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Conserved domains on  [gi|2563006601|ref|WP_305863222|]
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MULTISPECIES: RHS repeat-associated core domain-containing protein, partial [Bacteroides]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rhs_assc_core super family cl37315
RHS repeat-associated core domain; This model represents a conserved unique core sequence ...
 8-54 1.23e-13

RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.


The actual alignment was detected with superfamily member TIGR03696:

Pssm-ID: 274730 [Multi-domain]  Cd Length: 77  Bit Score: 64.83  E-value: 1.23e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2563006601   8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNG 54
Cdd:TIGR03696  31 LYYNGARYYDPELGRFLSPDPIGLG-GGLNLYAYVGNNPVNWVDPLG 76
RhsA super family cl34567
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 8-126 1.43e-08

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


The actual alignment was detected with superfamily member COG3209:

Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 55.92  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563006601    8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNGKEWGIVLNANGTKTVTLAVNFNVDSSLNLTSSQ 87
Cdd:COG3209    979 LYYNGARYYDPALGRFLSPDPIGLA-GGLNLYAYVGNNPVNYVDPLGLAALLGTTGLGGGAGVGAGAAGGGAAAAGGSAG 1057

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 2563006601   88 INAYKTAISTQLNNTFQEASGGMVSTAVTFYSGNENISQ 126
Cdd:COG3209   1058 AGAAGGGAGGAGAGGAGGGAGAGAGAAAGAAGGAGGGAG 1096
 
Name Accession Description Interval E-value
Rhs_assc_core TIGR03696
RHS repeat-associated core domain; This model represents a conserved unique core sequence ...
 8-54 1.23e-13

RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.


Pssm-ID: 274730 [Multi-domain]  Cd Length: 77  Bit Score: 64.83  E-value: 1.23e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2563006601   8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNG 54
Cdd:TIGR03696  31 LYYNGARYYDPELGRFLSPDPIGLG-GGLNLYAYVGNNPVNWVDPLG 76
RhsA COG3209
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 8-126 1.43e-08

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 55.92  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563006601    8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNGKEWGIVLNANGTKTVTLAVNFNVDSSLNLTSSQ 87
Cdd:COG3209    979 LYYNGARYYDPALGRFLSPDPIGLA-GGLNLYAYVGNNPVNYVDPLGLAALLGTTGLGGGAGVGAGAAGGGAAAAGGSAG 1057

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 2563006601   88 INAYKTAISTQLNNTFQEASGGMVSTAVTFYSGNENISQ 126
Cdd:COG3209   1058 AGAAGGGAGGAGAGGAGGGAGAGAGAAAGAAGGAGGGAG 1096
 
Name Accession Description Interval E-value
Rhs_assc_core TIGR03696
RHS repeat-associated core domain; This model represents a conserved unique core sequence ...
 8-54 1.23e-13

RHS repeat-associated core domain; This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.


Pssm-ID: 274730 [Multi-domain]  Cd Length: 77  Bit Score: 64.83  E-value: 1.23e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2563006601   8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNG 54
Cdd:TIGR03696  31 LYYNGARYYDPELGRFLSPDPIGLG-GGLNLYAYVGNNPVNWVDPLG 76
RhsA COG3209
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ...
 8-126 1.43e-08

Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];


Pssm-ID: 442442 [Multi-domain]  Cd Length: 1103  Bit Score: 55.92  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563006601    8 WYDYGARHYDAALGRWHVVDPLAEKyYSISPYAYCGNNPIMLVDVNGKEWGIVLNANGTKTVTLAVNFNVDSSLNLTSSQ 87
Cdd:COG3209    979 LYYNGARYYDPALGRFLSPDPIGLA-GGLNLYAYVGNNPVNYVDPLGLAALLGTTGLGGGAGVGAGAAGGGAAAAGGSAG 1057

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 2563006601   88 INAYKTAISTQLNNTFQEASGGMVSTAVTFYSGNENISQ 126
Cdd:COG3209   1058 AGAAGGGAGGAGAGGAGGGAGAGAGAAAGAAGGAGGGAG 1096
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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