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Conserved domains on  [gi|2519732627|ref|WP_285218346|]
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DUF2079 domain-containing protein [Rothia aeria]

Protein Classification

glycosyltransferase family protein( domain architecture ID 229536)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG3463 COG3463
Uncharacterized membrane protein [Function unknown];
50-604 1.20e-71

Uncharacterized membrane protein [Function unknown];


:

Pssm-ID: 442686  Cd Length: 554  Bit Score: 240.47  E-value: 1.20e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627  50 TRLREKQGSLLAGLLAVCIFMLYNYYSSQQLLHWITPSWDLAIFTQMAQAYSRFEMPIVPIKGpdFNLWGDHFHPILMLL 129
Cdd:COG3463     4 LALRKDPPLRLLLALAAIFFLVFFLLSLLRHYLFQSAAYDLGIFDQAFWNTSHGRPPISSLKG--FHLLGDHFSPILLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 130 GPVYAFFPSPMTLLVVQNGMVALSVYLTVRFAQRALGglnGHVVGVLLAAAFGLSYGVQQAVAAQFHEVAFALPFLSLSL 209
Cdd:COG3463    82 APLYALFPSPYTLLVIQAVALALGALPLYRLARRRLG---SPRLALLIAAAYLLYPAVFGANLFDFHPEALAPPFLLGAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 210 GHLvlagtqqnpqRASHITHACWWAAPLAFVKEDMGVTAAMIGAIALIRSGWLREAAntlfphaskdvpafwprlrevfs 289
Cdd:COG3463   159 LAL----------ERRRWRLFALLLVLILLVKEDLGLTVAGLGLWLLLRRRRRRLGL----------------------- 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 290 gwtksrgaaeatLLMVWGLFWSYTSMNLILPIFNVN-HQFDYADKVDLFGA---------LKNPLNALQLLFTPDeKAQS 359
Cdd:COG3463   206 ------------ALIVLSLAWFLLATKVIIPLFSGDeAKRAAVGRYSYLGNsvgeiiwnlLTNPGLLLSELFSLD-KLEY 272

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 360 LWLLLMVGAFLWVVSPLAAV-ALPTIAWRMLSSNSSYWLSTWHYSLVLMPIVFMALLDVLVRVHEHRRrvaasahdkaaa 438
Cdd:COG3463   273 LLLLFLPLAFLPLLSPLSLLaALPLLALNLLSDNPSQWSLTHQYSLPLIPFLFLAAIDGLARLKKWRR------------ 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 439 dqntayqkpeqqntpgsdwakpyrnatqaiilkTPLWLVPLLALVFTVAPILTAQPTQPLAQLTdpvftttdqtstevnk 518
Cdd:COG3463   341 ---------------------------------LARAILLWSLIAFLLAPYGYFLKPLDRAAAA---------------- 371

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 519 RRAVDAVPIGASVATDLSIITELIPGRTVYWIghhgePAPDYVVIDRAGTAWGGKPPTNAAQYAADRYGHPYEVAERVGT 598
Cdd:COG3463   372 REAIALIPPDASVLTTNNLAPHLSHRRNIYLV-----PDEDYVLLDLRSPGWPSSESEEALVDRLLNDGEYGLVAQEDGV 446


                  ....*.
gi 2519732627 599 IDIVRR 604
Cdd:COG3463   447 VLLKRN 452
 
Name Accession Description Interval E-value
COG3463 COG3463
Uncharacterized membrane protein [Function unknown];
50-604 1.20e-71

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 442686  Cd Length: 554  Bit Score: 240.47  E-value: 1.20e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627  50 TRLREKQGSLLAGLLAVCIFMLYNYYSSQQLLHWITPSWDLAIFTQMAQAYSRFEMPIVPIKGpdFNLWGDHFHPILMLL 129
Cdd:COG3463     4 LALRKDPPLRLLLALAAIFFLVFFLLSLLRHYLFQSAAYDLGIFDQAFWNTSHGRPPISSLKG--FHLLGDHFSPILLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 130 GPVYAFFPSPMTLLVVQNGMVALSVYLTVRFAQRALGglnGHVVGVLLAAAFGLSYGVQQAVAAQFHEVAFALPFLSLSL 209
Cdd:COG3463    82 APLYALFPSPYTLLVIQAVALALGALPLYRLARRRLG---SPRLALLIAAAYLLYPAVFGANLFDFHPEALAPPFLLGAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 210 GHLvlagtqqnpqRASHITHACWWAAPLAFVKEDMGVTAAMIGAIALIRSGWLREAAntlfphaskdvpafwprlrevfs 289
Cdd:COG3463   159 LAL----------ERRRWRLFALLLVLILLVKEDLGLTVAGLGLWLLLRRRRRRLGL----------------------- 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 290 gwtksrgaaeatLLMVWGLFWSYTSMNLILPIFNVN-HQFDYADKVDLFGA---------LKNPLNALQLLFTPDeKAQS 359
Cdd:COG3463   206 ------------ALIVLSLAWFLLATKVIIPLFSGDeAKRAAVGRYSYLGNsvgeiiwnlLTNPGLLLSELFSLD-KLEY 272

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 360 LWLLLMVGAFLWVVSPLAAV-ALPTIAWRMLSSNSSYWLSTWHYSLVLMPIVFMALLDVLVRVHEHRRrvaasahdkaaa 438
Cdd:COG3463   273 LLLLFLPLAFLPLLSPLSLLaALPLLALNLLSDNPSQWSLTHQYSLPLIPFLFLAAIDGLARLKKWRR------------ 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 439 dqntayqkpeqqntpgsdwakpyrnatqaiilkTPLWLVPLLALVFTVAPILTAQPTQPLAQLTdpvftttdqtstevnk 518
Cdd:COG3463   341 ---------------------------------LARAILLWSLIAFLLAPYGYFLKPLDRAAAA---------------- 371

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 519 RRAVDAVPIGASVATDLSIITELIPGRTVYWIghhgePAPDYVVIDRAGTAWGGKPPTNAAQYAADRYGHPYEVAERVGT 598
Cdd:COG3463   372 REAIALIPPDASVLTTNNLAPHLSHRRNIYLV-----PDEDYVLLDLRSPGWPSSESEEALVDRLLNDGEYGLVAQEDGV 446


                  ....*.
gi 2519732627 599 IDIVRR 604
Cdd:COG3463   447 VLLKRN 452
DUF2079 pfam09852
Predicted membrane protein (DUF2079); This domain, found in various hypothetical prokaryotic ...
 87-576 1.59e-36

Predicted membrane protein (DUF2079); This domain, found in various hypothetical prokaryotic proteins, has no known function.


Pssm-ID: 430879  Cd Length: 457  Bit Score: 142.12  E-value: 1.59e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627  87 SWDLAIFTQMAQAYSRFEMPIVPIKGPD-FNLWGDHFHPILMLLGPVYAFFPSPMTLLVVQNGMVALSVYLTVRFAQRAL 165
Cdd:pfam09852   9 AYDLGIFDQEIWSTSHGRPFYSSLSGLLsYHLLGQHFAPALYLLAPLYALFPSVLTLLLIQALLLSLGGLPLYRLARQRG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 166 GGlnghvvgVLLAAAFGLSYGVQQAVA----AQFHEVAFALPFLSLSLghlvLAGTQQNPQRAshithACWWAAPLAFVK 241
Cdd:pfam09852  89 LN-------RRLALIIALSYLLSPVVInpnlFDFHPEVLAMPLLLLSL----LLALLRKKWWL-----FILLILLLLLVR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 242 EDMGVTAAMIGAIALIRS-GWLREAANTLFphaskdvpafwprlrevfsgwtksrgaaeatllmvWGLFWSYTSMNLILP 320
Cdd:pfam09852 153 EDLGLVVFGLGFWLILRErKRRKEGLIILL-----------------------------------LGIAWFILVTNVLIP 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 321 -----IFNVNHQFDYADKVD-----LFGALKNPLNALQLLFTPD-EKAQSLWLLLMVGAFLWVVSPLAA-VALPTIAWRM 388
Cdd:pfam09852 198 sfsssKSQRFGVERYSYLGDstleiLWNLILQPFLVLQELLSPFgDKLIYLLLLFLPFGFLPLLSPAWLlPALPLLLLNL 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 389 LSSNSSYWLSTWHYSLVLMPIVFMALLDVLvrvhehrrrvaasahdkaaadqntayqkpeqqNTPGSDWAKPYRNatqaI 468
Cdd:pfam09852 278 LSGYPPQLSLGYQYSLPVIPFLFLAAIDGW--------------------------------AKRSSSISLPKIR----R 321

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 469 ILKTPLWLVPLLALVFTVAPILTAQPTQPlaqLTDPVFTTTDQTSteVNKRRAVDAVPIGASVATDLSIITELIPGRTVY 548
Cdd:pfam09852 322 LWTVALVLSLVLTLFFNPHRSLSFLVPDS---ESPWVYLSTSDQL--QNSRELTSLIPPNASVAATTNLAPHLANRRYVY 396

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 2519732627 549 WIGHHGE--------PAPDYVVIDRAGTAWGGKPPT 576
Cdd:pfam09852 397 PFPENGElypldyqlERVDYILLDPAFPGWASRQDT 432
 
Name Accession Description Interval E-value
COG3463 COG3463
Uncharacterized membrane protein [Function unknown];
50-604 1.20e-71

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 442686  Cd Length: 554  Bit Score: 240.47  E-value: 1.20e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627  50 TRLREKQGSLLAGLLAVCIFMLYNYYSSQQLLHWITPSWDLAIFTQMAQAYSRFEMPIVPIKGpdFNLWGDHFHPILMLL 129
Cdd:COG3463     4 LALRKDPPLRLLLALAAIFFLVFFLLSLLRHYLFQSAAYDLGIFDQAFWNTSHGRPPISSLKG--FHLLGDHFSPILLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 130 GPVYAFFPSPMTLLVVQNGMVALSVYLTVRFAQRALGglnGHVVGVLLAAAFGLSYGVQQAVAAQFHEVAFALPFLSLSL 209
Cdd:COG3463    82 APLYALFPSPYTLLVIQAVALALGALPLYRLARRRLG---SPRLALLIAAAYLLYPAVFGANLFDFHPEALAPPFLLGAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 210 GHLvlagtqqnpqRASHITHACWWAAPLAFVKEDMGVTAAMIGAIALIRSGWLREAAntlfphaskdvpafwprlrevfs 289
Cdd:COG3463   159 LAL----------ERRRWRLFALLLVLILLVKEDLGLTVAGLGLWLLLRRRRRRLGL----------------------- 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 290 gwtksrgaaeatLLMVWGLFWSYTSMNLILPIFNVN-HQFDYADKVDLFGA---------LKNPLNALQLLFTPDeKAQS 359
Cdd:COG3463   206 ------------ALIVLSLAWFLLATKVIIPLFSGDeAKRAAVGRYSYLGNsvgeiiwnlLTNPGLLLSELFSLD-KLEY 272

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 360 LWLLLMVGAFLWVVSPLAAV-ALPTIAWRMLSSNSSYWLSTWHYSLVLMPIVFMALLDVLVRVHEHRRrvaasahdkaaa 438
Cdd:COG3463   273 LLLLFLPLAFLPLLSPLSLLaALPLLALNLLSDNPSQWSLTHQYSLPLIPFLFLAAIDGLARLKKWRR------------ 340

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 439 dqntayqkpeqqntpgsdwakpyrnatqaiilkTPLWLVPLLALVFTVAPILTAQPTQPLAQLTdpvftttdqtstevnk 518
Cdd:COG3463   341 ---------------------------------LARAILLWSLIAFLLAPYGYFLKPLDRAAAA---------------- 371

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 519 RRAVDAVPIGASVATDLSIITELIPGRTVYWIghhgePAPDYVVIDRAGTAWGGKPPTNAAQYAADRYGHPYEVAERVGT 598
Cdd:COG3463   372 REAIALIPPDASVLTTNNLAPHLSHRRNIYLV-----PDEDYVLLDLRSPGWPSSESEEALVDRLLNDGEYGLVAQEDGV 446


                  ....*.
gi 2519732627 599 IDIVRR 604
Cdd:COG3463   447 VLLKRN 452
DUF2079 pfam09852
Predicted membrane protein (DUF2079); This domain, found in various hypothetical prokaryotic ...
 87-576 1.59e-36

Predicted membrane protein (DUF2079); This domain, found in various hypothetical prokaryotic proteins, has no known function.


Pssm-ID: 430879  Cd Length: 457  Bit Score: 142.12  E-value: 1.59e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627  87 SWDLAIFTQMAQAYSRFEMPIVPIKGPD-FNLWGDHFHPILMLLGPVYAFFPSPMTLLVVQNGMVALSVYLTVRFAQRAL 165
Cdd:pfam09852   9 AYDLGIFDQEIWSTSHGRPFYSSLSGLLsYHLLGQHFAPALYLLAPLYALFPSVLTLLLIQALLLSLGGLPLYRLARQRG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 166 GGlnghvvgVLLAAAFGLSYGVQQAVA----AQFHEVAFALPFLSLSLghlvLAGTQQNPQRAshithACWWAAPLAFVK 241
Cdd:pfam09852  89 LN-------RRLALIIALSYLLSPVVInpnlFDFHPEVLAMPLLLLSL----LLALLRKKWWL-----FILLILLLLLVR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 242 EDMGVTAAMIGAIALIRS-GWLREAANTLFphaskdvpafwprlrevfsgwtksrgaaeatllmvWGLFWSYTSMNLILP 320
Cdd:pfam09852 153 EDLGLVVFGLGFWLILRErKRRKEGLIILL-----------------------------------LGIAWFILVTNVLIP 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 321 -----IFNVNHQFDYADKVD-----LFGALKNPLNALQLLFTPD-EKAQSLWLLLMVGAFLWVVSPLAA-VALPTIAWRM 388
Cdd:pfam09852 198 sfsssKSQRFGVERYSYLGDstleiLWNLILQPFLVLQELLSPFgDKLIYLLLLFLPFGFLPLLSPAWLlPALPLLLLNL 277

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 389 LSSNSSYWLSTWHYSLVLMPIVFMALLDVLvrvhehrrrvaasahdkaaadqntayqkpeqqNTPGSDWAKPYRNatqaI 468
Cdd:pfam09852 278 LSGYPPQLSLGYQYSLPVIPFLFLAAIDGW--------------------------------AKRSSSISLPKIR----R 321

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2519732627 469 ILKTPLWLVPLLALVFTVAPILTAQPTQPlaqLTDPVFTTTDQTSteVNKRRAVDAVPIGASVATDLSIITELIPGRTVY 548
Cdd:pfam09852 322 LWTVALVLSLVLTLFFNPHRSLSFLVPDS---ESPWVYLSTSDQL--QNSRELTSLIPPNASVAATTNLAPHLANRRYVY 396

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 2519732627 549 WIGHHGE--------PAPDYVVIDRAGTAWGGKPPT 576
Cdd:pfam09852 397 PFPENGElypldyqlERVDYILLDPAFPGWASRQDT 432
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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