NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2731651628|ref|WP_345734069|]
View 

substrate-binding domain-containing protein, partial [Cryptosporangium minutisporangium]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ChvE super family cl46169
sugar ABC transporter substrate-binding protein;
41-142 1.64e-42

sugar ABC transporter substrate-binding protein;


The actual alignment was detected with superfamily member NF040907:

Pssm-ID: 468842  Cd Length: 319  Bit Score: 142.69  E-value: 1.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAADI 120
Cdd:NF040907    1 VGIAMPTKSSERWIADGNNMVKQLEAAGYKTDLQYAEDDVPTQVSQIENMITKGAKVLVIAAIDGTALTDVLQQAADAGI 80

                          90       100
                  ....*....|....*....|..
gi 2731651628 121 AVIAYDRLIRDTADVDYYATFD 142
Cdd:NF040907   81 PVIAYDRLIRGSENVDYYATFD 102
 
Name Accession Description Interval E-value
ChvE NF040907
sugar ABC transporter substrate-binding protein;
41-142 1.64e-42

sugar ABC transporter substrate-binding protein;


Pssm-ID: 468842  Cd Length: 319  Bit Score: 142.69  E-value: 1.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAADI 120
Cdd:NF040907    1 VGIAMPTKSSERWIADGNNMVKQLEAAGYKTDLQYAEDDVPTQVSQIENMITKGAKVLVIAAIDGTALTDVLQQAADAGI 80

                          90       100
                  ....*....|....*....|..
gi 2731651628 121 AVIAYDRLIRDTADVDYYATFD 142
Cdd:NF040907   81 PVIAYDRLIRGSENVDYYATFD 102
XylF COG4213
ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism] ...
 37-142 1.77e-35

ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 443359 [Multi-domain]  Cd Length: 310  Bit Score: 124.09  E-value: 1.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  37 DRGRIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAA 116
Cdd:COG4213     1 GKIKIGVSLPTKTSERWIRDGDNFKAALKELGYEVDVQNANGDVATQLSQIENMITKGADVLVIAPIDGTALAAVLEKAK 80

                          90       100
                  ....*....|....*....|....*.
gi 2731651628 117 AADIAVIAYDRLIRDTaDVDYYATFD 142
Cdd:COG4213    81 AAGIPVIAYDRLILNS-DVDYYVSFD 105
PBP1_ChvE cd19994
periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling ...
 40-142 5.96e-35

periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system; Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380649 [Multi-domain]  Cd Length: 304  Bit Score: 122.74  E-value: 5.96e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:cd19994     1 KIGISLPTKSEERWIKDGENLKSELEEAGYTVDLQYADDDVATQNSQIENMINKGAKVLVIAPVDGSALGDVLEEAKDAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIRDTADVDYYATFD 142
Cdd:cd19994    81 IPVIAYDRLIMNTDAVDYYVTFD 103
Peripla_BP_4 pfam13407
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ...
 41-142 3.79e-09

Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins. This domain recognizes fructose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 433182 [Multi-domain]  Cd Length: 259  Bit Score: 53.08  E-value: 3.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQ-YADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:pfam13407   1 IGVVPKSTGNPFFQAAEEGAEEAAKELGGEVIVVgPAEADAAEQVAQIEDAIAQGVDAIIVAPVDPTALAPVLKKAKDAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIrDTADVDYYATFD 142
Cdd:pfam13407  81 IPVVTFDSDA-PSSPRLAYVGFD 102
xylF PRK10355
D-xylose ABC transporter substrate-binding protein;
32-142 2.68e-08

D-xylose ABC transporter substrate-binding protein;


Pssm-ID: 182403 [Multi-domain]  Cd Length: 330  Bit Score: 50.90  E-value: 2.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  32 QGAAADRGRIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDV 111
Cdd:PRK10355   19 VAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNV 98

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2731651628 112 LAKAAAADIAVIAYDRLIRDtADVDYYATFD 142
Cdd:PRK10355   99 IKEAKQEGIKVLAYDRMINN-ADIDFYISFD 128
 
Name Accession Description Interval E-value
ChvE NF040907
sugar ABC transporter substrate-binding protein;
41-142 1.64e-42

sugar ABC transporter substrate-binding protein;


Pssm-ID: 468842  Cd Length: 319  Bit Score: 142.69  E-value: 1.64e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAADI 120
Cdd:NF040907    1 VGIAMPTKSSERWIADGNNMVKQLEAAGYKTDLQYAEDDVPTQVSQIENMITKGAKVLVIAAIDGTALTDVLQQAADAGI 80

                          90       100
                  ....*....|....*....|..
gi 2731651628 121 AVIAYDRLIRDTADVDYYATFD 142
Cdd:NF040907   81 PVIAYDRLIRGSENVDYYATFD 102
XylF COG4213
ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism] ...
 37-142 1.77e-35

ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 443359 [Multi-domain]  Cd Length: 310  Bit Score: 124.09  E-value: 1.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  37 DRGRIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAA 116
Cdd:COG4213     1 GKIKIGVSLPTKTSERWIRDGDNFKAALKELGYEVDVQNANGDVATQLSQIENMITKGADVLVIAPIDGTALAAVLEKAK 80

                          90       100
                  ....*....|....*....|....*.
gi 2731651628 117 AADIAVIAYDRLIRDTaDVDYYATFD 142
Cdd:COG4213    81 AAGIPVIAYDRLILNS-DVDYYVSFD 105
PBP1_ChvE cd19994
periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling ...
 40-142 5.96e-35

periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system; Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380649 [Multi-domain]  Cd Length: 304  Bit Score: 122.74  E-value: 5.96e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:cd19994     1 KIGISLPTKSEERWIKDGENLKSELEEAGYTVDLQYADDDVATQNSQIENMINKGAKVLVIAPVDGSALGDVLEEAKDAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIRDTADVDYYATFD 142
Cdd:cd19994    81 IPVIAYDRLIMNTDAVDYYVTFD 103
PBP1_ABC_xylose_binding-like cd01538
periplasmic xylose-like sugar-binding component of the ABC-type transport systems that belong ...
 41-142 1.06e-23

periplasmic xylose-like sugar-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily; Periplasmic xylose-like sugar-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380480 [Multi-domain]  Cd Length: 283  Bit Score: 92.87  E-value: 1.06e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAADI 120
Cdd:cd01538     2 IGVSLPNLREARWQTDRDIMVEQLEEKGAKVLVQSADGDKAKQASQIENLLTQGADVLVLAPVDGQALSPVVAEAKAEGI 81

                          90       100
                  ....*....|....*....|..
gi 2731651628 121 AVIAYDRLIRDtADVDYYATFD 142
Cdd:cd01538    82 KVIAYDRLILN-ADVDYYISFD 102
PBP1_ABC_xylose_binding-like cd19992
periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic ...
 40-142 1.44e-19

periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380647 [Multi-domain]  Cd Length: 284  Bit Score: 81.86  E-value: 1.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:cd19992     1 KIGVSFPTQQEERWQKDKEYMEEEAKELGVELIFQVADNDAKTQASQVENLLAQGIDVLIIAPVDAGAAANIVDKAKAAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIRDtADVDYYATFD 142
Cdd:cd19992    81 VPVISYDRLILN-ADVDLYVGRD 102
PBP1_ABC_xylose_binding cd19991
D-xylose binding periplasmic protein; Periplasmic xylose-binding component of the ABC-type ...
 40-142 6.25e-19

D-xylose binding periplasmic protein; Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380646 [Multi-domain]  Cd Length: 284  Bit Score: 79.97  E-value: 6.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:cd19991     1 KIGFSMDSLRVERWQRDRDYFVKKAKELGAEVIVQSANGDDEKQISQAEELIEQGVDVLVVVPNNGEALAPIVKEAKKAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIRDtADVDYYATFD 142
Cdd:cd19991    81 VPVLAYDRLILN-ADVDLYVSFD 102
PBP1_ABC_xylose_binding-like cd19995
periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic ...
 41-142 6.97e-12

periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380650 [Multi-domain]  Cd Length: 294  Bit Score: 61.15  E-value: 6.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWI-LDGENLEYEFDRM--GYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAA 117
Cdd:cd19995     2 VAFLLPDTTSARWEqQDAPGFEKAMKKLcpDCKVIYQNANGDASTQQQQAEAAITQGAKVLVVDPVDSNAAAGIVAKAAQ 81

                          90       100
                  ....*....|....*....|....*
gi 2731651628 118 ADIAVIAYDRLIrDTADVDYYATFD 142
Cdd:cd19995    82 AGVPVIAYDRLI-LGGPADYYVSFD 105
RbsB COG1879
ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH ...
 5-112 1.32e-10

ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain [Carbohydrate transport and metabolism];


Pssm-ID: 441483 [Multi-domain]  Cd Length: 307  Bit Score: 57.63  E-value: 1.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628   5 RFVRLSVLVIALVTAAVGCSDAAEDSdQGAAADRGRIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQV 84
Cdd:COG1879     1 KRLALLAAVLALALALAACGSAAAEA-AAAAAKGKTIGFVVKTLGNPFFVAVRKGAEAAAKELGVELIVVDAEGDAAKQI 79

                          90       100
                  ....*....|....*....|....*...
gi 2731651628  85 SQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:COG1879    80 SQIEDLIAQGVDAIIVSPVDPDALAPAL 107
Peripla_BP_4 pfam13407
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ...
 41-142 3.79e-09

Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins. This domain recognizes fructose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 433182 [Multi-domain]  Cd Length: 259  Bit Score: 53.08  E-value: 3.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQ-YADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:pfam13407   1 IGVVPKSTGNPFFQAAEEGAEEAAKELGGEVIVVgPAEADAAEQVAQIEDAIAQGVDAIIVAPVDPTALAPVLKKAKDAG 80

                          90       100
                  ....*....|....*....|...
gi 2731651628 120 IAVIAYDRLIrDTADVDYYATFD 142
Cdd:pfam13407  81 IPVVTFDSDA-PSSPRLAYVGFD 102
xylF PRK10355
D-xylose ABC transporter substrate-binding protein;
32-142 2.68e-08

D-xylose ABC transporter substrate-binding protein;


Pssm-ID: 182403 [Multi-domain]  Cd Length: 330  Bit Score: 50.90  E-value: 2.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  32 QGAAADRGRIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDV 111
Cdd:PRK10355   19 VAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNV 98

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2731651628 112 LAKAAAADIAVIAYDRLIRDtADVDYYATFD 142
Cdd:PRK10355   99 IKEAKQEGIKVLAYDRMINN-ADIDFYISFD 128
PBP1_ABC_xylose_binding-like cd19993
periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic ...
 52-142 1.07e-07

periplasmic xylose-like sugar-binding component of the ABC-type transport systems; Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.


Pssm-ID: 380648 [Multi-domain]  Cd Length: 287  Bit Score: 49.40  E-value: 1.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  52 RWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAADIAVIAYDRLIrD 131
Cdd:cd19993    13 RWKTDEAAMKKALEKAGAKYISADAQSSAEKQLDDIESLISQGAKALIVLAQDGDAILPAVEKAAAEGIPVIAYDRLI-E 91

                          90
                  ....*....|.
gi 2731651628 132 TADVdYYATFD 142
Cdd:cd19993    92 NPIA-FYISFD 101
PBP1_ABC_sugar_binding-like cd01536
periplasmic sugar-binding domain of active transport systems that are members of the type 1 ...
 40-112 2.21e-07

periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily; Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.


Pssm-ID: 380478 [Multi-domain]  Cd Length: 268  Bit Score: 48.33  E-value: 2.21e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd01536     1 KIGVVVKDLTNPFWVAVKKGAEAAAKELGVELVVLDAQGDVAKQISQIEDLIAQGVDAIIIAPVDSEALVPAV 73
PBP1_ABC_sugar_binding-like cd19999
monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic ...
 74-112 3.25e-06

monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.


Pssm-ID: 380654 [Multi-domain]  Cd Length: 313  Bit Score: 44.99  E-value: 3.25e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2731651628  74 QYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd19999    40 QNADADATGQISQIRNMINEGVDAILIDPVSATALNPVI 78
PBP1_galactofuranose_YtfQ-like cd06309
periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems; ...
 40-141 6.51e-06

periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems; Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.


Pssm-ID: 380532 [Multi-domain]  Cd Length: 285  Bit Score: 44.13  E-value: 6.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVLAKAAAAD 119
Cdd:cd06309     1 TVGFSQAGSESPWRVANTKSIKEAAKKRGYELVYTDANQDQEKQINDIRDLIAQGVDAILISPIDATGWDPVLKEAKDAG 80

                          90       100
                  ....*....|....*....|..
gi 2731651628 120 IAVIAYDRLIrDTADVDYYATF 141
Cdd:cd06309    81 IPVILVDRTI-DGEDGSLYVTF 101
PBP1_ABC_sugar_binding-like cd19998
monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic ...
 76-112 2.76e-05

monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.


Pssm-ID: 380653 [Multi-domain]  Cd Length: 302  Bit Score: 42.28  E-value: 2.76e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2731651628  76 ADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd19998    41 SGTDVQAQISAIDNMIAAGYDAILIYAISPTALNPVI 77
PBP1_sensor_kinase-like cd06308
periplasmic binding domain of two-component sensor kinase signaling systems; Periplasmic ...
 76-112 3.71e-05

periplasmic binding domain of two-component sensor kinase signaling systems; Periplasmic binding domain of two-component sensor kinase signaling systems, some of which are fused with a C-terminal histidine kinase A domain (HisK) and/or a signal receiver domain (REC). Members of this group share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily and are predicted to be involved in sensing of environmental stimuli; their substrate specificities, however, are not known in detail.


Pssm-ID: 380531 [Multi-domain]  Cd Length: 268  Bit Score: 41.76  E-value: 3.71e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2731651628  76 ADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd06308    38 AQGDAAKQIADIEDLIAQGVDLLIVSPNEADALTPVV 74
PBP1_ABC_sugar_binding-like cd19996
monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic ...
 76-112 4.19e-05

monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.


Pssm-ID: 380651 [Multi-domain]  Cd Length: 302  Bit Score: 41.84  E-value: 4.19e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2731651628  76 ADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd19996    40 AQGDTQKQIADIQDLIAQGVDAIIVSPNSPTALLPAI 76
PBP1_ABC_sugar_binding-like cd06322
periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; This group ...
 41-107 4.96e-05

periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consist of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.


Pssm-ID: 380545 [Multi-domain]  Cd Length: 270  Bit Score: 41.49  E-value: 4.96e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATA 107
Cdd:cd06322     2 IGVSLLTLQHPFFVDIKDAMKKEAAELGVKVVVADANGDLAKQLSQIEDFIQQGVDAIILAPVDSGG 68
PBP1_rhizopine_binding-like cd06301
periplasmic binding proteins specific to rhizopines; Periplasmic binding proteins specific to ...
 67-112 7.91e-05

periplasmic binding proteins specific to rhizopines; Periplasmic binding proteins specific to rhizopines, which are simple sugar-like compounds produced in the nodules induced by the symbiotic root nodule bacteria, such as Rhizobium and Sinorhizobium. Rhizopine-binding-like proteins from other bacteria are also included. Two inositol based rhizopine compounds are known to date: L-3-O-methly-scyllo-inosamine (3-O-MSI) and scyllo-inosamine. Bacterial strains that can metabolize rhizopine have a greater competitive advantage in nodulation and rhizopine synthesis is regulated by NifA/NtrA regulatory transcription activators which are maximally expressed at the onset of nitrogen fixation in bacteroids. The members of this group belong to the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily.


Pssm-ID: 380524 [Multi-domain]  Cd Length: 272  Bit Score: 41.06  E-value: 7.91e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2731651628  67 MGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd06301    30 PGVKLVIVDAQSDAAKQLSQVENFIAQGVDAIIVNPVDTDASAPAV 75
PBP1_ribose_binding cd06323
periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose ...
 41-109 2.49e-04

periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis D-ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group belong to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.


Pssm-ID: 380546 [Multi-domain]  Cd Length: 268  Bit Score: 39.59  E-value: 2.49e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2731651628  41 IGLALPTTVSARWILDGENLEYEFDRMGYTTELQYADDDVAKQVSQVEAMIDSGARALVVGAVSATALT 109
Cdd:cd06323     2 IGLSVSTLNNPFFVSLKDGAQAEAKELGVELVVLDAQNDPAKQLSQVEDLIVRKVDALLINPTDSDAVS 70
PBP1_ABC_sugar_binding-like cd06300
periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are ...
 76-112 3.13e-04

periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily; Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.


Pssm-ID: 380523 [Multi-domain]  Cd Length: 302  Bit Score: 39.23  E-value: 3.13e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2731651628  76 ADDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd06300    42 SNGDATEQIAQIRNLIDQGVDAIIINPSSPTALNAVI 78
PBP1_ABC_sugar_binding-like cd06310
monosaccharide ABC transporter substrate-binding protein such as CUT2; Periplasmic ...
 40-112 3.53e-04

monosaccharide ABC transporter substrate-binding protein such as CUT2; Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.


Pssm-ID: 380533 [Multi-domain]  Cd Length: 272  Bit Score: 38.86  E-value: 3.53e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2731651628  40 RIGLALPTTVSARWILDGENLEYEFDRMGYTTELQYA--DDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd06310     1 KIGVVLKGTTSAFWRTVREGAEAAAKDLGVKIIFVGPesEEDVAGQNSLLEELINKKPDAIVVAPLDSEDLVDPL 75
PBP1_TorT-like cd06306
TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor ...
 77-112 6.45e-04

TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria. The Tor respiratory system is consists of three proteins (TorC, TorA, and TorD) and is induced in the presence of TMAO. The TMAO control is tightly regulated by three proteins: TorS, TorT, and TorR. Thus, the disruption of any of these proteins can abolish the Tor respiratory induction. TorT shares homology with the sugar-binding domain of the type 1 periplasmic binding proteins. The members of TorT-like family bind TMAO or related compounds and are predicted to be involved in signal transduction and/or substrate transport.


Pssm-ID: 380529 [Multi-domain]  Cd Length: 269  Bit Score: 38.33  E-value: 6.45e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2731651628  77 DDDVAKQVSQVEAMIDSGARALVVGAVSATALTDVL 112
Cdd:cd06306    40 YTNLSKQISQLEDCVASGADAILLGAISFDGLDPKV 75
PBP1_ABC_sugar_binding-like cd19997
monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic ...
 76-108 3.05e-03

monosaccharide ABC transporter substrate binding protein such as CUT2; Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.


Pssm-ID: 380652 [Multi-domain]  Cd Length: 305  Bit Score: 36.50  E-value: 3.05e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2731651628  76 ADDDVAKQVSQVEAMIDSGARALVVGAVSATAL 108
Cdd:cd19997    42 ADGSATTQISQIQNLILQGVDAIVIDAASPTAL 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH