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Conserved domains on  [gi|2568734418|ref|WP_306660011|]
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MULTISPECIES: phosphoribosyltransferase [Nostocaceae]

Protein Classification

phosphoribosyltransferase( domain architecture ID 10004949)

phosphoribosyltransferase catalyzes the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG1926 COG1926
Predicted phosphoribosyltransferase [General function prediction only];
10-123 3.23e-50

Predicted phosphoribosyltransferase [General function prediction only];


:

Pssm-ID: 441529  Cd Length: 209  Bit Score: 158.31  E-value: 3.23e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734418  10 RFRNRAEAGQQLANKLTDYAHRpDVLVLGLVRGGVPVAFEVATALNVSWDICLVRKLTVPGHKELAMGSIASSGVRCLNY 89
Cdd:COG1926     1 MFRDRTDAGRQLAERLAAYRGE-DPVVLALPRGGVPVAAEVARALGAPLDVLVVRKIGAPGNPELAIGAVAEDGVVVLNE 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2568734418  90 EVVSWLGISGKTIDDVAAREQRELERCDRDYRGH 123
Cdd:COG1926    80 DLIRRLGISEEYIEAEKAREREELERRRRRYRGG 113
 
Name Accession Description Interval E-value
COG1926 COG1926
Predicted phosphoribosyltransferase [General function prediction only];
10-123 3.23e-50

Predicted phosphoribosyltransferase [General function prediction only];


Pssm-ID: 441529  Cd Length: 209  Bit Score: 158.31  E-value: 3.23e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734418  10 RFRNRAEAGQQLANKLTDYAHRpDVLVLGLVRGGVPVAFEVATALNVSWDICLVRKLTVPGHKELAMGSIASSGVRCLNY 89
Cdd:COG1926     1 MFRDRTDAGRQLAERLAAYRGE-DPVVLALPRGGVPVAAEVARALGAPLDVLVVRKIGAPGNPELAIGAVAEDGVVVLNE 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2568734418  90 EVVSWLGISGKTIDDVAAREQRELERCDRDYRGH 123
Cdd:COG1926    80 DLIRRLGISEEYIEAEKAREREELERRRRRYRGG 113
pyrE PRK00455
orotate phosphoribosyltransferase; Validated
 14-65 2.02e-03

orotate phosphoribosyltransferase; Validated


Pssm-ID: 234771  Cd Length: 202  Bit Score: 36.29  E-value: 2.02e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2568734418  14 RAEAGQQLANKLTDYAHRPDVLVlGLVRGGVPVAFEVATALNVSWdiCLVRK 65
Cdd:PRK00455   47 LALLGRFLAEAIKDSGIEFDVVA-GPATGGIPLAAAVARALDLPA--IFVRK 95
 
Name Accession Description Interval E-value
COG1926 COG1926
Predicted phosphoribosyltransferase [General function prediction only];
10-123 3.23e-50

Predicted phosphoribosyltransferase [General function prediction only];


Pssm-ID: 441529  Cd Length: 209  Bit Score: 158.31  E-value: 3.23e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734418  10 RFRNRAEAGQQLANKLTDYAHRpDVLVLGLVRGGVPVAFEVATALNVSWDICLVRKLTVPGHKELAMGSIASSGVRCLNY 89
Cdd:COG1926     1 MFRDRTDAGRQLAERLAAYRGE-DPVVLALPRGGVPVAAEVARALGAPLDVLVVRKIGAPGNPELAIGAVAEDGVVVLNE 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2568734418  90 EVVSWLGISGKTIDDVAAREQRELERCDRDYRGH 123
Cdd:COG1926    80 DLIRRLGISEEYIEAEKAREREELERRRRRYRGG 113
PyrE COG0461
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ...
 14-65 6.69e-04

Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440229  Cd Length: 201  Bit Score: 37.44  E-value: 6.69e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2568734418  14 RAEAGQQLANKLTDYAHRPDVLVlGLVRGGVPVAFEVATALNVswDICLVRK 65
Cdd:COG0461    46 LELLGEALAELIKELGPEFDAVA-GPATGGIPLAAAVARALGL--PAIFVRK 94
pyrE PRK00455
orotate phosphoribosyltransferase; Validated
 14-65 2.02e-03

orotate phosphoribosyltransferase; Validated


Pssm-ID: 234771  Cd Length: 202  Bit Score: 36.29  E-value: 2.02e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2568734418  14 RAEAGQQLANKLTDYAHRPDVLVlGLVRGGVPVAFEVATALNVSWdiCLVRK 65
Cdd:PRK00455   47 LALLGRFLAEAIKDSGIEFDVVA-GPATGGIPLAAAVARALDLPA--IFVRK 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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