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Conserved domains on  [gi|2734853729|ref|WP_346732943|]
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SUMF1/EgtB/PvdO family nonheme iron enzyme [Planktothrix agardhii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YfmG COG1262
Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain ...
 694-915 6.39e-109

Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440874 [Multi-domain]  Cd Length: 238  Bit Score: 335.82  E-value: 6.39e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 694 GNNISLEMVSIPGGTFMMGAVQNEAnASSDEYPQHPVNIAAFSMAKYPITQAQWEAIMG-------NNP--SNFKGANRP 764
Cdd:COG1262     6 GNAVGLEMVLIPGGTFLMGSPEGEG-AFDNERPRHRVTVSPFYIDKYEVTNAEYRAFVGwtladgrNNPlySDFGGPDHP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 765 VENVNWHQAQEFCQRLSQETGKTYRLPSEAEWEYACRAKTTTPFHFGETITADLANYECN--RNQTTDVGSFPPNAFGLY 842
Cdd:COG1262    85 VVHVSWYDAQAYCRWLGKKTGKGYRLPTEAEWEYAARGGDGRPYPWGDDLPPELANYAGNdgRGSTAPVGSFPPNPFGLY 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 843 DMHGNVWEWCADPWHENYTGAPDNGSVWESGGNtqLRCVRGGSWIYVPDICRSANRYAERPDVFVSSIGFRVC 915
Cdd:COG1262   165 DMAGNVWEWTADWYDPPYPGAPADGPVGPENGG--QRVLRGGSWATPPDHLRSAYRNFFPPDARWQFVGFRLA 235
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
537-651 8.50e-32

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 123.87  E-value: 8.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4785    77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNRDVAQGVWDEK 651
Cdd:COG4785   157 YELAIADLEKALELDPNDPERALWLYLAERKLDPE 191
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 47-116 1.38e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


:

Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 42.95  E-value: 1.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729  47 AEMEEKRQQIQLAQYKLQCVQVANNAIIEEKRQEIQLEQIKLQYIENQKNREFQKELQEYIQSVNLAINK 116
Cdd:pfam03938  33 AELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQQKAQQELQKKQQELLQPIQDKINK 102
PRK15471 super family cl33153
chain length determinant protein WzzB; Provisional
 100-167 4.15e-04

chain length determinant protein WzzB; Provisional


The actual alignment was detected with superfamily member PRK15471:

Pssm-ID: 185368 [Multi-domain]  Cd Length: 325  Bit Score: 43.59  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 100 QKELQEYIQSVNLAINK-------SNIEfqrwrfEQEKTLQKELttygrETQLMVAEYQRETAIKVAH------NQAEVQ 166
Cdd:PRK15471  145 QKKLAQYIQQVDDQVAKelekdlkDNIA------LRTKTLQDSL-----ETQEVVAQEQKDLRIKQIQealqyaNQANIT 213


                  .
gi 2734853729 167 K 167
Cdd:PRK15471  214 K 214
 
Name Accession Description Interval E-value
YfmG COG1262
Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain ...
 694-915 6.39e-109

Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440874 [Multi-domain]  Cd Length: 238  Bit Score: 335.82  E-value: 6.39e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 694 GNNISLEMVSIPGGTFMMGAVQNEAnASSDEYPQHPVNIAAFSMAKYPITQAQWEAIMG-------NNP--SNFKGANRP 764
Cdd:COG1262     6 GNAVGLEMVLIPGGTFLMGSPEGEG-AFDNERPRHRVTVSPFYIDKYEVTNAEYRAFVGwtladgrNNPlySDFGGPDHP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 765 VENVNWHQAQEFCQRLSQETGKTYRLPSEAEWEYACRAKTTTPFHFGETITADLANYECN--RNQTTDVGSFPPNAFGLY 842
Cdd:COG1262    85 VVHVSWYDAQAYCRWLGKKTGKGYRLPTEAEWEYAARGGDGRPYPWGDDLPPELANYAGNdgRGSTAPVGSFPPNPFGLY 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 843 DMHGNVWEWCADPWHENYTGAPDNGSVWESGGNtqLRCVRGGSWIYVPDICRSANRYAERPDVFVSSIGFRVC 915
Cdd:COG1262   165 DMAGNVWEWTADWYDPPYPGAPADGPVGPENGG--QRVLRGGSWATPPDHLRSAYRNFFPPDARWQFVGFRLA 235
FGE-sulfatase pfam03781
Sulfatase-modifying factor enzyme 1; This domain is found in eukaryotic proteins required for ...
 700-914 1.47e-63

Sulfatase-modifying factor enzyme 1; This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.


Pssm-ID: 397722 [Multi-domain]  Cd Length: 259  Bit Score: 215.05  E-value: 1.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 700 EMVSIPGGTFMMGAvqNEANASSDEYPQHPVNIAAFSMAKYPITQAQWEAIM--------------------------GN 753
Cdd:pfam03781   4 DMVLIPGGSFEMGS--AERTGNDNEAPAHDVTVRPFAIDKYPVTNAQYAAFVeatgyttevypqwwaeveganwrhpsGG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 754 NPSNFKGANRPVENVNWHQAQEFCQRLSQETGKTYRLPSEAEWEYACRA-KTTTPFHFGETITADL------------AN 820
Cdd:pfam03781  82 LSDIDDGADHPVTGVSWYDAVAYARWLGKRTGNGYRLPTEAEWEYAARGgSKGRRYPWGDELYPAGniwqgadfpnehAG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 821 YECNRNQTTDVGSFPPNAFGLYDMHGNVWEWCADPWHENYTGAPDNGSVWESGGNTQlRCVRGGSWIY--VPDICRSANR 898
Cdd:pfam03781 162 ADSFNGRTSPVGSFPPNALGLYDMAGNVWEWTSDWYKPHYSFAPYDELSRDNFGGGY-RVVRGGSWACsvYPSRLRPAFR 240

                         250
                  ....*....|....*..
gi 2734853729 899 -YAERPDVFVSSIGFRV 914
Cdd:pfam03781 241 gNCQTPGTRADDVGFRL 257
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
537-651 8.50e-32

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 123.87  E-value: 8.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4785    77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNRDVAQGVWDEK 651
Cdd:COG4785   157 YELAIADLEKALELDPNDPERALWLYLAERKLDPE 191
egtB_TIGR03440 TIGR03440
ergothioneine biosynthesis protein EgtB; Members of this family include EgtB, and enzyme of ...
 694-915 5.31e-25

ergothioneine biosynthesis protein EgtB; Members of this family include EgtB, and enzyme of the ergothioneine biosynthesis, as found in numerous Actinobacteria. Characterized homologs to this family include a formylglycine-generating enzyme that serves as a maturase for an aerobic sulfatase (cf. the radical SAM enzymes that serve as anaerobic sulfatase maturases). [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 274581 [Multi-domain]  Cd Length: 406  Bit Score: 108.57  E-value: 5.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 694 GNNISLEMVSIPGGTFMMGAvQNEANASSDEYPQHPVNIAAFSMAKYPITQAQ--------------------WEAIMGN 753
Cdd:TIGR03440 163 ASAPPLRWVAFPGGEFEIGS-DADGFAFDNERPRHRVLVPPFEIDARPVTNGEylefiedggyrrpelwlsdgWAWVQAE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 754 N---P------------SNFKG-----ANRPVENVNWHQAQEFCqRLSqetGKtyRLPSEAEWEYACRAKTTTPfHFGET 813
Cdd:TIGR03440 242 GwqaPlywrrddgtwwvFTLGGlrpldPDAPVCHVSYYEADAYA-RWA---GA--RLPTEAEWEKAARWGDAPP-NFAEA 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 814 itadlanyecnrNQTTDVGSFPPNAFGLYDMHGNVWEWCADPWhENYTG-APDNGSVWESGG---NTQlRCVRGGSWIYV 889
Cdd:TIGR03440 315 ------------NLGAPVGAYPAGAQGLGQLFGDVWEWTASPY-EPYPGfRPPPGAYGEYNGkfmDGQ-MVLRGGSCATP 380

                         250       260
                  ....*....|....*....|....*....
gi 2734853729 890 PDICRSANR---YAERPDVFVssiGFRVC 915
Cdd:TIGR03440 381 PRHLRPSYRnffYPHRRWQFS---GFRLA 406
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 514-635 3.92e-11

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 64.91  E-value: 3.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 514 IEKINNLLESLGETHRvnivkicyQRGKNHYQQGEY-------TTAIDDFTQVLLLKPNSPDAnYNR-GLAYGKLGEYSA 585
Cdd:PRK11189   46 LARLNQILASRDLTDE--------ERAQLHYERGVLydslglrALARNDFSQALALRPDMADA-YNYlGIYLTQAGNFDA 116

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2734853729 586 AIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLP 635
Cdd:PRK11189  117 AYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDPNDP 166
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 538-629 1.11e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 62.31  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 538 QRGKNHYQQGEYTTAIDDFTQVLLLKPNsPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEY 617
Cdd:TIGR00990 132 EKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKY 210

                          90
                  ....*....|...
gi 2734853729 618 EKAIADYN-SCLV 629
Cdd:TIGR00990 211 ADALLDLTaSCII 223
TPR_11 pfam13414
TPR repeat;
574-615 2.78e-09

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 53.24  E-value: 2.78e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2734853729 574 GLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLG 615
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 602-633 3.91e-08

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 49.75  E-value: 3.91e-08
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2734853729  602 RAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 47-116 1.38e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 42.95  E-value: 1.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729  47 AEMEEKRQQIQLAQYKLQCVQVANNAIIEEKRQEIQLEQIKLQYIENQKNREFQKELQEYIQSVNLAINK 116
Cdd:pfam03938  33 AELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQQKAQQELQKKQQELLQPIQDKINK 102
PRK15471 PRK15471
chain length determinant protein WzzB; Provisional
 100-167 4.15e-04

chain length determinant protein WzzB; Provisional


Pssm-ID: 185368 [Multi-domain]  Cd Length: 325  Bit Score: 43.59  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 100 QKELQEYIQSVNLAINK-------SNIEfqrwrfEQEKTLQKELttygrETQLMVAEYQRETAIKVAH------NQAEVQ 166
Cdd:PRK15471  145 QKKLAQYIQQVDDQVAKelekdlkDNIA------LRTKTLQDSL-----ETQEVVAQEQKDLRIKQIQealqyaNQANIT 213


                  .
gi 2734853729 167 K 167
Cdd:PRK15471  214 K 214
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 581-633 7.27e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.27e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 581 GEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:cd24142    14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
 
Name Accession Description Interval E-value
YfmG COG1262
Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain ...
 694-915 6.39e-109

Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440874 [Multi-domain]  Cd Length: 238  Bit Score: 335.82  E-value: 6.39e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 694 GNNISLEMVSIPGGTFMMGAVQNEAnASSDEYPQHPVNIAAFSMAKYPITQAQWEAIMG-------NNP--SNFKGANRP 764
Cdd:COG1262     6 GNAVGLEMVLIPGGTFLMGSPEGEG-AFDNERPRHRVTVSPFYIDKYEVTNAEYRAFVGwtladgrNNPlySDFGGPDHP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 765 VENVNWHQAQEFCQRLSQETGKTYRLPSEAEWEYACRAKTTTPFHFGETITADLANYECN--RNQTTDVGSFPPNAFGLY 842
Cdd:COG1262    85 VVHVSWYDAQAYCRWLGKKTGKGYRLPTEAEWEYAARGGDGRPYPWGDDLPPELANYAGNdgRGSTAPVGSFPPNPFGLY 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 843 DMHGNVWEWCADPWHENYTGAPDNGSVWESGGNtqLRCVRGGSWIYVPDICRSANRYAERPDVFVSSIGFRVC 915
Cdd:COG1262   165 DMAGNVWEWTADWYDPPYPGAPADGPVGPENGG--QRVLRGGSWATPPDHLRSAYRNFFPPDARWQFVGFRLA 235
FGE-sulfatase pfam03781
Sulfatase-modifying factor enzyme 1; This domain is found in eukaryotic proteins required for ...
 700-914 1.47e-63

Sulfatase-modifying factor enzyme 1; This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.


Pssm-ID: 397722 [Multi-domain]  Cd Length: 259  Bit Score: 215.05  E-value: 1.47e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 700 EMVSIPGGTFMMGAvqNEANASSDEYPQHPVNIAAFSMAKYPITQAQWEAIM--------------------------GN 753
Cdd:pfam03781   4 DMVLIPGGSFEMGS--AERTGNDNEAPAHDVTVRPFAIDKYPVTNAQYAAFVeatgyttevypqwwaeveganwrhpsGG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 754 NPSNFKGANRPVENVNWHQAQEFCQRLSQETGKTYRLPSEAEWEYACRA-KTTTPFHFGETITADL------------AN 820
Cdd:pfam03781  82 LSDIDDGADHPVTGVSWYDAVAYARWLGKRTGNGYRLPTEAEWEYAARGgSKGRRYPWGDELYPAGniwqgadfpnehAG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 821 YECNRNQTTDVGSFPPNAFGLYDMHGNVWEWCADPWHENYTGAPDNGSVWESGGNTQlRCVRGGSWIY--VPDICRSANR 898
Cdd:pfam03781 162 ADSFNGRTSPVGSFPPNALGLYDMAGNVWEWTSDWYKPHYSFAPYDELSRDNFGGGY-RVVRGGSWACsvYPSRLRPAFR 240

                         250
                  ....*....|....*..
gi 2734853729 899 -YAERPDVFVSSIGFRV 914
Cdd:pfam03781 241 gNCQTPGTRADDVGFRL 257
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
537-651 8.50e-32

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 123.87  E-value: 8.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4785    77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNRDVAQGVWDEK 651
Cdd:COG4785   157 YELAIADLEKALELDPNDPERALWLYLAERKLDPE 191
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
537-641 1.08e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 112.79  E-value: 1.08e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG0457    12 NNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGR 91

                          90       100
                  ....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG0457    92 YEEALEDYDKALELDPDDAEALYNL 116
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
537-644 2.92e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 111.64  E-value: 2.92e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG0457    46 YNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGR 125

                          90       100
                  ....*....|....*....|....*...
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNRDVA 644
Cdd:COG0457   126 YDEAIEAYERALELDPDDADALYNLGIA 153
egtB_TIGR03440 TIGR03440
ergothioneine biosynthesis protein EgtB; Members of this family include EgtB, and enzyme of ...
 694-915 5.31e-25

ergothioneine biosynthesis protein EgtB; Members of this family include EgtB, and enzyme of the ergothioneine biosynthesis, as found in numerous Actinobacteria. Characterized homologs to this family include a formylglycine-generating enzyme that serves as a maturase for an aerobic sulfatase (cf. the radical SAM enzymes that serve as anaerobic sulfatase maturases). [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 274581 [Multi-domain]  Cd Length: 406  Bit Score: 108.57  E-value: 5.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 694 GNNISLEMVSIPGGTFMMGAvQNEANASSDEYPQHPVNIAAFSMAKYPITQAQ--------------------WEAIMGN 753
Cdd:TIGR03440 163 ASAPPLRWVAFPGGEFEIGS-DADGFAFDNERPRHRVLVPPFEIDARPVTNGEylefiedggyrrpelwlsdgWAWVQAE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 754 N---P------------SNFKG-----ANRPVENVNWHQAQEFCqRLSqetGKtyRLPSEAEWEYACRAKTTTPfHFGET 813
Cdd:TIGR03440 242 GwqaPlywrrddgtwwvFTLGGlrpldPDAPVCHVSYYEADAYA-RWA---GA--RLPTEAEWEKAARWGDAPP-NFAEA 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 814 itadlanyecnrNQTTDVGSFPPNAFGLYDMHGNVWEWCADPWhENYTG-APDNGSVWESGG---NTQlRCVRGGSWIYV 889
Cdd:TIGR03440 315 ------------NLGAPVGAYPAGAQGLGQLFGDVWEWTASPY-EPYPGfRPPPGAYGEYNGkfmDGQ-MVLRGGSCATP 380

                         250       260
                  ....*....|....*....|....*....
gi 2734853729 890 PDICRSANR---YAERPDVFVssiGFRVC 915
Cdd:TIGR03440 381 PRHLRPSYRnffYPHRRWQFS---GFRLA 406
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
561-644 3.87e-22

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 95.75  E-value: 3.87e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 561 LLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146


                  ....
gi 2734853729 641 RDVA 644
Cdd:COG4785   147 RGIA 150
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
537-625 1.81e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 94.69  E-value: 1.81e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG0457    80 NNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGR 159


                  ....*....
gi 2734853729 617 YEKAIADYN 625
Cdd:COG0457   160 YEEALELLE 168
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
562-641 6.93e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 92.76  E-value: 6.93e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 562 LKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 537-641 1.02e-20

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 89.10  E-value: 1.02e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGD 87

                          90       100
                  ....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG4783    88 YDEALALLEKALKLDPEHPEAYLRL 112
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 543-632 1.74e-20

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 89.25  E-value: 1.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 543 HYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIA 622
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                          90
                  ....*....|
gi 2734853729 623 DYNSCLVLNP 632
Cdd:COG5010   144 ALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 531-641 3.90e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.83  E-value: 3.90e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 531 NIVKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANT 610
Cdd:COG3914   110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNA 189

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2734853729 611 YYKLGEYEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG3914   190 LQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
543-634 1.06e-19

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 84.84  E-value: 1.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 543 HYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEdYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIA 622
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|..
gi 2734853729 623 DYNSCLVLNPNL 634
Cdd:COG3063    81 YLERALELDPSA 92
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 537-633 4.89e-19

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 84.47  E-value: 4.89e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4783    42 ALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121

                          90
                  ....*....|....*..
gi 2734853729 617 YEKAIADYNSCLVLNPN 633
Cdd:COG4783   122 PDEAIAALEKALELDPD 138
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 537-641 1.09e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.21  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG3914    82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                          90       100
                  ....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG3914   162 LEEAIAALRRALELDPDNAEALNNL 186
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 537-633 6.00e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 80.82  E-value: 6.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG4235    21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100

                          90
                  ....*....|....*..
gi 2734853729 617 YEKAIADYNSCLVLNPN 633
Cdd:COG4235   101 YAEAIAAWQKLLALLPA 117
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 537-637 8.24e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.70  E-value: 8.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90       100
                  ....*....|....*....|.
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDV 637
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEA 112
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 535-637 8.64e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.70  E-value: 8.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 535 ICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKL 614
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                          90       100
                  ....*....|....*....|...
gi 2734853729 615 GEYEKAIADYNSCLVLNPNLPDV 637
Cdd:COG2956   226 GDPEEALELLRKALELDPSDDLL 248
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 537-640 2.02e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.46  E-value: 2.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:COG2956   114 RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGD 193

                          90       100
                  ....*....|....*....|....
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:COG2956   194 YEEAIAALERALEQDPDYLPALPR 217
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 575-644 5.43e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 70.37  E-value: 5.43e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 575 LAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHNRDVA 644
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 541-633 8.90e-14

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 68.48  E-value: 8.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 541 KNHYQQGEYTTAIDDFTQVLLLKPNS---PDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN---YLRAYNNRANTYYKL 614
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLEL 80

                          90
                  ....*....|....*....
gi 2734853729 615 GEYEKAIADYNSCLVLNPN 633
Cdd:COG1729    81 GDYDKARATLEELIKKYPD 99
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 514-637 3.27e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 3.27e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 514 IEKINNLLESLGETHRVNivkicYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQT 593
Cdd:COG2956    62 IRIHQKLLERDPDRAEAL-----LELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL 136

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2734853729 594 LRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDV 637
Cdd:COG2956   137 LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA 180
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 552-637 4.35e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 66.95  E-value: 4.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 552 AIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLN 631
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81


                  ....*.
gi 2734853729 632 PNLPDV 637
Cdd:COG4235    82 PDNPEA 87
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 533-640 1.35e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 533 VKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYY 612
Cdd:COG2956    42 VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE 121

                          90       100
                  ....*....|....*....|....*...
gi 2734853729 613 KLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:COG2956   122 QEGDWEKAIEVLERLLKLGPENAHAYCE 149
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
576-641 2.40e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 63.65  E-value: 2.40e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 576 AYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIAdYNSCLVLNPNLPDVAHNR 641
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNL 65
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 568-650 3.19e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.13  E-value: 3.19e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 568 DANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHNR---DVA 644
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLglaLLK 84


                  ....*.
gi 2734853729 645 QGVWDE 650
Cdd:COG4783    85 AGDYDE 90
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 514-635 3.92e-11

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 64.91  E-value: 3.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 514 IEKINNLLESLGETHRvnivkicyQRGKNHYQQGEY-------TTAIDDFTQVLLLKPNSPDAnYNR-GLAYGKLGEYSA 585
Cdd:PRK11189   46 LARLNQILASRDLTDE--------ERAQLHYERGVLydslglrALARNDFSQALALRPDMADA-YNYlGIYLTQAGNFDA 116

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2734853729 586 AIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLP 635
Cdd:PRK11189  117 AYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDPNDP 166
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
531-645 6.97e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 6.97e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 531 NIVKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANT 610
Cdd:COG0457   108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAA 187

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2734853729 611 YYKLGEYEKAIADYNSCLVLNPNLPDVAHNRDVAQ 645
Cdd:COG0457   188 LALAAAEVLLALLLALEQALRKKLAILTLAALAEL 222
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 538-629 1.11e-09

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 62.31  E-value: 1.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 538 QRGKNHYQQGEYTTAIDDFTQVLLLKPNsPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEY 617
Cdd:TIGR00990 132 EKGNKAYRNKDFNKAIKLYSKAIECKPD-PVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKY 210

                          90
                  ....*....|...
gi 2734853729 618 EKAIADYN-SCLV 629
Cdd:TIGR00990 211 ADALLDLTaSCII 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 537-598 2.06e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.28  E-value: 2.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNP 598
Cdd:COG5010    92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
561-645 2.09e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.77  E-value: 2.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 561 LLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRlNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:COG4785    34 VLALAIALADLALALAAAALAAAALAAERIDRALA-LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNN 112


                  ....*
gi 2734853729 641 RDVAQ 645
Cdd:COG4785   113 RGLAY 117
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 529-622 2.20e-09

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 58.89  E-value: 2.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 529 RVNIVKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRA 608
Cdd:TIGR02521  27 RNKAAKIRVQLALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYG 106

                          90
                  ....*....|....
gi 2734853729 609 NTYYKLGEYEKAIA 622
Cdd:TIGR02521 107 TFLCQQGKYEQAMQ 120
TPR_11 pfam13414
TPR repeat;
574-615 2.78e-09

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 53.24  E-value: 2.78e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2734853729 574 GLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLG 615
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_1 pfam00515
Tetratricopeptide repeat;
602-633 6.97e-09

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 52.04  E-value: 6.97e-09
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2734853729 602 RAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 539-622 8.68e-09

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 58.26  E-value: 8.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 539 RGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYE 618
Cdd:PLN03088    8 KAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQ 87


                  ....
gi 2734853729 619 KAIA 622
Cdd:PLN03088   88 TAKA 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 537-600 1.13e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.81  E-value: 1.13e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNY 600
Cdd:COG4783    76 LNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
594-641 1.30e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.55  E-value: 1.30e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2734853729 594 LRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL 48
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 537-599 2.35e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 53.07  E-value: 2.35e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNS---PDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN 599
Cdd:COG1729    34 YWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 537-616 3.08e-08

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 54.29  E-value: 3.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDAN---YNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYK 613
Cdd:PRK02603   39 YRDGMSAQADGEYAEALENYEEALKLEEDPNDRSyilYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHK 118


                  ...
gi 2734853729 614 LGE 616
Cdd:PRK02603  119 RGE 121
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
537-602 3.09e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.09  E-value: 3.09e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 537 YQRGKNHYQQGEYTTAIDdFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLR 602
Cdd:COG3063    30 NNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 547-637 3.52e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 57.30  E-value: 3.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 547 GEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNS 626
Cdd:TIGR00990 379 GDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRR 458

                          90
                  ....*....|.
gi 2734853729 627 CLVLNPNLPDV 637
Cdd:TIGR00990 459 CKKNFPEAPDV 469
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 602-633 3.91e-08

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 49.75  E-value: 3.91e-08
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2734853729  602 RAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
567-600 5.83e-08

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 49.34  E-value: 5.83e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2734853729 567 PDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNY 600
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 537-625 7.93e-08

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 54.50  E-value: 7.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSP---DANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN--------YLRAYn 605
Cdd:COG4105    36 YEEAKEALEKGDYEKAIKLFEELEPRYPGSPyaeQAQLMLAYAYYKQGDYEEAIAAADRFIKLYPNspnadyayYLRGL- 114

                          90       100
                  ....*....|....*....|....*...
gi 2734853729 606 nranTYYKL--------GEYEKAIADYN 625
Cdd:COG4105   115 ----SYYEQspdsdrdqTSTRKAIEAFQ 138
TPR_11 pfam13414
TPR repeat;
540-581 1.33e-07

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 48.62  E-value: 1.33e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2734853729 540 GKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLG 581
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 571-635 2.59e-07

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 48.49  E-value: 2.59e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2734853729 571 YNRGLAYGKLGEYSAAIEDYNQTLRLN---PNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLP 635
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 537-623 3.62e-07

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 49.99  E-value: 3.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:TIGR02552  21 YALAYNLYQQGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGE 100


                  ....*..
gi 2734853729 617 YEKAIAD 623
Cdd:TIGR02552 101 PESALKA 107
TPR_12 pfam13424
Tetratricopeptide repeat;
569-628 3.81e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 48.54  E-value: 3.81e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2734853729 569 ANYNRGLAYGKLGEYSAAIEDYNQTLRL--------NPNYLRAYNNRANTYYKLGEYEKAIADYNSCL 628
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 567-600 7.02e-07

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 46.29  E-value: 7.02e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2734853729  567 PDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNY 600
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 561-638 7.13e-07

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 51.42  E-value: 7.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 561 LLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN---YLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDV 637
Cdd:COG4105    26 ALKSWDAEELYEEAKEALEKGDYEKAIKLFEELEPRYPGspyAEQAQLMLAYAYYKQGDYEEAIAAADRFIKLYPNSPNA 105


                  .
gi 2734853729 638 A 638
Cdd:COG4105   106 D 106
ycf3 CHL00033
photosystem I assembly protein Ycf3
 537-616 8.42e-07

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 50.01  E-value: 8.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDAN---YNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYK 613
Cdd:CHL00033   39 YRDGMSAQSEGEYAEALQNYYEAMRLEIDPYDRSyilYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMAVICHY 118


                  ...
gi 2734853729 614 LGE 616
Cdd:CHL00033  119 RGE 121
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 537-600 1.37e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 46.56  E-value: 1.37e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPD---ANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNY 600
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 585-637 1.69e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 1.69e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 585 AAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDV 637
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADA 53
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 571-640 2.31e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 48.90  E-value: 2.31e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2734853729 571 YNRGLAYGKLGEYSAAIEDYNQTLRL--NPNYlRAY--NNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:PRK02603   39 YRDGMSAQADGEYAEALENYEEALKLeeDPND-RSYilYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNN 111
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 537-614 2.72e-06

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 49.47  E-value: 2.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSP----------DANYnrglaygKLGEYSAAIEDYNQTLRLNPN-----Yl 601
Cdd:TIGR03302  37 YEEAKEALDSGDYTEAIKYFEALESRYPFSPyaeqaqldlaYAYY-------KSGDYAEAIAAADRFIRLHPNhpdadY- 108

                          90
                  ....*....|...
gi 2734853729 602 rAYNNRANTYYKL 614
Cdd:TIGR03302 109 -AYYLRGLSNYNQ 120
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 602-633 3.46e-06

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 44.44  E-value: 3.46e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2734853729 602 RAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_9 pfam13371
Tetratricopeptide repeat;
543-598 5.27e-06

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 44.90  E-value: 5.27e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 543 HYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNP 598
Cdd:pfam13371   5 YLREEDWERALAVVERLLLLAPDDPEERRDRGLLYAQLGCFQAALEDLEAYLELAP 60
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 566-638 5.57e-06

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 48.70  E-value: 5.57e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 566 SPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNP--NYLR-AYNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVA 638
Cdd:TIGR03302  32 PAEELYEEAKEALDSGDYTEAIKYFEALESRYPfsPYAEqAQLDLAYAYYKSGDYAEAIAAADRFIRLHPNHPDAD 107
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 540-640 5.92e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 5.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 540 GKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN-----------YLRA----- 603
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPElgradlllilsYLRSgqfdk 449

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2734853729 604 ------------------YNNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:TIGR02917 450 alaaakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAAN 504
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 537-635 1.21e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:TIGR02917 265 YLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGR 344

                          90
                  ....*....|....*....
gi 2734853729 617 YEKAIADYNSCLVLNPNLP 635
Cdd:TIGR02917 345 VDEAIATLSPALGLDPDDP 363
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 582-634 3.21e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.09  E-value: 3.21e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 582 EYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPNL 634
Cdd:PLN03088   17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSL 69
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 567-599 3.24e-05

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 41.74  E-value: 3.24e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2734853729 567 PDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN 599
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 539-633 3.47e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 47.67  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 539 RGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYE 618
Cdd:TIGR00990 337 RGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFA 416

                          90
                  ....*....|....*
gi 2734853729 619 KAIADYNSCLVLNPN 633
Cdd:TIGR00990 417 QAGKDYQKSIDLDPD 431
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 545-635 4.92e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 4.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 545 QQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADY 624
Cdd:TIGR02917 239 EAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYL 318

                          90
                  ....*....|.
gi 2734853729 625 NSCLVLNPNLP 635
Cdd:TIGR02917 319 NQILKYAPNSH 329
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 540-642 5.74e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 5.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 540 GKNHYQQGEYTTAIDDFTQVLLLKPNSPDAnYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEK 619
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDK 788

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2734853729 620 AIADY--------NSCLVLNpNLPDVAHNRD 642
Cdd:TIGR02917 789 AIKHYqtvvkkapDNAVVLN-NLAWLYLELK 818
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 510-605 7.28e-05

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 44.28  E-value: 7.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 510 DLDYIEKINNLLESLG-ETHRVNIVKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGE------ 582
Cdd:PRK02603   48 DGEYAEALENYEEALKlEEDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEkaeeag 127

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2734853729 583 --------YSAAIEDYNQTLRLNP-NYLRAYN 605
Cdd:PRK02603  128 dqdeaealFDKAAEYWKQAIRLAPnNYIEAQN 159
TPR_11 pfam13414
TPR repeat;
608-645 1.20e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 40.15  E-value: 1.20e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2734853729 608 ANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHNRDVAQ 645
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAY 38
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 539-641 1.33e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 539 RGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYnrGLAYGKL--GEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGE 616
Cdd:TIGR02917 131 RGLAYLGLGQLELAQKSYEQALAIDPRSLYAKL--GLAQLALaeNRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGN 208

                          90       100
                  ....*....|....*....|....*
gi 2734853729 617 YEKAIADYNSCLVLNPNLPDVAHNR 641
Cdd:TIGR02917 209 IELALAAYRKAIALRPNNIAVLLAL 233
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 47-116 1.38e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 42.95  E-value: 1.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729  47 AEMEEKRQQIQLAQYKLQCVQVANNAIIEEKRQEIQLEQIKLQYIENQKNREFQKELQEYIQSVNLAINK 116
Cdd:pfam03938  33 AELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQELQQLQQKAQQELQKKQQELLQPIQDKINK 102
TPR_17 pfam13431
Tetratricopeptide repeat;
590-622 2.27e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.06  E-value: 2.27e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2734853729 590 YNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIA 622
Cdd:pfam13431   2 YLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 551-641 2.29e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 2.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 551 TAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVL 630
Cdd:COG5010     4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                          90
                  ....*....|.
gi 2734853729 631 NPNLPDVAHNR 641
Cdd:COG5010    84 DPNNPELYYNL 94
TPR_8 pfam13181
Tetratricopeptide repeat;
601-633 2.52e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 38.92  E-value: 2.52e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2734853729 601 LRAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 537-622 2.72e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 2.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYN--QTLRLNPNYLRAYNNRAntYYKL 614
Cdd:TIGR02917  26 IEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRkaLSLGYPKNQVLPLLARA--YLLQ 103


                  ....*...
gi 2734853729 615 GEYEKAIA 622
Cdd:TIGR02917 104 GKFQQVLD 111
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 544-633 2.74e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 2.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 544 YQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIAD 623
Cdd:TIGR02917 204 LSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARET 283

                          90
                  ....*....|
gi 2734853729 624 YNSCLVLNPN 633
Cdd:TIGR02917 284 LQDALKSAPE 293
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 537-636 2.88e-04

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 43.72  E-value: 2.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 537 YQRGKNHYQQG-------EYT-TAIDDFTQVLLLKPNS---PDANY------NRgLA---------YGKLGEYSAAI--- 587
Cdd:COG4105   110 YLRGLSYYEQSpdsdrdqTSTrKAIEAFQELINRYPDSeyaEDAKKridelrDK-LArkelevaryYLKRGAYVAAInrf 188

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 588 ----EDYNQTlrlnPNYLRAYNNRANTYYKLGEYEKAIADYNsclVLNPNLPD 636
Cdd:COG4105   189 qnvlEDYPDT----PAVEEALYLLVEAYYALGRYDEAQDAAA---VLGKNYPD 234
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 546-638 2.89e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 2.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 546 QGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYN 625
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAD 251

                          90
                  ....*....|...
gi 2734853729 626 SCLVLNPNLPDVA 638
Cdd:TIGR02917 252 ALLKKAPNSPLAH 264
YfiO pfam13525
Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards ...
 537-599 4.11e-04

Outer membrane lipoprotein; This outer membrane lipoprotein carries a TPR-like region towards its N-terminal. YfiO in E.coli is one of three outer membrane lipoproteins that form a multicomponent YaeT complex in the outer membrane of Gram-negative bacteria that is involved in the targeting and folding of beta-barrel outer membrane proteins. YfiO is the only essential lipoprotein component of the complex. It is required for the proper assembly and/or targeting of outer membrane proteins to the outer membrane. Through its interactions with NlpB it maintains the functional integrity of the YaeT complex.


Pssm-ID: 433282 [Multi-domain]  Cd Length: 200  Bit Score: 42.70  E-value: 4.11e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVLLLKPNSP---DANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN 599
Cdd:pfam13525   8 YEAGQTALQKGDYGDAIKKLEALDNRYPFSPyaeQAQLDLIYAYYKDADYADALAAAERFLRLYPT 73
PRK15471 PRK15471
chain length determinant protein WzzB; Provisional
 100-167 4.15e-04

chain length determinant protein WzzB; Provisional


Pssm-ID: 185368 [Multi-domain]  Cd Length: 325  Bit Score: 43.59  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 100 QKELQEYIQSVNLAINK-------SNIEfqrwrfEQEKTLQKELttygrETQLMVAEYQRETAIKVAH------NQAEVQ 166
Cdd:PRK15471  145 QKKLAQYIQQVDDQVAKelekdlkDNIA------LRTKTLQDSL-----ETQEVVAQEQKDLRIKQIQealqyaNQANIT 213


                  .
gi 2734853729 167 K 167
Cdd:PRK15471  214 K 214
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 543-621 5.40e-04

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 42.56  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 543 HYQQGEYTTAIDDFTQVLLLKPNSPD---ANYNRGLAYGKLGEYS--------AAIEDYNQTLRLNPN------------ 599
Cdd:COG4105    79 YYKQGDYEEAIAAADRFIKLYPNSPNadyAYYLRGLSYYEQSPDSdrdqtstrKAIEAFQELINRYPDseyaedakkrid 158

                          90       100
                  ....*....|....*....|....*...
gi 2734853729 600 YLR------AYNNrANTYYKLGEYEKAI 621
Cdd:COG4105   159 ELRdklarkELEV-ARYYLKRGAYVAAI 185
TPR_19 pfam14559
Tetratricopeptide repeat;
581-622 6.32e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 6.32e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2734853729 581 GEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIA 622
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEA 43
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 540-638 9.09e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 9.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 540 GKNHYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEK 619
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                          90
                  ....*....|....*....
gi 2734853729 620 AIADYNSCLVLNPNLPDVA 638
Cdd:TIGR02917 382 AAEYLAKATELDPENAAAR 400
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 543-633 1.20e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 543 HYQQGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIA 622
Cdd:TIGR02917 441 YLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQ 520

                          90
                  ....*....|.
gi 2734853729 623 DYNSCLVLNPN 633
Cdd:TIGR02917 521 RFEKVLTIDPK 531
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 543-624 1.43e-03

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 41.38  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 543 HYQQGEYTTAI---DDFTQvllLKPNSPD---ANYNRGLAYGKL--------GEYSAAIEDYNQTLRLNPN--------- 599
Cdd:TIGR03302  80 YYKSGDYAEAIaaaDRFIR---LHPNHPDadyAYYLRGLSNYNQidrvdrdqTAAREAFEAFQELIRRYPNseyapdakk 156

                          90       100
                  ....*....|....*....|....*
gi 2734853729 600 YLRAYNNRantyykLGEYEKAIADY 624
Cdd:TIGR03302 157 RMDYLRNR------LAGKELYVARF 175
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 549-641 1.93e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.89  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2734853729 549 YTTAIDDFTQVLL---LKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYN 625
Cdd:TIGR00990 310 YEEAARAFEKALDlgkLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFD 389

                          90
                  ....*....|....*.
gi 2734853729 626 SCLVLNPNLPDVAHNR 641
Cdd:TIGR00990 390 KALKLNSEDPDIYYHR 405
TPR_12 pfam13424
Tetratricopeptide repeat;
537-596 2.16e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.16e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2734853729 537 YQRGKNHYQQGEYTTAIDDFTQVL-----LLKPNSPD---ANYNRGLAYGKLGEYSAAIEDYNQTLRL 596
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALeiarrLLGPDHPLtatTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_8 pfam13181
Tetratricopeptide repeat;
568-599 2.28e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.22  E-value: 2.28e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2734853729 568 DANYNRGLAYGKLGEYSAAIEDYNQTLRLNPN 599
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 533-565 2.70e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 2.70e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2734853729 533 VKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPN 565
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_19 pfam14559
Tetratricopeptide repeat;
546-609 3.20e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.79  E-value: 3.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2734853729 546 QGEYTTAIDDFTQVLLLKPNSPDANYNRGLAYGKLGEYSAAIEDYNQTLRLNPNYLRAYNNRAN 609
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAK 64
TPR_1 pfam00515
Tetratricopeptide repeat;
533-565 3.29e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 3.29e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2734853729 533 VKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPN 565
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
ycf3 CHL00033
photosystem I assembly protein Ycf3
 571-640 3.45e-03

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 39.22  E-value: 3.45e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 571 YNRGLAYGKLGEYSAAIEDYNQTLRLNPN-YLRAY--NNRANTYYKLGEYEKAIADYNSCLVLNPNLPDVAHN 640
Cdd:CHL00033   39 YRDGMSAQSEGEYAEALQNYYEAMRLEIDpYDRSYilYNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNN 111
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 533-565 4.13e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 4.13e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2734853729  533 VKICYQRGKNHYQQGEYTTAIDDFTQVLLLKPN 565
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 581-633 7.27e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.27e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2734853729 581 GEYSAAIEDYNQTLRLNPNYLRAYNNRANTYYKLGEYEKAIADYNSCLVLNPN 633
Cdd:cd24142    14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPD 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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