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Conserved domains on  [gi|2707155928|ref|WP_338140992|]
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hypothetical protein [Candidatus Entotheonella palauensis]

Protein Classification

HNH endonuclease family protein( domain architecture ID 1640)

HNH endonuclease family protein, similar to Physarum polycephalum intron-encoded endonuclease I-Ppoi which mediates the mobility of intron 3 in the ribosomal DNA

EC:  3.1.-.-
Gene Ontology:  GO:0004519

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HNHc super family cl00083
HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic ...
 56-109 7.73e-04

HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.


The actual alignment was detected with superfamily member pfam01844:

Pssm-ID: 469607 [Multi-domain]  Cd Length: 47  Bit Score: 35.02  E-value: 7.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2707155928  56 CEYCGKQ---QGYFEVHHVRKLSDikDGKEAWQKLMIarrrktlvLCVECHDQLHAG 109
Cdd:pfam01844   1 CQYCGRPfhiSDALTVDHIIPLSD--GGADDIENLIL--------LCPSCHNKKHNR 47
 
Name Accession Description Interval E-value
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 56-109 7.73e-04

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 35.02  E-value: 7.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2707155928  56 CEYCGKQ---QGYFEVHHVRKLSDikDGKEAWQKLMIarrrktlvLCVECHDQLHAG 109
Cdd:pfam01844   1 CQYCGRPfhiSDALTVDHIIPLSD--GGADDIENLIL--------LCPSCHNKKHNR 47
HNHc smart00507
HNH nucleases;
53-104 8.20e-03

HNH nucleases;


Pssm-ID: 214702 [Multi-domain]  Cd Length: 52  Bit Score: 32.43  E-value: 8.20e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2707155928   53 AQQCEYCGKQ-QGYFEVHHVRKLSDikDGKEAWQKLMIarrrktlvLCVECHD 104
Cdd:smart00507  10 DGVCAYCGKPaSEGLEVDHIIPLSD--GGNDDLDNLVL--------LCPKCHI 52
 
Name Accession Description Interval E-value
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 56-109 7.73e-04

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 35.02  E-value: 7.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2707155928  56 CEYCGKQ---QGYFEVHHVRKLSDikDGKEAWQKLMIarrrktlvLCVECHDQLHAG 109
Cdd:pfam01844   1 CQYCGRPfhiSDALTVDHIIPLSD--GGADDIENLIL--------LCPSCHNKKHNR 47
HNHc smart00507
HNH nucleases;
53-104 8.20e-03

HNH nucleases;


Pssm-ID: 214702 [Multi-domain]  Cd Length: 52  Bit Score: 32.43  E-value: 8.20e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2707155928   53 AQQCEYCGKQ-QGYFEVHHVRKLSDikDGKEAWQKLMIarrrktlvLCVECHD 104
Cdd:smart00507  10 DGVCAYCGKPaSEGLEVDHIIPLSD--GGNDDLDNLVL--------LCPKCHI 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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