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Conserved domains on  [gi|2468537687|ref|WP_276819868|]
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polyprenyl diphosphate synthase [Mailhella massiliensis]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-234 5.92e-124

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 351.28  E-value: 5.92e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:COG0020    12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEK----GLRPEELT 157
Cdd:COG0020    92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDvaagELDPEDID 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2468537687 158 EEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTDEQL 234
Cdd:COG0020   172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-234 5.92e-124

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 351.28  E-value: 5.92e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:COG0020    12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEK----GLRPEELT 157
Cdd:COG0020    92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDvaagELDPEDID 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2468537687 158 EEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTDEQL 234
Cdd:COG0020   172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 8-221 1.29e-114

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 326.64  E-value: 1.29e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   8 HIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELPE 87
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  88 LMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKG----LRPEELTEEAFRT 163
Cdd:cd00475    81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVkageLDPEDITEELISK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2468537687 164 LLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYA 221
Cdd:cd00475   161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 2-230 6.41e-113

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 323.75  E-value: 6.41e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:PRK14830   19 KGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARL----ALEKGLRPEELT 157
Cdd:PRK14830   99 DKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEiakdVLDGKLNPEDIT 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2468537687 158 EEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRT 230
Cdd:PRK14830  179 EELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFGGV 251
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 12-228 3.38e-112

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.47  E-value: 3.38e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  12 IMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSF-LFDLFLQFLRQELPELMK 90
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDAlMELLKEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  91 EDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKG--LRPEELTEEAFRTLLYDP 168
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGkkLDPEDIDEELISSHLYTA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687 169 ALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:pfam01255 161 GLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 7-228 1.04e-82

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 246.16  E-value: 1.04e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   7 EHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELP 86
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  87 ELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKGLR----PEELTEEAFR 162
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSgkllPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2468537687 163 TLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
2-234 5.92e-124

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 351.28  E-value: 5.92e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:COG0020    12 PGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLREYL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEK----GLRPEELT 157
Cdd:COG0020    92 RRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDvaagELDPEDID 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2468537687 158 EEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTDEQL 234
Cdd:COG0020   172 EETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSEQV 248
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 8-221 1.29e-114

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 326.64  E-value: 1.29e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   8 HIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELPE 87
Cdd:cd00475     1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  88 LMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKG----LRPEELTEEAFRT 163
Cdd:cd00475    81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVkageLDPEDITEELISK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2468537687 164 LLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYA 221
Cdd:cd00475   161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 2-230 6.41e-113

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 323.75  E-value: 6.41e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:PRK14830   19 KGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVEFL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARL----ALEKGLRPEELT 157
Cdd:PRK14830   99 DKFVPELIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEiakdVLDGKLNPEDIT 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2468537687 158 EEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRT 230
Cdd:PRK14830  179 EELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFGGV 251
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 12-228 3.38e-112

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.47  E-value: 3.38e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  12 IMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSF-LFDLFLQFLRQELPELMK 90
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDAlMELLKEEYLRRELPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  91 EDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKG--LRPEELTEEAFRTLLYDP 168
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGkkLDPEDIDEELISSHLYTA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687 169 ALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:pfam01255 161 GLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 3-229 5.52e-94

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 275.67  E-value: 5.52e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   3 EKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLR 82
Cdd:PRK14831   18 QRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFERVLR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  83 QELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAAR-LALE--KG-LRPEELTE 158
Cdd:PRK14831   98 RELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARaIAQQvqQGeLDPSEIDE 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2468537687 159 EAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14831  178 NLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 1-235 2.97e-90

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 266.17  E-value: 2.97e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   1 MEEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQF 80
Cdd:PRK14836   10 ANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  81 LRQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEK----GLRPEEL 156
Cdd:PRK14836   90 LDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREvaagKLAPDEI 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2468537687 157 TEEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTDEQLR 235
Cdd:PRK14836  170 DEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQIA 248
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 7-228 1.04e-82

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 246.16  E-value: 1.04e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   7 EHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELP 86
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  87 ELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKGLR----PEELTEEAFR 162
Cdd:TIGR00055  81 ELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSgkllPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2468537687 163 TLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14834 PRK14834
isoprenyl transferase;
6-228 3.66e-80

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 240.43  E-value: 3.66e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   6 PEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQEL 85
Cdd:PRK14834   15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRDL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  86 PELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAA-RLALEKG---LRPEELTEEAF 161
Cdd:PRK14834   95 AELHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVrRLAREVAegrLDPASIDAETI 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2468537687 162 RTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:PRK14834  175 SANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFG 241
PRK14838 PRK14838
isoprenyl transferase;
4-234 4.73e-80

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 240.16  E-value: 4.73e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   4 KLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQ 83
Cdd:PRK14838    9 RIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSIEE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  84 ELpeLMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAAR----LALEKGLRPEELTEE 159
Cdd:PRK14838   89 ET--FMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRqiatLVQNGELNPEEITEE 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2468537687 160 AFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTDEQL 234
Cdd:PRK14838  167 SISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQI 241
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 3-229 4.00e-79

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 237.98  E-value: 4.00e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   3 EKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLR 82
Cdd:PRK14832   16 QKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  83 QELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAAR----LALEKGLRPEELTE 158
Cdd:PRK14832   96 RELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRqvaeLVQQGKLSADAVNE 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2468537687 159 EAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14832  176 QLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
2-228 2.54e-76

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 230.09  E-value: 2.54e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:PRK14833    1 MDNTLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKGLRPE---ELTE 158
Cdd:PRK14833   81 KDERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLLESPPSHIgelESLE 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687 159 EAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:PRK14833  161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
8-228 2.75e-70

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 215.01  E-value: 2.75e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   8 HIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELPE 87
Cdd:PRK14839   12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETER 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  88 LMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARlaleKGLRPEELTEEAFRTLLYD 167
Cdd:PRK14839   92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAA----KALGPEGLSREAFSDLLTG 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2468537687 168 PAlPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:PRK14839  168 DG-GDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 3-230 1.87e-67

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 208.10  E-value: 1.87e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   3 EKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLR 82
Cdd:PRK14829   12 NKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIH 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  83 QELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRA----ARLALEKGLRPEELTE 158
Cdd:PRK14829   92 RRREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAaaaiAREVRDGKISGDRVTE 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468537687 159 EAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRT 230
Cdd:PRK14829  172 KMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 2-228 1.19e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 205.99  E-value: 1.19e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFL 81
Cdd:PRK14842    5 ESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVEFI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  82 RQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAA----------RLALEKGL 151
Cdd:PRK14842   85 ETRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAqevflarkakKVTLEKPL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2468537687 152 RPEElteeaFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:PRK14842  165 KEKE-----FEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 4-228 7.29e-64

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 198.68  E-value: 7.29e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   4 KLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQ 83
Cdd:PRK14841    2 RIPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  84 ELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLAL---EKGlRPEELTEEA 160
Cdd:PRK14841   82 EMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILkdvSQG-KKIELTEET 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2468537687 161 FRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFG 228
Cdd:PRK14841  161 FRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFG 228
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 2-229 1.97e-60

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 190.44  E-value: 1.97e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   2 EEKLPEHIAVIMDGNGRWAR----ERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLF 77
Cdd:PRK14840   15 LQSLPRHVAIIMDGNRRWYRkheqFCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLF 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  78 LQFLRQELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARL----ALEKGLRP 153
Cdd:PRK14840   95 NSQLDSQLPYLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKlhqdLANKKISS 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2468537687 154 EELTEEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14840  175 DDISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQRSRRGGK 250
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 4-229 2.65e-59

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 187.65  E-value: 2.65e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   4 KLPEHIAVIMDGNGRWARERGLPR-SRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLR 82
Cdd:PRK14828   25 QVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLDIIEDVVR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  83 QELPElmkEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLAL----EKGLRPEEL-- 156
Cdd:PRK14828  105 QLAPD---GRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLtehkDKGTSIDELae 181

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2468537687 157 --TEEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14828  182 svTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERRFGK 256
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 3-229 7.10e-58

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 185.16  E-value: 7.10e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   3 EKLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLR 82
Cdd:PRK14827   65 DRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRDVVR 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  83 QELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRA----ARLALEKGLRPEELTE 158
Cdd:PRK14827  145 RRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEAtreiAREAAAGRLNPERITE 224

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2468537687 159 EAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14827  225 STIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
13-231 1.19e-57

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 182.49  E-value: 1.19e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  13 MDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQELPELMKED 92
Cdd:PRK10240    1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  93 IRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEK----GLRPEELTEEAFRTLLYDP 168
Cdd:PRK10240   81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQvqqgNLQPDQIDEEMLNQHICMH 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2468537687 169 ALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGRTD 231
Cdd:PRK10240  161 ELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTE 223
PRK14835 PRK14835
isoprenyl transferase;
4-229 1.81e-55

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 178.50  E-value: 1.81e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   4 KLPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQ 83
Cdd:PRK14835   40 KLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREARR 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  84 --ELPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLAL----EKGLRPEE-- 155
Cdd:PRK14835  120 maVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLleaaATGKSPEEva 199

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2468537687 156 --LTEEAFRTLLYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14835  200 aeLTPEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 5-229 6.97e-54

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 173.09  E-value: 6.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   5 LPEHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLFLQFLRQE 84
Cdd:PRK14837    6 LPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLSSE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  85 LPELMKEDIRLSFIGEAGDLPFAVRRALEYAMKKTAGNRSMVFTLAISYAGREEILRAARLALEKGLRPEELTEEAFRTL 164
Cdd:PRK14837   86 FNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFLSSGLDLETLNENVFSKF 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2468537687 165 LYDPALPDPDLVIRTSGEERLSNFLLFQSAYAELYFSPVLWPDFGPEELKKALKSYAGRVRRFGR 229
Cdd:PRK14837  166 LDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFGR 230
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 7-208 1.40e-18

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 82.74  E-value: 1.40e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687   7 EHIAVIMDGNGRWARERGLPRSRGHLAGVDAVRALVRECRRLGIGYVTVYAFSRENWRRPETEVSFLFDLflqflrqELP 86
Cdd:PTZ00349   21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYL-------NLL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687  87 ELMKEDIRLSFIGE-------AGDLPF---AVRRALEYAMKKTAGNRSMVFTLAISYAGREE------------------ 138
Cdd:PTZ00349   94 ILINEDFFFKFIKDnkikikiIGNLSYindAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEmslckfnpnlyfdtyknl 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468537687 139 ------------------------------------ILRAARLALEKG------------LRPEELTEEAFRTLLYDPAL 170
Cdd:PTZ00349  174 leekkilcgsniltdpikegtfaipddedecdyldhELENERIDLDLKfdgdcicgeksfLNEEQIEIVNYHKKLLTSDL 253

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2468537687 171 PDPDLVIRTSGEERLSNFLLFQ-SAYAELYFSPVLWPDF 208
Cdd:PTZ00349  254 PPPNILIRTSGEKRLSDFMLYQiSEFTEIYFINEYWPIF 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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