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Conserved domains on  [gi|2443545494|ref|WP_273180174|]
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MULTISPECIES: ANTAR domain-containing protein [Methylophaga]

Protein Classification

ANTAR domain-containing response regulator( domain architecture ID 11467116)

response regulator with a signal receiver (REC) domain and RNA binding antiterminator (ANTAR) domain involved in transcriptional antitermination, similar to Mycobacterium tuberculosis transcriptional regulatory protein pdtaR that is a member of the two-component regulatory system pdtaR/pdtaS

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 26-208 3.22e-29

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


:

Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 107.35  E-value: 3.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494  26 ILLIMPEGENRKKIEQQIRRIGFPLKTEWPPPED-----FSANYQVVMLGLTPIIENNYDFHWDVS-NPPAALVLVVDYE 99
Cdd:COG3707     6 VLVVDDEPLRRADLREGLREAGYEVVAEAADGEDavelvRELKPDLVIVDIDMPDRDGLEAARQISeERPAPVILLTAYS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494 100 NPLVLQYSLSLNAQAIIGLPFHPLGVLSNLLLSLQEFKQTRSMLKTIRNLESKLNASQHIENAKHFISEKQNISLEEAYK 179
Cdd:COG3707    86 DPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEAYR 165

                         170       180
                  ....*....|....*....|....*....
gi 2443545494 180 LLRKQAMEQRMPVGELAKEIIAKQSFSNE 208
Cdd:COG3707   166 LLRKQAMDRRVKLAEVAEAILAAAELLKG 194
 
Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 26-208 3.22e-29

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 107.35  E-value: 3.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494  26 ILLIMPEGENRKKIEQQIRRIGFPLKTEWPPPED-----FSANYQVVMLGLTPIIENNYDFHWDVS-NPPAALVLVVDYE 99
Cdd:COG3707     6 VLVVDDEPLRRADLREGLREAGYEVVAEAADGEDavelvRELKPDLVIVDIDMPDRDGLEAARQISeERPAPVILLTAYS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494 100 NPLVLQYSLSLNAQAIIGLPFHPLGVLSNLLLSLQEFKQTRSMLKTIRNLESKLNASQHIENAKHFISEKQNISLEEAYK 179
Cdd:COG3707    86 DPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEAYR 165

                         170       180
                  ....*....|....*....|....*....
gi 2443545494 180 LLRKQAMEQRMPVGELAKEIIAKQSFSNE 208
Cdd:COG3707   166 LLRKQAMDRRVKLAEVAEAILAAAELLKG 194
ANTAR smart01012
ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found ...
 146-200 2.91e-10

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; The majority of the domain consists of a coiled-coil.


Pssm-ID: 198080 [Multi-domain]  Cd Length: 55  Bit Score: 54.02  E-value: 2.91e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2443545494  146 IRNLESKLNASQHIENAKHFISEKQNISLEEAYKLLRKQAMEQRMPVGELAKEII 200
Cdd:smart01012   1 LEQLREALESRKVIEQAKGILMERRGLSEEEAFELLRKLAMDRNVKLRDVAEAIV 55
ANTAR pfam03861
ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding ...
 152-196 6.07e-08

ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.


Pssm-ID: 427550 [Multi-domain]  Cd Length: 46  Bit Score: 47.33  E-value: 6.07e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2443545494 152 KLNASQHIENAKHFISEKQNISLEEAYKLLRKQAMEQRMPVGELA 196
Cdd:pfam03861   1 ALESRKVIEQAKGILMERLGLSEDEAFRLLRKLSMDRNVKLREVA 45
 
Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 26-208 3.22e-29

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 107.35  E-value: 3.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494  26 ILLIMPEGENRKKIEQQIRRIGFPLKTEWPPPED-----FSANYQVVMLGLTPIIENNYDFHWDVS-NPPAALVLVVDYE 99
Cdd:COG3707     6 VLVVDDEPLRRADLREGLREAGYEVVAEAADGEDavelvRELKPDLVIVDIDMPDRDGLEAARQISeERPAPVILLTAYS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2443545494 100 NPLVLQYSLSLNAQAIIGLPFHPLGVLSNLLLSLQEFKQTRSMLKTIRNLESKLNASQHIENAKHFISEKQNISLEEAYK 179
Cdd:COG3707    86 DPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEAYR 165

                         170       180
                  ....*....|....*....|....*....
gi 2443545494 180 LLRKQAMEQRMPVGELAKEIIAKQSFSNE 208
Cdd:COG3707   166 LLRKQAMDRRVKLAEVAEAILAAAELLKG 194
ANTAR smart01012
ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found ...
 146-200 2.91e-10

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; The majority of the domain consists of a coiled-coil.


Pssm-ID: 198080 [Multi-domain]  Cd Length: 55  Bit Score: 54.02  E-value: 2.91e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2443545494  146 IRNLESKLNASQHIENAKHFISEKQNISLEEAYKLLRKQAMEQRMPVGELAKEII 200
Cdd:smart01012   1 LEQLREALESRKVIEQAKGILMERRGLSEEEAFELLRKLAMDRNVKLRDVAEAIV 55
ANTAR pfam03861
ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding ...
 152-196 6.07e-08

ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.


Pssm-ID: 427550 [Multi-domain]  Cd Length: 46  Bit Score: 47.33  E-value: 6.07e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2443545494 152 KLNASQHIENAKHFISEKQNISLEEAYKLLRKQAMEQRMPVGELA 196
Cdd:pfam03861   1 ALESRKVIEQAKGILMERLGLSEDEAFRLLRKLSMDRNVKLREVA 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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