|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1004 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1389.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 1 MLNRLVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQR 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 81 MLRSVSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYMFTIEADG--MTLEERRTLL 158
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 159 DWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTA 238
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 239 EDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKAEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEI 318
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 319 KPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALG 398
Cdd:COG3696 321 VPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 399 MLVDAAVVVVENIVQHLEQEGSKK-KLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFAL 477
Cdd:COG3696 401 IIVDGAVVMVENILRRLEENRAAGtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 478 ISSLVLSLTVIPVLASFLLKK-VAHEDPWLPRKLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPEMDE 556
Cdd:COG3696 481 LGALLLSLTLVPVLASLLLRGkVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDE 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 557 GDIIVGIEKLPSVSLEETAALDLKIHQALMsQIPEITGVVARAGSDEIGLDPMGLNQTDTFLVLKPREEWKLA-NKEALI 635
Cdd:COG3696 561 GDLLVMATLPPGISLEESVELGQQVERILK-SFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGrTKEELI 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 636 ARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVQYLR 715
Cdd:COG3696 640 AEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLD 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 716 VVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLT 795
Cdd:COG3696 720 IRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIE 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 796 RESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIFL 875
Cdd:COG3696 800 VVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 876 ILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQG 955
Cdd:COG3696 880 LLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEG 959
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 2534433366 956 ARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:COG3696 960 ALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTL 1008
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1004 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 932.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 1 MLNRLVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQR 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 81 MLRSVSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYMFTIEA-------DG--MTL 151
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAeegarkkDGgaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 152 EERRTLLDWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRS 231
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 232 EGNIKTAEDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPT 311
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINKT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 312 LPAGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLG 391
Cdd:TIGR00914 320 LPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 392 glAIALGMLVDAAVVVVENIVQHLE----QEGSKKKL-PRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYF 466
Cdd:TIGR00914 400 --ALDFGLIVDGAVVIVENAHRRLAeaqhHHGRQLTLkERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 467 VPVAMTIVFALISSLVLSLTVIPVL-ASFLLKKVAHEDPWLPRKLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQ 545
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAvALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 546 VGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMSqIPEITGVVARAGSDEIGLDPMGLNQTDTFLVLKPREE 625
Cdd:TIGR00914 558 VGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKS-FPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 626 WK--LANKEALIARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDV 703
Cdd:TIGR00914 637 WPegKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADV 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 704 YTVENDGVQYLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDG 783
Cdd:TIGR00914 717 KVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLS 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 784 -----QSVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRA 858
Cdd:TIGR00914 797 edarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSA 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 859 AARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYF 938
Cdd:TIGR00914 877 TKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI 956
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2534433366 939 NQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:TIGR00914 957 RKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1004 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 901.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 5 LVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 85 VSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGIS-GGMAPVTTPLGEMYMFTIEADG--MTLEERRTLLDWV 161
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDgsYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 162 IRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDL 241
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 242 RSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPF 321
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 322 YNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLV 401
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 402 DAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSL 481
Cdd:pfam00873 400 DDAIVVVENIERVLEENG----LKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 482 VLSLTVIPVLASFLLKKVAHED-----PWLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPE 553
Cdd:pfam00873 476 LVALTLTPALCATLLKPRREPKhggffRWFNRMFDRLtrgYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 554 MDEGDIIVGIEKLPSVSLEETAALdLKIHQALMSQIPEITGVVARAGSDEIGlDPMGLNQTDTFLVLKPREEWKLANK-- 631
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRV-MKQVEKILKEKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERPGPEKsv 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 632 EALIARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGV 711
Cdd:pfam00873 634 QALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQ 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 712 QYLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETL 791
Cdd:pfam00873 714 PQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAF 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 792 ATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIG 871
Cdd:pfam00873 794 AKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALL 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 872 FIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRA-EGHDLVT 950
Cdd:pfam00873 874 VVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREqEGKSLEE 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 2534433366 951 CVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:pfam00873 954 AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTV 1007
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1003 |
1.85e-143 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 455.24 E-value: 1.85e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 17 LLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSKYGLVDVTVD 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 97 FEDGTDIYWARQQVSERLANIAGDLPSG-----ISGGMAPVTTPLgeMYMfTIEADGMTLEERRTLLDWVIRPALRAVPG 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEapdppVYRKANSADTPI--MYI-GLTSEEMPRGQLTDYAERVLAPKLSQING 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 172 VADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDLRSIVVSRKDG 251
Cdd:NF033617 169 VGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 252 NLA-RLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPFYNRAELVKK 330
Cdd:NF033617 249 GAPvRLGDVATVELGAENVRNRAWANGV-PAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 331 AVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLVDAAVVVVEN 410
Cdd:NF033617 328 SIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVEN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 411 IVQHLEqEGSKKklprLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSLVLSLTVIPV 490
Cdd:NF033617 408 IHRHIE-EGESP----LEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPM 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 491 LASFLLKKVAHEDPWLPR------KLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPEMDEGDIIVGIE 564
Cdd:NF033617 483 MCSRLLKANEKPGRFARAvdrffdGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQ 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 565 KLPSVSLEETAALDLKIHQALMSqIPEitgvVARAGSDEIGLDPMGLNQTDTFLVLKPREEwKLANKEALIARIREVLDQ 644
Cdd:NF033617 563 APQSISLDYMSAKMRDVEKILSS-DPE----VQSLTSFNGVGGNPGDNTGFGIINLKPWDE-RDVSAQEIIDRLRPKLAK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 645 MPGISYsFTQPIDmrvsEMIIGVRGDLAIKIF---GTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVQYLRVVVDRL 721
Cdd:NF033617 637 VPGMDL-FLFPLQ----DLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRD 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 722 SAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLTRESGPV 801
Cdd:NF033617 712 KAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPL 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 802 KIDREMGSRYSVVIANVTGRDLVGfveEARAKI--AAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIFLILFT 879
Cdd:NF033617 792 SLNHFNQFNSATLSFNLAPGVSLG---EAIEALdqAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAI 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 880 TFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQL-RAEGHDLVTCVTQGARR 958
Cdd:NF033617 869 QYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELqRHQGLSRREAIYQAAAL 948
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*
gi 2534433366 959 RLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITAT 1003
Cdd:NF033617 949 RLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGT 993
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
8-1004 |
6.58e-83 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 290.99 E-value: 6.58e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 8 FALSQRLFVLLAtallagfGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSK 87
Cdd:PRK09577 11 FAWVISLFIMLG-------GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 88 YGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLP-----SGISGGMAPVTTPLgeMYMFTIEADGMTLEERRTLLDWVI 162
Cdd:PRK09577 84 AGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPepvrrDGIQVEKAADNIQL--IVSLTSDDGRLTGVELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 163 RPALRAVPGVADVNALGGKvHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGE------VLLVRSEGNIK 236
Cdd:PRK09577 162 LQALRRVEGVGKVQFWGAE-YAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVpdsapiAATVFADAPLK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 237 TAEDLRSIVV-SRKDGNLARLGDVAQVRDGSvTRYGVVTK-DGKAEAveGLVLGLA-GANAQKVVEGVTQKLEDLKPTLP 313
Cdd:PRK09577 241 TPEDFGAIALrARADGSALYLRDVARIEFGG-NDYNYPSYvNGKTAT--GMGIKLApGSNAVATEKRVRATMDELSRYFP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 314 AGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGL 393
Cdd:PRK09577 318 PGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGM 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 394 AIALGMLVDAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTI 473
Cdd:PRK09577 398 VLAIGILVDDAIVVVENVERLMVEEG----LSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSL 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 474 VFALISSLVLSLTVIPVLASFLLKKVA--HEDP-----WLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAAGIY 543
Cdd:PRK09577 474 AVSIGFSAFLALSLTPALCATLLKPVDgdHHEKrgffgWFNRFVARStqrYATRVGAILKRPLRWLVVYGALTAAAALLF 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 544 TQVGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMSQIPeITGVVARAGSDEIGldpMGLNQTDTFLVLKPR 623
Cdd:PRK09577 554 TRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP-VAYTFALGGFNLYG---EGPNGGMIFVTLKDW 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 624 EEWKLANK--EALIARIREVLDQMPGIS-YSFTQP----------IDMRVSEmiigvRGDLAIKIFGTELGKLNELAAQI 690
Cdd:PRK09577 630 KERKAARDhvQAIVARINERFAGTPNTTvFAMNSPalpdlgstsgFDFRLQD-----RGGLGYAAFVAAREQLLAEGAKD 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 691 ETLMKTV-PGNQDVYTVENDgvqylrvvVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKIS 769
Cdd:PRK09577 705 PALTDLMfAGTQDAPQLKLD--------IDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLD 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 770 PAEFAALRITTSDGQSVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAevKLPTGYRISWG 849
Cdd:PRK09577 777 PDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA--TLPAGIGYAWS 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 850 GQFENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVL 929
Cdd:PRK09577 855 GQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAK 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2534433366 930 NGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:PRK09577 935 NAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATV 1009
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1004 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1389.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 1 MLNRLVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQR 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 81 MLRSVSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYMFTIEADG--MTLEERRTLL 158
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 159 DWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTA 238
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 239 EDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKAEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEI 318
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 319 KPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALG 398
Cdd:COG3696 321 VPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 399 MLVDAAVVVVENIVQHLEQEGSKK-KLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFAL 477
Cdd:COG3696 401 IIVDGAVVMVENILRRLEENRAAGtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 478 ISSLVLSLTVIPVLASFLLKK-VAHEDPWLPRKLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPEMDE 556
Cdd:COG3696 481 LGALLLSLTLVPVLASLLLRGkVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDE 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 557 GDIIVGIEKLPSVSLEETAALDLKIHQALMsQIPEITGVVARAGSDEIGLDPMGLNQTDTFLVLKPREEWKLA-NKEALI 635
Cdd:COG3696 561 GDLLVMATLPPGISLEESVELGQQVERILK-SFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGrTKEELI 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 636 ARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVQYLR 715
Cdd:COG3696 640 AEMREALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLD 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 716 VVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLT 795
Cdd:COG3696 720 IRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIE 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 796 RESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIFL 875
Cdd:COG3696 800 VVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 876 ILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQG 955
Cdd:COG3696 880 LLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEG 959
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 2534433366 956 ARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:COG3696 960 ALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTL 1008
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1004 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 932.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 1 MLNRLVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQR 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 81 MLRSVSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYMFTIEA-------DG--MTL 151
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAeegarkkDGgaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 152 EERRTLLDWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRS 231
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 232 EGNIKTAEDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPT 311
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINKT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 312 LPAGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLG 391
Cdd:TIGR00914 320 LPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 392 glAIALGMLVDAAVVVVENIVQHLE----QEGSKKKL-PRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYF 466
Cdd:TIGR00914 400 --ALDFGLIVDGAVVIVENAHRRLAeaqhHHGRQLTLkERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 467 VPVAMTIVFALISSLVLSLTVIPVL-ASFLLKKVAHEDPWLPRKLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQ 545
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAvALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 546 VGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMSqIPEITGVVARAGSDEIGLDPMGLNQTDTFLVLKPREE 625
Cdd:TIGR00914 558 VGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKS-FPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 626 WK--LANKEALIARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDV 703
Cdd:TIGR00914 637 WPegKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADV 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 704 YTVENDGVQYLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDG 783
Cdd:TIGR00914 717 KVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLS 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 784 -----QSVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRA 858
Cdd:TIGR00914 797 edarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSA 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 859 AARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYF 938
Cdd:TIGR00914 877 TKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI 956
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2534433366 939 NQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:TIGR00914 957 RKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1004 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 901.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 5 LVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRS 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 85 VSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGIS-GGMAPVTTPLGEMYMFTIEADG--MTLEERRTLLDWV 161
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQrPGISVIKTSLGPIMVLAVTSPDgsYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 162 IRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDL 241
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 242 RSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPF 321
Cdd:pfam00873 241 EKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 322 YNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLV 401
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 402 DAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSL 481
Cdd:pfam00873 400 DDAIVVVENIERVLEENG----LKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 482 VLSLTVIPVLASFLLKKVAHED-----PWLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPE 553
Cdd:pfam00873 476 LVALTLTPALCATLLKPRREPKhggffRWFNRMFDRLtrgYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 554 MDEGDIIVGIEKLPSVSLEETAALdLKIHQALMSQIPEITGVVARAGSDEIGlDPMGLNQTDTFLVLKPREEWKLANK-- 631
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRV-MKQVEKILKEKPEVESVFAVTGFAFSG-DNNGPNSGDAFISLKPWKERPGPEKsv 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 632 EALIARIREVLDQMPGISYSFTQPIDMRVSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGV 711
Cdd:pfam00873 634 QALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQ 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 712 QYLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETL 791
Cdd:pfam00873 714 PQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAF 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 792 ATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIG 871
Cdd:pfam00873 794 AKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALL 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 872 FIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRA-EGHDLVT 950
Cdd:pfam00873 874 VVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREqEGKSLEE 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 2534433366 951 CVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:pfam00873 954 AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTV 1007
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1003 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 762.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 4 RLVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLR 83
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 84 SVSKYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGI--------SGGMAPVttplgeMYmFTIEADGMTLEERR 155
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVeppgvtkvNPSDFPV------MV-LALSSDDLDELELS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 156 TLLDWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNI 235
Cdd:COG0841 155 DYAERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 236 KTAEDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAG 315
Cdd:COG0841 235 KTPEEFENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGK-PAVGLAIQKQPGANALEVADAVRAKLEELQASLPEG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 316 VEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAI 395
Cdd:COG0841 314 VELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 396 ALGMLVDAAVVVVENIVQHLEQegskkKLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVF 475
Cdd:COG0841 394 AIGIVVDDAIVVVENIERHMEE-----GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAI 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 476 ALISSLVLSLTVIPVLASFLLKKVAHEDP-----WLPR---KLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVG 547
Cdd:COG0841 469 ALLISLFVALTLTPALCARLLKPHPKGKKgrffrAFNRgfdRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 548 KTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMsQIPEITGVVARAGSdeiGLDPMGLNQTDTFLVLKPREEWK 627
Cdd:COG0841 549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILL-EVPEVESVFSVVGF---SGGGSGSNSGTIFVTLKPWDERD 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 628 LaNKEALIARIREVLDQMPGISYSFTQPidmrvSEMIIGVRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYTVE 707
Cdd:COG0841 625 R-SADEIIARLREKLAKIPGARVFVFQP-----PAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDL 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 708 NDGVQYLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVP 787
Cdd:COG0841 699 QLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVP 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 788 LETLATLTRESGPVKIDREMGSRYSVVIANVT-GRDLVGFVEEARaKIAAEVKLPTGYRISWGGQFENQQRAAARLTLVV 866
Cdd:COG0841 779 LSSVATIEEGTGPSSINRYNGQRSVTVSANLApGVSLGEALAAIE-ELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAF 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 867 PLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGH 946
Cdd:COG0841 858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGM 937
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 2534433366 947 DLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITAT 1003
Cdd:COG0841 938 SLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFST 994
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1003 |
1.85e-143 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 455.24 E-value: 1.85e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 17 LLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSKYGLVDVTVD 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 97 FEDGTDIYWARQQVSERLANIAGDLPSG-----ISGGMAPVTTPLgeMYMfTIEADGMTLEERRTLLDWVIRPALRAVPG 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEapdppVYRKANSADTPI--MYI-GLTSEEMPRGQLTDYAERVLAPKLSQING 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 172 VADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDLRSIVVSRKDG 251
Cdd:NF033617 169 VGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 252 NLA-RLGDVAQVRDGSVTRYGVVTKDGKaEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPFYNRAELVKK 330
Cdd:NF033617 249 GAPvRLGDVATVELGAENVRNRAWANGV-PAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 331 AVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLVDAAVVVVEN 410
Cdd:NF033617 328 SIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVVEN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 411 IVQHLEqEGSKKklprLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSLVLSLTVIPV 490
Cdd:NF033617 408 IHRHIE-EGESP----LEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPM 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 491 LASFLLKKVAHEDPWLPR------KLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPEMDEGDIIVGIE 564
Cdd:NF033617 483 MCSRLLKANEKPGRFARAvdrffdGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQ 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 565 KLPSVSLEETAALDLKIHQALMSqIPEitgvVARAGSDEIGLDPMGLNQTDTFLVLKPREEwKLANKEALIARIREVLDQ 644
Cdd:NF033617 563 APQSISLDYMSAKMRDVEKILSS-DPE----VQSLTSFNGVGGNPGDNTGFGIINLKPWDE-RDVSAQEIIDRLRPKLAK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 645 MPGISYsFTQPIDmrvsEMIIGVRGDLAIKIF---GTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVQYLRVVVDRL 721
Cdd:NF033617 637 VPGMDL-FLFPLQ----DLPGGAGSSLPQYQVtltPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRD 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 722 SAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLTRESGPV 801
Cdd:NF033617 712 KAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPL 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 802 KIDREMGSRYSVVIANVTGRDLVGfveEARAKI--AAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIFLILFT 879
Cdd:NF033617 792 SLNHFNQFNSATLSFNLAPGVSLG---EAIEALdqAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAI 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 880 TFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQL-RAEGHDLVTCVTQGARR 958
Cdd:NF033617 869 QYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELqRHQGLSRREAIYQAAAL 948
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*
gi 2534433366 959 RLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITAT 1003
Cdd:NF033617 949 RLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGT 993
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
5-1003 |
1.36e-106 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 357.12 E-value: 1.36e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 5 LVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRS 84
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 85 VSKY-GLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYM---FTIEADGMTLEERRTLLDW 160
Cdd:TIGR00915 81 SSDSdGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMvigLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 161 VIRPALRAVPGVADVNALGGKvHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLG-----EGGEV-LLVRSEGN 234
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQ-YAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGglpavPGQQLnATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 235 IKTAEDLRSIVV-SRKDGNLARLGDVAQVRDGSvTRYGVVTKDGKAEAVeGLVLGLA-GANAQKVVEGVTQKLEDLKPTL 312
Cdd:TIGR00915 240 LQTPEQFENILLkVNTDGSQVRLKDVARVELGG-ENYSISARFNGKPAS-GLAIKLAtGANALDTAKAVKAELAVLEPFF 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 313 PAGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGG 392
Cdd:TIGR00915 318 PQGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 393 LAIALGMLVDAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMT 472
Cdd:TIGR00915 398 MVLAIGLLVDDAIVVVENVERVMAEEG----LPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSIT 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 473 IVFALISSLVLSLTVIPVLASFLLKKVAHEDP---------WLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAA 540
Cdd:TIGR00915 474 IVSAMALSVLVALILTPALCATMLKPIEKGEHhekkggffgWFNRMFDSSthgYENGVGKILRRRGRYLLVYVLLVGGMV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 541 GIYTQVGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMS-QIPEITGVVARAGSDEIGldpMGLNQTDTFLV 619
Cdd:TIGR00915 554 FLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAkEKANVESVFTVNGFSFAG---RGQNMGMAFIR 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 620 LKPREEWKLANK--EALIARIREVLDQMP-GISYSFTQPidmRVSEMIIGV--------RGDLAIKIFGTELGKLNELAA 688
Cdd:TIGR00915 631 LKDWEERTGKENsvFAIAGRATGHFMQIKdAMVIAFVPP---AILELGNATgfdfflqdRAGLGHEALLQARNQLLGLAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 689 QIETLMKTVPGNQDvytvenDGVQYlRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKI 768
Cdd:TIGR00915 708 QNPALTRVRPNGLE------DEPQL-KIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARM 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 769 SPAEFAALRITTSDGQSVPLETLATLTRESGPVKIdremgSRYSVVIA-NVTGRDLVGFVE-EARAKIAAEV-KLPTGYR 845
Cdd:TIGR00915 781 SPEDINKWYVRNASGEMVPFSAFATVRWEYGSPQL-----ERYNGLPSmEILGSAAPGVSTgQAMAAMEAIAqKLPPGFG 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 846 ISWGGQFENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLG 925
Cdd:TIGR00915 856 FSWTGMSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIG 935
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2534433366 926 IAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITAT 1003
Cdd:TIGR00915 936 LSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTAT 1013
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
8-1004 |
6.58e-83 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 290.99 E-value: 6.58e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 8 FALSQRLFVLLAtallagfGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSK 87
Cdd:PRK09577 11 FAWVISLFIMLG-------GIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 88 YGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLP-----SGISGGMAPVTTPLgeMYMFTIEADGMTLEERRTLLDWVI 162
Cdd:PRK09577 84 AGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPepvrrDGIQVEKAADNIQL--IVSLTSDDGRLTGVELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 163 RPALRAVPGVADVNALGGKvHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGE------VLLVRSEGNIK 236
Cdd:PRK09577 162 LQALRRVEGVGKVQFWGAE-YAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVpdsapiAATVFADAPLK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 237 TAEDLRSIVV-SRKDGNLARLGDVAQVRDGSvTRYGVVTK-DGKAEAveGLVLGLA-GANAQKVVEGVTQKLEDLKPTLP 313
Cdd:PRK09577 241 TPEDFGAIALrARADGSALYLRDVARIEFGG-NDYNYPSYvNGKTAT--GMGIKLApGSNAVATEKRVRATMDELSRYFP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 314 AGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGL 393
Cdd:PRK09577 318 PGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGM 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 394 AIALGMLVDAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTI 473
Cdd:PRK09577 398 VLAIGILVDDAIVVVENVERLMVEEG----LSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSL 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 474 VFALISSLVLSLTVIPVLASFLLKKVA--HEDP-----WLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAAGIY 543
Cdd:PRK09577 474 AVSIGFSAFLALSLTPALCATLLKPVDgdHHEKrgffgWFNRFVARStqrYATRVGAILKRPLRWLVVYGALTAAAALLF 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 544 TQVGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMSQIPeITGVVARAGSDEIGldpMGLNQTDTFLVLKPR 623
Cdd:PRK09577 554 TRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP-VAYTFALGGFNLYG---EGPNGGMIFVTLKDW 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 624 EEWKLANK--EALIARIREVLDQMPGIS-YSFTQP----------IDMRVSEmiigvRGDLAIKIFGTELGKLNELAAQI 690
Cdd:PRK09577 630 KERKAARDhvQAIVARINERFAGTPNTTvFAMNSPalpdlgstsgFDFRLQD-----RGGLGYAAFVAAREQLLAEGAKD 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 691 ETLMKTV-PGNQDVYTVENDgvqylrvvVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKIS 769
Cdd:PRK09577 705 PALTDLMfAGTQDAPQLKLD--------IDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLD 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 770 PAEFAALRITTSDGQSVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAevKLPTGYRISWG 849
Cdd:PRK09577 777 PDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA--TLPAGIGYAWS 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 850 GQFENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVL 929
Cdd:PRK09577 855 GQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAK 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2534433366 930 NGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:PRK09577 935 NAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATV 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
17-1000 |
8.60e-77 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 273.14 E-value: 8.60e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 17 LLATAL-LAGFgwYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSKYGLVDVTV 95
Cdd:PRK10614 16 LLSLAItLCGI--LGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIIL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 96 DFEDGTDIYWARQQVSERLANIAGDLPSGISG-----GMAPVTTPLgeMYMfTIEADGMTLEERRTLLDWVIRPALRAVP 170
Cdd:PRK10614 94 QFDFDRDINGAARDVQAAINAAQSLLPSGMPSrptyrKANPSDAPI--MIL-TLTSDTYSQGQLYDFASTQLAQTISQID 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 171 GVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDLRSIVVSRKD 250
Cdd:PRK10614 171 GVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIHYNN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 251 GNLARLGDVAQVRDgSVTRYGVVTKDGKAEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPFYNRAELVKK 330
Cdd:PRK10614 251 GAAVRLGDVATVTD-SVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPTIRA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 331 AVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLVDAAVVVVEN 410
Cdd:PRK10614 330 SLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLEN 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 411 IVQHLEQeGSKKklprLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSLVLSLTVIPV 490
Cdd:PRK10614 410 ISRHLEA-GMKP----LQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPM 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 491 LASFLLKKVAHEDPWLPR-------KLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTFLPEMDEGDIIVGI 563
Cdd:PRK10614 485 MCAWLLKSSKPREQKRLRgfgrmlvALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFI 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 564 EKLPSVSLEetaALDLKIhQALMSQI---PEITGVVARAGSDEIgldpmglNQTDTFLVLKPREEwKLANKEALIARIRE 640
Cdd:PRK10614 565 QADQSISFQ---AMRGKL-QDFMKIIrddPAVDNVTGFTGGSRV-------NSGMMFITLKPLSE-RSETAQQVIDRLRV 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 641 VLDQMPGISYSFtqpidMRVSEMIIGVRGDLAI---KIFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVQYLRVV 717
Cdd:PRK10614 633 KLAKEPGANLFL-----MAVQDIRVGGRQSNASyqyTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALT 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 718 VDRLSAGRYGLSVEDVQDALRAQIeGQRA-GTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLTR 796
Cdd:PRK10614 708 YDRDTMARLGIDVQAANSLLNNAF-GQRQiSTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQP 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 797 ESGPVKIDREMGSRYSVVIANV-TGRDLvgfvEEARAKI---AAEVKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGF 872
Cdd:PRK10614 787 ANAPLSVNHQGLSAASTISFNLpTGKSL----SDASAAIeraMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIAT 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 873 IFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGH-DLVTC 951
Cdd:PRK10614 863 VYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNlTAQEA 942
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 2534433366 952 VTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLI 1000
Cdd:PRK10614 943 IFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLV 991
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
5-1003 |
7.11e-74 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 264.77 E-value: 7.11e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 5 LVQFALSQRLFVLLATALLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRS 84
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 85 VSKY-GLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPlGEMYMFTI---EADGMTleERRTLLDW 160
Cdd:PRK10555 81 QSSGtGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKT-GDTNILTIafvSTDGSM--DKQDIADY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 161 V---IRPALRAVPGVADVNALGGKvHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEV------LLVRS 231
Cdd:PRK10555 158 VasnIQDPLSRVNGVGDIDAYGSQ-YSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVdkqalnATINA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 232 EGNIKTAEDLRSIVVS-RKDGNLARLGDVAQVRDGSvTRYGVVTK-DGKAEAveGLVLGLA-GANAQKVVEGVTQKLEDL 308
Cdd:PRK10555 237 QSLLQTPEQFRDITLRvNQDGSEVTLGDVATVELGA-EKYDYLSRfNGKPAS--GLGVKLAsGANEMATAKLVLNRLDEL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 309 KPTLPAGVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLM 388
Cdd:PRK10555 314 AQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 389 SLGGLAIALGMLVDAAVVVVENIVQHLEQEGSKkklPRlhivlRAVREVSVPVSA---GI-LIIITVFLPLLTLQGLEGK 464
Cdd:PRK10555 394 TMFAMVLAIGLLVDDAIVVVENVERIMSEEGLT---PR-----EATRKSMGQIQGalvGIaMVLSAVFVPMAFFGGTTGA 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 465 YFVPVAMTIVFALISSLVLSLTVIPVLASFLLKKVA----HEDP----WLPRKLLKV---YEPVLAWALKKQRIVFVAAA 533
Cdd:PRK10555 466 IYRQFSITIVSAMVLSVLVAMILTPALCATLLKPLKkgehHGQKgffgWFNRMFNRNaerYEKGVAKILHRSLRWILIYV 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 534 LLLVAAAGIYTQVGKTFLPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMSQIPE-ITGVVARAGSDEIGldpMGLN 612
Cdd:PRK10555 546 LLLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDnVMSVFATVGSGPGG---NGQN 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 613 QTDTFLVLKPREEWKLANKE--ALIARIREVLDqmpgisysftqpidmRVSEMIIGVRGDLAIKIFGTELGKLNE----- 685
Cdd:PRK10555 623 VARMFIRLKDWDERDSKTGTsfAIIERATKAFN---------------KIKEARVIASSPPAISGLGSSAGFDMElqdha 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 686 ------LAAQIETLMKTVPGNQDVYTVENDGVQ---YLRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRI 756
Cdd:PRK10555 688 gaghdaLMAARNQLLALAAKNPELTRVRHNGLDdspQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVK 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 757 PIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLTRESGPVKIDREMGsrYSVViaNVTGRDLVGfVEEARAKIAA 836
Cdd:PRK10555 768 KVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNG--YSAV--EIVGEAAPG-VSTGTAMDIM 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 837 E---VKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLS 913
Cdd:PRK10555 843 EslvKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLEND 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 914 VPASVGFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAI 993
Cdd:PRK10555 923 VYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGT 1002
|
1050
....*....|
gi 2534433366 994 VVIGGLITAT 1003
Cdd:PRK10555 1003 GVMGGMISAT 1012
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
13-1000 |
1.59e-70 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 255.04 E-value: 1.59e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 13 RLFVLLATA--------LLAGFgwYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRS 84
Cdd:PRK10503 14 RLFILRPVAttllmvaiLLAGI--IGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 85 VSKYGLVDVTVDFEDGTDIYWARQQVSERLaNIA-----GDLPS-GISGGMAPVTTPlgeMYMFTIEADGMTLEERRTLL 158
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAI-NAAtnllpSDLPNpPVYSKVNPADPP---IMTLAVTSTAMPMTQVEDMV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 159 DWVIRPALRAVPGVADVNALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTA 238
Cdd:PRK10503 168 ETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 239 EDLRSIVVSRKDGNLARLGDVAQVRDGSVTRYgVVTKDGKAEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEI 318
Cdd:PRK10503 248 EEYRQLIIAYQNGAPIRLGDVATVEQGAENSW-LGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKV 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 319 KPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALG 398
Cdd:PRK10503 327 TVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATG 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 399 MLVDAAVVVVENIVQHLEQeGSKKklprLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALI 478
Cdd:PRK10503 407 FVVDDAIVVIENISRYIEK-GEKP----LAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAIL 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 479 SSLVLSLTVIPVLASFLLK--------KVAHEDPWLPRKLLKVYEPVLAWALKKQRIVFVAAALLLVAAAGIYTQVGKTF 550
Cdd:PRK10503 482 ISAVVSLTLTPMMCARMLSqeslrkqnRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGF 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 551 LPEMDEGDIIVGIEKLPSVSLEETAALDLKIHQALMsQIPEITGVVARAGSDeiGLDPmGLNQTDTFLVLKPREEwKLAN 630
Cdd:PRK10503 562 FPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVIL-QDPAVQSLTSFVGVD--GTNP-SLNSARLQINLKPLDE-RDDR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 631 KEALIARIREVLDQMPGISYsFTQP-----IDMRVSemiigvRGDLAIKIFGTELGKLNELAAQIETLMKTVPGNQDVYT 705
Cdd:PRK10503 637 VQKVIARLQTAVAKVPGVDL-YLQPtqdltIDTQVS------RTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSS 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 706 VENDGVQYLRVVVDRLSAGRYGLSVEDVQDALRAQIeGQR-AGTVIDGNRRIPIVLRGPDSVKISPAEFAALRITTSDGQ 784
Cdd:PRK10503 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAF-GQRlISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGG 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 785 SVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAARLTL 864
Cdd:PRK10503 789 VVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVW 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 865 VVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSY-FNQLRA 943
Cdd:PRK10503 869 LIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFaLAAERE 948
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 2534433366 944 EGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLI 1000
Cdd:PRK10503 949 QGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLI 1005
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
22-1003 |
1.78e-69 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 251.68 E-value: 1.78e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 22 LLAGFGWYAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVSKYGLVDVTVDFEDGT 101
Cdd:PRK09579 20 LIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIISIYARIGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 102 DIYWARQQVSERLANIAGDLPSGISGgmaPVTTPLGE-----MYMfTIEADGMTLEERRTLLDWVIRPALRAVPGVADVN 176
Cdd:PRK09579 100 DSDRLFTELLAKANEVKNQLPQDAED---PVLSKEAAdasalMYI-SFYSEEMSNPQITDYLSRVIQPKLATLPGMAEAE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 177 ALGGKVHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEVLLVRSEGNIKTAEDLRSIVVSRKDGNLARL 256
Cdd:PRK09579 176 ILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVKTSGDSRVLL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 257 GDVAQVRDGSVTRYGVVTKDGKAEAVEGlVLGLAGANAQKVVEGVTQKLEDLKPTLPAGVEIKPFYNRAELVKKAVGTVS 336
Cdd:PRK09579 256 GDVARVEMGAENYDSISSFDGIPSVYIG-IKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFIQASIDEVV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 337 TALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLAIALGMLVDAAVVVVENIVQHLE 416
Cdd:PRK09579 335 KTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIE 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 417 QegskKKLPrLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIVFALISSLVLSLTVIPVLASFLL 496
Cdd:PRK09579 415 E----GKSP-FDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLL 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 497 KK------VAHEDPWLPRKLLKVYEPVLAWALKKQRI--VFVAAALLLVAAAGIYTQvgKTFLPEMDEGdIIVGIEKLPs 568
Cdd:PRK09579 490 RHeenpsgLAHRLDRLFERLKQRYQRALHGTLNTRPVvlVFAVIVLALIPVLLKFTQ--SELAPEEDQG-IIFMMSSSP- 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 569 vsleETAALD-LKIHQA----LMSQIPEITGVVARAGSDeigldpmGLNQTDTFLVLKPREEWKLANKEaLIARIREVLD 643
Cdd:PRK09579 566 ----QPANLDyLNAYTDeftpIFKSFPEYYSSFQINGFN-------GVQSGIGGFLLKPWNERERTQME-LLPLVQAKLE 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 644 QMPGIS-YSFTQPIDMRVSE-----MIIGVRGDlaikiFGTELGKLNELAAQIETLMKTVPGNQDVYTVENDGVqylrVV 717
Cdd:PRK09579 634 EIPGLQiFGFNLPSLPGTGEglpfqFVINTAND-----YESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVV----VD 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 718 VDRLSAGRYGLSVEDVQDALRAQI-EGQRAGTVIDGnRRIPIVLRGPDSVKISPAEFAALRITTSDGQSVPLETLATLTR 796
Cdd:PRK09579 705 IDRAKAAQMGVSMQDLGGTLATLLgEGEINRFTIDG-RSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSD 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 797 ESGPvkidREMGSRYSVVIANVTGRDLVGFVE--EARAKIAAEvKLPTGYRISWGGQFENQQRAAARLTLVVPLAIGFIF 874
Cdd:PRK09579 784 RARP----RQLNQFQQLNSAIISGFPIVSMGEaiETVQQIARE-EAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIF 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 875 LILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAE-GHDLVTCVT 953
Cdd:PRK09579 859 LVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEqGLSRREAIE 938
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|
gi 2534433366 954 QGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITAT 1003
Cdd:PRK09579 939 EAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGT 988
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
8-1004 |
8.90e-69 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 250.21 E-value: 8.90e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 8 FALSQRLFVLLATALlagfgwyAFRNLPIDAFPDVSSTQVKVIMKAPGMTPEEIESRIAGPIEVEMLGIPRQRMLRSVS- 86
Cdd:PRK15127 11 FAWVIAIIIMLAGGL-------AILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSd 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 87 KYGLVDVTVDFEDGTDIYWARQQVSERLANIAGDLPSGISGGMAPVTTPLGEMYMFT--IEADG-MTLEERRTLLDWVIR 163
Cdd:PRK15127 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVgvINTDGtMTQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 164 PALRAVPGVADVNALGGKvHSFEVVPDPVKLAALGVSTAQLKSAIEANNRNDGAGRLGEGGEV------LLVRSEGNIKT 237
Cdd:PRK15127 164 DPISRTSGVGDVQLFGSQ-YAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVkgqqlnASIIAQTRLTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 238 AEDLRSIVVS-RKDGNLARLGDVAQVRDGSvTRYGVVTK-DGKAEAveGLVLGLA-GANAQKVVEGVTQKLEDLKPTLPA 314
Cdd:PRK15127 243 TEEFGKILLKvNQDGSRVRLRDVAKIELGG-ENYDIIAEfNGQPAS--GLGIKLAtGANALDTAAAIRAELAKMEPFFPS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 315 GVEIKPFYNRAELVKKAVGTVSTALIEATVIVLVLLGAFLGNVRAAVAVAVILPLSALSTFILMRSVGMSANLMSLGGLA 394
Cdd:PRK15127 320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 395 IALGMLVDAAVVVVENIVQHLEQEGskkkLPRLHIVLRAVREVSVPVSAGILIIITVFLPLLTLQGLEGKYFVPVAMTIV 474
Cdd:PRK15127 400 LAIGLLVDDAIVVVENVERVMAEEG----LPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 475 FALISSLVLSLTVIPVLASFLLKKVAHED---------PWLPRKLLKV---YEPVLAWALKKQRIVFVAAALLLVAAAGI 542
Cdd:PRK15127 476 SAMALSVLVALILTPALCATMLKPIAKGDhgegkkgffGWFNRMFEKSthhYTDSVGNILRSTGRYLVLYLIIVVGMAYL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 543 YTQVGKTFLPEMDEGdIIVGIEKLPSVSLEE--TAALDLKIHQALMSQIPEITGVVARAGsdeIGLDPMGLNQTDTFLVL 620
Cdd:PRK15127 556 FVRLPSSFLPDEDQG-VFLTMVQLPAGATQErtQKVLNEVTDYYLTKEKNNVESVFAVNG---FGFAGRGQNTGIAFVSL 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 621 KPREEWKLA-NK-EALIARIREVLDQMP-GISYSFTQPIDMRVS-------EMIIgvRGDLAIKIFGTELGKLNELAAQI 690
Cdd:PRK15127 632 KDWADRPGEeNKvEAITMRATRAFSQIKdAMVFAFNLPAIVELGtatgfdfELID--QAGLGHEKLTQARNQLLGEAAKH 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 691 ETLMKTVPGNQdvytvENDGVQYlRVVVDRLSAGRYGLSVEDVQDALRAQIEGQRAGTVIDGNRRIPIVLRGPDSVKISP 770
Cdd:PRK15127 710 PDMLVGVRPNG-----LEDTPQF-KIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLP 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 771 AEFAALRITTSDGQSVPLETLATLTRESGPVKIDREMGSRYSVVIANVTGRDLVGFVEEARAKIAAevKLPTGYRISWGG 850
Cdd:PRK15127 784 DDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELAS--KLPTGVGYDWTG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 851 QFENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPASVGFIALLGIAVLN 930
Cdd:PRK15127 862 MSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKN 941
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2534433366 931 GVVLVSYFNQL-RAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGSEIQRPLAIVVIGGLITATA 1004
Cdd:PRK15127 942 AILIVEFAKDLmDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATV 1016
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
810-1002 |
2.69e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 64.50 E-value: 2.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 810 RYSVVIANVTGRDLVGFVEEARAKIAAEVKlPTGYRISWGGQF----ENQQRAAARLTLVVPLAIGFIFLILFTTFGSVR 885
Cdd:COG1033 552 RVTVRLKDLDSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSAvlfaAINESVIESQIRSLLLALLLIFLLLLLAFRSLR 630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 886 QALLVL--SNIPFALVGGIVGLwvTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPV 963
Cdd:COG1033 631 LGLISLipNLLPILLTFGLMGL--LGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAI 708
|
170 180 190
....*....|....*....|....*....|....*....
gi 2534433366 964 LMTAAITAFSLVPLLFTSGPgseIQRPLAIVVIGGLITA 1002
Cdd:COG1033 709 LFTSLTLAAGFGVLLFSSFP---PLADFGLLLALGLLVA 744
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
826-1002 |
2.83e-10 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 64.50 E-value: 2.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 826 FVEEARAKIAAEVKLPTGYRISWGGQFENQQRAAAR--LTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVG--G 901
Cdd:COG1033 182 VVAEIRAIIAKYEDPGVEVYLTGFPVLRGDIAEAIQsdLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWtlG 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 902 IVGLwvTGEYLSVPASVGFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFT- 980
Cdd:COG1033 262 LMGL--LGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSd 339
|
170 180
....*....|....*....|..
gi 2534433366 981 SGPGSEiqrpLAIVVIGGLITA 1002
Cdd:COG1033 340 IPPIRD----FGIVAAIGVLLA 357
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
810-1002 |
1.07e-05 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 49.38 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 810 RYSVVIANVTGrDLVGFVEEARAKIAAEVK--LPTGYRISWGGQ-------FENQQRAAARLTLVvplAIGFIFLILFTT 880
Cdd:COG2409 114 KAALVTVTLDG-DAGDEAAEAVDALRDAVAaaPAPGLTVYVTGPaalaadlNEAFEEDLGRAELI---TLPVALVVLLLV 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 881 FGSVRQALLVLSNIPFALVGGIVGLWVTGEYLSVPA-SVGFIALLGIAVlnGV----VLVSYFNQLRAEGHDLVTCVTQG 955
Cdd:COG2409 190 FRSLVAALLPLLTAGLAVGVALGLLALLAAFTDVSSfAPNLLTMLGLGV--GIdyalFLVSRYREELRAGEDREEAVARA 267
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2534433366 956 ARRRLRPVLMTAAITAFSLVPLLFTsgpGSEIQRPLAIVVIGGLITA 1002
Cdd:COG2409 268 VATAGRAVLFSGLTVAIALLGLLLA---GLPFLRSMGPAAAIGVAVA 311
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
239-495 |
2.59e-05 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 48.32 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 239 EDLRSIVVSRKDGNLARLGDVAQVRDGSVTRyGVVTKDGKAEAVEGLVLGLAGANAQKVVEGVTQKLEDLKPtlPAGVEI 318
Cdd:COG1033 511 GDPKYYALPESRELLAQLLLLLSSPPGDDLS-RFVDEDYSAARVTVRLKDLDSEEIKALVEEVRAFLAENFP--PDGVEV 587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 319 KP------FYNRAELVKKAvGTVSTALieATVIVLVLLGAFLGNVRAAVAVavILP--LSALSTFILMRSVGMSANLMSL 390
Cdd:COG1033 588 TLtgsavlFAAINESVIES-QIRSLLL--ALLLIFLLLLLAFRSLRLGLIS--LIPnlLPILLTFGLMGLLGIPLNIATA 662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 391 GGLAIALGMLVDAAVVVVENIVQHLEQEGSKKKlprlhIVLRAVREVSVPVSAGILIIITVFLPLLTLQglegkyFVPVA 470
Cdd:COG1033 663 VVASIALGIGVDYTIHFLSRYREERRKGGDLEE-----AIRRALRTTGKAILFTSLTLAAGFGVLLFSS------FPPLA 731
|
250 260
....*....|....*....|....*...
gi 2534433366 471 ---MTIVFALISSLVLSLTVIPVLASFL 495
Cdd:COG1033 732 dfgLLLALGLLVALLAALLLLPALLLLL 759
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
853-1002 |
4.37e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 44.46 E-value: 4.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 853 ENQQRAAARLTLVVPLAIGFIFLILFTTFGSVRqaLLVLSNIPFAlVGGIVGLWVTG---EYLSVpASVGF-IALLGIAV 928
Cdd:COG4258 242 AAAQQIKHDISTIGLISLLGILLLLLLVFRSLR--PLLLGLLPVA-VGALAGLAAVSlvfGSVHG-ITLGFgSSLIGVAV 317
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2534433366 929 LNGvvlVSYFNQLRAEGHdlvTCVTQGARRRLRPVLMTAAITAFSLVPLLFTsgpGSEIQRPLAIVVIGGLITA 1002
Cdd:COG4258 318 DYS---LHYLTHRRAAGE---WDPRAALRRIWPTLLLGLLTTVLGYLALLFS---PFPGLRQLGVFAAAGLLAA 382
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
829-981 |
5.58e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 43.43 E-value: 5.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 829 EARAKIAAEVKLPTGYRISWGG---QFENQQRAAAR-LTLVVPLAIGFIFLILFTTFGSVRQALLVLSNIPFALVG--GI 902
Cdd:pfam03176 107 AAVRDAVEQAPPPEGLKAYLTGpaaTVADLRDAGDRdLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAaqGL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 903 VGLWVTGEYLSVPASV---GFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLF 979
Cdd:pfam03176 187 VAILAHILGIGLSTFAlnlLVVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSF 266
|
..
gi 2534433366 980 TS 981
Cdd:pfam03176 267 AR 268
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
684-1004 |
1.21e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 42.90 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 684 NELAAQIETLMKTVPGNqDVytVENDGVQYLRVVVDRLSAGRYGLSVEDVQDALRAqiegqragtvIDGNRRIPIVLRGp 763
Cdd:TIGR00921 50 REFGTSTKTLLVVIEGD-DV--TRKPVLDYMRRLEQRLREKPYVTNVRSAADIMRQ----------IPGNFPLPVTMPE- 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 764 dsVKISPAEFAalriTTSDGQSVPLETLATLTresgpVKIDREMGSRYSVVIANVTGRDLvgfvEEARAKIAAEVKLPTG 843
Cdd:TIGR00921 116 --VRPLMSEYP----RSKEMFLSKDHTVAIII-----VQLKSDADYKQVVPIYNDVERSL----ERTNPPSGKFLDVTGS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 844 YRISWggQFENQQRAAARLTLVVPLAIgfIFLILFTTFGSVRQALLVLSNIPFALVggivglWVTG--EYLSVPASV--- 918
Cdd:TIGR00921 181 PAINY--DIEREFGKDMGTTMAISGIL--VVLVLLLDFKRWWRPLLPLVIILFGVA------WVLGimGWLGIPLYAttl 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2534433366 919 -GFIALLGIAVLNGVVLVSYFNQLRAEGHDLVTCVTQGARRRLRPVLMTAAITAFSLVPLLFTSGPGseIQRpLAIVVIG 997
Cdd:TIGR00921 251 lAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPM--VSE-FGLGLVA 327
|
....*..
gi 2534433366 998 GLITATA 1004
Cdd:TIGR00921 328 GLITAYL 334
|
|
| |
