|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
31-700 |
6.99e-68 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 235.49 E-value: 6.99e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 31 MQPVEVAAIRAGEK---APFAKTNLARKDIEKNNvGQDLPFLLNQTPSVVINSDAGngvGYTGIRIRG--TDASRINVTL 105
Cdd:COG1629 1 LEEVVVTATRTDESlqdVPGSVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAGG---GAGQISIRGfgGGGNRVLVLV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 106 NGIPYNDAE--SQGTYFVDLPDIASsansIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLK 183
Cdd:COG1629 77 DGVPLNDPSggDGGLSYIDPEDIER----VEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 184 FGSGilGKHFTIDGRLSRISSNGYIDRAASNLKSFYFSTAW-VDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNI 262
Cdd:COG1629 153 LSGG--NGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYqLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 263 SGqeqpgkPYPNETDNYTQTHYQLFYNHQ-FNQYWKANAAVfltkgkgYYEEYraDQSLSNYGLPDYIANGDTTSSTDmv 341
Cdd:COG1629 231 TN------PYSNDTDDNTRDRYSLSLEYEhLGDGLKLSASA-------YYRYD--DTDLDSDFTPTPADGGTLEQTDF-- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 342 rqewlDNNFYGSIFSLQYKKE---KTQFTFGGGWNQYDgkHFGNITHAVVQAAVPQNYKWYGDLPAHKKDLSLYAKFAQQ 418
Cdd:COG1629 294 -----DNRTYGLELRLTYDLGfggKHTLLVGLDYQRQD--LDGSGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYK 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 419 LNEHWQLFADMQVRNVNYTINGFRDN-PTLKVKNNYTFFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP- 495
Cdd:COG1629 367 LTDKLTLTAGLRYDYVSYDVDDTVTGtDSASGSRSYSAFSPSLGLTYQlSPNLSLYASYSRGFRAPTFGELYANGTDPYs 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 496 ------KQEELNDVELGVEKK--NKLFSVGANLYYMQYHNQLVLIGNINDVGSYTR-TNIASSYRAGIELQGTAVISNFL 566
Cdd:COG1629 447 vgnpdlKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYyTNAGKARSYGVELELSYQLTPGL 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 567 NLAANLTISKNKISHFTELIDDYDNggtvtnkynqTNISFSPAVIAGGSINFIPVKHGEISLLSKYVSRQYMDNTSQQSR 646
Cdd:COG1629 527 SLNASYSYTDAKFDDDTDGSADLDG----------NRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGA 596
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2532924251 647 SLnPYYVQDVRLTYtlssiDFLKTTTFILQLNNVFNKKYEANGYTFSYYSGGLT 700
Cdd:COG1629 597 PG-GYTLVDLGAGY-----RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
54-698 |
1.72e-33 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 136.81 E-value: 1.72e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 54 RKDIEKNNVgQDLPFLLNQTPSVVINSDAGNGvgYTGIRIRGTDASRINVTLNGIPYNDAESQGTYFVDLPDIASsANSI 133
Cdd:cd01347 7 AEDIEKQPA-TSLADLLRRIPGVSVTRGGGGG--GSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPEL-IERV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 134 QIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKN-TLKFG-SGILGKHFTIDGRL--------SRIS 203
Cdd:cd01347 83 EVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSgGGGFDvSGALADDGAFGARLygayrdgdGTID 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 204 SNGYIDRAASNLKSFYFSTAW-VDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNISGQEQPGKPYPNETDNYTQT 282
Cdd:cd01347 163 GDGQADDSDEERYNVAGKLDWrPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 283 HYQLFYNHqFNQYWKANAAVfltkgkgYYEEYRADQSLSNYGLPDYIANGDTTSSTDMVRQEWLDNNFYGSI-FSLQYKK 361
Cdd:cd01347 243 SLGLEHDL-NDTGWTLRANL-------SYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLnAPFGTGP 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 362 EKTQFTFGGGWNQYDGkhfgnithavvqaavpqNYKWYGdlpahkkdlsLYAKFAQQLNEHWQLfaDMQVRNVNYTINGF 441
Cdd:cd01347 315 VAHTLTLGVEYRREEL-----------------DEKQTA----------LYAQDTIELTDDLTL--TLGLRYDHYDQDSK 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 442 -RDNPTLKVKNNYTFFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP---------KQEELNDVELGVE-K 509
Cdd:cd01347 366 dTIAGGTTAKKSYSHWSPSLGLVYKlTDGLSLYASYSQGFRAPSLGELYGGGSHGGtaavgnpnlKPEKSKQYELGLKyD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 510 KNKLFSVGANLYYMQYHNQLVLIGNINDVGSYTRTNIASSYRA-GIELQGTAVISNFLNLAANLTISKNKISHFTELIDD 588
Cdd:cd01347 446 PGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIrGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGATTG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 589 YDNGGTVTNKYNqtnisfspaviAGGSINFiPVKHGEISLLSKYVSRQY-MDNTSQQSRSLNPYYVQDVRLTYtlssiDF 667
Cdd:cd01347 526 NRLPGIPKHTAN-----------LGLDYEL-PDEGLTAGGGVRYRGKQYaDTANGNNTVKVPGYTLVDLSASY-----QF 588
|
650 660 670
....*....|....*....|....*....|.
gi 2532924251 668 LKTTTFILQLNNVFNKKYEANGYTFSYYSGG 698
Cdd:cd01347 589 TKNLTLRLGVNNLFDKDYYTSLSVRGSGLYG 619
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
44-705 |
8.84e-24 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 106.73 E-value: 8.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 44 KAPFAKTNLARKDIEKNNVGqDLPFLLNQTPSVVINSDAGNGVgYTGIRIRGTD--ASRINVTLNGIPynDAESQGTYFV 121
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAG-SLSEALQRVPGVVVGGSGGTTQ-FGNITIRGFGleVDIDNVYLDGVP--LLSRGNLAIV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 122 DLPDIassaNSIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTwKNTLKFGSGILGKHFTIDGRLS- 200
Cdd:TIGR01783 77 DPAMV----ERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSG-YRTAFDLGGPLGADGTFRGRLNg 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 201 -RISSNGYIDRAASNLKSFYFSTAW---VDAKNSLRLnifsgkekTYQAW----NGVAEALLKTDRTYNISGQEQPGKPY 272
Cdd:TIGR01783 152 aRQDGDSFYDGAGEETRLGATATDWqldDRTLLRLGA--------YYQKErdrgGYGGLPASGGTSGRDLSSDRYLGTSS 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 273 PNETDNYTQTHYQLFYNHQFNQYWKANAAVFLtkgkgyyeeYRADQSLSNYGLPDYIANGDTTSSTDMV----RQEWLDN 348
Cdd:TIGR01783 224 NRNYDDREYLSYGLSLEYQFNDVWTGKQNLRY---------SYFDTDSNQVQASGYSSDGGLFGRSLTVvnvkQDRVQID 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 349 NFYGSIFSLQYKKEKtqFTFGGGWNQYDGKHFGNithavvQAAVPQN-YKWYGDLPAHKKD---------------LSLY 412
Cdd:TIGR01783 295 AGLDGEFETGPIEHD--LLLGVSYGQRTTNRFNN------TGYPSDNiYSLTATSSARTDIgdspkdralssttkaLNGV 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 413 AKFAQQLNEHWQLFADMQVRNVNYTINGFRDNPTLKVKNNYtfFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGK 491
Cdd:TIGR01783 367 ALQRILLADKWTLTLGGRYDSVDVKSNNGVAGSTGKRDDSQ--FTPSLGVAYKpTDDWSLYASYAESFKPGGYYPKGAGN 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 492 TQQP-KQEELNDVELGVE-KKNKLFSVGANLYYMQYHNQLVlignindVGSYTRTNIASSYRA---GIELQGTAVISNFL 566
Cdd:TIGR01783 445 SGDIlEPEKGKNYELGVRyDLGDSLLATAALFRITKDNQLV-------QDPVNGTFSVNAGKTrnrGVELEARGYLTPGL 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 567 NLAANLTISKNKishFTELIDDYDNGGTVTNKYNQTNISFSPAVIAGGSINFipvkhgEISLLSKYVSRQYMDNTSqqSR 646
Cdd:TIGR01783 518 SLSAGYTYTDAE---FTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGL------TLGGGVQYTGKAYVDGGN--TG 586
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 2532924251 647 SLNPYYVQDVRLTYTLSSidfLKTTTFILQLNNVFNKKyeangYTFSYYSGGLTTENYY 705
Cdd:TIGR01783 587 KVPSYTVVDLSVRYDLTK---KKNLTLALNVNNLFDRD-----YYTSGYRWGPSAYIYP 637
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
223-720 |
1.75e-20 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 95.22 E-value: 1.75e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 223 AWVDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNISGQ-EQPGKPYPNETDNYTQTHYQLFYNHQFNQYWKANAA 301
Cdd:pfam00593 1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYlGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 302 VfltKGKGYYEEYRADQSLSNYGLPDYiangDTTSSTDMVRQEWLDNNFYGSIFSLQYKkektqfTFGGGWNQYDGKHFG 381
Cdd:pfam00593 81 L---RLGLRYSSLDGDYTSNSSGLSGA----GDYLSDDRLYGLYGLDGDLELSLDLSHD------LLLGVELRTAGLDYR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 382 NITHAVVQAAVPQNYKWYGDLPAHKKDLSLYAKFAQQLNEHWQLFADMQVRNVNYTINGFRDNPTlKVKNNYTFFNPKAG 461
Cdd:pfam00593 148 RLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGD-NFSRSYSAFSPRLG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 462 ITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP-----------KQEELNDVELGVEKKNKLFSVGANLYYMQYHNQL 529
Cdd:pfam00593 227 LVYKpTDNLSLYASYSRGFRAPSLGELYGSGSGGGggavaggnpdlKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLI 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 530 VLI--GNINDVGSYTRTNIASSYRAGIELQGTAVISNFLNLAANLTIsknkishfteliddYDNGGTVTNKYNQTNISFS 607
Cdd:pfam00593 307 TSDpdGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLGLSGGGYTY--------------TDADDDADADDTGNPLPNV 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 608 PAVIAGGSINFIPVKHG-EISLLSKYVSRQYM-DNTSQQSRSLNPYYVQDVRLTYTLSsidflKTTTFILQLNNVFNKKY 685
Cdd:pfam00593 373 PRHTANLGLTYDFPLGGwGARLGARYVGSGERrYGDAANTFKTPGYTLVDLSAGYRLN-----KNLTLRLGVNNLFDKYY 447
|
490 500 510
....*....|....*....|....*....|....*
gi 2532924251 686 EangytfsYYSGGLTTENYYFPMAPFNCMLGVNIR 720
Cdd:pfam00593 448 K-------RYYSSGGGNLGGYPGPGRTFYLGLSYK 475
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
31-700 |
6.99e-68 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 235.49 E-value: 6.99e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 31 MQPVEVAAIRAGEK---APFAKTNLARKDIEKNNvGQDLPFLLNQTPSVVINSDAGngvGYTGIRIRG--TDASRINVTL 105
Cdd:COG1629 1 LEEVVVTATRTDESlqdVPGSVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAGG---GAGQISIRGfgGGGNRVLVLV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 106 NGIPYNDAE--SQGTYFVDLPDIASsansIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLK 183
Cdd:COG1629 77 DGVPLNDPSggDGGLSYIDPEDIER----VEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 184 FGSGilGKHFTIDGRLSRISSNGYIDRAASNLKSFYFSTAW-VDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNI 262
Cdd:COG1629 153 LSGG--NGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYqLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 263 SGqeqpgkPYPNETDNYTQTHYQLFYNHQ-FNQYWKANAAVfltkgkgYYEEYraDQSLSNYGLPDYIANGDTTSSTDmv 341
Cdd:COG1629 231 TN------PYSNDTDDNTRDRYSLSLEYEhLGDGLKLSASA-------YYRYD--DTDLDSDFTPTPADGGTLEQTDF-- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 342 rqewlDNNFYGSIFSLQYKKE---KTQFTFGGGWNQYDgkHFGNITHAVVQAAVPQNYKWYGDLPAHKKDLSLYAKFAQQ 418
Cdd:COG1629 294 -----DNRTYGLELRLTYDLGfggKHTLLVGLDYQRQD--LDGSGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYK 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 419 LNEHWQLFADMQVRNVNYTINGFRDN-PTLKVKNNYTFFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP- 495
Cdd:COG1629 367 LTDKLTLTAGLRYDYVSYDVDDTVTGtDSASGSRSYSAFSPSLGLTYQlSPNLSLYASYSRGFRAPTFGELYANGTDPYs 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 496 ------KQEELNDVELGVEKK--NKLFSVGANLYYMQYHNQLVLIGNINDVGSYTR-TNIASSYRAGIELQGTAVISNFL 566
Cdd:COG1629 447 vgnpdlKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYyTNAGKARSYGVELELSYQLTPGL 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 567 NLAANLTISKNKISHFTELIDDYDNggtvtnkynqTNISFSPAVIAGGSINFIPVKHGEISLLSKYVSRQYMDNTSQQSR 646
Cdd:COG1629 527 SLNASYSYTDAKFDDDTDGSADLDG----------NRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGA 596
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2532924251 647 SLnPYYVQDVRLTYtlssiDFLKTTTFILQLNNVFNKKYEANGYTFSYYSGGLT 700
Cdd:COG1629 597 PG-GYTLVDLGAGY-----RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
1-721 |
4.02e-40 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 157.01 E-value: 4.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 1 MKKLLLSGMLCAMGITTIAQETkkfndtsfMQPVEVAAIRAGEKA----PFAKTNLARKDIEK---NNVGQdlpfLLNQT 73
Cdd:COG4772 1 MRRALAAALLLAAAAAAEAATT--------LETVVVTGSRAAEARlkdvPGSVSVVDREELENqaaTSLRE----VLRRV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 74 PSVVINSDAGNGVGyTGIRIRGTDASR---INVTLNGIPYNDA---ESQGTYFvdlPDIASsANSIQIQRGVGTSSNGAG 147
Cdd:COG4772 69 PGVNVQEEDGFGLR-PNIGIRGLGPRRsrgITLLEDGIPIAPApygDPAAYYF---PDLER-MERIEVLRGAAALRYGPQ 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 148 SFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLKFGsGILGKhFTIDGRLSRISSNGYIDRAASNLKSFYFSTAW-VD 226
Cdd:COG4772 144 TVGGAINFVTRTIPTAFGGELRVTGGSFGYRRTHASVG-GTVGN-FGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYrLS 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 227 AKNSLRLNI--FSGKEKTYqawNGVAEALLKTDRTYNisgqeqpgkPYPNETDNYTQTHYQLFYNHQFNQYWKANAAVFl 304
Cdd:COG4772 222 DRQELTLKFqyYDEDANTP---GGLTDAQFDADPRQS---------YRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAY- 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 305 tkgkgYYEEYRADQSLSNYGLPDYIANGDTTSStdmvRQEWldnnFYG--SIFSLQYKKEKTQFTFGGG----WNQYDGK 378
Cdd:COG4772 289 -----YNDFSRNWYIRQNTADPNTPGLGLRGNP----RGYR----SYGiePRLTHRFELGGVPHTLEVGlryhREEEDRK 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 379 HFGNITHAVVQAAVPQNYKWYGdlpahKKDLSLYAKFAQQLNEHWQLFADMQVRNVNYTINGF---RDNPTLKVKNNYTF 455
Cdd:COG4772 356 QYVNTYGQGRSGAGLRRDRRFS-----ADALAAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRystRTGGDDSGSNSYSE 430
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 456 FNPKAGITYN-NNNWQVYASYARaGKEP--NRDDFEAGKTQQPKQEELND-VELGVE-KKNKLFSVGANLYYMQYHNQLV 530
Cdd:COG4772 431 FLPGLGLLYQlTDNLQLYANVSR-GFEPptFGDLAYGNGGNPDLKPEKSWnYELGTRgRIGNGLSAEVALFYIDYDNELG 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 531 LIGNINDVGSyTRTNIASSYRAGIELQGTAVISNF----LNLAANLTISKnkiSHFTELIDDyDNGGtvtnkyNQtnISF 606
Cdd:COG4772 510 SCSAAGGDRS-TFTNAGETRHQGLELALDYDLLKGgglgLPLFAAYTYTD---AEFTSDFGP-VFAG------NR--LPY 576
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 607 SPAVIAGGSINFIPvKHGEISLLSKYVSRQYMDNT----SQQSRSLNPYYVQDVRLTYtlssiDFLKTTTFILQLNNVFN 682
Cdd:COG4772 577 VPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAAntvaDGSFGKIPSYTVLDLSASY-----DFGKNLSLFAGVNNLFD 650
|
730 740 750
....*....|....*....|....*....|....*....
gi 2532924251 683 KKYEANGYTFsyYSGGlttenyYFPMAPFNCMLGVNIRL 721
Cdd:COG4772 651 KRYIASRAPN--YAAG------IRPGPPRTVYAGLRLKF 681
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
31-663 |
6.53e-40 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 155.78 E-value: 6.53e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 31 MQPVEVAAIRAGEK---APFAKTNLARKDIEKNNVgQDLPFLLNQTPSVVINSDAGNGvGYTGIRIRGTDASRINVTLNG 107
Cdd:COG4771 27 LEEVVVTATRTEQSlsdAPASVSVITAEEIEKLGA-TDLADALRLLPGVSVTRSGGRG-GSSGISIRGLGGDRVLVLIDG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 108 IPYNDAESQGTY---FVDLPDIASsansIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLKF 184
Cdd:COG4771 105 VPVNNPALGGGGdlsYIPPDDIER----IEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTYSGSL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 185 GSGILGKHFTIDGRLSRISSNGYIDRAASNL--------KSFYFSTAW-VDAKNSLRLNIFSGKEKTYQAWNGVAEALLK 255
Cdd:COG4771 181 SLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFvgnsgyerYNLNAKLGYrLSDNHRLSLSGGYSRQDRDGGPPTLGDTEIS 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 256 TDRTYnisgqeqpgkpypNETDNYTQTHYQLFYNHQFNQYWKANAavfltkgkgYYEEYRADQslSNYGLPDYIANGDTT 335
Cdd:COG4771 261 SDNAG-------------DRDTTTDRGNYSLRYNGDLGDNLDLSL---------YYSRTDRDS--TNGSLGGSTGSFSDS 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 336 sstdmvrqewlDNNFYGSIFSLQYK-KEKTQFTFGGGWNQYDGkhfgnithavvqaavpQNYKWYGDLPAHKKDLSLYAK 414
Cdd:COG4771 317 -----------DDTTYGLELDLTYPlGGNHTLTLGAEYRYDDL----------------DSSSFLGGADASRDTYGLFAQ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 415 FAQQLNEHWQLFAdmqvrnvnytinGFR-DNPTLKVKNNYTFFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGKT 492
Cdd:COG4771 370 DEWKLTDKLTLTA------------GLRyDYYSTFGASNYTAFSPRLGLRYDlSDNLTLRASYGRGFRAPSLAELYGSGT 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 493 QQP----------KQEELNDVELGVEKK--NKLFSVGANLYYMQYHNQLVLIGNINDVGS-YTRTNIASSYRAGIELQGT 559
Cdd:COG4771 438 GTPgryvlgnpdlKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDvLQYENVGKARTYGLELELK 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 560 AVISNFLNLAANLTISKNKIshfteliddyDNGGTvtnkynQTNISFSPAVIAGGSINFIPVKHGEISLLSKYVSRQYMD 639
Cdd:COG4771 518 YRLGKGLTLTASYTYLDSKI----------DDGDT------GEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVT 581
|
650 660
....*....|....*....|....*
gi 2532924251 640 -NTSQQSRSLNPYYVQDVRLTYTLS 663
Cdd:COG4771 582 pPSGRLEGYTPGYTLLDLRASYKLT 606
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
69-720 |
5.05e-34 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 138.87 E-value: 5.05e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 69 LLNQTPSVVINSdaGNGVGYTGIRIRGTDASriNVTLNGIPyndaesQGTYFVDLPDIASsANSIQIQRGVGTSSNGAGS 148
Cdd:COG4773 88 ALRNVPGVTVSS--YDGGGRDSFSIRGFSID--NYLRDGLP------LGGFGGGQPDTAN-LERVEVLKGPAGLLYGAGS 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 149 FGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLKFGsGILGKHFTIDGRL--SRISSNGYIDRAASNLKSFYFSTAW-V 225
Cdd:COG4773 157 PGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRATADVG-GPLNEDGTLRYRLnaAYEDGDSFRDGVDNRRTLIAPSLDWdL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 226 DAKNSLRLNI--FSGKEKTYQAWNGVAEALLKTDRTYNISGqeqpgkpyPNETDNYTQTHYQLFYNHQFNQYWKANAAVf 303
Cdd:COG4773 236 TDDTTLTLGAeyQDDDSTGDRGFLPLDGTLLDLPRSTNLGE--------PWDYYDTETTTLFAELEHRFNDDWSLRANA- 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 304 ltkgkGYYEEYRADQSLSNYGLPDyIANGDTTSSTDMVRQEW----LDNNFYG--SIFSLQYkkektQFTFGGGWNQYDG 377
Cdd:COG4773 307 -----RYSDSDRDGRSAYAYGAPD-AATGTLTRYASARDGDSrsdsLDANLNGkfETGGLEH-----TLLVGADYSRYDS 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 378 KHFGNITHAV-----VQAAVPQNYKWYGDLPAHKKDLSLYAKfAQ-QLNEHWQLFAdmQVRNVNYTINGFRDNPTLKVKN 451
Cdd:COG4773 376 DSDSATAGTIniynpVYGNLPEPDFDASDTDTTTRQTGLYAQ-DQiSLTDRLSLLL--GGRYDWYETDSTNRLGGSTTSY 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 452 NYTFFNPKAGITYN-NNNWQVYASYARaGKEPNRDDFEAGKTQQPkqEELNDVELGVekKNKLF----SVGANLYYMQYH 526
Cdd:COG4773 453 DDSAFTPRAGLVYDlTPGLSLYASYSE-SFEPQSGADNNGNPLDP--ETGKQYEAGV--KGELFdgrlNATLAVFDITQK 527
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 527 NQLVLIGNINDVgsYTRTNIASSYraGIELQGTAVISNFLNLAANLTISKNKISHFTelidDYDNGGTVTN--------- 597
Cdd:COG4773 528 NVATTDPDNPNF--YVQVGEVRSR--GVELELSGELTPGLNLIAGYTYTDAKITKDA----DALEGKRLTNvprhtaslw 599
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 598 -KYNQTNISFSPAVIaGGSINfipvkhgeisllskYVSRQYMDNTSQQsrSLNPYYVQDVRLTYtlssiDFLKTTTFILQ 676
Cdd:COG4773 600 tTYRFPSGALKGLGL-GGGVR--------------YVGERYGDAANTF--TLPSYTLVDAGARY-----DLGKNWTLQLN 657
|
650 660 670 680
....*....|....*....|....*....|....*....|....
gi 2532924251 677 LNNVFNKKYeangYTFSYYSggltteNYYFPMAPFNCMLGVNIR 720
Cdd:COG4773 658 VNNLFDKKY----YASSGSR------GYVYYGAPRNVRLSLSYK 691
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
54-698 |
1.72e-33 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 136.81 E-value: 1.72e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 54 RKDIEKNNVgQDLPFLLNQTPSVVINSDAGNGvgYTGIRIRGTDASRINVTLNGIPYNDAESQGTYFVDLPDIASsANSI 133
Cdd:cd01347 7 AEDIEKQPA-TSLADLLRRIPGVSVTRGGGGG--GSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPEL-IERV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 134 QIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKN-TLKFG-SGILGKHFTIDGRL--------SRIS 203
Cdd:cd01347 83 EVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSgGGGFDvSGALADDGAFGARLygayrdgdGTID 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 204 SNGYIDRAASNLKSFYFSTAW-VDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNISGQEQPGKPYPNETDNYTQT 282
Cdd:cd01347 163 GDGQADDSDEERYNVAGKLDWrPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 283 HYQLFYNHqFNQYWKANAAVfltkgkgYYEEYRADQSLSNYGLPDYIANGDTTSSTDMVRQEWLDNNFYGSI-FSLQYKK 361
Cdd:cd01347 243 SLGLEHDL-NDTGWTLRANL-------SYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLnAPFGTGP 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 362 EKTQFTFGGGWNQYDGkhfgnithavvqaavpqNYKWYGdlpahkkdlsLYAKFAQQLNEHWQLfaDMQVRNVNYTINGF 441
Cdd:cd01347 315 VAHTLTLGVEYRREEL-----------------DEKQTA----------LYAQDTIELTDDLTL--TLGLRYDHYDQDSK 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 442 -RDNPTLKVKNNYTFFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP---------KQEELNDVELGVE-K 509
Cdd:cd01347 366 dTIAGGTTAKKSYSHWSPSLGLVYKlTDGLSLYASYSQGFRAPSLGELYGGGSHGGtaavgnpnlKPEKSKQYELGLKyD 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 510 KNKLFSVGANLYYMQYHNQLVLIGNINDVGSYTRTNIASSYRA-GIELQGTAVISNFLNLAANLTISKNKISHFTELIDD 588
Cdd:cd01347 446 PGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIrGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGATTG 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 589 YDNGGTVTNKYNqtnisfspaviAGGSINFiPVKHGEISLLSKYVSRQY-MDNTSQQSRSLNPYYVQDVRLTYtlssiDF 667
Cdd:cd01347 526 NRLPGIPKHTAN-----------LGLDYEL-PDEGLTAGGGVRYRGKQYaDTANGNNTVKVPGYTLVDLSASY-----QF 588
|
650 660 670
....*....|....*....|....*....|.
gi 2532924251 668 LKTTTFILQLNNVFNKKYEANGYTFSYYSGG 698
Cdd:cd01347 589 TKNLTLRLGVNNLFDKDYYTSLSVRGSGLYG 619
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
46-720 |
9.49e-29 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 122.29 E-value: 9.49e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 46 PFAKTNLARKDIEKNNVgQDLPFLLNQTPSVVINsdAGNGVGYTGIRIRGTDASrINVTLNGIPYNDAESQGTYFVDlpd 125
Cdd:COG4774 10 PQSVTVVTRELIEDQGA-TSLADALRNVPGVTFG--AGEGGNGDSFSIRGFSAS-GDIYVDGLRDPGQYRRDTFNLE--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 126 iassanSIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLKFGsGILGKHFTIdgRL--SRIS 203
Cdd:COG4774 83 ------RVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGSDGQRRATLDVN-GPLGDDLAY--RLngMYRD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 204 SNGYIDRAASNLKSFYFSTAW-VDAKNSLRLNIFSGKEKT---YQAWNGVAEALLKTDRTYNISgqeqpgkpYPNETDNY 279
Cdd:COG4774 154 SDSYRDGVDNDRWGIAPSLTWrLGDRTRLTLDYEYQDDDRtpdYGVPAVANGRPVDVDRSTFYG--------QPDDYSDS 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 280 TQTHYQLFYNHQFNQYWKANAAVFLTKGKGYYEEYRADQSLSNYGLPDYIANGDTTSSTDMVRQE--------WLDNNFY 351
Cdd:COG4774 226 ETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRNTYPTGGNATGTVTRSAYRRDQDNDTLSNQTDltgkfdtgGVKHTLL 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 352 GSIFSLQYKKEKTQFTFGGGWNQydgkhfGNITHAVVQAAVPQNYKWYGDLPAHKKDLSLYAkFAQ-QLNEHWQLFA--- 427
Cdd:COG4774 306 AGVEYSREDSDNARYSGGGTAPT------VNLYNPVYGAPVTGPTLGGADNDSRTDTTGLYL-QDTiSLTDRWSLLAglr 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 428 --DMQVRNVNYTINGFRDNptlkvkNNYTFFNPKAGITYN-NNNWQVYASYARaGKEPNRDDFEAGKTQQP-KQEELNDV 503
Cdd:COG4774 379 ydRFDTDYTDRTTGATTSS------YDDSAFSPRAGLVYKpTPNLSLYASYST-SFNPGGGAPSLSNAGQAlDPEKSRQY 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 504 ELGVekKNKLF----SVGANLYYMQYHNQLVLigniNDVGSYTRTNIASSYRAGIELQGTAVISNFLNLAANLTisknki 579
Cdd:COG4774 452 EVGV--KWDLLdgrlSLTAALFRIEKTNVRTT----DPANPGVYVQTGEQRSRGVELEATGELTPGWSVLAGYT------ 519
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 580 shfteLID-DYDNGGTVTNKYNQtnISFSPAVIAGGSINF-IPVKHGEISLLSKYVSRQYMDNTSqqSRSLNPYYVQDVR 657
Cdd:COG4774 520 -----YLDaEITKSANAANVGNR--LPNVPRHSASLWTTYdLPLPGLTLGGGVRYVGSRYADAAN--TVKLPSYTRFDAG 590
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2532924251 658 LTYtlssiDFLKTTTFILQLNNVFNKKYeangYTFSYYSggltteNYYFPMAPFNCMLGVNIR 720
Cdd:COG4774 591 ASY-----RLNKNLTLRLNVNNLTDKRY----YASAYGS------GYVTPGAPRTVLLSASYR 638
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
34-323 |
4.24e-24 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 102.64 E-value: 4.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 34 VEVAAIRAGEK---APFAKTNLARKDIEKNNVgQDLPFLLNQTPSVVINSDAGNGvGYTGIRIRGTDASRINVTLNGIPY 110
Cdd:COG4206 1 VVVTATRLEQSksdLTGSVTVIDAEELERSGA-TSLADALRRVPGVQVSSSGGPG-SAASISIRGLGSNQTLVLIDGVPL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 111 NDAESQGTYFVDLPdiASSANSIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTWKNTLKFGSGILG 190
Cdd:COG4206 79 NDPSLGGVDLSLIP--PDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTRRLSASLSGGAGK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 191 KHFTIDGrlSRISSNGYIDRAASnlksfYFSTAWVDAKN-SLRLNIFSGKEKTYQAwngvaeALLKTDRTYNisgqeqpg 269
Cdd:COG4206 157 FSYSLSA--SYRRSDGYRYNDPD-----LRNNDGYENTSlNARLGYKLGDNGSLSL------SGGYSDSERG-------- 215
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2532924251 270 kpYPNETDNYTQTHYQLFYNHQFNQYWKANAAVFLTKGKGYYEEYRADQSLSNY 323
Cdd:COG4206 216 --YPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNT 267
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
44-705 |
8.84e-24 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 106.73 E-value: 8.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 44 KAPFAKTNLARKDIEKNNVGqDLPFLLNQTPSVVINSDAGNGVgYTGIRIRGTD--ASRINVTLNGIPynDAESQGTYFV 121
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAG-SLSEALQRVPGVVVGGSGGTTQ-FGNITIRGFGleVDIDNVYLDGVP--LLSRGNLAIV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 122 DLPDIassaNSIQIQRGVGTSSNGAGSFGGNINLSTNEVNEKFYTELNNSYGSYNTwKNTLKFGSGILGKHFTIDGRLS- 200
Cdd:TIGR01783 77 DPAMV----ERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSG-YRTAFDLGGPLGADGTFRGRLNg 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 201 -RISSNGYIDRAASNLKSFYFSTAW---VDAKNSLRLnifsgkekTYQAW----NGVAEALLKTDRTYNISGQEQPGKPY 272
Cdd:TIGR01783 152 aRQDGDSFYDGAGEETRLGATATDWqldDRTLLRLGA--------YYQKErdrgGYGGLPASGGTSGRDLSSDRYLGTSS 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 273 PNETDNYTQTHYQLFYNHQFNQYWKANAAVFLtkgkgyyeeYRADQSLSNYGLPDYIANGDTTSSTDMV----RQEWLDN 348
Cdd:TIGR01783 224 NRNYDDREYLSYGLSLEYQFNDVWTGKQNLRY---------SYFDTDSNQVQASGYSSDGGLFGRSLTVvnvkQDRVQID 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 349 NFYGSIFSLQYKKEKtqFTFGGGWNQYDGKHFGNithavvQAAVPQN-YKWYGDLPAHKKD---------------LSLY 412
Cdd:TIGR01783 295 AGLDGEFETGPIEHD--LLLGVSYGQRTTNRFNN------TGYPSDNiYSLTATSSARTDIgdspkdralssttkaLNGV 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 413 AKFAQQLNEHWQLFADMQVRNVNYTINGFRDNPTLKVKNNYtfFNPKAGITYN-NNNWQVYASYARAGKEPNRDDFEAGK 491
Cdd:TIGR01783 367 ALQRILLADKWTLTLGGRYDSVDVKSNNGVAGSTGKRDDSQ--FTPSLGVAYKpTDDWSLYASYAESFKPGGYYPKGAGN 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 492 TQQP-KQEELNDVELGVE-KKNKLFSVGANLYYMQYHNQLVlignindVGSYTRTNIASSYRA---GIELQGTAVISNFL 566
Cdd:TIGR01783 445 SGDIlEPEKGKNYELGVRyDLGDSLLATAALFRITKDNQLV-------QDPVNGTFSVNAGKTrnrGVELEARGYLTPGL 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 567 NLAANLTISKNKishFTELIDDYDNGGTVTNKYNQTNISFSPAVIAGGSINFipvkhgEISLLSKYVSRQYMDNTSqqSR 646
Cdd:TIGR01783 518 SLSAGYTYTDAE---FTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGL------TLGGGVQYTGKAYVDGGN--TG 586
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 2532924251 647 SLNPYYVQDVRLTYTLSSidfLKTTTFILQLNNVFNKKyeangYTFSYYSGGLTTENYY 705
Cdd:TIGR01783 587 KVPSYTVVDLSVRYDLTK---KKNLTLALNVNNLFDRD-----YYTSGYRWGPSAYIYP 637
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
223-720 |
1.75e-20 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 95.22 E-value: 1.75e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 223 AWVDAKNSLRLNIFSGKEKTYQAWNGVAEALLKTDRTYNISGQ-EQPGKPYPNETDNYTQTHYQLFYNHQFNQYWKANAA 301
Cdd:pfam00593 1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYlGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 302 VfltKGKGYYEEYRADQSLSNYGLPDYiangDTTSSTDMVRQEWLDNNFYGSIFSLQYKkektqfTFGGGWNQYDGKHFG 381
Cdd:pfam00593 81 L---RLGLRYSSLDGDYTSNSSGLSGA----GDYLSDDRLYGLYGLDGDLELSLDLSHD------LLLGVELRTAGLDYR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 382 NITHAVVQAAVPQNYKWYGDLPAHKKDLSLYAKFAQQLNEHWQLFADMQVRNVNYTINGFRDNPTlKVKNNYTFFNPKAG 461
Cdd:pfam00593 148 RLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGD-NFSRSYSAFSPRLG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 462 ITYN-NNNWQVYASYARAGKEPNRDDFEAGKTQQP-----------KQEELNDVELGVEKKNKLFSVGANLYYMQYHNQL 529
Cdd:pfam00593 227 LVYKpTDNLSLYASYSRGFRAPSLGELYGSGSGGGggavaggnpdlKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLI 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 530 VLI--GNINDVGSYTRTNIASSYRAGIELQGTAVISNFLNLAANLTIsknkishfteliddYDNGGTVTNKYNQTNISFS 607
Cdd:pfam00593 307 TSDpdGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLGLSGGGYTY--------------TDADDDADADDTGNPLPNV 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 608 PAVIAGGSINFIPVKHG-EISLLSKYVSRQYM-DNTSQQSRSLNPYYVQDVRLTYTLSsidflKTTTFILQLNNVFNKKY 685
Cdd:pfam00593 373 PRHTANLGLTYDFPLGGwGARLGARYVGSGERrYGDAANTFKTPGYTLVDLSAGYRLN-----KNLTLRLGVNNLFDKYY 447
|
490 500 510
....*....|....*....|....*....|....*
gi 2532924251 686 EangytfsYYSGGLTTENYYFPMAPFNCMLGVNIR 720
Cdd:pfam00593 448 K-------RYYSSGGGNLGGYPGPGRTFYLGLSYK 475
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
43-151 |
9.78e-14 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 67.68 E-value: 9.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 43 EKAPFAKTNLARKDIEKNNVgQDLPFLLNQTPSVVINSDAGNGVGYtgIRIRGTDASRINVTLNGIPYNDAE--SQGTYF 120
Cdd:pfam07715 3 RDTPGSVSVVTAEDIEDQGA-TNLADALRGVPGVSVSSGGGGGGSS--ISIRGFGSNRVLVLVDGVPLNSGGggSVDLNS 79
|
90 100 110
....*....|....*....|....*....|.
gi 2532924251 121 VDLPDIAssanSIQIQRGVGTSSNGAGSFGG 151
Cdd:pfam07715 80 IDPEDIE----RVEVLKGPASALYGSGAIGG 106
|
|
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
435-605 |
3.04e-04 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 43.80 E-value: 3.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 435 NYTINGFRDNPTLKVKNNYTFFNPKAGITYN---NNNWQVYASYARAGKEPNRDDFEAGKTQQ---------P--KQEEL 500
Cdd:pfam14905 138 YTDIDGDSVTTNETFKRNYFNLFPSASLSYKlndNNSLQLSLYYRRIINRPSYWDLNPFRNYSdpynysqgnPnlKPEYT 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 501 NDVELGVEKKNKlFSVGANLYYMQYHNQLVLIGNIND-VGSYTRTNIASSYRAGIELQGTAVISNFLNLAANLTISKNKI 579
Cdd:pfam14905 218 NSFELGYTYKWK-LSLSLSYRYTNDVIQQTFITDDNDnVTYTTYENLGKSNSYGLELSASFNPTKWWSLNGNLNGYYNKY 296
|
170 180
....*....|....*....|....*.
gi 2532924251 580 SHFTELIDDYDNGGTVTNKYNQTNIS 605
Cdd:pfam14905 297 KIDGSLNSDFSNFGFNWNLNNTFTLP 322
|
|
| TonB-Xanth-Caul |
TIGR01782 |
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ... |
70-157 |
1.86e-03 |
|
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]
Pssm-ID: 273804 [Multi-domain] Cd Length: 845 Bit Score: 41.55 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2532924251 70 LNQTPSVVINSDAGNGVGytgIRIRGTDASRINVTLNG--IPYNDAESQGTYFVDLPdiASSANSIQIQRGVgTSSNGAG 147
Cdd:TIGR01782 47 LQRVPGVSIERDQGEGRY---VSVRGLGPSYNRTTLNGrtIASTDSGGRAFSLDLLP--SELVSGVEVYKTP-TADMDEG 120
|
90
....*....|
gi 2532924251 148 SFGGNINLST 157
Cdd:TIGR01782 121 GIGGTVDLRT 130
|
|
| |
