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Conserved domains on  [gi|2528348233|ref|WP_289152328|]
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preprotein translocase subunit SecE [Porticoccus sp. W117]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10012582)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

Gene Ontology:  GO:0065002
PubMed:  15546659

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 31-127 2.37e-29

preprotein translocase subunit SecE; Reviewed


:

Pssm-ID: 235587  Cd Length: 92  Bit Score: 101.82  E-value: 2.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528348233  31 NYYFanmaeSDPGLLYRVLGVLALFAMAAFVAAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALL 110
Cdd:PRK05740    1 NYYL-----REQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALI 75

                          90
                  ....*....|....*..
gi 2528348233 111 LWGLDALFGALAKLVIG 127
Cdd:PRK05740   76 LWGLDSILVWLISFITG 92
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 31-127 2.37e-29

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 101.82  E-value: 2.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528348233  31 NYYFanmaeSDPGLLYRVLGVLALFAMAAFVAAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALL 110
Cdd:PRK05740    1 NYYL-----REQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALI 75

                          90
                  ....*....|....*..
gi 2528348233 111 LWGLDALFGALAKLVIG 127
Cdd:PRK05740   76 LWGLDSILVWLISFITG 92
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 62-127 2.26e-21

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 80.64  E-value: 2.26e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2528348233  62 AAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLVIG 127
Cdd:COG0690     3 KKKTGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 75-126 3.35e-14

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 62.06  E-value: 3.35e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2528348233  75 FRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLVI 126
Cdd:pfam00584   4 FKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 71-125 8.50e-14

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 61.08  E-value: 8.50e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2528348233  71 FVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLV 125
Cdd:TIGR00964   1 IFKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
 
Name Accession Description Interval E-value
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 31-127 2.37e-29

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 101.82  E-value: 2.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528348233  31 NYYFanmaeSDPGLLYRVLGVLALFAMAAFVAAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALL 110
Cdd:PRK05740    1 NYYL-----REQSLPVRALAVVVLIAAAGGVALLTAKGKAFFAFAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALI 75

                          90
                  ....*....|....*..
gi 2528348233 111 LWGLDALFGALAKLVIG 127
Cdd:PRK05740   76 LWGLDSILVWLISFITG 92
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 62-127 2.26e-21

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 80.64  E-value: 2.26e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2528348233  62 AAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLVIG 127
Cdd:COG0690     3 KKKTGKGKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLILG 68
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 62-125 1.34e-14

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 63.40  E-value: 1.34e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2528348233  62 AAKTAKGAGFVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLV 125
Cdd:PRK07597    1 LPKMSKMKKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLISLL 64
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 75-126 3.35e-14

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 62.06  E-value: 3.35e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2528348233  75 FRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLVI 126
Cdd:pfam00584   4 FKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 71-125 8.50e-14

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 61.08  E-value: 8.50e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2528348233  71 FVALFRGARTELRKVVWPTAQERNQTTLMVLAVVIVMALLLWGLDALFGALAKLV 125
Cdd:TIGR00964   1 IFKFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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