|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
237-505 |
5.94e-91 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 282.07 E-value: 5.94e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDLLNlirsyqdyytqppdiiqvqineidlefiQGDFIKILNSIE 316
Cdd:COG4191 137 EKLAALGELAAGIAHEINNPLAAILGNAELLRRRLEDEPD----------------------------PEELREALERIL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 YGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLtaidKHPEILLIKEYAS-LPLVECYPGLLNQVFMNI 395
Cdd:COG4191 189 EGAERAAEIVRSLRAFSRRDEEEREPVDLNELIDEALELLRPRL----KARGIEVELDLPPdLPPVLGDPGQLEQVLLNL 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 396 LVNAIDALHEynwqrtddeikNSPSRIQICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPLGKGTGIGLSISY 475
Cdd:COG4191 265 LINAIDAMEE-----------GEGGRITISTRR-EGDYVVISVRDNGPGIPPEVLERIFEPFFTTKPVGKGTGLGLSISY 332
|
250 260 270
....*....|....*....|....*....|
gi 2568734434 476 QiIVEKHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:COG4191 333 G-IVEKHGGRIEVESEPGGGTTFTITLPLA 361
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
237-510 |
1.06e-59 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 200.84 E-value: 1.06e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDllnliRSYQDYYtqppDIIqvqINEIDlefiqgdfikilnsie 316
Cdd:COG3852 130 EKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPD-----DELREYT----QLI---IEEAD---------------- 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLtaidkHPEILLIKEYA-SLPLVECYPGLLNQVFMNI 395
Cdd:COG3852 182 ----RLNNLVDRLLSFSRPRPPEREPVNLHEVLERVLELLRAEA-----PKNIRIVRDYDpSLPEVLGDPDQLIQVLLNL 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 396 LVNAIDALHEynwqrtddeiknsPSRIQICT---------HQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKG 466
Cdd:COG3852 253 VRNAAEAMPE-------------GGTITIRTrverqvtlgGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKE--KG 317
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2568734434 467 TGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPITQNSST 510
Cdd:COG3852 318 TGLGLAIVQKIV-EQHGGTIEVESEPGKGTTFRIYLPLEQAEEE 360
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
180-504 |
2.89e-58 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 202.87 E-value: 2.89e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 180 LKNYLTTSKMAQITLRDLNYELEMRVEKRAKeLRYKNDQLTQTLQKLQQTQLQLIQTEKMSSLGEMVAGIAHEINNPITF 259
Cdd:NF038348 266 LRQYELTTETLQRTRVHMEREIEERKAAQAR-LEQEKDEQRRLIHELEETHVQLLQSEKLASIGQLAAGVAHEINNPIGF 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 260 VKNNVSYVKEYSQDLLNLIrSYQDYYTQPPDI-----IQVQINEIDLEFIQGDFIKILNSIEYGTDRVEKIVKSLRNFSR 334
Cdd:NF038348 345 VSANLNTLKGWVHSLLDVI-AAQEAATPAHAAqtrapLAAAGRDADLDYVRGDIMTLIDESIDGAMRVRRIVQDLRDFSR 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 335 LDEAEIKSVDIHEGIDSTLMILSHRLTAidkhpEILLIKEYASLPLVECYPGLLNQVFMNILVNAIDALheynwqrtdde 414
Cdd:NF038348 424 PSGDEWSFADLHAGLESTLNVVHNELKY-----KADVVREYGDLPLVECNAAQLNQVFMNLLVNAAQAI----------- 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 415 iknsPSR--IQICTHQMNESwIQIRIIDNGIGIPENIRDKLFNPFFTTKPLGKGTGIGLSISYQiIVEKHTGKLYCNSTE 492
Cdd:NF038348 488 ----PGRgtITIRTTCDGDH-ASIAISDTGKGIPPDVMGRIFDPFFTTKPVGQGTGLGLSISHG-IVEHHRGRIDVASEP 561
|
330
....*....|..
gi 2568734434 493 EQGTEFVIEIPI 504
Cdd:NF038348 562 GRGSTFTITLPV 573
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
237-508 |
7.68e-57 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 195.18 E-value: 7.68e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDllnlirsyqdyytqppdiiqvqineiDLEFIQGDFIKILNSIE 316
Cdd:COG5000 196 ERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLAD--------------------------KLEEDREDLERALDTII 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 YGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLtaidKHPEILLIKEYA-SLPLVECYPGLLNQVFMNI 395
Cdd:COG5000 250 RQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYEPAL----KEKDIRLELDLDpDLPEVLADRDQLEQVLINL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 396 LVNAIDALHEynwqrtddeiknsPSRIQICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTGIGLSISY 475
Cdd:COG5000 326 LKNAIEAIEE-------------GGEIEVSTRR-EDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKP--KGTGLGLAIVK 389
|
250 260 270
....*....|....*....|....*....|...
gi 2568734434 476 QIIvEKHTGKLYCNSTEEQGTEFVIEIPITQNS 508
Cdd:COG5000 390 KIV-EEHGGTIELESRPGGGTTFTIRLPLAEEA 421
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
136-505 |
5.98e-40 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 147.36 E-value: 5.98e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 136 INQAIAILIDERVLKYKIYLLWSIGGSVTSLAFLIPSWLLVLRLLKNYLTTSKMAQITLRDLNYELEMRVEKRAKELRYK 215
Cdd:COG0642 5 LLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 216 nDQLTQTLQKLQQTQLQLIQTEKMSSLGEMVAGIAHEINNPITFVKNnvsyvkeYSQDLLNlirsyqdyyTQPPDIIQvq 295
Cdd:COG0642 85 -LLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRG-------YLELLLE---------ELDEEQRE-- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 296 ineidlefiqgdfikILNSIEYGTDRVEKIVKSLRNFSRLD----EAEIKSVDIHEGIDSTlmILSHRLTAIDKHPEILL 371
Cdd:COG0642 146 ---------------YLETILRSADRLLRLINDLLDLSRLEagklELEPEPVDLAELLEEV--VELFRPLAEEKGIELEL 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 372 IKEyASLPLVECYPGLLNQVFMNILVNAIDALHEynwqrtddeiknsPSRIQICTHQmNESWIQIRIIDNGIGIPENIRD 451
Cdd:COG0642 209 DLP-DDLPTVRGDPDRLRQVLLNLLSNAIKYTPE-------------GGTVTVSVRR-EGDRVRISVEDTGPGIPPEDLE 273
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2568734434 452 KLFNPFFTTKP--LGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:COG0642 274 RIFEPFFRTDPsrRGGGTGLGLAIVKR-IVELHGGTIEVESEPGKGTTFTVTLPLA 328
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
237-504 |
8.57e-40 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 147.62 E-value: 8.57e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDLLnlirsYQDYYtqppDIIqvqINEIDlefiqgdfikilnsie 316
Cdd:COG5807 142 EKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQESREDSE-----REEYF----NII---ISEID---------------- 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRltAIDKHPEILLIKEYaSLPLVECYPGLLNQVFMNIL 396
Cdd:COG5807 194 ----RINTIITELLVLSKPKKFNFKKLNLNDVLEDVIALLSTE--AILKNISIKYDLAD-DEPVINGDKNQLKQVFINLI 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIDALheynwqrtddEIKNspsRIQICThQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKplGKGTGIGLSISYQ 476
Cdd:COG5807 267 KNAIEAM----------ETGG---NITIKT-YVEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTK--EEGTGLGLSICKK 330
|
250 260
....*....|....*....|....*...
gi 2568734434 477 IIvEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:COG5807 331 II-EEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
237-513 |
2.09e-36 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 140.88 E-value: 2.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEysqdllNLIRSYQDYYtqppDIIqvqINEIDlefiqgdfikilnsie 316
Cdd:COG5809 265 EKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKD------TIDEEQKTYL----DIM---LSELD---------------- 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRltAIDKHPEILLIKEyASLPLVECYPGLLNQVFMNIL 396
Cdd:COG5809 316 ----RIESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPLLQPQ--ALLKNVQIELELE-DDIPDILGDENQLKQVFINLL 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIDALheynwqrtddeikNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTGIGLSISYQ 476
Cdd:COG5809 389 KNAIEAM-------------PEGGNITIETKAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKE--KGTGLGLMVSYK 453
|
250 260 270
....*....|....*....|....*....|....*..
gi 2568734434 477 IIVEkHTGKLYCNSTEEQGTEFVIEIPITQNSSTFTN 513
Cdd:COG5809 454 IIEE-HGGKITVESEVGKGTTFSITLPIKLSEQVSMN 489
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
244-507 |
8.53e-35 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 130.41 E-value: 8.53e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 244 EMVAGIAHEINNPITFVKNNVSYVKEYSQDLLNLIRSYqdyytqppdiiqvqineidlefiqgdfikiLNSIEYGTDRVE 323
Cdd:COG2205 18 EFLANVSHELRTPLTSILGAAELLLDEEDLSPEERREL------------------------------LEIIRESAERLL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 324 KIVKSLRNFSRLDEAEIK----SVDIHEGIDSTLMILSHRLTAIDKHpeiLLIKEYASLPLVECYPGLLNQVFMNILVNA 399
Cdd:COG2205 68 RLIEDLLDLSRLESGKLSlelePVDLAELLEEAVEELRPLAEEKGIR---LELDLPPELPLVYADPELLEQVLANLLDNA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 400 IdalheynwqrtddeiKNSP--SRIQICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPLGK--GTGIGLSISY 475
Cdd:COG2205 145 I---------------KYSPpgGTITISARR-EGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGegGTGLGLAIVK 208
|
250 260 270
....*....|....*....|....*....|..
gi 2568734434 476 QiIVEKHTGKLYCNSTEEQGTEFVIEIPITQN 507
Cdd:COG2205 209 R-IVEAHGGTIWVESEPGGGTTFTVTLPLAES 239
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
237-504 |
1.12e-34 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 137.41 E-value: 1.12e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDllnliRSYQDYytqppdiIQVQINEIDlefiqgdfikilnsie 316
Cdd:PRK11360 385 ERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSD-----PPSQEY-------LSVVLREVD---------------- 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHrltaIDKHPEILLIKEYAS-LPLVECYPGLLNQVFMNI 395
Cdd:PRK11360 437 ----RLNKVIDQLLEFSRPRESQWQPVSLNALVEEVLQLFQT----AGVQARVDFETELDNeLPPIWADPELLKQVLLNI 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 396 LVNAIDALheynwqrtddeikNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTGIGLSISY 475
Cdd:PRK11360 509 LINAVQAI-------------SARGKIRIRTWQYSDGQVAVSIEDNGCGIDPELLKKIFDPFFTTKA--KGTGLGLALSQ 573
|
250 260
....*....|....*....|....*....
gi 2568734434 476 QIIvEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK11360 574 RII-NAHGGDIEVESEPGVGTTFTLYLPI 601
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
237-505 |
7.04e-34 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 134.09 E-value: 7.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVsyvkeysQDLLNLIRSYQDYYtqppdiiQVQINEIDlefiqgdfikilnsie 316
Cdd:COG5805 282 EKLSIAGQLAAGIAHEIRNPLTSIKGFL-------QLLQPGIEDKEEYF-------DIMLSELD---------------- 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLTAIDKHPEILLIKEyasLPLVECYPGLLNQVFMNIL 396
Cdd:COG5805 332 ----RIESIISEFLALAKPQAVNKEKENINELIQDVVTLLETEAILHNIQIRLELLDE---DPFIYCDENQIKQVFINLI 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIDALheynwqrtddeikNSPSRIQICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTGIGLSISYQ 476
Cdd:COG5805 405 KNAIEAM-------------PNGGTITIHTEE-EDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKE--KGTGLGLMVSYK 468
|
250 260
....*....|....*....|....*....
gi 2568734434 477 IIvEKHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:COG5805 469 II-ENHNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
312-507 |
4.07e-31 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 126.05 E-value: 4.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 312 LNSIEYGTDRVEKIVKSLRNFSRLD--EAEIKSVDIHEGIDSTLMILSHRLTaiDKHPEIllikEYASLPLVECYPGLLN 389
Cdd:COG4251 323 LERIRDAAERMQALIDDLLAYSRVGrqELEFEPVDLNELLEEVLEDLEPRIE--ERGAEI----EVGPLPTVRGDPTLLR 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 390 QVFMNILVNAIdalhEYNwqrtddeIKNSPSRIQIcTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFT--TKPLGKGT 467
Cdd:COG4251 397 QVFQNLISNAI----KYS-------RPGEPPRIEI-GAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRlhSRDEYEGT 464
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2568734434 468 GIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPITQN 507
Cdd:COG4251 465 GIGLAIVKK-IVERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
109-507 |
2.64e-30 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 121.97 E-value: 2.64e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 109 QALAARSLLLSSQYESEKRKYASGVNKINQAIAILIDERVLKYKIYLLWSIGGSVTSLAFLIPSWLLVLRLLKNYLTTSK 188
Cdd:COG5002 34 LLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLIL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 189 MAQITLRDLNYELEMRVEKRAKELRYKNDQLTQTLQKLQQTQLQLIQTEKMSSlgEMVAGIAHEINNPITFVKNNVsyvk 268
Cdd:COG5002 114 LAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRR--EFVANVSHELRTPLTSIRGYL---- 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 269 eysqDLLnlirsyQDYYTQPPDIIQvqineidlefiqgdfiKILNSIEYGTDRVEKIVKSLRNFSRLDEAEIK----SVD 344
Cdd:COG5002 188 ----ELL------LDGAADDPEERR----------------EYLEIILEEAERLSRLVNDLLDLSRLESGELKlekePVD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 345 IHEGIDSTLMILSHRltAIDKHPEILLIKEyASLPLVECYPGLLNQVFMNILVNAIdalheynwqrtddeiKNSP--SRI 422
Cdd:COG5002 242 LAELLEEVVEELRPL--AEEKGIELELDLP-EDPLLVLGDPDRLEQVLTNLLDNAI---------------KYTPegGTI 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 423 QICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKP----LGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEF 498
Cdd:COG5002 304 TVSLRE-EDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKsrsrETGGTGLGLAIVKH-IVEAHGGRIWVESEPGKGTTF 381
|
....*....
gi 2568734434 499 VIEIPITQN 507
Cdd:COG5002 382 TITLPLARE 390
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
237-506 |
2.55e-28 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 117.16 E-value: 2.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDLLNlirsyQDYYtqppDIIQVQINeiDLEFIQGDFIkILNSIE 316
Cdd:COG5808 236 QKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELED-----QKYF----DIIQEEIQ--RINQIVSEFL-VLGKPT 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdrvekIVKSLRNfsrldeaeiksvDIHEGIDSTLMILSHRltaIDKHPEILLIKEYASLPLVECYPGLLNQVFMNIL 396
Cdd:COG5808 304 --------AKKLELD------------DLNELIEEILSIIDSE---ANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLI 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIDALHEynwqrtDDEIknspsriqICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKplGKGTGIGLSISYQ 476
Cdd:COG5808 361 KNAIEAMKE------GGKL--------TISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTK--EGGTGLGLSVCKR 424
|
250 260 270
....*....|....*....|....*....|
gi 2568734434 477 IIvEKHTGKLYCNSTEEQGTEFVIEIPITQ 506
Cdd:COG5808 425 IV-EMHGGEIDIESEEGKGTTFTIRLPLKK 453
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-504 |
2.76e-28 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 108.28 E-value: 2.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 385 PGLLNQVFMNILVNAIDALHEYnwqrtddeiknspSRIQICTHQMNES-WIQIRiiDNGIGIPENIRDKLFNPFFTTKPL 463
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGR-------------GRITIRTWAHVDQvLIEVE--DTGSGIDPEILGRIFDPFFTTKPV 65
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2568734434 464 GKGTGIGLSISYQIIVeKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:cd16943 66 GEGTGLGLSLSYRIIQ-KHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
385-505 |
9.23e-28 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.96 E-value: 9.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 385 PGLLNQVFMNILVNAIDALHEynwqrtddeiknsPSRIQICTHQMNEsWIQIRIIDNGIGIPENIRDKLFNPFFTTKP-- 462
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTPE-------------GGRITVTLERDGD-HVEITVEDNGPGIPPEDLEKIFEPFFRTDKrs 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2568734434 463 -LGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:smart00387 69 rKIGGTGLGLSIVKK-LVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
388-502 |
7.75e-25 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 98.44 E-value: 7.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHEynwqrtddeiknsPSRIQICTHQMNEsWIQIRIIDNGIGIPENIRDKLFNPFFTTKP--LGK 465
Cdd:cd00075 1 LEQVLSNLLDNALKYSPP-------------GGTIEISLRQEGD-GVVLEVEDNGPGIPEEDLERIFERFYRGDKsrEGG 66
|
90 100 110
....*....|....*....|....*....|....*..
gi 2568734434 466 GTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEI 502
Cdd:cd00075 67 GTGLGLAIVRR-IVEAHGGRITVESEPGGGTTFTVTL 102
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-502 |
4.18e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 96.37 E-value: 4.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHEYnwqrtddeiknSPSRIQICTHQMNESWIqIRIIDNGIGIPENIRDKLFNPFFTTKPLGKGT 467
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKV-----------ENPRIRIAARRLGGRLV-LVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGT 68
|
90 100 110
....*....|....*....|....*....|....*
gi 2568734434 468 GIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEI 502
Cdd:cd16976 69 GLGLSISYG-IVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
388-506 |
3.09e-23 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 94.36 E-value: 3.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHEynwqrtddeiknsPSRIQICTHQmnESWIQIRIIDNGIGIPENIRDKLFNPFFTT-KPLGKG 466
Cdd:pfam02518 6 LRQVLSNLLDNALKHAAK-------------AGEITVTLSE--GGELTLTVEDNGIGIPPEDLPRIFEPFSTAdKRGGGG 70
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2568734434 467 TGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPITQ 506
Cdd:pfam02518 71 TGLGLSIVRK-LVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
237-503 |
9.66e-23 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 102.07 E-value: 9.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPitfvknnvsyvkeysqdlLNLIRSYqdYYTQPPDIIQVQINEidlefiqgdFIKILNSIE 316
Cdd:COG4192 428 AKMAVVGQTMTSLAHELNQP------------------LNAMSMY--LFSAKKALEQENYAQ---------LPTSLDKIE 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 YGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRltaiDKHPEILLIkeYASLPLVECYPGLLNQVFMNIL 396
Cdd:COG4192 479 GLIERMDKIIKSLRQFSRKSDTPLQPVDLRQVIEQAWELVESR----AKPQQITLH--IPDDLMVQGDQVLLEQVLVNLL 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIDALHEynwqrtddeiknsPSRIQIcTHQMNESWIQIRIIDNGIGIPenIRDKLFNPFFTTKPLgkGTGIGLSISyQ 476
Cdd:COG4192 553 VNALDAVAT-------------QPQISV-DLLSNAENLRVAISDNGNGWP--LVDKLFTPFTTTKEV--GLGLGLSIC-R 613
|
250 260
....*....|....*....|....*..
gi 2568734434 477 IIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:COG4192 614 SIMQQFGGDLYLASTLERGAMVILEFN 640
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
237-504 |
1.79e-20 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 94.08 E-value: 1.79e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDllnlirsyqdyYTQPPDIIQVQINEIDlefiqgdfikilnsie 316
Cdd:PRK10364 232 EKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPA-----------GGEAHQLAQVMAKEAD---------------- 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtdRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSH---------RLTAIDkhpeillikeyaSLPLVECYPGL 387
Cdd:PRK10364 285 ----RLNRVVSELLELVKPTHLALQAVDLNDLINHSLQLVSQdansreiqlRFTAND------------TLPEIQADPDR 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHE-----YNWQRTDDEIKnspsriqicthqmneswiqIRIIDNGIGIPENIRDKLFNPFFTTKp 462
Cdd:PRK10364 349 LTQVLLNLYLNAIQAIGQhgvisVTASESGAGVK-------------------ISVTDSGKGIAADQLEAIFTPYFTTK- 408
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2568734434 463 lGKGTGIGLSIsYQIIVEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK10364 409 -AEGTGLGLAV-VHNIVEQHGGTIQVASQEGKGATFTLWLPV 448
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
2.23e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 85.91 E-value: 2.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHEYNWQRTDDEIKNSPSriqicthqmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGT 467
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGCERRELTIRTSPA---------DDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKS--EGL 69
|
90 100 110
....*....|....*....|....*....|....*.
gi 2568734434 468 GIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16920 70 GMGLSIC-RSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
237-503 |
2.97e-20 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 93.01 E-value: 2.97e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVSYVKEYSqdllnLIRSYQDYYtqppdiIQVQINEIdlefiqgdfikilnsie 316
Cdd:COG5806 196 EKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPE-----LSDEKRKQY------IRIALEEL----------------- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 ygtDRVEKIVKSLRNFSRLDeaeiksVDIHEGIDstlmiLSHRLTAIdkhpeILLIKEYASLPLVE----CYPGL----- 387
Cdd:COG5806 248 ---DRAEAIITDYLTFAKPQ------PEKLEKID-----VSEELEHV-----IDVLSPYANMNNVEiqteLEPGLyiegd 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 ---LNQVFMNILVNAIDAlheynwqrtddeIKNSpSRIQI-CTHQMNEswIQIRIIDNGIGI-PENIRdKLFNPFFTTKp 462
Cdd:COG5806 309 rqkLQQCLINIIKNGIEA------------MPNG-GTLTIdVSIDKNK--VIISIKDTGVGMtKEQLE-RLGEPYFSTK- 371
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2568734434 463 lGKGTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:COG5806 372 -EKGTGLGTMVSYRII-EAMNGTIRVESEVGKGTTFTITLP 410
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
388-503 |
4.74e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 85.51 E-value: 4.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHE--------YNWQRTDDEIKNSPSRIQicthqmnESWIQIRIIDNGIGIPENIRDKLFNPFFT 459
Cdd:cd16919 1 LELAILNLAVNARDAMPEggrltietSNQRVDADYALNYRDLIP-------GNYVCLEVSDTGSGMPAEVLRRAFEPFFT 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2568734434 460 TKPLGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16919 74 TKEVGKGTGLGLSMVYG-FVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
237-505 |
6.35e-19 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 90.51 E-value: 6.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNPITFVKNNVsyvkEYSQDLLNLIRSYQDYytqppdiiqvqineidlefiqgdfikiLNSIE 316
Cdd:PRK13837 445 RRLEAVGTLASGIAHNFNNILGAILGYA----EMALNKLARHSRAARY---------------------------IDEII 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 317 YGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLTaidkhPEILLIKEYASLPL-VECYPGLLNQVFMNI 395
Cdd:PRK13837 494 SAGARARLIIDQILAFGRKGERNTKPFDLSELVTEIAPLLRVSLP-----PGVELDFDQDQEPAvVEGNPAELQQVLMNL 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 396 LVNAIDALheynwqRTDDEIKNSPSRIQICTHQ-------MNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTG 468
Cdd:PRK13837 569 CSNAAQAM------DGAGRVDISLSRAKLRAPKvlshgvlPPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRA--GGTG 640
|
250 260 270
....*....|....*....|....*....|....*..
gi 2568734434 469 IGLSISYQIIVEkHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:PRK13837 641 LGLATVHGIVSA-HAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
362-504 |
2.86e-18 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 86.83 E-value: 2.86e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 362 AIDKHPEiLLIKEYASLPLVECYPGLLNQVFMNILVNAIDALheynwqrtdDEIKNSPSRIQICTHQMNEsWIQIRIIDN 441
Cdd:COG3290 257 ARERGID-LTIDIDSDLPDLPLSDTDLVTILGNLLDNAIEAV---------EKLPEEERRVELSIRDDGD-ELVIEVEDS 325
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2568734434 442 GIGIPENIRDKLFNPFFTTKpLGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:COG3290 326 GPGIPEELLEKIFERGFSTK-LGEGRGLGLALVKQ-IVEKYGGTIEVESEEGEGTVFTVRLPK 386
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
359-504 |
5.59e-18 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 85.13 E-value: 5.59e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 359 RLTAIDKHPEILLIKEY-ASLPLVECYPGLLNQVFMNILVNAIDALHEynwqrTDDEIK-NSPSRIQICTH-QMNESWIQ 435
Cdd:PRK11073 208 QLVSLELPDNVRLIRDYdPSLPELAHDPDQIEQVLLNIVRNALQALGP-----EGGTITlRTRTAFQLTLHgERYRLAAR 282
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2568734434 436 IRIIDNGIGIPENIRDKLFNPFFTTKPlgKGTGIGLSISyQIIVEKHTGKLYCNSTEEQgTEFVIEIPI 504
Cdd:PRK11073 283 IDIEDNGPGIPPHLQDTLFYPMVSGRE--GGTGLGLSIA-RNLIDQHSGKIEFTSWPGH-TEFSVYLPI 347
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
388-503 |
1.98e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 77.92 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIdalheynwQRTDD-EIKnspSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFF-----TTK 461
Cdd:cd16922 1 LRQILLNLLGNAI--------KFTEEgEVT---LRVSLEEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSqadssTTR 69
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2568734434 462 PLGkGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16922 70 KYG-GTGLGLAISKK-LVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
1.04e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 75.90 E-value: 1.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALheynwQRTDDEI--KNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgK 465
Cdd:cd16918 1 LIQVFLNLVRNAAQAL-----AGSGGEIilRTRTQRQVTLGHPRHRLALRVSVIDNGPGIPPDLQDTIFYPMVSGRE--N 73
|
90 100 110
....*....|....*....|....*....|....*...
gi 2568734434 466 GTGIGLSISyQIIVEKHTGKLYCNSTEEQgTEFVIEIP 503
Cdd:cd16918 74 GTGLGLAIA-QNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
237-507 |
4.28e-16 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 80.87 E-value: 4.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 237 EKMSSLGEMVAGIAHEINNpitfvknnvsyvkeysqdLLNLIRSYQDyytqppdIIQVQINE--IDLEFIQgdfiKILNS 314
Cdd:PRK13557 158 QKMEALGQLTGGIAHDFNN------------------LLQVMSGYLD-------VIQAALSHpdADRGRMA----RSVEN 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 315 IEYGTDRVEKIVKSLRNFSRLDEAEIKSVDIHEGIDSTLMILSHRLTaidkhPEILLIKEYAslplvecyPGLLN----- 389
Cdd:PRK13557 209 IRAAAERAATLTQQLLAFARKQRLEGRVLNLNGLVSGMGELAERTLG-----DAVTIETDLA--------PDLWNcridp 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 390 ---QV-FMNILVNAIDALHEYN--WQRTDDEIKNSPSRIQIctHQMNES-WIQIRIIDNGIGIPENIRDKLFNPFFTTKP 462
Cdd:PRK13557 276 tqaEVaLLNVLINARDAMPEGGrvTIRTRNVEIEDEDLAMY--HGLPPGrYVSIAVTDTGSGMPPEILARVMDPFFTTKE 353
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2568734434 463 LGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPITQN 507
Cdd:PRK13557 354 EGKGTGLGLSMVYG-FAKQSGGAVRIYSEVGEGTTVRLYFPASDQ 397
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
336-504 |
6.00e-16 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 80.33 E-value: 6.00e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 336 DEAEIKSVDIHEGIDSTLMILSHRLTA----IDKHPEillikeyASLPLVECYPGLLNQVFMNILVNAIDALHEYNWQRT 411
Cdd:TIGR02938 339 PQEIVVPVNLNQILRDVITLSTPRLLAagivVDWQPA-------ATLPAILGRELQLRSLFKALVDNAIEAMNIKGWKRR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 412 DDEIknspsriqicTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTK-PLGKGTGIGLSISYQiIVEKHTGKLYCNS 490
Cdd:TIGR02938 412 ELSI----------TTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFTTKgGSRKHIGMGLSVAQE-IVADHGGIIDLDD 480
|
170
....*....|....
gi 2568734434 491 TEEQGTEFVIEIPI 504
Cdd:TIGR02938 481 DYSEGCRIIVEFRV 494
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-503 |
1.09e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 72.96 E-value: 1.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 387 LLNQVFMNILVNAIDALHEynwqRTDDEIKnspSRIQICTHQmnESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlgKG 466
Cdd:cd16944 4 QISQVLTNILKNAAEAIEG----RPSDVGE---VRIRVEADQ--DGRIVLIVCDNGKGFPREMRHRATEPYVTTRP--KG 72
|
90 100 110
....*....|....*....|....*....|....*..
gi 2568734434 467 TGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16944 73 TGLGLAIVKKIM-EEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
394-503 |
2.19e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 68.85 E-value: 2.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 394 NILVNAIDALheynwQRTDDEiknsPSRIQICTHQMNeSWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlGKGTGIGLSI 473
Cdd:cd16915 7 NLIDNALDAL-----AATGAP----NKQVEVFLRDEG-DDLVIEVRDTGPGIAPELRDKVFERGVSTKG-QGERGIGLAL 75
|
90 100 110
....*....|....*....|....*....|
gi 2568734434 474 SYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16915 76 VRQ-SVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
3.27e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 65.81 E-value: 3.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIdalheyNWQRTDDeiknsPSRIQICTHQMNESWiQIRIIDNGIGIPENIRDKLFNPF--FTTKPLGK 465
Cdd:cd16921 1 LGQVLTNLLGNAI------KFRRPRR-----PPRIEVGAEDVGEEW-TFYVRDNGIGIDPEYAEKVFGIFqrLHSREEYE 68
|
90 100 110
....*....|....*....|....*....|....*...
gi 2568734434 466 GTGIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16921 69 GTGVGLAIV-RKIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
1.34e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 58.11 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIdalheynwqrtddeiKNSPSRIQICTHQMNESWIqIRIIDNGIGIPENIRDKLFNPFFTTKPL---- 463
Cdd:cd16949 1 LARALENVLRNAL---------------RYSPSKILLDISQDGDQWT-ITITDDGPGVPEDQLEQIFLPFYRVDSArdre 64
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2568734434 464 GKGTGIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16949 65 SGGTGLGLAIA-ERAIEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
335-503 |
1.18e-09 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 60.82 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 335 LDEAEIKSVDIH---------EGIDSTLMILShrlTAIDKHPEILLIKeyASLPLVECYPGLLNQVFMNILVNAIDALHE 405
Cdd:PRK10490 722 LDMARIQSGGFNlrkewltleEVVGSALQMLE---PGLSGHPINLSLP--EPLTLIHVDGPLFERVLINLLENAVKYAGA 796
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 406 ynwqrtddeiknsPSRIQICTHQMNEsWIQIRIIDNGIGIPENIRDKLFNPFF-----TTKPlgkGTGIGLSISyQIIVE 480
Cdd:PRK10490 797 -------------QAEIGIDAHVEGE-RLQLDVWDNGPGIPPGQEQLIFDKFArgnkeSAIP---GVGLGLAIC-RAIVE 858
|
170 180
....*....|....*....|...
gi 2568734434 481 KHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:PRK10490 859 VHGGTIWAENRPEGGACFRVTLP 881
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
1.21e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 55.66 E-value: 1.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDAlheynwqrtddeikNSPSRIQICTHQMNES-WIQIRIIDNGIGIPENIRDKLFNPFFTTKP---- 462
Cdd:cd16953 1 LGQVLRNLIGNAISF--------------SPPDTGRITVSAMPTGkMVTISVEDEGPGIPQEKLESIFDRFYTERPanea 66
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2568734434 463 LGKGTGIGLSISYQIIvEKHTGKLYCNSTEE----QGTEFVIEIP 503
Cdd:cd16953 67 FGQHSGLGLSISRQII-EAHGGISVAENHNQpgqvIGARFTVQLP 110
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
378-506 |
4.71e-09 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 58.04 E-value: 4.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 378 LPLVECYPGLLNQVFMNILVNAIdalheynwqrtddeiKNSPS--RIQICT-HQMNEsWIQIRIIDNGIGIPENIRDKLF 454
Cdd:PRK09303 263 LPSVYADQERIRQVLLNLLDNAI---------------KYTPEggTITLSMlHRTTQ-KVQVSICDTGPGIPEEEQERIF 326
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2568734434 455 -NPFFTTKPLGK-GTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPITQ 506
Cdd:PRK09303 327 eDRVRLPRDEGTeGYGIGLSVCRRIV-RVHYGQIWVDSEPGQGSCFHFTLPVYR 379
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
394-503 |
1.08e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 57.62 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 394 NILVNAIDALheynwqrtddeIKNSPSRIQICTHQMNEsWIQIRIIDNGIGIPENIRDKLFNPFFTTKplGKGTGIGLSI 473
Cdd:PRK11086 440 NLIENALEAV-----------GGEEGGEISVSLHYRNG-WLHCEVSDDGPGIAPDEIDAIFDKGYSTK--GSNRGVGLYL 505
|
90 100 110
....*....|....*....|....*....|
gi 2568734434 474 SYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:PRK11086 506 VKQ-SVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
412-497 |
1.87e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 52.41 E-value: 1.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 412 DDEIKNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPL-GKGTGIGLSIsYQIIVEKHTGKLYCNS 490
Cdd:cd16940 23 DNAVRYSPQGSRVEIKLSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQnYGGSGLGLSI-VKRIVELHGGQIFLGN 101
|
....*..
gi 2568734434 491 TEEQGTE 497
Cdd:cd16940 102 AQGGGLE 108
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
391-503 |
1.93e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 52.29 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 391 VFMNILVNAIdalhEYNWQRTDDEIKNspsriqicthQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTK---PLGKGT 467
Cdd:cd16948 9 IIGQIVSNAL----KYSKQGGKIEIYS----------ETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrNFQEST 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 2568734434 468 GIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16948 75 GMGLYLVKKLC-DKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
6.15e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 50.51 E-value: 6.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIDALHeynwqrtddeiknspSRIQIcTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKP----L 463
Cdd:cd16939 1 MARALDNLLRNALRYAH---------------RTVRI-ALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPsrdrA 64
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2568734434 464 GKGTGIGLSIsYQIIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16939 65 TGGFGLGLAI-VHRVALWHGGHVECDDSELGGACFRLTWP 103
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
387-502 |
1.00e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 50.15 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 387 LLNQVFMNILVNAIDAlheynwqrtddeiknSPSRIQICTHQMNES-WIQIRIIDNGIGIPENIRDKLFNPFFTTKPL-- 463
Cdd:cd16975 4 LLSRALINIISNACQY---------------APEGGTVSISIYDEEeYLYFEIWDNGHGFSEQDLKKALELFYRDDTSrr 68
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2568734434 464 -GKGTGIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEI 502
Cdd:cd16975 69 sGGHYGMGLYIA-KNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
381-504 |
1.31e-07 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 54.08 E-value: 1.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 381 VECYPGLLNQVFMNILVNAIDAlheynwqrtddeiknSP--SRIQICTHQMNESwIQIRIIDNGIGIPENIRDKLFNPFF 458
Cdd:PRK11100 362 VLGDPFLLRQALGNLLDNAIDF---------------SPegGTITLSAEVDGEQ-VALSVEDQGPGIPDYALPRIFERFY 425
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2568734434 459 TT-KPLG--KGTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK11100 426 SLpRPANgrKSTGLGLAFVREVA-RLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
349-504 |
3.11e-07 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 53.37 E-value: 3.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 349 IDSTLMILSHRLtaidKHPEILLIKEYA-SLP-LVECYPGLLNQVFMNILVNAIdalheynwqRTDDEiknspSRIQICT 426
Cdd:PRK11466 525 LESTLQLMSGRV----KGRPIRLATDIAdDLPtALMGDPRRIRQVITNLLSNAL---------RFTDE-----GSIVLRS 586
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2568734434 427 HQMNESWIqIRIIDNGIGIPENIRDKLFNPFFTTKPLGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK11466 587 RTDGEQWL-VEVEDSGCGIDPAKLAEIFQPFVQVSGKRGGTGLGLTISSR-LAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-486 |
1.02e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 47.46 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 385 PGLLNQVFMNILVNAIDALHEYnwqrtddeiknspSRIQICTHqMNESWIQIRIIDNGIGIPENIRDKLFNPFFT-TKPL 463
Cdd:cd16945 2 PFLLRQAINNLLDNAIDFSPEG-------------GLIALQLE-ADTEGIELLVFDEGSGIPDYALNRVFERFYSlPRPH 67
|
90 100
....*....|....*....|....*
gi 2568734434 464 G--KGTGIGLSISYQIIvEKHTGKL 486
Cdd:cd16945 68 SgqKSTGLGLAFVQEVA-QLHGGRI 91
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
428-503 |
1.29e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 46.67 E-value: 1.29e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2568734434 428 QMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPL--GKGTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16950 25 DGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNArgTSGTGLGLAIVQRIS-DAHGGSLTLANRAGGGLCARIELP 101
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
420-506 |
1.32e-06 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 50.68 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 420 SRIQICTHqMNESWIQIRIIDNGIGIPENIRDKLFNPFFT--TKPLGKGTGIGLSIsYQIIVEKHTGKLYCNSTEEQGTE 497
Cdd:PRK09467 349 GWIKVSSG-TEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRgdSARGSSGTGLGLAI-VKRIVDQHNGKVELGNSEEGGLS 426
|
....*....
gi 2568734434 498 FVIEIPITQ 506
Cdd:PRK09467 427 ARAWLPLTT 435
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
414-507 |
3.29e-06 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 49.63 E-value: 3.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 414 EIKNSPSRIQICTHQMNEsWIQIRIIDNGIGIPENIRDKLFNPFFTTkplGKGTGIGLSISYQIIvEKHTGKLYC---NS 490
Cdd:COG2972 354 EPKEGGGTIRISIRKEGD-RLVITVEDNGVGMPEEKLEKLLEELSSK---GEGRGIGLRNVRERL-KLYYGEEYGleiES 428
|
90
....*....|....*..
gi 2568734434 491 TEEQGTEFVIEIPITQN 507
Cdd:COG2972 429 EPGEGTTVTIRIPLEEE 445
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
385-504 |
5.86e-06 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 48.86 E-value: 5.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 385 PGLLNQVFMNILVNAIdalhEYnwqrTDdeiknSPSRIQICTHQMNESWIqIRIIDNGIGIPENIRDKLFNPFFTTKP-- 462
Cdd:PRK10549 350 PDRLMQLFNNLLENSL----RY----TD-----SGGSLHISAEQRDKTLR-LTFADSAPGVSDEQLQKLFERFYRTEGsr 415
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2568734434 463 --LGKGTGIGLSISYQIiVEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK10549 416 nrASGGSGLGLAICLNI-VEAHNGRIIAAHSPFGGVSITVELPL 458
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
434-503 |
8.12e-06 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 48.78 E-value: 8.12e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2568734434 434 IQIRIIDNGIGIPENIRDKLFNPFFTTKPL--GK---GTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:PRK11091 431 LTFEVEDSGIGIPEDELDKIFAMYYQVKDShgGKpatGTGIGLAVSKR-LAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
332-504 |
8.67e-06 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 48.69 E-value: 8.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 332 FSRLdEAEiKSV------DIHEGIDSTLMILSHrlTAIDKHPEI-LLIKeyASLP-LVECYPGLLNQVFMNILVNAIdal 403
Cdd:PRK11107 351 FSKL-EAG-KLVlenipfSLRETLDEVVTLLAH--SAHEKGLELtLNID--PDVPdNVIGDPLRLQQIITNLVGNAI--- 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 404 heynwQRTddEIKNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPF-----FTTKPLGkGTGIGLSISyQII 478
Cdd:PRK11107 422 -----KFT--ESGNIDILVELRALSNTKVQLEVQIRDTGIGISERQQSQLFQAFrqadaSISRRHG-GTGLGLVIT-QKL 492
|
170 180
....*....|....*....|....*.
gi 2568734434 479 VEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK11107 493 VNEMGGDISFHSQPNRGSTFWFHLPL 518
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
436-505 |
1.35e-05 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 48.10 E-value: 1.35e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 436 IRIIDNGIGIPENIRDKLFNPFFTTKPLGKGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPIT 505
Cdd:PRK15347 547 FTVEDTGCGIDIQQQQQIFTPFYQADTHSQGTGLGLTIASS-LAKMMGGELTLFSTPGVGSCFSLVLPLN 615
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
390-503 |
3.06e-05 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 43.25 E-value: 3.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 390 QVFMNILVNAIdalheynwqrtddeiKNSPS--RIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPLG--- 464
Cdd:cd16925 7 RVVLNLLSNAF---------------KFTPDggRIRCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSStra 71
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2568734434 465 -KGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16925 72 hGGTGLGLSIVKE-FVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
3.40e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 42.84 E-value: 3.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIdalheynwQRTDdeiknSPSRIQICTHQMNESWiQIRIIDNGIGIPENIRDKLFNPFFT-----TKP 462
Cdd:cd16946 5 LQQLFVNLLENSL--------RYTD-----TGGKLRIRAAQTPQEV-RLDVEDSAPGVSDDQLARLFERFYRvessrNRA 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2568734434 463 LGkGTGIGLSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16946 71 SG-GSGLGLAICHN-IALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
383-506 |
7.14e-05 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 45.31 E-value: 7.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 383 CYPGLLNQVFMNILVNAIdalheynwqrtddeiKNSPSRIQIcTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTT-- 460
Cdd:PRK09470 349 GNPNALASALENIVRNAL---------------RYSHTKIEV-AFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVde 412
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2568734434 461 ---KPLGkGTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPITQ 506
Cdd:PRK09470 413 ardRESG-GTGLGLAIVENAI-QQHRGWVKAEDSPLGGLRLTIWLPLYK 459
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
385-502 |
1.36e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 41.85 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 385 PGLLNQVFMNILVNAidalheYNWqrtddeiknSPSRIQICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPLG 464
Cdd:cd16954 35 RNDLMELLGNLLDNA------CKW---------CLEFVEVTARQ-TDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQR 98
|
90 100 110
....*....|....*....|....*....|....*...
gi 2568734434 465 KGTGIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEI 502
Cdd:cd16954 99 PGQGLGLAIA-KEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
388-504 |
4.01e-04 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 43.04 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAIdalheynwqrtddeiKNSPSRIQICTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKPlGK-- 465
Cdd:PRK10841 563 LQQVISNLLSNAI---------------KFTDTGCIVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGT-GVqr 626
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2568734434 466 ---GTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK10841 627 nfqGTGLGLAICEKLI-NMMDGDISVDSEPGMGSQFTIRIPL 667
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
395-503 |
4.09e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 39.72 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 395 ILV-NAIDalHEYNWQRTDDEIKnspsriqICTHQmNESWIQIRIIDNGIGIPENIRDKLFNPFFTTKplgKGTGIGL-S 472
Cdd:cd16957 8 VLVeNAIR--HAFPKRKENNEVR-------VVVKK-DQHKVHVSVSDNGQGIPEERLDLLGKTTVTSE---KGTGTALeN 74
|
90 100 110
....*....|....*....|....*....|..
gi 2568734434 473 ISYQII-VEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16957 75 LNRRLIgLFGSEACLHIESEVHGGTEVWFVIP 106
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
380-504 |
9.63e-04 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 42.03 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 380 LVECYPGLLNQVFMNILVNAIDAlheynwqRTDDEIKNSPSRIQIcthQMNESWIQIRIIDNGIGIPENIRDKLFNPFFT 459
Cdd:PRK09959 821 LVKIDPQAFKQVLSNLLSNALKF-------TTEGAVKITTSLGHI---DDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQ 890
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2568734434 460 TKPlGK---GTGIGLSISYQIIvEKHTGKLYCNSTEEQGTEFVIEIPI 504
Cdd:PRK09959 891 TSA-GRqqtGSGLGLMICKELI-KNMQGDLSLESHPGIGTTFTITIPV 936
|
|
| HATPase_PDK-like |
cd16929 |
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain ... |
383-503 |
1.45e-03 |
|
Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of all four PDK isoforms (pyruvate dehydrogenase kinases 1-4) that have been described in mammals, and other PDKs including Saccharomyces Pkp1p and Pkp2p. PDKs and phosphatases tightly regulate the mitochondrial pyruvate dehydrogenase complex (PDC) by reversible phosphorylation. PDC catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, connecting glycolysis and the TCA acid cycle. Also included in this family is mammalian branched-chain alpha-ketoacid dehydrogenase kinase (BDK), a mitochondrial protein kinase that phosphorylates a subunit of the branched-chain a-ketoacid dehydrogenase (BCKD) complex, which catalyzes the oxidative decarboxylation of branched-chain alpha-ketoacids derived from leucine, isoleucine, and valine, a rate-limiting step in the oxidative degradation of these branched-chain amino acids.
Pssm-ID: 340406 [Multi-domain] Cd Length: 169 Bit Score: 39.63 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 383 CYPGLLNQVFMNILVNAIDALHEYNWQRTDDEiknSPSRIQICthqMNESWIQIRIIDNGIGIPENIRDKLFNPFFTTK- 461
Cdd:cd16929 39 YVPSHLYYILFELLKNAMRATVESHGDDSDDL---PPIKVTVA---KGDEDLTIKISDRGGGIPREDLARLFSYMYSTAp 112
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 2568734434 462 -----------------PLGkGTGIGLSISyQIIVEKHTGKLYCNSTEEQGTEFVIEIP 503
Cdd:cd16929 113 qpslddfsdlisgtqpsPLA-GFGYGLPMS-RLYAEYFGGDLDLQSMEGYGTDVYIYLK 169
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
241-337 |
1.47e-03 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 37.19 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 241 SLGEMVAGIAHEINNPITFVKNNVSYVKEYSQDllnlirsyqdyytqppdiiqvqineidlefiqGDFIKILNSIEYGTD 320
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLD--------------------------------EEQREYLETILRSAE 48
|
90
....*....|....*..
gi 2568734434 321 RVEKIVKSLRNFSRLDE 337
Cdd:pfam00512 49 RLLRLINDLLDLSRIEA 65
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
239-279 |
1.59e-03 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 36.81 E-value: 1.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2568734434 239 MSSLGEMVAGIAHEINNPITFVKNNVSYVKEYS------QDLLNLIR 279
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELlddeeqREYLERIR 47
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
320-512 |
2.33e-03 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 40.36 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 320 DRVEKIVKSLRNFSRLDEAEiksVDIH-EGIDSTLMiLSHRLTAIDK-HPEILLIKEYASLPLVECY-PGLLNQVFMNIL 396
Cdd:PRK10604 253 GQLEALIEELLTYARLDRPQ---NELHlSEPDLPAW-LSTHLADIQAvTPEKTVRLDTPHQGDYGALdMRLMERVLDNLL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 397 VNAIdalheynwqrtddeiKNSPSRIQI-CTHQMNESWIQIRiiDNGIGIPENIRDKLFNPFFTTKP-----LGkGTGIG 470
Cdd:PRK10604 329 NNAL---------------RYAHSRVRVsLLLDGNQACLIVE--DDGPGIPPEERERVFEPFVRLDPsrdraTG-GCGLG 390
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2568734434 471 LSISYQiIVEKHTGKLYCNSTEEQGTEFVIEIPITQNSSTFT 512
Cdd:PRK10604 391 LAIVHS-IALAMGGSVNCDESELGGARFSFSWPVWHNLPQFT 431
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
388-503 |
3.16e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 37.37 E-value: 3.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 388 LNQVFMNILVNAidalheynwqrtddeIKNSP--SRIQIcTHQMNESWIQIRIIDNGIGIPENIRDKLFNPFF---TTKP 462
Cdd:cd16923 1 LQRVFSNLLSNA---------------IKYSPenTRIYI-TSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdNSRN 64
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2568734434 463 LGkGTGIGLSISyQIIVEKHTGKLYCNStEEQGTEFVIEIP 503
Cdd:cd16923 65 TE-GAGLGLSIA-KAIIELHGGSASAEY-DDNHDLFKVRLP 102
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
435-510 |
3.92e-03 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 39.57 E-value: 3.92e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2568734434 435 QIRIIDNGIGIPENIRDKLFNPFFTTKPLGKGTGIGLSIsYQIIVEKHTGKLYC-NSTEEQGTEFVIEIPITQNSST 510
Cdd:PRK10755 281 VLAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSI-VSRITQLHHGQFFLqNRQERSGTRAWVWLPKAQNVAN 356
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
379-503 |
4.18e-03 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 39.76 E-value: 4.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 379 PLVECYPGLLNQVFMNILVNAIdalheynwqrtddeiKNSPSRIQICTH-QMNESWIQIRIIDNGIGIPENIRDKLFNPF 457
Cdd:PRK09835 367 CQVAGDPLMLRRAISNLLSNAL---------------RYTPAGEAITVRcQEVDHQVQLVVENPGTPIAPEHLPRLFDRF 431
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2568734434 458 FTTKPL----GKGTGIGLSIsYQIIVEKHTGKLYCNStEEQGTEFVIEIP 503
Cdd:PRK09835 432 YRVDPSrqrkGEGSGIGLAI-VKSIVVAHKGTVAVTS-DARGTRFVISLP 479
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
419-506 |
5.59e-03 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 38.45 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 419 PSRIQICTHQmNESWIQIRIIDNGIGIPENIRdklfnpffttkplgKGTGIGL-SIsyQIIVEKHTGKLYCNSTEEQGTE 497
Cdd:COG4585 180 ATRVTVTLEV-DDGELTLTVRDDGVGFDPEAA--------------PGGGLGLrGM--RERAEALGGTLTIGSAPGGGTR 242
|
....*....
gi 2568734434 498 FVIEIPITQ 506
Cdd:COG4585 243 VRATLPLAA 251
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
241-337 |
6.05e-03 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 35.23 E-value: 6.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2568734434 241 SLGEMVAGIAHEINNPITFVKNNVSyvkeysqdllnLIRsyqdyytqppdiiqvqinEIDLEFIQGDFIKIlnsIEYGTD 320
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLE-----------LLL------------------DTELSEEQREYLET---ILREAE 48
|
90
....*....|....*..
gi 2568734434 321 RVEKIVKSLRNFSRLDE 337
Cdd:smart00388 49 RLLRLINDLLDLSRIEA 65
|
|
| |
