGA-FGARLYGAYR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 197 KFDGFDYQIEGDEQVpFYDGHDIN-SFTYdsrlQINSQADLEFRGGVVDGTNYQD-RFKSGDLEPLENPDIEVRDFYLQT 274
Cdd:cd01347   156 DGDGTIDGDGQADDS-DEERYNVAgKLDW----RPDDDTRLTLDAGYQDQDADGPgGTLPANGTGSSLGGGPSSNTNGDR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 275 RFNYATSDRHFFHIQAAVENFDRRQAYAVSFPDNTAQclRDGTPLYQYTYFDNGDDRERLCFTSSGGEmafttVNANSED 354
Cdd:cd01347   231 DWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTD--NDGDPLILNGGNNAAGGDLGRSGYSSERD-----TTQLGFD 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 355 TRLEFELQDtllFSDNLKLVSGAGFRKDTYrsetyfngrgNSYQSRYFGNLEYTPISFMTLNAGGNWEHTSTTDEGY--- 431
Cdd:cd01347   304 AGLNAPFGT---GPVAHTLTLGVEYRREEL----------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTiag 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 432 ----------FSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPaiysdlegfrvdtyaaaedldvlt 501
Cdd:cd01347   371 gttakksyshWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVG------------------------ 426

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 502 lGKDLQEERITSREISYFGQFPMDsalFSLEVRGFKDELRDMI----SGVIQLKEWTIDNNVAVDQKGFEVEASLDFP-G 576
Cdd:cd01347   427 -NPNLKPEKSKQYELGLKYDPGDG---LTLSAALFRIDIKNEIvstpTNTGLGLVTVYVNGGKARIRGVELEASYDLTdG 502

                         570
                  ....*....|.
gi 2443491674 577 TTLRASYGYLD 587
Cdd:cd01347   503 LGLTGSYTYTD 513
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 29-585 9.19e-26

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 112.89  E-value: 9.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTR----VPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNfVGSHTPVTTY--HGtvhYEQRRMQVLVD 102
Cdd:TIGR01786   4 TVTATRTADPQRRdlsvTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVV-EGGRGGSQGIniRG---LDKNRVAVLVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 103 G------RTAHRATLSDMDWetmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPAD------TGGAEFKVTRGS 170
Cdd:TIGR01786  80 GirqntsYGGQGSTFYAINS----IDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADllkpgkDLGGLSKLGYSS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 171 RGHLRTFG-SVGHTGSDYDWRLTYEKR------KFDGFDYQIEGDEQVPFYDGHDINSFTYDSRLQINSQADLEFRGGVV 243
Cdd:TIGR01786 156 ANNRFTQSvAAAGRNDDVDALVQATYRrghelkNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSLEYT 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 244 DGTNYQDRFKSGDLEPLENPDI-----------EVRDFYLQTRFNYATSDRHFfhiqAAVENFDRRQAYAVSFPDNTAQC 312
Cdd:TIGR01786 236 QTDYDEPEMTNTSYLTKPLGAPllsstvvlgdsKTRDRRTGLDYELNPDNSWL----DTVKLALDKQYIQLYNYLNATSA 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 313 lrdgtplYQYTYFDNGDDRERLcftssggemafttvnanSEDTRLEFELQDTLLFS-DNLKLVSGAGFRKD--------- 382
Cdd:TIGR01786 312 -------SDYPGVDKNGRYKDK-----------------YDYYTLGFDTNNKIEFSvHSLSLTYGLDRFKDkvstgdsrr 367

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 383 -----TYRSETYFNGRGNSYQSRY--FGNLEYTPISFMTLNAGGNWEHTST-------TDEGY-------FSPRVAANFT 441
Cdd:TIGR01786 368 nlptaAYNLYGYEGENRPVKGSNFglFLQDNIKLGDWLSLSAGLRYDHYKTdpkadesKDYGAisktysrWSPSLGLTYK 447

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 442 LSNRHALRLVYSEAVRTPDEFEQnpdwgYTlsnvrpaiysdlegfrvdTYAAAEDLDVLTLGK-DLQEERITSREISY-- 518
Cdd:TIGR01786 448 PTPWLTLYYSYSQGFRAPSFDEL-----YG------------------TGAHPGGGPYTFLPNpNLKPETSKNWEIGInl 504

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 519 -FGQFPMDSALFSLEVRGFKDE--LRDMISGVIQLKEWTIDNNVAVDQ---KGFEVEASLDF-------PGTTLRASYGY 585
Cdd:TIGR01786 505 hFDQLDFKVSYFRNDYKDFIDLgiGVTAKGNMAQVGSNTITNYVNIDNariRGIELSGRYDLgsffsgpDGWTTTLKYGY 584
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 38-144 1.96e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 72.69  E-value: 1.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  38 PKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGM-VVNFVGSHTPVTTYHGTvhyEQRRMQVLVDGRTAHRATLSDMDW 116
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVsVSSGGGGGGSSISIRGF---GSNRVLVLVDGVPLNSGGGGSVDL 77

                          90       100
                  ....*....|....*....|....*...
gi 2443491674 117 ETmpVPLEMIERIEVARGPNSAAYGINA 144
Cdd:pfam07715  78 NS--IDPEDIERVEVLKGPASALYGSGA 103
PRK13483 PRK13483
ligand-gated channel protein;
29-469 1.48e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 70.96  E-value: 1.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTYHGTVHYeqrrMQVLVDG-RTAH 107
Cdd:PRK13483   37 VVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVVTGGGDRTDISLRGMGSQY----TLILVDGkRQSS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 108 RATLSDMD-------WetMPvPLEMIERIEVARGPNSAAYGINAFLGTINIITWdpadtggaefKVTRGSRGHLRTFGSV 180
Cdd:PRK13483  113 RETRPNSDgpgveqaW--TP-PLAAIERIEVIRGPMSSLYGSDAIGGVINIITR----------KVPNEWQGEVRLDTTL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 181 ---GHTGSDYDWRL-----------------TYEKRKFDGFDYQiegdeqvpfYDGHDINSFTYDSRLQINSQADLEFRG 240
Cdd:PRK13483  180 qenSDSGNVYQANFfvngplikdllglqlygQYTQREEDDIEGG---------YRDKDARSLTAKLALTPNEDHDIMLEV 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 241 gvvdGTNYQDRFKS--GDLEPLENPDIEVRdfylqtRFNYATSDRHFfhiqaavenfdRRQAYAVSfpdNTAQCLRDGTP 318
Cdd:PRK13483  251 ----GTSNQERDSTvgKTVAPLAPGESCGR------RGCPESSTTEY-----------ERSTVSLS---HTGRWDFGTSD 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 319 LY-QYTYFDNgddRERlcftssggEMAFTTVNANSedtrlefELQDTLLFSDNLKLvsGAGFRKDTYRSET--YFNGRG- 394
Cdd:PRK13483  307 TYiQHEEFDN---KSR--------EMKIKNTDFQS-------SLVAPLGQEHTLTF--GAAYNHQDLTDETsnQISDLTd 366

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2443491674 395 -NSYQSRYFGNLEYTPISFMTLNAGGNWEHtsttDE---GYFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWG 469
Cdd:PRK13483  367 iSRTQWAVFSEDEWRIADDFALTGGLRLDH----DEnfgGHVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTTPDWG 441
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 29-587 5.97e-62

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 218.19  E-value: 5.97e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVT--TYHGtvhYEQRRMQVLVDGRTA 106
Cdd:COG4771    31 VVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRGGSSgiSIRG---LGGDRVLVLIDGVPV 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLSDMdWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVGHTGS- 185
Cdd:COG4771   108 NNPALGGG-GDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTYSGSLSLGGPg 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 186 -DYDWRLTYEKRKFDGFDYQIEGDEQVPfyDGHDINSFTYDSRLQINSQADLEFRGGVVDGTNYQDRFKSGDLEPLENPD 264
Cdd:COG4771   187 dKLSFLLSGSYRDRDGYLDYRNGGFVGN--SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNA 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 265 ieVRDFYLQTRFNYATSDRHFFhiqaavenfdrrqayavsfpdntaqclrdGTPLYQYTYFDNGDDRerlcfTSSGGEMA 344
Cdd:COG4771   265 --GDRDTTTDRGNYSLRYNGDL-----------------------------GDNLDLSLYYSRTDRD-----STNGSLGG 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 345 FTTVNANSEDTRLEFELQDTLLFSDNLKLVSGAGFRKDTYRSETYFNGRGNSYQS-RYFGNLEYTPISFMTLNAGGNWEH 423
Cdd:COG4771   309 STGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDLDSSSFLGGADASRDTyGLFAQDEWKLTDKLTLTAGLRYDY 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 424 TSTTDEG---YFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPAiysdlegfrvdtyaaaedldvl 500
Cdd:COG4771   389 YSTFGASnytAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYVLG---------------------- 446

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 501 tlGKDLQEERITSREISYFGQFPMDSalFSLEVRGFKDELRDMISGVIQLKE----WTIDNNVAVDQKGFEVEASLDF-P 575
Cdd:COG4771   447 --NPDLKPETSDNYELGLEYRLGNGG--LSLSLTGFYTDIKDLIVLVPVGPGpgdvLQYENVGKARTYGLELELKYRLgK 522

                         570
                  ....*....|..
gi 2443491674 576 GTTLRASYGYLD 587
Cdd:COG4771   523 GLTLTASYTYLD 534
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
29-587 4.62e-45

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 171.16  E-value: 4.62e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTYHGtVHYEQRRMQVLVDGRTAHR 108
Cdd:COG1629     5 VVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRG-FGGGGNRVLVLVDGVPLND 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 109 ATLSDMDWETmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVGHTGSDYD 188
Cdd:COG1629    84 PSGGDGGLSY--IDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLSLSGGNGKLA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 189 WRLTYEKRKFDGfdyqiegdeqvpFYDGHDINSFTYDSRL--QINSQADLEFRGGVVDGTNYQDRFKSGDLEPLENPDIE 266
Cdd:COG1629   162 YRLSASYRDSDG------------YRDNSDSDRYNLRAKLgyQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDD 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 267 VRDFYlqtRFNYATSDRHFFHIQAAVENFDRRQAYAVSFpdntaqclrdgtplyQYTYFDNGDDRERLCFTSSGGEmaFT 346
Cdd:COG1629   230 GTNPY---SNDTDDNTRDRYSLSLEYEHLGDGLKLSASA---------------YYRYDDTDLDSDFTPTPADGGT--LE 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 347 TVNANSEDTRLEFELQDTLLFSDNLKLVSGAGFRKDTYRSETYFNGRGNSYQSRY---------------FGNLEYTPIS 411
Cdd:COG1629   290 QTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLtsgadddgtttslalYAQDTYKLTD 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 412 FMTLNAGGNWEHTSTTDEGY---------------FSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVR 476
Cdd:COG1629   370 KLTLTAGLRYDYVSYDVDDTvtgtdsasgsrsysaFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGN 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 477 PaiysdlegfrvdtyaaaedldvltlgkDLQEERITSREISYFGQFPMDSALFSLEV--RGFKDELRDMISGVIQLKEWT 554
Cdd:COG1629   450 P---------------------------DLKPETSTNYELGLRYRLLDGRLSLSLALfySDVDNEILSVPLPNDSGFSTY 502

                         570       580       590
                  ....*....|....*....|....*....|....
gi 2443491674 555 IDNNVAVDQKGFEVEASLDF-PGTTLRASYGYLD 587
Cdd:COG1629   503 YTNAGKARSYGVELELSYQLtPGLSLNASYSYTD 536
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
29-247 1.89e-35

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 135.38  E-value: 1.89e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGS--HTPVTTYHGTvhyEQRRMQVLVDGRTA 106
Cdd:COG4206     2 VVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGpgSAASISIRGL---GSNQTLVLIDGVPL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLSDMDWETmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVGHTGSD 186
Cdd:COG4206    79 NDPSLGGVDLSL--IPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTRRLSASLSGGAGK 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2443491674 187 YDWRLTYEKRKFDGFDYQiegDEQVPFYDGHDINSFTYDSRLQINSQADLEFRGGVVDGTN 247
Cdd:COG4206   157 FSYSLSASYRRSDGYRYN---DPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSER 214
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 45-587 2.79e-26

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 114.47  E-value: 2.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  45 STTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTY-HGTVHYEQRrmqVLVDGRTAHRATLSDMdWETMPVPL 123
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISiRGFGPDRTL---VLVDGLPLASSNYGRG-VDLNTIPP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 124 EMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGS-------RGHLRTFGSVGHTGSdYDWRLTYEKR 196
Cdd:cd01347    77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdnsgssgGGGFDVSGALADDGA-FGARLYGAYR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 197 KFDGFDYQIEGDEQVpFYDGHDIN-SFTYdsrlQINSQADLEFRGGVVDGTNYQD-RFKSGDLEPLENPDIEVRDFYLQT 274
Cdd:cd01347   156 DGDGTIDGDGQADDS-DEERYNVAgKLDW----RPDDDTRLTLDAGYQDQDADGPgGTLPANGTGSSLGGGPSSNTNGDR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 275 RFNYATSDRHFFHIQAAVENFDRRQAYAVSFPDNTAQclRDGTPLYQYTYFDNGDDRERLCFTSSGGEmafttVNANSED 354
Cdd:cd01347   231 DWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTD--NDGDPLILNGGNNAAGGDLGRSGYSSERD-----TTQLGFD 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 355 TRLEFELQDtllFSDNLKLVSGAGFRKDTYrsetyfngrgNSYQSRYFGNLEYTPISFMTLNAGGNWEHTSTTDEGY--- 431
Cdd:cd01347   304 AGLNAPFGT---GPVAHTLTLGVEYRREEL----------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTiag 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 432 ----------FSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPaiysdlegfrvdtyaaaedldvlt 501
Cdd:cd01347   371 gttakksyshWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVG------------------------ 426

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 502 lGKDLQEERITSREISYFGQFPMDsalFSLEVRGFKDELRDMI----SGVIQLKEWTIDNNVAVDQKGFEVEASLDFP-G 576
Cdd:cd01347   427 -NPNLKPEKSKQYELGLKYDPGDG---LTLSAALFRIDIKNEIvstpTNTGLGLVTVYVNGGKARIRGVELEASYDLTdG 502

                         570
                  ....*....|.
gi 2443491674 577 TTLRASYGYLD 587
Cdd:cd01347   503 LGLTGSYTYTD 513
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 29-585 9.19e-26

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 112.89  E-value: 9.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTR----VPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNfVGSHTPVTTY--HGtvhYEQRRMQVLVD 102
Cdd:TIGR01786   4 TVTATRTADPQRRdlsvTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVV-EGGRGGSQGIniRG---LDKNRVAVLVD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 103 G------RTAHRATLSDMDWetmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPAD------TGGAEFKVTRGS 170
Cdd:TIGR01786  80 GirqntsYGGQGSTFYAINS----IDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADllkpgkDLGGLSKLGYSS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 171 RGHLRTFG-SVGHTGSDYDWRLTYEKR------KFDGFDYQIEGDEQVPFYDGHDINSFTYDSRLQINSQADLEFRGGVV 243
Cdd:TIGR01786 156 ANNRFTQSvAAAGRNDDVDALVQATYRrghelkNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSLEYT 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 244 DGTNYQDRFKSGDLEPLENPDI-----------EVRDFYLQTRFNYATSDRHFfhiqAAVENFDRRQAYAVSFPDNTAQC 312
Cdd:TIGR01786 236 QTDYDEPEMTNTSYLTKPLGAPllsstvvlgdsKTRDRRTGLDYELNPDNSWL----DTVKLALDKQYIQLYNYLNATSA 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 313 lrdgtplYQYTYFDNGDDRERLcftssggemafttvnanSEDTRLEFELQDTLLFS-DNLKLVSGAGFRKD--------- 382
Cdd:TIGR01786 312 -------SDYPGVDKNGRYKDK-----------------YDYYTLGFDTNNKIEFSvHSLSLTYGLDRFKDkvstgdsrr 367

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 383 -----TYRSETYFNGRGNSYQSRY--FGNLEYTPISFMTLNAGGNWEHTST-------TDEGY-------FSPRVAANFT 441
Cdd:TIGR01786 368 nlptaAYNLYGYEGENRPVKGSNFglFLQDNIKLGDWLSLSAGLRYDHYKTdpkadesKDYGAisktysrWSPSLGLTYK 447

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 442 LSNRHALRLVYSEAVRTPDEFEQnpdwgYTlsnvrpaiysdlegfrvdTYAAAEDLDVLTLGK-DLQEERITSREISY-- 518
Cdd:TIGR01786 448 PTPWLTLYYSYSQGFRAPSFDEL-----YG------------------TGAHPGGGPYTFLPNpNLKPETSKNWEIGInl 504

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 519 -FGQFPMDSALFSLEVRGFKDE--LRDMISGVIQLKEWTIDNNVAVDQ---KGFEVEASLDF-------PGTTLRASYGY 585
Cdd:TIGR01786 505 hFDQLDFKVSYFRNDYKDFIDLgiGVTAKGNMAQVGSNTITNYVNIDNariRGIELSGRYDLgsffsgpDGWTTTLKYGY 584
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
23-587 1.53e-24

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 109.25  E-value: 1.53e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  23 NEDIPEVLTTTRLRQPKT--RVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVV--NFVGSHTPVTTYHGTVHYEQRRMQ 98
Cdd:COG4772    20 ATTLETVVVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLRRVPGVNVqeEDGFGLRPNIGIRGLGPRRSRGIT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  99 VLVDGRTAHRATLSDMDWETMPvPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFG 178
Cdd:COG4772   100 LLEDGIPIAPAPYGDPAAYYFP-DLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPTAFGGELRVTGGSFGYRRTHA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 179 SVGHTGSDYDWRLTYEKRKFDGF-DYQiegdeqvpfydGHDINSFTYDSRLQINSQADLEFRGGVVDGTNYQ-------- 249
Cdd:COG4772   179 SVGGTVGNFGYLVEYSRKRGDGFrDNS-----------GFDINDFNAKLGYRLSDRQELTLKFQYYDEDANTpggltdaq 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 250 ---DRFKSgdlePLENPDIEVRDFYLQTRFNYATSDRHFFHIQAAVENFDRRQAYAVSFPDNTAQCLRDGTPLYQYTYFd 326
Cdd:COG4772   248 fdaDPRQS----YRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRNWYIRQNTADPNTPGLGLRGNPRGYRSY- 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 327 nGDDrERLCFTSSGGEMAFT-TVNAnsedtRLEFELQDTLLFSDNLKL-VSGAGFRKDTYRSETYFNGRGnSYQSRYFGN 404
Cdd:COG4772   323 -GIE-PRLTHRFELGGVPHTlEVGL-----RYHREEEDRKQYVNTYGQgRSGAGLRRDRRFSADALAAYA-QNRFELTGR 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 405 LeytpisfmTLNAGGNWEHTSTTDEGYFSPRVAANFTLSNRH-----ALRLVYseavrtpdefEQNPDWGytlsnvrpaI 479
Cdd:COG4772   395 L--------TLTPGLRYEHIRRDRTDRYSTRTGGDDSGSNSYseflpGLGLLY----------QLTDNLQ---------L 447

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 480 YSDL-EGFRVDTYaaAEDLDVLTLGKDLQEERITSREI----SYFGQFPMDSALFSLEvrgFKDELRDMISGVIQLKEWT 554
Cdd:COG4772   448 YANVsRGFEPPTF--GDLAYGNGGNPDLKPEKSWNYELgtrgRIGNGLSAEVALFYID---YDNELGSCSAAGGDRSTFT 522

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 2443491674 555 idnNV-AVDQKGFEVEASLDF-----PGTTLRASYGYLD 587
Cdd:COG4772   523 ---NAgETRHQGLELALDYDLlkgggLGLPLFAAYTYTD 558
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 31-455 1.70e-17

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 86.87  E-value: 1.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  31 TTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNfvgshtpvttYHGTVHYEQRRM------QVLVDGr 104
Cdd:COG4773    54 TATKLDTPLRETPQSVSVVTRQLIEDQGATTLDDALRNVPGVTVS----------SYDGGGRDSFSIrgfsidNYLRDG- 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 105 tahratLSDMDWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTF----GSV 180
Cdd:COG4773   123 ------LPLGGFGGGQPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRATadvgGPL 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 181 GHTGSdYDWRLTyekrkfdgFDYQiEGDEQVPFYDGHDIN---SFTYDsrlqINSQADLEFrggvvdGTNYQDRFKSGD- 256
Cdd:COG4773   197 NEDGT-LRYRLN--------AAYE-DGDSFRDGVDNRRTLiapSLDWD----LTDDTTLTL------GAEYQDDDSTGDr 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 257 -LEPLENPDIEV-RDFYLQTRFNYATSDRHFF------------HIQAAV----ENFDRRQAYAVSFPDNTAQCLRDGTP 318
Cdd:COG4773   257 gFLPLDGTLLDLpRSTNLGEPWDYYDTETTTLfaelehrfnddwSLRANArysdSDRDGRSAYAYGAPDAATGTLTRYAS 336

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 319 LYQYTY------------FDNGD---------DRERLCFTSSGG----------------EMAFTTVNANSEDTRLEFEL 361
Cdd:COG4773   337 ARDGDSrsdsldanlngkFETGGlehtllvgaDYSRYDSDSDSAtagtiniynpvygnlpEPDFDASDTDTTTRQTGLYA 416

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 362 QDTLLFSDNLKLVsgAGFRKDTYRSETYFNGRGNsyqsryfgnleytpisfmtlnaggnwehTSTTDEGYFSPRVAANFT 441
Cdd:COG4773   417 QDQISLTDRLSLL--LGGRYDWYETDSTNRLGGS----------------------------TTSYDDSAFTPRAGLVYD 466

                         490
                  ....*....|....
gi 2443491674 442 LSNRHALRLVYSEA 455
Cdd:COG4773   467 LTPGLSLYASYSES 480
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 38-144 1.96e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 72.69  E-value: 1.96e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  38 PKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGM-VVNFVGSHTPVTTYHGTvhyEQRRMQVLVDGRTAHRATLSDMDW 116
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVsVSSGGGGGGSSISIRGF---GSNRVLVLVDGVPLNSGGGGSVDL 77

                          90       100
                  ....*....|....*....|....*...
gi 2443491674 117 ETmpVPLEMIERIEVARGPNSAAYGINA 144
Cdd:pfam07715  78 NS--IDPEDIERVEVLKGPASALYGSGA 103
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
30-455 4.00e-15

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 79.15  E-value: 4.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  30 LTTTRLRQpktrVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGmvvnfvgshtpVTTYHGTVHYEQR--------RMQVLV 101
Cdd:COG4774     1 KTDTPLLD----TPQSVTVVTRELIEDQGATSLADALRNVPG-----------VTFGAGEGGNGDSfsirgfsaSGDIYV 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 102 DGrtahratLSDMDweTMPVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLR-TFGSV 180
Cdd:COG4774    66 DG-------LRDPG--QYRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGSDGQRRaTLDVN 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 181 GHTGSDYDWRLTYEKRKFDGFDYQIEGDEQVpfydghdIN-SFTY--DSRLQINSQADLEFRGGVVD-GTNYQDRFKSGD 256
Cdd:COG4774   137 GPLGDDLAYRLNGMYRDSDSYRDGVDNDRWG-------IApSLTWrlGDRTRLTLDYEYQDDDRTPDyGVPAVANGRPVD 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 257 LEP-----LENPDIEVRDFYLQTRFNYATSDRHFFHIQAAVENFDRRQAYAVSFPDNTAQCLRDGTPLYQYT-------- 323
Cdd:COG4774   210 VDRstfygQPDDYSDSETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRNTYPTGGNATGTVTRSAYRRDQDndtlsnqt 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 324 --------------------YFDNGDDRERLCFTSSGG---------EMAFTTVNANSEDTRLEFE-----LQDTLLFSD 369
Cdd:COG4774   290 dltgkfdtggvkhtllagveYSREDSDNARYSGGGTAPtvnlynpvyGAPVTGPTLGGADNDSRTDttglyLQDTISLTD 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 370 NLKLVsgAGFRKDTYRSETYFNGRGNSyqsryfgnleytpisfmtlnaggnwehTSTTDEGYFSPRVAANFTLSNRHALR 449
Cdd:COG4774   370 RWSLL--AGLRYDRFDTDYTDRTTGAT---------------------------TSSYDDSAFSPRAGLVYKPTPNLSLY 420


                  ....*.
gi 2443491674 450 LVYSEA 455
Cdd:COG4774   421 ASYSTS 426
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 42-256 8.72e-14

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 74.76  E-value: 8.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  42 VPGSTTVIDGDLIRNLGIVNLYEVFRLVPGmvVNFVGSHTpvTTYHGtvHYEQRRMQVLVDGRTAHRATLS-DMDWETMP 120
Cdd:TIGR01783   2 IPQSVSVITRQELEDQQAGSLSEALQRVPG--VVVGGSGG--TTQFG--NITIRGFGLEVDIDNVYLDGVPlLSRGNLAI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 121 VPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLRTFGSVG-HTGSDYDW--RLTYEKRK 197
Cdd:TIGR01783  76 VDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGgPLGADGTFrgRLNGARQD 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2443491674 198 FDGFDyqiegDEQvpfydGHDINSFTYDSRLQINSQADLEFrggvvdGTNYQDRFKSGD 256
Cdd:TIGR01783 156 GDSFY-----DGA-----GEETRLGATATDWQLDDRTLLRL------GAYYQKERDRGG 198
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
 29-286 9.62e-13

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 71.43  E-value: 9.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTY--HGTvhyEQRRMQVLVDGRTA 106
Cdd:TIGR01779  32 VVTANRFAQTASQTLAPVTIITRQDIERTQAKSLPELLRRLPGVSIAQNGGRGQNTSLflRGT---ESDHVLVLIDGIRF 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLSDMDWETMPVplEMIERIEVARGPNSAAYGINAFLGTINIITWDPADTGGAEFKVTRGSRGHLR-TFGSVGHTGS 185
Cdd:TIGR01779 109 GSAAAGAADFQQLPV--ELVERIEYVRGPRSSLYGSEAIGGVINIITRRRSGGQGTTLSAGLGSLDYQEySIASGVAIGE 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 186 DYDWRLTYEKRKFDGFDYQIEGDEQvpfYDGhDINSFTYDSRL-----QINSQADLEFRGGVVDGTNYQDRFKSGdlepl 260
Cdd:TIGR01779 187 NGWYSVALGTESTKGINVRPGGPGV---YDP-DRDGFRSDSLLlggghRFDESWSLFVNALRYENRNDYDNYSFG----- 257

                         250       260
                  ....*....|....*....|....*.
gi 2443491674 261 eNPDIEVRDFYLQTrfnyATSDRHFF 286
Cdd:TIGR01779 258 -TRLYKEAEKGDQS----FTGGRQRQ 278
PRK13483 PRK13483
ligand-gated channel protein;
29-469 1.48e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 70.96  E-value: 1.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTYHGTVHYeqrrMQVLVDG-RTAH 107
Cdd:PRK13483   37 VVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVVTGGGDRTDISLRGMGSQY----TLILVDGkRQSS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 108 RATLSDMD-------WetMPvPLEMIERIEVARGPNSAAYGINAFLGTINIITWdpadtggaefKVTRGSRGHLRTFGSV 180
Cdd:PRK13483  113 RETRPNSDgpgveqaW--TP-PLAAIERIEVIRGPMSSLYGSDAIGGVINIITR----------KVPNEWQGEVRLDTTL 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 181 ---GHTGSDYDWRL-----------------TYEKRKFDGFDYQiegdeqvpfYDGHDINSFTYDSRLQINSQADLEFRG 240
Cdd:PRK13483  180 qenSDSGNVYQANFfvngplikdllglqlygQYTQREEDDIEGG---------YRDKDARSLTAKLALTPNEDHDIMLEV 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 241 gvvdGTNYQDRFKS--GDLEPLENPDIEVRdfylqtRFNYATSDRHFfhiqaavenfdRRQAYAVSfpdNTAQCLRDGTP 318
Cdd:PRK13483  251 ----GTSNQERDSTvgKTVAPLAPGESCGR------RGCPESSTTEY-----------ERSTVSLS---HTGRWDFGTSD 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 319 LY-QYTYFDNgddRERlcftssggEMAFTTVNANSedtrlefELQDTLLFSDNLKLvsGAGFRKDTYRSET--YFNGRG- 394
Cdd:PRK13483  307 TYiQHEEFDN---KSR--------EMKIKNTDFQS-------SLVAPLGQEHTLTF--GAAYNHQDLTDETsnQISDLTd 366

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2443491674 395 -NSYQSRYFGNLEYTPISFMTLNAGGNWEHtsttDE---GYFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWG 469
Cdd:PRK13483  367 iSRTQWAVFSEDEWRIADDFALTGGLRLDH----DEnfgGHVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTTPDWG 441
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 27-153 2.57e-11

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 66.83  E-value: 2.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  27 PEVLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTYHGtvhYEQRRMQVLVDGR-- 104
Cdd:PRK10064   32 TMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRG---LDSSYTLILIDGKrv 108

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2443491674 105 TAHRATLSDMDWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIIT 153
Cdd:PRK10064  109 NSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIIT 157
PRK13513 PRK13513
ligand-gated channel protein;
29-153 4.85e-10

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 62.86  E-value: 4.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFVGSHTPVTTYHGTVHYeqrrMQVLVDG-RTAH 107
Cdd:PRK13513   39 VVTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVPGVVVTGGGSTSDISIRGMAAKY----TLILVDGkRVDT 114

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2443491674 108 RATLSDMD-------WetMPvPLEMIERIEVARGPNSAAYGINAFLGTINIIT 153
Cdd:PRK13513  115 RSTRPNSDgsgieqgW--LP-PLAAIERIEVVRGPMSSLYGSDAMGGVINIIT 164
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
29-173 9.23e-10

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 61.93  E-value: 9.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGM-VVNFVGSHTPVTTY-HGTvhyEQRRMQVLVDGRTA 106
Cdd:PRK10641   29 VVTANRFQQPVSTVLAPTTVVTRDDIDRWQSKSVNDVLRRLPGVdIAQNGGLGQLSSLFiRGT---NSSHVLVLIDGVRL 105

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 107 HRATLS---DMDwetmPVPLEMIERIEVARGPNSAAYGINAFLGTINIITwdPADTGGAEFKVTRGSRGH 173
Cdd:PRK10641  106 NQAGISgsaDLS----QIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIIT--TRDKPGTTLSAGWGSNGY 169
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
29-587 1.78e-09

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 61.18  E-value: 1.78e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  29 VLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNFvGSHTPVTTYHGtvhYEQRRMQVLVDGRTAH- 107
Cdd:PRK13484   34 VVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITG-GNEKPDISIRG---LSGDYTLILVDGRRQSg 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 108 ---RATLSDMDWETMPVPLEMIERIEVARGPNSAAYGINAFLGTINIIT-------WDPADTGGaefkvtrGSRGHLRTF 177
Cdd:PRK13484  110 resRPNGSGGFEAGFIPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITkpvnnqtWDGVLGLG-------GIIQEHGKF 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 178 GSvghtGSDYDWRLTYEKRKfDGFDYQIEGDEqvpFYDGHDINSFTYDSRLQINSQADLEFRGgvVDGTNYQDRFKSGDL 257
Cdd:PRK13484  183 GN----STTNDFYLSGPLIK-DKLGLQLYGGM---NYRKEDSISQGTPAKDNKNITATLQFTP--TESQKFVFEYGKNNQ 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 258 EPLENPDIEVRDFYLQTRFNYATSDRhffhiqaavENFDRRQAYAVSFpDNTAQCLRDGTPLYQYTYFdngddRERlcft 337
Cdd:PRK13484  253 VHTLTPGESLDAWTMRGNLKQPNSKR---------ETHNSRSHWVAAW-NAQGEILHPEIAVYQEKVI-----REV---- 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 338 SSGGEMAFTTVNANSEDTRLE-----FELQDTLLFSDNLkLVSGAGFRKDTYRSETYFNGRGNSYQS------RYFGNLE 406
Cdd:PRK13484  314 KSGKKDKYNHWDLNYESRKPEitntiIDAKVTAFLPENV-LTIGGQFQHAELRDDSATGKKTTETQSvsikqkAVFIENE 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 407 YTPISFMTLNAG---GNWEHTSTtdegYFSPRVAANFTLSNRHALRLVYSEAVRTPDEFEQNPDWGYTLSNVRPAIYSDl 483
Cdd:PRK13484  393 YAATDSLALTGGlrlDNHEIYGS----YWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPGFGTLTQGGASIMYGN- 467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 484 egfrvdtyaaaedldvltlgKDLQEERITSREI----SYFGQFPMDSALFSLEvrgFKDELRDMISGVIQ----LKEWTI 555
Cdd:PRK13484  468 --------------------RDLKPETSVTEEIgiiySNDSGFSASATLFNTD---FKNKLTSYDIGTKDpvtgLNTFIY 524

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 2443491674 556 DNNVAVDQKGfeVEASLDFP---GTTLRASYGYLD 587
Cdd:PRK13484  525 DNVGEANIRG--VELATQIPvydKWHVSANYTFTD 557
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 103-159 2.41e-09

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 60.54  E-value: 2.41e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2443491674 103 GRTAHRATLSDMDWetmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPADT 159
Cdd:PRK13528  125 SWRGERDTRGDTNW----VPPEMVERIEVIRGPAAARYGSGAAGGVVNIITKRPTND 177
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
43-158 8.52e-09

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 58.89  E-value: 8.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  43 PGsTTVIDGDLIRNLGIVN-LYEVFRLVPGmvVNFVGSHTPvTTYHGTVHYEQRRMQ-----VLVDG-----RTA----- 106
Cdd:PRK13524   53 PG-VSTITAEDIRKRPPANdVSEIIRTMPG--VNLTGNSTS-GQRGNNRQIDIRGMGpentlILIDGkpvssRNSvrygw 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2443491674 107 --HRATLSDMDWetmpVPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPAD 158
Cdd:PRK13524  129 rgERDTRGDTNW----VPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKPTG 178
PRK13486 PRK13486
TonB-dependent receptor;
13-158 1.45e-06

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 51.56  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674  13 GFSnGFYAGFNEDIpEVLTTTRLRQPKTRVPGSTTVIDGDLIRNLGIVNLYEVFRLVPGMVVNfvgSHTPVTtyhGTVHY 92
Cdd:PRK13486   15 GFS-ASSIAAAEDV-MIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVE---SGTGKT---GGLEI 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2443491674  93 EQRRMQ-----VLVDGRTAHRAT------LSDMDWETMPvPLEMIERIEVARGPNSAAYGINAFLGTINIITWDPAD 158
Cdd:PRK13486   87 SIRGMPasytlILIDGVRQGGSSdvtpngFSAMNTGFMP-PLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAD 162
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 244-590 7.51e-06

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 49.00  E-value: 7.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 244 DGTNYQDRFKSGDLEPLENPDIEVRDFYLQTRFNYATSDRHFFHIQAAVENFDRRQAYAVSFPDNTAQCLRDGTPLYQYT 323
Cdd:pfam00593   6 LDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 324 YFDNGDDRERLCFTSSGGEMAFTTVNANSEDTRLEFELQDTLLFSDNLKL-----VSGAGFRKDTYRSETYFNGRGNSYQ 398
Cdd:pfam00593  86 RYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLgvelrTAGLDYRRLDDDAYDPYDPANPSSS 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 399 SRY---------FGNLEYTPISFMTLNAGGNWEHTSTT-------------DEGYFSPRVAANFTLSNRHALRLVYSEAV 456
Cdd:pfam00593 166 SYSdtttdsyglYLQDNIKLTDRLTLTLGLRYDHYSTDgddgngggdnfsrSYSAFSPRLGLVYKPTDNLSLYASYSRGF 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 457 RTPDEFEQNPDWGYTLSNVRPAIYSDLEGFRVDTYaaaedldvlTLGKDLQEERitsreisyfgqfpmdsalFSLEVRGF 536
Cdd:pfam00593 246 RAPSLGELYGSGSGGGGGAVAGGNPDLKPETSDNY---------ELGLKYDDGR------------------LSLSLALF 298

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443491674 537 KDELRDMIS-----GVIQLKEWTIDNNVAVDQKGFEVEASLDFPGTTLRAS-YGYLDQDT 590
Cdd:pfam00593 299 YIDIKNLITsdpdgPGLGGTVYTYTNVGKARIRGVELELSGRLWGLGLSGGgYTYTDADD 358
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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