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Conserved domains on  [gi|2537726000|ref|WP_294193852|]
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dicarboxylate/amino acid:cation symporter [uncultured Cloacibacillus sp.]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
7-378 4.76e-63

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 206.99  E-value: 4.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   7 LPMKLLLGVIAGIAVGQFAGVALMNVVVTVRYILGQLILFCVPLIIiGFIAPSITRLGN--NASKMLGVAVTIAYISSIG 84
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAAWLKPLGDLFIRLLKMIIVPLIF-ASIISGIASLGDgkKLGKLGGKTLLYFLVTTAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  85 AALFSMAAGYIMIPNLSIVTNVEGLQALPDL-------VFKLDIPPIM-------SVMSALALSMCLGLAAAW--TKAKS 148
Cdd:pfam00375  80 AALIGLLVANVFQPGSGLALIAASLKEAKAAeapslldFILNIIPSNIfealaegNVLAVIVFAILFGIALAAlgEKGEP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 149 ITNALEEFQLIVLAIVTKIVIpLLPFFIAFTFCSLSYEgSITKQLPVFIQVILIVMAGHYIWMALLYGLAG-IYTGKNPF 227
Cdd:pfam00375 160 LLNFIESLQEVMMKVIGWVMK-LAPIGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIkFLGKVNPF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 228 DIIKNYGPAYITAVGTMSSAATLAVALRCAKKsEPPLRDDMVDFGIPLFANIHLCGSVLTEVFFVMTISKILYGAIpPIE 307
Cdd:pfam00375 238 KFLKKMLPALLTAFSTASSAATLPVTLECAEK-NLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDL-SFG 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537726000 308 TMVLFCLLLGIFAIAAPGVPGGTVMAsLGLITGILGFDDSGTALMLTIFALQDSFGTACNVTGDGALTLML 378
Cdd:pfam00375 316 QQLTLVLTATLASIGAAGVPGGGLVA-LGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIV 385
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
7-378 4.76e-63

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 206.99  E-value: 4.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   7 LPMKLLLGVIAGIAVGQFAGVALMNVVVTVRYILGQLILFCVPLIIiGFIAPSITRLGN--NASKMLGVAVTIAYISSIG 84
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAAWLKPLGDLFIRLLKMIIVPLIF-ASIISGIASLGDgkKLGKLGGKTLLYFLVTTAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  85 AALFSMAAGYIMIPNLSIVTNVEGLQALPDL-------VFKLDIPPIM-------SVMSALALSMCLGLAAAW--TKAKS 148
Cdd:pfam00375  80 AALIGLLVANVFQPGSGLALIAASLKEAKAAeapslldFILNIIPSNIfealaegNVLAVIVFAILFGIALAAlgEKGEP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 149 ITNALEEFQLIVLAIVTKIVIpLLPFFIAFTFCSLSYEgSITKQLPVFIQVILIVMAGHYIWMALLYGLAG-IYTGKNPF 227
Cdd:pfam00375 160 LLNFIESLQEVMMKVIGWVMK-LAPIGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIkFLGKVNPF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 228 DIIKNYGPAYITAVGTMSSAATLAVALRCAKKsEPPLRDDMVDFGIPLFANIHLCGSVLTEVFFVMTISKILYGAIpPIE 307
Cdd:pfam00375 238 KFLKKMLPALLTAFSTASSAATLPVTLECAEK-NLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDL-SFG 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537726000 308 TMVLFCLLLGIFAIAAPGVPGGTVMAsLGLITGILGFDDSGTALMLTIFALQDSFGTACNVTGDGALTLML 378
Cdd:pfam00375 316 QQLTLVLTATLASIGAAGVPGGGLVA-LGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIV 385
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
6-377 9.47e-24

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 101.73  E-value: 9.47e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   6 SLPMKLLLGVIAGIAVGQFAGVALMNVVVTVRYILGQLILFCVPLIIIGFIAPSITRLGNNAS--KMLGVAVTIAYISSI 83
Cdd:COG1301     4 SLTLQILIALVLGILLGLLLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKlgRIGGKTLLYFLVTTT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  84 GAALFSMAAGYIMIP------NLSIVTNVEGLQALPDLVFKLDIPPiMSVMSALA---------LSMCLGLAAA--WTKA 146
Cdd:COG1301    84 IALVIGLVVANLFQPgaglnlDLADAAAAEAAEAPSLLDFLLNIIP-SNIFEAFAegnmlqiifFAILFGIALAalGEKG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 147 KSITNALEEFQLIVLAIVtKIVIPLLPF--FIAFTFCSLSYEGSITKQLPVFIQVILIVMAGHyiWMALLYGLAGIYTGK 224
Cdd:COG1301   163 KPLLDFFESLSEVMFKIV-GWVMKLAPIgvFALIAATVAKYGLDALGSLGKLVLTVYLALLLH--LFVVLPLILRLLTGL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 225 NPFDIIKNYGPAYITAVGTMSSAATLAVALRCAKKsEPPLRDDMVDFGIPLFANIHLCGSVLTEVFFVMTISKiLYGAIP 304
Cdd:COG1301   240 SPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEE-KLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQ-AYGIDL 317

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537726000 305 PIETMVLFCLLLGIFAIAAPGVPGGTvMASLGLITGILGFDDSGTALMLTIFALQDSFGTACNVTGDGALTLM 377
Cdd:COG1301   318 SLGQQLTIVLTAVLASIGAAGVPGAG-LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVV 389
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 5-338 5.56e-05

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 44.85  E-value: 5.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   5 TSLPMKLLLGVIAGIAVGQFAGVALMNVVvtvryILGQLI---LFCV-PLIIIGFIAPSITRLGNNASKMLGVAVTIAYI 80
Cdd:PRK13628   14 GSLVKQILIGLVLGILLALLSPPAAEAVG-----LLGTLFvgaLKAVaPILVFVLVMASIANHKKGQKTNIRPILVLYLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  81 SSIGAALFSMAAGYIMIPNLSIVTNVEGLQA-------LPDLVFKLDIPPIMSVMSA-----LALSMCLGLA--AAWTKA 146
Cdd:PRK13628   89 GTFLAALVAVVASFLFPSTLVLVASAADISPpqgivevLKTLLLSLVDNPINALLNAnyigiLAWAIGLGLAlrHASDTT 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 147 KSITNALEEfqlIVLAIVtKIVIPLLPFFIaFTFCSLSYEGSITKQLPVFIQvILIVMAGHYIWMALLYG--LAGIYTGK 224
Cdd:PRK13628  169 KNVVNDLSE---AVSQIV-KWVIRFAPIGI-FGLVASTLAETGFSALAGYAQ-LLAVLVGCMLFVALVVNplIVFWKIRR 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 225 NP----FDIIKNYGpayITAVGTMSSAATLAVALRCAKKSEppLRDDMVDFGIPLFANIHLCGSVLTevFFVMTISKILY 300
Cdd:PRK13628  243 NPyplvFTCLRESG---VTAFFTRSSAANIPVNMALCEKLG--LDEDTYSVSIPLGATINMAGAAIT--ITVLTLAAVHT 315

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 2537726000 301 GAIPP-IETMVLFCLLLGIFAIAAPGVPGGtvmaSLGLI 338
Cdd:PRK13628  316 LGIPVdLPTALLLSVVAAISACGASGVAGG----SLLLI 350
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
7-378 4.76e-63

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 206.99  E-value: 4.76e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   7 LPMKLLLGVIAGIAVGQFAGVALMNVVVTVRYILGQLILFCVPLIIiGFIAPSITRLGN--NASKMLGVAVTIAYISSIG 84
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAAWLKPLGDLFIRLLKMIIVPLIF-ASIISGIASLGDgkKLGKLGGKTLLYFLVTTAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  85 AALFSMAAGYIMIPNLSIVTNVEGLQALPDL-------VFKLDIPPIM-------SVMSALALSMCLGLAAAW--TKAKS 148
Cdd:pfam00375  80 AALIGLLVANVFQPGSGLALIAASLKEAKAAeapslldFILNIIPSNIfealaegNVLAVIVFAILFGIALAAlgEKGEP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 149 ITNALEEFQLIVLAIVTKIVIpLLPFFIAFTFCSLSYEgSITKQLPVFIQVILIVMAGHYIWMALLYGLAG-IYTGKNPF 227
Cdd:pfam00375 160 LLNFIESLQEVMMKVIGWVMK-LAPIGVFALIANTVGT-YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIkFLGKVNPF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 228 DIIKNYGPAYITAVGTMSSAATLAVALRCAKKsEPPLRDDMVDFGIPLFANIHLCGSVLTEVFFVMTISKILYGAIpPIE 307
Cdd:pfam00375 238 KFLKKMLPALLTAFSTASSAATLPVTLECAEK-NLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDL-SFG 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537726000 308 TMVLFCLLLGIFAIAAPGVPGGTVMAsLGLITGILGFDDSGTALMLTIFALQDSFGTACNVTGDGALTLML 378
Cdd:pfam00375 316 QQLTLVLTATLASIGAAGVPGGGLVA-LGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIV 385
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
6-377 9.47e-24

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 101.73  E-value: 9.47e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   6 SLPMKLLLGVIAGIAVGQFAGVALMNVVVTVRYILGQLILFCVPLIIIGFIAPSITRLGNNAS--KMLGVAVTIAYISSI 83
Cdd:COG1301     4 SLTLQILIALVLGILLGLLLPELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKlgRIGGKTLLYFLVTTT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  84 GAALFSMAAGYIMIP------NLSIVTNVEGLQALPDLVFKLDIPPiMSVMSALA---------LSMCLGLAAA--WTKA 146
Cdd:COG1301    84 IALVIGLVVANLFQPgaglnlDLADAAAAEAAEAPSLLDFLLNIIP-SNIFEAFAegnmlqiifFAILFGIALAalGEKG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 147 KSITNALEEFQLIVLAIVtKIVIPLLPF--FIAFTFCSLSYEGSITKQLPVFIQVILIVMAGHyiWMALLYGLAGIYTGK 224
Cdd:COG1301   163 KPLLDFFESLSEVMFKIV-GWVMKLAPIgvFALIAATVAKYGLDALGSLGKLVLTVYLALLLH--LFVVLPLILRLLTGL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 225 NPFDIIKNYGPAYITAVGTMSSAATLAVALRCAKKsEPPLRDDMVDFGIPLFANIHLCGSVLTEVFFVMTISKiLYGAIP 304
Cdd:COG1301   240 SPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEE-KLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQ-AYGIDL 317

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537726000 305 PIETMVLFCLLLGIFAIAAPGVPGGTvMASLGLITGILGFDDSGTALMLTIFALQDSFGTACNVTGDGALTLM 377
Cdd:COG1301   318 SLGQQLTIVLTAVLASIGAAGVPGAG-LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVV 389
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 5-338 5.56e-05

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 44.85  E-value: 5.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000   5 TSLPMKLLLGVIAGIAVGQFAGVALMNVVvtvryILGQLI---LFCV-PLIIIGFIAPSITRLGNNASKMLGVAVTIAYI 80
Cdd:PRK13628   14 GSLVKQILIGLVLGILLALLSPPAAEAVG-----LLGTLFvgaLKAVaPILVFVLVMASIANHKKGQKTNIRPILVLYLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000  81 SSIGAALFSMAAGYIMIPNLSIVTNVEGLQA-------LPDLVFKLDIPPIMSVMSA-----LALSMCLGLA--AAWTKA 146
Cdd:PRK13628   89 GTFLAALVAVVASFLFPSTLVLVASAADISPpqgivevLKTLLLSLVDNPINALLNAnyigiLAWAIGLGLAlrHASDTT 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 147 KSITNALEEfqlIVLAIVtKIVIPLLPFFIaFTFCSLSYEGSITKQLPVFIQvILIVMAGHYIWMALLYG--LAGIYTGK 224
Cdd:PRK13628  169 KNVVNDLSE---AVSQIV-KWVIRFAPIGI-FGLVASTLAETGFSALAGYAQ-LLAVLVGCMLFVALVVNplIVFWKIRR 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537726000 225 NP----FDIIKNYGpayITAVGTMSSAATLAVALRCAKKSEppLRDDMVDFGIPLFANIHLCGSVLTevFFVMTISKILY 300
Cdd:PRK13628  243 NPyplvFTCLRESG---VTAFFTRSSAANIPVNMALCEKLG--LDEDTYSVSIPLGATINMAGAAIT--ITVLTLAAVHT 315

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 2537726000 301 GAIPP-IETMVLFCLLLGIFAIAAPGVPGGtvmaSLGLI 338
Cdd:PRK13628  316 LGIPVdLPTALLLSVVAAISACGASGVAGG----SLLLI 350
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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