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Conserved domains on  [gi|2727942442|ref|WP_343217767|]
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type VI secretion system contractile sheath large subunit [Desulfatitalea alkaliphila]

Protein Classification

type VI secretion system contractile sheath large subunit( domain architecture ID 10007506)

type VI secretion system (T6SS) contractile sheath large subunit forms a long contractile organelle in V. cholerae and in E. coli, suggesting that sheath contraction powers the secretion

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG3517 COG3517
Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family ...
11-486 0e+00

Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442739 [Multi-domain]  Cd Length: 474  Bit Score: 855.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  11 ETSLLDDIVTATRLKPADEGYGVAKRGVEALLAQLVVPGRTVDKVSNALIDEFIAEIDGKLSRQLDAILHNPEVQRLESA 90
Cdd:COG3517     1 EGSLLDQILAQTRLPPSDEARDIAKAAVATLVAQVLEGTVTVSKDLKALIDAMIAEIDELLSEQLNEILHHPEFQKLESS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  91 WRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYTAEYGQFGGQPYGNIIANYEFGPGPQDIKLL 170
Cdd:COG3517    81 WRGLHYLVDNTETDENLKIRVLNVSKEELLKDFEKAPEFDQSGLFKKVYEEEYGTFGGEPYGALIGDYEFDHSPEDIALL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 171 QYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQSFRETEDARYVALTVPRFLLRLPYGQDTQP 250
Cdd:COG3517   161 RKMSKVAAAAHAPFIAAASPSLFGLDSFTELSNPRDLAKIFETPEYAKWRSFRESEDSRYVGLTLPRFLLRLPYGPDTNP 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 251 VKTFNYEENVSAT-HDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGGTVEDLPLHQFE-AMGAVQTKIPTEVLISE 328
Cdd:COG3517   241 VEGFNFEEDVDGAdHEKYLWGNAAYALATNLTRAFAKYGWCAAIRGVEGGGLVEGLPTHTFEtDDGGVDLKCPTEVAITD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 329 RREFELAEEGFIALTMRKGSDNACFFSANSVQKPKNFgiseEGKNAELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSW 408
Cdd:COG3517   321 RREKELSDLGFIPLVHRKNTDYAAFFSAQSLQKPKEY----DDPDATANARLSARLPYIFAVSRFAHYLKVMQRDKIGSF 396
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2727942442 409 KERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVEGEPGWYRVGMKVRPHFKYMGAFFTLSLVGKLDK 486
Cdd:COG3517   397 KEREDLERELNDWISQYVTGDDNASQETKARYPLREARVEVEEVPGKPGWYRAVLFLRPHFQLEGLTVSLRLVAELPK 474
 
Name Accession Description Interval E-value
COG3517 COG3517
Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family ...
11-486 0e+00

Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442739 [Multi-domain]  Cd Length: 474  Bit Score: 855.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  11 ETSLLDDIVTATRLKPADEGYGVAKRGVEALLAQLVVPGRTVDKVSNALIDEFIAEIDGKLSRQLDAILHNPEVQRLESA 90
Cdd:COG3517     1 EGSLLDQILAQTRLPPSDEARDIAKAAVATLVAQVLEGTVTVSKDLKALIDAMIAEIDELLSEQLNEILHHPEFQKLESS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  91 WRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYTAEYGQFGGQPYGNIIANYEFGPGPQDIKLL 170
Cdd:COG3517    81 WRGLHYLVDNTETDENLKIRVLNVSKEELLKDFEKAPEFDQSGLFKKVYEEEYGTFGGEPYGALIGDYEFDHSPEDIALL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 171 QYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQSFRETEDARYVALTVPRFLLRLPYGQDTQP 250
Cdd:COG3517   161 RKMSKVAAAAHAPFIAAASPSLFGLDSFTELSNPRDLAKIFETPEYAKWRSFRESEDSRYVGLTLPRFLLRLPYGPDTNP 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 251 VKTFNYEENVSAT-HDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGGTVEDLPLHQFE-AMGAVQTKIPTEVLISE 328
Cdd:COG3517   241 VEGFNFEEDVDGAdHEKYLWGNAAYALATNLTRAFAKYGWCAAIRGVEGGGLVEGLPTHTFEtDDGGVDLKCPTEVAITD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 329 RREFELAEEGFIALTMRKGSDNACFFSANSVQKPKNFgiseEGKNAELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSW 408
Cdd:COG3517   321 RREKELSDLGFIPLVHRKNTDYAAFFSAQSLQKPKEY----DDPDATANARLSARLPYIFAVSRFAHYLKVMQRDKIGSF 396
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2727942442 409 KERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVEGEPGWYRVGMKVRPHFKYMGAFFTLSLVGKLDK 486
Cdd:COG3517   397 KEREDLERELNDWISQYVTGDDNASQETKARYPLREARVEVEEVPGKPGWYRAVLFLRPHFQLEGLTVSLRLVAELPK 474
VI_chp_2 TIGR03355
type VI secretion protein, EvpB/VC_A0108 family; Work by Mougous, et al. (2006), describes ...
11-485 0e+00

type VI secretion protein, EvpB/VC_A0108 family; Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274538 [Multi-domain]  Cd Length: 473  Bit Score: 839.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  11 ETSLLDDIVTATRLKPADEGYGVAKRGVEALLAQLVVPGRTVDKVSNALIDEFIAEIDGKLSRQLDAILHNPEVQRLESA 90
Cdd:TIGR03355   1 ELSLLDSILEETRLAREEEAYDRAKDGVSAFLTEALKGTVVVERDLKATIDEMIAEIDRLISRQLDAILHAPEFQQLEST 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  91 WRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYTAEYGQFGGQPYGNIIANYEFGPGPQDIKLL 170
Cdd:TIGR03355  81 WRGLKYLVDRTETRENLKIRVLNVSKEDLLKDFEDAPEFDQSGLFKKVYEEEYGTFGGEPFGALIGDYEFSHSPQDVELL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 171 QYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQSFRETEDARYVALTVPRFLLRLPYGQDTQP 250
Cdd:TIGR03355 161 RNMSKVAAAAHAPFIAAAAPEFFGLDSFTELPNPRDLSKIFEGPEYAKWRSFRESEDSRYVGLTLPRFLLRLPYGPKTNP 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 251 VKTFNYEENVSAT-HDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGGTVEDLPLHQFEA-MGAVQTKIPTEVLISE 328
Cdd:TIGR03355 241 VEEFNYEEDVDGNdHDKYLWGNAAYAMAARITRSFAKYGWCTNIRGVESGGAVEDLPVHLFESdDGEVQLKCPTEVAISD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 329 RREFELAEEGFIALTMRKGSDNACFFSANSVQKPKNFGISEegknAELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSW 408
Cdd:TIGR03355 321 RREFELAELGFIPLVHRKNSDYAAFFSAQSVQKPKKYDNTE----ATANARLSARLPYIFAVSRFAHYLKVIQRDKIGSF 396
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2727942442 409 KERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVEGEPGWYRVGMKVRPHFKYMGAFFTLSLVGKLD 485
Cdd:TIGR03355 397 KERADLERELNNWINQYVSDNDDPSQEVKARRPLRAARVEVSEVPGNPGYYRAVLFLRPHFQLEGLTVSLRLVAKLP 473
VipB pfam05943
EvpB/VC_A0108, tail sheath N-terminal domain; EvpB is a family of Gram-negative probable type ...
61-360 0e+00

EvpB/VC_A0108, tail sheath N-terminal domain; EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell.


Pssm-ID: 428683  Cd Length: 301  Bit Score: 567.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  61 DEFIAEIDGKLSRQLDAILHNPEVQRLESAWRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYT 140
Cdd:pfam05943   1 DRLIAEIDALLSRQLNAILHHPEFQKLEASWRGLKYLVDNTETSENLKIRVLNVSKEELLKDLERAPEFDQSGLFKKVYE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 141 AEYGQFGGQPYGNIIANYEFGPGPQDIKLLQYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQ 220
Cdd:pfam05943  81 EEYGTFGGEPFGALIGDYEFSHSPDDIELLEGLSKVAAAAHAPFIAAASPSLFGLDSFTELSNPRDLAKIFEGPEYAKWR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 221 SFRETEDARYVALTVPRFLLRLPYGQDTQPVKTFNYEENVSATHDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGG 300
Cdd:pfam05943 161 SFRESEDSRYVGLTLPRVLLRLPYGPDTNPVEGFNFEEDVGGDHEDYLWGNAAYAFATNLTRAFAKYGWCAAIRGVEGGG 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2727942442 301 TVEDLPLHQFEA-MGAVQTKIPTEVLISERREFELAEEGFIALTMRKGSDNACFFSANSVQ 360
Cdd:pfam05943 241 LVEGLPVHTFETdDGGVALKCPTEVAITDRREAELSDLGFIPLVHRKNTDYAAFFSAQSLQ 301
 
Name Accession Description Interval E-value
COG3517 COG3517
Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family ...
11-486 0e+00

Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442739 [Multi-domain]  Cd Length: 474  Bit Score: 855.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  11 ETSLLDDIVTATRLKPADEGYGVAKRGVEALLAQLVVPGRTVDKVSNALIDEFIAEIDGKLSRQLDAILHNPEVQRLESA 90
Cdd:COG3517     1 EGSLLDQILAQTRLPPSDEARDIAKAAVATLVAQVLEGTVTVSKDLKALIDAMIAEIDELLSEQLNEILHHPEFQKLESS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  91 WRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYTAEYGQFGGQPYGNIIANYEFGPGPQDIKLL 170
Cdd:COG3517    81 WRGLHYLVDNTETDENLKIRVLNVSKEELLKDFEKAPEFDQSGLFKKVYEEEYGTFGGEPYGALIGDYEFDHSPEDIALL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 171 QYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQSFRETEDARYVALTVPRFLLRLPYGQDTQP 250
Cdd:COG3517   161 RKMSKVAAAAHAPFIAAASPSLFGLDSFTELSNPRDLAKIFETPEYAKWRSFRESEDSRYVGLTLPRFLLRLPYGPDTNP 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 251 VKTFNYEENVSAT-HDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGGTVEDLPLHQFE-AMGAVQTKIPTEVLISE 328
Cdd:COG3517   241 VEGFNFEEDVDGAdHEKYLWGNAAYALATNLTRAFAKYGWCAAIRGVEGGGLVEGLPTHTFEtDDGGVDLKCPTEVAITD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 329 RREFELAEEGFIALTMRKGSDNACFFSANSVQKPKNFgiseEGKNAELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSW 408
Cdd:COG3517   321 RREKELSDLGFIPLVHRKNTDYAAFFSAQSLQKPKEY----DDPDATANARLSARLPYIFAVSRFAHYLKVMQRDKIGSF 396
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2727942442 409 KERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVEGEPGWYRVGMKVRPHFKYMGAFFTLSLVGKLDK 486
Cdd:COG3517   397 KEREDLERELNDWISQYVTGDDNASQETKARYPLREARVEVEEVPGKPGWYRAVLFLRPHFQLEGLTVSLRLVAELPK 474
VI_chp_2 TIGR03355
type VI secretion protein, EvpB/VC_A0108 family; Work by Mougous, et al. (2006), describes ...
11-485 0e+00

type VI secretion protein, EvpB/VC_A0108 family; Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274538 [Multi-domain]  Cd Length: 473  Bit Score: 839.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  11 ETSLLDDIVTATRLKPADEGYGVAKRGVEALLAQLVVPGRTVDKVSNALIDEFIAEIDGKLSRQLDAILHNPEVQRLESA 90
Cdd:TIGR03355   1 ELSLLDSILEETRLAREEEAYDRAKDGVSAFLTEALKGTVVVERDLKATIDEMIAEIDRLISRQLDAILHAPEFQQLEST 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  91 WRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYTAEYGQFGGQPYGNIIANYEFGPGPQDIKLL 170
Cdd:TIGR03355  81 WRGLKYLVDRTETRENLKIRVLNVSKEDLLKDFEDAPEFDQSGLFKKVYEEEYGTFGGEPFGALIGDYEFSHSPQDVELL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 171 QYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQSFRETEDARYVALTVPRFLLRLPYGQDTQP 250
Cdd:TIGR03355 161 RNMSKVAAAAHAPFIAAAAPEFFGLDSFTELPNPRDLSKIFEGPEYAKWRSFRESEDSRYVGLTLPRFLLRLPYGPKTNP 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 251 VKTFNYEENVSAT-HDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGGTVEDLPLHQFEA-MGAVQTKIPTEVLISE 328
Cdd:TIGR03355 241 VEEFNYEEDVDGNdHDKYLWGNAAYAMAARITRSFAKYGWCTNIRGVESGGAVEDLPVHLFESdDGEVQLKCPTEVAISD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 329 RREFELAEEGFIALTMRKGSDNACFFSANSVQKPKNFGISEegknAELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSW 408
Cdd:TIGR03355 321 RREFELAELGFIPLVHRKNSDYAAFFSAQSVQKPKKYDNTE----ATANARLSARLPYIFAVSRFAHYLKVIQRDKIGSF 396
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2727942442 409 KERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVEGEPGWYRVGMKVRPHFKYMGAFFTLSLVGKLD 485
Cdd:TIGR03355 397 KERADLERELNNWINQYVSDNDDPSQEVKARRPLRAARVEVSEVPGNPGYYRAVLFLRPHFQLEGLTVSLRLVAKLP 473
VipB pfam05943
EvpB/VC_A0108, tail sheath N-terminal domain; EvpB is a family of Gram-negative probable type ...
61-360 0e+00

EvpB/VC_A0108, tail sheath N-terminal domain; EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell.


Pssm-ID: 428683  Cd Length: 301  Bit Score: 567.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442  61 DEFIAEIDGKLSRQLDAILHNPEVQRLESAWRSLKYLVDKTDFRENIRIEILNAGKQELLEDFEDAPEVSKAGLYKTVYT 140
Cdd:pfam05943   1 DRLIAEIDALLSRQLNAILHHPEFQKLEASWRGLKYLVDNTETSENLKIRVLNVSKEELLKDLERAPEFDQSGLFKKVYE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 141 AEYGQFGGQPYGNIIANYEFGPGPQDIKLLQYVAAVSAMAHAPFVAAAGPQFFGVDSFNELPNLKDLHAVFEGPQYTKWQ 220
Cdd:pfam05943  81 EEYGTFGGEPFGALIGDYEFSHSPDDIELLEGLSKVAAAAHAPFIAAASPSLFGLDSFTELSNPRDLAKIFEGPEYAKWR 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 221 SFRETEDARYVALTVPRFLLRLPYGQDTQPVKTFNYEENVSATHDHYLWGNAAFAFATRLTDSFAKYRWCTNIIGPMGGG 300
Cdd:pfam05943 161 SFRESEDSRYVGLTLPRVLLRLPYGPDTNPVEGFNFEEDVGGDHEDYLWGNAAYAFATNLTRAFAKYGWCAAIRGVEGGG 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2727942442 301 TVEDLPLHQFEA-MGAVQTKIPTEVLISERREFELAEEGFIALTMRKGSDNACFFSANSVQ 360
Cdd:pfam05943 241 LVEGLPVHTFETdDGGVALKCPTEVAITDRREAELSDLGFIPLVHRKNTDYAAFFSAQSLQ 301
VipB_2 pfam18945
EvpB/VC_A0108, tail sheath gpW/gp25-like domain; EvpB is a family of Gram-negative probable ...
374-484 3.65e-63

EvpB/VC_A0108, tail sheath gpW/gp25-like domain; EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell. This entry represents the gpW/gp25-like domain.


Pssm-ID: 436852 [Multi-domain]  Cd Length: 111  Bit Score: 200.41  E-value: 3.65e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2727942442 374 AELNYKLGTQLPYMYVANRLAHYLKVIQRENIGSWKERADLDRELNTWIRQYVADQENPPASVRSRRPLRQAQITVEDVE 453
Cdd:pfam18945   1 ATANARLSAQLPYIFAVSRFAHYLKVIQRDKIGSFKSAEDLERELNRWIRQYVTGNDNASPETKARYPLREARVEVSEVP 80
                          90       100       110
                  ....*....|....*....|....*....|.
gi 2727942442 454 GEPGWYRVGMKVRPHFKYMGAFFTLSLVGKL 484
Cdd:pfam18945  81 GKPGWYRAVLHLRPHFQLEGLTVSLRLVAEL 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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